Hub : Traits :

Worrier / anxious feelings

638 significantly associated models · 119 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 3 49598064 51234774 6 2 1.8e-10 5.2e-08 5.8e-01 99 CYB561D2 SEMA3B-AS1
2 3 51616334 54077726 12 1 1.2e-13 1.3e-11 1.2e-01 95 ITIH4-AS1
3 3 84317575 86808226 1 1 7.1e-10 3.6e-16 6.2e-08 56 CADM2
4 3 135173458 137261517 4 1 2.9e-10 1.6e-10 6.1e-02 91 RP11-85F14.5
5 5 101762909 103244640 1 1 1.5e-07 2.1e-08 5.0e-02 88 PPIP5K2
6 7 126529931 128425768 3 2 4.8e-09 2.3e-10 6.7e-02 92 SND1
7 9 97520168 98975128 1 1 4.0e-07 2.9e-08 2.4e-02 83 PTCH1
8 10 103527782 105694301 10 2 1.6e-12 1.1e-11 2.4e-01 97 ACTR1A CYP17A1-AS1
9 11 56666189 58178587 3 1 7.7e-09 5.8e-08 8.9e-01 100 ZDHHC5
10 11 94825532 96261289 2 1 1.6e-08 6.3e-08 2.2e-01 95 AP001877.1
11 11 133079948 134525648 1 1 9.2e-09 3.0e-08 7.9e-02 90 IGSF9B
12 12 109231851 110605559 1 1 8.1e-08 1.7e-07 2.1e-01 94 KCTD10
13 14 74424938 76210831 5 2 2.7e-11 3.0e-10 1.0e+00 100 AREL1 MLH3
14 16 29580611 31758245 5 2 6.9e-08 4.2e-08 3.2e-01 97 HSD3B7 YPEL3
15 17 42607368 45796313 20 1 5.4e-09 3.1e-08 8.6e-01 100 MAPT
16 18 52209411 54028036 1 1 1.5e-09 2.3e-10 1.7e-02 86 TCF4
17 22 40472399 41895409 1 1 1.1e-07 8.1e-08 2.0e-01 94 SLC25A17

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 2.50 2 0 0.0 0.00 1.0e+00 HSD3B7 YPEL3
Major Depression (MDD) 4.72 2 0 0.0 0.00 1.0e+00 TCF4 ZDHHC5
Verbal and Numeric Reasoning (VNR) 4.75 5 2 6.1 0.98 5.6e-04 ITIH4-AS1 MAPT PPIP5K2 SND1 ZDHHC5
Breast Cancer 1.76 1 1 3.0 0.00 1.0e+00 MAPT
Ovarian Cancer 2.45 1 1 3.0 0.00 1.0e+00 MAPT
HDL Cholesterol 1.86 1 1 3.0 0.00 1.0e+00 KCTD10
Neuroticism 7.02 4 1 3.0 -0.99 1.0e-02 AREL1 MAPT SLC25A17 TCF4
Rheumatoid Arthritis 1.86 1 0 0.0 0.00 1.0e+00 PPIP5K2
Schizophrenia 5.29 7 4 12.1 -0.99 4.4e-05 ACTR1A CYP17A1-AS1 IGSF9B ITIH4-AS1 RP11-85F14.5 SLC25A17 ZDHHC5
Triglycerides 1.02 1 0 0.0 0.00 1.0e+00 HSD3B7
Blood Eosinophil Count 2.23 5 5 15.2 -0.22 7.2e-01 ITIH4-AS1 KCTD10 MAPT SLC25A17 YPEL3
Blood Platelet Count 1.47 8 5 15.2 0.47 2.0e-01 AREL1 CYB561D2 CYP17A1-AS1 ITIH4-AS1 RP11-85F14.5 SND1 YPEL3 ZDHHC5
Blood Red Count 3.66 8 5 15.2 -0.67 7.0e-02 AP001877.1 CYB561D2 HSD3B7 ITIH4-AS1 MAPT PPIP5K2 YPEL3 ZDHHC5
Blood White Count 1.18 6 3 9.1 0.50 3.1e-01 ACTR1A KCTD10 MAPT PPIP5K2 PTCH1 RP11-85F14.5
