TWAS hub - C2orf84

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.1230	0.0490	1.9e-09	0.073	0.080	0.078	NA	0.073	8.7e-07	2.6e-07	3.7e-07	NA	8.2e-07
2	TCGA	Breast Invasive Carcinoma	0.0718	0.0300	1.6e-11	0.029	0.062	0.055	NA	0.061	1.2e-06	1.0e-12	1.9e-11	NA	1.9e-12
3	TCGA	Colon Adenocarcinoma	0.0940	0.0430	2.2e-05	0.064	0.086	0.089	NA	0.086	1.4e-04	1.2e-05	8.0e-06	NA	1.1e-05
4	TCGA	Esophageal Carcinoma	0.1310	0.0590	4.2e-04	0.038	0.062	0.045	NA	0.063	2.3e-02	4.9e-03	1.5e-02	NA	4.8e-03
5	TCGA	Glioblastoma Multiforme	0.1340	0.0800	9.7e-03	0.067	0.046	-0.004	NA	-0.002	4.4e-03	1.6e-02	4.3e-01	NA	3.7e-01
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.1588	0.0543	5.0e-16	0.129	0.130	0.145	NA	0.132	2.8e-14	1.9e-14	5.8e-16	NA	1.2e-14
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.4267	0.1229	0.0e+00	0.177	0.153	0.198	NA	0.202	1.6e-19	6.8e-17	8.0e-22	NA	2.5e-22
8	TCGA	Brain Lower Grade Glioma	0.1842	0.0655	5.5e-11	0.098	0.093	0.097	NA	0.107	3.1e-11	1.1e-10	4.4e-11	NA	3.5e-12
9	TCGA	Liver Hepatocellular Carcinoma	0.1590	0.0710	2.7e-07	0.161	0.129	0.128	NA	0.123	5.2e-08	1.2e-06	1.4e-06	NA	2.1e-06
10	TCGA	Lung Adenocarcinoma	0.0981	0.0348	3.9e-16	0.144	0.142	0.145	NA	0.148	1.5e-16	2.8e-16	1.2e-16	NA	6.2e-17
11	TCGA	Lung Squamous Cell Carcinoma	0.1233	0.0424	1.3e-15	0.147	0.144	0.147	NA	0.144	2.4e-16	4.6e-16	2.1e-16	NA	4.7e-16
12	TCGA	Ovarian Serous Cystadenocarcinoma	0.0840	0.0490	7.7e-03	-0.003	0.027	0.001	NA	0.000	5.7e-01	5.8e-03	2.7e-01	NA	3.1e-01
13	TCGA	Pancreatic Adenocarcinoma	0.3380	0.0970	3.6e-13	0.220	0.292	0.346	NA	0.324	1.2e-09	9.9e-13	2.9e-15	NA	3.2e-14
14	TCGA	Prostate Adenocarcinoma	0.2184	0.0717	0.0e+00	0.210	0.200	0.229	NA	0.237	1.5e-21	1.5e-20	1.1e-23	NA	1.4e-24
15	TCGA	Stomach Adenocarcinoma	0.1410	0.0520	3.7e-10	0.142	0.148	0.140	NA	0.140	1.8e-10	7.7e-11	2.4e-10	NA	2.6e-10
16	TCGA	Testicular Germ Cell Tumors	0.3970	0.1110	1.3e-07	0.108	0.138	0.131	NA	0.137	1.2e-04	1.4e-05	2.3e-05	NA	1.5e-05
17	TCGA	Thyroid Carcinoma	0.1470	0.0550	2.8e-11	0.062	0.127	0.118	NA	0.108	1.2e-06	2.3e-12	1.4e-11	NA	1.2e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Reaction Time	9.6	18.3	26.2	-3.8	-3.0	-5.1	-4.8	-3.6	-4.4	-4.3	-4.0	-5.1	-5.1	-4.9	-1.3	-4.6	-4.9	-4.7	-4.2	-3.0
Medication: Seretide 50 evohaler	9.5	10.9	15.5	-2.6	-2.0	-3.7	-3.6	-3.0	-3.9	-3.8	-3.5	-3.7	-3.6	-3.8	-1.3	-3.8	-3.6	-3.4	-3.2	-2.3
Mean time to correctly identify matches	7.5	14.2	24.2	-3.8	-3.1	-4.9	-4.1	-2.4	-3.5	-3.4	-2.8	-4.6	-4.5	-4.4	-1.3	-4.1	-4.3	-4.3	-3.8	-2.8
Eye problems/disorders: Diabetes related eye disease	6.8	7.4	9.9	-3.0	-2.9	-3.1	-2.4	-0.8	-2.9	-2.6	-2.3	-3.0	-3.0	-2.8	-2.1	-3.1	-3.0	-3.1	-2.8	-2.7
Blood White Count	5.6	41.6	104.0	1.8	-0.0	5.7	10.2	10.2	6.0	6.4	6.6	7.0	8.7	7.6	-1.3	6.8	7.0	7.2	3.5	0.5
Serious illness, injury or assault to yourself	5.3	6.5	8.9	-2.9	-2.7	-2.6	-2.1	-0.7	-3.0	-2.8	-2.4	-2.8	-2.5	-2.6	-2.0	-2.6	-2.8	-2.9	-2.5	-2.4
Fed-up feelings	5.1	9.2	37.9	-0.6	-1.4	2.4	5.5	6.2	2.0	2.6	3.7	2.5	3.6	3.0	-2.4	3.0	2.6	2.2	0.4	-1.0
Eye problems/disorders: None of the above	5.1	5.9	9.4	2.6	2.7	2.3	1.9	-0.2	2.3	2.3	2.0	2.5	2.5	2.4	2.8	2.9	2.4	2.7	2.5	3.1
Sitting height	4.3	30.4	67.7	-3.7	-1.1	-6.2	-6.6	-8.2	-6.1	-4.7	-4.7	-6.3	-7.0	-6.1	-0.0	-5.7	-6.0	-6.7	-5.1	-2.1
Qualifications: O levels/GCSEs or equivalent	3.8	6.1	9.6	-1.6	-1.2	-2.3	-2.5	-2.8	-3.0	-2.9	-3.1	-2.6	-2.9	-2.8	-0.8	-2.6	-2.7	-2.5	-2.3	-1.9
Emphysema/chronic bronchitis	3.7	4.1	6.7	-1.9	-1.6	-2.6	-2.1	-1.3	-2.4	-2.5	-2.1	-2.4	-2.0	-2.3	-0.9	-2.3	-2.2	-1.9	-1.7	-1.6
Qualifications: NVQ or HND or HNC or equivalent	3.7	4.5	7.4	2.2	2.1	2.1	1.5	0.4	1.9	1.8	1.2	2.4	2.5	2.4	2.2	2.3	2.3	2.7	2.2	2.5
Guilty feelings	3.7	5.6	16.4	0.3	-0.4	2.2	3.9	4.1	2.1	2.3	3.1	2.1	2.9	2.6	-1.3	2.6	2.3	2.0	1.5	-0.3
Alcohol drinker status: Previous	3.6	4.2	6.6	2.5	2.2	2.6	1.4	0.4	2.1	1.8	1.4	2.2	2.3	2.3	1.3	2.1	2.4	2.2	2.3	1.9
Depressed Affect (Nagel 2018)	3.5	7.3	27.8	-0.7	-1.4	2.2	5.3	5.2	1.4	2.3	2.8	2.1	3.1	2.6	-2.9	2.6	2.3	1.7	0.4	-1.6
Had major operations	3.5	4.1	6.8	-1.4	-0.8	-2.3	-2.6	-2.3	-2.3	-2.2	-2.3	-2.4	-2.3	-2.3	-0.1	-2.1	-2.2	-2.1	-1.7	-0.8
Diabetes diagnosed by doctor	3.4	5.5	10.8	-3.2	-3.3	-2.5	-1.1	2.0	-2.2	-1.9	-1.1	-2.1	-1.5	-1.9	-3.1	-2.6	-2.2	-2.5	-2.8	-2.5
Mean Putamen Volume	3.2	3.6	8.6	2.8	2.9	1.5	0.1	-1.9	1.8	1.6	0.7	1.6	1.3	1.4	2.7	1.3	1.8	2.0	2.4	2.2
Medication: Amlodipine	3.2	4.5	9.5	-3.0	-3.0	-2.3	-0.3	1.6	-2.0	-1.6	-1.2	-1.8	-1.6	-1.8	-2.5	-2.0	-2.0	-2.0	-3.1	-2.6
High cholesterol (Self-reported)	3.1	5.5	14.2	0.6	0.1	2.2	3.8	3.6	2.4	2.6	2.5	2.5	2.9	2.7	-0.4	2.6	2.5	2.5	1.2	0.1
Bilateral oophorectomy (both ovaries removed)	3.0	3.5	6.9	-2.5	-2.6	-2.1	-1.1	1.0	-1.4	-1.2	-0.6	-1.8	-1.6	-1.7	-2.5	-2.1	-1.8	-2.3	-1.7	-2.4
Miserableness	3.0	5.2	18.9	-0.4	-0.9	2.0	4.3	4.2	1.4	2.0	2.2	2.0	2.8	2.4	-2.2	2.2	2.1	1.6	0.6	-1.2
Hearing difficulty/problems: Yes	2.9	4.4	6.9	2.4	2.1	2.3	2.0	0.3	2.1	2.1	2.0	2.2	2.5	2.4	0.8	2.0	2.6	2.4	2.6	1.1
Medication: Gliclazide	2.9	3.3	5.7	-2.4	-2.3	-2.1	-1.1	0.3	-2.0	-1.7	-1.1	-1.9	-1.7	-1.8	-1.7	-1.9	-2.0	-1.9	-2.0	-1.9
Schizophrenia vs Biploar Disorder	2.7	3.5	6.1	2.2	2.0	2.2	1.0	0.2	2.1	2.0	1.2	2.1	1.7	1.9	1.8	2.0	1.9	1.8	1.9	2.5
Number of treatments/medications taken	2.7	4.9	13.7	-2.9	-3.1	-1.6	0.4	1.9	-2.0	-1.7	-0.9	-1.9	-1.4	-1.7	-3.4	-1.6	-1.7	-1.7	-2.8	-3.7
Medication: Lansoprazole	2.6	2.9	6.6	1.0	0.7	1.9	2.1	2.1	2.1	2.1	2.6	1.6	1.7	1.8	-0.5	1.8	1.9	1.2	1.6	0.3
