TWAS hub - MLH3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0870	0.0230	2.5e-14	0.136	0.095	0.151	0.133	0.153	3.4e-16	1.2e-11	5.8e-18	7.8e-16	3.6e-18
2	GTEx	Artery Aorta	0.1900	0.0660	4.2e-04	0.067	NA	0.017	NA	0.001	1.5e-04	NA	3.9e-02	NA	2.7e-01
3	GTEx	Cells Transformed fibroblasts	0.0680	0.0290	2.2e-03	0.029	NA	0.013	NA	0.017	2.9e-03	NA	3.5e-02	NA	1.8e-02
4	GTEx	Colon Sigmoid	0.1690	0.0690	4.1e-03	0.018	NA	0.003	NA	-0.002	7.3e-02	NA	2.4e-01	NA	3.9e-01
5	GTEx	Testis	0.0970	0.0460	4.4e-03	0.014	NA	0.002	NA	0.005	7.4e-02	NA	2.6e-01	NA	1.8e-01
6	NTR	Blood	0.0152	0.0069	8.6e-04	0.011	0.009	0.010	0.009	0.010	1.5e-04	6.2e-04	3.0e-04	3.4e-04	3.3e-04
7	TCGA	Breast Invasive Carcinoma	0.0792	0.0358	0.0e+00	0.081	0.086	0.092	NA	0.095	3.2e-16	3.3e-17	2.5e-18	NA	7.2e-19
8	TCGA	Cervical Squamous Cell Carcinoma	0.0530	0.0400	1.7e-03	0.072	0.015	0.057	NA	0.012	1.9e-04	6.1e-02	8.9e-04	NA	8.1e-02
9	TCGA	Colon Adenocarcinoma	0.0710	0.0460	4.8e-05	0.081	0.061	0.064	NA	0.058	2.0e-05	2.0e-04	1.5e-04	NA	2.8e-04
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0630	0.0276	6.3e-14	0.131	0.125	0.130	NA	0.129	1.8e-14	6.8e-14	2.1e-14	NA	2.4e-14
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0698	0.0432	7.1e-09	0.090	0.078	0.069	NA	0.076	2.7e-10	3.9e-09	2.9e-08	NA	5.8e-09
12	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0670	0.0480	3.4e-04	0.071	0.065	0.028	NA	0.051	7.0e-05	1.4e-04	9.7e-03	NA	6.7e-04
13	TCGA	Brain Lower Grade Glioma	0.1463	0.0768	8.4e-07	0.052	0.044	0.036	NA	0.041	1.3e-06	9.0e-06	6.0e-05	NA	1.7e-05
14	TCGA	Liver Hepatocellular Carcinoma	0.1290	0.0810	1.5e-03	0.011	0.010	0.024	NA	0.000	8.9e-02	1.1e-01	2.5e-02	NA	3.2e-01
15	TCGA	Lung Adenocarcinoma	0.0629	0.0386	4.6e-09	0.070	0.063	0.052	NA	0.063	1.4e-08	6.5e-08	1.0e-06	NA	6.5e-08
16	TCGA	Lung Squamous Cell Carcinoma	0.0949	0.0492	1.2e-11	0.115	0.116	0.120	NA	0.124	5.6e-13	3.9e-13	1.6e-13	NA	6.0e-14
17	TCGA	Ovarian Serous Cystadenocarcinoma	0.1370	0.0760	3.4e-05	0.067	0.082	0.083	NA	0.074	2.5e-05	3.6e-06	2.9e-06	NA	9.6e-06
18	TCGA	Pancreatic Adenocarcinoma	0.0940	0.0610	1.7e-04	0.090	0.054	0.082	NA	0.069	1.3e-04	2.6e-03	2.7e-04	NA	7.7e-04
19	TCGA	Prostate Adenocarcinoma	0.0938	0.0464	3.3e-11	0.126	0.108	0.111	NA	0.123	4.3e-13	2.2e-11	1.3e-11	NA	7.5e-13
20	TCGA	Rectum Adenocarcinoma	0.2160	0.1510	8.1e-03	0.014	0.012	-0.005	NA	-0.007	1.5e-01	1.6e-01	4.4e-01	NA	4.9e-01
21	TCGA	Stomach Adenocarcinoma	0.0660	0.0470	3.3e-05	0.064	0.064	0.044	NA	0.059	2.2e-05	2.1e-05	3.7e-04	NA	4.4e-05
22	TCGA	Testicular Germ Cell Tumors	0.1280	0.0670	1.9e-05	0.160	0.087	0.126	NA	0.120	2.6e-06	5.3e-04	3.4e-05	NA	5.2e-05
23	TCGA	Thyroid Carcinoma	0.1420	0.0620	0.0e+00	0.197	0.195	0.195	NA	0.197	7.6e-19	1.0e-18	1.1e-18	NA	6.6e-19

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Heel T-Score	8.3	66.0	78.9	8.6	7.2	8.9	-4.3	8.1	7.4	8.4	7.8	7.4	8.7	8.3	8.4	8.5	8.2	8.2	8.6	7.5	8.2	8.6	8.5	8.5	8.7	8.7
Heart disease (mother)	8.3	10.1	13.2	3.2	2.9	3.6	-1.0	3.1	2.8	2.9	3.0	2.5	3.4	3.3	3.2	3.5	3.4	3.1	3.2	3.3	3.6	3.5	3.4	3.5	3.5	3.5
Mouth/teeth dental problems: Mouth ulcers	8.3	13.1	21.5	-3.5	-3.5	-3.6	1.9	-2.8	-4.1	-3.1	-3.4	-3.0	-3.4	-3.6	-3.4	-3.0	-4.3	-3.9	-3.8	-4.6	-3.6	-4.3	-3.7	-4.0	-3.9	-4.0
Coronary Artery Disease (CAD)	7.0	8.4	11.8	3.3	2.9	3.3	-2.3	3.1	2.9	3.4	3.0	2.7	3.0	2.9	3.0	2.7	2.8	3.0	3.4	2.3	0.0	2.9	2.9	3.0	3.1	3.1
Hearing aid user	6.8	7.7	10.4	-2.8	-2.2	-3.0	1.3	-3.1	-3.0	-2.8	-3.2	-2.7	-2.7	-2.9	-2.9	-2.2	-2.9	-3.1	-2.9	-2.1	-2.3	-3.1	-2.7	-3.1	-3.1	-2.9
Average weekly spirits intake	6.2	7.7	10.0	-2.9	-2.5	-2.7	1.4	-2.8	-2.9	-3.0	-3.0	-2.5	-2.6	-2.9	-2.7	-2.2	-2.7	-3.2	-3.2	-2.6	-2.7	-3.1	-2.7	-3.1	-2.9	-2.9
Hearing difficulty/problems: Yes	6.0	9.1	14.6	-3.1	-2.7	-3.1	0.7	-3.1	-2.6	-3.8	-3.2	-2.6	-3.0	-2.9	-2.9	-3.1	-3.1	-3.3	-3.7	-2.6	-2.6	-3.3	-2.8	-3.3	-3.2	-3.2
Illness, injury, bereavement, stress in last 2 years	6.0	7.3	11.2	3.0	1.9	2.8	0.1	3.1	2.7	2.3	3.3	2.3	2.6	2.9	2.9	1.2	2.5	3.3	2.7	2.3	3.1	3.0	2.7	3.3	3.0	2.9
Heel bone mineral density (BMD) T-score, automated (left)	5.8	13.1	16.5	3.7	3.2	4.1	-2.3	3.8	3.1	3.5	3.4	3.1	4.0	3.6	3.7	3.9	3.7	3.5	3.6	3.5	4.0	3.8	3.9	3.7	3.9	3.9
Rheumatoid Arthritis	5.6	7.7	12.9	-3.0	-3.0	-2.8	-0.8	-2.7	-3.1	-3.6	-2.9	-3.1	-3.0	-2.8	-2.9	-2.6	-2.4	-2.9	-3.2	-2.0	-1.9	-2.8	-2.8	-2.7	-2.9	-2.9
Systolic Blood Pressure	5.6	27.9	38.0	5.4	6.2	5.5	0.5	5.3	5.9	5.9	5.6	6.0	5.7	5.6	5.7	5.3	4.4	5.6	5.6	3.7	2.9	5.5	5.6	5.2	5.6	5.4
Medication: Amlodipine	5.6	7.8	10.6	3.0	2.9	2.9	0.7	3.1	2.9	2.6	3.3	3.0	3.0	3.2	3.2	2.0	2.3	3.2	2.7	1.9	2.3	2.9	3.0	3.1	3.0	2.9
Age at First Birth	5.5	8.1	12.3	3.1	2.5	3.2	-1.1	2.5	2.9	2.4	2.2	2.5	3.1	2.9	2.9	2.9	3.2	2.5	2.8	3.2	3.5	3.0	3.1	2.9	2.9	3.0
Hypothyroidism (self reported)	5.0	11.5	16.5	4.1	2.8	3.8	-1.9	3.7	3.1	3.3	3.5	2.8	3.3	3.6	3.5	3.2	3.3	3.6	3.5	2.8	3.6	3.7	3.5	3.7	3.8	3.6
Heel bone mineral density (BMD) T-score, automated (right)	5.0	11.5	14.4	3.4	3.0	3.8	-2.5	3.4	3.0	3.2	3.1	2.9	3.7	3.3	3.4	3.6	3.5	3.3	3.3	3.5	3.8	3.6	3.6	3.5	3.6	3.6
Fractured/broken bones in last 5 years	5.0	6.4	9.4	-2.4	-2.4	-2.7	0.7	-2.2	-2.6	-2.3	-2.1	-2.0	-2.4	-2.6	-2.5	-2.6	-3.1	-2.5	-2.7	-2.9	-2.5	-3.0	-2.6	-2.8	-2.7	-2.8
Worry (Nagel 2018)	4.9	10.3	33.3	2.9	3.7	2.8	-5.8	3.4	3.0	3.0	3.2	4.1	3.4	3.5	3.3	2.3	2.5	3.1	2.8	2.2	2.0	2.9	3.4	2.9	3.0	3.0
Fed-up feelings	4.8	8.8	14.4	2.8	3.2	2.9	-3.8	3.7	3.0	2.8	3.3	3.0	3.1	3.2	3.0	2.1	2.2	3.3	2.9	1.9	2.4	2.8	3.0	3.1	3.0	2.9
Angina	4.6	6.1	10.9	2.5	2.9	2.8	1.5	2.2	2.2	2.4	1.8	2.6	2.9	2.6	2.4	3.3	2.4	2.1	2.4	2.3	2.3	2.3	2.8	2.2	2.5	2.6
Angina (self-reported)	4.3	5.6	10.9	2.4	2.9	2.7	1.5	2.0	2.0	2.4	1.7	2.5	2.8	2.4	2.3	3.3	2.4	2.0	2.3	2.3	2.2	2.3	2.7	2.1	2.4	2.5
Neuroticism (Nagel 2018)	4.0	9.4	34.8	3.0	2.9	2.8	-5.9	3.8	2.7	2.4	3.4	2.9	2.9	3.4	3.1	1.7	2.4	3.2	2.5	2.0	2.4	2.8	3.1	3.2	3.0	3.0
Medication: Levothyroxine sodium	3.9	6.6	9.0	2.9	2.4	3.0	-1.7	2.7	2.5	1.9	2.5	2.2	2.7	2.8	2.7	2.2	2.6	2.5	2.2	2.2	2.8	2.7	2.8	2.8	2.9	2.8
Impedance of leg (left)	3.9	18.9	21.7	4.6	4.3	4.4	-4.5	3.6	4.3	4.0	3.8	4.4	4.5	4.7	4.2	4.1	4.6	4.1	4.2	4.6	4.3	4.6	4.6	4.3	4.4	4.5
Hypothyroidism/myxoedema (self-reported)	3.8	7.5	9.7	3.1	2.4	3.0	-2.6	2.9	2.6	2.3	2.7	2.2	2.7	2.8	2.7	2.4	2.8	2.7	2.5	2.5	3.0	2.9	2.9	2.9	3.0	2.9
Impedance of leg (right)	3.7	17.7	20.4	4.5	4.4	4.2	-4.3	3.4	4.2	3.9	3.6	4.3	4.3	4.5	4.0	4.1	4.4	3.9	4.1	4.4	4.3	4.4	4.5	4.1	4.2	4.3
Medication: Allopurinol	3.7	4.9	7.4	2.6	2.2	2.4	0.2	2.3	2.7	2.4	2.0	1.9	2.3	2.3	2.2	2.4	2.1	2.2	2.4	1.9	1.9	2.3	2.2	2.3	2.3	2.3
Commuting to job workplace: Cycle	3.7	4.4	6.1	2.0	1.6	2.1	2.5	1.6	2.3	1.6	2.0	1.9	2.1	2.1	2.2	1.9	2.2	2.2	1.9	2.4	2.4	2.3	2.2	2.2	2.2	2.2
