Hub : Traits :

Mood swings

476 significantly associated models · 74 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 171053153 172474017 1 1 4.1e-07 9.9e-06 6.9e-05 19 METTL13
2 1 205063949 206329620 1 1 3.8e-07 1.5e-06 5.3e-01 98 SLC41A1
3 3 48381826 51043528 11 2 1.4e-12 1.5e-10 1.2e-01 94 GPX1 RBM6
4 7 11553163 12967449 1 1 1.5e-09 3.3e-09 1.2e-01 93 TMEM106B
5 8 8092025 11860845 11 1 6.8e-10 8.5e-10 1.4e-01 94 AF131215.2
6 8 140969818 142706843 1 1 8.1e-08 7.8e-09 4.1e-04 63 PTK2
7 9 119768572 121177842 1 1 8.1e-09 1.2e-08 1.0e+00 100 TLR4
8 11 46578400 48559571 6 1 2.8e-12 1.1e-11 2.0e-01 96 MADD
9 11 112542418 113969669 2 1 1.8e-09 4.0e-13 2.0e-09 32 ANKK1
10 12 121453962 122915054 1 1 1.3e-07 5.4e-09 1.2e-02 81 TMEM120B
11 14 74531485 76089054 3 1 1.5e-08 1.6e-09 3.5e-02 88 DLST
12 16 86667409 89428967 3 2 1.0e-08 1.4e-08 1.0e+00 100 FBXO31 MVD
13 17 42607368 45796313 23 1 7.2e-17 4.2e-15 9.9e-01 100 LRRC37A4P
14 18 49172179 51753106 1 1 1.5e-07 8.7e-12 3.1e-06 53 DCC
15 18 52209411 54028036 1 1 1.0e-13 1.4e-13 8.0e-02 94 TCF4
16 22 40472399 42633054 7 1 3.0e-11 2.5e-12 2.0e-02 89 SLC25A17

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 2.50 1 0 0.0 0.00 1.0e+00 MADD
Crohns Disease (2017) 1.98 1 1 3.0 0.00 1.0e+00 GPX1
Irritable Bowel Disease (IBD) 2.79 2 1 3.0 0.00 1.0e+00 GPX1 RBM6
Ulcerative Colitis (UC) 2.74 2 1 3.0 0.00 1.0e+00 GPX1 RBM6
Major Depression (MDD) 5.72 3 0 0.0 0.00 1.0e+00 GPX1 TCF4 TMEM106B
Reaction Time 2.04 1 0 0.0 0.00 1.0e+00 FBXO31
Verbal and Numeric Reasoning (VNR) 4.29 6 3 9.1 0.73 1.0e-01 FBXO31 GPX1 LRRC37A4P MADD METTL13 RBM6
Breast Cancer 1.93 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Ovarian Cancer 3.12 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Prostate Cancer 3.27 2 0 0.0 0.00 1.0e+00 GPX1 SLC41A1
Age at First Birth 4.95 2 2 6.1 0.00 1.0e+00 GPX1 RBM6
Body Mass Index (BMI) (2010) 2.63 1 0 0.0 0.00 1.0e+00 MADD
Fasting Glucose 2.53 1 1 3.0 0.00 1.0e+00 MADD
Lupus 1.84 1 0 0.0 0.00 1.0e+00 AF131215.2
Neuroticism 9.79 7 2 6.1 -0.98 1.7e-04 AF131215.2 GPX1 LRRC37A4P MADD SLC25A17 TCF4 TLR4
Primary Biliary Cirrhosis 1.59 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Schizophrenia 2.38 1 0 0.0 0.00 1.0e+00 SLC25A17
Ulcerative Colitis 2.22 1 1 3.0 0.00 1.0e+00 GPX1
Blood Eosinophil Count 1.73 4 3 9.1 0.26 7.4e-01 GPX1 LRRC37A4P RBM6 SLC25A17
Blood Platelet Count 1.81 5 4 12.1 -0.41 4.9e-01 DLST LRRC37A4P MADD METTL13 TMEM120B
Blood Red Count 3.19 3 2 6.1 0.00 1.0e+00 LRRC37A4P METTL13 MVD
Blood White Count 1.36 5 3 9.1 -0.21 7.4e-01 GPX1 LRRC37A4P MADD PTK2 RBM6