Loud music exposure frequency	2.6	2.9	4.9	1.0	0.9	1.6	2.2	1.1	1.9	2.1	2.2	1.6	2.0	2.0	0.7	2.1	2.0	1.7	1.7	0.8
Height	2.5	47.7	80.3	-6.8	-4.1	-7.7	-5.5	-6.5	-8.0	-5.7	-4.9	-8.1	-8.4	-7.5	-4.0	-7.1	-7.5	-9.0	-7.9	-6.0
Neuroticism	2.5	6.0	18.6	-0.0	-0.6	2.1	4.3	4.2	2.1	2.5	3.0	2.2	3.0	2.6	-1.7	2.6	2.4	1.8	1.3	-0.7
Neuroticism score	2.5	5.2	15.7	0.1	-0.6	1.8	3.7	4.0	2.2	2.5	2.8	2.1	2.8	2.5	-1.4	2.3	2.3	1.7	1.5	-0.5
Medication: Cholesterol lowering	2.5	3.9	10.0	0.4	-0.0	1.9	3.2	3.1	1.8	2.3	2.0	2.1	2.5	2.5	-0.8	1.9	2.3	1.8	0.9	-0.2
Alcohol intake frequency.	2.5	5.9	11.2	2.1	1.3	3.0	2.4	3.1	2.3	1.8	1.2	3.1	3.4	2.9	0.9	2.4	2.7	3.1	1.9	2.1
Coronary Artery Disease (CAD)	2.4	2.8	5.8	1.7	1.6	1.6	1.5	0.6	1.7	1.3	1.2	1.8	1.8	1.7	1.9	2.1	1.8	2.4	1.4	1.8
Financial situation satisfaction	2.4	3.0	5.4	1.3	1.1	1.8	2.3	1.4	2.1	2.2	2.0	1.9	1.9	2.0	0.4	1.9	2.1	1.9	1.4	0.3
Qualifications: CSEs or equivalent	2.3	3.1	6.0	1.4	0.9	2.1	2.4	1.7	1.5	1.5	1.0	2.4	2.3	2.1	0.6	2.0	2.0	2.3	0.9	0.8
Breastfed as a baby	2.3	2.9	5.3	-2.0	-1.9	-2.3	-1.6	-0.4	-1.7	-1.8	-1.4	-2.0	-1.6	-1.7	-1.0	-2.0	-1.8	-1.5	-1.5	-1.7
Medication: Atenolol	2.2	2.8	10.8	-2.2	-2.5	-0.6	1.3	2.5	-0.9	-0.2	0.4	-0.6	-0.7	-0.6	-3.3	-0.7	-0.8	-1.5	-2.0	-2.8
Medication for pain relief, constipation, heartburn	2.2	3.8	17.1	2.4	2.8	0.2	-1.9	-3.5	0.9	0.4	-0.8	0.7	-0.2	0.1	4.1	0.5	0.2	1.0	1.5	3.5
Mood swings	2.2	4.0	13.1	-0.3	-0.7	1.6	3.6	3.6	1.4	2.0	2.2	1.8	2.6	2.2	-1.3	2.1	1.9	1.5	0.5	-0.4
Unable to work because of sickness or disability	2.2	2.9	10.7	-2.5	-2.8	-1.5	-0.3	3.3	-0.9	-1.0	-0.4	-1.1	-0.5	-0.9	-2.3	-1.3	-1.1	-1.2	-2.3	-1.7
Verbal and Numeric Reasoning (VNR)	2.1	5.0	9.2	-3.0	-2.8	-2.2	-0.8	0.7	-2.1	-1.7	-1.1	-2.2	-2.2	-2.0	-2.6	-2.1	-2.2	-2.6	-2.9	-3.0
Neuroticism (2016)	2.1	3.0	10.1	0.4	0.1	2.1	3.2	2.3	1.4	1.9	2.3	1.8	1.7	1.8	-0.3	2.5	1.4	1.1	0.8	0.7
Medication: Co-codamol	2.1	2.4	5.1	-1.7	-1.7	-1.4	-0.3	0.5	-1.7	-1.8	-1.2	-1.6	-1.4	-1.8	-1.7	-1.3	-1.6	-1.0	-2.0	-2.3
Diabetes (self-reported)	2.1	3.2	8.9	-2.5	-2.7	-1.5	-0.5	2.3	-1.3	-1.1	-0.5	-1.4	-0.9	-1.1	-3.0	-1.9	-1.3	-1.8	-1.9	-2.3
Leg fat percentage (right)	2.1	7.5	30.6	-0.1	-0.9	1.2	4.3	5.5	2.7	2.7	3.1	2.5	3.6	2.8	-0.6	2.5	2.6	3.3	0.8	-0.4
Ever taken oral contraceptive pill	2.1	2.4	4.7	-1.5	-1.5	-1.5	-1.2	-0.5	-1.8	-1.7	-1.8	-1.6	-1.7	-1.6	-0.9	-1.5	-1.7	-1.5	-2.2	-1.4
Alzheimer’s Disease (in father)	2.0	2.2	8.5	0.1	0.6	-1.5	-2.5	-2.9	-1.0	-1.4	-2.0	-1.1	-1.5	-1.4	1.8	-1.2	-1.4	-0.7	-0.2	0.9
Alzheimer’s Disease (including proxy)	2.0	2.8	11.3	-0.1	0.2	-1.4	-2.6	-3.4	-1.6	-1.8	-2.2	-1.6	-1.9	-1.8	0.6	-1.9	-1.6	-1.4	-0.1	-0.2
Prospective memory result	2.0	2.4	5.0	1.6	1.5	1.1	1.3	0.2	1.6	1.3	1.0	1.5	1.8	1.6	1.8	1.7	1.6	2.2	1.8	1.6
Taking other prescription medications	1.9	3.0	9.2	-2.5	-2.7	-1.5	-0.3	1.7	-1.4	-1.0	-0.3	-1.4	-0.8	-1.1	-3.0	-1.7	-1.2	-1.8	-1.5	-2.5
Hearing difficulty/problems with background noise	1.9	3.1	4.6	1.7	1.3	2.0	1.9	1.1	2.1	2.0	1.8	2.0	1.9	1.9	0.5	1.9	2.1	1.9	1.8	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	14.1	-2.1	-2.8	-0.2	1.9	3.8	-0.6	-0.5	0.3	-0.5	0.2	-0.2	-3.3	-0.1	-0.4	-0.4	-1.5	-2.8
Supplements: Vitamin C	1.9	2.2	4.1	-1.5	-1.5	-1.1	-1.1	-0.2	-1.7	-1.6	-1.8	-1.6	-1.8	-1.6	-1.1	-1.3	-1.7	-1.6	-2.0	-1.4
Medication: Blood pressure	1.9	3.7	9.6	-2.9	-3.1	-1.8	1.2	2.8	-1.4	-1.0	0.3	-1.4	-0.3	-0.8	-2.9	-1.0	-1.1	-0.9	-2.3	-3.0
Leg fat percentage (left)	1.9	6.9	28.5	-0.1	-0.8	1.0	4.0	5.3	2.7	2.6	3.1	2.4	3.5	2.7	-0.6	2.3	2.5	3.2	0.8	-0.4
Risk taking	1.9	2.8	4.5	-1.7	-1.3	-1.8	-1.2	-1.6	-2.1	-1.6	-1.6	-1.8	-1.9	-1.7	-1.1	-1.7	-1.8	-2.1	-1.4	-1.6
Supplements: Zinc	1.8	1.9	8.9	0.2	0.8	-1.1	-2.3	-3.0	-1.0	-1.3	-1.4	-1.5	-1.6	-1.4	1.6	-0.9	-1.2	-0.7	-0.3	0.7
Father’s age at death	1.8	2.4	6.3	-0.8	-0.4	-1.8	-2.5	-1.8	-1.4	-1.4	-1.1	-1.7	-1.9	-1.8	0.3	-1.8	-1.8	-1.9	-0.9	0.3
Qualifications: A levels/AS levels or equivalent	1.8	3.9	10.4	-1.1	-0.4	-2.1	-2.4	-3.2	-2.1	-1.9	-1.9	-2.4	-2.5	-2.2	-0.2	-2.1	-2.0	-2.1	-1.4	-1.2
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	7.3	0.4	0.0	1.6	2.7	2.1	1.1	1.4	1.9	1.3	1.9	1.6	-1.2	1.6	1.7	1.2	1.1	-0.6
Illnesses of mother	1.8	2.2	3.8	1.0	0.8	1.2	1.5	1.4	1.6	1.7	2.0	1.4	1.7	1.7	1.0	1.8	1.5	1.7	1.0	1.5
Comparative body size at age 10	1.8	5.0	9.4	1.5	0.9	1.8	1.9	2.5	2.9	2.9	3.1	2.6	2.8	2.6	0.1	1.6	2.7	2.1	2.4	1.1
Average weekly red wine intake	1.8	2.7	4.8	-1.3	-0.7	-2.1	-2.0	-2.2	-1.6	-1.2	-1.1	-2.0	-2.1	-1.8	-0.4	-2.1	-1.8	-2.2	-1.1	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	3.3	-1.1	-0.6	-1.8	-1.7	-1.3	-1.7	-1.5	-1.0	-1.8	-1.5	-1.6	-0.6	-1.8	-1.5	-1.6	-1.5	-0.8
Number of self-reported non-cancer illnesses	1.8	3.0	6.8	-2.4	-2.5	-1.9	-0.3	1.1	-1.4	-1.2	-0.5	-1.7	-1.4	-1.5	-2.4	-1.6	-1.6	-1.7	-1.9	-2.6
Ever had prostate specific antigen (PSA) test	1.8	2.1	4.8	-1.2	-0.9	-2.1	-2.2	-0.8	-1.2	-1.3	-1.3	-1.8	-1.5	-1.7	0.2	-1.7	-1.7	-1.4	-1.4	-0.2
Frequency of depressed mood in last 2 weeks	1.7	2.4	15.1	-0.9	-1.5	0.6	2.4	3.9	1.0	1.0	1.8	0.4	1.1	0.7	-2.2	1.0	0.8	0.7	-0.3	-1.6
Supplements: Glucosamine	1.7	2.3	4.2	-1.4	-1.2	-2.0	-2.0	-1.2	-1.1	-1.1	-0.7	-1.9	-2.0	-1.8	-0.3	-1.7	-1.7	-1.9	-1.4	-0.7
Fluid intelligence score	1.7	3.5	6.9	-2.6	-2.4	-2.3	-1.1	0.6	-1.4	-0.9	-0.4	-2.0	-1.9	-1.7	-2.0	-2.0	-1.8	-2.4	-2.0	-2.3
Medication: Ibuprofen	1.7	2.1	7.1	0.1	-0.2	1.3	2.7	2.2	1.1	1.4	2.1	1.1	1.6	1.4	-1.5	1.4	1.5	0.9	0.9	-1.0