Heel T-Score 1.83 6 1 3.0 -0.28 5.9e-01 AREL1 HSD3B7 MAPT MLH3 SLC25A17 ZDHHC5
BMI 2.58 5 4 12.1 1.00 5.5e-05 ACTR1A CADM2 HSD3B7 ITIH4-AS1 YPEL3
Height 2.45 11 9 27.3 -0.16 6.4e-01 AP001877.1 AREL1 CYB561D2 CYP17A1-AS1 ITIH4-AS1 MAPT PPIP5K2 PTCH1 SEMA3B-AS1 TCF4 YPEL3
Waist Hip Ratio (WHR) 3.13 5 5 15.2 -0.66 2.3e-01 CYB561D2 ITIH4-AS1 MAPT PPIP5K2 RP11-85F14.5
Systolic Blood Pressure 3.54 8 6 18.2 -0.32 4.0e-01 ACTR1A AREL1 CADM2 CYP17A1-AS1 MAPT SND1 YPEL3 ZDHHC5
Smoking Status 5.11 4 3 9.1 0.99 1.1e-02 ACTR1A CADM2 CYP17A1-AS1 ITIH4-AS1
Allergy or Eczema 1.71 2 1 3.0 0.00 1.0e+00 CYP17A1-AS1 SLC25A17
Cardiovascular Disease 1.93 2 1 3.0 0.00 1.0e+00 HSD3B7 RP11-85F14.5
Hypothyroidism (self reported) 1.89 1 1 3.0 0.00 1.0e+00 PPIP5K2
Type 2 Diabetes (T2D) 2.12 1 0 0.0 0.00 1.0e+00 PPIP5K2
Lung FEV1/FVC ratio 2.91 6 3 9.1 0.88 1.9e-02 ACTR1A AREL1 MAPT MLH3 PTCH1 ZDHHC5
Lung FVC 4.74 5 5 15.2 0.15 8.1e-01 HSD3B7 MAPT PTCH1 SEMA3B-AS1 TCF4
Neuroticism 12.77 16 11 33.3 -0.96 3.2e-09 AREL1 CADM2 CYB561D2 CYP17A1-AS1 HSD3B7 IGSF9B KCTD10 MAPT MLH3 PTCH1 RP11-85F14.5 SEMA3B-AS1 SLC25A17 SND1 TCF4 ZDHHC5
Chronotype (morning person) 2.09 1 1 3.0 0.00 1.0e+00 CYB561D2
Hair Pigment 0.14 1 1 3.0 0.00 1.0e+00 SLC25A17
Tanning 0.61 3 2 6.1 0.00 1.0e+00 AREL1 CADM2 ITIH4-AS1
Hand grip strength (left) 5.99 9 5 15.2 -0.33 3.8e-01 ACTR1A AREL1 CADM2 CYP17A1-AS1 IGSF9B ITIH4-AS1 MAPT TCF4 YPEL3
Number of treatments/medications taken 3.29 1 1 3.0 0.00 1.0e+00 AREL1
Sensitivity / hurt feelings 8.37 7 2 6.1 0.93 2.4e-03 IGSF9B KCTD10 MAPT PTCH1 RP11-85F14.5 SND1 ZDHHC5
Frequency of depressed mood in last 2 weeks 5.74 4 0 0.0 1.00 8.9e-04 CYB561D2 MAPT RP11-85F14.5 ZDHHC5
Hearing difficulty/problems: Yes 2.03 1 0 0.0 0.00 1.0e+00 MAPT
Relative age of first facial hair 3.27 1 1 3.0 0.00 1.0e+00 MAPT
Systolic blood pressure, automated reading 3.06 4 2 6.1 0.07 9.3e-01 AREL1 CYP17A1-AS1 MAPT ZDHHC5
Impedance of leg (right) 4.01 12 8 24.2 0.59 4.1e-02 ACTR1A AP001877.1 AREL1 CADM2 CYB561D2 ITIH4-AS1 MAPT MLH3 PTCH1 SEMA3B-AS1 SND1 YPEL3
Leg fat-free mass (left) 2.87 6 5 15.2 -0.68 1.3e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Trunk fat percentage 2.39 5 3 9.1 -0.78 1.2e-01 AREL1 HSD3B7 MAPT SLC25A17 ZDHHC5
Hand grip strength (right) 4.60 5 2 6.1 -0.98 2.6e-03 ACTR1A CYP17A1-AS1 MAPT TCF4 YPEL3
Current tobacco smoking 2.78 2 1 3.0 0.00 1.0e+00 ACTR1A SLC25A17
