Hub : Traits :

Cholesterol lowering medication

108 significantly associated models · 51 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 15752716 17413769 2 1 2.3e-07 1.1e-07 4.9e-02 86 SZRD1
2 1 26327671 27882335 3 1 1.8e-08 3.3e-06 5.3e-01 98 PIGV
3 1 62207254 63844736 2 1 8.2e-11 2.4e-10 3.8e-01 98 DOCK7
4 1 108854166 110733794 4 1 4.4e-32 9.3e-32 1.0e+00 100 PSRC1
5 2 20529948 21958745 1 1 2.1e-25 9.5e-26 1.0e+00 100 APOB
6 2 26883355 28414302 3 2 4.9e-09 7.1e-14 2.5e-02 91 FNDC4 NRBP1
7 5 73969058 75594743 3 2 8.8e-11 1.5e-14 1.0e-03 82 COL4A3BP POLK
8 6 160071844 161571560 1 2 3.2e-12 5.0e-15 1.5e-04 76 SLC22A3
9 9 106846396 108380721 1 1 2.8e-07 3.1e-07 6.4e-02 87 ABCA1
10 11 63044593 64701030 2 2 1.6e-08 1.8e-07 1.0e+00 100 COX8A VEGFB
11 11 115953897 117800682 6 2 4.1e-25 2.2e-29 2.8e-01 99 PAFAH1B2 ZNF259
12 13 46645740 48066565 1 1 1.9e-07 5.5e-08 1.0e+00 100 ESD
13 13 114052470 115106996 1 1 6.2e-08 2.7e-05 1.3e-01 87 RASA3
14 16 71374298 72800567 2 1 9.1e-08 2.0e-07 1.0e+00 100 HPR
15 17 27207120 29126951 4 1 7.1e-09 3.7e-08 2.5e-01 96 CORO6
16 17 45479446 46874272 1 1 2.3e-07 1.5e-04 9.7e-02 81 CBX1
17 19 9982334 12196190 8 10 2.1e-15 1.4e-42 NaN NaN C19orf80 CARM1 EPOR ILF3 RGL3 SMARCA4 YIPF2
18 19 44614208 46098885 3 3 2.9e-10 2.1e-86 5.9e-72 17 BCAM PVRL2 TOMM40
19 20 62008975 62912463 3 1 8.1e-09 1.8e-08 4.0e-01 98 OPRL1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in mother) 4.02 2 2 6.1 0.00 1.0e+00 BCAM TOMM40
Alzheimer’s Disease (in father) 1.21 1 0 0.0 0.00 1.0e+00 TOMM40
Alzheimer’s Disease (including proxy) 6.40 2 2 6.1 0.00 1.0e+00 BCAM TOMM40
Crohns Disease (2017) 1.42 2 0 0.0 0.00 1.0e+00 FNDC4 NRBP1
Irritable Bowel Disease (IBD) 1.25 2 0 0.0 0.00 1.0e+00 NRBP1 OPRL1
Ulcerative Colitis (UC) 1.29 1 1 3.0 0.00 1.0e+00 OPRL1
Reaction Time 1.67 2 0 0.0 0.00 1.0e+00 CARM1 YIPF2
Verbal and Numeric Reasoning (VNR) 1.03 1 0 0.0 0.00 1.0e+00 CORO6
Breast Cancer 0.79 2 0 0.0 0.00 1.0e+00 CORO6 OPRL1
Body Mass Index (BMI) (2010) 1.98 1 0 0.0 0.00 1.0e+00 POLK
Coronary Artery Disease (CAD) 6.41 5 2 6.1 -0.98 3.7e-04 EPOR PSRC1 SLC22A3 SMARCA4 ZNF259
Fasting Glucose 4.67 2 2 6.1 0.00 1.0e+00 FNDC4 NRBP1
HbA1C 1.16 1 0 0.0 0.00 1.0e+00 VEGFB
HDL Cholesterol 6.66 7 3 9.1 0.67 9.7e-02 ABCA1 APOB PIGV PSRC1 SMARCA4 TOMM40 ZNF259
