Hub : Traits :

Qualifications: A levels/AS levels or equivalent

381 significantly associated models · 88 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 41130424 42542658 1 1 2.3e-07 3.0e-07 9.4e-04 58 FOXO6
2 1 43152610 45153116 9 4 3.1e-12 3.9e-13 8.2e-01 100 ARTN MED8 ST3GAL3
3 1 71163715 73435171 1 1 8.2e-08 1.8e-08 1.8e-06 28 NEGR1
4 1 93121330 94534354 1 1 4.6e-08 2.8e-07 1.0e-01 90 DR1
5 1 106906072 108296508 1 1 3.6e-07 1.0e-05 7.9e-02 84 PRMT6
6 1 212468974 213877776 1 1 2.4e-07 1.1e-06 4.7e-01 98 ANGEL2
7 1 242600606 244359621 2 1 2.7e-08 2.7e-08 1.0e+00 100 RP11-261C10.5
8 2 43899918 45698128 1 1 3.0e-08 5.4e-10 5.0e-03 80 CAMKMT
9 2 100193898 101731705 2 1 1.2e-09 2.4e-10 7.2e-02 92 CHST10
10 2 156594333 158165818 1 1 8.3e-09 5.1e-09 3.2e-03 74 GPD2
11 2 161297929 162790882 1 1 4.0e-08 5.3e-10 1.5e-03 74 TANK
12 2 207989470 209578600 1 1 2.8e-07 5.8e-08 1.0e+00 100 PLEKHM3
13 3 48029118 51043528 26 1 3.9e-26 1.4e-23 4.3e-02 96 MST1R
14 4 105598022 107092169 1 1 3.5e-07 2.5e-07 7.5e-02 88 PPA2
15 4 151637154 153275701 1 1 2.4e-07 8.6e-08 1.2e-04 48 FAM160A1
16 5 59353199 61156570 4 1 7.1e-09 5.9e-09 1.1e-01 92 ERCC8
17 6 13226792 14671877 1 1 2.2e-10 2.0e-08 8.2e-02 90 RNF182
18 6 118559487 120165475 2 1 1.0e-07 3.1e-06 5.5e-01 98 RP11-351A11.1
19 7 1161158 5003373 2 2 6.1e-08 1.5e-08 1.2e-02 80 MAD1L1 SDK1
20 7 23913624 25432157 1 1 9.6e-09 5.5e-09 1.0e+00 100 MPP6
21 7 74016979 75842792 6 1 2.4e-07 4.2e-07 4.8e-01 98 STAG3L1
22 7 131775747 133453874 1 1 2.3e-07 2.2e-11 3.4e-11 2 CHCHD3
23 8 142629143 144515639 2 2 1.7e-08 2.6e-09 4.7e-03 78 THEM6 TSNARE1
24 10 10349662 12076043 1 1 7.6e-08 1.1e-08 7.2e-03 78 CELF2
25 10 64195778 65606229 1 1 1.4e-08 8.9e-09 6.0e-02 89 NRBF2
26 11 94805896 96276010 4 1 2.9e-13 1.1e-12 3.8e-01 98 AP001877.1
27 12 122713991 124591385 10 1 8.9e-15 7.4e-15 1.0e+00 100 ABCB9
28 16 11447272 13364255 1 1 2.6e-08 3.7e-07 1.7e-03 62 SNX29
29 17 43000481 43913030 1 1 3.3e-07 6.2e-06 1.0e+00 100 CRHR1-IT1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Crohns Disease (2017) 1.50 1 1 3.0 0.00 1.0e+00 MST1R
Irritable Bowel Disease (IBD) 1.90 1 1 3.0 0.00 1.0e+00 MST1R
Ulcerative Colitis (UC) 1.96 1 1 3.0 0.00 1.0e+00 MST1R
Major Depression (MDD) 2.70 1 1 3.0 0.00 1.0e+00 NEGR1
Reaction Time 1.62 1 0 0.0 0.00 1.0e+00 RP11-261C10.5
Verbal and Numeric Reasoning (VNR) 7.46 15 8 24.2 -0.95 1.7e-08 ABCB9 AP001877.1 ARTN CHST10 CRHR1-IT1 FAM160A1 FOXO6 MED8 MST1R NEGR1 PPA2 RNF182 SNX29 ST3GAL3 TANK