Maternal smoking around birth 3.22 1 1 3.0 0.00 1.0e+00 ACTR1A
Fed-up feelings 5.24 4 3 9.1 1.00 2.6e-03 AREL1 MAPT RP11-85F14.5 ZDHHC5
Frequency of unenthusiasm / disinterest in last 2 weeks 4.78 2 0 0.0 0.00 1.0e+00 RP11-85F14.5 ZDHHC5
Relative age voice broke 2.75 1 1 3.0 0.00 1.0e+00 MAPT
Taking other prescription medications 3.41 1 1 3.0 0.00 1.0e+00 AREL1
Age when periods started (menarche) 1.24 1 0 0.0 0.00 1.0e+00 MAPT
Heel bone mineral density (BMD) T-score, automated (left) 1.77 1 0 0.0 0.00 1.0e+00 MAPT
High blood pressure 1.62 2 0 0.0 0.00 1.0e+00 HSD3B7 MAPT
Sitting height 2.73 6 5 15.2 0.00 1.0e+00 CYP17A1-AS1 ITIH4-AS1 MAPT PTCH1 YPEL3 ZDHHC5
Body mass index (BMI) 2.38 5 4 12.1 -0.99 4.4e-04 ACTR1A CADM2 HSD3B7 ITIH4-AS1 YPEL3
Impedance of leg (left) 3.83 11 7 21.2 0.68 2.2e-02 ACTR1A AP001877.1 AREL1 CADM2 CYB561D2 ITIH4-AS1 MAPT MLH3 SEMA3B-AS1 SND1 YPEL3
Leg predicted mass (left) 2.86 6 5 15.2 -0.68 1.4e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Trunk fat mass 2.33 5 2 6.1 0.75 1.4e-01 CADM2 CYP17A1-AS1 HSD3B7 MAPT YPEL3
Waist circumference 2.38 4 3 9.1 0.98 1.7e-02 CADM2 CYP17A1-AS1 HSD3B7 YPEL3
Number of incorrect matches in round 3.48 1 0 0.0 0.00 1.0e+00 CYP17A1-AS1
Past tobacco smoking 4.75 4 2 6.1 0.97 3.2e-02 ACTR1A CADM2 CYP17A1-AS1 ITIH4-AS1
Alcohol usually taken with meals 2.33 2 0 0.0 0.00 1.0e+00 ACTR1A ZDHHC5
Nervous feelings 11.19 12 7 21.2 0.97 1.1e-07 ACTR1A AREL1 CADM2 CYB561D2 CYP17A1-AS1 HSD3B7 ITIH4-AS1 MAPT RP11-85F14.5 SEMA3B-AS1 SLC25A17 YPEL3
Frequency of tenseness / restlessness in last 2 weeks 5.95 3 1 3.0 0.00 1.0e+00 KCTD10 MAPT RP11-85F14.5
Hearing difficulty/problems with background noise 2.23 1 1 3.0 0.00 1.0e+00 MAPT
Hair/balding pattern: Pattern 2 1.86 1 0 0.0 0.00 1.0e+00 MAPT
Had menopause 1.89 1 0 0.0 0.00 1.0e+00 SEMA3B-AS1
Forced vital capacity (FVC) 3.89 4 3 9.1 0.50 5.0e-01 HSD3B7 ITIH4-AS1 MAPT PTCH1
Heel bone mineral density (BMD) T-score, automated (right) 1.84 1 0 0.0 0.00 1.0e+00 MAPT
Ever unenthusiastic/disinterested for a whole week 3.30 2 0 0.0 0.00 1.0e+00 CYB561D2 MAPT
Qualifications: None of the above 2.87 2 1 3.0 0.00 1.0e+00 ACTR1A AP001877.1
Mouth/teeth dental problems 2.19 2 0 0.0 0.00 1.0e+00 KCTD10 MAPT
Fluid intelligence score 3.36 2 0 0.0 0.00 1.0e+00 MAPT PPIP5K2
