Hub : Genes

ESD

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0730	0.0240	3.8e-04	0.052	0.025	0.052	0.037	0.048	5.6e-07	3.9e-04	5.8e-07	2.5e-05	1.4e-06
2	GTEx	Artery Aorta	0.1790	0.0650	5.9e-03	-0.005	NA	0.015	NA	0.002	8.8e-01	NA	5.0e-02	NA	2.4e-01
3	GTEx	Artery Tibial	0.1211	0.0383	6.0e-04	0.096	NA	0.071	NA	0.083	6.0e-08	NA	3.0e-06	NA	4.9e-07
4	GTEx	Stomach	0.2230	0.0830	7.0e-03	0.015	NA	0.003	NA	0.014	6.1e-02	NA	2.1e-01	NA	6.7e-02
5	GTEx	Thyroid	0.1080	0.0410	5.0e-03	0.013	NA	0.043	NA	0.035	3.0e-02	NA	2.8e-04	NA	1.1e-03
6	YFS	Blood	0.0497	0.0121	2.2e-10	0.047	0.038	0.047	0.044	0.047	4.1e-15	1.7e-12	4.1e-15	2.6e-14	5.0e-15
7	TCGA	Brain Lower Grade Glioma	0.0801	0.0339	4.9e-06	0.035	0.050	0.039	NA	0.035	6.7e-05	2.0e-06	2.6e-05	NA	6.5e-05
8	TCGA	Uterine Corpus Endometrial Carcinoma	0.1290	0.0610	5.7e-03	0.006	0.029	0.009	NA	0.008	2.2e-01	5.2e-02	1.7e-01	NA	1.9e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.3	0.4	1.5	-0.2	1.2	-0.0	-0.5	0.6	-0.5	-1.0	0.1
Bipolar Disorder or Schizophrenia	0.1	0.2	0.6	0.5	0.8	0.4	0.4	0.2	-0.7	-0.1	0.2
Depressed Affect (Nagel 2018)	1.0	2.2	3.9	-1.7	-2.0	-1.6	-0.0	-1.4	1.7	-1.0	1.5
Depression (Nagel 2018)	0.1	0.1	0.3	-0.1	-0.3	-0.5	-0.3	-0.1	-0.0	-0.5	0.6
Intelligence (Savage-Jansen 2018)	0.7	2.1	5.5	1.7	1.8	1.3	-1.1	1.0	-2.3	1.0	-0.3
Neuroticism (Nagel 2018)	0.4	0.9	3.4	-0.4	-1.8	-0.3	1.4	-0.9	0.9	-0.3	-0.2
Schizophrenia (2018)	0.1	0.3	0.9	0.8	0.0	0.5	0.9	-0.1	-0.5	0.7	0.2
Schizophrenia vs Biploar Disorder	1.0	1.4	3.8	1.4	-0.0	1.2	1.0	1.2	-0.5	2.0	-1.0
Worry (Nagel 2018)	0.8	1.7	4.2	1.4	-0.4	1.5	1.6	1.0	-1.2	0.6	-2.0
Alzheimer’s Disease (in mother)	2.1	2.5	6.5	1.4	0.9	1.7	-0.4	1.4	-1.7	2.6	-1.6
Alzheimer’s Disease (in father)	0.8	0.9	4.6	-0.5	-2.1	0.3	-0.4	0.2	0.8	-0.6	-1.0
Alzheimer’s Disease (including proxy)	0.3	0.4	1.0	0.2	-0.2	0.8	-0.1	0.9	-0.1	1.0	-0.9
Crohns Disease (2017)	1.3	2.8	5.0	2.0	2.0	1.7	0.2	2.0	-2.2	1.3	-1.0
Irritable Bowel Disease (IBD)	0.6	1.5	5.5	0.7	2.3	0.7	-1.5	1.3	-1.2	0.2	-0.7
Ulcerative Colitis (UC)	0.7	1.3	6.9	-0.3	2.6	0.0	-1.8	0.1	-0.5	-0.1	-0.1
Major Depression (MDD)	1.3	1.6	4.7	0.9	-2.2	0.9	0.7	1.2	-1.0	0.7	-1.8
Reaction Time	0.1	0.2	0.8	0.3	-0.3	0.1	0.9	0.1	-0.7	-0.4	-0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.2	-0.1	0.1	-0.7	-0.6	-0.2	-0.3	0.2	1.5
Breast Cancer	0.1	0.2	0.8	-0.3	0.4	0.2	-0.3	0.9	0.7	-0.5	0.0
Ovarian Cancer	0.1	0.2	0.8	0.2	-0.9	0.3	0.1	0.1	-0.3	-0.4	-0.0
Prostate Cancer	0.5	0.7	3.6	0.2	0.7	0.2	-0.9	-1.9	-0.1	0.8	-0.0
Age at First Birth	0.4	0.6	1.4	-0.8	0.5	-1.1	-0.4	-0.6	-0.2	-1.0	1.2
Bipolar Disorder (2011)	1.9	1.9	6.2	1.6	0.8	1.6	0.4	0.4	-2.5	1.4	-0.7
Body Mass Index (BMI) (2010)	0.3	0.4	1.6	-0.2	-1.3	-0.0	-1.1	-0.3	-0.0	-0.2	0.3
Coronary Artery Disease (CAD)	1.0	1.2	6.5	-0.2	0.8	-0.2	2.5	1.5	0.0	-0.5	0.1
Crohns Disease (2012)	1.5	2.4	4.7	2.0	1.7	1.6	0.8	2.2	-1.8	0.7	-1.0
Mean Putamen Volume	1.0	1.1	2.1	1.2	0.3	1.2	-0.0	1.1	-1.5	1.3	-1.1
Fasting Glucose	0.8	1.0	2.4	-1.4	-1.4	-1.6	-0.4	-0.6	0.8	-0.7	0.4
HbA1C	0.3	0.3	1.1	0.2	-0.1	0.3	-0.9	1.0	0.5	0.3	-0.3
HDL Cholesterol	0.3	0.4	1.2	0.4	1.1	0.5	-0.6	0.3	-0.8	0.7	-0.5
LDL Cholesterol	0.4	0.6	1.3	-0.9	-0.9	-0.3	0.7	-1.1	0.6	-0.9	0.5
Lupus	0.4	0.6	2.0	0.2	0.9	0.3	1.3	0.2	-0.3	-0.2	-1.4
Neuroticism (2016)	0.2	0.4	1.2	0.0	-0.9	-0.3	0.3	-1.1	0.8	-0.2	-0.1
Primary Biliary Cirrhosis	0.3	0.5	1.8	0.7	-1.3	0.2	-0.5	0.5	-1.0	0.3	0.1
Rheumatoid Arthritis	0.8	1.1	4.1	1.5	-0.1	1.3	0.1	0.7	-0.6	2.0	-0.5