Breast Cancer 1.70 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Ovarian Cancer 2.00 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Prostate Cancer 1.33 1 0 0.0 0.00 1.0e+00 PPA2
Age at First Birth 3.13 1 1 3.0 0.00 1.0e+00 MST1R
Body Mass Index (BMI) (2010) 3.07 2 1 3.0 0.00 1.0e+00 NEGR1 STAG3L1
Crohns Disease (2012) 1.84 1 1 3.0 0.00 1.0e+00 MST1R
HDL Cholesterol 1.47 2 0 0.0 0.00 1.0e+00 DR1 NRBF2
Neuroticism 2.36 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 TANK
Primary Biliary Cirrhosis 1.45 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Schizophrenia 2.67 5 2 6.1 -0.54 3.4e-01 ABCB9 CRHR1-IT1 RP11-261C10.5 ST3GAL3 TSNARE1
Triglycerides 1.57 1 1 3.0 0.00 1.0e+00 NRBF2
Ulcerative Colitis 1.91 1 1 3.0 0.00 1.0e+00 MST1R
Blood Eosinophil Count 1.12 3 2 6.1 0.00 1.0e+00 ABCB9 CRHR1-IT1 DR1
Blood Platelet Count 3.80 7 3 9.1 0.24 6.0e-01 ABCB9 CRHR1-IT1 DR1 FAM160A1 MPP6 NRBF2 ST3GAL3
Blood Red Count 2.36 10 4 12.1 0.25 4.9e-01 ABCB9 AP001877.1 CAMKMT CRHR1-IT1 DR1 ERCC8 MED8 MST1R NRBF2 ST3GAL3
Blood White Count 2.10 8 4 12.1 0.44 2.8e-01 CRHR1-IT1 FAM160A1 FOXO6 MED8 MPP6 MST1R NRBF2 PPA2
Heel T-Score 1.38 4 4 12.1 0.35 6.5e-01 ABCB9 CRHR1-IT1 MST1R NEGR1
BMI 3.51 9 7 21.2 0.70 3.8e-02 CAMKMT CHST10 MST1R NEGR1 NRBF2 PRMT6 SNX29 STAG3L1 THEM6
Height 1.35 15 9 27.3 -0.84 8.6e-05 ABCB9 AP001877.1 CAMKMT CRHR1-IT1 DR1 ERCC8 FAM160A1 MED8 MPP6 MST1R NRBF2 PPA2 SNX29 ST3GAL3 STAG3L1
Waist Hip Ratio (WHR) 1.71 2 2 6.1 0.00 1.0e+00 ABCB9 CRHR1-IT1
Systolic Blood Pressure 1.88 6 3 9.1 -0.01 9.8e-01 CRHR1-IT1 MED8 MPP6 RP11-261C10.5 STAG3L1 TSNARE1
Smoking Status 3.55 7 3 9.1 0.99 2.1e-05 CELF2 ERCC8 MED8 PRMT6 SDK1 ST3GAL3 TANK
Allergy or Eczema 1.66 3 0 0.0 0.00 1.0e+00 ABCB9 DR1 NEGR1
Cardiovascular Disease 2.11 6 1 3.0 0.45 3.7e-01 MED8 NEGR1 RP11-261C10.5 STAG3L1 THEM6 TSNARE1
Hypothyroidism (self reported) 1.39 1 1 3.0 0.00 1.0e+00 TANK
Respiratory disease 1.35 1 0 0.0 0.00 1.0e+00 SDK1
Type 2 Diabetes (T2D) 1.33 1 0 0.0 0.00 1.0e+00 MST1R
Lung FEV1/FVC ratio 1.71 4 3 9.1 0.33 6.7e-01 CRHR1-IT1 NEGR1 NRBF2 PPA2
Lung FVC 2.31 7 2 6.1 -0.09 8.5e-01 ABCB9 CRHR1-IT1 ERCC8 FOXO6 GPD2 MST1R NRBF2
Neuroticism 3.09 3 1 3.0 0.00 1.0e+00 CRHR1-IT1 SNX29 TSNARE1
Chronotype (morning person) 1.60 1 0 0.0 0.00 1.0e+00 CAMKMT
Hair Pigment 0.12 2 1 3.0 0.00 1.0e+00 ABCB9 CRHR1-IT1
Hand grip strength (left) 1.32 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 FAM160A1
Number of treatments/medications taken 2.89 4 1 3.0 -0.64 3.6e-01 MST1R NEGR1 RP11-261C10.5 TANK