LDL Cholesterol 64.85 22 17 51.5 -0.93 7.6e-12 ABCA1 APOB BCAM C19orf80 CARM1 CBX1 COL4A3BP DOCK7 EPOR HPR ILF3 PAFAH1B2 PIGV POLK PSRC1 PVRL2 RGL3 SLC22A3 SMARCA4 TOMM40 YIPF2 ZNF259
Primary Biliary Cirrhosis 3.32 5 1 3.0 -0.95 1.1e-02 CARM1 EPOR NRBP1 SMARCA4 YIPF2
Rheumatoid Arthritis 1.06 1 0 0.0 0.00 1.0e+00 OPRL1
Triglycerides 28.35 7 6 18.2 -0.87 1.1e-02 APOB DOCK7 FNDC4 HPR PAFAH1B2 SLC22A3 ZNF259
Type 2 Diabetes (T2D) 1.22 1 0 0.0 0.00 1.0e+00 VEGFB
Ulcerative Colitis 1.19 1 0 0.0 0.00 1.0e+00 PAFAH1B2
Blood Eosinophil Count 1.91 15 7 21.2 0.30 2.4e-01 BCAM CARM1 DOCK7 EPOR FNDC4 OPRL1 PAFAH1B2 PIGV PVRL2 RASA3 SMARCA4 TOMM40 VEGFB YIPF2 ZNF259
Blood Platelet Count 4.46 13 13 39.4 -0.16 6.0e-01 COL4A3BP CORO6 COX8A DOCK7 FNDC4 HPR NRBP1 PAFAH1B2 PIGV POLK SMARCA4 TOMM40 ZNF259
Blood Red Count 1.05 5 5 15.2 -0.53 3.6e-01 CBX1 CORO6 FNDC4 HPR VEGFB
Blood White Count 2.64 13 4 12.1 -0.07 8.0e-01 CARM1 CBX1 CORO6 COX8A DOCK7 FNDC4 NRBP1 OPRL1 PAFAH1B2 RASA3 SMARCA4 VEGFB YIPF2
Heel T-Score 0.68 4 1 3.0 0.99 9.8e-03 APOB CORO6 DOCK7 PSRC1
BMI 2.04 7 3 9.1 0.62 1.4e-01 COL4A3BP CORO6 FNDC4 HPR OPRL1 POLK SLC22A3
Height 1.52 14 12 36.4 0.71 1.0e-03 CARM1 CBX1 CORO6 EPOR FNDC4 ILF3 NRBP1 OPRL1 PIGV PSRC1 SLC22A3 SMARCA4 YIPF2 ZNF259
Waist Hip Ratio (WHR) 3.07 5 4 12.1 -0.98 6.5e-04 ABCA1 OPRL1 SLC22A3 SMARCA4 VEGFB
Systolic Blood Pressure 2.05 10 3 9.1 -0.94 1.5e-05 EPOR NRBP1 OPRL1 PAFAH1B2 PIGV RGL3 SLC22A3 SMARCA4 TOMM40 VEGFB
Allergy or Eczema 1.13 2 0 0.0 0.00 1.0e+00 NRBP1 PVRL2
Cardiovascular Disease 9.98 24 19 57.6 -0.98 1.6e-19 APOB BCAM CARM1 CBX1 COL4A3BP CORO6 DOCK7 EPOR FNDC4 HPR NRBP1 OPRL1 PAFAH1B2 PIGV PSRC1 PVRL2 RGL3 SLC22A3 SMARCA4 SZRD1 TOMM40 VEGFB YIPF2 ZNF259
Hypothyroidism (self reported) 1.31 1 0 0.0 0.00 1.0e+00 YIPF2
Type 2 Diabetes (T2D) 2.45 4 1 3.0 0.62 3.8e-01 FNDC4 NRBP1 POLK VEGFB
Lung FEV1/FVC ratio 1.92 4 3 9.1 -0.53 4.7e-01 CORO6 COX8A PSRC1 SZRD1
Lung FVC 0.84 2 1 3.0 0.00 1.0e+00 FNDC4 OPRL1
Hair Pigment 0.30 8 1 3.0 -0.65 4.1e-02 CARM1 CBX1 EPOR NRBP1 OPRL1 PIGV SMARCA4 YIPF2
Tanning 0.37 4 1 3.0 0.05 9.5e-01 EPOR FNDC4 NRBP1 SMARCA4
Number of treatments/medications taken 3.54 2 1 3.0 0.00 1.0e+00 NRBP1 PSRC1
Hearing difficulty/problems: Yes 1.20 1 0 0.0 0.00 1.0e+00 CBX1
Relative age of first facial hair 1.34 3 0 0.0 0.00 1.0e+00 FNDC4 NRBP1 POLK