Schizophrenia (2014)	0.2	0.4	1.7	0.6	-0.1	0.5	1.3	0.7	-0.1	0.5	-0.5
Triglycerides	0.1	0.1	0.3	0.2	-0.4	0.1	0.6	0.0	-0.2	-0.2	0.3
Type 2 Diabetes (T2D) (2012)	1.0	1.1	4.0	1.2	0.9	0.8	2.0	1.3	-0.6	0.2	-0.2
Ulcerative Colitis	1.0	1.4	3.2	-1.3	0.8	-1.1	-1.8	-0.8	0.7	-1.0	1.6
Blood Eosinophil Count	0.2	1.2	8.0	-0.4	0.4	-0.1	-2.8	-0.8	-0.8	-0.4	0.3
Blood Platelet Count	0.2	2.6	7.9	1.5	2.8	1.9	1.3	1.6	-0.8	0.3	-1.4
Blood Red Count	0.2	1.5	5.1	1.0	1.7	1.0	-0.6	-0.3	-2.2	0.8	-0.9
Blood White Count	0.1	0.8	3.0	0.3	0.5	0.9	0.4	1.1	0.6	-0.1	-1.7
Heel T-Score	0.1	0.4	3.2	-0.0	0.2	-0.3	0.1	-0.3	-0.1	-1.8	-0.1
BMI	0.1	0.8	3.3	-0.9	-1.8	-0.1	-0.7	-0.6	1.0	0.3	-0.8
Height	0.2	3.0	8.1	0.3	2.8	0.4	-2.5	2.1	-0.7	-2.1	-0.0
Waist Hip Ratio (WHR)	0.1	0.5	2.4	0.7	1.1	0.4	0.3	0.1	-1.5	0.1	-0.2
Systolic Blood Pressure	0.2	1.2	2.8	-1.3	-0.6	-1.1	1.7	0.7	0.8	-1.6	0.4
Smoking Status	0.1	0.2	0.8	-0.4	-0.3	-0.2	-0.9	0.7	0.3	-0.1	-0.0
Allergy or Eczema	0.1	0.3	0.5	0.7	0.7	0.6	-0.1	-0.0	-0.5	0.4	-0.5
Cardiovascular Disease	0.5	1.8	5.6	1.1	0.6	0.8	0.9	2.4	-1.6	-0.6	-1.6
Hypothyroidism (self reported)	0.3	0.6	4.4	-0.4	-2.1	-0.2	-0.3	-0.3	-0.1	-0.2	0.3
Respiratory disease	1.4	3.1	4.5	2.1	-1.0	2.0	-1.4	1.8	-1.8	1.8	-1.8
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.7	-0.7	0.7	-0.4	-0.1	-0.3	1.3	-0.8	1.0
Lung FEV1/FVC ratio	0.7	3.7	10.4	-1.8	-0.3	-2.0	0.6	-3.2	1.3	-0.5	3.1
Lung FVC	0.1	0.5	0.9	-0.2	-1.0	-0.2	0.4	0.9	0.9	-0.6	-0.8
Neuroticism	0.4	0.9	2.7	-0.5	-1.5	-0.5	1.7	-0.1	1.0	-0.8	-0.6
Chronotype (morning person)	0.7	1.7	4.1	1.7	-0.3	1.8	1.3	-0.5	-2.0	0.4	-1.1
Hair Pigment	0.0	0.8	1.6	1.0	-0.7	0.9	-1.0	0.7	0.0	0.8	-1.3
Tanning	0.1	1.2	5.4	-0.8	-2.3	-0.5	0.6	0.6	1.0	-0.3	-1.3
Hand grip strength (left)	1.1	3.0	4.4	-1.9	1.1	-2.1	-0.7	-1.2	2.1	-2.1	2.0
Number of treatments/medications taken	3.5	6.3	12.2	2.9	0.6	3.3	-0.3	3.5	-2.2	1.8	-3.2
Average weekly spirits intake	1.6	2.0	6.0	-1.5	-0.7	-1.3	-0.9	-0.7	1.9	-2.5	0.6
Sensitivity / hurt feelings	0.3	0.5	2.0	0.5	-0.1	0.5	1.0	0.3	0.5	0.1	-1.4
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.6	-0.5	0.2	-0.7	-0.6	-0.5	0.6	-1.3	0.7
Hearing difficulty/problems: Yes	0.1	0.2	1.0	0.5	0.1	0.1	-0.2	-0.1	-1.0	-0.1	-0.7
Relative age of first facial hair	0.2	0.4	1.0	0.9	-0.8	0.6	1.0	0.4	-0.3	0.4	-0.5
Other serious medical condition/disability diagnosed by doctor	1.8	2.4	4.5	2.0	0.8	1.9	1.1	1.3	-2.1	1.6	-1.1
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.0	0.8	1.1	1.0	0.6	1.1	-0.3	-0.0	-1.7
Ever had hysterectomy (womb removed)	0.8	0.8	3.0	0.6	0.6	0.5	1.4	1.7	0.4	0.6	-0.6
Systolic blood pressure, automated reading	0.2	0.7	1.7	-0.7	-1.2	-0.3	1.0	0.7	0.3	-1.3	-0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.9	0.1	-0.7	0.3	-1.4	0.0	0.2	-0.4	-0.3
Angina	2.3	3.1	7.5	1.6	-0.8	1.9	1.3	2.7	-1.5	1.0	-2.3
Medication for hormone replacement therapy	1.3	1.5	4.2	-1.3	0.3	-0.9	2.0	-0.9	2.0	-0.5	0.3
Vitamin and mineral supplements	0.6	0.8	1.6	0.4	-1.2	0.7	0.9	0.6	-0.7	1.3	-0.9
Supplements: Zinc	1.0	1.0	6.1	-0.6	2.5	-0.4	-0.3	0.5	0.7	-0.8	0.2
Medication: Co-codamol	0.1	0.1	0.5	-0.2	-0.4	-0.1	-0.4	0.2	0.7	-0.1	0.2
Medication: Metformin	2.3	3.3	7.3	2.4	-0.6	2.7	-0.4	0.6	-2.0	1.6	-2.4
Diabetes (father)	0.1	0.1	0.4	0.1	-0.0	0.1	-0.0	-0.1	0.6	0.4	0.1
Diabetes (mother)	0.4	0.5	2.2	0.1	0.1	-0.2	-1.0	-1.5	-0.1	0.9	0.6
Severe depression (siblings)	0.6	0.7	1.8	-0.4	-1.3	-0.5	-1.3	-0.3	0.2	0.1	1.3