Lupus	1.6	2.4	4.2	-2.0	-2.0	-1.6	-0.5	1.1	-1.5	-1.8	-0.9	-1.8	-1.4	-1.7	-1.2	-1.1	-1.7	-1.0	-1.9	-1.8
Number of full sisters	1.6	1.9	4.8	0.9	0.7	1.2	1.6	1.5	1.8	1.9	2.2	1.4	1.4	1.6	-0.0	1.2	1.6	1.2	1.0	0.4
Loneliness, isolation	1.6	2.2	9.4	-0.7	-0.9	1.1	3.1	2.9	0.5	1.2	1.4	1.3	1.8	1.6	-1.4	1.6	1.2	1.0	-0.2	-0.7
Medication for cholesterol	1.6	2.4	9.9	2.2	2.6	0.8	-1.3	-3.1	0.6	0.5	-0.6	0.8	0.0	0.4	2.5	0.3	0.6	0.5	1.7	2.3
Illnesses of father: None of the above (group 1)	1.6	2.0	4.6	0.5	0.3	1.6	1.9	2.1	1.3	1.5	2.1	1.2	1.8	1.6	-0.6	1.6	1.6	1.0	0.8	0.3
Alzheimer’s Disease (in mother)	1.5	1.8	5.6	-0.4	0.0	-1.2	-2.1	-2.4	-1.4	-1.3	-1.5	-1.4	-1.4	-1.3	-0.4	-1.9	-1.0	-1.5	-0.3	-0.8
Blood Red Count	1.5	14.6	68.4	-0.7	-2.0	3.2	6.8	8.3	1.2	1.2	1.7	3.5	5.6	4.0	-2.5	3.7	3.2	4.5	0.1	-1.1
Hand grip strength (left)	1.5	4.0	7.3	2.6	2.7	2.1	1.1	-1.6	1.8	2.0	0.7	2.1	1.3	1.8	2.6	2.1	1.9	2.0	2.0	2.2
Angina	1.5	2.0	4.6	0.8	0.5	1.7	1.7	2.1	1.5	1.7	2.1	1.4	1.5	1.5	-0.8	1.2	1.6	0.8	0.9	0.2
Stomach or abdominal pain in last month	1.5	1.9	2.9	-1.7	-1.7	-1.7	-1.1	-0.3	-1.4	-1.3	-1.7	-1.3	-1.3	-1.3	-0.7	-1.5	-1.4	-1.1	-1.5	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	13.7	-1.5	-2.2	0.5	2.4	3.7	0.1	0.1	0.5	0.3	0.9	0.5	-2.5	0.7	0.3	0.3	-0.7	-2.1
Medication: Paracetamol	1.5	2.4	10.7	-2.0	-2.2	-0.6	1.1	2.3	-1.3	-0.9	-0.1	-0.8	0.3	-0.2	-3.3	-0.8	-0.4	-0.8	-1.3	-2.8
Worry too long after embarrassment	1.5	2.4	6.5	1.0	0.8	1.5	1.4	1.4	2.1	2.0	2.6	1.3	1.5	1.5	0.3	1.8	1.6	1.0	2.1	1.1
Shortness of breath walking on level ground	1.5	1.8	6.8	-1.7	-2.0	-0.8	0.1	2.6	-0.8	-0.9	0.1	-0.8	-0.3	-0.7	-2.4	-1.0	-0.7	-0.8	-1.3	-2.0
Breast Cancer	1.4	3.3	5.2	2.1	1.8	2.0	1.4	0.8	1.9	1.6	1.1	2.0	2.2	2.0	1.4	2.0	2.0	2.3	1.9	2.0
LDL Cholesterol	1.4	2.2	4.0	1.0	1.1	0.9	1.7	1.2	1.8	1.9	2.0	1.5	1.5	1.5	1.4	1.8	1.5	1.8	0.8	1.3
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.4	-1.1	-0.9	-1.1	-1.0	-0.5	-1.7	-1.7	-1.8	-1.3	-1.0	-1.4	-0.9	-1.4	-1.2	-0.9	-1.6	-1.3
Maternal smoking around birth	1.4	2.0	6.0	0.4	0.2	1.7	2.4	2.1	1.1	1.5	1.9	1.3	1.5	1.5	-0.9	1.6	1.4	0.9	0.6	-0.0
Financial difficulties in last 2 years	1.4	1.9	3.7	0.9	0.6	1.5	1.9	0.9	1.3	1.5	1.3	1.6	1.6	1.7	0.6	1.8	1.6	1.6	1.1	0.7
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	7.5	-1.8	-2.1	-0.2	0.8	1.9	-0.6	-0.1	0.3	-0.7	-0.6	-0.4	-2.7	-0.5	-0.5	-1.5	-1.4	-2.3
Angina (self-reported)	1.4	1.9	5.2	0.7	0.3	1.7	1.7	2.3	1.5	1.6	2.0	1.3	1.4	1.4	-0.9	1.2	1.5	0.8	0.7	0.2
Medication: Bendroflumethiazide	1.4	2.2	10.3	-1.1	-1.1	0.2	2.6	3.2	0.6	1.4	2.0	0.7	1.1	1.0	-2.0	0.7	0.8	0.3	-0.7	-1.4
Hand grip strength (right)	1.3	3.4	5.3	2.1	2.1	2.1	1.9	-0.9	1.8	2.3	1.3	2.2	1.5	2.0	1.7	2.1	2.0	1.7	1.7	1.6
Current tobacco smoking	1.3	2.1	5.0	1.3	1.0	1.4	1.5	0.9	1.2	1.1	1.1	1.5	2.2	1.8	0.4	1.4	1.8	1.9	1.8	0.9
Medication: Simvastatin	1.3	1.9	6.9	-2.1	-2.3	-0.7	1.2	2.6	-0.9	-0.6	0.1	-0.6	0.0	-0.3	-2.1	-0.4	-0.6	-0.5	-1.7	-1.9
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.9	0.8	0.8	1.6	2.0	0.8	1.2	1.6	1.9	1.4	1.3	1.5	0.2	1.8	1.4	1.0	0.8	0.6
Fractured/broken bones in last 5 years	1.3	1.7	6.4	-0.2	-0.6	1.2	2.0	2.5	1.3	1.5	1.9	1.0	1.0	1.1	-1.4	1.2	1.1	0.3	0.2	-0.8
Heart attack/myocardial infarction (self-reported)	1.3	1.7	2.8	-1.4	-1.3	-1.2	-1.1	-0.3	-1.7	-1.5	-1.5	-1.3	-1.1	-1.1	-1.2	-1.6	-1.3	-1.4	-1.1	-1.4
Neuroticism (Nagel 2018)	1.2	2.9	12.2	-0.9	-1.4	0.9	3.0	3.5	1.0	1.5	2.2	0.8	1.7	1.3	-2.2	1.4	1.2	0.4	0.2	-1.4
Relative age of first facial hair	1.2	2.4	5.5	1.7	1.3	1.5	1.2	0.5	1.5	1.2	0.7	1.8	2.0	1.8	1.4	1.6	1.7	2.3	1.6	1.5
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	7.0	0.1	0.3	-0.8	-2.2	-2.6	-1.4	-1.9	-1.8	-1.3	-1.7	-1.6	0.9	-1.1	-1.5	-1.1	-0.4	0.4
Friendships satisfaction	1.2	1.5	2.6	-0.9	-0.4	-1.3	-1.4	-1.5	-1.2	-1.0	-1.3	-1.3	-1.6	-1.4	0.0	-1.2	-1.4	-1.5	-1.5	-0.4
Eye problems/disorders: Glaucoma	1.2	1.4	3.9	-1.4	-1.5	-1.1	-0.0	0.7	-1.1	-0.9	-0.3	-1.1	-1.1	-1.0	-1.7	-1.2	-1.0	-1.0	-1.6	-2.0
Medication: Paracetamol	1.2	1.8	8.3	-1.5	-1.8	-0.1	1.4	1.9	-1.2	-1.0	-0.4	-0.5	0.3	-0.1	-2.9	-0.4	-0.2	-0.4	-1.1	-2.6
Number of operations (self-reported)	1.2	1.8	4.2	-1.6	-1.0	-2.0	-1.5	-0.8	-1.3	-0.9	-0.6	-1.7	-1.3	-1.4	-0.7	-1.6	-1.4	-1.7	-1.5	-0.9
Bipolar Disorder (2018)	1.1	1.7	3.6	-1.9	-1.8	-1.4	-0.4	0.8	-1.3	-1.0	-0.0	-1.5	-0.9	-1.1	-1.9	-1.3	-1.1	-1.5	-1.1	-1.8
Major Depression (MDD)	1.1	1.3	2.5	1.2	1.4	1.0	1.2	0.2	1.1	1.2	0.8	1.4	1.0	1.1	1.4	1.2	1.0	1.6	0.6	1.3
Medication for hormone replacement therapy	1.1	1.2	2.4	0.8	0.7	1.2	0.7	0.9	1.4	1.1	1.2	0.9	1.2	1.2	0.9	1.6	1.1	0.9	1.2	1.4
Severe depression (siblings)	1.1	1.3	3.2	-1.7	-1.8	-1.3	-0.6	1.6	-0.1	-0.2	0.1	-1.1	-1.0	-1.0	-1.1	-0.9	-1.0	-1.2	-1.2	-1.3
Impedance of leg (left)	1.1	5.2	16.6	0.9	-0.0	2.8	4.1	3.2	1.4	1.4	1.4	2.6	3.1	2.6	-0.5	3.0	2.3	2.9	1.1	0.1
Heart attack	1.1	1.4	2.5	-1.3	-1.2	-1.1	-1.1	-0.2	-1.5	-1.4	-1.4	-1.1	-0.9	-1.0	-1.2	-1.6	-1.1	-1.3	-0.9	-1.3
Body fat percentage	1.1	4.5	22.2	-0.5	-1.0	0.3	3.3	4.7	2.1	2.1	2.7	1.6	2.6	1.9	-0.7	1.6	1.8	2.4	0.1	-0.7
Suffer from ‘nerves’	1.1	1.8	10.7	-0.6	-1.3	0.2	1.7	3.3	1.5	1.4	2.0	0.8	1.2	1.0	-0.9	1.0	0.8	0.7	0.4	-0.5
Average weekly champagne plus white wine intake	1.1	1.5	6.5	0.0	0.7	-1.2	-2.2	-2.5	-0.7	-0.7	-0.3	-1.6	-1.6	-1.4	0.7	-1.2	-1.0	-1.3	-0.1	0.2
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.0	0.5	0.3	1.3	1.7	1.4	1.0	1.1	1.1	1.1	1.0	1.1	0.0	1.3	1.0	1.2	0.3	0.2
Mouth/teeth dental problems: Dentures	1.0	1.8	4.3	-2.1	-1.9	-1.3	0.2	1.8	-1.3	-0.9	0.3	-1.1	-0.4	-0.8	-1.9	-0.9	-1.0	-1.0	-1.8	-1.5