Systolic blood pressure, automated reading	3.6	10.5	15.4	3.2	3.9	3.3	0.1	2.8	3.7	3.7	3.1	3.8	3.5	3.4	3.4	3.6	3.0	3.3	3.5	2.7	1.4	3.4	3.5	3.0	3.3	3.4
Osteoporosis (self-reported)	3.6	4.5	6.9	-2.1	-2.3	-2.3	-1.9	-1.3	-1.9	-1.9	-1.3	-1.9	-2.4	-2.1	-2.0	-2.6	-2.5	-1.7	-2.1	-2.6	-2.2	-2.2	-2.3	-2.0	-2.1	-2.3
Nervous feelings	3.4	6.4	12.0	2.2	3.4	2.3	-2.7	3.0	2.3	2.8	2.8	3.5	2.7	2.8	2.7	2.2	1.7	2.7	2.5	1.4	0.9	2.3	2.6	2.3	2.5	2.4
Medication for cholesterol	3.4	5.2	8.9	-2.1	-3.0	-2.2	2.2	-1.8	-2.1	-2.3	-1.6	-2.9	-2.5	-2.5	-2.2	-2.9	-2.2	-1.9	-2.1	-2.1	-2.1	-2.2	-2.5	-1.9	-2.1	-2.2
Falls in the last year	3.2	4.4	5.7	-2.1	-2.0	-2.2	0.4	-1.8	-2.1	-2.2	-1.9	-1.9	-2.1	-2.1	-2.0	-2.0	-2.4	-2.1	-2.3	-2.3	-2.1	-2.4	-2.1	-2.2	-2.2	-2.2
Suffer from ‘nerves’	3.2	5.0	10.7	1.8	2.8	2.0	-3.3	2.7	2.0	2.0	2.4	2.9	2.5	2.4	2.4	1.5	1.5	2.3	1.9	1.6	1.6	1.9	2.4	2.0	2.1	2.1
Neuroticism	2.9	7.1	37.4	2.3	2.8	2.1	-6.1	3.0	2.2	2.4	2.7	3.0	2.5	2.9	2.5	1.6	1.8	2.7	2.3	1.5	1.4	2.3	2.6	2.4	2.3	2.3
Ulcerative Colitis (UC)	2.7	5.0	7.0	-2.2	-1.5	-2.5	0.0	-2.2	-2.3	-1.9	-2.4	-1.8	-2.1	-2.5	-2.4	-1.7	-2.5	-2.5	-2.2	-2.4	-2.1	-2.6	-2.5	-2.7	-2.5	-2.6
Alcohol usually taken with meals	2.7	4.3	6.1	-2.2	-1.4	-2.2	0.9	-2.3	-2.2	-2.1	-2.4	-1.6	-1.9	-2.2	-2.1	-1.6	-2.0	-2.4	-2.3	-1.7	-1.9	-2.4	-2.0	-2.5	-2.4	-2.3
Average weekly champagne plus white wine intake	2.7	3.7	5.3	2.3	2.3	2.0	0.3	1.8	1.7	1.7	1.6	1.9	2.1	1.9	1.9	2.0	2.0	1.8	1.9	2.2	2.0	1.9	2.1	1.9	1.9	2.0
Depressed Affect (Nagel 2018)	2.6	5.5	23.1	2.1	2.0	2.2	-4.8	3.2	1.9	1.7	2.8	2.0	2.2	2.5	2.5	0.9	1.5	2.6	1.9	1.1	1.9	2.1	2.2	2.5	2.3	2.2
Illnesses of father: None of the above (group 1)	2.6	3.2	4.8	-2.0	-1.9	-1.8	-0.2	-1.8	-1.7	-2.2	-1.9	-1.8	-1.8	-1.8	-1.8	-1.9	-1.7	-1.9	-2.0	-1.2	-1.1	-1.9	-1.7	-1.9	-1.9	-1.9
Leg predicted mass (right)	2.6	13.9	16.8	-3.9	-3.3	-3.6	3.3	-3.7	-3.6	-3.9	-4.1	-4.1	-3.8	-4.0	-3.9	-2.9	-3.4	-4.0	-3.9	-3.2	-3.8	-4.0	-3.8	-3.9	-3.9	-3.8
Number of treatments/medications taken	2.5	4.5	12.2	2.2	2.4	2.1	-3.5	2.7	1.7	2.1	2.3	2.5	2.2	2.4	2.1	1.8	1.4	2.1	1.9	0.9	1.3	1.8	2.2	2.0	2.0	1.9
Medication: Atenolol	2.5	3.1	5.8	1.7	2.0	1.8	0.8	2.2	1.7	1.5	1.9	2.4	2.1	2.1	2.2	1.3	1.1	1.9	1.5	1.1	1.6	1.6	2.1	1.7	1.8	1.7
Ever unenthusiastic/disinterested for a whole week	2.5	3.1	4.5	2.0	2.0	1.6	-2.1	2.1	1.4	2.1	1.9	1.9	1.8	1.9	1.7	1.5	1.3	1.8	1.9	0.9	1.3	1.7	1.7	1.7	1.7	1.7
Leg fat-free mass (right)	2.5	13.5	16.4	-3.8	-3.3	-3.6	3.4	-3.7	-3.6	-3.8	-4.0	-4.0	-3.7	-4.0	-3.8	-2.9	-3.3	-4.0	-3.8	-3.1	-3.7	-3.9	-3.7	-3.8	-3.8	-3.7
Taking other prescription medications	2.4	3.7	10.0	2.3	2.4	1.8	-3.2	2.2	1.8	1.8	1.9	2.3	1.8	2.2	1.8	1.8	1.5	1.8	1.7	1.0	1.0	1.8	2.0	1.8	1.9	1.8
Hearing difficulty/problems with background noise	2.4	3.9	6.6	-2.2	-1.2	-2.1	-0.8	-1.7	-1.8	-1.5	-2.2	-1.0	-1.7	-1.8	-1.9	-1.2	-2.4	-2.2	-2.1	-2.4	-2.3	-2.6	-1.8	-2.5	-2.3	-2.2
Had other major operations	2.4	3.0	5.1	-2.0	-1.6	-1.7	-1.4	-0.9	-1.8	-1.5	-1.4	-1.2	-1.5	-1.6	-1.6	-1.8	-2.1	-1.7	-1.8	-2.3	-1.6	-2.1	-1.7	-1.9	-1.8	-1.9
Neuroticism score	2.4	5.0	18.9	2.0	2.8	1.9	-4.3	2.6	1.9	2.0	2.1	2.6	2.4	2.3	2.1	1.7	1.6	2.2	1.9	1.5	1.4	1.9	2.2	2.0	2.0	2.0
Leg fat-free mass (left)	2.3	12.2	15.1	-3.6	-3.0	-3.4	3.0	-3.5	-3.4	-3.6	-3.9	-3.8	-3.5	-3.8	-3.6	-2.6	-3.2	-3.9	-3.7	-3.0	-3.5	-3.7	-3.5	-3.7	-3.6	-3.6
Diverticular disease/diverticulitis (self-reported)	2.3	2.8	5.0	-1.3	-1.9	-1.5	1.5	-1.8	-1.8	-2.0	-2.2	-2.2	-1.6	-1.7	-1.8	-0.9	-1.4	-2.0	-1.8	-0.9	-0.2	-1.9	-1.6	-1.7	-1.8	-1.6
Leg predicted mass (left)	2.3	12.1	14.6	-3.6	-3.0	-3.3	3.0	-3.4	-3.4	-3.6	-3.8	-3.8	-3.5	-3.8	-3.6	-2.7	-3.2	-3.8	-3.7	-3.0	-3.5	-3.7	-3.5	-3.6	-3.6	-3.5
Mean time to correctly identify matches	2.3	4.5	10.8	-2.1	-1.2	-2.4	0.4	-3.3	-1.9	-1.9	-2.7	-1.7	-2.4	-2.1	-2.5	-1.1	-1.3	-2.4	-1.9	-1.1	-3.1	-1.9	-2.1	-2.4	-2.3	-2.1
Medication: Aspirin	2.3	3.0	5.0	1.6	1.8	1.9	-0.3	2.2	1.6	1.8	1.9	1.9	2.0	1.9	1.9	1.9	1.3	1.8	1.7	1.1	1.9	1.6	1.8	1.8	1.8	1.7
Heart attack/myocardial infarction (self-reported)	2.3	3.0	3.9	1.9	1.7	1.9	1.1	1.5	1.7	1.4	1.5	1.4	1.7	1.9	1.6	1.7	2.0	1.6	1.7	1.8	1.8	1.9	1.9	1.9	1.8	1.8
Alcohol intake frequency.	2.2	5.0	9.3	-2.6	-1.3	-2.4	-1.0	-1.9	-2.2	-2.0	-2.1	-1.4	-2.0	-2.2	-2.1	-2.0	-2.5	-2.3	-2.4	-2.7	-3.0	-2.6	-2.2	-2.5	-2.4	-2.5
Comparative height size at age 10	2.2	12.2	19.5	-3.2	-3.2	-3.4	3.7	-4.4	-3.4	-3.6	-4.3	-4.1	-3.6	-3.7	-4.0	-2.3	-2.4	-4.1	-3.5	-2.1	-3.0	-3.5	-3.4	-3.5	-3.6	-3.4
Guilty feelings	2.2	3.4	15.2	1.7	1.8	1.7	-3.9	2.4	1.5	1.6	2.1	1.5	1.7	1.8	1.6	1.2	1.2	1.9	1.7	0.9	1.5	1.5	1.6	1.9	1.7	1.7
Primary Biliary Cirrhosis	2.1	3.0	5.3	1.8	1.8	1.8	-2.2	1.2	1.9	2.0	1.1	1.6	1.8	1.6	1.6	2.3	2.0	1.4	2.0	1.7	1.1	1.6	1.8	1.6	1.6	1.8
Number of children fathered	2.1	2.3	3.3	1.8	1.5	1.6	-0.5	1.2	1.8	1.4	1.4	1.6	1.5	1.8	1.5	1.7	1.5	1.4	1.5	1.5	1.3	1.7	1.7	1.5	1.6	1.6
Neck or shoulder pain in last month	2.1	2.9	7.3	-2.2	-1.6	-1.9	-0.9	-0.8	-1.5	-1.8	-0.8	-1.3	-1.7	-1.6	-1.3	-2.7	-2.2	-1.2	-1.9	-2.2	-1.7	-1.9	-1.8	-1.5	-1.7	-1.9
Eye problems/disorders: Cataract	2.1	2.4	8.4	-1.5	-1.2	-1.4	2.9	-1.8	-1.6	-1.4	-1.7	-1.7	-1.4	-1.6	-1.6	-0.8	-1.2	-1.6	-1.4	-0.9	-0.9	-1.6	-1.5	-1.5	-1.5	-1.4
Age started oral contraceptive pill	2.1	2.7	4.2	-1.5	-1.9	-1.6	-0.7	-2.0	-1.9	-1.7	-2.0	-1.9	-1.8	-1.6	-1.8	-1.0	-1.2	-2.0	-1.7	-1.0	-1.0	-1.6	-1.6	-1.7	-1.7	-1.7
Illnesses of father: High blood pressure	2.0	2.5	5.6	1.2	2.2	1.3	-0.4	1.8	1.3	2.2	2.0	2.4	1.7	1.7	1.7	1.6	0.7	1.8	1.9	0.6	0.6	1.4	1.5	1.3	1.5	1.4
Severe depression (siblings)	1.9	2.2	3.6	1.2	1.7	1.5	-1.2	1.5	1.3	1.3	1.4	1.9	1.7	1.5	1.6	1.2	1.5	1.5	1.3	1.5	0.9	1.5	1.7	1.4	1.5	1.5
Heart attack	1.9	2.5	3.2	1.8	1.5	1.8	0.8	1.5	1.5	1.4	1.4	1.3	1.5	1.7	1.4	1.5	1.7	1.6	1.6	1.5	1.7	1.7	1.7	1.8	1.7	1.7
Allergy	1.9	4.3	5.7	2.2	1.8	2.3	-0.0	2.3	2.0	1.9	2.2	2.1	2.2	2.3	2.4	1.7	2.1	2.2	2.0	1.7	2.3	2.2	2.2	2.3	2.3	2.2
Alcohol intake versus 10 years previously	1.9	2.8	4.7	-1.7	-1.1	-1.5	1.7	-1.6	-1.8	-1.4	-2.2	-1.2	-1.5	-1.6	-1.6	-0.7	-1.6	-2.1	-1.7	-1.9	-1.5	-2.1	-1.6	-2.0	-1.9	-1.9
Health satisfaction	1.9	2.4	6.7	-1.4	-1.1	-1.6	-2.6	-0.3	-1.4	-1.2	-0.4	-0.6	-1.2	-1.2	-1.0	-2.3	-2.4	-0.9	-1.6	-2.5	-1.8	-1.7	-1.4	-1.5	-1.4	-1.7
Ever depressed for a whole week	1.9	2.3	3.6	1.6	1.4	1.6	-1.0	1.5	1.2	1.9	1.5	1.2	1.6	1.5	1.4	1.4	1.6	1.6	1.9	1.3	1.4	1.6	1.4	1.7	1.6	1.6
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	8.3	-1.2	-2.0	-1.4	-1.7	0.2	-1.9	-1.5	0.0	-1.5	-1.6	-1.2	-1.0	-2.9	-2.0	-0.6	-1.4	-2.4	-1.0	-1.4	-1.6	-0.8	-1.1	-1.5
Reaction Time	1.8	3.5	9.3	-1.8	-0.9	-2.2	-0.3	-3.0	-1.6	-1.5	-2.4	-1.2	-2.1	-1.8	-2.3	-0.7	-1.2	-2.1	-1.6	-0.9	-3.0	-1.6	-1.8	-2.2	-2.0	-1.9
Worrier / anxious feelings	1.8	3.5	30.4	1.3	2.3	1.5	-5.5	1.9	1.1	1.4	1.4	2.2	1.8	1.7	1.6	1.7	1.1	1.4	1.3	0.8	0.5	1.2	1.7	1.3	1.4	1.4