Pack years adult smoking proportion	0.5	0.7	2.7	0.4	-0.1	0.6	-1.6	1.1	-0.8	0.2	-0.7
Impedance of leg (right)	0.1	0.7	2.7	0.4	1.6	0.1	0.4	0.4	-1.4	-0.6	-0.1
Leg fat-free mass (left)	0.3	1.6	2.6	-1.6	-0.2	-1.3	-1.3	-1.2	1.6	-1.1	1.4
Trunk fat percentage	0.1	0.5	1.7	0.1	-1.1	0.5	-1.3	0.2	-1.0	-0.2	-0.4
Hand grip strength (right)	1.1	3.0	5.7	-1.9	0.9	-2.0	-0.3	-1.7	1.8	-2.0	2.4
Townsend deprivation index at recruitment	0.5	0.7	1.8	-0.7	-0.1	-0.5	-1.4	0.8	0.8	-0.7	-0.9
Current tobacco smoking	2.4	3.9	7.0	-2.5	-1.6	-2.1	-1.2	-1.7	2.6	-2.0	1.8
Average weekly fortified wine intake	0.4	0.5	3.8	0.3	0.0	0.1	-2.0	0.2	-0.1	-0.2	-0.3
Maternal smoking around birth	1.8	2.7	8.0	0.8	-2.8	1.6	-0.8	1.8	0.3	1.8	-1.7
Fed-up feelings	0.1	0.3	0.8	-0.5	0.2	-0.6	0.3	-0.6	0.5	-0.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.4	-0.4	-0.3	-0.2	-0.0	0.2	0.6	-0.4	-0.2
Relative age voice broke	1.6	2.4	3.8	1.9	-0.7	1.6	1.2	1.9	-1.6	1.8	-1.3
Taking other prescription medications	4.4	6.7	15.4	3.2	1.7	2.9	-0.8	3.9	-3.0	1.4	-2.3
Age when periods started (menarche)	0.2	0.4	1.4	0.7	-0.5	0.5	-0.3	0.5	-0.6	1.2	-0.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.3	0.2	-0.9	0.7	1.4	1.4	0.5	-0.1	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.0	1.0	-0.7	1.0	-0.1	-0.3	-0.7	0.8	-0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	5.5	-0.1	-0.2	-0.6	-2.3	-0.0	0.3	-0.7	0.2
Qualifications: CSEs or equivalent	0.5	0.7	3.6	-0.3	-0.8	0.1	0.3	-1.9	0.6	0.5	0.6
Serious illness, injury or assault to yourself	1.1	1.4	3.3	1.0	-0.1	1.1	-1.2	1.8	-1.3	1.4	-0.6
High blood pressure	0.6	1.7	3.9	1.2	-0.4	1.3	0.2	2.0	-1.9	0.4	-1.7
Hayfever, allergic rhinitis or eczema	0.5	1.1	1.9	1.4	1.3	1.3	0.4	-0.0	-1.1	1.1	-0.7
Multivitamins +/- minerals	0.6	0.7	1.5	-0.4	0.8	-0.8	-0.7	-0.8	0.5	-1.0	1.2
Stomach or abdominal pain in last month	0.4	0.5	1.2	-0.7	1.0	-0.6	0.3	1.1	1.0	-0.4	0.3
Supplements: Glucosamine	0.4	0.5	2.4	-0.3	-1.1	-0.1	-0.1	1.6	0.2	-0.5	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.4	-0.5	-1.2	-0.5	1.1	-0.4	0.2	-0.2	0.4
Medication: Atenolol	0.4	0.6	2.2	0.6	0.5	0.9	1.5	0.4	-0.4	0.1	-0.8
Medication: Levothyroxine sodium	1.7	2.8	15.6	-1.7	-4.0	-1.4	-0.1	-0.0	1.0	-1.0	0.7
Sitting height	0.6	4.4	11.2	-1.7	2.3	-1.8	-3.4	-0.7	1.4	-2.7	1.7
Chronic bronchitis/emphysema (father)	0.7	0.9	2.0	0.9	0.5	1.0	-0.5	1.3	-1.4	0.9	-0.4
High blood pressure (mother)	0.3	0.4	1.6	0.2	0.7	-0.3	-0.2	-1.3	-0.3	-0.7	0.8
Body mass index (BMI)	0.2	0.9	5.3	-0.5	-2.3	0.1	-1.1	-0.6	0.4	0.2	-0.1
Impedance of leg (left)	0.3	1.5	5.1	1.3	1.4	0.9	0.5	1.3	-2.3	0.3	-0.8
Leg predicted mass (left)	0.3	1.7	2.7	-1.6	-0.3	-1.4	-1.2	-1.2	1.6	-1.1	1.4
Trunk fat mass	0.1	0.5	2.6	-0.4	-1.0	0.0	-1.6	-0.1	-0.3	-0.6	0.1
Waist circumference	0.1	0.5	2.5	-0.2	-1.6	0.4	-1.0	-0.1	-0.3	0.2	-0.6
Number of incorrect matches in round	0.6	0.9	4.0	0.3	-0.9	0.6	0.7	-0.1	-0.8	1.0	-2.0
Past tobacco smoking	0.1	0.1	0.5	0.1	-0.3	0.3	-0.7	-0.3	0.4	0.4	0.3
Alcohol usually taken with meals	0.6	1.0	4.7	-0.5	0.1	-0.6	2.2	-1.4	0.5	-0.2	0.3
Nervous feelings	0.2	0.4	1.3	0.2	-0.7	0.4	1.1	-0.4	-0.1	-0.2	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.5	-0.4	-0.2	-0.5	-1.2	0.1	0.3	-0.6	0.3
Hearing difficulty/problems with background noise	0.4	0.6	2.3	0.5	1.5	0.3	-0.1	0.8	-1.0	-0.5	-0.8
Hair/balding pattern: Pattern 2	0.5	0.7	4.0	0.3	2.0	-0.0	0.4	-1.0	-0.4	-0.3	0.2
Had menopause	1.1	1.4	4.2	1.4	0.7	1.2	0.5	0.8	-2.0	1.1	-0.8
Had other major operations	0.8	1.0	2.7	-1.2	-0.4	-1.0	-1.6	-0.1	1.3	-1.0	0.1
