TWAS hub - BCL2L15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.1087	0.0308	2.8e-05	0.018	0.041	0.016	0.044	0.026	2.0e-03	5.1e-06	2.8e-03	2e-06	2.2e-04
2	TCGA	Brain Lower Grade Glioma	0.0786	0.0307	1.2e-07	0.044	0.060	0.067	NA	0.064	8.1e-06	2.1e-07	4.9e-08	NA	9.2e-08
3	TCGA	Pheochromocytoma and Paraganglioma	0.0910	0.0580	8.0e-03	0.002	0.039	0.001	NA	0.007	2.7e-01	1.1e-02	2.8e-01	NA	1.6e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Hypothyroidism (self reported)	33.3	76.6	216.1	-3.6	1.0	14.7
Rheumatoid Arthritis	33.2	45.6	130.0	-2.6	-0.4	11.4
Hypothyroidism/myxoedema (self-reported)	26.1	51.0	146.4	-2.1	1.4	12.1
Medication: Levothyroxine sodium	18.9	32.0	88.0	-2.6	1.1	9.4
Taking other prescription medications	7.7	11.8	34.5	-0.7	0.8	5.9
Long-standing illness, disability or infirmity	6.5	10.0	29.1	-1.0	-0.1	5.4
Number of treatments/medications taken	4.9	8.9	26.1	-0.6	0.4	5.1
Alcohol drinker status: Never	4.2	5.0	7.6	-2.8	-1.9	2.0
Crohns Disease (2017)	3.9	8.6	19.4	-1.2	-2.2	-4.4
Medication: Bendroflumethiazide	3.8	5.8	11.0	2.3	3.3	0.9
Myopia	3.5	5.0	8.6	-2.1	-2.9	1.4
Diabetes (self-reported)	3.4	5.2	13.0	-1.3	0.9	3.6
Serious illness, injury or assault to yourself	3.3	4.0	9.1	-0.7	-1.6	3.0
Bipolar Disorder (2011)	3.2	3.1	8.8	0.6	0.5	3.0
Lupus	3.2	4.9	11.4	-1.0	1.5	3.4
Illnesses of siblings: Diabetes	3.0	3.7	6.7	1.1	2.6	1.8
Ever had prostate specific antigen (PSA) test	3.0	3.5	5.8	2.4	0.9	1.9
Breast Cancer	2.9	7.0	18.6	-1.1	-1.1	-4.3
Alcohol usually taken with meals	2.9	4.7	11.1	0.6	1.6	3.3
Medication: Cholesterol lowering	2.9	4.6	13.0	-0.6	0.5	3.6
Overall health rating	2.9	6.3	16.7	-1.4	-0.6	4.1
Wears glasses or contact lenses	2.8	3.3	7.2	-0.1	-2.7	1.6
Medication for cholesterol, blood pressure or diabetes	2.7	4.4	10.8	1.4	-0.7	-3.3
Number of full brothers	2.7	3.4	7.2	2.7	1.6	0.5
Illnesses of father: Heart disease	2.7	3.8	8.4	0.5	1.7	2.9
Body Mass Index (BMI) (2010)	2.6	3.5	5.3	-2.3	-2.2	-0.6
Crohns Disease (2012)	2.6	4.3	8.5	-1.3	-1.6	-2.9
Chest pain or discomfort	2.6	3.8	9.6	0.9	1.0	3.1
Diabetes diagnosed by doctor	2.6	4.2	8.9	-1.8	0.7	3.0
Blood clot in the leg (DVT)	2.3	2.9	4.8	2.2	1.8	0.9
Worry too long after embarrassment	2.3	3.9	11.1	0.5	0.7	-3.3
Number of self-reported non-cancer illnesses	2.3	3.9	8.2	-1.4	1.3	2.9
Heart attack/myocardial infarction (self-reported)	2.3	3.0	8.8	0.4	-0.3	3.0
Other serious medical condition/disability diagnosed by doctor	2.2	2.9	5.8	-0.7	-1.6	2.4
Heart attack	2.2	2.8	7.9	0.6	-0.1	2.8
Hayfever/allergic rhinitis (self-reported)	2.2	2.8	6.3	-1.4	0.6	-2.5
Mouth/teeth dental problems: Bleeding gums	2.2	2.9	7.4	0.1	1.1	2.7
Chronic bronchitis/emphysema (mother)	2.2	2.5	4.3	0.7	2.1	1.6
Alcohol intake frequency.	2.2	5.2	6.3	-2.0	-2.5	2.3