Systolic blood pressure, automated reading 1.53 2 1 3.0 0.00 1.0e+00 OPRL1 PIGV
Angina 5.25 4 1 3.0 1.00 4.5e-05 C19orf80 OPRL1 PSRC1 SLC22A3
Medication: Metformin 2.16 1 0 0.0 0.00 1.0e+00 NRBP1
Diabetes (father) 1.75 1 0 0.0 0.00 1.0e+00 NRBP1
Diabetes (mother) 2.13 1 0 0.0 0.00 1.0e+00 FNDC4
Impedance of leg (right) 1.55 7 2 6.1 0.80 3.0e-02 CBX1 COL4A3BP FNDC4 NRBP1 OPRL1 POLK SZRD1
Leg fat-free mass (left) 2.55 7 5 15.2 -0.93 3.5e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK SLC22A3 SMARCA4
Trunk fat percentage 1.42 5 1 3.0 -0.69 2.0e-01 BCAM COL4A3BP HPR POLK SLC22A3
Hand grip strength (right) 1.02 1 0 0.0 0.00 1.0e+00 SLC22A3
Townsend deprivation index at recruitment 0.70 1 0 0.0 0.00 1.0e+00 CORO6
High blood pressure 2.29 5 2 6.1 1.00 3.6e-04 CBX1 CORO6 OPRL1 PIGV VEGFB
Hayfever, allergic rhinitis or eczema 1.37 2 0 0.0 0.00 1.0e+00 NRBP1 PVRL2
Sitting height 1.41 7 3 9.1 -0.50 2.1e-01 CORO6 FNDC4 HPR NRBP1 PIGV SLC22A3 SMARCA4
High blood pressure (mother) 1.64 1 1 3.0 0.00 1.0e+00 PIGV
Body mass index (BMI) 1.88 5 2 6.1 -0.50 3.9e-01 COL4A3BP CORO6 FNDC4 HPR POLK
Impedance of leg (left) 1.56 6 2 6.1 0.79 6.2e-02 CBX1 COL4A3BP FNDC4 NRBP1 OPRL1 POLK
Leg predicted mass (left) 2.56 8 5 15.2 -0.88 7.4e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Trunk fat mass 1.74 5 3 9.1 -0.72 1.0e-01 BCAM COL4A3BP HPR POLK SLC22A3
Waist circumference 1.66 4 2 6.1 -0.44 5.6e-01 COL4A3BP CORO6 HPR POLK
Number of incorrect matches in round 1.05 1 0 0.0 0.00 1.0e+00 CORO6
Had menopause 1.63 1 1 3.0 0.00 1.0e+00 NRBP1
Forced vital capacity (FVC) 1.19 5 0 0.0 -0.99 2.0e-03 CARM1 CORO6 EPOR SMARCA4 YIPF2
Qualifications: None of the above 0.71 1 0 0.0 0.00 1.0e+00 RASA3
Heart attack 4.25 3 1 3.0 0.00 1.0e+00 C19orf80 PSRC1 SLC22A3
Allergy 1.18 1 0 0.0 0.00 1.0e+00 PVRL2
Diabetes (self-reported) 2.18 2 1 3.0 0.00 1.0e+00 NRBP1 POLK
Medication: Ramipril 2.24 1 0 0.0 0.00 1.0e+00 SLC22A3
Medication: Simvastatin 22.59 26 16 48.5 0.99 1.0e-23 APOB BCAM C19orf80 CARM1 CBX1 COL4A3BP COX8A DOCK7 EPOR FNDC4 HPR NRBP1 OPRL1 PAFAH1B2 PIGV POLK PSRC1 PVRL2 RGL3 SLC22A3 SMARCA4 SZRD1 TOMM40 VEGFB YIPF2 ZNF259
Fluid intelligence score 1.32 1 0 0.0 0.00 1.0e+00 CORO6
Illnesses of siblings 2.62 2 0 0.0 0.00 1.0e+00 CORO6 HPR