Forced vital capacity (FVC)	0.1	0.4	1.0	-0.1	1.0	-0.2	-0.9	0.7	0.5	-0.6	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.3	0.9	1.0	0.0	0.8	-0.6	-0.1	-0.6	0.6	-0.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	3.7	-0.9	1.6	-1.1	0.1	-0.8	0.4	-1.9	1.1
Qualifications: None of the above	0.3	0.7	2.5	-0.0	-1.6	0.1	0.5	1.3	-0.4	-0.7	-0.9
Financial difficulties in last 2 years	0.0	0.1	0.2	-0.1	0.0	-0.2	0.4	-0.0	0.4	-0.0	-0.2
Mouth/teeth dental problems	0.6	0.9	1.8	-1.3	0.2	-1.2	-0.5	-1.3	1.0	-0.8	1.0
Heart attack	1.0	1.2	2.6	1.3	-0.1	1.5	0.2	1.3	-1.6	1.0	-0.8
Allergy	0.2	0.5	1.2	-1.1	-0.1	-1.0	0.3	-0.3	1.0	-0.8	0.4
Pain all over the body in last month	0.6	0.6	3.4	-0.1	1.8	0.0	0.2	-0.2	-0.5	1.1	0.5
Diabetes (self-reported)	0.3	0.5	1.4	0.8	0.6	1.2	0.3	0.7	-0.5	0.6	-0.7
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	-0.1	-0.3	-0.5	-1.5	-0.5	0.3	-0.6	0.6
Medication: Ramipril	0.9	1.2	4.2	0.7	0.4	1.1	2.0	0.9	-1.1	0.5	-1.2
Medication: Simvastatin	1.6	2.4	5.3	1.7	0.6	1.9	1.1	2.3	-1.0	0.9	-2.0
Fluid intelligence score	0.2	0.5	1.5	0.1	0.6	-0.4	-0.3	-1.1	-0.6	0.3	1.2
Illnesses of siblings	0.4	0.5	2.9	0.2	1.7	-0.3	0.8	0.2	-0.2	-0.6	-0.3
Neuroticism score	0.4	0.8	2.2	-0.7	-1.0	-0.6	1.5	-0.4	1.4	-0.5	0.0
Weight	0.2	0.9	2.4	-1.2	-0.6	-0.7	-1.6	-0.7	0.7	-1.1	0.7
Impedance of arm (right)	0.4	1.8	4.6	1.7	1.7	1.3	-0.2	1.2	-2.1	0.8	-0.8
Arm fat percentage (right)	0.2	0.9	3.6	0.2	-1.9	0.7	-1.6	-0.2	-0.5	0.5	-0.5
Trunk fat-free mass	0.3	1.9	3.6	-1.9	0.2	-1.6	-1.2	-0.8	1.8	-1.6	1.2
Hip circumference	0.1	0.6	2.5	-0.7	-1.6	-0.0	-1.1	-0.3	0.5	-0.2	-0.1
Time employed in main current job	0.8	1.0	3.2	0.7	-0.4	1.3	-0.3	1.0	-0.3	1.0	-1.8
Alcohol intake versus 10 years previously	1.8	2.7	5.2	-2.3	-1.2	-2.1	-0.0	-1.6	1.8	-1.5	1.7
Father’s age at death	0.3	0.4	2.0	0.4	-1.4	0.5	0.3	-0.3	-0.2	0.7	-0.2
Worrier / anxious feelings	1.2	2.3	9.4	-1.2	-3.1	-1.0	1.4	-1.8	1.2	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	4.0	-0.0	1.4	-0.2	2.0	0.2	-0.2	0.1	1.1
Falls in the last year	0.6	0.8	2.8	-0.3	1.5	-0.3	-1.7	-1.0	0.2	-0.2	0.2
Hair/balding pattern: Pattern 3	0.5	0.7	1.7	-1.2	-1.3	-1.0	-0.2	-0.6	0.8	0.2	0.5
Number of live births	0.3	0.5	2.1	0.1	0.1	0.2	-1.4	1.1	-0.7	0.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.0	-0.7	0.7	-0.9	-0.5	-0.4	0.9	-0.7	1.0
Pulse rate	0.6	1.1	4.4	-0.5	1.6	-0.5	-2.1	-0.3	0.3	-0.8	0.2
Happiness	0.6	0.8	1.8	-0.9	-0.9	-0.9	0.0	-0.5	0.9	-1.0	1.3
Noisy workplace	0.8	1.0	4.3	-0.3	0.3	0.0	-1.8	-0.1	0.3	-2.1	-0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	5.1	0.6	2.3	0.2	0.1	0.1	-0.1	0.3	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	1.3	-0.7	1.3	0.3	0.8	-0.9	0.6	-1.0
Mouth/teeth dental problems: Dentures	1.4	2.4	7.4	1.6	-0.2	1.9	-0.2	2.7	-1.8	0.8	-1.1
Asthma	0.3	0.6	1.5	0.6	-1.0	0.6	-1.2	0.8	-0.6	0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	4.7	-2.0	-0.8	-1.9	-2.2	-1.8	1.9	-1.6	1.3
Medication: Cholesterol lowering	0.2	0.3	2.0	0.0	-0.0	-0.0	1.4	0.5	0.1	-0.6	-0.1
Depression (self-reported)	0.3	0.4	1.9	-0.1	-0.5	-0.2	-0.5	0.7	0.3	-0.6	-1.4
Medication: Lansoprazole	4.2	4.8	9.4	2.8	0.9	2.8	-0.6	2.6	-3.1	1.3	-1.9
Prospective memory result	1.3	1.6	4.4	-1.7	-1.3	-1.1	0.2	-0.3	2.1	-1.3	0.6
Lung cancer (father)	0.5	0.6	1.7	0.2	0.3	0.2	-0.7	1.2	-0.0	-0.8	-1.3
Illnesses of mother	0.5	0.6	1.4	-0.9	-1.2	-0.7	1.1	0.0	0.7	-0.7	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.7	-1.3	0.4	-1.6	-0.7	-0.6	1.6	-1.3	1.6