Age at last live birth	1.8	2.6	5.2	-1.8	-1.6	-1.4	0.3	-1.4	-1.6	-2.3	-1.6	-1.5	-1.5	-1.5	-1.4	-2.0	-1.5	-1.8	-2.2	-1.4	-1.1	-1.8	-1.4	-1.6	-1.6	-1.7
Handedness (chirality/laterality): Left-handed	1.8	2.2	3.8	-1.6	-1.1	-1.6	-0.2	-1.9	-1.5	-1.7	-1.6	-1.2	-1.6	-1.5	-1.6	-1.5	-1.2	-1.5	-1.5	-0.7	-1.6	-1.5	-1.4	-1.6	-1.6	-1.5
Commuting to job workplace: Public transport	1.8	2.1	4.2	-1.2	-2.0	-1.4	1.5	-1.2	-1.5	-1.7	-1.1	-1.8	-1.7	-1.6	-1.4	-1.7	-1.1	-1.2	-1.5	-1.0	-1.2	-1.3	-1.6	-1.2	-1.3	-1.4
Heart disease (siblings)	1.8	2.3	3.1	1.3	1.6	1.7	0.6	1.3	1.6	1.3	1.5	1.6	1.6	1.6	1.6	1.8	1.4	1.5	1.4	1.4	1.2	1.7	1.6	1.6	1.6	1.6
Lung FVC	1.7	8.5	16.8	-3.4	-1.8	-3.7	-2.1	-2.1	-2.5	-1.5	-1.9	-1.2	-2.9	-2.7	-2.8	-2.9	-4.1	-2.5	-2.5	-4.0	-3.4	-3.4	-3.3	-3.4	-3.3	-3.5
Hand grip strength (left)	1.7	4.5	14.4	2.2	1.9	2.2	-3.8	2.1	2.0	1.7	1.8	1.7	2.0	2.0	1.8	2.1	2.2	1.9	1.9	2.1	1.7	2.3	2.2	2.0	2.2	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	5.9	1.4	0.8	1.3	-2.0	2.4	1.2	0.7	2.3	1.0	1.1	1.5	1.6	-0.5	0.7	1.9	1.0	0.3	1.4	1.4	1.2	1.8	1.5	1.3
Medication: Aspirin	1.7	2.2	4.0	1.3	1.7	1.7	-0.1	1.8	1.4	1.6	1.3	1.6	1.8	1.6	1.6	2.0	1.2	1.4	1.4	1.0	1.6	1.3	1.6	1.4	1.5	1.5
Prostate Cancer	1.6	2.3	3.0	1.5	1.4	1.5	0.5	1.6	1.5	1.7	1.4	1.7	1.6	1.6	1.5	1.3	1.5	1.5	1.6	1.4	1.5	1.7	1.6	1.5	1.6	1.6
Bipolar Disorder (2011)	1.6	1.5	2.9	-1.2	-1.3	-1.1	-1.0	-0.8	-1.2	-1.1	-0.9	-1.1	-1.3	-1.4	-1.1	-1.3	-1.5	-1.2	-1.4	-1.7	0.0	-1.4	-1.3	-1.4	-1.2	-1.3
Pain all over the body in last month	1.6	1.7	3.2	-1.2	-1.3	-1.3	-1.4	-0.8	-1.4	-1.2	-1.0	-1.2	-1.3	-1.2	-1.3	-1.4	-1.7	-1.2	-1.4	-1.8	-0.9	-1.5	-1.4	-1.3	-1.4	-1.5
Gout (self-reported)	1.6	2.2	3.1	1.6	1.4	1.7	-0.2	1.8	1.7	1.7	1.4	1.1	1.6	1.5	1.5	1.6	1.3	1.4	1.6	0.9	1.5	1.4	1.4	1.6	1.5	1.5
Whole body fat-free mass	1.6	9.1	14.7	-2.9	-2.6	-2.7	3.8	-3.1	-2.8	-3.3	-3.7	-3.6	-3.0	-3.3	-3.2	-2.0	-2.3	-3.5	-3.2	-2.0	-2.4	-3.1	-2.9	-3.0	-3.1	-2.9
Whole body water mass	1.6	8.9	14.9	-2.9	-2.6	-2.7	3.9	-3.0	-2.8	-3.3	-3.6	-3.6	-2.9	-3.2	-3.1	-2.0	-2.3	-3.4	-3.1	-2.0	-2.4	-3.1	-2.9	-3.0	-3.0	-2.9
Ever had prostate specific antigen (PSA) test	1.6	1.8	2.9	-1.2	-1.4	-1.2	1.5	-1.6	-1.3	-1.7	-1.4	-1.4	-1.5	-1.4	-1.4	-1.2	-0.9	-1.5	-1.5	-0.7	-1.4	-1.2	-1.2	-1.4	-1.3	-1.3
Schizophrenia (2018)	1.5	3.1	5.4	-2.0	-1.5	-2.0	-0.1	-1.0	-1.4	-1.6	-1.2	-1.2	-1.8	-1.7	-1.6	-2.0	-2.3	-1.5	-1.9	-2.3	-2.3	-2.0	-1.8	-1.9	-1.9	-2.0
Average weekly fortified wine intake	1.5	1.7	6.3	0.9	1.2	1.2	-2.5	1.4	1.2	1.4	1.3	1.7	1.5	1.2	1.5	1.3	0.6	1.3	1.2	0.8	1.0	1.0	1.3	1.0	1.2	1.2
Forced vital capacity (FVC)	1.5	5.9	8.2	-2.9	-1.9	-2.7	0.4	-2.6	-2.5	-2.1	-2.6	-2.3	-2.5	-2.6	-2.7	-1.9	-2.4	-2.7	-2.4	-2.1	-2.0	-2.6	-2.7	-2.7	-2.7	-2.7
Pulse wave reflection index	1.5	1.8	3.9	-1.6	-1.0	-1.5	1.1	-0.9	-1.3	-1.2	-0.7	-0.8	-1.4	-1.3	-1.1	-2.0	-1.7	-1.0	-1.4	-1.7	-1.5	-1.4	-1.4	-1.4	-1.3	-1.5
Forced vital capacity (FVC), Best measure	1.5	5.6	7.6	-2.6	-1.8	-2.6	0.8	-2.6	-2.3	-2.1	-2.6	-2.2	-2.5	-2.5	-2.6	-1.9	-2.4	-2.6	-2.4	-1.9	-1.9	-2.6	-2.6	-2.8	-2.6	-2.6
Shortness of breath walking on level ground	1.5	1.7	3.3	1.2	1.5	1.2	0.1	1.6	1.6	1.7	1.8	1.4	1.3	1.4	1.4	0.9	0.7	1.7	1.6	0.6	0.5	1.4	1.2	1.4	1.4	1.3
Supplements: Vitamin C	1.5	1.8	3.7	-1.1	-1.6	-1.1	0.8	-1.6	-1.6	-1.2	-1.7	-1.9	-1.5	-1.6	-1.5	-0.7	-0.8	-1.6	-1.2	-1.0	-1.3	-1.3	-1.4	-1.3	-1.3	-1.3
Medication: Blood pressure	1.5	2.8	5.1	1.4	2.3	1.6	-1.7	1.7	1.6	1.6	1.6	2.2	1.9	2.0	1.8	1.7	1.3	1.6	1.5	1.0	1.1	1.6	1.8	1.6	1.6	1.6
Basal metabolic rate	1.5	8.2	12.4	-2.8	-2.3	-2.6	3.1	-3.0	-2.7	-3.1	-3.5	-3.3	-2.8	-3.1	-3.0	-1.9	-2.3	-3.4	-3.1	-2.0	-2.4	-3.0	-2.8	-3.0	-3.0	-2.8
Unable to work because of sickness or disability	1.5	2.0	2.7	-1.5	-1.3	-1.5	-1.6	-1.3	-1.5	-1.5	-1.3	-1.4	-1.4	-1.5	-1.4	-1.6	-1.3	-1.3	-1.4	-1.2	-1.5	-1.6	-1.4	-1.3	-1.5	-1.4
Lupus	1.4	2.1	6.3	1.7	0.9	1.4	-0.2	1.7	1.3	1.0	2.0	1.0	1.2	1.6	1.4	0.3	1.0	1.8	1.2	1.3	2.5	1.7	1.4	1.7	1.6	1.4
Medication: Simvastatin	1.4	2.1	3.1	1.6	1.7	1.4	-1.1	1.5	1.1	1.6	1.3	1.8	1.5	1.6	1.3	1.5	1.6	1.3	1.5	1.2	1.1	1.4	1.6	1.4	1.4	1.5
Trunk fat-free mass	1.4	8.3	17.5	-2.7	-2.5	-2.5	4.2	-3.0	-2.6	-3.3	-3.6	-3.6	-2.8	-3.1	-3.0	-1.9	-2.0	-3.3	-3.0	-1.6	-1.9	-2.9	-2.7	-2.8	-2.9	-2.7
Trunk predicted mass	1.4	8.0	17.6	-2.6	-2.5	-2.4	4.2	-3.0	-2.6	-3.3	-3.6	-3.6	-2.7	-3.0	-3.0	-1.9	-1.9	-3.3	-3.0	-1.5	-1.9	-2.8	-2.7	-2.8	-2.8	-2.6
Pulse wave peak to peak time	1.4	1.6	4.5	1.2	1.5	1.4	-0.2	0.5	1.4	0.8	0.3	1.4	1.5	1.2	1.2	1.6	1.9	0.7	0.9	2.1	1.3	1.3	1.5	1.0	1.1	1.3
Osteoarthritis (self-reported)	1.4	1.8	4.0	-1.2	-1.1	-1.3	0.7	-0.6	-1.5	-1.6	-0.8	-1.3	-1.2	-1.1	-1.0	-2.0	-1.9	-1.1	-1.7	-2.0	-0.8	-1.6	-1.4	-1.1	-1.3	-1.5
Financial difficulties in last 2 years	1.3	1.7	4.4	-1.1	-0.8	-1.1	-1.1	-1.6	-1.4	-1.4	-2.1	-1.3	-1.1	-1.3	-1.5	-0.4	-0.7	-1.8	-1.4	-0.6	-1.2	-1.4	-1.1	-1.5	-1.4	-1.3
Hip circumference	1.3	5.8	9.0	-2.5	-1.7	-2.4	1.4	-2.5	-2.5	-2.6	-3.0	-2.5	-2.3	-2.5	-2.5	-1.5	-2.2	-2.9	-2.7	-2.0	-1.9	-2.8	-2.4	-2.7	-2.7	-2.5
Time employed in main current job	1.3	1.5	2.8	1.3	1.7	1.1	-1.1	0.8	1.3	1.3	1.0	1.5	1.1	1.4	1.0	1.3	1.3	1.0	1.3	1.1	0.7	1.4	1.2	1.0	1.2	1.2
Father’s age at death	1.3	1.7	3.3	-1.3	-0.7	-1.3	1.4	-1.8	-0.8	-1.0	-1.8	-0.8	-1.2	-1.3	-1.2	-0.5	-1.0	-1.6	-1.2	-1.0	-1.7	-1.4	-1.2	-1.6	-1.5	-1.3
Blood clot in the leg (DVT)	1.3	1.7	2.6	-1.3	-1.5	-1.3	-0.4	-1.4	-1.1	-0.7	-1.6	-1.5	-1.3	-1.4	-1.6	-0.3	-1.2	-1.5	-1.0	-1.0	-1.3	-1.4	-1.4	-1.5	-1.4	-1.3
Mood swings	1.3	2.3	12.8	1.1	1.6	1.2	-3.6	2.2	1.1	1.1	1.9	1.3	1.4	1.6	1.4	0.5	0.7	1.7	1.2	0.6	0.8	1.2	1.3	1.6	1.4	1.3
Blood Platelet Count	1.2	13.4	21.6	-3.5	-3.3	-3.8	1.7	-4.7	-3.5	-3.8	-4.3	-3.8	-3.8	-3.9	-4.0	-2.5	-3.1	-4.3	-3.9	-2.7	-3.5	-3.7	-3.8	-4.0	-3.9	-3.8
Hand grip strength (right)	1.2	3.2	8.1	2.0	1.5	1.9	-2.9	1.6	1.8	1.6	1.5	1.3	1.7	1.7	1.5	1.7	1.9	1.6	1.7	1.7	1.5	1.9	1.7	1.8	1.9	1.8
Serious illness, injury or assault to yourself	1.2	1.4	2.2	-1.1	-0.9	-1.3	0.5	-1.0	-1.5	-0.8	-1.1	-0.9	-1.0	-1.2	-1.2	-0.9	-1.4	-1.3	-1.1	-1.4	-1.5	-1.4	-1.2	-1.4	-1.3	-1.3
Waist circumference	1.2	4.4	5.8	-2.3	-1.2	-2.3	-0.7	-2.1	-2.0	-2.3	-2.4	-1.7	-2.1	-2.0	-2.2	-1.7	-2.1	-2.3	-2.4	-1.8	-2.1	-2.3	-2.0	-2.4	-2.3	-2.3
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	5.4	-2.3	-1.7	-2.2	0.8	-2.3	-2.1	-1.6	-2.2	-2.0	-2.1	-2.2	-2.2	-1.3	-2.0	-2.2	-1.9	-1.8	-1.8	-2.2	-2.2	-2.3	-2.2	-2.2
Pulse wave Arterial Stiffness index	1.2	1.4	3.8	-1.1	-1.4	-1.2	0.4	-0.4	-1.2	-0.7	-0.3	-1.4	-1.4	-1.1	-1.1	-1.4	-1.7	-0.7	-0.8	-1.9	-1.1	-1.2	-1.4	-0.9	-1.0	-1.2
Hair/balding pattern: Pattern 4	1.2	3.0	4.9	-1.6	-2.2	-1.7	-0.1	-1.2	-2.0	-1.5	-1.3	-2.2	-1.9	-1.9	-1.8	-1.7	-2.0	-1.6	-1.6	-2.1	-1.1	-1.9	-2.0	-1.6	-1.7	-1.8
