Hub : Traits :

Fed-up feelings

542 significantly associated models · 81 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 2 23453834 25141538 3 1 2.7e-09 2.2e-10 2.5e-02 88 UBXN2A
2 3 44204328 45606527 1 1 3.3e-07 2.0e-08 1.2e-04 53 TMEM42
3 3 48381826 51009435 18 1 5.1e-14 6.6e-13 1.9e-01 97 GPX1
4 3 135273949 137261517 3 1 9.5e-09 4.7e-10 1.3e-03 73 RP11-102M11.2
5 3 149722394 151134540 1 1 4.1e-12 1.1e-05 3.7e-01 96 RP11-103G8.2
6 7 116660803 118207833 1 1 7.6e-08 5.5e-10 4.0e-04 68 CTTNBP2
7 8 8092025 11891593 15 1 6.0e-13 4.3e-11 2.3e-01 97 FAM86B3P
8 9 119768572 121177842 1 1 2.3e-07 3.3e-07 1.0e+00 100 TLR4
9 11 46010847 48285906 8 1 1.4e-11 5.7e-10 2.5e-02 87 ZNF408
10 11 63316786 64820283 2 1 1.5e-08 7.9e-08 2.4e-03 68 PPP1R14B
11 12 111154626 112582540 1 1 1.5e-07 9.7e-07 2.4e-01 94 SH2B3
12 14 74424938 76226003 5 2 2.5e-10 3.1e-11 8.3e-02 93 AREL1 DLST
13 17 42774693 45796313 19 1 5.2e-12 2.4e-11 1.0e+00 100 KANSL1-AS1
14 18 49172179 51753106 1 1 1.5e-07 6.1e-12 2.3e-06 53 DCC
15 19 32209988 33668090 1 1 3.9e-10 1.0e-09 1.0e+00 100 DPY19L3
16 20 2429222 3827309 1 1 1.7e-07 5.2e-05 2.2e-01 91 FASTKD5

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Crohns Disease (2017) 2.85 2 1 3.0 0.00 1.0e+00 GPX1 PPP1R14B
Irritable Bowel Disease (IBD) 3.53 1 1 3.0 0.00 1.0e+00 GPX1
Ulcerative Colitis (UC) 2.60 1 1 3.0 0.00 1.0e+00 GPX1
Major Depression (MDD) 4.07 1 0 0.0 0.00 1.0e+00 GPX1
Reaction Time 3.27 1 1 3.0 0.00 1.0e+00 SH2B3
Verbal and Numeric Reasoning (VNR) 3.36 2 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1
Breast Cancer 2.02 2 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1
Ovarian Cancer 3.44 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Prostate Cancer 2.44 1 0 0.0 0.00 1.0e+00 GPX1
Age at First Birth 3.99 1 1 3.0 0.00 1.0e+00 GPX1
Coronary Artery Disease (CAD) 2.87 1 0 0.0 0.00 1.0e+00 SH2B3
Crohns Disease (2012) 2.53 1 1 3.0 0.00 1.0e+00 GPX1
HDL Cholesterol 1.76 1 0 0.0 0.00 1.0e+00 DPY19L3
LDL Cholesterol 1.94 1 0 0.0 0.00 1.0e+00 SH2B3
Lupus 2.20 1 0 0.0 0.00 1.0e+00 FAM86B3P
Neuroticism 8.30 6 2 6.1 -0.99 1.6e-04 AREL1 FAM86B3P KANSL1-AS1 RP11-102M11.2 TLR4 ZNF408
Primary Biliary Cirrhosis 3.51 3 1 3.0 0.00 1.0e+00 KANSL1-AS1 PPP1R14B SH2B3
Rheumatoid Arthritis 2.07 1 0 0.0 0.00 1.0e+00 SH2B3
Schizophrenia 2.61 2 0 0.0 0.00 1.0e+00 FAM86B3P RP11-102M11.2
Triglycerides 1.98 1 0 0.0 0.00 1.0e+00 ZNF408
Ulcerative Colitis 2.27 1 1 3.0 0.00 1.0e+00 GPX1
Blood Eosinophil Count 11.41 2 2 6.1 0.00 1.0e+00 KANSL1-AS1 SH2B3
Blood Platelet Count 2.82 7 6 18.2 0.77 4.4e-02 AREL1 DLST KANSL1-AS1 PPP1R14B RP11-102M11.2 SH2B3 UBXN2A