Pulse wave Arterial Stiffness index	1.6	1.9	5.7	-1.1	1.2	-0.8	2.4	-2.0	0.7	-1.4	-0.0
Impedance of arm (left)	0.2	0.9	3.9	0.8	2.0	0.5	-0.1	1.0	-1.2	-0.2	-0.3
Arm fat mass (right)	0.1	0.5	2.2	-0.2	-1.4	0.4	-1.5	-0.0	-0.1	0.2	-0.2
Trunk predicted mass	0.3	1.9	3.5	-1.9	0.3	-1.6	-1.1	-0.8	1.8	-1.6	1.3
Standing height	0.4	3.7	10.6	-1.4	3.3	-1.7	-1.6	-0.3	0.7	-2.7	1.8
Length of working week for main job	1.8	2.0	5.0	-1.8	-1.5	-1.5	1.2	-1.0	2.2	-0.7	0.6
Exposure to tobacco smoke at home	0.2	0.2	0.5	0.3	-0.7	0.2	-0.5	0.7	0.0	0.5	0.2
Breastfed as a baby	0.3	0.3	1.6	-0.4	0.1	-0.4	0.5	-1.2	0.4	-0.4	0.4
Tense / ‘highly strung’	0.3	0.5	1.5	0.3	0.0	0.4	1.2	0.5	0.1	0.9	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.7	-0.3	-0.0	-0.2	-0.6	0.5	0.0	-0.4	-0.9
Hair/balding pattern: Pattern 4	1.6	3.8	8.2	2.8	0.9	2.9	-0.5	1.1	-1.7	2.2	-2.0
Birth weight of first child	0.1	0.3	0.9	-0.5	0.3	0.2	-0.4	0.3	-0.1	0.9	-0.9
Peak expiratory flow (PEF)	0.1	0.3	1.3	-0.3	-0.5	-0.4	-0.4	-1.1	0.5	-0.5	0.3
Pulse wave reflection index	1.6	2.0	5.9	-1.6	-0.8	-1.1	2.4	-1.8	1.2	-0.9	0.7
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	0.3	-0.4	0.0	-0.5	1.0	-0.3	-0.9	-0.5
Loud music exposure frequency	0.5	0.5	1.6	0.6	0.6	0.7	-1.3	0.3	-0.9	0.6	-0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.2	-0.1	1.1	-0.2	-0.4	-0.2	0.0	0.9	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.7	0.4	0.9	-0.1	0.3	0.4	-0.1	0.2	-0.0
Blood clot in the leg (DVT)	1.6	2.0	3.3	-1.8	-1.5	-1.7	0.3	-1.0	1.7	-1.0	1.8
Medication: Paracetamol	0.7	1.1	3.3	0.9	0.7	1.0	-1.2	1.0	0.1	0.6	-1.8
Headache pain in last month	0.1	0.1	0.6	0.3	-0.2	0.2	0.1	0.0	-0.0	0.8	-0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.5	-0.5	0.2	-0.3	-1.9	-1.2	0.4	0.7	0.7
Glaucoma (self-reported)	1.8	2.1	5.4	1.8	1.5	1.8	0.3	0.7	-2.3	0.7	-1.2
Gout (self-reported)	1.8	2.5	4.8	1.6	-0.4	1.8	2.0	2.2	-0.7	0.8	-2.0
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	4.6	-0.9	-2.1	-0.9	-0.1	0.1	0.4	-0.9	0.7
Medication: Amlodipine	0.7	1.0	1.8	1.0	-0.1	1.3	1.3	0.7	-0.9	1.2	-1.0
Medication: Ventolin 100micrograms inhaler	0.6	0.7	3.5	0.4	-0.5	0.6	-1.9	-0.1	-0.7	1.1	0.2
Birth weight	1.3	2.8	5.6	1.4	-0.1	1.6	2.0	2.2	-0.9	1.7	-2.4
Chronic bronchitis/emphysema (mother)	1.3	1.5	3.4	1.2	-0.3	1.7	0.3	1.9	-0.9	0.6	-1.8
High blood pressure (siblings)	0.3	0.4	1.3	0.1	-0.7	0.1	-1.1	-0.8	0.0	0.7	0.6
Forced vital capacity (FVC), Best measure	0.3	1.3	2.5	-1.1	1.0	-1.3	-0.8	0.2	1.4	-1.6	1.1
Body fat percentage	0.2	0.6	2.2	0.1	-1.5	0.5	-1.3	0.1	-0.8	0.0	-0.4
Leg fat percentage (right)	0.1	0.5	2.7	-0.2	-1.6	0.1	-1.0	-0.2	-0.5	-0.5	-0.2
Arm fat-free mass (right)	0.4	1.9	3.5	-1.9	0.1	-1.6	-0.9	-1.1	1.7	-1.5	1.4
Exposure to tobacco smoke outside home	1.8	2.4	6.7	-1.2	-2.6	-1.1	-1.1	-1.1	1.2	-0.5	2.3
Comparative body size at age 10	0.1	0.3	1.3	-0.5	-1.1	0.2	-0.6	-0.5	0.6	-0.3	0.1
Number of full brothers	0.5	0.7	1.9	0.6	-0.5	1.2	-0.4	0.4	-0.5	1.4	-0.9
Worry too long after embarrassment	0.6	1.1	6.8	0.7	0.0	0.7	2.6	0.4	0.0	0.4	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.0	0.3	1.1	0.1	-1.4	-0.4	-0.0	-0.2	-0.8
Wheeze or whistling in the chest in last year	0.8	1.4	3.8	1.3	-0.2	1.3	-0.6	1.2	-1.4	1.9	-0.7
Number of children fathered	0.3	0.4	1.0	0.3	0.1	0.2	-0.6	1.0	-0.6	-1.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	5.9	-0.2	0.5	-0.3	2.4	0.3	-0.2	-1.0	-0.3
Age at first live birth	0.4	0.8	2.2	0.4	1.5	-0.0	1.0	-0.5	-1.3	-0.3	0.9