Sensitivity / hurt feelings 3.07 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Frequency of depressed mood in last 2 weeks 2.28 2 0 0.0 0.00 1.0e+00 CELF2 CRHR1-IT1
Hearing difficulty/problems: Yes 1.37 1 0 0.0 0.00 1.0e+00 SDK1
Relative age of first facial hair 3.08 3 1 3.0 0.00 1.0e+00 CRHR1-IT1 MED8 NRBF2
Systolic blood pressure, automated reading 2.38 6 3 9.1 -0.18 7.4e-01 CRHR1-IT1 MED8 MPP6 PPA2 STAG3L1 TSNARE1
Supplements: Zinc 2.14 1 0 0.0 0.00 1.0e+00 NRBF2
Medication: Co-codamol 1.54 1 0 0.0 0.00 1.0e+00 MST1R
Pack years adult smoking proportion 2.45 2 0 0.0 0.00 1.0e+00 CHCHD3 SNX29
Impedance of leg (right) 1.75 8 3 9.1 -0.07 8.6e-01 AP001877.1 CRHR1-IT1 ERCC8 FAM160A1 MST1R NEGR1 PPA2 STAG3L1
Leg fat-free mass (left) 1.88 8 7 21.2 0.09 8.4e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Trunk fat percentage 2.79 9 5 15.2 -0.61 8.4e-02 ANGEL2 CHST10 CRHR1-IT1 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Hand grip strength (right) 1.42 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 FAM160A1
Current tobacco smoking 2.79 1 0 0.0 0.00 1.0e+00 ST3GAL3
Maternal smoking around birth 2.70 1 0 0.0 0.00 1.0e+00 MED8
Fed-up feelings 3.74 4 2 6.1 -0.95 5.1e-02 ABCB9 CRHR1-IT1 MST1R THEM6
Relative age voice broke 2.79 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 NRBF2
Taking other prescription medications 2.25 2 1 3.0 0.00 1.0e+00 MST1R SDK1
Age when periods started (menarche) 3.62 7 4 12.1 -0.51 2.4e-01 CRHR1-IT1 MED8 MST1R NEGR1 NRBF2 ST3GAL3 STAG3L1
Heel bone mineral density (BMD) T-score, automated (left) 1.09 1 0 0.0 0.00 1.0e+00 MST1R
Qualifications: CSEs or equivalent 3.16 3 0 0.0 0.00 1.0e+00 FOXO6 MST1R ST3GAL3
High blood pressure 2.49 7 0 0.0 -0.46 3.0e-01 MED8 NEGR1 NRBF2 RP11-261C10.5 RP11-351A11.1 STAG3L1 TSNARE1
Hayfever, allergic rhinitis or eczema 1.63 3 0 0.0 0.00 1.0e+00 ABCB9 DR1 NEGR1
Sitting height 2.06 6 4 12.1 0.94 5.8e-03 ABCB9 CAMKMT CRHR1-IT1 MED8 PPA2 ST3GAL3
Body mass index (BMI) 3.44 9 4 12.1 -0.74 2.2e-02 CAMKMT CHST10 MPP6 MST1R NEGR1 NRBF2 PRMT6 STAG3L1 THEM6
Impedance of leg (left) 1.87 9 4 12.1 -0.11 7.7e-01 ABCB9 AP001877.1 CRHR1-IT1 ERCC8 FAM160A1 MST1R NEGR1 PPA2 STAG3L1
Leg predicted mass (left) 1.91 8 7 21.2 0.09 8.3e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Trunk fat mass 2.56 6 4 12.1 -0.69 1.3e-01 CHST10 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Waist circumference 2.74 6 4 12.1 -0.66 1.6e-01 CHST10 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Past tobacco smoking 2.57 3 0 0.0 0.00 1.0e+00 CELF2 CRHR1-IT1 TANK