Neuroticism score 12.12 14 11 33.3 0.98 2.9e-09 AREL1 CADM2 CYB561D2 HSD3B7 IGSF9B KCTD10 MAPT MLH3 PTCH1 RP11-85F14.5 SEMA3B-AS1 SLC25A17 TCF4 ZDHHC5
Weight 2.70 5 5 15.2 -0.94 1.6e-02 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 YPEL3
Impedance of arm (right) 3.65 9 5 15.2 0.72 3.0e-02 ACTR1A CADM2 CYB561D2 ITIH4-AS1 MAPT MLH3 SEMA3B-AS1 YPEL3 ZDHHC5
Arm fat percentage (right) 2.12 4 2 6.1 0.20 8.0e-01 HSD3B7 ITIH4-AS1 YPEL3 ZDHHC5
Trunk fat-free mass 3.02 6 5 15.2 -0.66 1.5e-01 ACTR1A CADM2 CYP17A1-AS1 MLH3 PTCH1 YPEL3
Hip circumference 2.78 6 2 6.1 -0.71 1.1e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Frequency of tiredness / lethargy in last 2 weeks 4.50 2 1 3.0 0.00 1.0e+00 KCTD10 ZDHHC5
Falls in the last year 3.04 1 1 3.0 0.00 1.0e+00 SEMA3B-AS1
Hair/balding pattern: Pattern 3 3.23 1 1 3.0 0.00 1.0e+00 MAPT
Number of live births 1.55 1 0 0.0 0.00 1.0e+00 MAPT
Forced expiratory volume in 1-second (FEV1) 3.67 3 3 9.1 0.00 1.0e+00 HSD3B7 MAPT PTCH1
Noisy workplace 1.96 1 0 0.0 0.00 1.0e+00 MAPT
Qualifications: A levels/AS levels or equivalent 2.95 3 1 3.0 0.00 1.0e+00 ACTR1A AP001877.1 MAPT
Serious illness, injury or assault of a close relative in last 2 years 2.21 1 0 0.0 0.00 1.0e+00 SND1
Medication: Ibuprofen (e.g. Nurofen) 1.56 1 0 0.0 0.00 1.0e+00 MAPT
Forced expiratory volume in 1-second (FEV1), Best measure 3.32 3 2 6.1 0.00 1.0e+00 HSD3B7 MAPT PTCH1
Impedance of arm (left) 3.68 8 6 18.2 0.67 6.7e-02 ACTR1A CADM2 CYB561D2 ITIH4-AS1 MAPT SEMA3B-AS1 YPEL3 ZDHHC5
Arm fat mass (right) 2.19 3 3 9.1 0.00 1.0e+00 CADM2 HSD3B7 YPEL3
Trunk predicted mass 3.02 6 5 15.2 -0.66 1.5e-01 ACTR1A CADM2 CYP17A1-AS1 MLH3 PTCH1 YPEL3
Standing height 2.20 7 6 18.2 0.21 6.5e-01 CYP17A1-AS1 ITIH4-AS1 MAPT PPIP5K2 PTCH1 SEMA3B-AS1 YPEL3
Tense / 'highly strung' 7.86 8 2 6.1 0.99 7.1e-07 AREL1 CADM2 CYB561D2 HSD3B7 MAPT RP11-85F14.5 SEMA3B-AS1 SLC25A17
Seen doctor (GP) for nerves, anxiety, tension or depression 4.72 3 1 3.0 0.00 1.0e+00 AREL1 IGSF9B TCF4
Hair/balding pattern: Pattern 4 5.02 1 1 3.0 0.00 1.0e+00 MAPT
Birth weight of first child 2.64 1 0 0.0 0.00 1.0e+00 SND1
Peak expiratory flow (PEF) 3.02 1 1 3.0 0.00 1.0e+00 MAPT
Qualifications: O levels/GCSEs or equivalent 1.51 1 0 0.0 0.00 1.0e+00 AP001877.1
Medication: Paracetamol 3.98 1 1 3.0 0.00 1.0e+00 MAPT
Headache pain in last month 4.11 3 1 3.0 0.00 1.0e+00 ITIH4-AS1 MAPT ZDHHC5