Heel T-Score 1.77 6 2 6.1 0.24 6.5e-01 DLST LRRC37A4P MADD RBM6 SLC25A17 TMEM120B
BMI 3.95 6 3 9.1 -0.50 3.1e-01 ANKK1 GPX1 MADD RBM6 TLR4 TMEM120B
Height 1.84 10 10 30.3 0.31 3.8e-01 DCC GPX1 LRRC37A4P MADD METTL13 MVD SLC41A1 TCF4 TMEM106B TMEM120B
Waist Hip Ratio (WHR) 1.89 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P PTK2
Systolic Blood Pressure 2.61 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P MADD
Smoking Status 3.85 4 1 3.0 -0.96 4.4e-02 FBXO31 GPX1 PTK2 TMEM120B
Allergy or Eczema 1.38 1 1 3.0 0.00 1.0e+00 SLC25A17
Hypothyroidism (self reported) 2.25 1 0 0.0 0.00 1.0e+00 PTK2
Respiratory disease 1.95 2 0 0.0 0.00 1.0e+00 MVD RBM6
Type 2 Diabetes (T2D) 1.86 1 0 0.0 0.00 1.0e+00 RBM6
Lung FEV1/FVC ratio 1.37 3 1 3.0 0.00 1.0e+00 DLST LRRC37A4P SLC41A1
Lung FVC 3.81 7 4 12.1 0.65 1.1e-01 DCC GPX1 LRRC37A4P MVD RBM6 SLC41A1 TCF4
Neuroticism 15.30 14 13 39.4 -0.99 5.9e-11 ANKK1 DLST FBXO31 GPX1 LRRC37A4P MADD METTL13 MVD RBM6 SLC25A17 SLC41A1 TCF4 TLR4 TMEM106B
Hair Pigment 0.54 5 3 9.1 -0.06 9.2e-01 FBXO31 LRRC37A4P MVD SLC25A17 SLC41A1
Tanning 0.42 2 0 0.0 0.00 1.0e+00 FBXO31 MVD
Hand grip strength (left) 3.41 4 4 12.1 -0.70 3.0e-01 LRRC37A4P MADD SLC41A1 TCF4
Number of treatments/medications taken 4.77 3 2 6.1 0.00 1.0e+00 DLST GPX1 RBM6
Sensitivity / hurt feelings 8.23 5 2 6.1 0.99 1.8e-03 AF131215.2 ANKK1 FBXO31 LRRC37A4P METTL13
Frequency of depressed mood in last 2 weeks 7.50 5 1 3.0 0.99 1.7e-03 AF131215.2 ANKK1 LRRC37A4P MADD TMEM106B
Hearing difficulty/problems: Yes 2.30 1 1 3.0 0.00 1.0e+00 PTK2
Relative age of first facial hair 4.33 2 1 3.0 0.00 1.0e+00 LRRC37A4P RBM6
Systolic blood pressure, automated reading 2.72 4 3 9.1 0.30 7.0e-01 AF131215.2 GPX1 LRRC37A4P MADD
Medication: Co-codamol 2.43 1 0 0.0 0.00 1.0e+00 RBM6
Pack years adult smoking proportion 2.38 1 0 0.0 0.00 1.0e+00 GPX1
Impedance of leg (right) 3.35 7 6 18.2 0.19 6.8e-01 AF131215.2 GPX1 LRRC37A4P MADD PTK2 RBM6 SLC41A1
Leg fat-free mass (left) 2.49 5 3 9.1 0.09 8.9e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Trunk fat percentage 3.56 8 3 9.1 0.06 8.8e-01 ANKK1 FBXO31 GPX1 LRRC37A4P MADD RBM6 SLC25A17 TMEM120B
Hand grip strength (right) 3.04 4 3 9.1 -0.75 2.5e-01 LRRC37A4P MADD SLC41A1 TCF4
Current tobacco smoking 3.20 1 0 0.0 0.00 1.0e+00 SLC25A17
Fed-up feelings 10.72 9 6 18.2 0.99 1.1e-06 AF131215.2 DCC DLST GPX1 LRRC37A4P MADD MVD RBM6 TLR4
Frequency of unenthusiasm / disinterest in last 2 weeks 6.04 3 0 0.0 0.00 1.0e+00 ANKK1 DCC GPX1
Relative age voice broke 1.99 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Taking other prescription medications 5.87 4 1 3.0 0.99 6.4e-03 DLST GPX1 RBM6 TMEM120B