Pulse wave peak to peak time	1.5	1.8	6.1	1.0	-1.1	0.6	-2.5	1.9	-0.7	1.1	0.1
Health satisfaction	0.1	0.1	0.3	0.2	-0.1	0.2	-0.6	-0.1	0.0	0.3	0.2
Shortness of breath walking on level ground	3.0	3.6	6.0	2.2	0.6	2.4	-0.7	2.4	-2.0	1.7	-2.2
Qualifications: College or University degree	0.9	2.8	13.4	1.4	3.7	0.9	0.2	1.8	-1.0	1.3	-0.5
Eye problems/disorders: None of the above	0.7	0.8	2.7	-0.6	-1.6	-0.7	-0.5	0.6	1.0	0.9	0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.2	0.6	-0.6	0.6	1.1	0.2	0.0	-0.2	-1.0
Emphysema/chronic bronchitis	4.1	4.6	9.5	2.8	0.4	2.7	-0.1	1.5	-2.7	3.1	-1.6
Medication for pain relief, constipation, heartburn	1.6	2.8	8.5	-1.3	-0.8	-1.8	1.4	-2.3	0.6	-0.3	2.9
Neck or shoulder pain in last month	0.4	0.5	2.5	0.1	-1.6	-0.1	0.2	-0.1	0.8	-0.8	-0.7
Medication: Blood pressure	0.4	0.7	1.6	0.3	-1.3	0.7	1.2	0.9	-0.5	0.1	-1.1
Angina (self-reported)	3.4	4.4	9.5	2.2	-0.7	2.5	0.9	3.1	-2.0	1.4	-2.8
Migraine (self-reported)	0.3	0.3	1.2	0.7	0.3	0.3	-0.6	0.3	-0.5	1.1	-0.1
Medication: Ibuprofen	2.6	3.1	5.1	-2.2	-0.9	-2.3	-0.9	-1.4	2.1	-1.9	1.8
Medication: Allopurinol	1.4	1.9	5.4	1.3	-0.0	1.4	2.3	1.9	-0.5	1.0	-1.2
Medication: Omeprazole	0.7	0.9	4.6	-0.8	-2.2	-0.2	-0.5	0.6	0.6	-0.5	-0.5
Medication: Seretide 50 evohaler	0.1	0.1	0.6	0.2	0.2	0.3	0.8	0.2	0.2	0.4	-0.3
Mean time to correctly identify matches	0.2	0.3	1.1	0.1	-0.3	-0.1	0.6	0.3	-0.7	-1.0	-0.8
Heart disease (mother)	0.7	0.8	2.3	-0.5	-0.1	-0.7	-1.2	-1.3	0.3	-1.5	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.7	1.0	0.1	1.3	0.6	1.0	-0.4	0.3	-0.8
Whole body fat mass	0.1	0.5	2.0	-0.3	-1.2	0.2	-1.4	0.0	-0.3	-0.4	-0.1
Leg fat mass (right)	0.1	0.5	1.9	-0.6	-1.4	-0.1	-1.1	-0.2	0.1	-0.4	0.1
Arm predicted mass (right)	0.3	1.7	3.3	-1.8	0.2	-1.5	-0.8	-0.8	1.6	-1.3	1.4
Pulse rate, automated reading	0.3	0.8	3.6	0.5	-0.0	0.6	-1.9	1.0	-0.6	0.9	-0.3
Alcohol intake frequency.	0.2	0.5	1.3	0.7	-0.3	1.0	-0.2	-0.1	0.2	1.1	-1.0
Comparative height size at age 10	0.2	1.0	5.0	-0.2	2.2	-0.0	-0.8	0.6	0.3	-1.4	0.5
Number of full sisters	0.4	0.5	1.6	-0.7	-0.5	-0.7	-0.7	-1.3	0.5	-0.4	0.7
Suffer from ‘nerves’	0.3	0.5	1.5	0.6	0.0	0.3	1.2	0.3	-0.5	-0.6	-1.1
Overall health rating	0.7	1.5	3.3	1.4	0.0	1.8	0.0	1.6	-0.8	1.2	-1.6
Chest pain or discomfort	2.0	2.8	4.8	2.1	1.0	2.2	-0.7	1.6	-1.3	1.8	-2.1
Had major operations	1.0	1.2	2.1	1.2	-0.6	0.9	1.5	0.8	-1.3	1.4	-0.9
Age at last live birth	0.3	0.5	2.4	0.6	1.6	0.1	-0.2	-0.0	-0.9	-0.1	0.2
Family relationship satisfaction	0.3	0.4	1.0	0.6	0.3	0.3	-0.9	-0.2	-0.9	0.5	1.0
Leg pain on walking	0.8	1.0	2.9	-0.9	0.4	-0.9	0.8	-0.8	1.7	-1.3	0.9
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.6	6.3	-1.8	-0.5	-1.6	-1.0	-1.5	2.5	-2.2	0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.8	-0.0	0.3	0.4	0.2	-0.9	0.6	0.6	0.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.2	-0.3	1.8	-0.5	0.5	0.3	-0.0	-0.5	-0.6
Medication: Aspirin	4.1	5.4	14.8	2.2	1.4	2.5	0.2	3.8	-2.2	0.4	-3.2
Supplements: Vitamin C	0.7	0.9	2.0	-0.7	1.2	-0.8	-0.5	0.3	1.1	-1.4	0.8
Knee pain experienced in last month	0.3	0.5	1.9	0.0	-1.4	0.2	1.1	-0.6	-0.0	0.1	-0.6
Hypertension (Self-reported)	0.6	1.5	3.2	1.1	-0.4	1.2	0.3	1.8	-1.8	0.3	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.6	3.0	4.0	1.9	-1.8	2.0	-1.5	1.5	-1.7	1.6	-1.9
Illnesses of father: Heart disease	1.9	2.6	4.8	2.2	1.7	1.9	1.9	1.0	-1.6	0.4	-1.6
Illnesses of siblings: Diabetes	1.0	1.2	4.5	1.0	-0.1	1.5	-0.7	-0.1	-0.6	2.1	-0.8