Weight 2.41 8 5 15.2 -0.80 5.6e-03 COL4A3BP EPOR FNDC4 HPR NRBP1 POLK SLC22A3 SMARCA4
Impedance of arm (right) 1.84 6 3 9.1 0.79 6.1e-02 CBX1 COL4A3BP FNDC4 NRBP1 OPRL1 POLK
Arm fat percentage (right) 1.49 4 2 6.1 -0.45 5.5e-01 COL4A3BP CORO6 HPR POLK
Trunk fat-free mass 3.00 9 8 24.2 -0.89 5.2e-05 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4 YIPF2
Hip circumference 2.48 9 3 9.1 -0.81 4.5e-03 ABCA1 COL4A3BP FNDC4 HPR OPRL1 POLK SLC22A3 SMARCA4 VEGFB
Alcohol intake versus 10 years previously 1.98 2 1 3.0 0.00 1.0e+00 FNDC4 NRBP1
Father's age at death 1.59 1 0 0.0 0.00 1.0e+00 PSRC1
Number of live births 1.29 1 0 0.0 0.00 1.0e+00 COX8A
Forced expiratory volume in 1-second (FEV1) 1.17 4 0 0.0 -1.00 6.2e-05 EPOR OPRL1 SMARCA4 YIPF2
Pulse rate 1.81 2 0 0.0 0.00 1.0e+00 FNDC4 NRBP1
Mouth/teeth dental problems: Dentures 0.81 1 0 0.0 0.00 1.0e+00 FNDC4
Asthma 2.08 3 0 0.0 -0.98 2.4e-02 CARM1 SMARCA4 YIPF2
Medication: Cholesterol lowering 23.81 24 16 48.5 0.98 1.9e-19 APOB BCAM C19orf80 CARM1 CBX1 COL4A3BP DOCK7 EPOR FNDC4 HPR NRBP1 OPRL1 PAFAH1B2 PIGV POLK PSRC1 PVRL2 RGL3 SLC22A3 SMARCA4 TOMM40 VEGFB YIPF2 ZNF259
Prospective memory result 1.37 1 0 0.0 0.00 1.0e+00 CORO6
Forced expiratory volume in 1-second (FEV1), Best measure 1.31 4 0 0.0 -1.00 3.6e-05 CARM1 EPOR SMARCA4 YIPF2
Pulse wave Arterial Stiffness index 1.39 1 0 0.0 0.00 1.0e+00 VEGFB
Impedance of arm (left) 1.99 6 3 9.1 0.81 5.0e-02 CBX1 COL4A3BP FNDC4 NRBP1 OPRL1 POLK
Arm fat mass (right) 2.03 5 2 6.1 -0.58 2.3e-01 COL4A3BP CORO6 HPR POLK SLC22A3
Trunk predicted mass 2.98 9 8 24.2 -0.89 5.3e-05 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4 YIPF2
Standing height 1.64 11 8 24.2 -0.86 6.9e-05 CARM1 CBX1 CORO6 EPOR FNDC4 NRBP1 PIGV PSRC1 SLC22A3 SMARCA4 YIPF2
Birth weight of first child 1.84 2 0 0.0 0.00 1.0e+00 OPRL1 SMARCA4
Peak expiratory flow (PEF) 1.33 1 0 0.0 0.00 1.0e+00 CORO6
Pulse wave reflection index 2.17 1 0 0.0 0.00 1.0e+00 SLC22A3
Medication for cholesterol, blood pressure or diabetes 9.71 17 6 18.2 -0.99 1.4e-15 APOB BCAM C19orf80 CARM1 CBX1 COL4A3BP EPOR HPR NRBP1 OPRL1 PAFAH1B2 PIGV PSRC1 SMARCA4 TOMM40 YIPF2 ZNF259
Gout (self-reported) 4.82 3 2 6.1 0.00 1.0e+00 FNDC4 NRBP1 PIGV
Hypothyroidism/myxoedema (self-reported) 1.36 1 0 0.0 0.00 1.0e+00 YIPF2
Chronic bronchitis/emphysema (mother) 1.47 1 0 0.0 0.00 1.0e+00 BCAM