Alcohol usually taken with meals 4.37 5 1 3.0 1.00 7.1e-06 ERCC8 MED8 NEGR1 NRBF2 TSNARE1
Nervous feelings 2.16 3 1 3.0 0.00 1.0e+00 AP001877.1 CRHR1-IT1 TSNARE1
Frequency of tenseness / restlessness in last 2 weeks 2.62 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Hearing difficulty/problems with background noise 1.56 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Hair/balding pattern: Pattern 2 1.77 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Had other major operations 1.90 1 0 0.0 0.00 1.0e+00 PPA2
Forced vital capacity (FVC) 2.32 5 2 6.1 0.53 3.5e-01 CRHR1-IT1 FAM160A1 FOXO6 MST1R PPA2
Heel bone mineral density (BMD) T-score, automated (right) 1.01 1 0 0.0 0.00 1.0e+00 MST1R
Ever unenthusiastic/disinterested for a whole week 2.06 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Qualifications: None of the above 12.21 23 15 45.5 -0.99 1.3e-18 ABCB9 AP001877.1 ARTN CAMKMT CELF2 CHCHD3 CHST10 DR1 ERCC8 FAM160A1 MED8 MPP6 MST1R NEGR1 NRBF2 PPA2 RNF182 RP11-261C10.5 SDK1 ST3GAL3 TANK THEM6 TSNARE1
Mouth/teeth dental problems 2.52 2 0 0.0 0.00 1.0e+00 CRHR1-IT1 RP11-261C10.5
Allergy 1.53 2 1 3.0 0.00 1.0e+00 ABCB9 NEGR1
Fluid intelligence score 7.83 15 8 24.2 0.98 4.4e-11 ABCB9 ARTN CAMKMT CELF2 CHST10 CRHR1-IT1 FAM160A1 FOXO6 MED8 MST1R NEGR1 PPA2 SNX29 ST3GAL3 TANK
Illnesses of siblings 2.66 1 0 0.0 0.00 1.0e+00 ST3GAL3
Neuroticism score 2.89 2 1 3.0 0.00 1.0e+00 CELF2 CRHR1-IT1
Weight 2.31 6 4 12.1 -0.54 2.7e-01 ABCB9 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Impedance of arm (right) 2.24 7 6 18.2 0.55 2.1e-01 CRHR1-IT1 ERCC8 MST1R NEGR1 NRBF2 PRMT6 STAG3L1
Arm fat percentage (right) 2.83 8 3 9.1 -0.73 4.1e-02 CAMKMT CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Trunk fat-free mass 1.72 8 5 15.2 0.40 3.3e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PLEKHM3 PPA2 PRMT6
Hip circumference 2.09 7 3 9.1 -0.45 3.1e-01 ABCB9 CHST10 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Alcohol intake versus 10 years previously 3.14 3 1 3.0 0.00 1.0e+00 ARTN MST1R NEGR1
Worrier / anxious feelings 2.40 2 2 6.1 0.00 1.0e+00 AP001877.1 CRHR1-IT1
Frequency of tiredness / lethargy in last 2 weeks 2.68 2 0 0.0 0.00 1.0e+00 PRMT6 SDK1
Hair/balding pattern: Pattern 3 2.40 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Number of live births 1.90 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Forced expiratory volume in 1-second (FEV1) 2.66 4 2 6.1 0.72 2.8e-01 CRHR1-IT1 GPD2 MST1R PPA2
Mouth/teeth dental problems: Dentures 3.23 2 0 0.0 0.00 1.0e+00 DR1 MST1R