Back pain experienced in last month	1.2	1.8	3.7	1.5	1.1	1.4	-0.4	1.8	1.2	0.9	1.5	1.3	1.5	1.6	1.5	0.3	1.0	1.4	1.0	0.9	1.9	1.4	1.5	1.5	1.4	1.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	4.6	-1.2	-0.9	-1.3	-1.2	-0.9	-0.7	-1.6	-0.7	-0.8	-1.2	-1.1	-0.9	-2.1	-1.3	-0.9	-1.5	-1.1	-0.9	-1.3	-1.1	-1.1	-1.2	-1.2
Pain type(s) experienced in last month: Hip pain	1.2	1.6	4.1	0.9	1.2	1.3	-1.9	1.3	1.1	1.1	1.0	1.1	1.4	1.3	1.3	1.0	1.2	1.0	1.0	1.2	2.0	1.1	1.3	1.2	1.2	1.2
Impedance of whole body	1.2	5.9	20.6	2.5	2.3	2.2	-4.5	1.8	2.2	2.3	2.2	2.6	2.3	2.5	2.2	2.2	2.3	2.3	2.3	2.2	1.9	2.5	2.4	2.3	2.4	2.4
Bipolar Disorder or Schizophrenia	1.1	2.8	4.8	-1.9	-1.5	-1.8	-1.0	-1.5	-1.3	-1.6	-1.6	-1.0	-1.7	-1.7	-1.6	-1.5	-1.5	-1.8	-1.9	-1.8	-2.2	-1.8	-1.7	-1.9	-1.8	-1.9
Triglycerides	1.1	1.9	3.2	1.3	1.4	1.3	-0.8	1.7	1.0	1.6	1.6	1.3	1.3	1.3	1.5	1.1	1.2	1.7	1.8	1.0	1.0	1.4	1.3	1.5	1.4	1.5
Hayfever, allergic rhinitis or eczema	1.1	2.4	3.4	-1.7	-1.3	-1.6	1.4	-1.9	-1.5	-1.1	-1.7	-1.4	-1.4	-1.8	-1.7	-0.7	-1.5	-1.8	-1.3	-1.3	-1.6	-1.8	-1.6	-1.8	-1.7	-1.7
Weight	1.1	5.3	8.5	-2.5	-1.4	-2.3	0.5	-2.4	-2.2	-2.3	-2.9	-2.2	-2.2	-2.4	-2.4	-1.4	-2.1	-2.8	-2.5	-1.9	-2.4	-2.6	-2.3	-2.6	-2.6	-2.4
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.8	-1.1	-0.8	-1.0	1.4	-1.6	-1.0	-1.2	-1.7	-1.3	-1.1	-1.1	-1.4	-0.1	-0.5	-1.5	-1.1	-0.3	-0.8	-1.0	-1.1	-1.2	-1.1	-1.0
Birth weight of first child	1.1	2.0	4.7	-1.5	-1.1	-1.4	0.2	-2.1	-1.4	-0.9	-2.2	-1.2	-1.4	-1.5	-1.7	0.1	-0.9	-2.0	-1.2	-1.0	-1.2	-1.7	-1.4	-1.8	-1.6	-1.5
Migraine (self-reported)	1.1	1.3	3.5	1.0	1.0	1.2	-1.9	1.4	1.2	1.0	1.3	1.4	1.2	1.3	1.2	0.6	0.9	1.2	0.9	0.7	1.0	1.1	1.2	1.1	1.2	1.1
Smoking status: Previous	1.1	1.6	4.1	1.3	1.1	1.3	-2.0	0.8	1.0	1.4	0.7	1.2	1.1	1.4	0.9	1.9	1.6	0.9	1.5	1.4	1.0	1.4	1.3	1.2	1.2	1.3
Ever taken oral contraceptive pill	1.1	1.2	3.4	1.4	0.8	1.2	1.7	1.2	0.9	0.7	1.0	0.6	1.1	1.2	1.0	0.9	1.0	1.0	0.9	0.9	1.8	1.1	1.0	1.2	1.1	1.1
Ovarian Cancer	1.0	1.4	3.8	0.7	1.1	1.2	2.0	1.6	1.2	1.8	1.5	1.6	1.1	1.0	1.2	1.2	0.3	1.3	1.4	-0.3	-0.2	0.7	0.9	0.8	1.0	0.8
Crohns Disease (2012)	1.0	1.5	2.6	1.6	1.2	1.3	0.1	0.9	1.4	1.4	0.6	1.0	1.2	1.3	1.1	1.6	1.6	0.9	1.3	1.3	1.4	1.4	1.3	1.2	1.3	1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.9	-1.3	-0.0	-1.0	-0.3	-1.9	-0.2	-1.0	-2.0	-0.5	-0.7	-1.2	-1.1	0.2	-0.3	-1.6	-1.0	-0.2	-1.7	-1.0	-0.8	-1.4	-1.3	-1.0
Height	1.0	20.2	37.8	-3.2	-4.3	-4.0	3.8	-5.7	-4.7	-5.5	-6.2	-5.7	-4.8	-4.6	-5.3	-2.9	-2.3	-5.7	-5.0	-1.9	-2.7	-4.3	-4.2	-4.5	-4.5	-4.3
Cardiovascular Disease	1.0	3.4	4.7	1.9	1.9	2.0	-1.7	2.1	1.7	1.3	2.1	1.9	1.9	2.2	2.0	1.4	1.6	1.9	1.5	1.3	1.5	2.0	2.1	2.0	2.0	1.9
Arm fat percentage (right)	1.0	4.1	10.1	-2.2	-0.9	-2.1	-3.2	-1.6	-1.9	-1.6	-1.8	-1.0	-1.8	-1.8	-1.8	-1.6	-2.4	-1.9	-2.0	-2.4	-2.5	-2.2	-1.9	-2.2	-2.1	-2.1
Ever highly irritable/argumentative for 2 days	1.0	1.2	7.1	-0.7	-0.8	-0.8	-1.8	0.9	-0.7	-0.0	0.6	-0.4	-0.7	-0.7	-0.3	-1.8	-2.1	-0.1	-0.5	-2.7	-1.2	-1.0	-1.1	-0.6	-0.7	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	3.0	1.2	1.1	1.0	-0.3	0.5	1.0	1.7	0.6	1.0	1.0	1.0	0.7	1.6	1.5	0.9	1.7	1.5	0.6	1.2	1.0	0.9	1.0	1.2
Qualifications: nursing, teaching	1.0	1.6	4.5	-1.2	-2.1	-1.1	0.1	-1.2	-1.5	-1.2	-1.1	-2.1	-1.5	-1.5	-1.4	-0.9	-0.9	-1.1	-1.0	-0.8	-1.1	-1.1	-1.4	-0.9	-1.1	-1.0
Medication for hormone replacement therapy	0.9	1.0	2.2	1.0	1.4	0.8	-1.4	0.5	0.9	1.5	0.6	1.4	0.9	1.0	0.7	1.4	1.2	0.7	1.1	0.9	0.6	1.0	0.9	0.7	0.9	0.9
Mouth/teeth dental problems	0.9	1.3	4.2	0.9	1.0	1.2	1.4	0.3	1.0	0.5	0.7	0.9	1.0	1.0	1.2	1.1	1.7	1.0	1.0	2.0	1.1	1.4	1.3	1.2	1.2	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	4.2	-1.8	-1.4	-1.8	1.3	-2.1	-1.8	-1.4	-2.0	-1.8	-1.8	-1.9	-2.0	-0.9	-1.7	-2.0	-1.6	-1.4	-1.3	-1.8	-1.9	-2.0	-1.9	-1.8
Chronic bronchitis/emphysema (mother)	0.9	1.0	16.3	0.6	0.5	0.5	-4.0	0.3	0.4	0.1	-0.1	0.1	0.6	0.6	0.3	0.6	0.7	0.2	0.3	1.0	1.3	0.4	0.6	0.5	0.3	0.5
Knee pain experienced in last month	0.9	1.5	3.6	-1.3	-0.6	-1.3	-1.9	-1.0	-0.8	-1.6	-1.2	-0.8	-1.1	-1.1	-1.1	-1.2	-1.1	-1.3	-1.6	-0.9	-0.7	-1.3	-1.1	-1.3	-1.3	-1.3
Illnesses of father: Heart disease	0.9	1.3	2.1	1.0	1.1	1.1	-0.8	1.3	0.8	1.3	1.4	1.2	1.1	1.2	1.2	0.8	1.0	1.4	1.3	0.7	0.9	1.3	1.1	1.3	1.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	3.8	-1.3	-1.6	-1.2	1.6	-1.4	-1.4	-1.2	-1.5	-1.9	-1.5	-1.6	-1.6	-0.8	-1.0	-1.4	-1.1	-0.7	-0.6	-1.3	-1.5	-1.4	-1.3	-1.3
Medication: Atorvastatin	0.9	1.1	2.6	0.9	1.6	1.0	0.5	1.1	1.2	0.7	0.9	1.5	1.3	1.1	1.2	0.8	0.7	1.0	0.7	0.9	1.1	0.8	1.2	0.8	0.9	0.9
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	1.9	-1.1	-1.4	-1.1	-0.2	-1.1	-0.9	-0.6	-1.3	-1.3	-1.1	-1.2	-1.3	-0.3	-1.1	-1.2	-0.8	-1.0	-1.0	-1.1	-1.1	-1.2	-1.2	-1.1
Frequency of depressed mood in last 2 weeks	0.8	1.2	12.1	0.7	1.3	0.9	-3.5	0.9	0.9	0.2	0.8	0.7	0.8	0.9	0.9	0.7	0.8	0.9	0.6	0.7	-0.2	0.8	1.0	1.0	0.9	0.9
Age when periods started (menarche)	0.8	2.0	3.9	1.4	1.4	1.6	-1.6	1.1	1.3	0.9	0.9	0.9	1.3	1.4	1.2	1.4	2.0	1.2	1.3	1.8	1.3	1.6	1.5	1.6	1.5	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	5.5	-1.1	-0.7	-1.2	-2.3	-0.9	-1.2	-1.2	-1.2	-1.0	-1.0	-0.9	-1.2	-1.0	-1.0	-1.1	-1.2	-1.0	-1.2	-1.1	-1.0	-1.0	-1.1	-1.1
Standing height	0.8	8.4	17.4	-2.4	-2.5	-2.4	3.1	-3.9	-2.8	-3.4	-4.2	-3.8	-2.9	-3.1	-3.4	-1.3	-1.4	-3.7	-3.0	-1.0	-2.0	-2.7	-2.6	-2.9	-2.9	-2.6
Loud music exposure frequency	0.8	0.8	1.8	-0.6	-1.2	-0.8	-0.7	-0.9	-0.9	-1.0	-0.9	-1.3	-1.0	-0.9	-1.0	-0.8	-0.9	-1.0	-0.9	-0.8	-0.6	-0.9	-0.9	-0.8	-0.9	-0.9
Comparative body size at age 10	0.8	2.2	3.8	-1.9	-1.1	-1.7	0.5	-1.8	-1.5	-0.4	-1.5	-1.1	-1.5	-1.7	-1.7	-0.7	-1.3	-1.6	-1.0	-1.5	-2.0	-1.5	-1.8	-1.8	-1.6	-1.7
Arm fat percentage (left)	0.8	3.2	9.6	-2.0	-0.6	-1.9	-3.1	-1.3	-1.6	-1.2	-1.5	-0.7	-1.5	-1.5	-1.5	-1.3	-2.1	-1.7	-1.7	-2.2	-2.4	-2.0	-1.6	-2.0	-1.9	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	10.0	-0.7	-1.3	-0.6	-3.2	-0.4	-0.9	-0.8	-0.6	-1.2	-0.8	-0.8	-0.8	-0.7	-0.5	-0.6	-0.7	-0.4	-0.2	-0.5	-0.8	-0.4	-0.6	-0.6
Arm fat mass (left)	0.8	3.3	5.1	-2.0	-0.9	-1.9	-1.6	-1.7	-1.7	-1.7	-2.0	-1.3	-1.7	-1.8	-1.8	-1.3	-1.9	-2.0	-2.0	-1.9	-2.3	-2.1	-1.8	-2.1	-2.0	-2.0
Miserableness	0.8	1.5	2.3	1.1	1.3	1.4	-1.5	1.5	1.1	0.8	1.1	1.0	1.3	1.3	1.3	1.2	1.2	1.2	1.0	0.9	0.8	1.2	1.3	1.4	1.3	1.3
Mother’s age at death	0.8	1.0	1.5	-0.8	-1.2	-1.1	0.0	-1.1	-0.8	-0.8	-1.1	-0.9	-1.2	-1.0	-1.2	-0.7	-0.8	-1.0	-0.8	-0.8	-1.1	-1.0	-1.1	-1.1	-1.1	-1.0
Medication: Lisinopril	0.8	1.1	2.1	0.8	1.1	1.1	1.0	0.8	0.8	1.2	0.8	1.0	1.2	1.1	0.9	1.4	1.0	0.8	1.1	1.0	1.4	0.9	1.1	1.0	1.0	1.0
Alzheimer’s Disease (including proxy)	0.7	1.0	3.0	-0.7	-1.3	-0.9	1.7	-0.1	-0.8	-0.7	-0.2	-1.1	-1.1	-0.9	-0.7	-1.4	-1.3	-0.5	-0.8	-1.7	-1.0	-1.0	-1.1	-0.6	-0.8	-1.0
Sensitivity / hurt feelings	0.7	1.2	2.4	1.0	1.3	1.0	-1.5	1.5	0.8	0.5	1.3	1.2	1.2	1.2	1.2	0.2	0.6	1.2	0.7	0.9	1.3	1.0	1.2	1.1	1.0	1.0