Glaucoma (self-reported)	1.0	1.2	3.3	-1.4	-1.5	-1.3	-0.1	0.7	-0.9	-0.8	-0.0	-1.3	-0.9	-1.0	-1.5	-1.1	-1.0	-1.0	-1.0	-1.8
Neck or shoulder pain in last month	1.0	1.5	4.3	0.1	-0.2	1.1	1.8	2.1	0.9	1.1	1.5	1.1	1.7	1.4	-1.3	0.9	1.4	0.8	1.0	-0.5
Medication: Allopurinol	1.0	1.3	3.4	-0.4	0.2	-1.3	-1.9	-1.7	-1.1	-1.0	-0.8	-1.4	-1.3	-1.2	0.0	-1.3	-1.1	-1.4	-0.7	-0.1
Commuting to job workplace: Walk	1.0	1.1	2.7	-1.1	-1.2	-1.0	-0.5	-0.1	-0.8	-0.7	-0.2	-1.3	-1.2	-1.1	-1.4	-1.1	-1.0	-1.3	-0.9	-1.6
Smoking status: Current	1.0	1.6	4.0	1.1	0.8	1.3	1.4	0.8	1.1	1.0	1.0	1.3	2.0	1.6	0.1	1.2	1.7	1.6	1.7	0.5
Illnesses of father: High blood pressure	1.0	1.3	3.4	-1.4	-1.5	-0.8	-0.2	0.7	-1.2	-0.9	-1.1	-0.6	-1.0	-1.0	-1.3	-1.0	-1.2	-1.2	-1.8	-1.0
Cholesterol lowering medication	1.0	1.5	2.9	-1.6	-1.7	-1.4	-0.3	0.8	-1.0	-1.0	-0.4	-1.4	-1.1	-1.2	-1.3	-1.0	-1.2	-1.0	-1.5	-1.6
Depression (Nagel 2018)	0.9	1.4	9.4	-0.5	-0.9	0.6	1.7	3.1	0.9	0.8	1.3	0.3	0.8	0.5	-1.7	0.7	0.6	0.5	-0.2	-1.2
Age at First Birth	0.9	1.4	5.8	0.1	-0.2	0.9	1.6	2.4	1.2	1.2	1.8	1.0	1.2	1.1	-0.3	1.2	1.0	0.9	0.4	0.3
Trunk fat percentage	0.9	3.5	19.5	-0.9	-1.2	-0.0	2.9	4.4	1.7	1.8	2.5	1.1	2.1	1.4	-0.9	1.3	1.3	1.9	-0.3	-0.9
Multivitamins +/- minerals	0.9	1.1	2.9	-0.8	-0.4	-1.7	-1.4	-1.3	-0.9	-0.8	-1.0	-1.2	-1.2	-1.2	0.7	-1.1	-1.2	-0.7	-1.1	-0.2
Nervous feelings	0.9	1.6	3.2	1.4	1.3	1.1	0.9	-0.2	1.4	1.2	1.1	1.2	1.3	1.2	1.3	1.3	1.3	1.4	1.8	1.3
Standing height	0.9	8.7	18.1	-2.6	-0.8	-3.2	-2.1	-4.3	-3.4	-1.8	-1.9	-3.4	-3.9	-3.1	-1.0	-2.7	-3.1	-4.0	-3.7	-2.1
Eye problems/disorders: Cataract	0.9	1.0	3.2	-1.1	-1.2	-0.7	-0.7	1.2	-0.4	-0.6	-0.1	-1.1	-0.7	-0.8	-1.8	-1.2	-0.6	-1.0	-0.8	-1.6
Supplements: Calcium	0.9	1.0	2.3	1.5	1.5	0.9	0.2	-1.2	0.8	0.9	-0.2	1.2	0.8	1.0	1.2	0.4	1.1	1.2	1.0	0.8
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.3	-2.3	-2.2	-1.4	-0.1	0.8	-1.4	-0.9	-0.1	-1.4	-1.4	-1.3	-2.1	-1.1	-1.4	-1.9	-2.2	-2.3
HbA1C	0.8	0.9	4.3	-1.0	-1.3	0.3	1.4	2.1	-0.6	-0.3	-0.2	0.4	0.0	0.3	-1.6	0.1	-0.4	0.2	-0.9	-1.2
Waist Hip Ratio (WHR)	0.8	3.4	17.8	-2.5	-2.9	-0.4	2.2	4.2	-0.4	-0.0	1.2	-0.4	0.8	0.2	-3.2	0.3	-0.1	-0.5	-1.6	-2.3
Lung FVC	0.8	4.0	15.2	-0.4	0.2	-1.0	-2.2	-3.9	-2.5	-2.4	-3.0	-1.6	-2.5	-2.2	0.2	-1.7	-2.0	-1.8	-1.5	-0.8
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.7	-0.7	-0.8	-0.9	-1.1	-0.5	-1.2	-1.5	-1.6	-1.0	-0.4	-0.8	-1.1	-1.3	-0.7	-0.8	-0.2	-1.2
Vitamin and mineral supplements	0.8	1.1	2.0	1.0	0.8	1.3	0.8	0.8	1.1	0.8	1.1	1.1	1.3	1.2	0.2	1.1	1.2	0.9	1.4	0.9
Impedance of leg (right)	0.8	4.0	14.9	0.6	-0.3	2.6	3.9	2.9	0.9	1.0	0.8	2.3	2.6	2.3	-0.8	2.6	1.9	2.4	0.7	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	4.2	-1.6	-1.4	-1.0	-0.9	0.1	-1.3	-1.1	-0.5	-1.5	-1.7	-1.6	-1.3	-1.1	-1.6	-2.0	-1.3	-1.0
Medication: Ramipril	0.8	1.1	5.1	-0.8	-1.0	0.2	1.4	2.1	0.0	0.6	1.1	0.4	0.7	0.5	-2.2	-0.2	0.5	-0.3	-0.4	-1.5
Pulse wave Arterial Stiffness index	0.8	1.0	2.3	-1.1	-1.0	-1.1	-0.7	-0.2	-0.6	-0.7	-0.0	-1.3	-1.5	-1.3	-0.6	-0.7	-1.1	-1.3	-1.2	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.1	0.5	0.2	1.4	1.8	1.0	1.1	1.2	0.8	1.4	1.2	1.3	0.0	1.4	1.2	1.1	1.0	0.1
Leg fat mass (right)	0.8	3.0	13.9	-0.8	-1.0	0.0	2.8	3.7	1.7	2.0	2.4	1.2	2.0	1.5	-0.8	1.1	1.4	1.6	-0.2	-1.0
Ever had bowel cancer screening	0.8	0.9	1.8	-1.0	-0.9	-1.1	-0.4	-1.3	-0.9	-0.5	-0.2	-1.1	-1.2	-1.0	-0.8	-0.9	-0.9	-1.2	-0.2	-1.3
Mineral and other dietary supplements	0.8	1.1	2.4	1.0	0.7	1.6	1.3	0.7	0.8	0.6	0.7	1.3	1.3	1.2	-0.0	1.2	1.3	1.2	1.4	0.2
Commuting to job workplace: Public transport	0.8	1.0	1.9	-1.3	-1.3	-1.2	-0.6	-0.0	-1.1	-1.1	-0.2	-1.4	-0.9	-1.0	-0.9	-0.9	-1.1	-1.1	-0.5	-1.0
Leg fat mass (left)	0.8	3.0	13.1	-0.6	-0.8	0.0	2.7	3.6	1.8	2.1	2.5	1.2	2.0	1.6	-0.7	1.1	1.5	1.7	0.0	-0.8
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.2	-1.4	-1.4	-1.5	-1.1	0.3	-1.2	-1.1	-1.2	-1.0	-1.0	-1.1	-0.7	-1.4	-1.3	-1.1	-1.4	-0.6
Ever used hormone-replacement therapy (HRT)	0.7	0.8	1.5	-0.9	-0.8	-1.2	-1.2	-0.4	-0.8	-1.0	-0.9	-1.0	-1.0	-1.0	-0.3	-1.0	-1.0	-0.9	-0.8	-0.6
Pack years adult smoking proportion	0.7	1.1	2.0	0.7	0.5	0.7	0.8	1.2	1.1	1.1	1.0	1.2	1.4	1.2	0.8	1.0	1.0	1.2	0.8	1.4
Average weekly fortified wine intake	0.7	0.8	3.1	-0.1	0.4	-1.4	-1.6	-1.8	-0.2	-0.1	0.2	-1.2	-1.0	-0.8	1.0	-0.9	-0.7	-0.6	0.0	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	6.9	-0.6	-1.0	0.3	1.2	2.6	0.3	0.0	0.7	-0.1	0.8	0.2	-1.5	0.4	0.3	0.4	-0.4	-1.0
Hair/balding pattern: Pattern 2	0.7	0.9	2.5	-0.8	-0.8	-1.6	-1.6	-0.5	-0.4	-0.8	-1.0	-1.0	-1.1	-1.1	0.6	-1.1	-1.1	-0.7	-0.8	0.0
Mouth/teeth dental problems	0.7	1.0	2.8	1.6	1.3	0.9	-1.1	-1.7	0.5	0.0	-1.2	0.7	-0.1	0.2	1.5	0.1	0.3	0.5	1.4	1.4
Trunk fat-free mass	0.7	4.2	9.3	-1.9	-0.6	-2.5	-1.6	-2.9	-2.0	-0.7	-0.9	-2.3	-2.7	-2.0	-0.9	-2.3	-1.9	-3.0	-2.5	-1.9
Hair/balding pattern: Pattern 3	0.7	1.0	4.0	-0.3	-0.6	0.9	1.9	2.0	0.2	0.2	0.8	0.6	1.2	0.9	-1.3	0.9	0.7	0.8	0.5	-0.9
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	18.8	1.2	2.0	0.3	-1.2	-4.3	-0.9	-0.6	-1.7	-0.4	-1.4	-0.8	1.7	-0.2	-0.5	-0.6	-0.2	0.8
Trunk predicted mass	0.7	4.2	9.1	-1.9	-0.6	-2.5	-1.6	-2.8	-2.0	-0.7	-0.9	-2.2	-2.7	-2.0	-0.9	-2.3	-1.9	-3.0	-2.5	-1.9
Hair/balding pattern: Pattern 4	0.7	1.7	3.4	1.2	1.0	1.8	1.3	1.3	1.4	1.4	1.6	1.4	1.2	1.3	0.1	1.5	1.3	1.0	1.2	1.0
Peak expiratory flow (PEF)	0.7	1.6	6.5	1.8	2.4	0.6	-0.2	-2.5	0.7	0.8	-0.2	0.6	-0.2	0.2	2.3	0.7	0.5	0.8	0.4	1.4