Medication: Ibuprofen (e.g. Nurofen) 2.06 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Forced expiratory volume in 1-second (FEV1), Best measure 2.87 3 2 6.1 0.00 1.0e+00 CRHR1-IT1 MST1R PPA2
Impedance of arm (left) 2.23 8 5 15.2 0.63 9.5e-02 CRHR1-IT1 ERCC8 MST1R NEGR1 NRBF2 PRMT6 SNX29 STAG3L1
Arm fat mass (right) 2.95 6 4 12.1 -0.69 1.3e-01 CHST10 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Trunk predicted mass 1.74 8 4 12.1 0.40 3.2e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PLEKHM3 PPA2 PRMT6
Standing height 1.42 9 6 18.2 0.97 1.4e-05 ABCB9 CAMKMT CRHR1-IT1 FAM160A1 MED8 MPP6 NRBF2 PPA2 STAG3L1
Breastfed as a baby 2.36 1 0 0.0 0.00 1.0e+00 ABCB9
Seen doctor (GP) for nerves, anxiety, tension or depression 2.47 1 1 3.0 0.00 1.0e+00 NEGR1
Hair/balding pattern: Pattern 4 3.36 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Birth weight of first child 1.62 2 1 3.0 0.00 1.0e+00 PPA2 STAG3L1
Peak expiratory flow (PEF) 2.03 1 1 3.0 0.00 1.0e+00 CRHR1-IT1
Ever highly irritable/argumentative for 2 days 2.09 1 0 0.0 0.00 1.0e+00 MST1R
Qualifications: O levels/GCSEs or equivalent 8.44 12 3 9.1 0.98 6.8e-08 ABCB9 AP001877.1 ARTN CAMKMT FAM160A1 GPD2 MPP6 MST1R NRBF2 ST3GAL3 THEM6 TSNARE1
Medication: Paracetamol 3.58 2 2 6.1 0.00 1.0e+00 CRHR1-IT1 RP11-261C10.5
Headache pain in last month 2.53 2 2 6.1 0.00 1.0e+00 CRHR1-IT1 RP11-261C10.5
Hypothyroidism/myxoedema (self-reported) 1.23 1 0 0.0 0.00 1.0e+00 TANK
Medication: Amlodipine 1.68 1 0 0.0 0.00 1.0e+00 RP11-261C10.5
Birth weight 1.14 1 0 0.0 0.00 1.0e+00 PPA2
High blood pressure (siblings) 2.69 1 0 0.0 0.00 1.0e+00 TANK
Forced vital capacity (FVC), Best measure 2.59 4 2 6.1 0.06 9.4e-01 CRHR1-IT1 FOXO6 MST1R PPA2
Body fat percentage 3.23 9 5 15.2 -0.76 1.7e-02 ANGEL2 CAMKMT CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Leg fat percentage (right) 3.96 10 5 15.2 -0.78 7.2e-03 AP001877.1 CAMKMT CHST10 MPP6 MST1R NEGR1 PRMT6 SNX29 STAG3L1 THEM6
Arm fat-free mass (right) 1.90 8 5 15.2 0.09 8.3e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Exposure to tobacco smoke outside home 2.66 1 0 0.0 0.00 1.0e+00 RP11-261C10.5
Comparative body size at age 10 2.26 2 1 3.0 0.00 1.0e+00 ERCC8 NEGR1
Number of full brothers 1.92 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Worry too long after embarrassment 1.82 2 0 0.0 0.00 1.0e+00 CRHR1-IT1 THEM6
Wheeze or whistling in the chest in last year 2.31 1 1 3.0 0.00 1.0e+00 MST1R
Age at first live birth 4.67 3 1 3.0 0.00 1.0e+00 AP001877.1 MST1R NRBF2
