TWAS hub - MDM1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1420	0.0350	4.8e-07	0.108	0.074	0.092	0.104	0.106	4.9e-13	2.5e-09	2.9e-11	1.4e-12	6.9e-13
2	GTEx	Adipose Subcutaneous	0.1260	0.0460	1.5e-03	0.143	NA	0.108	NA	0.137	1.0e-11	NA	3.8e-09	NA	2.6e-11
3	GTEx	Adipose Visceral Omentum	0.2210	0.0750	1.3e-03	0.062	NA	0.071	NA	0.068	3.7e-04	NA	1.5e-04	NA	2.0e-04
4	GTEx	Brain Hippocampus	0.3932	0.1099	5.1e-03	-0.012	NA	-0.011	NA	-0.008	8.5e-01	NA	7.0e-01	NA	5.3e-01
5	GTEx	Cells Transformed fibroblasts	0.1950	0.0470	7.5e-06	0.205	NA	0.184	NA	0.196	2.7e-15	NA	8.6e-14	NA	1.2e-14
6	GTEx	Esophagus Mucosa	0.1960	0.0540	8.6e-05	0.026	NA	0.039	NA	0.037	6.8e-03	NA	1.3e-03	NA	1.6e-03
7	GTEx	Esophagus Muscularis	0.2510	0.0640	1.1e-04	0.129	NA	0.120	NA	0.115	3.0e-08	NA	1.0e-07	NA	1.9e-07
8	GTEx	Nerve Tibial	0.2255	0.0527	1.4e-06	0.197	NA	0.183	NA	0.193	6.3e-14	NA	5.4e-13	NA	1.1e-13
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1550	0.0520	1.6e-03	0.119	NA	0.132	NA	0.153	4.8e-07	NA	1.0e-07	NA	9.1e-09
10	GTEx	Thyroid	0.2080	0.0460	1.4e-06	0.145	NA	0.143	NA	0.152	3.3e-11	NA	4.3e-11	NA	1.1e-11
11	GTEx	Whole Blood	0.1330	0.0440	5.9e-05	0.008	NA	0.000	NA	0.011	6.0e-02	NA	3.5e-01	NA	3.3e-02
12	METSIM	Adipose	0.0488	0.0185	2.5e-03	0.012	0.012	0.005	0.013	0.006	4.9e-03	5.5e-03	5.5e-02	4.1e-03	4.2e-02
13	YFS	Blood	0.0224	0.0096	4.6e-03	0.000	0.004	-0.001	0.004	-0.001	2.5e-01	1.7e-02	9.9e-01	1.5e-02	9.6e-01
14	TCGA	Breast Invasive Carcinoma	0.0349	0.0173	2.4e-04	0.006	0.015	0.014	NA	0.005	1.6e-02	3.6e-04	5.3e-04	NA	2.7e-02
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0655	0.0270	6.9e-05	0.041	0.025	0.046	NA	0.042	1.7e-05	7.9e-04	6.3e-06	NA	1.3e-05
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1000	0.0460	4.0e-03	0.028	0.032	0.011	NA	0.025	9.4e-03	6.3e-03	7.7e-02	NA	1.4e-02
17	TCGA	Pancreatic Adenocarcinoma	0.1190	0.0700	9.1e-03	0.044	0.040	0.008	NA	0.042	6.1e-03	8.3e-03	1.5e-01	NA	7.2e-03
18	TCGA	Prostate Adenocarcinoma	0.0384	0.0194	3.9e-03	0.054	0.015	0.035	NA	0.050	2.5e-06	8.4e-03	1.3e-04	NA	5.1e-06
19	TCGA	Thyroid Carcinoma	0.1730	0.0440	3.8e-15	0.196	0.162	0.195	NA	0.200	9.1e-19	1.6e-15	9.9e-19	NA	3.7e-19

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Frequency of tenseness / restlessness in last 2 weeks	4.6	7.1	14.6	3.3	3.6	2.3	1.0	3.4	1.8	3.1	3.4	0.1	3.4	-0.0	1.7	-0.1	1.3	2.7	3.8	2.9	3.3	3.2
Hand grip strength (right)	4.2	11.5	18.1	-4.0	-4.2	-3.1	-1.6	-4.0	-4.1	-3.5	-4.1	-1.1	-4.1	1.6	-1.5	0.0	-2.3	-3.8	-4.3	-4.0	-4.0	-4.1
Hand grip strength (left)	4.1	10.8	20.2	-3.8	-4.0	-3.2	-2.2	-3.8	-4.2	-3.4	-3.8	-1.3	-3.9	0.8	-1.8	-0.4	-1.3	-3.8	-4.5	-3.7	-3.8	-4.0
Medication: Ibuprofen	4.1	4.9	8.4	-2.7	-2.7	-1.6	-2.0	-2.6	-2.9	-2.5	-2.6	-0.7	-2.6	-0.2	-1.3	1.7	-1.0	-2.9	-2.0	-2.4	-2.7	-2.6
Irritability	4.1	6.9	11.7	3.4	3.4	2.0	0.7	3.3	2.6	2.9	3.2	0.4	3.1	-0.8	0.8	0.3	2.1	3.3	3.1	3.0	3.4	3.3
Basal cell carcinoma (self-reported)	4.1	4.8	10.5	2.4	2.3	2.2	1.3	2.3	3.2	2.6	2.1	2.8	2.0	-1.3	0.6	-1.3	2.3	2.3	2.2	2.3	2.4	2.4
Osteoarthritis (self-reported)	3.9	5.1	9.2	2.8	2.8	0.7	1.3	2.7	2.6	2.4	2.7	-0.2	3.0	-0.2	1.6	0.4	1.5	3.0	2.3	2.6	2.8	2.9
Ever had stillbirth, spontaneous miscarriage or termination	3.7	4.0	8.8	-2.2	-2.4	-3.0	0.4	-2.2	-1.5	-1.6	-2.1	-2.4	-2.2	-0.1	-1.8	-0.3	-2.3	-1.9	-1.2	-2.8	-2.2	-2.1
Triglycerides	3.4	5.5	10.6	-2.8	-2.7	-1.2	-1.8	-2.9	-2.4	-3.1	-3.1	0.5	-3.3	0.8	-1.9	-1.0	-1.6	-2.4	-1.8	-3.0	-2.8	-2.7
Neuroticism score	3.2	6.7	11.8	3.1	3.4	2.1	2.3	3.1	2.4	2.6	3.1	0.4	3.0	0.9	2.4	1.3	1.7	2.7	2.8	3.4	3.1	3.0
Other serious medical condition/disability diagnosed by doctor	3.1	4.0	9.3	2.3	2.3	2.6	0.7	2.2	2.5	2.4	2.2	1.2	2.2	-1.0	0.5	-0.7	0.8	1.9	3.1	1.8	2.3	2.3
Bilateral oophorectomy (both ovaries removed)	3.0	3.4	8.8	-2.0	-2.0	-3.0	-1.7	-2.1	-2.6	-1.5	-2.0	-1.9	-2.0	-1.3	-1.0	-0.3	0.1	-1.9	-1.4	-2.0	-2.0	-1.9
Frequency of tiredness / lethargy in last 2 weeks	2.8	4.5	9.8	2.5	2.6	1.7	1.5	2.5	2.2	2.3	2.4	-0.9	2.5	-0.2	2.3	-0.8	0.1	2.4	3.1	1.8	2.5	2.6
Medication: Co-codamol	2.6	3.0	5.2	-2.0	-1.9	-2.1	-1.1	-1.9	-1.6	-1.7	-1.8	-0.7	-1.8	-1.4	-2.0	-2.3	0.2	-2.0	-1.2	-1.7	-2.0	-1.9
Taking other prescription medications	2.4	3.7	10.2	2.0	2.5	1.9	1.3	2.2	1.9	3.2	2.3	1.0	2.2	-1.6	0.5	-0.6	1.3	1.2	2.3	2.0	2.1	1.9
Prospective memory result	2.4	3.0	7.7	1.9	2.1	1.6	1.7	2.0	2.5	1.7	2.1	-0.2	1.8	-0.3	0.8	-0.6	0.1	2.0	2.8	1.3	1.9	2.1
Tense / ‘highly strung’	2.4	4.0	6.9	2.2	2.6	2.2	2.1	2.3	2.0	2.2	2.3	0.8	2.2	-0.4	1.4	-0.2	1.8	1.9	2.5	2.2	2.2	2.1