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.5	-1.3	-1.3	-1.1	-0.7	0.3	-0.7	-0.4	0.4	-1.1	-0.9	-0.9	-1.3	-1.1	-1.0	-1.6	-0.5	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.1	-1.1	-1.4	-1.0	-0.7	0.8	-0.4	-0.8	-0.8	-1.0	-0.9	-1.1	-1.0	-0.9	-0.9	-0.9	-0.8	-1.3
Qualifications: College or University degree	0.7	2.3	8.8	-0.4	0.3	-1.3	-2.0	-3.0	-1.1	-1.0	-0.9	-1.9	-2.3	-1.8	0.3	-1.3	-1.6	-2.0	-0.5	-0.3
Medication: Omeprazole	0.7	0.8	3.1	-1.2	-1.5	-0.3	0.7	1.6	-0.5	-0.4	-0.2	-0.2	0.2	-0.1	-1.8	-0.4	-0.2	-0.4	-0.7	-1.4
Illnesses of siblings: Diabetes	0.7	0.9	2.9	-1.2	-1.2	-1.7	-1.3	-0.2	-0.6	-0.6	-0.3	-1.1	-0.7	-0.8	-0.2	-1.2	-1.0	-1.0	0.0	-0.4
Medication: Aspirin	0.7	1.0	2.4	-1.5	-1.6	-0.7	-0.1	1.5	-0.6	-0.6	0.4	-1.2	-0.5	-0.6	-1.5	-0.5	-0.7	-1.0	-0.7	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	5.1	0.2	0.4	-0.5	-1.9	-2.2	-1.0	-1.3	-1.5	-1.2	-1.6	-1.3	-0.2	-1.3	-0.9	-1.3	-0.1	-0.6
Leg predicted mass (right)	0.7	3.8	8.3	-1.7	-0.5	-2.9	-2.2	-2.4	-1.5	-0.7	-0.6	-2.4	-2.5	-2.1	-0.3	-2.4	-2.0	-2.7	-2.1	-1.2
Wears glasses or contact lenses	0.7	0.8	2.5	0.7	0.6	0.4	0.6	1.0	1.4	1.2	1.6	0.6	0.9	0.7	0.6	0.8	0.8	0.9	0.8	0.9
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.9	-0.8	-1.3	0.2	1.3	2.0	-0.1	0.0	0.2	0.2	0.6	0.3	-1.7	0.0	0.3	0.1	-0.3	-1.4
Triglycerides	0.6	1.1	1.9	1.1	1.1	1.4	1.1	0.7	0.8	0.8	0.7	1.3	1.3	1.3	0.2	1.2	1.3	1.2	0.6	0.7
Cardiovascular Disease	0.6	2.0	7.2	-0.1	-0.3	0.6	2.7	2.6	1.3	1.5	1.3	1.4	1.7	1.4	-0.2	1.5	1.3	1.8	-0.3	-0.4
Leg fat-free mass (left)	0.6	3.2	7.6	-1.8	-0.6	-2.8	-1.8	-1.9	-1.4	-0.5	-0.5	-2.2	-2.3	-1.9	-0.4	-2.2	-1.8	-2.5	-2.1	-1.3
High blood pressure (mother)	0.6	0.8	1.3	-0.9	-0.7	-0.9	-0.8	-0.6	-1.1	-1.1	-1.0	-0.9	-0.8	-1.0	-0.9	-1.1	-0.9	-1.0	-0.5	-1.1
Leg predicted mass (left)	0.6	3.0	7.2	-1.7	-0.5	-2.7	-1.8	-1.9	-1.3	-0.4	-0.4	-2.1	-2.2	-1.9	-0.3	-2.1	-1.7	-2.4	-2.0	-1.2
Alcohol usually taken with meals	0.6	1.0	2.9	-0.0	0.2	-0.6	-1.5	-1.7	-0.7	-0.8	-1.3	-0.9	-1.5	-1.2	0.9	-0.8	-1.2	-0.9	-0.6	0.4
Pain all over the body in last month	0.6	0.6	2.3	-0.9	-1.2	-0.3	-0.1	1.3	-0.7	-0.8	-0.5	-0.4	-0.2	-0.4	-1.5	-0.6	-0.5	-0.7	-0.5	-1.0
Alcohol intake versus 10 years previously	0.6	1.0	3.2	0.1	-0.1	0.5	1.4	1.8	0.8	0.8	1.1	0.8	1.6	1.2	-0.1	0.8	1.0	1.2	0.8	0.3
Pulse wave reflection index	0.6	0.7	6.0	-0.6	-1.0	0.4	0.7	2.5	0.9	0.6	1.0	0.4	-0.0	0.2	-0.6	0.7	0.1	-0.1	-0.6	-0.2
Gout (self-reported)	0.6	0.8	2.6	-0.3	0.1	-1.1	-1.6	-1.1	-0.6	-0.7	-0.3	-1.2	-1.0	-0.9	-0.2	-1.2	-0.8	-1.2	-0.4	-0.2
Pulse wave peak to peak time	0.6	0.7	1.6	1.0	1.0	0.8	0.6	-0.0	0.5	0.6	-0.0	1.2	1.3	1.1	0.6	0.5	1.0	1.0	0.9	1.0
Family relationship satisfaction	0.6	0.7	1.9	-0.9	-0.9	-0.4	0.1	0.6	-0.6	-0.6	-0.4	-0.8	-1.0	-0.9	-1.2	-0.4	-0.8	-0.9	-1.3	-1.4
Medication: Aspirin	0.6	0.7	3.0	-1.3	-1.4	-0.4	0.3	1.7	-0.4	-0.4	0.5	-0.9	-0.1	-0.3	-1.5	-0.2	-0.3	-0.6	-0.5	-1.1
Whole body fat-free mass	0.6	3.4	7.3	-1.8	-0.4	-2.5	-1.6	-2.5	-1.6	-0.4	-0.5	-2.1	-2.4	-1.8	-0.6	-2.1	-1.7	-2.7	-2.2	-1.5
Leg fat-free mass (right)	0.6	3.4	7.6	-1.6	-0.4	-2.8	-2.1	-2.3	-1.4	-0.5	-0.5	-2.3	-2.4	-2.0	-0.2	-2.2	-1.8	-2.5	-2.0	-1.1
Arm fat percentage (left)	0.6	2.5	14.4	-0.5	-0.9	-0.0	2.2	3.8	1.7	1.6	2.3	0.9	1.8	1.2	-0.6	1.0	1.2	1.7	0.0	-0.6
Long-standing illness, disability or infirmity	0.6	1.0	3.4	-1.4	-1.6	-1.1	-0.2	1.2	-0.7	-0.6	-0.1	-0.7	-0.2	-0.5	-1.9	-1.2	-0.6	-0.8	-0.5	-1.4
Qualifications: nursing, teaching	0.6	0.9	2.1	-1.1	-0.8	-1.5	-1.3	-0.6	-0.3	-0.1	-0.2	-1.1	-1.3	-0.9	-0.2	-1.1	-1.0	-1.4	-0.6	-0.6
Whole body water mass	0.6	3.2	7.1	-1.7	-0.4	-2.5	-1.6	-2.5	-1.5	-0.3	-0.5	-2.1	-2.4	-1.8	-0.6	-2.0	-1.6	-2.7	-2.1	-1.5
Medication: Atorvastatin	0.6	0.7	2.5	-1.1	-1.3	-0.3	0.8	1.6	-0.2	0.1	0.7	-0.5	-0.0	-0.1	-1.6	-0.2	-0.2	-0.6	-0.8	-1.1
Commuting to job workplace: Cycle	0.6	0.7	3.0	1.1	1.3	-0.3	-0.9	-1.7	0.8	0.3	-0.0	0.0	-0.2	-0.1	1.7	0.0	0.2	0.7	0.8	0.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.4	-0.9	-0.8	-0.7	-0.8	-0.1	-1.0	-1.1	-0.6	-1.2	-1.1	-1.0	-0.6	-0.7	-1.1	-1.1	-0.9	-0.7
Systolic blood pressure, automated reading	0.5	1.3	7.1	-0.3	-0.5	0.0	1.2	2.3	1.3	1.3	2.7	0.3	1.0	0.8	-0.9	0.5	0.8	0.4	0.8	-0.2
Townsend deprivation index at recruitment	0.5	0.7	3.6	-0.9	-1.1	0.0	1.4	1.9	0.1	0.5	0.9	0.3	0.6	0.6	-1.1	0.3	0.3	0.2	-0.5	-0.9
Trunk fat mass	0.5	1.9	10.3	-1.3	-1.3	-0.8	2.1	3.2	1.0	1.4	2.0	0.3	1.2	0.7	-0.9	0.5	0.7	1.0	-0.9	-1.2
Waist circumference	0.5	1.7	9.1	-1.3	-1.3	-0.7	1.8	3.0	0.9	1.4	2.1	0.2	1.0	0.6	-1.3	0.3	0.6	0.4	-0.6	-1.2
Forced vital capacity (FVC)	0.5	1.9	15.1	0.6	1.5	-0.1	-1.2	-3.9	-1.2	-0.8	-1.8	-0.7	-1.7	-1.0	1.1	-0.4	-0.8	-1.0	-0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	4.7	-0.3	-0.9	0.7	1.0	2.2	0.7	0.5	0.3	0.7	0.7	0.6	-0.9	0.6	0.5	0.5	0.2	-0.6
Illnesses of siblings	0.5	0.7	4.0	0.7	1.0	0.5	-0.9	-2.0	-0.3	-0.4	-1.0	-0.3	-1.0	-0.6	0.9	0.1	-0.4	-0.6	-0.0	0.6
Arm fat percentage (right)	0.5	2.1	13.2	-0.6	-1.0	-0.1	1.9	3.6	1.5	1.4	2.1	0.8	1.6	1.0	-0.7	0.8	1.0	1.4	-0.1	-0.7
Falls in the last year	0.5	0.7	2.6	-1.1	-1.3	-0.7	-0.2	1.1	-0.4	-0.6	0.3	-0.9	-0.3	-0.6	-1.6	-0.7	-0.5	-0.8	-0.0	-1.4
Depression (self-reported)	0.5	0.6	2.0	-1.0	-1.3	-0.5	0.3	0.7	-0.4	-0.6	-0.6	-0.6	-0.7	-0.8	-0.9	-0.3	-0.7	-0.4	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	13.0	0.5	1.3	0.1	-1.1	-3.6	-1.4	-0.9	-1.8	-0.7	-1.6	-1.0	0.8	-0.5	-0.8	-1.0	-0.6	0.1