High blood pressure (siblings) 1.94 1 0 0.0 0.00 1.0e+00 CORO6
Forced vital capacity (FVC), Best measure 1.29 5 0 0.0 -0.99 7.9e-04 CARM1 CORO6 EPOR SMARCA4 YIPF2
Body fat percentage 1.48 6 2 6.1 -0.56 2.5e-01 BCAM COL4A3BP CORO6 HPR POLK SLC22A3
Leg fat percentage (right) 1.39 5 3 9.1 -0.43 4.7e-01 BCAM COL4A3BP CORO6 HPR POLK
Arm fat-free mass (right) 2.95 8 6 18.2 -0.88 3.2e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Comparative body size at age 10 1.01 1 1 3.0 0.00 1.0e+00 POLK
Worry too long after embarrassment 0.86 1 0 0.0 0.00 1.0e+00 POLK
Pulse wave peak to peak time 1.38 1 0 0.0 0.00 1.0e+00 VEGFB
Medication for pain relief, constipation, heartburn 0.97 1 0 0.0 0.00 1.0e+00 NRBP1
Medication: Blood pressure 1.91 1 0 0.0 0.00 1.0e+00 OPRL1
Angina (self-reported) 5.48 4 1 3.0 1.00 9.9e-05 C19orf80 OPRL1 PSRC1 SLC22A3
Medication: Allopurinol 4.05 3 2 6.1 0.00 1.0e+00 FNDC4 NRBP1 PIGV
Heart disease (mother) 3.89 1 0 0.0 0.00 1.0e+00 SLC22A3
Whole body fat mass 1.84 5 3 9.1 -0.72 1.1e-01 BCAM COL4A3BP HPR POLK SLC22A3
Leg fat mass (right) 2.00 6 2 6.1 -0.57 2.4e-01 BCAM COL4A3BP CORO6 HPR POLK SLC22A3
Arm predicted mass (right) 2.91 8 5 15.2 -0.88 4.2e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Pulse rate, automated reading 2.42 5 2 6.1 0.46 4.3e-01 APOB BCAM DOCK7 FNDC4 NRBP1
Alcohol intake frequency. 3.44 3 2 6.1 0.00 1.0e+00 CORO6 FNDC4 NRBP1
Comparative height size at age 10 1.45 6 3 9.1 -0.77 4.3e-02 CORO6 FNDC4 NRBP1 PIGV PSRC1 SLC22A3
Overall health rating 0.99 1 0 0.0 0.00 1.0e+00 NRBP1
Medication: Aspirin 6.19 7 1 3.0 0.99 2.6e-05 C19orf80 CORO6 EPOR OPRL1 PSRC1 SLC22A3 VEGFB
Hypertension (Self-reported) 2.34 5 3 9.1 1.00 1.3e-04 CBX1 CORO6 OPRL1 PIGV VEGFB
Illnesses of father: Heart disease 5.86 5 2 6.1 1.00 2.5e-05 EPOR OPRL1 PSRC1 SLC22A3 SMARCA4
Forced expiratory volume in 1-second (FEV1), predicted 1.60 1 0 0.0 0.00 1.0e+00 SMARCA4
Whole body fat-free mass 2.89 8 7 21.2 -0.88 2.9e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Leg fat-free mass (right) 2.53 8 5 15.2 -0.89 1.5e-03 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Arm fat percentage (left) 1.41 4 2 6.1 -0.44 5.6e-01 COL4A3BP CORO6 HPR POLK
Diabetes diagnosed by doctor 2.54 5 1 3.0 -0.25 6.8e-01 FNDC4 NRBP1 OPRL1 POLK VEGFB