Commuting to job workplace: Car/motor vehicle	2.2	2.6	7.3	-0.2	0.5	-2.7
Birth weight	2.1	4.6	12.7	-0.8	0.6	-3.6
Commuting to job workplace: Walk	2.1	2.2	3.8	-1.6	-1.9	-0.6
Mouth/teeth dental problems: Mouth ulcers	2.1	3.4	5.2	-1.6	-2.3	-1.5
Deep venous thrombosis (DVT) (self-reported)	2.1	2.8	3.7	1.9	1.9	0.9
Medication: Metformin	2.0	2.8	7.4	-0.9	0.6	2.7
Severe depression (siblings)	2.0	2.3	5.1	-1.3	-2.3	0.0
Diabetes (mother)	1.9	2.4	4.2	-1.6	-0.7	-2.0
Health satisfaction	1.9	2.4	5.6	-2.4	-0.8	1.0
Medication: Seretide 50 evohaler	1.9	2.2	6.5	-0.0	2.5	0.1
Ever smoked	1.9	3.4	9.2	-0.9	0.2	-3.0
Length of working week for main job	1.8	2.0	5.2	-0.8	0.4	-2.3
Medication: Amlodipine	1.8	2.5	5.5	-2.4	-0.7	1.2
High blood pressure (siblings)	1.8	2.5	6.4	1.1	2.5	0.0
Commuting to job workplace: Cycle	1.8	2.1	3.0	-1.4	-1.2	-1.7
Reaction Time	1.7	3.3	9.5	0.4	0.2	-3.1
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	2.8	-1.7	-1.3	1.0
Hayfever, allergic rhinitis or eczema	1.7	3.8	7.8	0.9	1.6	-2.8
Mouth/teeth dental problems	1.7	2.7	3.8	2.0	1.7	-1.1
Illnesses of siblings	1.7	2.4	5.7	-1.2	-2.4	-0.2
Glaucoma (self-reported)	1.7	2.0	5.4	-2.3	-0.8	-0.1
Medication: Aspirin	1.7	2.2	5.1	0.6	1.1	2.2
Blood White Count	1.6	11.9	18.7	3.1	2.6	-4.3
Type 2 Diabetes (T2D) (2018)	1.6	3.0	5.3	-2.3	0.8	1.7
Ever had hysterectomy (womb removed)	1.6	1.8	3.4	-1.3	-0.5	-1.8
Age when periods started (menarche)	1.6	3.9	9.1	1.2	1.0	-3.0
Past tobacco smoking	1.6	2.9	7.5	1.0	-0.6	2.7
Allergy	1.6	3.8	5.8	-1.6	-2.4	1.7
Pulse wave Arterial Stiffness index	1.6	1.9	5.5	0.2	-0.0	-2.3
Shortness of breath walking on level ground	1.6	1.9	4.5	-0.5	-1.0	2.1
Angina (self-reported)	1.6	2.1	3.6	-1.9	-1.4	0.8
Mean time to correctly identify matches	1.6	3.0	7.1	1.3	0.5	-2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	2.2	-1.4	-1.5	1.2
Loneliness, isolation	1.6	2.1	4.7	-0.6	1.2	2.2
Ever had bowel cancer screening	1.6	1.8	2.1	1.4	1.5	1.2
Commuting to job workplace: Public transport	1.6	1.9	5.0	-0.6	-0.5	2.2
Risk taking	1.6	2.3	5.1	1.4	0.2	2.3
Irritable Bowel Disease (IBD)	1.5	3.5	5.9	-1.3	-1.8	-2.4
Angina	1.5	1.9	2.7	-1.7	-1.3	1.2
Tense / ‘highly strung’	1.5	2.5	4.4	0.7	2.1	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	2.3	-1.5	-1.5	-1.2
Allergy or Eczema	1.4	3.6	8.4	0.9	1.3	-2.9
Average weekly spirits intake	1.4	1.7	4.1	0.7	0.8	-2.0
Hearing difficulty/problems with background noise	1.4	2.3	4.5	-2.1	-0.7	-1.3
Hair/balding pattern: Pattern 3	1.4	2.0	3.3	0.3	-1.6	-1.8
Depression (self-reported)	1.4	1.7	4.2	-2.1	-0.1	0.9
Birth weight of first child	1.4	2.5	7.6	-0.2	-0.2	-2.8
Number of children fathered	1.4	1.6	3.1	-1.7	-0.8	-1.0
Medication: Aspirin	1.4	1.9	5.3	0.0	0.6	2.3
Bipolar Disorder (2018)	1.3	2.0	2.5	-1.4	-1.2	1.6