Medication: Lansoprazole	2.3	2.6	8.3	1.7	1.6	0.6	1.5	1.6	2.2	1.6	1.8	-0.5	1.7	0.0	1.3	-2.9	-0.6	1.8	2.0	0.8	1.7	1.7
Blood clot in the leg (DVT)	2.3	3.0	8.6	-2.1	-1.9	-1.3	-0.8	-1.8	-2.2	-0.4	-1.8	0.0	-1.8	0.5	-0.9	-0.4	-1.5	-2.9	-2.7	-1.6	-2.1	-2.3
Guilty feelings	2.3	3.4	6.3	2.0	2.3	2.2	1.4	2.2	2.0	2.2	2.2	1.4	1.9	0.6	1.6	0.0	1.1	1.6	2.2	2.5	2.0	2.0
Nervous feelings	2.2	4.1	8.2	2.2	2.6	1.6	2.8	2.3	2.2	2.9	2.2	0.3	2.1	-1.1	0.7	-0.0	1.9	1.6	2.1	2.6	2.2	2.0
Hair/balding pattern: Pattern 3	2.2	3.3	7.5	2.0	2.2	2.7	-0.4	2.3	1.1	2.6	2.0	-0.1	1.9	2.0	-0.5	1.4	-1.2	1.3	1.7	2.3	2.0	2.0
Vitamin and mineral supplements	2.1	2.9	7.6	2.0	1.8	0.9	1.4	1.7	2.5	1.0	1.8	1.3	1.5	-0.5	0.2	0.2	1.9	2.8	1.4	2.2	2.0	2.3
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	4.9	2.1	1.9	1.7	-0.1	1.9	1.5	1.3	2.0	1.1	1.9	-0.2	1.1	0.0	0.7	2.2	1.2	1.8	2.1	2.1
Depression (self-reported)	2.1	2.6	4.9	1.7	2.0	1.4	1.9	1.8	1.5	1.6	1.9	-0.7	1.6	0.5	2.2	1.2	0.2	1.7	1.8	1.6	1.7	1.8
Worry too long after embarrassment	2.1	3.6	8.6	2.2	2.5	1.8	1.2	2.3	1.3	1.9	2.2	1.3	2.4	1.6	1.5	1.7	0.7	1.7	0.6	2.9	2.2	2.1
Medication: Seretide 50 evohaler	2.1	2.4	8.3	1.6	1.7	1.1	0.8	1.7	1.6	2.4	1.5	-0.5	1.3	-1.7	-0.1	-1.2	0.7	1.6	2.9	1.1	1.6	1.7
Supplements: Vitamin C	2.1	2.5	4.1	-1.9	-1.9	-0.9	-0.1	-1.9	-1.5	-1.9	-1.8	-0.1	-1.6	1.1	1.3	-0.3	-1.3	-1.9	-2.0	-1.8	-1.9	-2.0
Number of self-reported non-cancer illnesses	2.1	3.6	8.3	2.0	2.5	2.0	2.2	2.3	2.2	2.9	2.3	0.0	2.5	-0.3	0.2	0.6	0.9	1.2	2.2	2.3	2.0	1.9
Supplements: Fish oil (including cod liver oil)	2.1	2.8	5.1	-2.0	-2.3	-1.3	-1.2	-2.0	-1.4	-2.2	-1.9	0.5	-1.7	0.5	-0.9	-0.3	-1.9	-1.5	-1.9	-1.9	-2.0	-1.9
Frequency of depressed mood in last 2 weeks	2.0	2.8	9.1	1.8	2.0	0.8	2.1	1.7	1.7	1.9	2.0	-0.8	2.0	-0.4	1.2	-0.3	0.8	1.9	3.0	1.3	1.8	1.8
Allergy or Eczema	1.9	5.1	10.0	-2.4	-2.1	-3.0	-1.3	-2.2	-3.2	-2.5	-2.1	-3.2	-2.2	0.9	-1.1	1.3	-2.4	-2.4	-1.8	-2.4	-2.4	-2.3
Hearing difficulty/problems with background noise	1.9	3.1	6.9	2.1	2.0	1.4	-0.0	2.2	1.7	2.0	2.4	-0.8	2.2	-0.4	1.2	-0.2	0.6	1.8	2.6	1.8	2.1	2.1
Asthma	1.9	3.7	7.3	2.4	2.7	0.7	-0.2	2.5	1.3	1.9	2.2	0.3	2.3	-2.4	0.2	-0.9	1.7	2.1	2.3	2.0	2.4	2.4
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	5.3	-1.8	-1.8	-0.9	-1.9	-1.7	-2.3	-1.7	-1.8	-0.8	-1.8	-0.4	-1.2	1.3	-0.5	-2.0	-1.1	-1.7	-1.8	-1.8
Asthma (self-reported)	1.9	3.7	7.4	2.4	2.7	0.7	0.2	2.5	1.4	2.1	2.2	0.1	2.3	-2.4	0.2	-1.0	1.8	2.1	2.5	1.9	2.4	2.3
Diabetes (father)	1.8	2.3	8.8	-1.3	-1.2	-3.0	-0.9	-1.2	-2.0	-0.9	-1.1	-2.5	-0.7	1.5	-1.0	0.3	-1.8	-1.5	-1.8	-1.1	-1.3	-1.3
Exposure to tobacco smoke outside home	1.8	2.4	4.2	1.8	2.1	1.6	1.5	1.9	1.8	1.6	1.7	1.4	1.9	0.2	-0.3	-0.8	0.7	1.5	1.3	1.9	1.8	1.8
Suffer from ‘nerves’	1.8	2.9	5.9	2.0	2.3	1.7	1.0	2.2	1.1	2.4	2.1	0.5	2.0	-0.7	0.1	0.4	1.5	1.4	1.9	2.2	2.0	1.8
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	7.5	-1.8	-1.6	-1.0	-0.8	-1.5	-2.0	-0.1	-1.5	0.2	-1.6	0.2	-1.0	-0.6	-1.2	-2.7	-2.3	-1.5	-1.8	-2.0
Supplements: Glucosamine	1.7	2.2	4.9	-1.7	-1.6	-1.2	-1.8	-1.6	-2.2	-1.6	-1.7	-0.4	-1.4	0.4	0.0	1.1	-1.1	-1.9	-1.8	-1.6	-1.7	-1.8
Loneliness, isolation	1.7	2.3	6.6	1.7	1.8	1.5	1.1	1.7	1.6	1.2	1.8	0.5	1.4	-0.2	0.1	1.3	1.4	1.9	2.6	1.6	1.7	1.9
Heart disease (siblings)	1.7	2.1	11.2	0.4	0.3	-0.1	-2.7	0.4	-0.4	0.3	0.3	2.2	0.3	-3.3	-2.5	-1.8	2.2	0.3	1.1	0.1	0.4	0.4
Neuroticism (2016)	1.6	2.4	4.5	1.8	2.1	1.4	0.3	1.9	1.5	1.6	1.6	0.8	2.1	-1.2	0.1	0.0	1.5	1.5	1.9	1.8	1.8	1.8
Type 2 Diabetes (T2D) (2018)	1.6	2.9	6.0	2.0	2.2	1.8	0.9	2.1	1.5	2.1	2.3	0.8	2.5	-0.6	1.0	-0.4	0.7	1.6	1.9	1.9	2.0	1.9
Pulse wave reflection index	1.6	2.0	3.5	-1.7	-1.6	-0.8	-1.5	-1.6	-1.8	-1.1	-1.5	0.9	-1.9	-0.0	-0.8	-0.8	-1.4	-1.8	-1.1	-1.9	-1.7	-1.7
Glaucoma (self-reported)	1.6	1.9	4.6	1.5	1.7	0.8	0.8	1.7	0.8	2.1	1.9	-0.3	2.1	0.8	0.7	1.6	-0.0	0.7	1.5	1.8	1.5	1.3
Mineral and other dietary supplements	1.6	2.2	3.9	1.8	1.8	0.8	1.8	1.7	1.7	2.0	1.7	-0.0	1.4	-0.5	0.3	0.2	1.6	1.8	0.9	1.8	1.8	1.8
Miserableness	1.6	2.7	4.9	1.8	2.2	0.6	2.0	2.0	1.1	2.2	2.2	-0.5	2.0	0.4	2.1	0.7	0.6	1.3	1.9	1.9	1.8	1.7
Commuting to job workplace: Public transport	1.6	1.9	5.1	1.4	1.4	2.0	0.3	1.6	1.4	2.3	1.7	-0.0	1.6	0.8	0.3	1.2	-0.3	0.8	1.7	1.8	1.4	1.4
HDL Cholesterol	1.5	2.5	4.9	1.8	1.9	1.5	0.6	2.0	1.5	2.2	2.0	1.0	1.8	-0.8	0.2	0.5	1.6	1.5	1.0	2.2	1.8	1.8
Number of treatments/medications taken	1.5	2.6	6.6	1.9	2.2	1.8	0.3	2.1	1.0	2.6	2.3	-0.4	2.0	1.3	1.4	0.3	-0.6	0.8	1.8	1.7	1.9	1.6
Severe depression (siblings)	1.5	1.6	4.9	1.4	1.3	0.8	0.9	1.4	1.4	1.3	1.4	-0.4	1.4	-0.5	1.0	-1.5	-0.0	1.4	2.2	1.1	1.4	1.5