Length of working week for main job	0.5	0.6	2.4	-1.0	-1.1	-0.4	0.1	1.3	-0.3	-0.2	0.8	-0.7	-0.3	-0.4	-1.5	-0.4	-0.4	-0.9	-0.5	-1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.9	-0.1	-0.3	0.3	1.1	1.7	0.9	0.7	0.9	0.5	0.9	0.7	-0.2	0.8	0.7	0.9	0.3	-0.2
Blood clot in the leg (DVT)	0.5	0.6	1.2	-1.0	-0.9	-0.6	-0.5	0.2	-0.9	-1.0	-0.4	-1.1	-1.0	-0.9	-0.6	-0.5	-1.0	-0.9	-0.9	-0.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.3	-0.5	-0.9	0.7	1.2	1.0	-0.3	-0.1	0.1	0.1	0.1	0.1	-1.8	0.3	0.2	-0.3	-0.1	-1.6
Forced vital capacity (FVC), Best measure	0.5	1.9	12.2	0.2	1.0	-0.1	-1.2	-3.5	-1.7	-1.2	-2.1	-0.8	-1.7	-1.1	0.6	-0.7	-1.0	-1.2	-1.1	-0.1
Exposure to tobacco smoke outside home	0.5	0.7	2.7	-1.0	-1.1	0.3	1.6	1.3	-0.3	-0.0	0.6	0.1	0.6	0.4	-1.2	0.6	0.3	0.1	-0.2	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	4.7	1.1	1.6	0.3	-0.4	-2.2	-0.0	0.1	-0.1	-0.1	-0.0	0.1	0.7	-0.0	0.4	0.1	1.0	0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	3.1	0.4	0.9	-0.7	-1.4	-1.8	-0.2	-0.1	-0.1	-0.6	-1.0	-0.8	0.7	-0.8	-0.6	-0.7	-0.2	0.6
Hypertension (Self-reported)	0.5	1.4	5.4	-1.6	-1.5	-0.9	1.8	2.3	-0.0	0.5	1.1	-0.2	0.3	-0.0	-1.7	-0.0	-0.1	0.0	-1.4	-1.9
Handedness (chirality/laterality): Left-handed	0.5	0.7	1.6	-1.2	-1.2	-1.1	-0.2	1.0	-0.4	-0.0	0.4	-0.5	-0.3	-0.4	-1.1	-0.9	-0.5	-0.8	-1.3	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.1	0.7	0.8	0.8	0.8	-0.6	0.3	0.5	0.2	0.8	0.7	0.8	0.9	1.1	0.6	0.7	0.6	1.0
Back pain experienced in last month	0.5	0.7	1.5	1.0	0.9	0.8	0.6	0.4	0.9	0.8	0.9	0.9	1.2	1.0	0.1	0.6	1.1	0.8	1.2	0.6
Osteoporosis (self-reported)	0.5	0.7	2.1	0.3	-0.2	1.1	1.2	1.4	1.0	0.9	0.8	0.9	0.5	0.8	-0.6	0.6	0.8	0.6	0.7	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.2	0.8	0.9	0.6	0.3	-0.2	0.8	0.9	0.5	0.9	1.1	1.0	0.6	0.5	1.0	0.7	1.1	1.0
Ever depressed for a whole week	0.5	0.6	2.2	-0.9	-1.3	0.3	1.1	1.2	-0.3	-0.1	-0.5	0.0	-0.1	-0.0	-1.2	0.2	-0.1	-0.1	-0.5	-1.5
Vascular/heart problems diagnosed by doctor	0.5	1.3	4.8	1.5	1.5	0.8	-1.3	-2.2	0.3	-0.2	-0.9	0.4	-0.0	0.3	1.9	0.3	0.3	0.3	1.4	1.8
Pack years of smoking	0.5	0.7	1.6	0.4	0.3	0.3	0.6	1.3	1.0	1.0	1.1	0.9	1.2	0.9	0.6	0.7	0.7	0.9	0.6	1.2
Sensitivity / hurt feelings	0.4	0.8	4.0	0.5	0.4	-0.4	-0.5	-0.7	1.0	0.8	0.4	0.5	0.4	0.4	2.0	0.6	0.1	0.5	1.0	1.9
High blood pressure	0.4	1.1	4.7	-1.2	-1.2	-0.6	1.7	2.2	0.2	0.6	1.3	-0.1	0.3	0.1	-1.5	0.1	0.0	0.1	-1.0	-1.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.5	-1.0	-0.9	-0.4	0.2	0.7	-0.5	-0.3	0.2	-0.6	-0.5	-0.5	-1.2	-0.5	-0.5	-0.7	-0.7	-1.2
Body mass index (BMI)	0.4	1.7	8.3	-0.3	-0.6	-0.1	1.5	2.9	1.7	1.7	2.0	0.9	1.5	1.1	-0.3	0.6	1.1	1.3	0.3	-0.4
Had other major operations	0.4	0.5	3.0	-0.2	0.2	-0.7	-1.1	-1.7	-0.7	-0.6	-0.5	-0.8	-0.7	-0.6	0.0	-0.8	-0.5	-0.8	0.1	-0.2
Worrier / anxious feelings	0.4	0.7	1.6	-1.2	-1.3	-1.2	-0.7	0.6	-0.2	-0.3	-0.1	-1.0	-0.5	-0.6	-1.0	-1.0	-0.6	-1.0	-0.2	-1.0
Number of live births	0.4	0.6	1.6	-0.9	-0.8	-0.5	-0.3	0.5	-0.5	-0.3	0.4	-0.7	-0.8	-0.7	-1.2	-0.8	-0.6	-1.2	-0.7	-1.0
Asthma	0.4	0.7	1.8	-1.1	-1.1	-1.2	-1.0	-0.0	-0.3	-0.1	0.3	-1.0	-1.1	-0.9	-0.3	-0.8	-1.0	-1.4	-0.6	-0.3
Headache pain in last month	0.4	0.7	2.9	-0.6	-0.7	0.3	1.4	1.6	-0.1	0.3	0.9	0.0	0.8	0.4	-1.7	0.2	0.4	-0.0	-0.2	-1.2
High blood pressure (siblings)	0.4	0.6	1.8	-1.0	-1.1	-1.3	-0.3	0.4	-0.9	-0.7	-0.7	-0.5	-0.1	-0.4	-0.6	-1.1	-0.6	-0.2	-0.9	-0.8
Wheeze or whistling in the chest in last year	0.4	0.7	3.0	-1.3	-1.4	-0.8	0.5	1.7	-0.2	-0.0	0.5	-0.3	0.4	0.1	-1.4	-0.4	-0.1	-0.4	-0.7	-1.1
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.6	-0.1	-0.0	0.6	1.3	1.0	0.3	0.4	1.1	0.2	0.7	0.4	-0.8	0.8	0.6	0.5	0.0	-0.6
Medication: Blood pressure	0.4	0.8	2.7	-1.0	-1.0	-0.3	1.4	1.7	-0.0	0.6	0.8	0.2	0.3	0.2	-1.7	-0.1	0.1	-0.2	-0.7	-1.4
Whole body fat mass	0.4	1.7	8.4	-0.9	-0.9	-0.6	2.0	2.9	1.2	1.5	2.0	0.5	1.3	0.9	-0.6	0.6	0.9	1.2	-0.6	-1.0
Pulse rate, automated reading	0.4	1.1	3.1	-1.5	-1.0	-1.8	-0.0	-1.2	-1.4	-0.7	0.1	-1.4	-0.8	-1.0	-0.6	-0.9	-1.0	-0.9	-1.0	-1.3
Leg pain on walking	0.4	0.5	1.3	-0.4	-0.4	-0.5	-1.1	-0.6	-0.8	-1.0	-1.1	-0.7	-0.6	-0.6	-0.3	-0.9	-0.6	-0.7	-0.2	-0.3
Illnesses of father: Heart disease	0.4	0.6	1.4	-0.8	-0.8	-0.6	-0.3	-0.2	-1.1	-1.0	-0.6	-0.7	-0.5	-0.6	-1.1	-0.9	-0.7	-0.6	-0.1	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.1	-0.8	-0.4	-1.5	-0.7	-0.7	-0.3	-0.2	0.2	-1.2	-1.1	-0.9	-0.1	-0.7	-0.8	-0.9	-1.0	-0.8
Breast cancer (self-reported)	0.4	0.5	2.1	0.6	0.9	-0.5	-1.5	-1.2	0.0	-0.0	-0.6	-0.1	-0.3	-0.3	1.0	-0.7	-0.2	-0.3	-0.1	1.1
Alcohol drinker status: Never	0.4	0.5	1.9	-0.2	-0.1	0.5	1.4	1.1	0.1	0.6	0.8	0.8	1.0	0.9	-0.8	0.5	0.7	0.5	0.1	-0.4
Basal metabolic rate	0.4	2.1	4.9	-1.6	-0.5	-2.2	-1.0	-1.7	-1.1	-0.0	-0.1	-1.7	-1.8	-1.4	-0.5	-1.7	-1.3	-2.1	-1.9	-1.4
Irritability	0.4	0.6	2.2	-1.0	-1.2	-0.3	0.9	1.4	0.2	0.3	0.9	-0.3	0.2	0.1	-1.3	0.0	0.2	-0.1	-0.0	-1.5
Heart disease (siblings)	0.4	0.5	2.3	-0.1	-0.3	0.0	0.9	1.5	0.8	0.7	1.3	0.5	1.0	0.7	-0.1	0.6	0.6	0.8	0.4	0.1
Schizophrenia (2018)	0.3	0.7	1.8	0.5	-0.0	1.0	0.5	1.3	1.2	0.9	0.1	1.1	1.0	1.1	-0.2	0.5	1.1	0.9	0.9	0.0
Worry (Nagel 2018)	0.3	0.6	3.2	-0.9	-1.3	-0.1	0.6	1.8	0.5	0.6	0.8	-0.0	0.0	0.1	-1.5	-0.1	0.1	-0.5	-0.2	-1.1
Crohns Disease (2017)	0.3	0.6	3.3	-0.4	-0.8	0.5	1.0	1.8	0.4	0.4	0.4	0.7	1.1	0.9	-0.5	0.6	0.6	0.5	0.3	-0.1
Ulcerative Colitis (UC)	0.3	0.6	1.9	-0.3	-0.4	-0.5	-1.2	-0.7	-0.7	-1.0	-1.4	-0.6	-1.0	-0.8	-0.4	-0.9	-0.7	-0.8	-0.5	-0.7
Body Mass Index (BMI) (2010)	0.3	0.5	2.4	0.6	0.7	-0.2	-1.1	-1.0	0.4	-0.0	-0.3	-0.0	-0.4	-0.3	1.6	0.0	-0.3	0.2	0.3	1.3