Blood Red Count 5.16 3 3 9.1 0.00 1.0e+00 KANSL1-AS1 SH2B3 UBXN2A
Blood White Count 7.13 7 5 15.2 0.53 2.2e-01 FASTKD5 GPX1 KANSL1-AS1 RP11-102M11.2 RP11-103G8.2 SH2B3 UBXN2A
Heel T-Score 3.35 5 3 9.1 0.21 7.3e-01 AREL1 DLST KANSL1-AS1 PPP1R14B ZNF408
BMI 2.06 5 2 6.1 -0.69 1.9e-01 DPY19L3 GPX1 PPP1R14B TLR4 TMEM42
Height 1.45 8 6 18.2 0.55 1.6e-01 AREL1 CTTNBP2 DCC GPX1 KANSL1-AS1 RP11-102M11.2 SH2B3 UBXN2A
Waist Hip Ratio (WHR) 3.11 5 3 9.1 0.19 7.6e-01 GPX1 KANSL1-AS1 PPP1R14B RP11-102M11.2 UBXN2A
Systolic Blood Pressure 5.50 6 5 15.2 0.68 1.4e-01 AREL1 GPX1 KANSL1-AS1 PPP1R14B SH2B3 ZNF408
Smoking Status 3.73 3 2 6.1 0.00 1.0e+00 CTTNBP2 GPX1 PPP1R14B
Allergy or Eczema 0.86 1 0 0.0 0.00 1.0e+00 SH2B3
Cardiovascular Disease 3.70 3 2 6.1 0.00 1.0e+00 PPP1R14B SH2B3 ZNF408
Hypothyroidism (self reported) 9.32 2 2 6.1 0.00 1.0e+00 PPP1R14B SH2B3
Type 2 Diabetes (T2D) 1.82 1 0 0.0 0.00 1.0e+00 SH2B3
Lung FEV1/FVC ratio 2.11 5 2 6.1 0.69 1.9e-01 AREL1 CTTNBP2 DLST GPX1 KANSL1-AS1
Lung FVC 4.13 6 3 9.1 0.65 1.6e-01 DCC GPX1 KANSL1-AS1 SH2B3 TMEM42 UBXN2A
Neuroticism 12.44 11 8 24.2 -0.97 9.3e-07 AREL1 CTTNBP2 DLST DPY19L3 FASTKD5 GPX1 KANSL1-AS1 RP11-102M11.2 TLR4 UBXN2A ZNF408
Chronotype (morning person) 1.65 1 0 0.0 0.00 1.0e+00 UBXN2A
Hair Pigment 0.20 2 1 3.0 0.00 1.0e+00 KANSL1-AS1 SH2B3
Tanning 0.38 2 0 0.0 0.00 1.0e+00 AREL1 SH2B3
Hand grip strength (left) 2.80 3 2 6.1 0.00 1.0e+00 AREL1 KANSL1-AS1 UBXN2A
Number of treatments/medications taken 5.62 4 4 12.1 0.60 4.0e-01 AREL1 DLST GPX1 SH2B3
Sensitivity / hurt feelings 6.03 2 1 3.0 0.00 1.0e+00 FAM86B3P KANSL1-AS1
Frequency of depressed mood in last 2 weeks 8.34 5 0 0.0 0.99 1.4e-03 FAM86B3P KANSL1-AS1 RP11-102M11.2 UBXN2A ZNF408
Relative age of first facial hair 3.85 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Systolic blood pressure, automated reading 5.11 6 4 12.1 -0.57 2.4e-01 AREL1 FAM86B3P GPX1 KANSL1-AS1 SH2B3 ZNF408
Vitamin and mineral supplements 1.88 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Medication: Co-codamol 2.59 1 0 0.0 0.00 1.0e+00 GPX1
Pack years adult smoking proportion 2.48 1 0 0.0 0.00 1.0e+00 GPX1
Impedance of leg (right) 2.64 5 3 9.1 -0.54 3.5e-01 AREL1 FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Leg fat-free mass (left) 1.96 4 2 6.1 0.24 7.6e-01 FAM86B3P GPX1 SH2B3 UBXN2A
Trunk fat percentage 2.45 4 4 12.1 0.56 4.4e-01 AREL1 DPY19L3 GPX1 KANSL1-AS1
Hand grip strength (right) 2.09 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Townsend deprivation index at recruitment 2.27 1 0 0.0 0.00 1.0e+00 CTTNBP2
Current tobacco smoking 3.21 2 0 0.0 0.00 1.0e+00 CTTNBP2 UBXN2A