Hypothyroidism/myxoedema (self-reported) 1.78 1 0 0.0 0.00 1.0e+00 PPIP5K2
Birth weight 3.13 3 2 6.1 0.59 4.1e-01 CYP17A1-AS1 PTCH1 SND1
Chronic bronchitis/emphysema (mother) 2.83 1 0 0.0 0.00 1.0e+00 MLH3
High blood pressure (siblings) 2.02 1 0 0.0 0.00 1.0e+00 HSD3B7
Forced vital capacity (FVC), Best measure 3.64 4 3 9.1 0.48 5.2e-01 HSD3B7 ITIH4-AS1 MAPT PTCH1
Body fat percentage 2.34 3 2 6.1 0.00 1.0e+00 AREL1 HSD3B7 ZDHHC5
Leg fat percentage (right) 2.34 3 2 6.1 0.00 1.0e+00 AP001877.1 AREL1 HSD3B7
Arm fat-free mass (right) 2.91 5 4 12.1 -0.76 1.4e-01 ACTR1A CADM2 CYP17A1-AS1 PTCH1 YPEL3
Exposure to tobacco smoke outside home 2.61 1 0 0.0 0.00 1.0e+00 ACTR1A
Comparative body size at age 10 2.77 3 2 6.1 0.00 1.0e+00 CADM2 CYB561D2 HSD3B7
Worry too long after embarrassment 5.63 4 2 6.1 1.00 3.8e-04 KCTD10 MAPT RP11-85F14.5 ZDHHC5
Number of children fathered 1.68 1 0 0.0 0.00 1.0e+00 CADM2
Age at first live birth 2.06 1 0 0.0 0.00 1.0e+00 AP001877.1
Pulse wave peak to peak time 2.30 1 0 0.0 0.00 1.0e+00 CYP17A1-AS1
Qualifications: College or University degree 3.24 6 3 9.1 -0.71 1.1e-01 ACTR1A AP001877.1 MAPT PPIP5K2 SND1 ZDHHC5
Medication for pain relief, constipation, heartburn 3.37 2 1 3.0 0.00 1.0e+00 AREL1 MAPT
Whole body fat mass 2.29 4 2 6.1 0.94 5.9e-02 CADM2 CYP17A1-AS1 HSD3B7 YPEL3
Leg fat mass (right) 2.47 5 3 9.1 -0.95 1.2e-02 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 YPEL3
Arm predicted mass (right) 2.88 6 4 12.1 -0.72 1.0e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Pulse rate, automated reading 1.98 2 0 0.0 0.00 1.0e+00 CYB561D2 ZDHHC5
Alcohol intake frequency. 4.25 5 4 12.1 0.55 3.4e-01 CADM2 MAPT TCF4 YPEL3 ZDHHC5
Comparative height size at age 10 2.28 6 6 18.2 0.31 5.4e-01 CYP17A1-AS1 ITIH4-AS1 MAPT PTCH1 TCF4 YPEL3
Suffer from 'nerves' 6.60 3 1 3.0 0.00 1.0e+00 AREL1 CADM2 MAPT
Age at last live birth 2.24 1 0 0.0 0.00 1.0e+00 AP001877.1
Hypertension (Self-reported) 1.77 2 0 0.0 0.00 1.0e+00 HSD3B7 MAPT
Smoking status: Previous 3.90 2 1 3.0 0.00 1.0e+00 ACTR1A CADM2
Forced expiratory volume in 1-second (FEV1), predicted 2.04 2 0 0.0 0.00 1.0e+00 CYP17A1-AS1 PTCH1
Whole body fat-free mass 3.00 5 5 15.2 -0.71 1.8e-01 ACTR1A CADM2 CYP17A1-AS1 PTCH1 YPEL3
Leg fat-free mass (right) 2.94 5 5 15.2 -0.69 1.9e-01 ACTR1A CADM2 CYP17A1-AS1 PTCH1 YPEL3