Arm predicted mass (right)	1.5	7.5	14.9	-3.3	-3.4	-2.6	-1.5	-3.3	-2.8	-2.9	-3.1	0.1	-3.3	1.3	-1.8	0.7	-1.9	-3.0	-3.9	-3.2	-3.3	-3.2
Medication: Atorvastatin	1.5	1.9	3.6	1.8	1.8	0.7	0.6	1.6	1.3	1.2	1.7	-0.9	1.9	-0.4	0.2	0.2	1.2	1.9	1.4	1.5	1.8	1.8
Bipolar Disorder (2011)	1.4	1.4	4.6	1.1	0.9	1.8	-1.1	1.0	0.6	0.3	1.2	1.9	1.1	-0.6	-0.8	0.8	2.1	1.1	0.5	1.2	1.1	1.0
Ulcerative Colitis	1.4	2.0	19.9	-1.0	-1.1	-0.0	-0.4	-1.0	-0.1	-1.4	-0.9	0.5	-1.1	-2.1	0.8	-4.5	0.6	-0.9	0.5	-1.1	-1.0	-0.9
Average weekly spirits intake	1.4	1.8	7.0	1.1	1.4	0.3	-0.2	1.3	0.4	1.8	1.1	1.2	1.2	-2.6	-0.5	-2.3	1.9	0.6	1.2	0.8	1.1	0.9
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.4	-1.3	-1.2	-2.1	-1.0	-1.2	-2.0	-1.6	-1.2	-1.7	-1.3	0.2	-0.0	-0.1	-0.9	-1.3	-1.1	-1.4	-1.3	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.7	3.8	1.6	1.6	0.6	-0.0	1.6	0.6	1.5	1.8	-0.5	1.7	0.6	0.9	2.0	0.1	1.2	0.5	1.8	1.6	1.4
Exposure to tobacco smoke at home	1.4	1.5	2.8	1.5	1.5	1.0	0.4	1.5	0.9	1.1	1.3	-0.8	1.0	1.7	0.9	0.2	-1.5	1.6	1.3	1.0	1.5	1.5
Medication: Blood pressure	1.4	2.5	4.5	1.9	1.9	1.5	0.7	1.9	2.0	1.9	2.0	0.3	2.1	-0.3	-0.3	0.4	-0.1	1.6	2.0	1.6	1.9	1.8
Ulcerative Colitis (UC)	1.3	2.4	29.9	-0.6	-0.4	0.9	-0.1	-0.5	0.3	-0.4	-0.5	0.8	-0.6	-2.5	1.1	-5.5	0.8	-0.8	1.3	-0.7	-0.6	-0.6
Coronary Artery Disease (CAD)	1.3	1.6	3.0	1.6	1.6	1.6	-1.3	1.6	-0.2	1.3	1.7	-0.0	1.7	0.2	-0.0	1.7	0.4	0.8	1.1	1.4	1.6	1.3
High blood pressure (mother)	1.3	1.9	4.6	1.1	1.3	1.7	-0.2	1.4	0.4	2.1	1.6	0.6	1.6	-2.1	-0.7	-1.5	1.7	-0.0	2.2	1.1	1.1	0.8
Impedance of leg (left)	1.3	6.5	11.2	3.2	3.2	2.2	-0.4	3.1	2.2	1.8	2.9	0.0	3.2	-0.6	1.9	1.5	1.7	3.3	3.1	3.3	3.2	3.3
Pulse wave Arterial Stiffness index	1.3	1.5	2.7	-1.5	-1.5	-1.1	-1.1	-1.4	-1.2	-0.9	-1.2	-0.1	-1.4	0.3	-0.6	-1.3	-1.0	-1.6	-0.9	-1.6	-1.4	-1.4
Leg fat-free mass (right)	1.3	6.9	11.6	-3.3	-3.4	-2.4	-0.5	-3.3	-2.3	-2.2	-3.0	0.1	-3.3	0.3	-2.3	-0.2	-1.4	-3.1	-3.4	-3.4	-3.3	-3.3
Leg predicted mass (right)	1.3	7.0	11.8	-3.3	-3.4	-2.4	-0.6	-3.3	-2.3	-2.3	-3.0	0.2	-3.3	0.2	-2.3	-0.2	-1.4	-3.1	-3.4	-3.4	-3.3	-3.3
Supplements: Calcium	1.3	1.5	3.9	-1.2	-1.3	-0.9	-2.0	-1.2	-1.7	-1.5	-1.3	-0.5	-1.2	0.7	-1.1	0.9	-0.8	-1.2	-0.7	-1.2	-1.2	-1.2
Impedance of whole body	1.3	6.7	11.1	3.3	3.2	2.0	0.4	3.1	2.5	2.3	3.0	-0.2	3.0	-1.2	1.5	1.3	2.0	3.3	3.2	3.1	3.3	3.3
Lupus	1.2	1.8	4.4	1.6	1.4	0.5	1.5	1.3	1.6	1.7	1.5	-0.6	1.1	0.3	1.1	2.1	0.7	1.5	1.3	1.5	1.5	1.6
Leg fat-free mass (left)	1.2	6.3	11.1	-3.1	-3.2	-2.2	-0.5	-3.1	-2.1	-2.1	-2.8	-0.1	-3.2	0.7	-1.9	-0.3	-1.8	-3.0	-3.1	-3.3	-3.1	-3.1
Medication: Levothyroxine sodium	1.2	2.0	5.6	1.4	1.4	2.1	1.9	1.3	2.4	1.0	1.4	0.9	0.9	-0.1	0.9	1.1	0.7	1.7	1.3	1.4	1.4	1.5
Leg predicted mass (left)	1.2	6.3	11.1	-3.1	-3.2	-2.2	-0.5	-3.1	-2.1	-2.1	-2.8	-0.1	-3.2	0.6	-1.8	-0.4	-1.8	-3.0	-3.1	-3.3	-3.1	-3.1
Illnesses of siblings	1.2	1.7	10.3	-0.4	-0.6	-0.1	2.0	-0.5	0.1	-0.8	-0.4	-1.4	-0.0	3.2	1.7	2.2	-2.0	0.1	-1.3	0.0	-0.4	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	3.5	-1.6	-1.3	-1.5	-0.9	-1.3	-1.9	-1.1	-1.4	-0.9	-1.5	1.1	-1.0	1.5	-0.8	-1.7	-1.7	-1.1	-1.6	-1.6
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.0	1.6	1.7	1.3	0.1	1.7	1.0	1.3	1.5	0.2	1.6	0.1	1.2	0.1	0.3	1.2	0.9	1.7	1.6	1.5
Arm fat-free mass (right)	1.2	6.4	14.3	-3.0	-3.1	-2.4	-1.4	-3.0	-2.5	-2.5	-2.8	0.4	-3.0	1.4	-1.8	0.7	-1.8	-2.7	-3.8	-2.8	-3.0	-2.9
Alcohol intake frequency.	1.2	2.7	5.2	1.7	2.0	2.3	1.5	1.9	2.1	1.5	1.9	-0.3	2.0	1.3	1.3	0.8	-0.7	1.5	2.2	1.6	1.7	1.8
Age started oral contraceptive pill	1.2	1.5	3.0	1.3	1.4	1.4	1.5	1.4	1.2	1.5	1.4	0.3	1.4	1.1	1.4	0.8	-0.6	0.8	0.4	1.7	1.3	1.2
Worry (Nagel 2018)	1.1	2.3	4.5	1.6	2.1	1.5	2.0	1.8	1.1	2.1	1.7	-0.4	1.6	1.0	1.8	1.0	0.5	0.9	1.5	2.0	1.6	1.4
Irritable Bowel Disease (IBD)	1.1	2.7	28.8	-1.1	-0.8	0.2	0.6	-1.0	0.5	-0.3	-1.1	0.1	-0.9	-3.1	0.5	-5.4	0.8	-1.1	1.5	-1.1	-1.1	-1.0
Blood Eosinophil Count	1.1	8.1	16.4	3.0	3.0	4.0	2.7	3.0	4.0	2.1	3.0	2.2	2.9	2.8	2.9	1.7	1.4	3.0	1.2	3.5	3.0	3.0
Blood Platelet Count	1.1	12.2	19.2	4.4	4.3	3.1	2.7	4.3	4.0	3.3	4.3	0.8	4.0	0.6	1.8	1.3	2.1	4.3	3.5	4.3	4.4	4.4
Respiratory disease	1.1	2.4	5.6	2.0	2.4	0.7	0.0	2.2	1.1	1.9	2.0	0.6	1.9	-0.8	0.7	0.6	1.2	1.6	1.2	1.9	2.0	2.0
Neuroticism	1.1	2.7	5.6	1.8	2.2	0.9	2.0	1.9	1.5	1.7	1.8	0.7	1.6	0.6	2.1	-0.0	1.6	1.5	1.6	2.4	1.8	1.7
Angina	1.1	1.4	2.4	1.4	1.4	1.0	-0.7	1.4	0.6	0.9	1.4	1.2	1.5	-0.8	0.0	0.6	1.3	1.3	1.2	1.5	1.4	1.4
Impedance of leg (right)	1.1	5.5	9.1	2.9	2.9	2.3	-0.3	2.8	2.0	1.7	2.7	-0.4	2.8	0.1	2.4	1.1	0.9	3.0	3.0	2.9	2.9	3.0