Fasting Glucose	0.3	0.3	1.2	-0.1	-0.5	-0.8	-0.7	0.3	0.3	-0.2	-0.6	-0.2	-1.1	-0.3	-0.1	-0.9	-0.8	0.2	-0.2	-0.7
HDL Cholesterol	0.3	0.4	2.3	-0.4	-0.5	-0.0	1.1	0.7	0.5	0.8	1.5	-0.0	0.3	0.3	-0.7	0.3	0.4	-0.0	0.5	-0.8
Rheumatoid Arthritis	0.3	0.4	1.6	-0.8	-1.0	-0.3	0.3	0.9	-0.4	-0.3	-0.3	-0.2	-0.4	-0.4	-1.1	-0.5	-0.4	-0.4	-0.9	-1.2
Schizophrenia (2014)	0.3	0.6	1.6	0.5	0.0	0.9	0.4	1.2	0.9	0.6	-0.3	1.0	1.2	1.1	0.1	0.5	1.0	1.0	0.8	0.3
Ulcerative Colitis	0.3	0.4	1.5	-0.4	-0.5	-0.5	-0.6	-0.5	-0.5	-0.8	-0.7	-0.8	-0.8	-0.7	-0.7	-0.7	-0.5	-0.5	-0.1	-1.2
BMI	0.3	1.7	4.7	0.7	0.6	0.1	0.6	1.2	2.2	2.1	1.9	1.1	1.4	1.3	1.1	0.7	1.4	1.4	1.3	1.0
Lung FEV1/FVC ratio	0.3	1.8	6.1	1.8	2.1	0.9	-0.9	-2.5	0.8	0.6	-0.1	0.6	0.2	0.5	2.3	0.6	0.6	0.5	1.5	2.1
Medication: Metformin	0.3	0.4	1.0	-0.7	-0.7	-0.6	-0.6	0.8	-0.5	-0.3	-0.0	-0.5	-0.4	-0.5	-1.0	-0.9	-0.6	-1.0	-0.6	-0.2
Diabetes (father)	0.3	0.4	1.7	0.3	0.6	-0.6	-0.7	-1.3	-0.5	-0.5	-1.3	-0.2	-0.2	-0.3	1.1	-0.5	-0.4	0.4	-0.3	0.4
Relative age voice broke	0.3	0.4	1.2	0.5	0.2	0.6	0.9	0.5	0.3	0.3	0.3	0.7	1.1	0.7	0.1	0.5	0.7	1.1	0.8	0.2
Qualifications: None of the above	0.3	0.7	3.7	0.3	-0.1	0.9	1.0	1.9	0.3	0.2	0.5	0.8	1.3	0.8	-0.7	0.5	0.8	0.9	0.0	0.2
Happiness	0.3	0.4	1.4	0.1	0.0	0.7	1.1	1.2	0.5	0.5	0.3	0.5	0.5	0.5	-0.5	0.7	0.6	0.5	-0.5	-0.5
Arm fat mass (right)	0.3	1.1	5.8	-0.8	-0.7	-0.6	1.4	2.4	1.1	1.4	1.8	0.4	0.9	0.6	-0.6	0.3	0.6	0.7	-0.5	-0.8
Birth weight	0.3	0.7	6.1	0.4	0.7	-0.2	-0.9	-2.5	-0.4	-0.1	-0.5	-0.4	-1.1	-0.8	0.1	-0.7	-0.4	-1.0	0.3	-0.4
Arm fat-free mass (right)	0.3	1.6	4.0	-1.6	-0.6	-1.7	-0.5	-1.3	-0.9	0.2	0.1	-1.4	-1.5	-1.0	-1.0	-1.3	-0.9	-2.0	-1.8	-1.6
Number of full brothers	0.3	0.3	1.1	0.2	0.2	-0.4	-0.8	-1.0	-0.4	-0.7	-1.1	-0.3	-0.5	-0.6	0.7	-0.4	-0.6	-0.0	-0.1	0.3
Number of children fathered	0.3	0.3	1.4	-0.4	-0.6	0.2	-0.2	0.4	-0.3	-0.4	0.3	-0.6	-0.7	-0.5	-1.2	-0.3	-0.4	-1.1	-0.2	-0.7
Arm predicted mass (right)	0.3	1.5	4.0	-1.5	-0.5	-1.7	-0.5	-1.4	-0.9	0.2	0.1	-1.3	-1.4	-1.0	-0.9	-1.3	-0.9	-2.0	-1.6	-1.6
Comparative height size at age 10	0.3	1.6	8.9	-0.3	0.9	-1.0	-0.8	-3.0	-1.0	0.1	-0.1	-1.2	-1.9	-1.2	-0.2	-1.0	-0.9	-2.0	-1.4	-0.5
Chest pain or discomfort	0.3	0.4	1.5	-1.0	-1.1	-0.7	0.2	0.3	-0.6	-0.6	-0.2	-0.6	-0.2	-0.5	-0.9	-0.4	-0.5	-0.5	-0.4	-1.2
Osteoarthritis (self-reported)	0.3	0.3	1.8	-0.5	-0.7	-0.4	0.3	0.4	0.0	0.3	0.4	-0.1	-0.1	-0.1	-1.4	-0.7	0.0	-0.4	0.0	-1.3
Arm fat mass (left)	0.3	1.2	6.1	-0.8	-0.7	-0.5	1.5	2.5	1.1	1.4	1.8	0.4	1.0	0.7	-0.6	0.4	0.7	0.7	-0.4	-0.8
Mother’s age at death	0.3	0.4	1.2	0.7	0.6	1.1	0.4	0.6	0.8	0.8	0.8	0.6	0.3	0.5	-0.4	0.4	0.8	0.2	-0.0	-0.0
Diastolic blood pressure, automated reading	0.3	0.8	3.5	-0.4	-0.4	-0.2	1.7	1.3	0.6	1.0	1.9	0.3	1.0	0.7	-0.5	0.7	0.6	0.7	0.3	-0.5
Basal cell carcinoma (self-reported)	0.3	0.4	1.3	-1.0	-1.1	-0.9	-0.2	1.0	-0.4	-0.5	-0.1	-0.6	-0.3	-0.4	-0.4	-0.5	-0.6	-0.3	-0.8	-0.4
Impedance of whole body	0.3	1.4	5.5	0.2	-0.4	1.4	2.3	2.1	0.3	0.0	0.3	1.1	1.5	1.0	-0.4	1.7	0.8	1.6	0.1	-0.0
Arm predicted mass (left)	0.3	1.3	3.3	-1.5	-0.5	-1.6	-0.4	-1.1	-0.8	0.3	0.2	-1.2	-1.4	-0.9	-0.9	-1.2	-0.8	-1.8	-1.6	-1.5
Bipolar Disorder or Schizophrenia	0.2	0.4	2.2	-0.7	-1.2	-0.2	0.1	1.5	0.1	0.0	0.1	-0.1	0.2	0.2	-1.3	-0.4	0.1	-0.2	0.0	-1.1
Irritable Bowel Disease (IBD)	0.2	0.5	1.2	-0.9	-1.1	-0.3	-0.4	0.8	-0.6	-0.8	-1.0	-0.3	-0.3	-0.3	-0.9	-0.6	-0.5	-0.6	-0.6	-0.8
Ovarian Cancer	0.2	0.3	1.3	-0.6	-0.5	0.1	0.9	0.9	-0.1	0.3	0.7	0.1	0.0	0.1	-1.1	0.1	-0.0	-0.4	-0.7	-0.8
Prostate Cancer	0.2	0.2	0.9	-0.2	0.1	-0.8	-0.7	-1.0	-0.0	0.2	0.3	-0.4	-0.6	-0.5	0.3	-0.6	-0.3	-0.6	-0.1	0.1
Bipolar Disorder (2011)	0.2	0.2	0.8	-0.3	-0.2	-0.0	0.6	0.6	-0.1	-0.0	0.6	-0.3	0.1	-0.0	-0.8	0.1	0.1	0.0	-0.2	-0.9
Crohns Disease (2012)	0.2	0.4	1.0	-0.3	-0.4	0.3	0.9	1.0	0.3	0.6	0.6	0.5	0.9	0.8	-0.9	0.2	0.7	0.1	0.3	-0.4
Primary Biliary Cirrhosis	0.2	0.2	1.0	0.3	0.1	0.1	0.7	-0.2	0.3	0.3	-0.3	0.6	0.5	0.5	0.7	0.5	0.4	1.0	0.5	0.1
Heel T-Score	0.2	1.9	8.1	0.7	0.8	-0.1	-2.3	-2.9	-0.9	-1.6	-1.9	-1.2	-1.7	-1.4	1.3	-0.6	-1.2	-0.9	0.4	0.8
Smoking Status	0.2	0.5	2.0	0.3	0.3	0.4	0.8	0.6	0.7	1.0	1.4	0.5	0.9	0.8	-0.5	0.4	0.9	0.5	0.5	-0.2
Chronotype (morning person)	0.2	0.4	2.1	0.0	-0.3	0.6	0.4	1.5	-0.4	-0.7	-0.9	0.4	0.7	0.3	-0.8	0.0	0.1	0.5	-0.3	-0.1
Tanning	0.2	3.0	8.0	0.9	0.7	1.1	1.4	2.6	2.3	2.0	2.8	1.3	2.2	1.9	-0.0	1.5	1.9	1.4	2.0	1.1
Diabetes (mother)	0.2	0.2	0.7	0.6	0.3	0.1	-0.6	-0.1	0.4	0.1	-0.5	0.6	0.3	0.2	0.7	-0.1	0.2	0.3	0.7	0.8
Age when periods started (menarche)	0.2	0.4	1.1	-0.5	-0.7	0.3	0.7	0.9	-1.0	-0.9	-0.9	0.2	0.2	0.0	-0.6	-0.0	-0.3	0.3	-1.0	-0.4
Had menopause	0.2	0.2	1.1	-0.0	-0.1	-0.1	-1.1	0.6	0.3	0.1	0.4	-0.3	-0.4	-0.3	-0.5	-0.7	-0.2	-0.8	-0.0	0.3
Time employed in main current job	0.2	0.2	0.6	-0.0	0.0	-0.2	-0.8	-0.6	-0.0	-0.1	-0.1	-0.3	-0.7	-0.5	0.7	-0.1	-0.5	-0.5	0.2	0.6
Pulse rate	0.2	0.3	2.7	0.4	0.8	-0.3	0.4	-1.6	-0.1	0.3	0.6	0.0	0.3	0.3	0.6	0.2	0.4	0.4	0.8	0.1
Exposure to tobacco smoke at home	0.2	0.2	0.6	-0.1	-0.3	0.3	0.8	0.7	0.2	0.3	0.1	0.5	0.7	0.5	-0.5	0.2	0.6	0.4	0.3	-0.6
Tense / ‘highly strung’	0.2	0.3	0.8	-0.9	-0.9	-0.7	0.1	0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.4	-0.5	-0.4	-0.5	-0.4	-0.8	-0.8
Birth weight of first child	0.2	0.3	0.9	-0.6	-0.5	-0.2	-0.1	-0.7	-0.9	-0.5	-0.5	-0.5	-0.5	-0.5	-0.4	-0.3	-0.7	-0.9	-0.3	-0.2
Health satisfaction	0.2	0.2	0.9	-0.1	-0.0	-0.6	-0.5	-0.9	-0.1	-0.1	-0.4	-0.5	-0.6	-0.5	0.7	-0.3	-0.4	-0.2	-0.1	-0.1
Heart disease (mother)	0.2	0.2	0.6	-0.6	-0.8	0.0	0.7	0.7	0.1	0.3	-0.0	0.3	0.2	0.3	-0.7	0.0	0.1	-0.2	-0.1	-0.8