Frequency of unenthusiasm / disinterest in last 2 weeks 7.70 5 0 0.0 0.98 4.1e-03 DCC GPX1 RP11-102M11.2 RP11-103G8.2 UBXN2A
Relative age voice broke 3.43 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Taking other prescription medications 6.11 5 3 9.1 0.58 3.1e-01 AREL1 DLST GPX1 PPP1R14B SH2B3
Age when periods started (menarche) 1.93 1 1 3.0 0.00 1.0e+00 GPX1
Heel bone mineral density (BMD) T-score, automated (left) 4.21 2 2 6.1 0.00 1.0e+00 FAM86B3P ZNF408
Qualifications: CSEs or equivalent 1.76 1 0 0.0 0.00 1.0e+00 GPX1
High blood pressure 4.34 3 3 9.1 0.00 1.0e+00 FAM86B3P SH2B3 ZNF408
Medication: Atenolol 2.93 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Levothyroxine sodium 8.25 3 2 6.1 0.00 1.0e+00 FAM86B3P PPP1R14B SH2B3
Sitting height 2.82 4 3 9.1 -0.65 3.5e-01 DCC KANSL1-AS1 UBXN2A ZNF408
Body mass index (BMI) 3.08 3 3 9.1 0.00 1.0e+00 DPY19L3 FAM86B3P GPX1
Impedance of leg (left) 2.74 5 5 15.2 -0.54 3.4e-01 AREL1 FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Leg predicted mass (left) 1.98 4 2 6.1 0.24 7.6e-01 FAM86B3P GPX1 SH2B3 UBXN2A
Trunk fat mass 2.13 4 2 6.1 0.49 5.1e-01 DPY19L3 FAM86B3P GPX1 KANSL1-AS1
Waist circumference 1.65 2 2 6.1 0.00 1.0e+00 DPY19L3 GPX1
Past tobacco smoking 3.47 2 0 0.0 0.00 1.0e+00 CTTNBP2 SH2B3
Alcohol usually taken with meals 2.60 1 1 3.0 0.00 1.0e+00 CTTNBP2
Nervous feelings 6.89 6 4 12.1 0.98 3.6e-04 AREL1 DLST FAM86B3P KANSL1-AS1 RP11-102M11.2 ZNF408
Frequency of tenseness / restlessness in last 2 weeks 7.75 4 3 9.1 0.98 2.2e-02 GPX1 KANSL1-AS1 RP11-102M11.2 ZNF408
Hearing difficulty/problems with background noise 2.73 2 0 0.0 0.00 1.0e+00 KANSL1-AS1 ZNF408
Hair/balding pattern: Pattern 2 1.92 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Forced vital capacity (FVC) 3.44 3 2 6.1 0.00 1.0e+00 GPX1 KANSL1-AS1 UBXN2A
Heel bone mineral density (BMD) T-score, automated (right) 4.71 3 2 6.1 0.00 1.0e+00 FAM86B3P KANSL1-AS1 ZNF408
Ever unenthusiastic/disinterested for a whole week 4.01 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Qualifications: None of the above 3.86 1 1 3.0 0.00 1.0e+00 GPX1
Heart attack 2.17 1 0 0.0 0.00 1.0e+00 SH2B3
Pain all over the body in last month 2.30 1 0 0.0 0.00 1.0e+00 GPX1
Fluid intelligence score 2.69 2 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1
Illnesses of siblings 2.17 1 0 0.0 0.00 1.0e+00 SH2B3
Neuroticism score 14.12 12 8 24.2 0.98 7.1e-08 AREL1 CTTNBP2 DCC DLST DPY19L3 FAM86B3P GPX1 KANSL1-AS1 RP11-102M11.2 TLR4 UBXN2A ZNF408
Weight 2.10 4 3 9.1 0.57 4.3e-01 DPY19L3 FAM86B3P GPX1 SH2B3