Chronic bronchitis/emphysema (father)	1.1	1.2	7.7	0.1	0.1	1.8	-0.4	0.1	0.8	0.6	0.1	2.8	-0.3	-2.3	-1.0	-0.4	2.3	-0.0	0.3	0.1	0.1	0.1
Impedance of arm (right)	1.1	5.0	9.4	2.7	2.7	1.9	1.6	2.6	2.6	2.7	2.5	-0.8	2.5	-1.5	1.5	0.1	1.2	2.4	3.1	2.2	2.7	2.6
Birth weight	1.1	2.4	5.0	-1.9	-2.0	-1.4	-0.7	-2.0	-1.5	-2.2	-1.8	0.4	-1.6	-0.6	-1.7	0.1	0.4	-1.5	-1.3	-2.2	-1.9	-1.8
Whole body fat-free mass	1.1	6.0	11.5	-3.0	-3.1	-2.3	-0.9	-3.0	-2.3	-2.2	-2.8	0.2	-3.0	0.8	-1.8	-0.0	-1.6	-2.8	-3.4	-3.0	-3.0	-3.0
Average weekly red wine intake	1.1	1.7	5.7	-1.2	-1.4	-0.9	-2.4	-1.1	-2.3	-1.2	-1.1	-1.0	-1.3	-0.1	-1.0	-0.1	-0.2	-1.4	-1.7	-1.2	-1.2	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.6	0.9	1.1	1.4	1.9	1.0	1.9	1.7	1.1	0.6	1.1	0.6	0.6	-0.8	0.3	0.7	0.9	1.3	0.9	0.9
Whole body water mass	1.1	6.4	12.2	-3.1	-3.2	-2.3	-0.9	-3.1	-2.4	-2.4	-2.9	0.1	-3.1	1.0	-1.7	0.0	-1.8	-2.9	-3.5	-3.1	-3.1	-3.1
Arm fat-free mass (left)	1.1	5.7	12.6	-2.9	-3.0	-2.1	-0.8	-2.9	-2.2	-2.4	-2.7	0.5	-2.9	1.2	-1.4	0.4	-1.5	-2.6	-3.5	-2.7	-2.9	-2.9
Neuroticism (Nagel 2018)	1.0	2.2	4.8	1.6	2.2	1.3	0.9	1.8	0.6	1.7	1.9	0.0	1.7	1.1	2.1	1.4	0.7	0.9	1.3	2.1	1.6	1.4
Ovarian Cancer	1.0	1.3	2.4	-1.3	-1.4	-0.8	0.1	-1.4	-0.8	-1.4	-1.3	-0.5	-0.9	1.6	0.8	0.4	-0.6	-1.3	-1.5	-1.1	-1.3	-1.3
Age at First Birth	1.0	1.4	4.2	1.2	1.2	2.1	0.3	1.2	0.9	1.4	1.1	1.2	1.3	-0.3	-0.1	1.7	1.2	0.9	1.1	1.5	1.2	1.1
Blood Red Count	1.0	10.1	14.9	-3.7	-3.5	-3.7	-1.1	-3.5	-2.9	-2.9	-3.5	-3.4	-3.8	1.4	-1.0	-1.7	-3.9	-3.7	-3.3	-3.6	-3.6	-3.6
Systolic Blood Pressure	1.0	4.8	9.5	2.8	2.6	1.5	0.0	2.7	2.2	2.2	2.9	-0.3	2.7	-1.4	-1.1	-0.4	1.8	2.6	3.1	2.1	2.8	2.7
Hayfever, allergic rhinitis or eczema	1.0	2.2	7.6	-1.5	-1.1	-2.3	-0.8	-1.2	-2.2	-1.0	-1.2	-2.8	-1.2	-0.3	-1.4	0.5	-1.3	-1.7	-0.9	-1.7	-1.5	-1.5
Trunk fat-free mass	1.0	5.7	11.2	-2.9	-3.0	-2.3	-1.1	-2.9	-2.4	-2.2	-2.8	0.2	-2.8	0.7	-1.7	-0.2	-1.5	-2.7	-3.3	-2.9	-2.9	-2.9
Impedance of arm (left)	1.0	4.6	8.4	2.7	2.6	1.7	0.9	2.6	2.3	2.4	2.5	-0.8	2.4	-1.3	1.3	0.5	1.3	2.5	2.9	2.3	2.7	2.6
Trunk predicted mass	1.0	5.7	11.5	-2.9	-2.9	-2.3	-1.1	-2.9	-2.4	-2.2	-2.8	0.1	-2.8	0.8	-1.6	-0.1	-1.6	-2.7	-3.4	-2.8	-2.9	-2.9
Peak expiratory flow (PEF)	1.0	2.4	7.0	-1.7	-1.9	-1.6	-0.2	-1.8	-1.2	-1.3	-1.9	-0.5	-2.0	-0.3	-1.9	-0.6	0.0	-1.3	-2.6	-1.5	-1.7	-1.8
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.9	-1.5	-1.7	-0.4	-0.8	-1.5	-0.9	-1.4	-1.5	0.9	-1.7	-0.3	-0.9	-0.8	-0.4	-1.5	-1.1	-1.6	-1.5	-1.6
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.0	-1.5	-1.6	-1.4	0.1	-1.6	-1.2	-1.3	-1.7	-0.2	-1.6	-0.2	-0.0	-1.0	0.5	-1.2	-1.5	-1.4	-1.5	-1.5
Wheeze or whistling in the chest in last year	1.0	1.7	4.1	1.3	1.7	0.6	1.3	1.4	1.4	1.2	1.6	-1.4	1.0	0.4	1.5	0.1	-1.3	1.2	2.0	1.0	1.3	1.5
Leg pain on walking	1.0	1.3	12.9	1.0	1.1	0.4	0.1	0.9	0.2	0.5	1.0	-0.5	1.1	0.7	3.6	0.2	-0.7	0.8	1.1	0.8	1.0	1.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.1	-1.0	-1.3	-2.3	-0.8	-1.2	-0.6	-1.5	-1.5	-0.7	-1.1	-0.2	-0.5	-1.3	0.3	-0.3	-1.6	-1.1	-1.0	-0.8
Basal metabolic rate	1.0	5.7	10.9	-3.0	-3.0	-2.1	-0.8	-3.0	-2.1	-2.1	-2.7	0.4	-3.0	0.9	-1.8	0.1	-1.6	-2.8	-3.3	-2.9	-3.0	-2.9
Unable to work because of sickness or disability	1.0	1.3	2.8	1.4	1.6	0.1	-0.1	1.4	0.3	1.5	1.7	-1.5	1.1	-1.1	-0.2	-0.8	0.9	1.0	1.2	0.9	1.4	1.2
Major Depression (MDD)	0.9	1.1	2.7	1.0	1.0	-0.1	0.9	1.1	0.2	1.5	0.9	-1.6	1.1	1.5	1.0	1.3	-1.6	0.4	0.3	0.7	1.0	0.9
Crohns Disease (2012)	0.9	1.4	2.8	-1.6	-1.5	-1.0	0.6	-1.6	-0.2	-0.8	-1.7	0.1	-1.5	-1.2	-0.6	-1.5	0.2	-1.5	-0.1	-1.2	-1.6	-1.5
Medication: Metformin	0.9	1.3	3.1	1.2	1.4	1.4	-0.4	1.4	0.4	1.4	1.4	1.0	1.7	-0.8	-0.5	-0.1	0.8	0.5	1.8	1.1	1.2	1.1
Multivitamins +/- minerals	0.9	1.1	4.4	-1.1	-0.9	-0.5	-1.2	-0.8	-1.6	-0.1	-0.8	-0.8	-0.8	0.5	-0.1	-0.7	-2.1	-1.7	-0.7	-1.3	-1.1	-1.2
Medication: Simvastatin	0.9	1.4	4.5	1.0	1.1	2.1	-0.5	1.1	0.5	0.4	1.2	1.1	1.2	1.2	1.6	1.9	-0.2	0.8	1.2	1.2	1.0	1.0
Forced vital capacity (FVC), Best measure	0.9	3.3	6.1	-2.2	-2.3	-2.0	-0.4	-2.2	-1.9	-1.9	-2.2	-0.2	-2.2	0.2	-2.2	0.1	-0.3	-1.9	-2.5	-1.8	-2.2	-2.2
Comparative body size at age 10	0.9	2.4	4.8	-1.8	-1.6	-1.6	-1.4	-1.7	-2.2	-1.8	-1.4	-0.1	-1.5	0.9	-0.2	0.6	-1.3	-1.9	-2.2	-1.6	-1.8	-1.8
Qualifications: College or University degree	0.9	2.8	7.5	-1.9	-1.9	-0.8	-1.6	-1.8	-2.2	-1.5	-2.0	0.2	-1.7	0.4	0.1	0.2	-1.0	-2.3	-2.7	-1.6	-1.9	-2.2
Angina (self-reported)	0.9	1.1	2.0	1.3	1.3	0.9	-0.6	1.3	0.5	0.8	1.2	1.2	1.4	-0.6	0.1	0.3	1.0	1.1	1.2	1.4	1.3	1.3