Arm fat percentage (left) 2.03 4 1 3.0 0.09 9.1e-01 HSD3B7 ITIH4-AS1 YPEL3 ZDHHC5
Average weekly red wine intake 3.63 3 1 3.0 0.00 1.0e+00 AP001877.1 CADM2 ZDHHC5
Handedness (chirality/laterality): Left-handed 2.42 1 1 3.0 0.00 1.0e+00 MAPT
Mood swings 7.89 4 3 9.1 0.99 1.4e-02 AREL1 MAPT SLC25A17 TCF4
Loneliness, isolation 3.10 2 0 0.0 0.00 1.0e+00 MAPT RP11-85F14.5
Friendships satisfaction 2.93 1 0 0.0 0.00 1.0e+00 AP001877.1
Qualifications: nursing, teaching 1.72 1 0 0.0 0.00 1.0e+00 AP001877.1
Mouth/teeth dental problems: Mouth ulcers 3.74 3 1 3.0 0.00 1.0e+00 AP001877.1 MAPT PPIP5K2
Medication for cholesterol 2.47 2 0 0.0 0.00 1.0e+00 HSD3B7 MAPT
Smoking status: Current 2.78 1 1 3.0 0.00 1.0e+00 ACTR1A
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.18 2 2 6.1 0.00 1.0e+00 HSD3B7 MAPT
Whole body water mass 3.00 5 5 15.2 -0.71 1.8e-01 ACTR1A CADM2 CYP17A1-AS1 PTCH1 YPEL3
Leg predicted mass (right) 2.95 6 5 15.2 -0.64 1.7e-01 ACTR1A CADM2 CYP17A1-AS1 PTCH1 SND1 YPEL3
Arm fat mass (left) 2.22 4 3 9.1 -0.98 1.5e-02 ACTR1A CADM2 HSD3B7 YPEL3
Number of self-reported non-cancer illnesses 2.20 1 0 0.0 0.00 1.0e+00 AREL1
Average weekly champagne plus white wine intake 1.72 1 0 0.0 0.00 1.0e+00 MAPT
Miserableness 4.34 3 2 6.1 0.00 1.0e+00 MAPT RP11-85F14.5 TCF4
Guilty feelings 5.83 4 2 6.1 1.00 2.7e-03 AREL1 MAPT PTCH1 ZDHHC5
Medication: Blood pressure 2.12 1 1 3.0 0.00 1.0e+00 MAPT
Medication: Paracetamol 3.73 1 1 3.0 0.00 1.0e+00 MAPT
Ever smoked 3.75 3 2 6.1 0.00 1.0e+00 ACTR1A CADM2 CYP17A1-AS1
Basal metabolic rate 2.94 6 5 15.2 -0.69 1.3e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Leg fat percentage (left) 2.28 3 2 6.1 0.00 1.0e+00 AREL1 HSD3B7 ITIH4-AS1
Arm fat-free mass (left) 2.92 6 4 12.1 -0.72 1.1e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3
Irritability 5.62 5 2 6.1 0.98 2.2e-03 AREL1 HSD3B7 MAPT SLC25A17 TCF4
Risk taking 4.65 3 1 3.0 -0.99 1.5e-02 CADM2 RP11-85F14.5 SND1
Fractured/broken bones in last 5 years 2.74 2 0 0.0 0.00 1.0e+00 MAPT SEMA3B-AS1
Diastolic blood pressure, automated reading 1.14 1 0 0.0 0.00 1.0e+00 HSD3B7
Ever depressed for a whole week 2.14 1 0 0.0 0.00 1.0e+00 MAPT
Vascular/heart problems diagnosed by doctor 1.54 1 0 0.0 0.00 1.0e+00 HSD3B7
Cholesterol lowering medication 1.81 1 0 0.0 0.00 1.0e+00 HSD3B7
Pain experienced in last month 2.79 3 0 0.0 0.00 1.0e+00 HSD3B7 KCTD10 MAPT