Schizophrenia (2018)	1.3	2.7	5.6	1.1	1.1	2.4
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	4.2	0.2	-0.2	2.0
Qualifications: CSEs or equivalent	1.3	1.7	4.3	-2.1	-0.9	-0.3
Number of incorrect matches in round	1.3	2.2	3.6	-0.1	-1.9	1.7
Pain all over the body in last month	1.3	1.4	2.3	-0.0	1.5	1.4
Pulse wave peak to peak time	1.3	1.5	4.0	-0.6	-0.4	2.0
Medication: Blood pressure	1.3	2.3	5.2	-1.0	0.9	2.3
Heart disease (mother)	1.3	1.6	4.5	-0.6	-0.2	2.1
Age at last live birth	1.3	1.9	3.2	1.8	1.6	-0.0
Irritability	1.3	2.2	3.8	0.1	2.0	1.7
Alzheimer’s Disease (in father)	1.2	1.3	3.1	0.3	-1.8	0.9
Supplements: Glucosamine	1.2	1.6	3.6	1.9	0.2	-1.1
Pulse rate, automated reading	1.2	3.8	4.9	1.9	2.2	1.7
Ever taken oral contraceptive pill	1.2	1.4	4.1	0.1	0.0	2.0
Alcohol drinker status: Previous	1.2	1.4	2.8	-0.2	-1.1	1.7
Ulcerative Colitis	1.1	1.6	3.0	-1.7	-1.4	0.1
Maternal smoking around birth	1.1	1.6	2.9	-0.2	-1.3	-1.7
Chronic bronchitis/emphysema (father)	1.1	1.3	2.3	-0.3	-1.2	-1.5
High blood pressure (mother)	1.1	1.5	3.3	-1.8	-0.2	1.0
Had menopause	1.1	1.4	3.8	1.9	0.3	0.4
Medication: Ramipril	1.1	1.4	2.4	-1.6	1.2	0.6
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.9	4.5	-1.0	0.0	2.1
Number of live births	1.1	1.5	2.5	0.9	1.0	-1.6
Headache pain in last month	1.1	1.9	4.1	-1.0	-0.7	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.2	3.1	-0.3	-1.8	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.3	1.2	1.5	-0.5
Leg pain on walking	1.1	1.4	1.8	-1.3	-1.3	0.8
Knee pain experienced in last month	1.1	1.6	2.6	-1.0	-1.6	1.1
Smoking status: Previous	1.1	1.7	4.4	-0.7	0.2	-2.1
Medication for cholesterol	1.1	1.7	3.5	-1.0	-0.8	-1.9
Mother’s age at death	1.1	1.4	1.8	1.0	1.1	-1.3
Bipolar Disorder or Schizophrenia	1.0	2.6	7.6	-0.0	0.1	2.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	3.2	-1.0	-0.7	1.8
Father’s age at death	1.0	1.3	2.3	1.2	0.4	-1.5
Lung cancer (father)	1.0	1.2	2.7	-0.7	-0.7	-1.6
Illnesses of mother	1.0	1.2	2.9	1.7	0.1	-0.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.4	-1.1	-0.4	-1.6
Mouth/teeth dental problems: Loose teeth	1.0	1.2	1.8	-1.0	1.4	0.9
Medication: Omeprazole	1.0	1.2	1.9	-1.1	-0.6	1.4
Comparative height size at age 10	1.0	5.5	8.4	-2.9	-2.8	-0.8
Pack years of smoking	1.0	1.4	3.1	1.0	0.6	1.8
Heel T-Score	0.9	7.0	14.1	3.8	1.1	2.4
BMI	0.9	5.3	7.5	-1.2	-2.7	2.7
Hand grip strength (left)	0.9	2.3	4.5	0.0	-1.5	-2.1
Hearing difficulty/problems: Yes	0.9	1.4	3.6	-1.9	-0.8	0.0
Ever used hormone-replacement therapy (HRT)	0.9	1.2	2.5	1.0	0.3	-1.6
High blood pressure	0.9	2.4	6.2	0.1	2.5	1.0
Medication: Atenolol	0.9	1.1	3.1	-0.2	-0.2	1.8
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.7	-1.1	-0.5	1.3
Mouth/teeth dental problems: Dentures	0.9	1.5	2.8	-1.7	-1.3	-0.4
Breastfed as a baby	0.9	1.2	3.1	1.7	0.2	-0.7