Qualifications: nursing, teaching 0.93 1 0 0.0 0.00 1.0e+00 DOCK7
Medication for cholesterol 6.90 12 1 3.0 -0.98 9.6e-09 DOCK7 FNDC4 HPR NRBP1 OPRL1 PAFAH1B2 PIGV PSRC1 RGL3 SLC22A3 SZRD1 VEGFB
Back pain experienced in last month 1.47 1 0 0.0 0.00 1.0e+00 APOB
Asthma (self-reported) 1.75 3 0 0.0 0.00 1.0e+00 CARM1 SMARCA4 YIPF2
Medication: Aspirin 6.20 8 1 3.0 0.99 3.1e-06 C19orf80 CORO6 EPOR OPRL1 PSRC1 SLC22A3 SMARCA4 VEGFB
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.23 1 0 0.0 0.00 1.0e+00 OPRL1
Whole body water mass 2.87 8 6 18.2 -0.88 3.7e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Leg predicted mass (right) 2.56 8 5 15.2 -0.89 1.4e-03 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Arm fat mass (left) 1.94 4 2 6.1 -0.67 2.1e-01 COL4A3BP HPR POLK SLC22A3
Number of self-reported non-cancer illnesses 3.93 5 0 0.0 1.00 1.7e-04 CBX1 FNDC4 NRBP1 OPRL1 VEGFB
Medication: Blood pressure 2.39 4 1 3.0 0.99 5.9e-03 CBX1 OPRL1 PIGV VEGFB
Supplements: Fish oil (including cod liver oil) 0.84 1 0 0.0 0.00 1.0e+00 SLC22A3
High cholesterol (Self-reported) 46.37 29 25 75.8 0.98 7.2e-24 ABCA1 APOB BCAM C19orf80 CARM1 CBX1 COL4A3BP COX8A DOCK7 EPOR FNDC4 HPR ILF3 NRBP1 OPRL1 PAFAH1B2 PIGV POLK PSRC1 PVRL2 RASA3 RGL3 SLC22A3 SMARCA4 SZRD1 TOMM40 VEGFB YIPF2 ZNF259
Medication: Bendroflumethiazide 1.24 1 0 0.0 0.00 1.0e+00 PIGV
Medication: Lisinopril 1.64 1 0 0.0 0.00 1.0e+00 RASA3
Medication: Atorvastatin 18.68 19 11 33.3 0.99 6.4e-18 ABCA1 APOB BCAM C19orf80 COL4A3BP DOCK7 EPOR FNDC4 HPR NRBP1 OPRL1 PAFAH1B2 PSRC1 PVRL2 SLC22A3 SMARCA4 TOMM40 VEGFB ZNF259
Basal metabolic rate 2.79 8 6 18.2 -0.88 3.3e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Leg fat percentage (left) 1.34 4 2 6.1 -0.59 4.1e-01 BCAM COL4A3BP CORO6 POLK
Arm fat-free mass (left) 2.91 8 6 18.2 -0.88 4.1e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4
Diastolic blood pressure, automated reading 1.06 2 0 0.0 0.00 1.0e+00 C19orf80 PIGV
Vascular/heart problems diagnosed by doctor 2.91 6 3 9.1 -0.98 4.4e-04 CBX1 CORO6 NRBP1 OPRL1 PIGV VEGFB
Pain experienced in last month 1.73 1 0 0.0 0.00 1.0e+00 OPRL1
Heart attack/myocardial infarction (self-reported) 4.09 3 1 3.0 0.00 1.0e+00 C19orf80 PSRC1 SLC22A3
Heart disease (siblings) 4.57 4 1 3.0 0.99 1.4e-02 PSRC1 SLC22A3 SMARCA4 ZNF259