Smoking status: Previous	1.4	2.0	4.0	1.6	0.6	1.5	0.6	1.4	-2.0	0.9	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.9	-1.4	0.6	-1.1	-1.4	-0.9	1.3	-1.2	1.7
Whole body fat-free mass	0.3	1.5	2.9	-1.7	0.1	-1.4	-1.1	-0.8	1.6	-1.2	1.2
Leg fat-free mass (right)	0.2	0.9	1.3	-1.1	-0.3	-0.9	-1.1	-0.8	1.1	-0.5	1.1
Arm fat percentage (left)	0.2	0.6	2.9	-0.2	-1.7	0.3	-1.4	-0.4	-0.0	0.1	-0.2
Average weekly red wine intake	1.2	1.7	4.0	-0.6	-0.6	-1.3	1.4	-1.9	1.0	-2.0	0.7
Handedness (chirality/laterality): Left-handed	1.4	1.6	3.6	-1.7	1.2	-1.3	-0.5	-0.9	1.3	-1.9	0.6
Mood swings	1.8	3.3	4.7	-2.1	-1.7	-2.0	1.2	-2.2	2.1	-1.1	1.8
Loneliness, isolation	0.7	1.0	1.8	-0.9	-1.1	-1.1	-0.2	-1.4	1.0	-0.8	1.1
Long-standing illness, disability or infirmity	2.6	4.0	7.1	2.3	-0.8	2.7	-0.2	2.2	-1.9	2.3	-2.3
Ever had bowel cancer screening	0.5	0.6	1.4	0.9	0.1	1.0	0.6	0.6	-1.2	0.3	-0.7
Diabetes diagnosed by doctor	0.4	0.6	1.8	1.0	0.2	1.3	0.2	0.7	-0.6	0.9	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	0.7	-0.8	0.7	0.5	0.1	-0.4	0.4	-0.4
Friendships satisfaction	0.3	0.4	1.8	-0.0	0.3	-0.3	-1.1	0.1	-0.1	-1.4	0.3
Qualifications: nursing, teaching	0.2	0.3	1.0	1.0	0.7	0.7	-0.1	-0.2	-0.6	0.5	0.1
Commuting to job workplace: Walk	1.3	1.4	3.6	-0.8	0.8	-1.2	1.9	-1.2	0.3	-1.7	0.3
Eye problems/disorders: Cataract	1.2	1.4	7.5	0.9	2.7	0.8	0.8	-0.0	-1.3	-0.2	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	2.3	0.7	-1.3	0.6	0.0	-0.2	-0.6	1.5	-0.8
Medication for cholesterol	3.2	4.9	11.1	-2.3	-0.3	-2.9	-1.9	-2.3	1.7	-1.6	3.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.7	0.8	0.3	1.1	-0.4	2.2	-1.1	0.5	-2.0
Back pain experienced in last month	0.7	1.1	3.3	-0.9	-1.8	-0.6	0.3	0.7	1.8	-0.5	-0.4
Mineral and other dietary supplements	0.2	0.3	0.7	0.3	-0.6	0.4	-0.7	0.2	-0.1	0.8	-0.5
Breast cancer (self-reported)	0.7	0.8	2.6	-0.8	-0.7	-1.2	-0.1	-1.6	0.9	-0.5	0.7
Asthma (self-reported)	0.5	0.9	2.1	1.0	-0.7	1.0	-1.4	0.9	-1.1	0.7	-0.6
Osteoporosis (self-reported)	0.5	0.7	2.2	-0.7	-0.4	-0.9	1.1	-0.6	0.1	-0.4	1.5
Osteoarthritis (self-reported)	1.5	2.0	4.6	-1.3	-2.2	-1.5	-0.4	-1.0	1.0	-2.0	1.1
Medication: Aspirin	4.2	5.5	14.2	2.4	1.3	2.7	-0.1	3.8	-2.4	0.7	-3.0
Medication: Gliclazide	0.9	1.0	2.5	1.5	-0.4	1.6	-0.3	-0.6	-0.8	1.3	-0.8
Illnesses of father: None of the above (group 1)	1.2	1.5	3.3	-1.4	-1.3	-1.8	-1.2	-1.0	0.4	-1.1	1.2
Smoking status: Current	2.7	4.3	7.4	-2.7	-1.2	-2.4	-0.8	-1.9	2.7	-1.9	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.0	-0.7	-0.0	-1.0	-0.9	-0.6	0.7	-0.8	0.9
Whole body water mass	0.3	1.4	2.7	-1.6	-0.0	-1.4	-1.1	-0.8	1.6	-1.1	1.2
Leg predicted mass (right)	0.2	0.8	1.5	-1.1	-0.4	-0.9	-1.0	-0.7	1.2	-0.5	1.0
Arm fat mass (left)	0.2	0.6	2.6	-0.5	-1.4	0.1	-1.6	-0.4	0.1	-0.1	-0.1
Number of self-reported non-cancer illnesses	1.9	3.2	4.9	2.2	-0.9	2.2	-0.2	2.2	-2.0	1.4	-2.1
Average weekly champagne plus white wine intake	0.2	0.3	1.4	0.2	1.2	-0.0	0.3	0.3	0.6	0.2	-0.4
Miserableness	1.7	2.9	6.8	-2.1	-1.3	-1.9	-0.5	-1.5	2.6	-1.6	1.1
Guilty feelings	1.9	2.9	7.5	-2.0	-1.5	-1.7	0.4	-2.2	2.7	-0.9	0.9
Wears glasses or contact lenses	0.9	1.1	1.9	1.2	-0.1	1.4	-0.1	0.5	-1.4	1.2	-1.2
Ever taken oral contraceptive pill	2.2	2.4	4.0	1.5	0.6	1.6	-2.0	1.4	-1.8	2.0	-1.1
Hearing aid user	0.7	0.8	3.2	1.0	1.8	1.0	0.2	0.3	-1.0	0.3	-0.3
Mother’s age at death	0.7	0.9	2.3	-0.2	-1.5	-0.5	1.5	-0.9	0.9	0.7	0.4
Financial situation satisfaction	1.1	1.4	3.1	-1.4	-0.0	-1.3	0.4	-0.1	1.8	-1.7	1.1