Overall health rating	0.2	0.4	2.0	-0.9	-1.1	-0.8	-0.2	1.4	-0.2	-0.3	0.1	-0.4	-0.0	-0.3	-0.9	-0.6	-0.4	-0.4	-0.7	-0.5
Age at last live birth	0.2	0.3	1.6	-0.1	-0.0	0.0	-0.5	-0.7	-0.2	-0.1	0.1	-0.5	-1.3	-0.8	-0.3	-0.2	-0.7	-1.1	-0.4	-0.3
Knee pain experienced in last month	0.2	0.3	1.4	0.3	0.3	0.4	0.4	0.3	0.8	0.9	1.2	0.2	0.3	0.4	-0.3	0.5	0.5	-0.0	0.7	0.1
Smoking status: Previous	0.2	0.3	1.2	-0.4	-0.1	-0.6	-0.4	-0.3	-0.3	0.0	0.2	-0.6	-0.8	-0.6	-0.1	-0.5	-0.5	-0.6	-1.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.7	0.1	0.1	0.8	1.3	0.4	0.8	1.2	1.0	0.5	0.2	0.6	-0.3	1.0	0.7	0.1	0.0	-0.5
Asthma (self-reported)	0.2	0.3	1.0	-0.7	-0.6	-0.9	-0.7	-0.2	0.1	0.3	0.7	-0.7	-0.8	-0.6	0.0	-0.4	-0.6	-1.0	-0.2	0.0
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.9	-0.2	0.0	-0.7	-0.9	-0.3	-0.0	-0.1	-0.2	-0.6	-0.6	-0.6	0.6	-0.4	-0.6	-0.4	-0.6	0.6
Medication: Lisinopril	0.2	0.2	0.7	-0.4	-0.3	0.3	0.2	0.8	-0.6	-0.7	-0.7	-0.1	-0.0	-0.2	-0.7	-0.1	-0.2	0.1	-0.8	-0.7
Ever smoked	0.2	0.4	0.8	0.8	0.7	0.5	0.6	-0.4	0.7	0.9	0.6	0.7	0.4	0.6	0.6	0.5	0.6	0.7	0.4	0.6
Arm fat-free mass (left)	0.2	1.2	3.0	-1.3	-0.3	-1.7	-0.6	-1.5	-0.8	0.3	0.0	-1.2	-1.4	-0.9	-0.5	-1.2	-0.8	-1.7	-1.6	-1.3
Average weekly beer plus cider intake	0.2	0.2	0.9	-0.0	-0.2	-0.1	0.6	1.0	0.4	0.5	0.5	0.6	0.7	0.6	-0.3	0.1	0.5	0.4	0.1	-0.1
Age started oral contraceptive pill	0.2	0.2	0.6	0.5	0.8	-0.2	-0.7	-0.8	0.3	0.3	0.1	0.0	-0.3	-0.1	0.8	-0.2	-0.0	0.0	0.0	0.6
Myopia	0.2	0.3	1.0	-0.6	-0.2	-1.0	-0.3	-0.8	-0.5	-0.3	-0.2	-0.5	-0.4	-0.5	0.1	-0.5	-0.5	-0.5	-0.3	-0.3
Pain experienced in last month	0.2	0.3	0.7	-0.3	-0.1	-0.5	-0.7	-0.8	-0.5	-0.6	-0.8	-0.5	-0.7	-0.6	0.6	-0.3	-0.7	-0.4	-0.6	0.3
Blood Eosinophil Count	0.1	0.5	1.3	1.0	1.1	0.3	-1.0	-1.1	0.4	0.3	-0.4	0.5	0.2	0.4	0.8	-0.0	0.4	0.0	0.7	1.1
Blood Platelet Count	0.1	0.8	5.2	0.9	0.5	-0.8	-1.2	-1.2	1.1	0.4	-0.3	0.2	-0.6	-0.3	2.3	-0.3	-0.2	0.8	0.7	0.9
Systolic Blood Pressure	0.1	0.6	3.1	-0.7	-0.8	-0.5	0.7	1.5	0.2	0.4	1.8	-0.4	0.2	-0.0	-1.2	-0.2	-0.0	-0.3	-0.0	-0.6
Respiratory disease	0.1	0.3	1.2	-0.7	-0.6	-1.1	-0.6	-0.0	0.0	0.1	0.5	-0.7	-0.7	-0.5	0.1	-0.5	-0.6	-0.7	-0.3	-0.1
Hair Pigment	0.1	1.7	3.7	1.6	1.2	1.9	1.3	0.1	0.6	0.4	-0.1	1.6	1.7	1.4	0.8	1.4	1.3	1.7	1.5	1.3
Average weekly spirits intake	0.1	0.1	0.9	-0.1	0.6	-0.3	0.1	-1.0	-0.3	0.4	0.5	-0.3	-0.2	-0.0	0.1	-0.1	-0.0	-0.4	-0.5	0.1
Ever had hysterectomy (womb removed)	0.1	0.2	0.6	-0.8	-0.7	-0.5	0.1	0.7	-0.4	-0.2	0.0	-0.2	0.1	-0.1	-0.5	-0.2	-0.3	-0.3	-0.6	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.0	-0.3	0.0	-0.4	-0.8	-0.4	-0.2	-0.2	0.1	-0.7	-1.0	-0.8	0.4	-0.2	-0.8	-0.9	-0.4	0.5
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.7	0.6	0.7	0.8	0.3	-0.7	0.7	0.7	0.3	0.3	0.3	0.5	0.2	0.6	0.7	0.1	0.9	0.1
Medication: Levothyroxine sodium	0.1	0.2	1.1	-0.6	-0.5	-0.2	0.3	0.8	-0.1	0.3	0.5	-0.1	0.1	-0.1	-1.0	-0.3	-0.0	-0.4	-0.4	-0.6
Chronic bronchitis/emphysema (father)	0.1	0.1	1.0	0.1	0.1	-0.5	-0.4	-0.5	0.2	0.0	-0.5	-0.1	-0.1	-0.1	1.0	-0.1	-0.1	0.4	-0.1	0.3
Number of incorrect matches in round	0.1	0.2	0.6	0.2	0.2	0.2	0.5	0.7	0.5	0.4	0.8	-0.1	0.3	0.1	-0.6	0.2	0.3	0.2	0.1	-0.4
Allergy	0.1	0.1	0.5	-0.3	-0.3	-0.3	0.3	0.6	-0.6	-0.6	-0.3	0.0	0.1	-0.2	-0.2	-0.2	-0.3	0.3	-0.7	-0.1
Weight	0.1	0.7	2.1	-1.4	-0.8	-1.5	0.6	0.9	0.2	0.9	1.1	-0.5	-0.2	-0.2	-0.6	-0.5	-0.2	-0.5	-1.3	-1.2
Impedance of arm (right)	0.1	0.3	1.0	-0.5	-0.8	-0.1	0.5	1.0	-0.5	-0.8	-0.4	-0.3	-0.1	-0.4	-0.3	0.1	-0.5	0.2	-0.6	-0.3
Hip circumference	0.1	0.6	2.9	-0.8	-0.4	-0.8	0.8	1.2	0.8	1.3	1.7	-0.1	0.3	0.2	-0.3	-0.0	0.3	0.0	-0.4	-0.6
Noisy workplace	0.1	0.1	0.8	0.0	-0.1	-0.3	-0.9	0.1	0.2	-0.2	0.0	-0.3	-0.4	-0.3	0.3	-0.3	-0.3	-0.3	0.4	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.9	-0.0	-0.0	-0.2	0.2	-1.0	-0.3	-0.3	-0.5	-0.1	-0.1	-0.0	0.2	0.1	-0.0	0.3	0.3	-0.6
Lung cancer (father)	0.1	0.2	1.8	-0.5	-0.5	-0.2	0.3	1.3	0.3	0.2	0.4	0.0	0.2	0.0	0.0	0.2	-0.1	0.2	-0.2	0.1
Impedance of arm (left)	0.1	0.3	1.2	-0.4	-0.8	0.1	0.7	1.1	-0.6	-0.9	-0.4	-0.2	0.1	-0.3	-0.6	0.2	-0.5	0.3	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.1	-0.5	-0.5	-0.2	0.2	0.8	-0.4	-0.3	-0.1	-0.2	-0.0	-0.3	-1.1	-0.5	-0.2	-0.3	-0.7	-0.8
Age at first live birth	0.1	0.2	0.7	0.4	0.5	0.3	-0.3	-0.8	0.4	0.4	0.7	-0.2	-0.6	-0.2	0.3	0.2	-0.0	-0.4	0.4	0.3
Migraine (self-reported)	0.1	0.1	0.5	-0.3	-0.5	0.0	0.5	0.6	0.1	0.0	0.5	-0.0	0.1	0.0	-0.7	0.0	0.0	-0.1	0.3	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.7	0.2	0.3	-0.5	-0.7	-0.4	0.5	0.3	0.0	-0.2	-0.5	-0.4	0.8	-0.2	-0.2	-0.0	0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	0.3	0.4	0.5	-0.1	-0.1	0.1	0.3	-0.1	0.6	0.3	0.4	-0.1	0.0	0.3	-0.2	0.3	0.6
Hearing aid user	0.1	0.1	0.3	0.5	0.5	0.3	-0.1	-0.1	0.3	0.4	0.3	0.4	0.3	0.4	0.2	0.1	0.4	0.1	0.4	0.5
Tinnitus: Yes, now most or all of the time	0.1	0.2	1.0	-0.4	-0.5	-0.0	0.1	1.0	-0.1	0.0	-0.1	0.1	-0.1	-0.0	-0.3	-0.1	-0.3	-0.3	-0.9	0.3
Allergy or Eczema	0.0	0.1	1.2	0.1	0.3	-0.1	-0.3	-1.1	0.1	0.1	-0.2	-0.3	-0.4	-0.2	0.0	-0.1	-0.0	-0.4	0.3	-0.3
Hypothyroidism (self reported)	0.0	0.1	0.8	-0.2	-0.2	-0.0	0.0	0.3	-0.5	-0.4	-0.9	0.2	0.2	-0.1	-0.2	-0.3	-0.1	0.1	-0.6	-0.1
Past tobacco smoking	0.0	0.1	0.4	0.1	0.0	0.1	-0.3	-0.2	-0.2	-0.5	-0.6	0.1	0.2	0.0	0.3	0.0	-0.0	0.1	0.7	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.1	0.0	0.0	-0.2	-0.0	-0.0	-0.1	-0.1	-0.0	-0.2	-0.2	-0.2	-0.2	-0.3	-0.1	-0.0	-0.2	-0.4

Hub : Genes

C2orf84

Models

Trait associations