Pulse wave reflection index	0.9	1.1	3.2	-0.2	0.3	-1.8
Medication: Allopurinol	0.9	1.3	2.0	0.4	-1.4	-1.3
Hypertension (Self-reported)	0.9	2.4	6.2	-0.1	2.5	1.0
Mineral and other dietary supplements	0.9	1.2	3.5	-1.9	-0.3	-0.0
Medication: Atorvastatin	0.9	1.1	2.7	0.6	0.6	1.6
Alzheimer’s Disease (including proxy)	0.8	1.2	2.6	-0.9	-1.6	-0.1
Verbal and Numeric Reasoning (VNR)	0.8	1.9	3.6	-0.7	-1.2	-1.9
Triglycerides	0.8	1.3	1.9	-1.3	1.4	0.4
Waist Hip Ratio (WHR)	0.8	3.6	4.9	-2.2	-2.0	-1.4
Pack years adult smoking proportion	0.8	1.3	3.2	0.7	0.5	1.8
Average weekly fortified wine intake	0.8	1.0	2.8	-0.4	0.0	-1.7
Financial difficulties in last 2 years	0.8	1.1	2.9	-0.6	-1.7	-0.4
Eye problems/disorders: None of the above	0.8	0.9	2.1	-0.7	-1.5	-0.4
Neck or shoulder pain in last month	0.8	1.1	2.6	-1.6	-0.8	0.3
Number of full sisters	0.8	1.0	2.0	-0.9	-1.4	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	1.3	-1.0	0.4	-1.2
Illnesses of father: None of the above (group 1)	0.8	1.0	1.3	-1.1	-1.2	-0.6
Average weekly champagne plus white wine intake	0.8	1.1	2.7	-0.0	1.6	-0.7
Financial situation satisfaction	0.8	1.0	2.2	-1.5	-0.8	0.2
Average weekly beer plus cider intake	0.8	1.1	2.0	-0.6	-1.0	-1.4
Ovarian Cancer	0.7	0.9	2.2	0.6	1.5	0.1
Prostate Cancer	0.7	1.0	1.1	1.0	-1.1	-0.9
Fasting Glucose	0.7	0.9	1.6	0.3	0.9	-1.3
LDL Cholesterol	0.7	1.1	1.6	-1.3	-0.9	0.9
Blood Platelet Count	0.7	7.9	17.1	2.1	4.1	1.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.0	-0.5	1.4	0.9
Relative age of first facial hair	0.7	1.4	2.1	0.3	1.5	-1.4
Diabetes (father)	0.7	0.9	1.6	-1.1	-0.0	1.3
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.1	0.6	-0.2	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	2.6	1.6	1.4	0.8
Noisy workplace	0.7	0.8	2.0	-0.4	-1.4	0.5
Medication for pain relief, constipation, heartburn	0.7	1.2	3.4	-0.0	-0.3	-1.8
Eye problems/disorders: Cataract	0.7	0.8	2.0	1.4	0.6	0.2
Tinnitus: Yes, now most or all of the time	0.7	0.9	1.4	0.2	-1.1	-1.2
Leg fat percentage (left)	0.7	2.6	5.1	1.4	0.7	2.3
Unable to work because of sickness or disability	0.7	0.9	2.8	0.3	0.1	1.7
Depression (Nagel 2018)	0.6	0.9	2.6	0.1	0.3	1.6
Intelligence (Savage-Jansen 2018)	0.6	1.9	4.9	0.4	-0.7	-2.2
Schizophrenia vs Biploar Disorder	0.6	0.8	2.2	-1.5	-0.2	-0.3
Major Depression (MDD)	0.6	0.8	1.0	-0.7	-0.9	1.0
Coronary Artery Disease (CAD)	0.6	0.7	1.0	0.5	-0.9	1.0
Sensitivity / hurt feelings	0.6	1.1	3.0	-0.4	-0.3	-1.7
Impedance of leg (right)	0.6	2.9	4.1	1.4	2.0	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.3	1.8	0.8	0.1
Impedance of leg (left)	0.6	3.0	3.9	1.5	2.0	-1.6
Nervous feelings	0.6	1.1	2.2	-0.5	1.5	0.9
Forced vital capacity (FVC)	0.6	2.3	3.8	-1.6	-2.0	-0.7
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	3.8	-1.6	-1.9	-0.3