Health satisfaction 1.90 1 0 0.0 0.00 1.0e+00 TSNARE1
Qualifications: College or University degree 13.03 30 18 54.5 0.97 9.3e-20 ABCB9 AP001877.1 ARTN CAMKMT CELF2 CHCHD3 CHST10 CRHR1-IT1 DR1 ERCC8 FAM160A1 FOXO6 GPD2 MAD1L1 MED8 MPP6 MST1R NEGR1 NRBF2 PPA2 RNF182 RP11-261C10.5 RP11-351A11.1 SDK1 SNX29 ST3GAL3 STAG3L1 TANK THEM6 TSNARE1
Medication for pain relief, constipation, heartburn 3.00 3 1 3.0 0.00 1.0e+00 ABCB9 CRHR1-IT1 RP11-261C10.5
Medication: Blood pressure 1.92 1 0 0.0 0.00 1.0e+00 STAG3L1
Medication: Ibuprofen 1.70 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Whole body fat mass 2.89 7 4 12.1 -0.71 7.2e-02 CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Leg fat mass (right) 3.39 7 4 12.1 -0.72 6.9e-02 CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Arm predicted mass (right) 1.90 8 5 15.2 0.08 8.6e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Pulse rate, automated reading 1.54 4 2 6.1 -0.49 5.1e-01 MST1R NEGR1 RP11-351A11.1 STAG3L1
Alcohol intake frequency. 2.96 5 2 6.1 -0.75 1.5e-01 ABCB9 CRHR1-IT1 MST1R NEGR1 TSNARE1
Comparative height size at age 10 1.87 8 4 12.1 0.79 2.0e-02 ABCB9 CAMKMT CRHR1-IT1 DR1 FAM160A1 MED8 PLEKHM3 ST3GAL3
Overall health rating 4.47 6 3 9.1 -0.98 7.1e-04 MST1R RP11-261C10.5 STAG3L1 TANK THEM6 TSNARE1
Age at last live birth 3.91 2 1 3.0 0.00 1.0e+00 AP001877.1 MST1R
Leg pain on walking 2.24 1 1 3.0 0.00 1.0e+00 MST1R
Qualifications: NVQ or HND or HNC or equivalent 1.85 1 0 0.0 0.00 1.0e+00 MST1R
Commuting to job workplace: Car/motor vehicle 2.72 1 0 0.0 0.00 1.0e+00 NEGR1
Knee pain experienced in last month 2.28 1 0 0.0 0.00 1.0e+00 RP11-261C10.5
Hypertension (Self-reported) 2.41 8 0 0.0 -0.75 3.2e-02 MPP6 NEGR1 NRBF2 RP11-261C10.5 RP11-351A11.1 STAG3L1 THEM6 TSNARE1
Whole body fat-free mass 1.79 9 6 18.2 0.22 5.6e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PLEKHM3 PPA2 PRMT6 STAG3L1
Leg fat-free mass (right) 1.83 8 7 21.2 0.13 7.5e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Arm fat percentage (left) 2.86 8 4 12.1 -0.72 4.5e-02 CAMKMT CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Average weekly red wine intake 5.22 4 1 3.0 0.97 3.1e-02 ABCB9 AP001877.1 CAMKMT NRBF2
Handedness (chirality/laterality): Left-handed 1.55 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Mood swings 3.32 3 1 3.0 0.00 1.0e+00 CELF2 CRHR1-IT1 MST1R
Loneliness, isolation 2.03 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Long-standing illness, disability or infirmity 1.49 1 0 0.0 0.00 1.0e+00 NEGR1