Had major operations	0.9	1.1	1.9	1.4	1.2	1.2	-0.8	1.2	0.8	0.9	1.2	0.5	1.1	-0.6	0.7	-0.3	1.1	1.4	1.2	0.8	1.4	1.2
Smoking status: Previous	0.9	1.4	9.6	0.7	0.4	0.1	-0.9	0.5	0.6	0.8	0.6	0.8	0.2	-3.1	-1.1	-1.8	2.2	1.0	1.4	-0.3	0.7	0.8
Friendships satisfaction	0.9	1.1	2.9	1.3	1.4	0.3	-0.4	1.2	-0.2	1.0	1.2	0.5	1.1	-0.4	0.8	1.3	1.7	1.1	0.8	1.4	1.3	1.1
Diastolic blood pressure, automated reading	0.9	2.9	5.6	-2.2	-2.1	-1.0	-1.4	-2.1	-1.4	-1.6	-2.0	-0.4	-2.4	0.5	-1.6	-0.1	-1.4	-2.2	-1.1	-2.1	-2.2	-2.2
Commuting to job workplace: Cycle	0.9	1.1	2.7	-1.1	-0.9	-1.1	-1.3	-0.9	-1.6	-1.1	-1.1	0.5	-1.1	0.0	-0.1	-0.6	-0.8	-1.2	-1.6	-0.8	-1.1	-1.1
Arm predicted mass (left)	0.9	4.6	10.7	-2.6	-2.7	-2.0	-0.7	-2.6	-1.9	-2.1	-2.4	0.7	-2.7	1.0	-1.4	0.2	-1.3	-2.4	-3.3	-2.4	-2.6	-2.6
Alzheimer’s Disease (in father)	0.8	0.9	1.9	-1.1	-1.1	-1.0	-0.1	-1.2	-0.6	-1.2	-1.1	0.3	-1.3	-0.6	-0.9	0.0	1.0	-0.8	-1.4	-0.8	-1.1	-1.1
Crohns Disease (2017)	0.8	1.9	9.1	-1.5	-1.4	-1.0	1.0	-1.4	0.1	-0.2	-1.5	-0.7	-1.1	-2.2	-0.8	-3.0	-0.0	-1.4	0.8	-1.4	-1.5	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.3	1.2	1.1	0.1	0.8	1.0	0.9	0.0	1.2	0.2	1.2	0.2	1.5	0.4	0.8	1.8	1.2	1.0	1.2	1.4
Relative age voice broke	0.8	1.2	4.5	-1.3	-1.2	-0.5	0.2	-1.0	-1.7	-0.7	-1.2	-1.6	-0.7	-0.1	-0.6	-0.5	-0.8	-2.1	-0.2	-1.2	-1.3	-1.5
Qualifications: None of the above	0.8	1.6	3.9	1.6	1.6	0.2	0.5	1.5	1.2	0.5	1.7	-0.9	1.5	0.2	1.0	0.4	0.0	2.0	1.8	1.2	1.6	1.8
Diabetes (self-reported)	0.8	1.2	2.4	1.2	1.2	1.5	0.6	1.3	0.9	0.9	1.5	-0.0	1.4	0.7	1.5	-0.2	-0.6	0.8	1.6	1.0	1.2	1.1
Time employed in main current job	0.8	1.0	4.7	1.0	1.0	0.9	0.2	1.0	0.7	1.2	1.0	0.8	1.0	0.3	0.5	2.2	0.2	1.0	0.4	1.2	1.0	1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	5.8	-2.0	-2.1	-1.6	-0.1	-2.1	-1.3	-1.6	-2.0	0.2	-2.3	-0.4	-2.1	-0.7	0.5	-1.4	-2.4	-1.5	-2.0	-2.0
Medication: Cholesterol lowering	0.8	1.3	3.3	1.2	1.4	1.8	-0.7	1.3	0.7	0.7	1.2	1.2	1.4	0.0	0.4	1.3	-0.3	1.0	1.4	1.2	1.2	1.3
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.8	0.8	1.1	1.0	1.3	0.8	1.3	0.9	0.6	0.4	0.8	-0.1	1.3	0.1	0.4	1.1	1.7	0.9	0.8	0.9
Age at first live birth	0.8	1.3	10.4	0.2	0.1	1.1	0.4	0.2	-0.5	0.1	0.2	0.7	0.1	3.2	0.1	3.0	-1.3	-0.1	-1.4	0.5	0.2	-0.0
Pulse wave peak to peak time	0.8	1.0	2.1	1.2	1.2	0.7	0.8	1.2	1.0	0.5	0.9	-0.3	1.2	-0.2	0.3	1.4	0.7	1.4	0.7	1.3	1.2	1.2
Neck or shoulder pain in last month	0.8	1.2	4.1	-1.1	-0.9	-1.1	-1.5	-1.1	-1.9	-2.0	-0.9	-0.9	-0.8	0.6	-0.8	1.2	0.4	-0.9	-0.3	-0.8	-1.1	-1.0
Illnesses of siblings: Diabetes	0.8	1.0	4.4	0.0	0.1	-1.0	-1.1	-0.1	-0.6	-0.4	-0.3	1.5	-0.6	-2.1	-1.5	-2.0	1.7	0.1	0.4	-0.2	0.0	-0.0
Long-standing illness, disability or infirmity	0.8	1.3	3.6	1.2	1.4	1.7	-0.3	1.4	1.1	1.1	1.5	0.3	1.3	-0.8	-0.5	-0.3	0.5	0.8	1.9	1.1	1.2	1.2
Tinnitus: Yes, now most or all of the time	0.8	1.0	5.2	0.7	0.6	-0.7	2.3	0.6	1.3	1.2	0.5	-0.9	0.6	0.2	1.6	-1.3	-0.3	0.9	0.1	0.6	0.7	0.8
Average weekly beer plus cider intake	0.8	1.2	8.7	-0.8	-1.0	-0.3	-1.4	-0.9	-0.0	-0.8	-0.9	1.0	-0.8	-1.6	-2.9	1.2	1.3	-0.2	0.1	-0.7	-0.8	-0.6
Alcohol drinker status: Previous	0.8	0.9	2.2	1.0	1.0	0.7	-0.4	1.1	0.8	0.4	1.1	-0.7	1.0	0.0	0.6	-1.1	-1.5	1.0	1.2	0.6	1.0	1.1
Blood White Count	0.7	5.0	16.9	1.6	1.4	4.1	2.5	1.6	2.9	1.3	1.6	2.7	1.1	4.0	3.7	0.6	-0.3	1.4	0.2	2.5	1.6	1.6
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.7	-0.5	-0.8	-0.3	-0.7	-0.6	-0.4	-1.5	-0.8	-1.9	-0.5	1.2	-0.0	0.4	-1.5	-0.1	0.5	-1.1	-0.5	-0.3
Maternal smoking around birth	0.7	1.0	7.4	0.6	0.8	-1.2	-0.3	0.5	0.1	0.9	0.6	-2.7	0.5	-0.9	0.0	-1.5	-0.0	0.7	1.7	0.1	0.6	0.6
Age when periods started (menarche)	0.7	1.7	3.7	-1.5	-1.7	-0.2	-0.8	-1.5	-1.2	-1.2	-1.5	0.9	-1.9	0.2	-0.4	1.3	-0.0	-1.7	-1.9	-1.0	-1.5	-1.7
Hair/balding pattern: Pattern 2	0.7	0.9	9.6	-0.2	-0.4	-1.9	0.3	-0.4	-0.1	-0.8	-0.4	-1.4	-0.1	0.2	3.1	-0.7	-0.4	0.5	-0.6	-0.4	-0.2	-0.0
Forced vital capacity (FVC)	0.7	2.6	5.3	-1.8	-2.0	-1.6	-0.2	-1.9	-1.2	-1.6	-1.8	0.7	-2.2	-0.9	-2.3	-1.0	1.2	-1.2	-2.2	-1.3	-1.8	-1.8
Pain all over the body in last month	0.7	0.7	3.0	0.7	0.9	0.6	1.2	0.8	0.3	0.9	0.9	-1.7	0.8	0.9	1.4	-0.8	-0.5	0.2	0.6	0.5	0.7	0.6
Weight	0.7	3.6	6.2	-2.4	-2.4	-1.4	-0.4	-2.4	-1.4	-1.7	-2.1	0.6	-2.5	1.3	-1.7	0.7	-1.7	-2.1	-2.4	-2.3	-2.4	-2.2
Worrier / anxious feelings	0.7	1.3	4.7	0.8	1.0	0.6	2.2	0.8	0.8	0.9	0.7	-1.7	0.6	1.9	2.1	0.2	-1.2	0.5	1.0	0.7	0.8	0.7
Mouth/teeth dental problems: Dentures	0.7	1.3	3.2	1.2	1.4	1.1	-0.3	1.3	1.2	1.1	1.3	0.5	1.4	-0.9	-0.1	-1.4	0.2	1.2	1.8	1.0	1.2	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	4.6	-1.8	-1.8	-1.5	-0.3	-1.8	-1.6	-1.3	-1.7	-0.4	-1.8	0.4	-1.9	0.3	-0.2	-1.6	-2.1	-1.4	-1.8	-1.8