Diabetes (father)	0.7	0.8	1.7	-1.1	-0.7	-1.1	-0.3	-0.7	-0.9	-0.9	-0.7	-0.7	-0.9	-0.9	-0.9	-1.3	-1.0	-0.8	-0.9	-0.9	-1.2	-1.1	-0.9	-0.9	-1.0	-0.9
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.8	-1.2	-0.9	-1.0	0.3	-0.5	-1.0	-0.4	-0.6	-0.8	-0.8	-1.1	-0.8	-0.7	-1.3	-0.8	-0.7	-1.3	-0.9	-1.1	-1.1	-1.0	-1.0	-1.1
Medication: Ramipril	0.7	0.9	1.8	1.0	1.1	0.9	0.6	1.1	1.0	0.5	1.2	1.3	1.1	1.1	1.2	0.2	0.8	1.2	0.6	0.7	0.3	1.0	1.1	1.1	1.0	1.0
Arm fat mass (right)	0.7	2.9	4.0	-1.9	-0.8	-1.8	-1.7	-1.5	-1.6	-1.6	-1.8	-1.2	-1.5	-1.6	-1.7	-1.3	-1.8	-1.9	-1.8	-1.8	-2.0	-2.0	-1.6	-2.0	-1.9	-1.8
Family relationship satisfaction	0.7	0.9	1.9	1.0	1.4	0.8	-1.2	1.2	0.9	1.2	1.0	1.3	1.0	0.9	1.0	0.9	0.5	0.9	1.0	0.3	0.4	0.7	0.9	0.8	0.8	0.8
Eye problems/disorders: Glaucoma	0.7	0.9	8.0	0.8	1.1	0.5	-2.8	-0.2	1.0	0.8	0.1	0.9	0.4	0.7	0.2	0.9	1.3	0.4	0.8	1.2	0.2	0.8	0.7	0.5	0.6	0.6
Arm fat-free mass (left)	0.7	3.6	9.0	-1.7	-1.4	-1.5	3.0	-2.0	-1.6	-2.2	-2.6	-2.3	-1.7	-2.0	-1.9	-1.0	-1.1	-2.4	-2.1	-0.9	-1.3	-1.9	-1.7	-1.9	-1.9	-1.7
Number of operations (self-reported)	0.7	1.0	1.7	-1.2	-0.7	-1.2	-1.0	-0.8	-0.9	-0.9	-1.0	-0.4	-0.9	-0.9	-1.1	-0.9	-1.1	-1.1	-1.1	-1.1	-0.9	-1.3	-0.9	-1.2	-1.2	-1.2
Intelligence (Savage-Jansen 2018)	0.6	2.0	4.8	-1.5	-1.2	-1.2	2.2	-1.9	-1.2	-1.3	-2.1	-1.3	-1.2	-1.5	-1.6	-0.4	-0.5	-1.7	-1.3	-0.4	-1.0	-1.4	-1.3	-1.5	-1.5	-1.3
Verbal and Numeric Reasoning (VNR)	0.6	1.3	10.0	-0.7	-0.7	-0.3	3.2	-1.9	-0.5	-0.8	-2.0	-1.0	-0.5	-1.0	-1.1	1.1	0.6	-1.4	-0.6	1.0	-0.3	-0.5	-0.5	-0.9	-0.7	-0.4
Breast Cancer	0.6	1.5	2.4	1.5	1.4	1.3	-0.9	1.2	0.8	1.0	1.2	1.1	1.4	1.3	1.3	1.2	1.2	1.3	1.0	1.3	1.1	1.2	1.5	1.3	1.4	1.3
Fasting Glucose	0.6	0.7	2.2	-0.7	-0.2	-0.8	1.4	-0.4	-1.0	-0.5	-0.2	-0.3	-0.8	-0.7	-0.6	-1.0	-1.2	-0.5	-0.8	-1.4	-1.5	-0.8	-0.8	-0.8	-0.7	-0.8
BMI	0.6	3.3	6.7	-2.3	-0.6	-2.0	-1.0	-1.1	-1.7	-1.5	-1.5	-0.7	-1.5	-1.8	-1.4	-1.9	-2.4	-1.7	-1.9	-2.5	-2.6	-2.2	-1.8	-2.1	-2.0	-2.0
Qualifications: CSEs or equivalent	0.6	0.8	2.8	-1.0	-0.0	-1.0	-0.9	-0.1	-0.8	-0.7	-0.2	-0.3	-0.6	-0.6	-0.5	-1.5	-1.5	-0.6	-1.0	-1.7	-1.0	-1.1	-0.9	-0.8	-0.9	-1.0
Trunk fat mass	0.6	2.5	5.5	-1.6	-0.4	-1.6	-2.3	-1.6	-1.3	-1.3	-1.9	-0.8	-1.3	-1.4	-1.5	-0.7	-1.5	-1.9	-1.7	-1.5	-1.9	-1.8	-1.3	-1.9	-1.7	-1.7
Medication: Cholesterol lowering	0.6	1.0	1.8	1.2	1.3	1.0	0.5	1.0	1.0	1.0	0.9	1.3	1.2	1.1	1.0	1.1	0.8	0.9	0.9	0.7	0.4	0.8	1.1	0.9	0.9	1.0
Illnesses of mother	0.6	0.7	2.3	-0.8	-0.5	-0.8	1.5	-1.3	-0.6	-0.5	-1.3	-0.4	-0.7	-1.0	-1.0	0.0	-0.2	-1.1	-0.6	0.0	-0.6	-0.8	-0.7	-1.1	-0.9	-0.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.8	1.3	1.0	0.8	-1.1	0.7	0.9	0.8	0.8	0.5	0.6	0.9	0.5	0.7	1.0	0.9	0.9	0.8	0.9	0.9	0.8	1.0	0.8	0.9
Glaucoma (self-reported)	0.6	0.7	10.1	-0.2	0.3	-0.6	-3.2	-1.4	0.0	0.0	-1.0	0.1	-0.5	-0.3	-0.9	0.2	0.5	-0.7	-0.1	0.7	-0.5	-0.1	-0.2	-0.6	-0.5	-0.3
Leg fat percentage (right)	0.6	2.2	15.4	1.0	2.3	1.0	-3.9	1.2	1.4	1.3	0.8	2.1	1.5	1.4	1.2	1.4	0.9	0.9	1.0	0.8	0.9	0.9	1.4	0.8	1.0	1.0
Arm fat-free mass (right)	0.6	3.1	11.3	-1.6	-1.2	-1.4	3.4	-1.7	-1.4	-1.9	-2.4	-2.2	-1.5	-1.9	-1.8	-0.8	-1.0	-2.2	-1.8	-0.9	-1.3	-1.8	-1.6	-1.7	-1.7	-1.6
Exposure to tobacco smoke outside home	0.6	0.8	4.8	-0.6	-0.3	-0.5	-2.2	0.5	-0.8	-0.4	0.0	-0.2	-0.4	-0.5	-0.3	-0.9	-1.5	-0.4	-0.7	-2.0	-1.2	-0.9	-0.6	-0.6	-0.6	-0.8
Eye problems/disorders: None of the above	0.6	0.7	1.8	0.8	0.2	0.9	-1.0	1.4	0.9	0.5	1.0	0.8	0.9	0.9	1.1	0.1	0.5	0.9	0.6	0.3	0.7	0.8	0.9	0.9	0.9	0.8
Medication: Blood pressure	0.6	1.1	3.4	0.9	1.1	1.0	1.0	1.9	0.7	1.0	1.5	1.4	1.3	1.1	1.3	0.4	0.2	1.3	0.8	-0.1	0.7	0.7	1.0	1.0	1.0	0.9
Arm predicted mass (right)	0.6	2.8	10.4	-1.5	-1.2	-1.3	3.2	-1.7	-1.3	-2.0	-2.3	-2.1	-1.4	-1.8	-1.7	-0.9	-0.9	-2.1	-1.8	-0.7	-1.2	-1.6	-1.5	-1.6	-1.6	-1.5
Loneliness, isolation	0.6	0.8	9.2	0.6	0.9	0.8	-3.0	1.2	0.7	0.4	0.7	0.5	0.7	0.6	0.7	0.3	0.6	0.7	0.4	0.3	0.5	0.6	0.7	0.8	0.7	0.7
Commuting to job workplace: Walk	0.6	0.7	2.6	0.5	1.1	0.8	0.2	0.8	0.8	0.9	0.8	1.6	1.1	1.0	1.1	0.6	0.6	0.8	0.7	0.4	0.3	0.6	1.0	0.6	0.8	0.8
Mineral and other dietary supplements	0.6	0.7	1.2	0.8	0.9	0.8	-0.6	1.0	0.7	1.0	1.1	0.7	0.9	0.7	1.0	0.4	0.8	0.9	0.9	0.6	1.1	0.9	0.7	1.0	0.9	0.9
Leg fat percentage (left)	0.6	2.1	15.5	1.0	2.1	1.0	-3.9	1.2	1.3	1.3	0.8	2.0	1.4	1.4	1.2	1.3	0.9	0.9	1.0	0.9	0.7	1.0	1.3	0.8	1.0	1.0
Average weekly beer plus cider intake	0.6	0.9	2.8	0.8	0.8	0.9	0.5	1.7	1.3	0.4	1.5	1.2	1.1	1.0	1.4	-0.4	0.3	1.3	0.4	0.2	0.4	0.8	1.0	1.0	1.0	0.8
Basal cell carcinoma (self-reported)	0.6	0.7	9.2	-0.2	-1.0	-0.0	3.0	-1.1	-0.3	-0.5	-1.0	-1.2	-0.4	-0.4	-0.7	0.5	0.3	-0.8	-0.3	0.3	-0.0	-0.3	-0.3	-0.2	-0.3	-0.2
Arm predicted mass (left)	0.6	3.1	8.8	-1.6	-1.2	-1.4	3.0	-1.8	-1.4	-2.1	-2.4	-2.2	-1.5	-1.9	-1.8	-0.8	-1.0	-2.2	-1.9	-0.8	-1.2	-1.7	-1.5	-1.7	-1.7	-1.6
Crohns Disease (2017)	0.5	1.1	3.2	1.3	1.2	0.8	0.0	0.6	1.1	1.5	0.5	1.1	1.0	1.0	0.7	1.8	1.2	0.6	1.2	1.0	1.0	1.1	1.0	0.7	0.9	1.0
Mean Putamen Volume	0.5	0.6	5.2	-0.5	-1.0	-0.7	-2.3	-0.4	-0.7	-0.7	-0.3	-0.8	-0.6	-0.6	-0.5	-0.9	-0.8	-0.5	-0.8	-0.6	-0.0	-0.7	-0.7	-0.5	-0.6	-0.7
Neuroticism (2016)	0.5	0.7	7.2	0.7	0.7	0.7	-2.7	1.0	0.4	0.5	0.8	0.5	0.7	0.8	0.6	0.2	0.4	0.8	0.7	0.3	0.1	0.6	0.8	0.8	0.7	0.8
Blood Red Count	0.5	5.0	7.8	-2.6	-1.9	-2.6	-2.1	-2.0	-2.4	-2.0	-1.8	-1.7	-2.4	-2.3	-2.1	-2.7	-2.2	-2.0	-2.1	-2.0	-2.8	-2.1	-2.4	-2.3	-2.3	-2.3
Allergy or Eczema	0.5	1.3	2.9	-1.2	-0.9	-1.1	0.6	-1.5	-1.1	-0.6	-1.3	-1.1	-1.0	-1.4	-1.3	-0.2	-0.9	-1.3	-0.8	-0.8	-1.7	-1.2	-1.2	-1.3	-1.2	-1.2
Supplements: Zinc	0.5	0.6	4.4	-0.5	-0.0	-0.8	-2.1	-0.9	-0.2	-0.2	-0.9	0.1	-0.4	-0.6	-0.8	-0.0	-0.4	-0.8	-0.5	-0.3	-0.8	-0.7	-0.5	-1.0	-0.8	-0.7
Medication: Co-codamol	0.5	0.6	2.5	0.9	0.8	0.6	-1.6	1.2	0.3	0.6	1.1	0.9	0.7	0.9	0.8	0.1	0.2	0.9	0.5	0.1	0.6	0.6	0.7	0.7	0.7	0.6
Medication: Metformin	0.5	0.7	2.1	0.5	1.1	0.6	1.3	0.9	0.5	0.7	1.0	1.4	0.8	0.8	1.0	0.7	0.3	1.0	0.7	0.2	0.0	0.5	0.8	0.7	0.7	0.7
Current tobacco smoking	0.5	0.9	2.3	-0.9	-0.6	-1.1	-0.7	-0.5	-1.0	-0.5	-0.5	-0.6	-0.9	-0.8	-0.9	-1.1	-1.5	-0.8	-0.8	-1.5	-0.9	-1.0	-1.0	-1.0	-1.0	-1.1
Past tobacco smoking	0.5	1.0	4.0	-0.8	-0.9	-0.9	2.0	-0.8	-0.7	-1.4	-0.5	-1.0	-0.9	-1.0	-0.5	-1.8	-1.0	-0.6	-1.2	-0.7	-0.6	-0.9	-0.9	-0.7	-0.8	-0.9
Diabetes (self-reported)	0.5	0.8	1.9	0.8	1.2	0.8	1.1	1.1	0.7	0.7	1.2	1.4	1.0	1.0	1.0	0.7	0.5	1.2	0.8	0.4	-0.1	0.7	1.0	0.9	0.9	0.9
Depression (self-reported)	0.5	0.6	10.8	-0.2	-0.2	-0.4	-3.3	-0.0	-0.7	-0.3	-0.3	-0.2	-0.2	-0.3	-0.3	-0.4	-0.5	-0.2	-0.3	-0.4	-0.0	-0.5	-0.3	-0.3	-0.4	-0.4
Headache pain in last month	0.5	0.8	9.6	0.7	0.6	0.6	-3.1	0.7	0.8	0.2	0.7	0.7	0.6	0.8	0.7	-0.2	0.7	0.7	0.3	0.7	0.8	0.7	0.7	0.7	0.7	0.6
Birth weight	0.5	1.1	3.5	1.0	1.2	1.1	-1.9	0.6	1.2	0.2	0.5	0.8	1.1	1.0	0.9	0.8	1.5	0.7	0.6	1.6	1.0	1.1	1.2	1.0	1.0	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	6.6	-0.5	-0.1	-0.8	-2.6	-0.6	-0.7	-0.8	-0.8	-0.3	-0.6	-0.4	-0.8	-0.7	-0.5	-0.7	-0.7	-0.4	-0.8	-0.6	-0.5	-0.6	-0.8	-0.7