Medication: Paracetamol	0.6	1.0	3.1	-0.0	-0.2	1.8
Leg fat percentage (right)	0.6	2.2	4.4	1.3	0.8	2.1
Exposure to tobacco smoke outside home	0.6	0.8	1.9	-0.1	0.8	-1.4
Migraine (self-reported)	0.6	0.7	1.2	0.1	1.1	1.0
Qualifications: nursing, teaching	0.6	1.0	2.2	-0.8	-0.1	1.5
Breast cancer (self-reported)	0.6	0.8	1.2	-0.5	-1.1	-0.9
Medication: Gliclazide	0.6	0.7	1.5	-0.8	0.2	1.2
Miserableness	0.6	1.1	1.6	-1.3	1.0	0.8
Medication: Blood pressure	0.6	1.1	2.8	0.6	1.7	0.3
Ever depressed for a whole week	0.6	0.7	1.4	-1.2	-0.7	0.6
Vascular/heart problems diagnosed by doctor	0.6	1.6	2.7	0.0	-1.6	-1.5
Supplements: Calcium	0.6	0.7	1.3	0.7	-0.5	1.1
Basal cell carcinoma (self-reported)	0.6	0.7	1.7	0.4	0.6	-1.3
Smoking Status	0.5	1.1	3.0	0.2	0.6	-1.7
Cardiovascular Disease	0.5	1.8	4.5	-0.6	0.7	2.1
Chronotype (morning person)	0.5	1.2	3.5	-0.1	0.3	1.9
Medication for hormone replacement therapy	0.5	0.5	1.6	0.1	1.3	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	2.8	-1.7	-1.4	0.1
Exposure to tobacco smoke at home	0.5	0.6	0.8	0.9	-0.6	-0.8
Peak expiratory flow (PEF)	0.5	1.1	2.6	-0.4	-0.8	-1.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	0.4	1.2	0.2
Forced vital capacity (FVC), Best measure	0.5	1.9	3.3	-1.8	-1.5	-0.2
Body fat percentage	0.5	1.9	4.2	1.1	0.4	2.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.7	0.7	-0.8	-0.8
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.1	-0.0	-0.7	-1.1
Osteoporosis (self-reported)	0.5	0.6	1.4	1.2	0.5	-0.4
Illnesses of father: High blood pressure	0.5	0.6	1.1	-1.0	0.6	-0.5
Number of operations (self-reported)	0.5	0.7	1.4	-1.2	0.1	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.6	-0.1	-0.3	1.3
Impedance of whole body	0.5	2.3	3.0	1.3	1.7	-1.6
Depressed Affect (Nagel 2018)	0.4	0.8	2.0	-1.4	0.1	0.6
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.9	-0.9	-0.4	-0.6
Neuroticism	0.4	0.9	1.3	-1.2	-0.6	-1.0
Vitamin and mineral supplements	0.4	0.6	0.8	0.7	0.9	0.7
Trunk fat percentage	0.4	1.6	3.5	1.1	0.3	1.9
Townsend deprivation index at recruitment	0.4	0.6	1.1	1.0	0.8	-0.3
Stomach or abdominal pain in last month	0.4	0.4	1.0	-0.4	-1.0	0.4
Body mass index (BMI)	0.4	1.8	4.8	-0.1	-0.8	2.2
Time employed in main current job	0.4	0.5	1.0	-0.3	-0.7	-1.0
Asthma	0.4	0.8	1.7	0.7	1.3	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	0.9	-0.3	-1.0	-0.8
Hair/balding pattern: Pattern 4	0.4	1.1	2.9	-0.1	0.5	1.7
Suffer from ‘nerves’	0.4	0.7	1.7	-1.3	0.2	-0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.2	0.5	-0.4	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.1	-1.1	0.5	-1.0
Average weekly red wine intake	0.4	0.6	1.0	0.8	0.4	1.0
Friendships satisfaction	0.4	0.5	1.4	-0.3	-0.1	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.1	-0.4	0.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.6	-1.3	-0.2	1.0