Impedance of whole body 4.19 10 7 21.2 0.61 6.4e-02 ACTR1A AREL1 CADM2 CYB561D2 ITIH4-AS1 MAPT MLH3 SEMA3B-AS1 SND1 YPEL3
Leg fat mass (left) 2.43 5 3 9.1 -0.94 1.6e-02 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 YPEL3
Arm predicted mass (left) 2.96 6 5 15.2 -0.71 1.1e-01 ACTR1A CADM2 CYP17A1-AS1 HSD3B7 PTCH1 YPEL3

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 21 0.602 1.85
GTEx Adipose Visceral Omentum 11 0.540 2.01
GTEx Adrenal Gland 10 0.686 2.07
GTEx Artery Aorta 20 0.672 1.98
GTEx Artery Coronary 11 0.930 2.08
GTEx Artery Tibial 15 0.399 1.90
GTEx Brain Caudate basal ganglia 7 0.761 2.04
GTEx Brain Cerebellar Hemisphere 10 0.672 1.98
GTEx Brain Cerebellum 11 0.555 1.91
GTEx Brain Cortex 8 0.773 2.15
GTEx Brain Frontal Cortex BA9 7 0.758 2.15
GTEx Brain Hippocampus 5 0.954 2.15
GTEx Brain Hypothalamus 5 0.847 2.09
GTEx Brain Nucleus accumbens basal ganglia 7 0.809 2.04
GTEx Brain Putamen basal ganglia 6 0.962 2.12
GTEx Breast Mammary Tissue 14 0.709 2.00
GTEx Breast Mammary Tissue (Male) 10 0.838 2.00
GTEx Breast Mammary Tissue (Female) 10 0.608 1.94
GTEx Cells EBV-transformed lymphocytes 16 1.124 2.14
GTEx Cells Transformed fibroblasts 15 0.357 1.81
GTEx Colon Sigmoid 13 0.889 2.06
GTEx Colon Transverse 15 0.727 2.07
GTEx Esophagus Gastroesophageal Junction 10 0.692 2.09
GTEx Esophagus Mucosa 17 0.512 1.90
GTEx Esophagus Muscularis 16 0.495 2.01
GTEx Heart Atrial Appendage 12 0.760 2.03
GTEx Heart Left Ventricle 11 0.719 2.14
GTEx Liver 8 1.116 2.08
GTEx Lung 21 0.731 1.95
GTEx Muscle Skeletal 16 0.554 1.92
GTEx Nerve Tibial 18 0.417 1.87
GTEx Ovary 8 0.881 2.09
GTEx Pancreas 12 0.735 2.08
GTEx Pituitary 7 0.628 2.06
GTEx Prostate 8 0.958 2.06
GTEx Skin Not Sun Exposed Suprapubic 14 0.569 1.97
GTEx Skin Sun Exposed Lower leg 20 0.549 1.93
GTEx Small Intestine Terminal Ileum 7 1.518 2.32
GTEx Spleen 9 0.638 2.04
GTEx Stomach 9 0.619 2.07
GTEx Testis 22 0.697 1.93
GTEx Thyroid 22 0.550 1.94
GTEx Uterus 8 1.411 2.20
GTEx Vagina 6 0.945 2.15
GTEx Whole Blood 11 0.552 1.84
METSIM Adipose 7 0.152 1.67
NTR Blood 6 0.250 1.81
ROSMAP Brain Pre-frontal Cortex 27 0.615 2.12
YFS Blood 7 0.152 1.62
CommonMind Brain Pre-frontal Cortex 18 0.335 1.86
TCGA Breast Tumor 2 0.261 1.99
TCGA Breast Normal 5 0.119 1.69
TCGA Ovarian Tumor 19 0.650 1.77
TCGA Prostate Tumor 8 0.231 1.76