Medication: Omeprazole	0.5	0.6	3.1	-0.2	-0.8	-0.4	-1.5	1.2	-0.7	-0.2	1.0	-0.4	-0.6	-0.1	0.1	-1.8	-0.9	0.5	-0.2	-1.5	-0.5	-0.2	-0.5	0.3	-0.0	-0.3
Overall health rating	0.5	1.2	5.8	-1.0	-0.0	-1.0	-2.4	-0.3	-0.9	-0.9	-0.6	-0.4	-0.7	-0.7	-0.8	-1.2	-1.5	-0.8	-1.1	-1.6	-1.4	-1.3	-0.8	-1.0	-1.0	-1.1
Smoking status: Current	0.5	0.9	2.1	-0.9	-0.5	-1.1	-0.3	-0.6	-0.9	-0.3	-0.7	-0.6	-0.9	-0.8	-1.0	-0.8	-1.3	-0.9	-0.8	-1.4	-1.0	-1.0	-1.1	-1.1	-1.0	-1.1
Risk taking	0.5	0.7	1.2	0.7	1.0	0.8	-0.1	0.7	1.1	0.9	0.7	1.0	0.9	0.8	0.9	0.6	0.7	0.8	0.9	0.8	0.9	0.7	0.9	0.7	0.8	0.8
Pack years of smoking	0.5	0.8	5.1	-0.4	-0.9	-0.7	-2.3	-0.8	-0.6	-1.0	-0.9	-1.1	-0.8	-0.7	-0.9	-0.8	-0.5	-0.9	-0.9	-0.2	0.3	-0.7	-0.7	-0.6	-0.8	-0.7
Depression (Nagel 2018)	0.4	0.6	11.3	-0.1	0.2	0.1	-3.4	0.5	-0.1	-0.5	0.6	0.1	-0.1	0.2	0.4	-0.5	-0.1	0.5	-0.2	-0.3	-0.6	0.1	0.1	0.4	0.2	0.1
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	-0.6	-1.2	-0.4	1.1	-0.3	-0.5	-0.5	-0.3	-1.2	-0.8	-0.8	-0.5	-0.5	-0.8	-0.4	-0.5	-1.1	-0.2	-0.7	-0.8	-0.4	-0.5	-0.6
Irritable Bowel Disease (IBD)	0.4	0.9	1.8	-0.8	-0.2	-1.1	0.3	-1.2	-1.0	-0.3	-1.3	-0.6	-0.8	-1.1	-1.2	0.1	-0.9	-1.3	-0.7	-1.0	-0.9	-1.0	-1.1	-1.3	-1.1	-1.1
Major Depression (MDD)	0.4	0.5	4.7	-0.1	1.2	0.2	-2.2	0.4	0.5	0.7	0.5	1.3	0.6	0.5	0.6	0.4	0.4	0.4	0.5	0.3	-0.9	0.4	0.6	0.2	0.4	0.4
Blood White Count	0.4	2.9	4.5	-1.6	-1.9	-1.5	1.6	-1.6	-2.0	-2.1	-1.6	-2.1	-1.8	-1.9	-1.7	-1.4	-1.6	-1.6	-1.8	-1.3	-1.8	-1.6	-1.7	-1.6	-1.6	-1.6
Fluid intelligence score	0.4	0.7	5.5	0.3	0.5	0.7	2.3	-0.4	0.7	0.2	-0.5	0.2	0.6	0.1	0.2	1.4	1.5	-0.0	0.4	1.7	0.3	0.7	0.6	0.3	0.5	0.7
Illnesses of siblings	0.4	0.5	1.8	-0.5	-1.1	-0.7	0.9	-0.3	-0.7	-0.5	-0.1	-0.9	-0.9	-0.8	-0.6	-1.4	-0.7	-0.3	-0.6	-0.8	-0.3	-0.7	-0.8	-0.4	-0.6	-0.7
Asthma	0.4	0.8	8.0	-0.6	-0.4	-0.9	-2.8	0.0	-0.7	-0.7	0.1	-0.3	-0.8	-0.5	-0.5	-1.6	-1.0	-0.1	-0.7	-0.8	-0.8	-0.7	-0.6	-0.4	-0.6	-0.7
Breastfed as a baby	0.4	0.5	1.3	-0.7	-1.1	-0.6	1.0	-1.0	-0.7	-0.0	-0.8	-0.8	-0.7	-0.9	-0.8	0.2	0.0	-0.6	-0.1	-0.2	-1.0	-0.5	-0.7	-0.6	-0.6	-0.4
High blood pressure (siblings)	0.4	0.6	5.1	0.7	0.5	0.7	-2.2	0.8	0.4	1.1	0.6	0.5	0.7	0.7	0.6	0.8	0.5	0.6	0.9	0.2	0.4	0.6	0.6	0.7	0.6	0.6
Emphysema/chronic bronchitis	0.4	0.5	1.9	-0.4	-0.5	-0.5	0.2	-1.1	-0.2	-1.4	-1.0	-0.8	-0.7	-0.5	-0.8	-0.8	0.0	-0.8	-1.0	0.4	-0.4	-0.3	-0.4	-0.5	-0.5	-0.5
Medication: Ibuprofen	0.4	0.5	1.9	-0.9	-0.5	-0.5	-1.4	-0.6	-0.5	-0.8	-0.9	-0.7	-0.5	-0.7	-0.7	-0.0	-0.6	-0.8	-0.8	-0.5	-0.9	-0.8	-0.5	-0.7	-0.7	-0.6
Medication: Seretide 50 evohaler	0.4	0.5	1.1	0.8	0.7	0.7	-0.2	0.5	0.9	0.0	0.4	0.2	0.5	0.7	0.5	0.2	1.0	0.5	0.4	1.1	1.0	0.8	0.7	0.9	0.7	0.7
Whole body fat mass	0.4	1.7	6.1	-1.3	-0.1	-1.2	-2.5	-1.3	-1.0	-1.1	-1.6	-0.6	-1.0	-1.1	-1.2	-0.4	-1.2	-1.6	-1.3	-1.2	-1.6	-1.5	-1.0	-1.5	-1.4	-1.3
Had major operations	0.4	0.5	1.1	0.8	0.8	0.7	0.5	0.5	0.7	0.5	0.6	0.8	0.6	0.7	0.6	0.5	1.1	0.8	0.6	1.0	0.6	0.9	0.8	0.8	0.8	0.8
Leg pain on walking	0.4	0.5	9.4	0.0	-0.3	-0.1	-3.1	0.4	-0.1	0.0	0.4	-0.1	-0.1	-0.1	0.1	-0.6	-0.6	0.2	-0.1	-0.8	-0.4	-0.3	-0.1	0.0	-0.0	-0.1
Ever had bowel cancer screening	0.4	0.5	3.3	-0.6	-1.1	-0.6	-1.8	-0.2	-0.9	-0.1	-0.2	-0.6	-0.7	-0.5	-0.6	-0.6	-0.6	-0.4	-0.2	-0.9	-0.7	-0.6	-0.7	-0.4	-0.5	-0.6
Asthma (self-reported)	0.4	0.8	8.0	-0.7	-0.3	-0.9	-2.8	-0.0	-0.6	-0.6	-0.0	-0.2	-0.7	-0.5	-0.5	-1.5	-0.9	-0.2	-0.6	-0.8	-0.8	-0.7	-0.6	-0.5	-0.6	-0.7
Medication: Gliclazide	0.4	0.4	2.7	0.2	1.0	0.2	1.3	0.1	0.2	0.7	0.2	1.1	0.4	0.3	0.3	1.0	0.3	0.3	0.6	-0.1	-1.6	0.2	0.4	0.1	0.2	0.3
Financial situation satisfaction	0.4	0.4	6.6	0.6	0.0	0.5	-2.6	0.4	0.0	0.1	-0.1	-0.3	0.4	0.3	0.1	0.6	0.7	0.1	0.3	0.7	0.5	0.4	0.4	0.5	0.3	0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.5	-0.6	-0.8	-0.7	1.2	-0.7	-0.6	-0.9	-0.8	-0.8	-0.8	-0.6	-0.7	-0.5	-0.8	-0.7	-0.8	-0.5	-0.4	-0.8	-0.6	-0.7	-0.7	-0.6
High cholesterol (Self-reported)	0.4	0.8	2.1	1.0	0.9	0.9	-1.5	0.6	0.4	0.5	0.3	0.7	0.9	0.8	0.6	1.3	1.2	0.5	0.7	1.3	1.1	0.7	1.0	0.7	0.7	0.9
Medication: Paracetamol	0.4	0.7	4.1	0.5	0.1	0.5	-2.0	1.7	0.2	0.3	1.5	0.3	0.4	0.6	0.8	-0.9	-0.3	1.1	0.4	-0.7	0.0	0.4	0.3	0.9	0.7	0.5
Diastolic blood pressure, automated reading	0.4	1.2	2.8	0.9	1.7	0.8	-0.9	1.3	1.2	1.2	1.6	1.6	1.1	1.2	1.3	0.5	0.3	1.4	1.2	0.3	-0.4	1.1	1.1	1.0	1.1	1.0
Myopia	0.4	0.6	1.3	0.8	0.8	0.6	0.3	1.1	0.7	0.9	1.1	0.7	0.6	0.9	0.7	0.4	0.5	1.0	0.9	0.1	0.4	0.8	0.6	1.0	0.8	0.7
Bipolar Disorder (2018)	0.3	0.4	2.2	-0.6	-0.5	-0.5	-1.5	-1.1	-0.2	-0.5	-1.1	-0.2	-0.5	-0.6	-0.5	0.2	0.2	-0.9	-0.7	0.1	-0.5	-0.4	-0.4	-0.8	-0.6	-0.6
Waist Hip Ratio (WHR)	0.3	1.5	6.7	-1.2	-0.4	-1.5	-2.6	-1.3	-0.7	-1.7	-0.9	-0.3	-1.2	-0.7	-1.2	-1.6	-1.3	-1.0	-1.5	-0.4	-1.1	-1.0	-0.8	-1.3	-1.2	-1.1
Chronotype (morning person)	0.3	0.7	3.6	0.9	0.3	0.9	0.4	0.9	0.5	0.5	0.4	0.4	1.0	0.6	0.8	0.8	0.9	0.5	0.6	1.2	1.9	0.7	0.8	0.7	0.8	0.8
Tanning	0.3	3.1	11.4	-1.5	-2.1	-1.6	3.4	-0.9	-1.7	-1.8	-0.9	-1.5	-1.6	-1.5	-1.2	-2.6	-2.1	-1.2	-1.8	-2.1	-1.5	-1.7	-1.6	-1.4	-1.5	-1.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	4.8	-0.0	0.1	-0.4	-2.2	0.2	-0.2	-0.3	-0.0	0.3	-0.1	-0.0	-0.2	-0.6	-0.7	-0.2	-0.5	-0.7	0.1	-0.4	-0.2	-0.4	-0.4	-0.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.9	0.9	0.1	0.5	-1.4	0.3	0.0	0.6	0.3	-0.1	0.3	0.4	0.1	1.1	0.6	0.5	0.8	0.5	0.6	0.4	0.3	0.7	0.5	0.6
Vitamin and mineral supplements	0.3	0.4	0.8	0.7	0.9	0.5	0.9	0.7	0.8	0.2	0.6	0.8	0.7	0.7	0.7	0.2	0.4	0.6	0.2	0.6	0.9	0.6	0.7	0.5	0.6	0.5
Pack years adult smoking proportion	0.3	0.5	6.0	-0.2	-0.5	-0.4	-2.4	-0.5	-0.4	-0.7	-0.6	-0.8	-0.5	-0.4	-0.5	-0.5	-0.3	-0.5	-0.6	-0.0	0.4	-0.4	-0.4	-0.3	-0.5	-0.4
Trunk fat percentage	0.3	1.1	13.0	-0.7	0.6	-0.8	-3.6	-0.6	-0.4	-0.3	-0.8	0.4	-0.4	-0.4	-0.5	-0.0	-0.8	-0.8	-0.7	-1.0	-1.4	-0.9	-0.4	-1.0	-0.8	-0.8
Maternal smoking around birth	0.3	0.4	3.3	-0.3	-0.7	-0.3	-1.8	0.1	-0.7	0.1	-0.2	-0.8	-0.4	-0.4	-0.5	-0.2	-0.8	-0.3	-0.1	-1.1	-0.5	-0.5	-0.5	-0.3	-0.4	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	7.0	0.2	0.5	0.3	-2.7	0.6	0.1	0.1	0.6	0.3	0.3	0.3	0.5	0.1	0.1	0.5	0.2	-0.0	-0.1	0.3	0.3	0.5	0.4	0.3
Stomach or abdominal pain in last month	0.3	0.3	7.5	-0.1	0.1	-0.0	-2.7	0.1	-0.3	0.1	-0.3	-0.0	0.0	0.0	-0.2	0.2	-0.0	-0.3	-0.1	-0.2	0.1	-0.1	-0.1	-0.2	-0.1	-0.1
Sitting height	0.3	2.0	7.2	1.3	1.5	1.5	2.7	0.2	1.1	1.7	0.1	0.4	1.4	0.7	0.6	2.7	2.0	0.5	1.6	1.9	0.9	1.2	1.1	1.0	1.1	1.4
Body mass index (BMI)	0.3	1.4	2.3	-1.5	-0.2	-1.3	-1.1	-0.8	-1.0	-0.9	-1.2	-0.5	-0.9	-1.1	-1.0	-0.9	-1.4	-1.2	-1.2	-1.4	-1.5	-1.4	-1.1	-1.4	-1.3	-1.3
Number of incorrect matches in round	0.3	0.5	1.2	0.9	1.1	0.5	-0.3	0.4	0.7	0.6	0.6	1.0	0.6	0.9	0.6	0.4	0.6	0.7	0.7	0.7	0.3	0.7	0.8	0.6	0.6	0.6