High blood pressure (siblings)	0.7	1.0	6.6	0.0	0.1	0.0	-1.4	0.1	-0.2	0.5	0.2	0.1	-0.3	-2.6	-1.9	-2.1	1.0	-0.5	1.2	-0.4	0.0	-0.1
Medication: Omeprazole	0.7	0.8	2.1	-0.9	-0.8	-0.6	-1.4	-0.9	-0.9	-0.9	-0.9	0.4	-1.0	-1.1	-1.4	-0.3	1.0	-0.9	-0.5	-0.4	-0.9	-0.9
Knee pain experienced in last month	0.7	1.0	3.7	1.1	1.4	0.1	-0.9	1.3	0.1	1.2	1.2	0.6	1.2	0.6	1.9	0.6	-0.3	0.8	0.4	1.2	1.1	1.1
Mood swings	0.7	1.2	4.3	1.1	1.3	0.3	0.3	1.1	0.4	1.1	1.2	0.9	1.1	-1.7	-0.4	1.0	2.1	0.8	1.1	1.4	1.1	1.0
Commuting to job workplace: Walk	0.7	0.7	4.7	-0.6	-0.6	-1.0	-2.2	-0.6	-1.4	-0.8	-0.6	-0.4	-0.5	0.5	0.0	0.1	-0.3	-0.8	-1.0	-0.6	-0.6	-0.7
Osteoporosis (self-reported)	0.7	0.9	3.2	-1.0	-1.0	-0.3	-1.8	-1.0	-1.5	-0.8	-1.2	-0.5	-0.9	-0.1	0.0	0.4	-0.2	-1.1	-0.5	-1.3	-1.0	-1.1
Medication: Gliclazide	0.7	0.7	3.7	0.7	0.9	0.5	1.9	0.8	1.3	1.1	0.8	-0.5	0.9	-0.5	0.6	-0.6	0.0	0.6	0.6	0.7	0.8	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	8.1	0.7	0.8	2.0	1.5	0.7	1.2	0.9	1.0	1.0	0.5	2.8	0.9	0.4	-1.0	0.6	0.0	1.4	0.7	0.7
Fractured/broken bones in last 5 years	0.7	0.9	3.1	0.9	0.7	1.7	-1.8	0.8	0.6	0.4	0.6	1.6	0.7	0.4	-0.6	1.2	0.4	1.2	0.6	0.6	0.9	1.0
Medication for hormone replacement therapy	0.6	0.6	2.9	-0.1	0.1	-1.6	-0.7	0.0	-1.2	0.4	0.0	-1.7	0.3	0.7	0.4	-0.4	-1.3	-0.6	-1.4	0.1	-0.1	-0.3
Diabetes (mother)	0.6	0.8	3.5	-0.6	-0.5	-0.9	1.9	-0.6	0.0	-0.3	-0.6	-1.0	-0.6	0.6	0.3	-1.9	-1.1	-0.8	-0.6	-0.8	-0.6	-0.7
Pack years adult smoking proportion	0.6	0.9	2.1	-1.2	-0.9	-0.9	0.1	-1.1	-0.7	-1.0	-1.1	-0.9	-1.3	0.1	0.8	-1.5	-1.4	-0.9	-0.3	-1.0	-1.2	-0.9
Average weekly fortified wine intake	0.6	0.7	3.1	0.6	0.6	1.4	-1.2	0.7	-0.1	0.3	1.1	0.1	0.7	1.8	0.3	1.4	-0.3	0.4	0.6	0.7	0.6	0.6
Past tobacco smoking	0.6	1.1	6.3	-0.9	-0.7	-0.2	0.8	-0.7	-0.6	-0.7	-0.8	-0.2	-0.3	2.5	0.9	1.9	-1.5	-1.1	-1.4	0.2	-0.9	-0.9
Heart attack	0.6	0.8	4.0	0.3	0.1	0.4	-0.0	0.1	0.7	0.1	0.3	0.4	-0.0	-2.0	-1.6	-1.3	1.4	0.7	1.6	-0.2	0.3	0.4
Falls in the last year	0.6	0.8	2.6	-0.8	-0.6	-1.2	0.1	-0.9	-1.0	-0.8	-0.9	-1.1	-1.0	0.5	1.1	-0.1	-0.5	-0.9	-1.6	-0.9	-0.8	-0.9
Illnesses of mother	0.6	0.7	1.9	-0.8	-0.8	-1.0	-0.7	-0.8	-0.8	-0.9	-0.8	-0.7	-0.5	0.7	-0.2	1.4	-1.2	-0.5	-1.2	-1.0	-0.8	-0.7
Breastfed as a baby	0.6	0.8	6.1	-0.1	-0.2	0.3	0.0	-0.2	-0.3	-0.1	-0.1	1.0	-0.2	0.3	-1.0	2.5	2.1	-0.1	-1.2	0.3	-0.2	-0.2
Number of children fathered	0.6	0.7	5.9	0.2	0.3	-0.3	-0.6	0.1	-0.2	0.6	0.1	1.9	-0.0	-1.4	0.2	-0.8	2.4	0.2	-0.2	0.5	0.2	0.1
Number of full sisters	0.6	0.7	6.2	0.8	0.7	0.4	-2.5	0.8	-0.7	-0.2	1.0	0.4	0.6	0.4	0.8	0.5	0.3	0.6	0.1	0.6	0.8	0.7
Illnesses of father: None of the above (group 1)	0.6	0.7	1.3	-1.1	-1.0	-0.2	0.3	-1.0	-0.6	-0.5	-1.0	-0.9	-1.1	-0.2	-0.4	-1.0	-0.6	-1.1	0.3	-1.1	-1.1	-1.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.9	0.6	0.8	-0.1	0.8	0.9	0.4	1.4	1.0	-0.7	1.3	0.4	0.6	1.2	0.0	-0.0	0.9	1.2	0.6	0.5
Number of operations (self-reported)	0.6	0.9	7.6	0.6	0.7	1.6	-2.8	0.6	-0.7	0.5	1.0	0.3	0.6	1.2	1.2	0.3	-0.2	0.1	0.5	0.4	0.6	0.5
Risk taking	0.6	0.9	2.7	0.9	0.8	0.9	0.8	0.9	1.3	1.4	1.0	-0.3	0.8	-0.4	-0.3	0.3	1.6	0.8	0.8	1.1	0.9	0.9
Ever depressed for a whole week	0.6	0.7	1.8	-0.9	-0.7	-1.2	0.0	-0.8	-1.3	-0.8	-0.8	-0.7	-0.8	0.2	1.1	-0.0	-0.5	-1.3	-1.0	-0.7	-0.9	-1.0
Bipolar Disorder (2018)	0.5	0.8	3.1	0.7	0.5	1.7	-0.5	0.7	0.6	1.0	0.8	1.7	0.7	0.1	-0.7	0.3	1.7	0.6	-0.4	1.0	0.7	0.5
Depression (Nagel 2018)	0.5	0.8	4.8	0.3	0.5	-0.9	0.6	0.2	-0.6	-0.2	0.4	-2.1	0.3	1.4	2.2	0.4	-0.8	0.4	0.9	-0.1	0.3	0.3
Schizophrenia vs Biploar Disorder	0.5	0.7	1.7	0.6	0.8	-1.3	-0.5	0.7	0.1	0.6	0.7	-1.2	1.1	-0.7	0.8	-1.3	-0.9	0.4	1.0	0.3	0.6	0.7
Mean Putamen Volume	0.5	0.6	2.3	-0.5	-0.5	-0.9	0.9	-0.5	-0.2	0.0	-0.7	-0.1	-0.2	1.5	0.6	1.5	-0.3	-0.6	-1.2	0.0	-0.5	-0.6
HbA1C	0.5	0.6	3.3	-0.9	-0.7	-0.8	0.0	-0.9	-0.4	-1.8	-1.1	0.8	-0.9	0.1	-0.2	0.4	-0.0	-0.3	-0.6	-0.4	-0.9	-0.6
Primary Biliary Cirrhosis	0.5	0.7	2.9	-0.6	-0.5	-0.7	1.1	-0.6	-0.6	-0.3	-0.7	-0.4	-0.7	1.2	0.9	0.9	0.2	-1.1	-1.7	-0.1	-0.6	-0.8
Schizophrenia (2014)	0.5	1.0	3.9	-0.9	-0.8	-1.3	-1.0	-0.7	-1.3	-0.6	-0.8	-1.1	-0.5	-0.3	-0.3	-2.0	-1.1	-1.2	-1.1	-1.2	-0.9	-1.0
Heel T-Score	0.5	3.9	6.1	2.4	2.3	2.3	0.1	2.3	1.5	1.6	2.3	1.7	2.3	1.6	0.8	2.4	-0.1	2.5	1.2	2.5	2.4	2.4
Sensitivity / hurt feelings	0.5	0.8	2.6	0.9	1.2	0.7	0.3	0.8	0.3	0.4	0.8	-0.4	0.9	1.0	1.6	1.4	0.2	1.0	0.8	0.9	0.9	0.9
Hearing difficulty/problems: Yes	0.5	0.8	2.0	1.0	0.8	-0.3	-0.4	0.9	0.6	0.2	0.9	-1.2	1.1	-0.1	1.2	-0.3	-0.5	1.4	1.3	0.4	1.0	1.2