Guilty feelings	0.4	0.7	1.4	-0.8	-1.2	0.1
Medication: Lisinopril	0.4	0.5	1.0	0.6	1.0	0.2
Cholesterol lowering medication	0.4	0.6	1.0	1.0	0.9	0.3
Worry (Nagel 2018)	0.3	0.7	2.0	-0.1	1.4	0.4
Age at First Birth	0.3	0.5	1.2	0.5	-0.2	1.1
HbA1C	0.3	0.3	0.8	-0.3	-0.2	0.9
Neuroticism (2016)	0.3	0.5	1.4	0.1	0.1	-1.2
Respiratory disease	0.3	0.8	0.9	-1.0	1.0	0.7
Supplements: Zinc	0.3	0.3	0.6	-0.5	0.7	-0.3
Current tobacco smoking	0.3	0.6	1.4	0.3	0.4	-1.2
Relative age voice broke	0.3	0.4	0.6	0.8	0.4	-0.7
Waist circumference	0.3	1.1	1.6	-0.4	-1.3	1.2
Fluid intelligence score	0.3	0.7	1.2	-0.6	-0.6	-1.1
Impedance of arm (right)	0.3	1.4	2.9	0.8	0.9	-1.7
Arm fat percentage (right)	0.3	1.1	2.9	0.1	-0.5	1.7
Impedance of arm (left)	0.3	1.2	1.6	0.7	1.2	-1.3
Loud music exposure frequency	0.3	0.3	0.6	-0.8	-0.0	0.5
Comparative body size at age 10	0.3	0.8	2.1	-0.6	-1.4	0.1
Age at first live birth	0.3	0.5	1.4	1.2	0.3	0.0
Emphysema/chronic bronchitis	0.3	0.4	0.9	-0.2	-0.4	1.0
Medication: Ibuprofen	0.3	0.4	0.9	-0.3	-0.3	0.9
Leg fat mass (right)	0.3	1.0	2.9	0.2	-0.0	1.7
Had major operations	0.3	0.4	0.9	0.1	0.3	1.0
Leg fat-free mass (right)	0.3	1.4	1.9	-1.4	-1.1	1.1
Arm fat percentage (left)	0.3	1.3	3.8	0.2	-0.1	2.0
Mood swings	0.3	0.5	0.8	-0.3	0.8	0.9
Smoking status: Current	0.3	0.5	1.0	0.4	0.6	-1.0
Leg predicted mass (right)	0.3	1.4	1.8	-1.3	-1.1	1.1
Eye problems/disorders: Glaucoma	0.3	0.3	0.5	-0.7	0.6	0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.6	-0.8	-0.7	-0.3
High cholesterol (Self-reported)	0.3	0.6	1.6	-0.3	0.3	1.2
Medication: Paracetamol	0.3	0.5	1.1	0.3	-0.4	1.1
Diastolic blood pressure, automated reading	0.3	1.1	2.0	1.4	0.4	-1.0
Leg fat mass (left)	0.3	1.0	3.0	0.2	-0.0	1.7
Ulcerative Colitis (UC)	0.2	0.4	0.9	-0.9	-0.3	0.3
Mean Putamen Volume	0.2	0.2	0.5	-0.7	-0.1	0.2
Lung FVC	0.2	1.2	3.0	-0.6	-0.6	1.7
Medication: Co-codamol	0.2	0.2	0.4	-0.2	-0.6	0.3
Leg fat-free mass (left)	0.2	1.0	1.5	-1.2	-0.8	0.9
Fed-up feelings	0.2	0.4	0.6	-0.7	0.7	0.0
Leg predicted mass (left)	0.2	1.1	1.5	-1.2	-0.8	1.0
Trunk fat mass	0.2	1.1	2.8	0.6	0.0	1.7
Qualifications: None of the above	0.2	0.4	0.6	-0.8	-0.3	-0.8
Neuroticism score	0.2	0.5	1.2	-1.1	0.4	0.1
Weight	0.2	0.9	1.7	-0.5	-0.8	1.3
Hip circumference	0.2	1.0	2.7	0.4	-0.3	1.6
Worrier / anxious feelings	0.2	0.4	0.7	0.8	0.7	0.1
Happiness	0.2	0.2	0.6	-0.8	0.0	0.0
Arm fat mass (right)	0.2	0.8	1.9	-0.2	-0.8	1.4
Standing height	0.2	1.6	4.0	-0.8	-0.1	-2.0
Gout (self-reported)	0.2	0.2	0.3	0.2	-0.5	-0.6
Wheeze or whistling in the chest in last year	0.2	0.3	0.6	0.4	0.4	-0.8
Whole body fat mass	0.2	1.0	2.7	0.5	0.1	1.6
Supplements: Vitamin C	0.2	0.3	0.3	0.6	-0.6	-0.4