Hair/balding pattern: Pattern 2	0.3	0.4	2.6	0.4	0.5	0.5	-1.4	-0.1	0.2	0.3	-0.6	-0.1	0.5	0.3	0.1	1.6	1.0	-0.2	0.4	1.0	1.0	0.3	0.4	0.3	0.2	0.5
Number of live births	0.3	0.4	0.8	-0.8	-0.4	-0.4	0.9	-0.3	-0.8	-0.8	-0.2	-0.5	-0.4	-0.4	-0.3	-0.7	-0.9	-0.4	-0.7	-0.9	-0.5	-0.7	-0.4	-0.5	-0.5	-0.5
Noisy workplace	0.3	0.3	1.3	-0.4	-0.5	-0.7	-0.3	-0.3	-0.4	0.3	-0.4	-0.3	-0.5	-0.4	-0.6	-0.6	-0.8	-0.5	-0.1	-1.1	-0.2	-0.7	-0.7	-0.6	-0.7	-0.7
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.3	-0.8	-1.2	-0.6	1.8	-1.3	-1.0	-0.6	-0.9	-1.3	-0.8	-0.9	-0.9	0.2	-0.1	-0.7	-0.4	0.2	-0.4	-0.4	-0.8	-0.6	-0.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.4	-0.8	-0.5	-0.4	-1.2	-0.4	-0.4	-0.6	-0.5	-0.7	-0.5	-0.6	-0.6	-0.0	-0.4	-0.5	-0.5	-0.5	-1.0	-0.6	-0.5	-0.4	-0.5	-0.4
Tense / ‘highly strung’	0.3	0.5	8.8	-0.0	0.9	-0.0	-3.0	0.3	0.2	0.1	0.4	1.0	0.3	0.4	0.3	-0.1	-0.0	0.4	0.1	-0.1	-0.7	0.0	0.4	0.1	0.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	3.7	-0.5	0.3	-0.6	-1.9	0.4	-0.2	-0.3	0.0	0.7	-0.0	-0.1	-0.0	-0.8	-1.1	-0.3	-0.7	-1.3	-0.8	-0.8	-0.2	-0.6	-0.5	-0.6
Medication: Paracetamol	0.3	0.5	3.0	0.1	-0.1	0.3	-1.7	1.4	0.2	0.3	1.3	0.2	0.2	0.3	0.6	-0.8	-0.2	0.9	0.4	-0.6	-0.3	0.3	0.2	0.7	0.5	0.3
Number of full brothers	0.3	0.4	0.6	-0.6	-0.7	-0.7	-0.6	-0.2	-0.2	-0.5	-0.4	-0.2	-0.5	-0.5	-0.4	-0.8	-0.8	-0.5	-0.7	-0.8	-0.7	-0.7	-0.5	-0.7	-0.7	-0.7
Wheeze or whistling in the chest in last year	0.3	0.6	6.1	-0.5	-0.2	-0.4	-2.5	0.7	-0.4	-0.4	0.7	-0.0	-0.4	-0.0	-0.0	-1.2	-1.1	0.2	-0.5	-1.4	-0.5	-0.4	-0.4	-0.1	-0.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.4	3.0	0.3	-0.2	0.4	-1.7	0.7	0.6	0.6	0.6	0.2	0.5	0.4	0.4	0.2	0.1	0.5	0.5	0.3	1.4	0.4	0.4	0.4	0.4	0.4
Medication for pain relief, constipation, heartburn	0.3	0.6	4.9	-0.1	-0.5	-0.5	2.2	-1.4	-0.3	-0.6	-1.0	-0.6	-0.5	-0.5	-0.7	-0.2	-0.0	-0.8	-0.5	0.5	0.3	-0.3	-0.4	-0.7	-0.5	-0.4
Chest pain or discomfort	0.3	0.4	2.0	-0.5	-0.2	-0.5	-0.1	-0.4	-0.6	-0.8	-0.2	-0.5	-0.8	-0.3	-0.5	-0.7	-0.8	-0.3	-0.7	-1.2	-1.4	-0.5	-0.5	-0.4	-0.4	-0.6
Diabetes diagnosed by doctor	0.3	0.5	2.5	0.5	1.1	0.5	1.6	0.5	0.5	0.6	0.6	1.0	0.6	0.6	0.6	1.0	0.4	0.7	0.7	0.4	-0.6	0.4	0.7	0.5	0.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.0	-0.8	-0.8	-1.0	0.6	-0.2	-0.9	-0.3	0.0	-0.2	-0.7	-0.7	-0.4	-1.4	-1.4	-0.2	-0.6	-1.1	-0.6	-0.9	-0.8	-0.8	-0.7	-0.8
Ever smoked	0.3	0.5	3.7	0.3	0.5	0.5	-1.9	1.0	0.3	1.1	0.7	0.6	0.5	0.6	0.4	0.9	0.1	0.6	0.9	-0.1	0.3	0.5	0.4	0.5	0.5	0.5
Irritability	0.3	0.6	5.5	0.3	1.1	0.4	-2.4	0.2	0.9	0.3	0.3	0.7	0.5	0.7	0.3	0.6	0.7	0.4	0.4	0.9	0.3	0.6	0.7	0.4	0.4	0.5
Leg fat mass (left)	0.3	1.0	4.8	-1.1	-0.0	-1.0	-2.2	-0.8	-0.7	-0.9	-1.2	-0.4	-0.7	-0.8	-0.9	-0.5	-0.9	-1.1	-1.1	-0.8	-1.1	-1.1	-0.8	-1.1	-1.1	-1.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.4	0.1	0.9	0.4	0.5	0.4	0.7	1.2	0.3	0.9	0.6	0.4	0.5	1.1	0.3	0.3	0.8	-0.1	-0.5	0.4	0.4	0.2	0.4	0.4
LDL Cholesterol	0.2	0.3	1.2	-0.0	-0.3	-0.4	-0.3	-1.1	-0.6	-0.8	-0.8	-0.5	-0.5	-0.3	-0.6	-0.0	0.4	-0.5	-0.4	0.7	0.3	-0.3	-0.2	-0.2	-0.4	-0.2
Schizophrenia (2014)	0.2	0.4	1.7	-0.6	-0.6	-0.6	-1.0	-0.0	0.1	-0.2	-0.3	-0.4	-0.7	-0.5	-0.6	-0.7	-0.8	-0.4	-0.4	-1.0	-1.3	-0.7	-0.6	-0.6	-0.6	-0.6
Ulcerative Colitis	0.2	0.2	0.9	-0.5	-0.4	-0.3	-1.0	-0.3	-0.7	-0.4	-0.5	-0.6	-0.4	-0.6	-0.4	-0.2	-0.5	-0.5	-0.4	-0.6	-0.5	-0.6	-0.5	-0.5	-0.4	-0.5
Blood Eosinophil Count	0.2	1.2	3.4	-0.8	-1.4	-1.0	-0.2	-1.0	-0.6	-1.8	-0.8	-1.6	-1.4	-1.1	-1.0	-1.8	-0.7	-1.0	-1.5	-0.5	-0.2	-0.7	-1.1	-0.8	-0.9	-1.0
Respiratory disease	0.2	0.4	4.7	-0.4	-0.2	-0.7	-2.2	-0.2	-0.5	-0.7	-0.1	0.0	-0.5	-0.2	-0.3	-1.0	-0.6	-0.2	-0.6	-0.3	-0.7	-0.5	-0.3	-0.4	-0.5	-0.4
Lung FEV1/FVC ratio	0.2	1.0	15.6	0.5	-0.7	0.6	4.0	-0.7	0.0	0.3	-0.6	-0.9	0.0	-0.2	0.1	1.4	0.9	-0.2	0.6	0.8	0.4	0.4	0.1	0.3	0.3	0.5
Relative age of first facial hair	0.2	0.4	1.4	-0.2	-0.4	-0.6	0.7	-1.0	-0.5	-0.7	-1.2	-0.4	-0.6	-0.6	-0.7	0.1	-0.1	-1.0	-0.7	-0.1	-0.8	-0.6	-0.5	-0.8	-0.7	-0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.2	2.5	0.3	0.5	0.0	-1.6	0.3	0.2	0.7	-0.0	0.8	0.2	0.4	0.2	0.6	0.1	0.0	0.3	-0.4	-0.4	-0.0	0.2	-0.0	0.0	0.1
Ever had hysterectomy (womb removed)	0.2	0.2	3.9	-0.3	-0.2	-0.1	-2.0	-0.1	-0.1	-0.2	-0.4	-0.0	-0.1	-0.1	-0.2	0.1	0.1	-0.3	-0.2	0.1	0.3	-0.2	-0.0	-0.3	-0.2	-0.1
Townsend deprivation index at recruitment	0.2	0.3	2.7	0.2	0.6	0.4	-1.6	0.4	0.7	0.2	0.1	0.7	0.5	0.6	0.4	0.2	0.6	0.3	0.2	0.4	0.2	0.3	0.5	0.4	0.3	0.4
Supplements: Glucosamine	0.2	0.3	0.8	0.7	0.2	0.7	-0.0	0.7	0.5	0.6	0.6	0.4	0.7	0.4	0.7	0.9	0.2	0.6	0.6	0.2	0.3	0.4	0.5	0.5	0.6	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	0.4	1.0	0.3	-1.0	0.2	0.4	-0.2	0.1	0.7	0.6	0.6	0.4	0.5	0.4	0.3	0.0	0.7	-0.1	0.3	0.7	0.3	0.3	0.4
Had menopause	0.2	0.3	4.5	-0.1	-0.4	-0.3	-2.1	-0.3	-0.3	-0.3	-0.4	-0.3	-0.4	-0.1	-0.3	-0.2	-0.0	-0.3	-0.3	0.0	0.1	-0.1	-0.2	-0.2	-0.2	-0.2
Impedance of arm (right)	0.2	1.0	17.8	-0.3	-0.5	-0.6	-4.2	-0.6	-0.8	-0.4	-0.1	-0.2	-0.7	-0.3	-0.5	-0.5	-0.8	-0.3	-0.4	-0.9	-0.8	-0.4	-0.5	-0.4	-0.4	-0.5
Happiness	0.2	0.2	2.2	0.3	0.4	0.4	-1.5	0.9	0.2	-0.2	0.5	0.4	0.5	0.4	0.5	-0.3	-0.0	0.5	-0.0	0.1	0.1	0.2	0.4	0.4	0.3	0.3
Medication: Lansoprazole	0.2	0.2	2.4	0.3	0.2	0.2	-1.5	0.5	-0.1	-0.2	0.4	0.1	0.1	0.4	0.2	-0.0	0.1	0.3	0.0	0.1	0.6	0.1	0.2	0.4	0.3	0.2
Impedance of arm (left)	0.2	0.7	15.1	0.1	-0.1	-0.1	-3.9	-0.2	-0.3	0.2	0.3	0.2	-0.2	0.1	-0.1	-0.1	-0.3	0.1	0.1	-0.5	-0.6	-0.0	-0.1	-0.0	-0.0	-0.1
Length of working week for main job	0.2	0.2	0.9	0.2	-0.4	0.3	-0.2	0.8	-0.0	-0.2	0.7	-0.4	0.3	0.1	0.3	-0.5	0.2	0.5	0.0	0.4	0.9	0.4	0.1	0.6	0.4	0.3
Exposure to tobacco smoke at home	0.2	0.3	1.5	-0.3	-0.3	-0.3	-1.2	-0.6	-0.4	0.2	-0.9	-0.4	-0.2	-0.5	-0.5	0.6	-0.2	-0.8	-0.1	-0.2	-0.2	-0.5	-0.4	-0.6	-0.5	-0.4
Peak expiratory flow (PEF)	0.2	0.5	1.0	0.7	0.3	0.8	-0.8	0.8	0.4	0.7	0.7	0.3	0.7	0.6	0.7	0.9	0.7	0.7	0.7	0.6	1.0	0.7	0.6	0.8	0.8	0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.9	-0.6	-0.8	-0.6	-0.1	-0.9	-0.4	-0.4	-0.7	-1.0	-0.8	-0.8	-0.7	-0.3	-0.4	-0.7	-0.5	-0.3	-0.2	-0.5	-0.8	-0.7	-0.6	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.2	2.1	0.1	-0.4	-0.3	-1.0	0.6	-0.1	-0.6	0.5	-0.5	-0.4	-0.1	-0.0	-1.4	-0.3	0.2	-0.4	-0.4	0.2	0.1	-0.3	0.2	-0.0	-0.2
Body fat percentage	0.2	0.8	14.4	-0.4	1.1	-0.3	-3.8	-0.2	0.1	0.2	-0.4	0.9	0.1	0.1	-0.1	0.4	-0.5	-0.4	-0.3	-0.6	-0.9	-0.5	0.0	-0.6	-0.4	-0.4
Worry too long after embarrassment	0.2	0.3	1.8	0.7	-0.1	0.6	-1.3	0.7	0.1	0.2	0.3	-0.2	0.5	0.2	0.4	0.4	0.6	0.4	0.4	0.6	0.9	0.3	0.4	0.6	0.5	0.5
Qualifications: College or University degree	0.2	0.6	2.3	-0.0	-0.9	-0.7	0.3	-1.5	-0.8	-0.6	-1.4	-0.8	-0.8	-0.8	-1.2	0.2	0.3	-1.1	-0.5	0.6	-0.0	-0.5	-0.6	-0.9	-0.8	-0.6
Leg fat mass (right)	0.2	0.8	4.8	-1.0	0.3	-0.8	-2.2	-0.7	-0.5	-0.7	-1.1	-0.1	-0.5	-0.6	-0.7	-0.3	-0.8	-1.0	-0.9	-0.8	-0.9	-1.0	-0.6	-1.0	-0.9	-0.9