Friendships satisfaction 1.86 1 0 0.0 0.00 1.0e+00 AP001877.1
Qualifications: nursing, teaching 7.13 11 3 9.1 0.97 7.7e-07 ABCB9 AP001877.1 CELF2 ERCC8 FAM160A1 MAD1L1 MST1R NEGR1 PPA2 RP11-261C10.5 ST3GAL3
Mouth/teeth dental problems: Mouth ulcers 2.23 2 1 3.0 0.00 1.0e+00 AP001877.1 CRHR1-IT1
Medication for cholesterol 2.03 1 0 0.0 0.00 1.0e+00 TANK
Back pain experienced in last month 2.25 1 0 0.0 0.00 1.0e+00 SNX29
Smoking status: Current 2.68 1 1 3.0 0.00 1.0e+00 ST3GAL3
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.54 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 PPA2
Whole body water mass 1.84 9 6 18.2 0.22 5.6e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PLEKHM3 PPA2 PRMT6 STAG3L1
Leg predicted mass (right) 1.83 8 7 21.2 0.13 7.5e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Arm fat mass (left) 2.93 6 4 12.1 -0.68 1.3e-01 CHST10 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Number of self-reported non-cancer illnesses 1.63 1 1 3.0 0.00 1.0e+00 NEGR1
Average weekly champagne plus white wine intake 2.53 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Miserableness 3.28 5 2 6.1 -0.94 1.8e-02 CELF2 CRHR1-IT1 MST1R RP11-261C10.5 TANK
Guilty feelings 2.09 1 0 0.0 0.00 1.0e+00 CRHR1-IT1
Mother's age at death 1.99 1 0 0.0 0.00 1.0e+00 RP11-261C10.5
Commuting to job workplace: Public transport 3.45 2 0 0.0 0.00 1.0e+00 CHST10 NEGR1
Medication: Blood pressure 1.98 2 0 0.0 0.00 1.0e+00 CRHR1-IT1 NRBF2
Medication: Paracetamol 3.37 3 1 3.0 0.00 1.0e+00 ARTN CRHR1-IT1 RP11-261C10.5
Ever smoked 2.23 1 0 0.0 0.00 1.0e+00 CELF2
Basal metabolic rate 1.86 8 7 21.2 0.09 8.4e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Leg fat percentage (left) 3.98 8 7 21.2 -0.76 2.9e-02 CAMKMT CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Arm fat-free mass (left) 1.98 8 5 15.2 0.07 8.6e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1
Number of operations (self-reported) 2.60 3 0 0.0 0.00 1.0e+00 NEGR1 PPA2 TANK
Average weekly beer plus cider intake 3.05 3 0 0.0 0.00 1.0e+00 MST1R NEGR1 NRBF2
Irritability 1.96 2 1 3.0 0.00 1.0e+00 CELF2 CRHR1-IT1
Risk taking 2.31 2 0 0.0 0.00 1.0e+00 FAM160A1 RP11-261C10.5
Diastolic blood pressure, automated reading 3.94 9 5 15.2 -0.76 1.9e-02 ABCB9 MED8 MPP6 MST1R NRBF2 RP11-261C10.5 STAG3L1 THEM6 TSNARE1
Unable to work because of sickness or disability 2.60 1 0 0.0 0.00 1.0e+00 ERCC8
Vascular/heart problems diagnosed by doctor 2.36 7 0 0.0 0.46 2.9e-01 MED8 NEGR1 NRBF2 RP11-261C10.5 RP11-351A11.1 STAG3L1 TSNARE1