Age when periods started (menarche) 3.68 3 2 6.1 0.00 1.0e+00 GPX1 MADD SLC41A1
Heel bone mineral density (BMD) T-score, automated (left) 3.40 2 1 3.0 0.00 1.0e+00 AF131215.2 SLC25A17
High blood pressure 3.06 4 2 6.1 -0.51 4.9e-01 AF131215.2 LRRC37A4P MADD PTK2
Multivitamins +/- minerals 1.95 1 0 0.0 0.00 1.0e+00 SLC41A1
Medication: Levothyroxine sodium 2.05 1 0 0.0 0.00 1.0e+00 AF131215.2
Sitting height 2.86 6 5 15.2 -0.36 4.8e-01 DCC FBXO31 LRRC37A4P MADD METTL13 SLC41A1
Body mass index (BMI) 4.90 6 4 12.1 0.38 4.6e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Impedance of leg (left) 3.36 7 5 15.2 0.18 7.0e-01 AF131215.2 GPX1 LRRC37A4P MADD PTK2 RBM6 SLC41A1
Leg predicted mass (left) 2.50 5 3 9.1 0.08 8.9e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Trunk fat mass 3.55 6 3 9.1 0.33 5.3e-01 ANKK1 GPX1 LRRC37A4P MADD RBM6 TMEM120B
Waist circumference 3.12 5 3 9.1 0.52 3.6e-01 ANKK1 GPX1 MADD RBM6 TMEM120B
Number of incorrect matches in round 2.57 1 0 0.0 0.00 1.0e+00 SLC41A1
Nervous feelings 8.02 6 3 9.1 0.95 3.4e-03 AF131215.2 ANKK1 DLST LRRC37A4P MADD SLC25A17
Frequency of tenseness / restlessness in last 2 weeks 7.73 6 1 3.0 0.99 1.4e-04 ANKK1 GPX1 LRRC37A4P MADD RBM6 TMEM106B
Hearing difficulty/problems with background noise 3.48 2 1 3.0 0.00 1.0e+00 LRRC37A4P SLC41A1
Hair/balding pattern: Pattern 2 2.40 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Forced vital capacity (FVC) 3.06 2 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P
Heel bone mineral density (BMD) T-score, automated (right) 3.59 1 1 3.0 0.00 1.0e+00 AF131215.2
Ever unenthusiastic/disinterested for a whole week 4.44 2 0 0.0 0.00 1.0e+00 LRRC37A4P RBM6
Qualifications: None of the above 4.77 4 2 6.1 1.00 3.8e-03 GPX1 PTK2 RBM6 TMEM120B
Financial difficulties in last 2 years 3.25 1 0 0.0 0.00 1.0e+00 TMEM106B
Mouth/teeth dental problems 2.45 1 0 0.0 0.00 1.0e+00 PTK2
Diabetes (self-reported) 1.79 1 0 0.0 0.00 1.0e+00 RBM6
Fluid intelligence score 3.97 6 1 3.0 -0.68 1.4e-01 GPX1 LRRC37A4P MADD METTL13 RBM6 TMEM120B
Neuroticism score 17.06 16 12 36.4 0.98 3.4e-11 AF131215.2 ANKK1 DCC DLST FBXO31 GPX1 LRRC37A4P MADD METTL13 MVD RBM6 SLC25A17 SLC41A1 TCF4 TLR4 TMEM106B
Weight 3.17 7 4 12.1 0.22 6.4e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 SLC41A1 TMEM120B
Impedance of arm (right) 4.51 6 4 12.1 -0.43 3.9e-01 AF131215.2 GPX1 LRRC37A4P RBM6 SLC41A1 TMEM106B
Arm fat percentage (right) 3.98 6 3 9.1 0.31 5.5e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Trunk fat-free mass 1.96 3 2 6.1 0.00 1.0e+00 AF131215.2 RBM6 SLC41A1