Pulse rate, automated reading	0.2	0.7	2.6	0.8	1.1	0.6	-1.6	0.2	1.3	0.8	0.2	0.8	0.7	0.7	0.4	1.2	1.0	0.5	0.8	1.1	-0.1	0.8	0.7	0.5	0.6	0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	-0.7	-0.1	-0.3	-0.1	-0.6	-0.5	-0.1	-0.8	-0.5	-0.3	-0.6	-0.6	0.4	-0.4	-0.8	-0.3	-0.3	-0.0	-0.6	-0.5	-0.7	-0.5	-0.5
Average weekly red wine intake	0.2	0.2	1.1	-0.4	-0.4	-0.1	1.0	-1.0	-0.6	-0.2	-0.8	-0.4	-0.0	-0.5	-0.3	0.7	0.3	-0.5	-0.1	0.8	0.2	-0.2	-0.1	-0.4	-0.3	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	3.0	0.5	-0.3	0.3	-1.7	0.5	0.2	0.5	0.7	0.2	0.2	0.3	0.2	0.3	0.0	0.5	0.5	-0.1	0.0	0.3	0.2	0.4	0.4	0.3
Friendships satisfaction	0.2	0.3	1.2	-0.4	-0.1	-0.4	-1.1	-0.3	-0.4	-0.4	-0.6	-0.3	-0.3	-0.6	-0.6	-0.3	-0.4	-0.6	-0.5	-0.3	-0.9	-0.5	-0.4	-0.6	-0.5	-0.5
Breast cancer (self-reported)	0.2	0.3	0.9	-1.0	-0.3	-0.8	0.4	-0.4	-0.4	-0.3	-0.5	0.1	-0.4	-0.5	-0.4	-0.6	-0.5	-0.4	-0.4	-0.3	-0.6	-0.6	-0.5	-0.7	-0.7	-0.6
Wears glasses or contact lenses	0.2	0.2	0.6	0.7	0.8	0.2	-0.7	0.1	0.4	0.2	-0.3	0.6	0.5	0.5	0.2	0.5	0.3	-0.1	0.1	0.6	0.6	0.1	0.5	0.1	0.1	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.2	-0.5	-1.1	-0.7	-0.8	-0.7	-0.6	-0.2	-0.5	-1.0	-0.8	-0.8	-0.8	-0.6	-0.4	-0.5	-0.2	-0.3	-0.3	-0.5	-0.9	-0.5	-0.6	-0.5
Cholesterol lowering medication	0.2	0.3	4.9	0.2	0.2	0.1	-2.2	-0.1	-0.1	0.2	-0.3	0.2	0.1	0.2	-0.1	0.7	0.6	-0.1	0.3	0.6	0.3	0.3	0.2	0.1	0.1	0.2
Supplements: Calcium	0.2	0.2	1.6	-0.6	-0.2	-0.4	-1.3	-0.0	0.3	-0.2	0.0	0.3	-0.4	-0.1	-0.3	-0.4	-0.5	-0.2	-0.5	-0.7	-0.4	-0.3	-0.3	-0.4	-0.3	-0.5
Alcohol drinker status: Previous	0.2	0.2	0.8	0.2	0.9	0.3	-0.5	0.5	0.3	0.9	0.5	0.8	0.6	0.3	0.4	0.6	0.2	0.4	0.6	-0.0	-0.3	0.3	0.3	0.3	0.3	0.3
Schizophrenia vs Biploar Disorder	0.1	0.1	0.6	-0.3	-0.4	-0.3	-0.3	0.5	-0.1	0.1	0.3	-0.2	-0.2	-0.2	-0.2	-0.7	-0.5	0.1	-0.1	-0.7	-0.5	-0.3	-0.3	-0.1	-0.3	-0.3
Alzheimer’s Disease (in father)	0.1	0.1	1.6	0.3	0.3	-0.0	0.2	0.1	0.2	0.3	0.3	0.3	-0.1	0.1	0.2	-0.0	-0.1	0.2	0.2	-0.5	-1.3	0.1	0.1	0.1	0.1	0.0
HbA1C	0.1	0.1	0.7	-0.3	0.0	-0.3	0.4	-0.8	-0.3	-0.6	-0.5	-0.2	-0.3	-0.4	-0.4	-0.2	0.2	-0.4	-0.4	0.3	-0.7	-0.1	-0.1	-0.4	-0.3	-0.2
Smoking Status	0.1	0.3	2.7	-0.3	-0.1	-0.4	-1.6	-0.4	-0.4	-0.1	-0.7	-0.2	-0.5	-0.2	-0.7	0.0	-0.2	-0.7	-0.2	-0.3	-0.2	-0.3	-0.4	-0.5	-0.5	-0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.7	0.2	0.8	0.3	0.7	0.1	0.2	-0.0	0.3	0.7	0.4	0.4	0.3	0.3	0.2	0.3	0.1	0.1	-0.6	0.1	0.5	0.2	0.3	0.3
Diabetes (mother)	0.1	0.1	0.4	-0.1	0.0	-0.3	0.3	-0.2	-0.4	0.1	-0.4	-0.2	-0.2	-0.4	-0.3	0.0	-0.4	-0.4	-0.2	-0.6	-0.5	-0.5	-0.4	-0.5	-0.4	-0.3
Relative age voice broke	0.1	0.2	0.4	-0.6	-0.3	-0.2	0.1	-0.4	-0.4	-0.5	-0.6	-0.2	-0.3	-0.4	-0.3	-0.1	-0.1	-0.6	-0.6	-0.3	-0.6	-0.3	-0.3	-0.5	-0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.7	-0.3	-0.3	-0.3	-0.8	-0.1	-0.2	0.1	-0.6	-0.3	-0.2	-0.4	-0.3	0.2	-0.4	-0.5	-0.2	-0.4	-0.2	-0.5	-0.3	-0.5	-0.4	-0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	1.1	-0.2	-0.2	-0.2	0.8	0.1	0.2	-0.8	0.4	0.2	-0.0	0.1	0.2	-1.1	-0.4	0.2	-0.5	-0.2	-0.3	-0.1	0.1	0.1	-0.0	-0.1
Chronic bronchitis/emphysema (father)	0.1	0.2	1.2	0.3	-0.9	0.1	-0.3	0.1	0.0	-0.5	-0.1	-0.9	-0.2	-0.2	-0.1	-0.4	0.2	-0.1	-0.2	0.3	1.1	0.0	-0.1	0.2	0.0	0.0
High blood pressure (mother)	0.1	0.1	0.8	-0.4	0.1	-0.4	-0.3	0.2	-0.0	-0.2	0.5	0.3	-0.2	0.0	0.1	-0.8	-0.7	0.3	-0.1	-0.5	-0.9	-0.1	-0.2	-0.1	-0.1	-0.2
Qualifications: None of the above	0.1	0.2	2.6	0.4	0.3	0.2	-1.6	0.4	0.2	0.1	0.2	0.3	0.3	0.5	0.3	0.0	-0.1	0.1	-0.0	-0.3	0.6	0.1	0.3	0.2	0.2	0.1
Hair/balding pattern: Pattern 3	0.1	0.2	0.7	-0.3	-0.4	-0.5	0.8	-0.1	-0.3	-0.3	-0.0	-0.1	-0.3	-0.3	-0.3	-0.9	-0.8	-0.2	-0.4	-0.7	-0.6	-0.5	-0.4	-0.5	-0.4	-0.5
Pulse rate	0.1	0.1	0.9	0.1	-0.7	0.1	0.3	-0.3	0.0	-0.2	-0.3	-0.9	-0.1	-0.3	-0.4	0.3	0.3	-0.1	0.1	0.6	0.2	0.0	-0.1	0.2	-0.0	0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.7	-0.4	-0.2	-0.4	-0.8	-0.6	-0.3	-0.3	-0.6	-0.4	-0.5	-0.3	-0.5	-0.2	-0.2	-0.7	-0.5	-0.6	-0.5	-0.4	-0.5	-0.5	-0.5	-0.5
Prospective memory result	0.1	0.1	0.6	-0.1	0.0	-0.2	0.0	-0.7	-0.2	-0.3	-0.8	-0.1	-0.2	-0.2	-0.4	0.4	0.2	-0.6	-0.2	0.2	-0.2	-0.2	-0.1	-0.4	-0.3	-0.2
Lung cancer (father)	0.1	0.1	0.7	-0.2	-0.6	-0.1	0.8	0.2	-0.3	-0.2	0.2	-0.6	-0.3	-0.2	-0.2	-0.4	-0.5	-0.0	-0.2	-0.4	0.7	-0.2	-0.3	-0.1	-0.1	-0.2
Age at first live birth	0.1	0.1	0.4	0.0	-0.6	-0.1	-0.2	-0.2	-0.3	-0.5	-0.4	-0.6	-0.2	-0.3	-0.2	-0.3	-0.0	-0.4	-0.5	-0.1	0.5	-0.3	-0.2	-0.1	-0.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	1.1	0.3	0.3	0.5	0.1	-0.0	-0.1	0.5	-0.1	-0.0	0.4	0.2	0.1	1.1	0.6	-0.0	0.5	0.3	0.1	0.2	0.3	0.3	0.3	0.4
Number of full sisters	0.1	0.2	0.8	-0.2	-0.3	0.0	-0.8	0.5	-0.3	-0.8	0.3	-0.4	0.1	-0.1	0.1	-0.9	-0.6	-0.0	-0.6	-0.6	-0.1	-0.4	-0.1	0.0	-0.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	1.0	-0.1	0.4	0.2	-0.5	0.3	0.6	0.5	0.1	1.0	0.7	0.3	0.4	0.2	0.0	0.1	0.2	0.3	0.3	0.1	0.5	-0.1	0.1	0.1
Hypertension (Self-reported)	0.1	0.4	1.3	0.4	1.0	0.6	-0.5	0.9	0.5	0.2	0.8	1.1	0.8	0.8	0.9	0.3	0.1	0.6	0.2	-0.1	0.2	0.4	0.8	0.5	0.6	0.5
Illnesses of siblings: Diabetes	0.1	0.1	0.4	0.2	0.6	0.4	-0.4	0.4	0.2	-0.0	0.1	0.5	0.5	0.3	0.5	0.5	-0.0	0.2	0.1	0.1	-0.2	0.1	0.5	0.1	0.2	0.3
Long-standing illness, disability or infirmity	0.1	0.2	1.8	0.2	0.4	-0.2	-1.4	0.3	-0.5	-0.0	-0.0	0.3	0.0	-0.1	-0.1	-0.3	-0.6	-0.2	-0.3	-0.9	-0.5	-0.6	-0.1	-0.3	-0.3	-0.4
Number of self-reported non-cancer illnesses	0.1	0.2	4.2	0.1	0.4	0.1	-2.0	0.2	-0.2	0.1	-0.1	0.4	0.2	0.3	-0.1	0.3	0.1	-0.0	-0.0	0.2	0.4	0.1	0.3	-0.0	0.1	0.1
Medication: Bendroflumethiazide	0.1	0.2	0.9	-0.3	0.4	0.0	-0.4	1.0	0.2	0.3	0.9	0.5	0.2	0.2	0.5	-0.3	-0.7	0.5	0.1	-0.9	-0.1	-0.1	-0.0	0.2	0.2	0.0
Alcohol drinker status: Never	0.1	0.2	1.2	-0.4	0.1	-0.3	-1.1	-0.4	-0.0	0.0	-0.5	-0.2	-0.2	-0.3	-0.4	0.0	-0.3	-0.4	-0.2	-0.3	-0.6	-0.3	-0.3	-0.4	-0.4	-0.3
Pain experienced in last month	0.1	0.2	3.7	-0.0	-0.2	0.2	1.9	0.1	0.1	0.4	0.4	-0.1	-0.0	0.0	0.1	0.4	-0.2	0.3	0.5	-0.2	-0.4	0.1	-0.0	0.2	0.2	0.2
HDL Cholesterol	0.0	0.0	0.2	0.1	-0.2	-0.0	0.3	-0.4	0.1	-0.2	-0.3	-0.3	-0.1	-0.0	-0.2	0.1	0.3	-0.1	-0.0	0.4	0.4	-0.0	0.0	0.0	-0.1	0.0
Hair Pigment	0.0	1.1	2.1	1.2	0.8	1.1	-0.9	1.3	1.0	0.9	1.4	0.8	0.8	1.1	1.1	0.5	0.8	1.3	1.0	0.6	1.4	1.1	1.0	1.2	1.2	1.0
High blood pressure	0.0	0.1	0.3	-0.1	0.4	0.1	-0.0	0.4	-0.1	-0.3	0.2	0.4	0.2	0.2	0.2	-0.2	-0.4	0.0	-0.4	-0.5	-0.3	-0.1	0.2	-0.0	0.0	-0.1
Multivitamins +/- minerals	0.0	0.1	0.3	-0.2	-0.0	0.2	-0.6	0.1	0.2	0.4	0.1	0.1	0.2	0.1	0.1	0.4	0.1	0.1	0.4	-0.0	-0.4	0.1	0.1	0.1	0.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.7	-0.1	-0.5	0.1	0.8	-0.1	-0.2	-0.3	0.3	-0.3	-0.1	-0.1	-0.0	0.0	0.1	0.3	0.1	0.4	-0.1	0.1	0.0	0.2	0.2	0.2

Hub : Genes

MLH3

Models

Trait associations