Back pain experienced in last month	0.2	0.2	0.6	0.1	-0.3	0.8
Asthma (self-reported)	0.2	0.5	1.2	0.4	1.1	0.2
Arm fat mass (left)	0.2	0.9	2.3	-0.3	-0.5	1.5
Basal metabolic rate	0.2	1.0	1.8	-1.4	-0.9	0.5
Fractured/broken bones in last 5 years	0.2	0.2	0.4	-0.0	0.6	0.6
Age started oral contraceptive pill	0.2	0.3	0.3	0.6	0.4	0.5
Heart disease (siblings)	0.2	0.2	0.4	-0.4	-0.2	0.6
Neuroticism (Nagel 2018)	0.1	0.3	0.8	-0.9	0.4	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.3	-0.3	0.5
HDL Cholesterol	0.1	0.2	0.3	0.5	-0.1	0.6
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.3	0.1	-0.4
Schizophrenia (2014)	0.1	0.3	0.9	0.2	0.2	0.9
Blood Eosinophil Count	0.1	0.7	1.4	-0.8	0.5	-1.2
Blood Red Count	0.1	1.1	2.4	-1.6	-0.6	-0.6
Height	0.1	1.9	3.8	0.3	1.3	-1.9
Systolic Blood Pressure	0.1	0.4	0.9	-0.3	0.5	-1.0
Hair Pigment	0.1	3.0	8.2	-0.4	0.8	2.9
Tanning	0.1	1.2	3.2	0.1	-0.6	-1.8
Systolic blood pressure, automated reading	0.1	0.2	0.3	0.3	-0.5	-0.6
Hand grip strength (right)	0.1	0.3	0.7	-0.0	-0.8	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.6	-0.3	0.2
Multivitamins +/- minerals	0.1	0.2	0.4	-0.6	0.3	0.1
Sitting height	0.1	1.0	3.0	-1.7	-0.1	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.3	0.6	-0.1	-0.3
Had other major operations	0.1	0.1	0.2	-0.4	0.4	-0.1
Medication: Simvastatin	0.1	0.2	0.3	-0.5	0.1	0.5
Trunk fat-free mass	0.1	0.8	2.0	-1.4	-0.5	-0.3
Pulse rate	0.1	0.3	0.3	0.6	-0.5	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.2	0.3	0.4	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.3	-0.4	-0.2	0.5
Medication: Lansoprazole	0.1	0.1	0.2	-0.1	0.4	0.5
Trunk predicted mass	0.1	0.8	2.0	-1.4	-0.5	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.6	0.1	-0.7	-0.1
Arm fat-free mass (right)	0.1	0.4	0.8	-0.9	-0.2	0.4
Qualifications: College or University degree	0.1	0.3	0.5	-0.6	0.1	0.7
Arm predicted mass (right)	0.1	0.3	0.7	-0.8	-0.5	0.4
Family relationship satisfaction	0.1	0.1	0.4	-0.1	-0.2	-0.6
Whole body fat-free mass	0.1	0.7	1.7	-1.3	-0.6	0.3
Osteoarthritis (self-reported)	0.1	0.1	0.2	-0.5	0.0	0.1
Whole body water mass	0.1	0.8	1.9	-1.4	-0.7	0.4
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.4	0.6	-0.0	-0.4
Arm fat-free mass (left)	0.1	0.4	0.7	-0.8	-0.6	0.4
Arm predicted mass (left)	0.1	0.4	0.7	-0.8	-0.6	0.5
Lung FEV1/FVC ratio	0.0	0.2	0.3	-0.5	-0.2	0.5
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	0.1	-0.3	0.1
Alcohol intake versus 10 years previously	0.0	0.1	0.1	-0.3	-0.2	-0.2
Falls in the last year	0.0	0.0	0.0	0.2	-0.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.1	0.1	-0.3	-0.3	-0.1
Prospective memory result	0.0	0.0	0.1	0.0	-0.2	0.3
Hearing aid user	0.0	0.0	0.1	-0.1	-0.3	0.1
Pain experienced in last month	0.0	0.1	0.1	0.3	0.3	0.0

Hub : Genes

BCL2L15

Models

Trait associations