Hip circumference 2.93 6 3 9.1 0.43 3.9e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Alcohol intake versus 10 years previously 2.41 1 0 0.0 0.00 1.0e+00 RBM6
Father's age at death 2.40 1 0 0.0 0.00 1.0e+00 GPX1
Worrier / anxious feelings 9.48 7 5 15.2 0.94 1.8e-03 AF131215.2 DLST LRRC37A4P METTL13 SLC25A17 TCF4 TLR4
Frequency of tiredness / lethargy in last 2 weeks 5.16 3 0 0.0 0.00 1.0e+00 DCC GPX1 TMEM106B
Hair/balding pattern: Pattern 3 4.41 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Number of live births 2.09 2 0 0.0 0.00 1.0e+00 LRRC37A4P RBM6
Forced expiratory volume in 1-second (FEV1) 3.63 2 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P
Qualifications: A levels/AS levels or equivalent 5.31 5 2 6.1 -0.94 1.6e-02 GPX1 LRRC37A4P METTL13 RBM6 TMEM120B
Mouth/teeth dental problems: Dentures 2.68 2 0 0.0 0.00 1.0e+00 GPX1 RBM6
Asthma 2.11 2 0 0.0 0.00 1.0e+00 MVD RBM6
Medication: Ibuprofen (e.g. Nurofen) 2.58 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Depression (self-reported) 4.22 1 0 0.0 0.00 1.0e+00 TMEM106B
Forced expiratory volume in 1-second (FEV1), Best measure 3.67 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P MVD
Impedance of arm (left) 4.58 6 4 12.1 -0.47 3.5e-01 AF131215.2 GPX1 LRRC37A4P RBM6 SLC41A1 TMEM106B
Arm fat mass (right) 4.18 6 4 12.1 0.38 4.6e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Trunk predicted mass 1.96 4 2 6.1 -0.12 8.8e-01 AF131215.2 RBM6 SLC41A1 TMEM120B
Standing height 1.96 6 5 15.2 -0.67 1.5e-01 GPX1 LRRC37A4P MADD METTL13 SLC41A1 TMEM106B
Exposure to tobacco smoke at home 2.21 1 0 0.0 0.00 1.0e+00 RBM6
Tense / 'highly strung' 7.53 5 2 6.1 0.99 1.5e-03 AF131215.2 ANKK1 SLC25A17 SLC41A1 TMEM106B
Seen doctor (GP) for nerves, anxiety, tension or depression 6.79 4 2 6.1 0.98 2.3e-02 ANKK1 GPX1 TCF4 TMEM106B
Hair/balding pattern: Pattern 4 5.08 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Birth weight of first child 2.55 1 1 3.0 0.00 1.0e+00 PTK2
Peak expiratory flow (PEF) 3.35 3 2 6.1 0.00 1.0e+00 AF131215.2 LRRC37A4P SLC41A1
Ever highly irritable/argumentative for 2 days 4.26 1 1 3.0 0.00 1.0e+00 RBM6
Qualifications: O levels/GCSEs or equivalent 3.02 1 1 3.0 0.00 1.0e+00 GPX1
Medication: Paracetamol 5.08 3 3 9.1 0.00 1.0e+00 GPX1 LRRC37A4P PTK2
Headache pain in last month 4.34 2 1 3.0 0.00 1.0e+00 LRRC37A4P TLR4
Hypothyroidism/myxoedema (self-reported) 2.45 2 0 0.0 0.00 1.0e+00 AF131215.2 PTK2
Birth weight 2.29 3 1 3.0 0.00 1.0e+00 MADD PTK2 SLC41A1
Chronic bronchitis/emphysema (mother) 2.39 1 0 0.0 0.00 1.0e+00 RBM6