Impedance of arm (right) 3.47 4 3 9.1 -0.47 5.3e-01 FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Arm fat percentage (right) 2.26 3 2 6.1 0.00 1.0e+00 DPY19L3 FAM86B3P GPX1
Trunk fat-free mass 2.36 5 2 6.1 0.39 5.1e-01 AREL1 GPX1 SH2B3 UBXN2A ZNF408
Hip circumference 2.23 5 2 6.1 0.41 4.9e-01 DPY19L3 FAM86B3P GPX1 PPP1R14B SH2B3
Alcohol intake versus 10 years previously 2.74 1 0 0.0 0.00 1.0e+00 GPX1
Father's age at death 4.61 2 1 3.0 0.00 1.0e+00 GPX1 SH2B3
Worrier / anxious feelings 8.35 6 5 15.2 0.99 1.6e-04 AREL1 DLST FAM86B3P KANSL1-AS1 RP11-102M11.2 TLR4
Frequency of tiredness / lethargy in last 2 weeks 6.73 4 1 3.0 0.27 7.3e-01 DCC GPX1 UBXN2A ZNF408
Hair/balding pattern: Pattern 3 3.84 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Number of live births 1.92 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Forced expiratory volume in 1-second (FEV1) 4.42 4 2 6.1 0.14 8.6e-01 FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Qualifications: A levels/AS levels or equivalent 4.88 2 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1
Mouth/teeth dental problems: Dentures 1.92 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Ibuprofen (e.g. Nurofen) 2.93 2 0 0.0 0.00 1.0e+00 KANSL1-AS1 UBXN2A
Forced expiratory volume in 1-second (FEV1), Best measure 4.03 4 2 6.1 -0.35 6.5e-01 GPX1 KANSL1-AS1 UBXN2A ZNF408
Impedance of arm (left) 3.77 5 4 12.1 -0.38 5.3e-01 FAM86B3P GPX1 KANSL1-AS1 SH2B3 UBXN2A
Arm fat mass (right) 2.50 3 3 9.1 0.00 1.0e+00 DPY19L3 FAM86B3P GPX1
Trunk predicted mass 2.35 5 2 6.1 0.40 5.1e-01 AREL1 GPX1 SH2B3 UBXN2A ZNF408
Standing height 1.42 7 3 9.1 -0.28 5.5e-01 FAM86B3P GPX1 KANSL1-AS1 RP11-102M11.2 SH2B3 UBXN2A ZNF408
Exposure to tobacco smoke at home 2.38 1 0 0.0 0.00 1.0e+00 GPX1
Tense / 'highly strung' 5.02 3 1 3.0 0.00 1.0e+00 AREL1 FAM86B3P RP11-102M11.2
Seen doctor (GP) for nerves, anxiety, tension or depression 4.27 3 0 0.0 0.00 1.0e+00 AREL1 CTTNBP2 ZNF408
Hair/balding pattern: Pattern 4 6.30 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Birth weight of first child 2.45 1 1 3.0 0.00 1.0e+00 SH2B3
Peak expiratory flow (PEF) 2.88 2 1 3.0 0.00 1.0e+00 FAM86B3P KANSL1-AS1
Ever highly irritable/argumentative for 2 days 3.52 1 0 0.0 0.00 1.0e+00 GPX1
Qualifications: O levels/GCSEs or equivalent 2.29 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Paracetamol 4.81 3 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1 UBXN2A
Headache pain in last month 4.87 3 1 3.0 0.00 1.0e+00 KANSL1-AS1 RP11-102M11.2 TLR4
Medication for cholesterol, blood pressure or diabetes 2.37 1 1 3.0 0.00 1.0e+00 SH2B3
Gout (self-reported) 2.39 2 0 0.0 0.00 1.0e+00 PPP1R14B SH2B3