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.9	0.9	1.0	-0.1	-1.3	1.0	-0.3	1.1	0.9	-1.4	1.2	0.4	0.7	0.4	-0.4	0.3	0.4	0.6	0.9	0.7
Supplements: Zinc	0.5	0.6	1.7	-0.9	-0.8	-0.5	-0.3	-0.7	-0.5	-0.2	-0.8	-0.3	-0.6	0.3	-0.4	0.7	-0.8	-1.3	-1.2	-0.9	-0.9	-1.0
Townsend deprivation index at recruitment	0.5	0.6	2.2	0.8	0.7	0.3	-0.2	0.7	0.6	0.2	0.8	-1.5	0.8	-0.3	-0.6	0.7	0.6	1.3	0.9	0.8	0.8	1.0
Number of full brothers	0.5	0.7	2.9	0.8	0.8	0.5	0.9	0.8	1.1	0.5	0.8	0.4	0.2	-0.6	0.2	-0.4	0.3	1.2	1.7	0.6	0.8	1.0
Health satisfaction	0.5	0.6	3.6	-0.4	-0.2	0.2	-1.8	-0.4	-1.9	-0.2	-0.1	-0.8	-0.1	-0.4	0.3	0.6	0.8	-0.9	0.8	-0.7	-0.4	-0.6
Medication: Allopurinol	0.5	0.7	3.2	0.8	0.8	-0.3	-0.3	0.6	0.7	0.5	0.8	0.9	0.4	-1.4	-0.9	-0.5	1.8	1.1	0.5	0.7	0.8	0.8
Overall health rating	0.5	1.1	3.4	1.1	1.5	1.4	0.3	1.3	0.5	1.2	1.5	-0.3	1.2	-0.1	1.0	0.4	0.4	0.6	1.8	1.1	1.1	1.1
Age at last live birth	0.5	0.7	5.4	0.4	0.2	1.0	0.1	0.3	0.1	0.1	0.3	0.7	0.3	2.3	-0.1	2.1	-0.9	0.4	-0.7	0.3	0.4	0.3
Diabetes diagnosed by doctor	0.5	0.8	2.6	1.0	1.1	1.3	-0.3	1.1	0.7	0.4	1.3	0.5	1.3	-0.4	0.3	-0.2	0.0	0.8	1.6	0.9	1.0	1.0
Eye problems/disorders: Cataract	0.5	0.5	4.2	0.4	0.4	0.1	-0.3	0.5	0.3	0.1	0.6	-0.9	0.5	2.0	0.6	0.5	-1.3	0.4	1.0	0.3	0.4	0.5
Smoking status: Current	0.5	0.7	4.3	0.2	0.3	-0.5	1.3	0.1	0.2	0.0	0.0	-2.1	-0.1	0.8	1.0	-1.6	-1.6	0.2	0.5	-0.2	0.2	0.2
Average weekly champagne plus white wine intake	0.5	0.8	2.6	0.8	0.8	1.1	0.4	0.9	1.0	1.3	0.9	1.6	1.0	0.0	-0.5	1.0	0.3	0.6	-0.0	0.8	0.8	0.8
Ever taken oral contraceptive pill	0.5	0.5	1.8	-0.5	-0.7	0.2	-1.3	-0.6	-0.1	-0.9	-0.6	0.1	-0.8	-1.1	-1.3	0.4	0.1	-0.1	0.3	-1.2	-0.5	-0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.7	3.6	-0.4	-0.6	-0.1	-0.5	-0.5	0.0	-0.4	-0.3	0.0	-0.7	-1.8	-1.9	-1.2	1.0	-0.0	0.9	-0.8	-0.4	-0.3
Schizophrenia (2018)	0.4	0.9	4.4	-0.9	-0.9	-1.4	-0.6	-0.8	-0.8	-1.0	-0.9	-0.5	-0.7	0.2	-0.2	-2.1	-0.7	-0.9	-1.3	-1.1	-0.9	-0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	0.6	0.6	0.5	0.8	0.5	1.0	0.3	0.6	1.2	0.7	-1.0	0.2	-0.3	1.2	0.7	0.7	0.5	0.6	0.5
BMI	0.4	2.5	7.1	-1.8	-1.6	-0.6	0.3	-1.6	-1.4	-1.0	-1.5	-0.1	-1.6	2.3	-0.3	1.0	-2.7	-2.1	-2.3	-1.4	-1.8	-1.8
Smoking Status	0.4	1.0	9.2	0.3	0.2	-0.5	-0.5	0.1	0.0	0.1	0.1	-0.7	-0.3	-2.1	-0.6	-3.0	0.2	0.3	1.5	-1.0	0.3	0.3
Current tobacco smoking	0.4	0.7	4.6	0.1	0.2	-0.5	1.1	0.0	0.1	-0.0	-0.1	-2.1	-0.1	0.9	1.2	-1.6	-1.5	0.2	0.5	-0.3	0.2	0.2
Fed-up feelings	0.4	0.7	1.5	0.9	1.1	0.1	1.0	0.9	0.7	0.7	1.0	-0.1	0.8	0.1	0.8	1.0	1.2	0.8	1.1	1.1	0.9	0.9
Number of incorrect matches in round	0.4	0.6	3.1	-0.6	-0.7	0.5	1.4	-0.7	0.8	-0.2	-0.7	1.3	-0.8	-0.5	-0.2	-1.8	0.5	-0.6	-0.3	-0.4	-0.6	-0.5
Alcohol usually taken with meals	0.4	0.6	3.5	-0.5	-0.4	-0.4	-0.2	-0.3	-1.1	0.2	-0.4	-0.5	-0.5	0.5	-0.8	1.4	-0.6	-1.0	-1.9	-0.3	-0.5	-0.7
Had menopause	0.4	0.5	3.8	0.1	0.4	0.5	0.7	0.3	0.0	0.4	0.1	-0.6	0.3	1.5	1.9	0.5	-1.1	-0.4	-0.2	0.3	0.1	0.0
Had other major operations	0.4	0.5	5.0	0.2	0.2	0.7	-2.2	0.2	-0.9	-0.1	0.5	0.4	0.1	-0.1	0.6	1.0	0.6	-0.0	0.6	0.1	0.2	0.1
Mouth/teeth dental problems	0.4	0.7	2.7	-0.8	-0.9	-1.1	0.2	-0.7	-0.6	-0.0	-0.8	-0.1	-0.9	-0.1	-1.6	-0.5	-0.5	-1.2	-1.2	-0.7	-0.8	-1.0
Allergy	0.4	0.9	3.8	0.7	0.1	1.8	0.5	0.3	1.7	-0.2	0.4	2.0	0.4	0.4	0.9	-0.5	1.2	1.3	0.8	0.6	0.7	0.7
Medication: Ramipril	0.4	0.5	1.9	0.8	0.5	0.7	1.4	0.7	0.9	0.5	0.8	-0.1	0.6	0.9	0.3	0.5	0.1	0.8	0.3	1.0	0.8	0.8
Hip circumference	0.4	1.6	2.9	-1.6	-1.7	-0.8	-0.0	-1.6	-0.6	-0.9	-1.3	0.7	-1.7	0.5	-1.4	0.8	-0.9	-1.5	-1.5	-1.5	-1.6	-1.5
Standing height	0.4	3.7	7.3	-2.2	-2.4	-2.4	-1.5	-2.3	-2.0	-2.0	-2.2	-0.4	-2.3	0.5	-0.8	1.1	-1.1	-1.7	-2.7	-2.3	-2.2	-2.1
Length of working week for main job	0.4	0.4	1.6	-0.4	-0.6	-1.2	-0.4	-0.6	-0.3	-0.8	-0.5	-0.5	-0.5	0.4	-0.4	0.5	-0.8	-0.0	-1.3	-0.8	-0.4	-0.5
Gout (self-reported)	0.4	0.5	2.2	-0.6	-0.5	-1.5	-0.8	-0.6	-0.7	-0.3	-0.4	-1.1	-0.8	-0.3	-1.1	-0.1	-0.0	-0.6	-0.4	-1.0	-0.6	-0.6
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.8	0.5	0.4	1.8	1.1	0.4	1.2	0.2	0.5	1.0	-0.1	0.1	0.5	2.2	0.6	0.6	-0.1	0.8	0.5	0.5
Medication: Amlodipine	0.4	0.6	1.9	0.6	0.7	1.2	0.2	0.6	1.4	1.2	0.7	0.9	0.5	0.1	-0.5	-0.8	0.3	0.6	0.7	1.0	0.6	0.7
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.0	-0.0	-0.1	1.4	0.2	-0.2	1.1	-1.1	-0.2	1.3	-0.7	0.4	-0.0	-0.1	-0.5	1.0	0.8	-0.1	-0.0	0.3
Medication for pain relief, constipation, heartburn	0.4	0.8	2.2	-0.8	-1.0	-1.0	0.3	-1.0	-0.6	-1.3	-1.0	-1.2	-1.0	0.2	0.5	0.2	0.2	-0.4	-1.5	-1.0	-0.8	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.5	-0.3	-0.1	0.1	1.3	-0.2	-0.1	1.0	-0.4	0.1	-0.5	-1.6	-0.9	-1.1	0.9	-0.9	-0.1	-0.1	-0.3	-0.5