High blood pressure (siblings) 1.95 1 0 0.0 0.00 1.0e+00 TMEM106B
Forced vital capacity (FVC), Best measure 3.18 2 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P
Body fat percentage 3.70 6 3 9.1 0.32 5.4e-01 ANKK1 GPX1 LRRC37A4P MADD RBM6 TMEM120B
Leg fat percentage (right) 4.11 4 3 9.1 0.54 4.6e-01 ANKK1 GPX1 MADD RBM6
Arm fat-free mass (right) 2.53 5 3 9.1 0.17 7.9e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Exposure to tobacco smoke outside home 2.62 1 0 0.0 0.00 1.0e+00 RBM6
Comparative body size at age 10 3.77 3 2 6.1 0.00 1.0e+00 AF131215.2 MADD SLC41A1
Number of full brothers 3.73 1 0 0.0 0.00 1.0e+00 GPX1
Worry too long after embarrassment 4.57 3 1 3.0 0.00 1.0e+00 AF131215.2 ANKK1 LRRC37A4P
Seen a psychiatrist for nerves, anxiety, tension or depression 5.00 1 0 0.0 0.00 1.0e+00 TMEM106B
Wheeze or whistling in the chest in last year 3.93 3 1 3.0 0.00 1.0e+00 GPX1 MVD RBM6
Age at first live birth 5.00 2 2 6.1 0.00 1.0e+00 GPX1 RBM6
Health satisfaction 3.22 1 0 0.0 0.00 1.0e+00 GPX1
Qualifications: College or University degree 6.12 5 4 12.1 -0.94 1.6e-02 FBXO31 GPX1 LRRC37A4P PTK2 RBM6
Medication for pain relief, constipation, heartburn 4.59 4 1 3.0 -1.00 4.5e-03 DLST GPX1 LRRC37A4P PTK2
Neck or shoulder pain in last month 3.00 2 0 0.0 0.00 1.0e+00 GPX1 PTK2
Medication: Ibuprofen 2.49 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Medication: Seretide 50 evohaler 1.74 1 0 0.0 0.00 1.0e+00 RBM6
Mean time to correctly identify matches 2.27 1 0 0.0 0.00 1.0e+00 FBXO31
Whole body fat mass 3.91 5 4 12.1 0.53 3.6e-01 ANKK1 GPX1 MADD RBM6 TMEM120B
Leg fat mass (right) 4.35 6 4 12.1 0.46 3.6e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Arm predicted mass (right) 2.61 5 3 9.1 0.16 8.0e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Alcohol intake frequency. 4.06 5 3 9.1 0.56 3.3e-01 DCC LRRC37A4P MADD RBM6 TCF4
Comparative height size at age 10 2.66 6 4 12.1 -0.69 1.3e-01 DLST GPX1 LRRC37A4P METTL13 SLC41A1 TCF4
Number of full sisters 2.29 1 0 0.0 0.00 1.0e+00 RBM6
Suffer from 'nerves' 7.60 4 3 9.1 0.85 1.5e-01 AF131215.2 ANKK1 DLST MADD
Overall health rating 5.78 4 2 6.1 0.98 2.0e-02 ANKK1 GPX1 RBM6 TMEM120B
Chest pain or discomfort 2.41 1 0 0.0 0.00 1.0e+00 GPX1
Age at last live birth 4.94 2 2 6.1 0.00 1.0e+00 GPX1 RBM6
Knee pain experienced in last month 2.63 1 0 0.0 0.00 1.0e+00 PTK2
Hypertension (Self-reported) 2.82 4 1 3.0 -0.52 4.8e-01 AF131215.2 LRRC37A4P MADD PTK2
Whole body fat-free mass 2.19 5 3 9.1 0.11 8.6e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Leg fat-free mass (right) 2.51 4 3 9.1 -0.13 8.7e-01 AF131215.2 RBM6 SLC41A1 TMEM120B