Hypothyroidism/myxoedema (self-reported) 8.76 3 2 6.1 0.00 1.0e+00 FAM86B3P PPP1R14B SH2B3
Birth weight 2.12 2 1 3.0 0.00 1.0e+00 SH2B3 UBXN2A
High blood pressure (siblings) 1.94 1 0 0.0 0.00 1.0e+00 SH2B3
Forced vital capacity (FVC), Best measure 3.46 4 2 6.1 -0.30 7.0e-01 GPX1 KANSL1-AS1 UBXN2A ZNF408
Body fat percentage 2.66 4 3 9.1 1.00 2.9e-04 AREL1 DPY19L3 GPX1 TMEM42
Leg fat percentage (right) 3.63 5 2 6.1 0.65 2.3e-01 AREL1 DPY19L3 FAM86B3P GPX1 TMEM42
Arm fat-free mass (right) 2.34 4 3 9.1 0.43 5.7e-01 FAM86B3P GPX1 SH2B3 UBXN2A
Exposure to tobacco smoke outside home 4.43 1 1 3.0 0.00 1.0e+00 CTTNBP2
Comparative body size at age 10 1.36 1 1 3.0 0.00 1.0e+00 FAM86B3P
Number of full brothers 2.75 1 0 0.0 0.00 1.0e+00 GPX1
Worry too long after embarrassment 4.78 3 1 3.0 0.00 1.0e+00 FAM86B3P KANSL1-AS1 RP11-102M11.2
Wheeze or whistling in the chest in last year 2.57 1 0 0.0 0.00 1.0e+00 GPX1
Age at first live birth 4.12 1 1 3.0 0.00 1.0e+00 GPX1
Health satisfaction 2.38 1 0 0.0 0.00 1.0e+00 GPX1
Qualifications: College or University degree 5.16 4 2 6.1 -0.92 8.1e-02 CTTNBP2 GPX1 KANSL1-AS1 PPP1R14B
Medication for pain relief, constipation, heartburn 4.73 4 1 3.0 -0.98 2.2e-02 AREL1 DLST GPX1 KANSL1-AS1
Neck or shoulder pain in last month 1.77 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 3.40 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Allopurinol 2.20 2 0 0.0 0.00 1.0e+00 PPP1R14B SH2B3
Mean time to correctly identify matches 3.50 2 1 3.0 0.00 1.0e+00 SH2B3 ZNF408
Whole body fat mass 2.44 4 2 6.1 0.59 4.1e-01 DPY19L3 FAM86B3P GPX1 TMEM42
Leg fat mass (right) 2.94 4 3 9.1 0.55 4.5e-01 DPY19L3 FAM86B3P GPX1 TMEM42
Arm predicted mass (right) 2.47 4 4 12.1 0.42 5.8e-01 FAM86B3P GPX1 SH2B3 UBXN2A
Alcohol intake frequency. 2.95 2 1 3.0 0.00 1.0e+00 DCC KANSL1-AS1
Comparative height size at age 10 1.92 5 2 6.1 -0.59 3.0e-01 DLST KANSL1-AS1 RP11-102M11.2 SH2B3 UBXN2A
Suffer from 'nerves' 5.39 4 2 6.1 1.00 7.8e-04 AREL1 DLST FAM86B3P ZNF408
Overall health rating 4.17 2 1 3.0 0.00 1.0e+00 GPX1 ZNF408
Age at last live birth 3.12 1 1 3.0 0.00 1.0e+00 GPX1
Leg pain on walking 3.02 2 0 0.0 0.00 1.0e+00 GPX1 KANSL1-AS1
Illness, injury, bereavement, stress in last 2 years 2.49 1 0 0.0 0.00 1.0e+00 CTTNBP2
Medication: Aspirin 2.70 1 0 0.0 0.00 1.0e+00 SH2B3
Hypertension (Self-reported) 4.15 3 3 9.1 0.00 1.0e+00 FAM86B3P SH2B3 ZNF408
Smoking status: Previous 3.23 1 0 0.0 0.00 1.0e+00 SH2B3
Whole body fat-free mass 2.24 5 3 9.1 0.34 5.8e-01 FAM86B3P GPX1 SH2B3 UBXN2A ZNF408
Leg fat-free mass (right) 1.97 4 2 6.1 0.24 7.6e-01 FAM86B3P GPX1 SH2B3 UBXN2A