Impedance of whole body 1.97 6 5 15.2 0.81 5.0e-02 CBX1 COL4A3BP FNDC4 NRBP1 OPRL1 POLK
Leg fat mass (left) 1.97 6 2 6.1 -0.59 2.2e-01 BCAM COL4A3BP CORO6 HPR POLK SLC22A3
Arm predicted mass (left) 2.96 8 7 21.2 -0.89 2.3e-04 COL4A3BP EPOR FNDC4 NRBP1 POLK PSRC1 SLC22A3 SMARCA4

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 1 0.0286 1.49
GTEx Adipose Visceral Omentum 2 0.0982 1.53
GTEx Adrenal Gland 0 0.0000 1.46
GTEx Artery Aorta 3 0.1008 1.48
GTEx Artery Coronary 0 0.0000 1.46
GTEx Artery Tibial 4 0.1064 1.46
GTEx Brain Caudate basal ganglia 1 0.1087 1.34
GTEx Brain Cerebellar Hemisphere 2 0.1343 1.48
GTEx Brain Cerebellum 1 0.0505 1.47
GTEx Brain Cortex 0 0.0000 1.52
GTEx Brain Frontal Cortex BA9 1 0.1082 1.62
GTEx Brain Hippocampus 0 0.0000 1.48
GTEx Brain Hypothalamus 0 0.0000 1.38
GTEx Brain Nucleus accumbens basal ganglia 0 0.0000 1.53
GTEx Brain Putamen basal ganglia 0 0.0000 1.36
GTEx Breast Mammary Tissue 0 0.0000 1.45
GTEx Breast Mammary Tissue (Male) 0 0.0000 1.48
GTEx Breast Mammary Tissue (Female) 0 0.0000 1.47
GTEx Cells EBV-transformed lymphocytes 0 0.0000 1.48
GTEx Cells Transformed fibroblasts 6 0.1429 1.45
GTEx Colon Sigmoid 1 0.0684 1.45
GTEx Colon Transverse 1 0.0484 1.46
GTEx Esophagus Gastroesophageal Junction 0 0.0000 1.45
GTEx Esophagus Mucosa 6 0.1807 1.51
GTEx Esophagus Muscularis 5 0.1547 1.46
GTEx Heart Atrial Appendage 0 0.0000 1.52
GTEx Heart Left Ventricle 0 0.0000 1.43
GTEx Liver 2 0.2789 1.83
GTEx Lung 0 0.0000 1.45
GTEx Muscle Skeletal 1 0.0346 1.52
GTEx Nerve Tibial 3 0.0694 1.44
GTEx Ovary 1 0.1101 1.55
GTEx Pancreas 1 0.0613 1.42
GTEx Pituitary 0 0.0000 1.53
GTEx Prostate 0 0.0000 1.58
GTEx Skin Not Sun Exposed Suprapubic 3 0.1220 1.49
GTEx Skin Sun Exposed Lower leg 6 0.1648 1.57
GTEx Small Intestine Terminal Ileum 0 0.0000 1.49
GTEx Spleen 2 0.1417 1.56
GTEx Stomach 2 0.1376 1.55
GTEx Testis 3 0.0951 1.44
GTEx Thyroid 7 0.1750 1.52
GTEx Uterus 0 0.0000 1.40
GTEx Vagina 1 0.1575 1.57
GTEx Whole Blood 4 0.2007 1.59
METSIM Adipose 2 0.0434 1.41
NTR Blood 3 0.1249 1.46
ROSMAP Brain Pre-frontal Cortex 8 0.1822 1.54
YFS Blood 6 0.1299 1.43
CommonMind Brain Pre-frontal Cortex 10 0.1860 1.57
TCGA Breast Tumor 1 0.1304 1.41
TCGA Breast Normal 4 0.0951 1.40
TCGA Ovarian Tumor 2 0.0684 1.40
TCGA Prostate Tumor 2 0.0578 1.40