Arm fat percentage (left) 4.11 6 3 9.1 0.28 5.8e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Average weekly red wine intake 2.35 1 0 0.0 0.00 1.0e+00 RBM6
Handedness (chirality/laterality): Left-handed 2.06 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Loneliness, isolation 7.03 4 2 6.1 0.99 1.3e-02 GPX1 LRRC37A4P MADD TMEM106B
Diabetes diagnosed by doctor 2.09 1 0 0.0 0.00 1.0e+00 RBM6
Mouth/teeth dental problems: Mouth ulcers 2.54 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Back pain experienced in last month 2.63 1 0 0.0 0.00 1.0e+00 PTK2
Asthma (self-reported) 2.17 2 0 0.0 0.00 1.0e+00 MVD RBM6
Osteoarthritis (self-reported) 2.77 1 0 0.0 0.00 1.0e+00 PTK2
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.90 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Whole body water mass 2.23 5 3 9.1 0.12 8.5e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Leg predicted mass (right) 2.49 4 3 9.1 -0.14 8.6e-01 AF131215.2 RBM6 SLC41A1 TMEM120B
Arm fat mass (left) 4.22 6 4 12.1 0.37 4.7e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Number of self-reported non-cancer illnesses 3.84 1 0 0.0 0.00 1.0e+00 TMEM106B
Average weekly champagne plus white wine intake 2.13 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Miserableness 13.14 9 7 21.2 0.98 3.2e-06 AF131215.2 ANKK1 GPX1 LRRC37A4P MADD METTL13 RBM6 TCF4 TMEM106B
Guilty feelings 8.93 7 2 6.1 0.96 4.6e-04 AF131215.2 ANKK1 DLST LRRC37A4P MADD METTL13 RBM6
Financial situation satisfaction 4.51 1 1 3.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 2.44 2 1 3.0 0.00 1.0e+00 AF131215.2 LRRC37A4P
Medication: Bendroflumethiazide 2.70 2 0 0.0 0.00 1.0e+00 AF131215.2 MADD
Medication: Paracetamol 5.09 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A4P PTK2
Illnesses of father: High blood pressure 1.80 1 0 0.0 0.00 1.0e+00 MADD
Basal metabolic rate 2.42 5 3 9.1 0.17 7.9e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Leg fat percentage (left) 4.36 5 3 9.1 0.56 3.2e-01 ANKK1 GPX1 MADD RBM6 TMEM120B
Arm fat-free mass (left) 2.60 5 4 12.1 0.22 7.2e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B
Number of operations (self-reported) 3.33 3 0 0.0 0.00 1.0e+00 GPX1 RBM6 TLR4
Average weekly beer plus cider intake 4.29 2 1 3.0 0.00 1.0e+00 AF131215.2 RBM6
Irritability 9.95 9 4 12.1 0.97 2.4e-05 AF131215.2 ANKK1 GPX1 LRRC37A4P MVD SLC25A17 TCF4 TLR4 TMEM106B
Risk taking 2.10 1 0 0.0 0.00 1.0e+00 AF131215.2
Diastolic blood pressure, automated reading 2.46 4 1 3.0 0.49 5.1e-01 AF131215.2 GPX1 MADD RBM6