Arm fat percentage (left) 2.27 3 2 6.1 0.00 1.0e+00 DPY19L3 FAM86B3P GPX1
Handedness (chirality/laterality): Left-handed 1.96 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Mood swings 12.77 11 5 15.2 0.98 4.8e-08 AREL1 CTTNBP2 DCC DLST DPY19L3 FAM86B3P GPX1 KANSL1-AS1 TLR4 TMEM42 ZNF408
Loneliness, isolation 7.51 4 0 0.0 1.00 9.0e-04 GPX1 KANSL1-AS1 SH2B3 ZNF408
Qualifications: nursing, teaching 3.60 1 0 0.0 0.00 1.0e+00 GPX1
Mouth/teeth dental problems: Mouth ulcers 3.24 2 1 3.0 0.00 1.0e+00 KANSL1-AS1 SH2B3
Medication for cholesterol 3.05 1 1 3.0 0.00 1.0e+00 SH2B3
Illnesses of father: None of the above (group 1) 1.81 1 0 0.0 0.00 1.0e+00 SH2B3
Smoking status: Current 3.00 2 0 0.0 0.00 1.0e+00 CTTNBP2 UBXN2A
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.84 1 1 3.0 0.00 1.0e+00 KANSL1-AS1
Whole body water mass 2.29 5 3 9.1 0.34 5.8e-01 FAM86B3P GPX1 SH2B3 UBXN2A ZNF408
Leg predicted mass (right) 1.98 5 2 6.1 0.20 7.5e-01 FAM86B3P GPX1 SH2B3 UBXN2A ZNF408
Arm fat mass (left) 2.39 3 3 9.1 0.00 1.0e+00 DPY19L3 FAM86B3P GPX1
Number of self-reported non-cancer illnesses 4.32 4 1 3.0 -0.99 8.6e-03 AREL1 PPP1R14B SH2B3 ZNF408
Average weekly champagne plus white wine intake 2.60 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Miserableness 11.16 9 5 15.2 0.99 6.6e-07 CTTNBP2 DPY19L3 FAM86B3P GPX1 KANSL1-AS1 RP11-102M11.2 RP11-103G8.2 UBXN2A ZNF408
Guilty feelings 9.71 6 4 12.1 0.93 6.7e-03 AREL1 DLST FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Financial situation satisfaction 3.32 1 1 3.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 4.04 3 1 3.0 0.00 1.0e+00 KANSL1-AS1 SH2B3 ZNF408
Medication: Bendroflumethiazide 2.71 2 0 0.0 0.00 1.0e+00 FAM86B3P SH2B3
Medication: Paracetamol 4.96 3 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1 UBXN2A
Medication: Lisinopril 2.39 1 0 0.0 0.00 1.0e+00 ZNF408
Illnesses of father: High blood pressure 1.74 1 0 0.0 0.00 1.0e+00 SH2B3
Ever smoked 3.78 2 1 3.0 0.00 1.0e+00 CTTNBP2 SH2B3
Basal metabolic rate 2.17 5 3 9.1 0.35 5.6e-01 DPY19L3 FAM86B3P GPX1 SH2B3 UBXN2A
Leg fat percentage (left) 3.60 5 2 6.1 0.64 2.4e-01 AREL1 DPY19L3 FAM86B3P GPX1 TMEM42
Arm fat-free mass (left) 2.55 5 3 9.1 0.42 4.8e-01 DPY19L3 FAM86B3P GPX1 SH2B3 UBXN2A
Average weekly beer plus cider intake 2.94 1 0 0.0 0.00 1.0e+00 FAM86B3P
Irritability 6.54 4 2 6.1 0.99 8.5e-03 AREL1 FAM86B3P KANSL1-AS1 TLR4
Fractured/broken bones in last 5 years 1.99 1 0 0.0 0.00 1.0e+00 KANSL1-AS1
Age started oral contraceptive pill 1.89 1 0 0.0 0.00 1.0e+00 GPX1
Diastolic blood pressure, automated reading 6.29 4 3 9.1 -0.70 3.0e-01 FAM86B3P GPX1 SH2B3 ZNF408