Pain experienced in last month 3.07 3 1 3.0 0.00 1.0e+00 CRHR1-IT1 MST1R SDK1
Pack years of smoking 2.31 2 0 0.0 0.00 1.0e+00 PRMT6 SNX29
Impedance of whole body 2.12 8 5 15.2 0.43 2.9e-01 CRHR1-IT1 ERCC8 MST1R NEGR1 NRBF2 PPA2 PRMT6 STAG3L1
Leg fat mass (left) 3.42 7 5 15.2 -0.71 7.2e-02 CHST10 MPP6 MST1R NEGR1 PRMT6 STAG3L1 THEM6
Arm predicted mass (left) 2.01 8 5 15.2 0.07 8.8e-01 ABCB9 ERCC8 FAM160A1 MST1R NEGR1 PPA2 PRMT6 STAG3L1

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 9 0.2578 2.26
GTEx Adipose Visceral Omentum 11 0.5403 2.43
GTEx Adrenal Gland 2 0.1373 2.06
GTEx Artery Aorta 11 0.3695 2.28
GTEx Artery Coronary 2 0.1691 2.22
GTEx Artery Tibial 14 0.3722 2.27
GTEx Brain Caudate basal ganglia 3 0.3261 2.36
GTEx Brain Cerebellar Hemisphere 8 0.5373 2.56
GTEx Brain Cerebellum 7 0.3532 2.41
GTEx Brain Cortex 3 0.2899 2.32
GTEx Brain Frontal Cortex BA9 5 0.5411 2.55
GTEx Brain Hippocampus 1 0.1908 2.05
GTEx Brain Hypothalamus 2 0.3390 2.41
GTEx Brain Nucleus accumbens basal ganglia 1 0.1156 2.33
GTEx Brain Putamen basal ganglia 2 0.3205 2.42
GTEx Breast Mammary Tissue 5 0.2533 2.42
GTEx Breast Mammary Tissue (Male) 1 0.0838 2.24
GTEx Breast Mammary Tissue (Female) 6 0.3650 2.32
GTEx Cells EBV-transformed lymphocytes 3 0.2108 2.36
GTEx Cells Transformed fibroblasts 19 0.4525 2.25
GTEx Colon Sigmoid 6 0.4104 2.42
GTEx Colon Transverse 9 0.4360 2.39
GTEx Esophagus Gastroesophageal Junction 6 0.4152 2.55
GTEx Esophagus Mucosa 15 0.4518 2.37
GTEx Esophagus Muscularis 14 0.4332 2.44
GTEx Heart Atrial Appendage 4 0.2533 2.47
GTEx Heart Left Ventricle 6 0.3922 2.36
GTEx Liver 4 0.5579 2.34
GTEx Lung 11 0.3829 2.29
GTEx Muscle Skeletal 11 0.3806 2.38
GTEx Nerve Tibial 19 0.4397 2.28
GTEx Ovary 1 0.1101 2.40
GTEx Pancreas 9 0.5515 2.52
GTEx Pituitary 3 0.2691 2.21
GTEx Prostate 1 0.1198 2.35
GTEx Skin Not Sun Exposed Suprapubic 11 0.4473 2.39
GTEx Skin Sun Exposed Lower leg 14 0.3846 2.34
GTEx Small Intestine Terminal Ileum 3 0.6508 2.41
GTEx Spleen 3 0.2126 2.45
GTEx Stomach 4 0.2751 2.42
GTEx Testis 8 0.2536 2.22
GTEx Thyroid 15 0.3751 2.27
GTEx Uterus 0 0.0000 2.36
GTEx Vagina 1 0.1575 2.60
GTEx Whole Blood 4 0.2007 2.22
METSIM Adipose 12 0.2603 2.06
NTR Blood 9 0.3747 2.13
ROSMAP Brain Pre-frontal Cortex 13 0.2961 2.26
YFS Blood 9 0.1949 1.96
CommonMind Brain Pre-frontal Cortex 11 0.2047 2.07
TCGA Breast Tumor 1 0.1304 2.36
TCGA Breast Normal 14 0.3328 2.00
TCGA Ovarian Tumor 7 0.2396 2.09
TCGA Prostate Tumor 8 0.2313 2.09