Ever depressed for a whole week 3.85 1 0 0.0 0.00 1.0e+00 RBM6
Vascular/heart problems diagnosed by doctor 2.75 3 1 3.0 0.00 1.0e+00 AF131215.2 MADD PTK2
Pain experienced in last month 4.28 4 1 3.0 -1.00 6.5e-05 GPX1 MVD PTK2 RBM6
Pack years of smoking 2.27 1 0 0.0 0.00 1.0e+00 GPX1
Impedance of whole body 4.12 6 5 15.2 -0.20 7.1e-01 AF131215.2 GPX1 LRRC37A4P PTK2 RBM6 SLC41A1
Leg fat mass (left) 4.60 6 5 15.2 0.46 3.6e-01 AF131215.2 ANKK1 GPX1 MADD RBM6 TMEM120B
Arm predicted mass (left) 2.62 5 4 12.1 0.20 7.5e-01 AF131215.2 GPX1 RBM6 SLC41A1 TMEM120B

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 12 0.3437 1.83
GTEx Adipose Visceral Omentum 11 0.5403 1.96
GTEx Adrenal Gland 8 0.5491 1.87
GTEx Artery Aorta 12 0.4031 1.99
GTEx Artery Coronary 10 0.8453 2.13
GTEx Artery Tibial 9 0.2393 1.83
GTEx Brain Caudate basal ganglia 7 0.7609 2.02
GTEx Brain Cerebellar Hemisphere 10 0.6716 1.92
GTEx Brain Cerebellum 14 0.7064 1.88
GTEx Brain Cortex 11 1.0628 2.12
GTEx Brain Frontal Cortex BA9 6 0.6494 2.05
GTEx Brain Hippocampus 4 0.7634 2.12
GTEx Brain Hypothalamus 5 0.8475 2.08
GTEx Brain Nucleus accumbens basal ganglia 7 0.8092 2.01
GTEx Brain Putamen basal ganglia 4 0.6410 2.07
GTEx Breast Mammary Tissue 9 0.4559 1.94
GTEx Breast Mammary Tissue (Male) 7 0.5868 1.95
GTEx Breast Mammary Tissue (Female) 10 0.6083 1.95
GTEx Cells EBV-transformed lymphocytes 12 0.8433 2.13
GTEx Cells Transformed fibroblasts 11 0.2620 1.80
GTEx Colon Sigmoid 10 0.6840 2.03
GTEx Colon Transverse 10 0.4845 1.88
GTEx Esophagus Gastroesophageal Junction 11 0.7612 2.05
GTEx Esophagus Mucosa 16 0.4819 1.87
GTEx Esophagus Muscularis 17 0.5260 1.96
GTEx Heart Atrial Appendage 8 0.5066 1.95
GTEx Heart Left Ventricle 9 0.5882 2.01
GTEx Liver 4 0.5579 2.00
GTEx Lung 14 0.4873 1.91
GTEx Muscle Skeletal 10 0.3460 1.80
GTEx Nerve Tibial 12 0.2777 1.81
GTEx Ovary 7 0.7709 2.17
GTEx Pancreas 9 0.5515 1.94
GTEx Pituitary 6 0.5381 2.00
GTEx Prostate 7 0.8383 2.03
GTEx Skin Not Sun Exposed Suprapubic 13 0.5287 2.04
GTEx Skin Sun Exposed Lower leg 15 0.4121 1.93
GTEx Small Intestine Terminal Ileum 5 1.0846 2.24
GTEx Spleen 9 0.6378 2.01
GTEx Stomach 9 0.6190 1.99
GTEx Testis 12 0.3803 1.92
GTEx Thyroid 16 0.4001 1.83
GTEx Uterus 8 1.4109 2.45
GTEx Vagina 6 0.9449 2.03
GTEx Whole Blood 6 0.3011 1.80
METSIM Adipose 4 0.0868 1.65
NTR Blood 8 0.3331 1.73
ROSMAP Brain Pre-frontal Cortex 5 0.1139 1.73
YFS Blood 7 0.1516 1.60
CommonMind Brain Pre-frontal Cortex 6 0.1116 1.74
TCGA Breast Tumor 3 0.3911 1.82
TCGA Breast Normal 4 0.0951 1.53
TCGA Ovarian Tumor 6 0.2053 1.76
TCGA Prostate Tumor 5 0.1446 1.65