Vascular/heart problems diagnosed by doctor 4.27 3 2 6.1 0.00 1.0e+00 FAM86B3P SH2B3 ZNF408
Pain experienced in last month 4.03 3 1 3.0 0.00 1.0e+00 GPX1 KANSL1-AS1 SH2B3
Heart attack/myocardial infarction (self-reported) 2.24 1 0 0.0 0.00 1.0e+00 SH2B3
Pack years of smoking 2.03 1 0 0.0 0.00 1.0e+00 GPX1
Impedance of whole body 3.53 5 4 12.1 -0.55 3.4e-01 AREL1 FAM86B3P GPX1 KANSL1-AS1 UBXN2A
Leg fat mass (left) 2.93 4 3 9.1 0.54 4.6e-01 DPY19L3 FAM86B3P GPX1 TMEM42
Arm predicted mass (left) 2.47 4 3 9.1 0.46 5.4e-01 FAM86B3P GPX1 SH2B3 UBXN2A

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 13 0.3724 1.85
GTEx Adipose Visceral Omentum 11 0.5403 1.96
GTEx Adrenal Gland 9 0.6177 1.88
GTEx Artery Aorta 15 0.5039 1.93
GTEx Artery Coronary 11 0.9298 2.08
GTEx Artery Tibial 14 0.3722 1.86
GTEx Brain Caudate basal ganglia 7 0.7609 2.01
GTEx Brain Cerebellar Hemisphere 12 0.8059 1.92
GTEx Brain Cerebellum 12 0.6054 1.94
GTEx Brain Cortex 8 0.7729 1.99
GTEx Brain Frontal Cortex BA9 9 0.9740 2.07
GTEx Brain Hippocampus 4 0.7634 2.03
GTEx Brain Hypothalamus 6 1.0169 2.03
GTEx Brain Nucleus accumbens basal ganglia 7 0.8092 1.88
GTEx Brain Putamen basal ganglia 6 0.9615 1.96
GTEx Breast Mammary Tissue 10 0.5066 1.97
GTEx Breast Mammary Tissue (Male) 7 0.5868 1.83
GTEx Breast Mammary Tissue (Female) 9 0.5474 1.89
GTEx Cells EBV-transformed lymphocytes 11 0.7730 1.95
GTEx Cells Transformed fibroblasts 17 0.4049 1.85
GTEx Colon Sigmoid 12 0.8208 2.03
GTEx Colon Transverse 14 0.6783 1.90
GTEx Esophagus Gastroesophageal Junction 9 0.6228 1.96
GTEx Esophagus Mucosa 18 0.5422 1.88
GTEx Esophagus Muscularis 21 0.6498 1.95
GTEx Heart Atrial Appendage 11 0.6966 1.93
GTEx Heart Left Ventricle 9 0.5882 2.00
GTEx Liver 4 0.5579 1.78
GTEx Lung 17 0.5917 1.95
GTEx Muscle Skeletal 10 0.3460 1.88
GTEx Nerve Tibial 13 0.3009 1.86
GTEx Ovary 7 0.7709 2.08
GTEx Pancreas 9 0.5515 1.92
GTEx Pituitary 7 0.6278 1.93
GTEx Prostate 8 0.9581 2.19
GTEx Skin Not Sun Exposed Suprapubic 14 0.5693 2.09
GTEx Skin Sun Exposed Lower leg 16 0.4396 1.98
GTEx Small Intestine Terminal Ileum 5 1.0846 2.05
GTEx Spleen 10 0.7087 2.01
GTEx Stomach 11 0.7565 1.98
GTEx Testis 17 0.5388 1.93
GTEx Thyroid 15 0.3751 1.85
GTEx Uterus 8 1.4109 2.28
GTEx Vagina 7 1.1024 2.15
GTEx Whole Blood 6 0.3011 1.76
METSIM Adipose 6 0.1302 1.65
NTR Blood 7 0.2914 1.71
ROSMAP Brain Pre-frontal Cortex 16 0.3644 1.87
YFS Blood 4 0.0866 1.61
CommonMind Brain Pre-frontal Cortex 13 0.2419 1.74
TCGA Breast Tumor 2 0.2608 1.80
TCGA Breast Normal 3 0.0713 1.64
TCGA Ovarian Tumor 7 0.2396 1.77
TCGA Prostate Tumor 8 0.2313 1.69