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.2	0.8	1.1	0.7	-0.2	0.6	-0.3	-0.6	-0.3
Commuting to job workplace: Public transport	1.1	1.4	2.4	1.4	0.9	1.0	1.3	1.3	-1.6	0.2	-1.1
Eye problems/disorders: Glaucoma	0.2	0.3	0.7	0.2	0.4	0.6	-0.9	-0.2	-0.6	-0.3	-0.5
Medication: Blood pressure	2.5	4.7	8.7	2.3	-0.8	2.6	1.3	2.6	-2.5	1.3	-3.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.5	0.8	1.2	1.2	-0.0	-0.0	-0.4	0.6	-0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.9	-0.5	0.9	-0.6	-0.0	-0.6	-0.3	-0.9	0.7
High cholesterol (Self-reported)	2.4	4.3	9.2	2.4	1.5	2.3	1.7	3.0	-2.0	0.9	-2.1
Medication: Bendroflumethiazide	0.5	0.7	4.6	-0.7	-2.1	-0.2	-0.2	0.1	0.2	-0.6	-0.3
Medication: Paracetamol	0.7	1.1	2.6	1.1	1.2	1.1	-0.5	1.3	-0.3	0.9	-1.6
Medication: Lisinopril	1.1	1.4	2.1	1.4	-0.3	1.4	1.2	0.7	-1.4	1.2	-1.4
Medication: Atorvastatin	0.1	0.2	0.5	0.1	0.5	0.4	-0.7	-0.1	-0.5	-0.4	-0.1
Illnesses of father: High blood pressure	0.4	0.5	1.4	-0.5	0.1	-0.1	-0.5	-1.0	1.1	0.2	1.2
Alcohol drinker status: Never	0.4	0.5	1.3	-0.1	-0.6	-0.1	-1.1	0.6	0.6	0.7	-1.1
Ever smoked	0.5	0.9	2.1	-1.3	0.2	-1.4	0.8	-0.2	1.1	-1.3	0.4
Basal metabolic rate	0.3	1.6	2.8	-1.7	-0.2	-1.4	-1.3	-0.9	1.6	-1.2	1.2
Leg fat percentage (left)	0.2	0.8	3.9	0.2	-2.0	0.6	-1.0	0.1	-0.9	0.1	-0.7
Arm fat-free mass (left)	0.2	0.8	1.6	-1.3	-0.1	-1.0	-0.9	-0.6	1.1	-0.8	0.8
Number of operations (self-reported)	0.6	0.9	2.6	0.8	-0.8	0.6	1.5	0.7	-0.7	0.1	-1.6
Average weekly beer plus cider intake	0.2	0.2	0.5	-0.7	-0.4	0.0	0.2	0.6	0.7	-0.4	-0.5
Irritability	0.7	1.1	6.0	0.1	-1.2	0.2	2.4	-0.4	0.8	0.0	-0.9
Risk taking	0.2	0.3	0.7	-0.4	-0.5	-0.7	-0.8	-0.8	-0.2	-0.1	0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.1	0.3	-0.7	0.3	-0.2	0.9	-0.2	-1.0	-1.0
Fractured/broken bones in last 5 years	0.6	0.8	2.2	0.1	-0.9	0.3	-1.5	1.3	-0.5	-0.1	-1.2
Age started oral contraceptive pill	0.6	0.7	1.6	0.5	1.2	0.4	0.8	0.1	-1.1	0.6	-1.2
Diastolic blood pressure, automated reading	1.4	4.4	9.2	-3.0	-1.6	-2.6	-1.6	-1.5	2.0	-2.0	1.9
Ever depressed for a whole week	0.6	0.7	1.5	-0.3	0.9	-0.1	1.2	1.0	0.9	-0.7	-0.9
Unable to work because of sickness or disability	0.8	1.1	4.5	-0.7	1.4	-0.2	-2.1	-0.3	0.7	-0.9	0.5
Commuting to job workplace: Cycle	1.5	1.8	4.7	1.6	-0.5	1.4	0.3	1.3	-0.8	1.5	-2.2
Myopia	0.4	0.6	2.0	-0.1	-0.1	0.5	-1.4	0.1	0.6	1.4	-0.4
Vascular/heart problems diagnosed by doctor	1.0	2.7	5.4	-1.5	0.7	-1.7	-0.6	-2.3	2.2	-0.4	2.3
Cholesterol lowering medication	10.1	14.8	27.1	4.7	1.5	5.2	0.0	4.7	-3.6	2.9	-4.9
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	6.2	-0.9	-2.5	-0.3	-0.9	0.3	0.7	-0.6	-0.2
Pain experienced in last month	0.8	1.3	3.8	1.5	0.6	1.3	0.2	1.3	-1.9	0.4	-0.6
Supplements: Calcium	0.5	0.5	1.0	-0.9	-0.2	-0.8	0.4	-0.5	0.8	-0.7	1.0
Basal cell carcinoma (self-reported)	0.6	0.7	1.4	0.8	1.1	0.7	-0.3	1.0	-0.8	-0.2	-1.2
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.2	1.5	-0.2	1.6	0.2	1.4	-1.8	1.2	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	2.7	-1.6	-1.7	-1.4	0.6	-0.7	1.5	-0.6	1.3
Heart disease (siblings)	0.3	0.3	1.4	0.0	0.4	0.7	0.2	0.5	0.3	0.5	-1.2
Alcohol drinker status: Previous	1.1	1.3	3.9	0.8	-0.9	1.2	-0.5	1.6	-0.5	0.6	-2.0
Pack years of smoking	0.5	0.8	1.7	0.6	-0.5	0.7	-1.3	1.3	-0.9	0.4	-1.0
Impedance of whole body	0.2	1.1	3.7	1.0	1.9	0.6	-0.0	0.7	-1.8	-0.2	-0.3
Leg fat mass (left)	0.1	0.5	2.4	-0.3	-1.6	0.2	-1.1	-0.1	-0.1	-0.1	-0.2
Arm predicted mass (left)	0.1	0.7	1.5	-1.1	0.4	-0.8	-1.2	-0.5	0.9	-0.7	0.8