Chest pain or discomfort	0.4	0.6	1.8	0.8	0.9	0.3	-0.5	0.9	0.2	0.8	1.0	0.6	0.8	-0.4	-0.2	1.3	1.0	0.7	0.6	1.0	0.8	0.8
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	-0.6	-0.8	0.1	0.5	-0.8	0.3	-1.2	-0.8	0.9	-0.7	0.6	0.0	-0.2	-0.4	0.1	-0.7	-0.9	-0.6	-0.5
Medication: Aspirin	0.4	0.5	1.5	0.5	0.8	0.5	-0.0	0.8	0.6	1.1	0.9	1.2	0.9	-0.9	-0.9	-0.6	-0.1	0.1	0.9	0.8	0.5	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.5	0.5	0.6	0.5	0.0	0.6	0.3	-0.1	0.7	-0.3	0.7	1.6	1.4	-0.0	-1.2	0.4	0.1	0.3	0.5	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.5	-0.7	-0.6	-0.1	-0.5	-0.7	-1.0	-1.2	-0.5	0.2	-0.7	0.2	1.9	-0.1	0.9	-0.9	-0.5	-0.5	-0.7	-0.8
Medication for cholesterol	0.4	0.6	3.1	-0.0	-0.1	0.9	1.2	-0.1	1.2	-0.4	-0.3	1.8	-0.2	-0.6	-0.7	1.0	0.7	0.6	1.0	-0.0	-0.0	0.2
Breast cancer (self-reported)	0.4	0.5	4.6	0.1	0.2	1.1	1.2	0.0	0.6	0.1	-0.1	2.2	-0.2	-0.1	0.6	-0.0	1.0	0.2	0.1	0.8	0.1	0.1
Medication: Bendroflumethiazide	0.4	0.6	2.6	0.5	0.5	0.4	0.3	0.6	0.6	1.1	0.7	-1.1	0.5	-1.1	-1.6	-1.5	-0.1	0.0	0.7	0.4	0.5	0.5
Alcohol drinker status: Never	0.4	0.5	2.5	0.2	0.5	1.6	0.8	0.4	0.3	0.5	0.5	-0.3	-0.0	1.3	0.8	0.9	-0.2	-0.1	0.7	0.7	0.2	0.2
Pack years of smoking	0.4	0.6	1.7	-0.9	-0.7	-0.7	-0.0	-0.9	-0.5	-0.8	-0.8	-0.6	-1.0	-0.2	0.6	-1.3	-0.8	-0.7	-0.3	-0.7	-0.9	-0.7
Depressed Affect (Nagel 2018)	0.3	0.6	1.9	0.8	1.1	-0.2	-0.0	0.9	-0.1	0.7	1.1	-0.1	0.8	-0.3	0.6	1.1	1.4	0.5	1.1	0.9	0.8	0.7
Alzheimer’s Disease (in mother)	0.3	0.4	1.0	-0.2	-0.1	-1.0	0.6	-0.3	-0.5	-0.5	-0.4	-0.6	-0.2	0.8	1.0	-1.0	-0.8	-0.2	-0.8	-0.6	-0.2	-0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.4	0.8	0.5	1.3	-0.6	0.7	0.7	0.0	0.5	1.6	0.8	1.2	0.5	0.7	-0.6	1.0	0.4	0.7	0.7	0.8
Body Mass Index (BMI) (2010)	0.3	0.4	1.9	-0.5	-0.6	-0.3	-0.5	-0.6	-0.4	-0.8	-0.5	0.7	-0.5	1.1	-0.5	0.1	0.6	-0.4	-1.4	-0.3	-0.5	-0.6
Fasting Glucose	0.3	0.4	1.9	-0.5	-0.3	-0.3	-1.4	-0.5	-1.2	-0.7	-0.4	0.1	-0.6	-0.6	-0.4	0.1	-0.0	-0.5	-0.1	-0.9	-0.5	-0.4
Rheumatoid Arthritis	0.3	0.4	1.7	-0.4	-0.6	-1.3	0.4	-0.6	-0.4	-1.0	-0.7	-0.8	-0.6	-0.7	0.7	-0.8	1.0	0.1	-0.3	-0.3	-0.4	-0.3
Hypothyroidism (self reported)	0.3	0.7	7.4	-0.0	0.0	1.4	0.1	-0.1	0.2	-0.4	0.1	1.1	-0.5	0.5	0.8	2.7	0.4	-0.0	-0.5	0.4	-0.0	-0.0
Chronotype (morning person)	0.3	0.7	2.8	-0.4	-0.8	-0.9	-0.8	-0.6	-0.2	-1.0	-0.5	1.3	-0.6	-0.9	-1.7	1.6	0.5	0.1	-1.2	-0.3	-0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.2	0.9	0.8	1.8	-0.2	0.9	0.8	0.7	0.9	-0.0	0.9	0.4	0.2	0.9	-0.5	1.0	0.8	0.8	0.9	0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.6	0.6	-0.0	0.0	0.6	0.0	1.1	0.5	-0.3	0.6	-0.1	0.5	0.6	0.2	0.6	1.0	0.5	0.6	0.5
Sitting height	0.3	2.0	4.9	-1.6	-1.7	-1.5	-1.1	-1.7	-1.4	-1.2	-1.6	-0.2	-1.6	0.9	-0.4	0.6	-0.7	-1.4	-2.2	-1.7	-1.6	-1.6
Body mass index (BMI)	0.3	1.3	2.3	-1.4	-1.4	-0.3	0.2	-1.3	-0.5	-0.8	-1.1	0.8	-1.5	1.2	-1.4	0.4	-1.3	-1.3	-1.2	-1.3	-1.4	-1.3
Trunk fat mass	0.3	1.1	2.6	-1.2	-1.3	-0.4	-0.1	-1.2	-0.4	-0.6	-1.0	0.4	-1.3	0.9	-1.1	1.1	-1.6	-1.1	-1.0	-1.3	-1.2	-1.1
Waist circumference	0.3	1.1	1.9	-1.2	-1.3	-0.7	-0.2	-1.3	-0.4	-0.9	-1.0	0.8	-1.3	0.9	-1.2	0.9	-1.2	-1.0	-1.4	-1.1	-1.2	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.3	0.4	0.4	1.5	-1.6	0.5	-0.5	-0.4	0.6	-0.2	0.5	0.8	0.4	1.8	-1.2	0.3	0.4	0.5	0.4	0.5
Fluid intelligence score	0.3	0.7	2.2	1.0	0.8	0.7	-0.9	0.9	0.3	0.4	0.8	1.5	1.1	0.6	-0.0	0.5	0.2	0.9	-0.2	1.1	0.9	0.9
Father’s age at death	0.3	0.4	1.6	0.5	0.7	-0.4	0.4	0.6	0.4	0.8	0.7	-0.7	0.4	-0.8	0.4	-0.2	-0.4	0.4	1.3	0.2	0.5	0.5
Number of live births	0.3	0.4	1.5	0.5	0.3	0.0	-0.5	0.4	0.8	0.3	0.3	1.2	0.2	-1.0	-1.2	0.2	1.2	0.8	-0.2	0.2	0.5	0.5
Happiness	0.3	0.3	2.0	0.5	0.5	-0.3	-1.4	0.6	-0.8	0.2	0.7	-0.0	0.5	-0.4	-0.3	0.2	1.0	0.1	0.4	0.2	0.5	0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	3.3	-0.0	-0.2	0.5	-0.2	-0.2	-0.2	-0.6	-0.2	0.7	-0.2	0.9	0.7	1.8	0.5	0.4	-0.6	0.0	-0.0	0.0
Medication: Paracetamol	0.3	0.5	1.8	0.7	0.7	0.4	0.6	0.7	0.8	0.6	0.7	1.3	0.6	0.7	1.0	-0.2	0.3	0.7	0.5	0.7	0.7	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.6	-0.3	-0.2	-0.7	-0.1	-0.3	-0.5	-0.8	-0.3	-1.6	-0.6	0.7	0.8	-0.6	-1.0	-0.3	-0.3	-0.4	-0.3	-0.3
Shortness of breath walking on level ground	0.3	0.4	1.8	-0.0	-0.0	-0.7	-1.3	-0.1	-1.1	-0.2	-0.0	-1.3	-0.2	-0.0	1.1	-0.1	-0.8	-0.1	0.5	-0.6	-0.0	0.0
Eye problems/disorders: None of the above	0.3	0.4	1.7	-0.3	-0.4	-0.5	-0.4	-0.5	-0.2	-0.6	-0.6	1.0	-0.6	-1.3	-0.1	-0.4	1.2	0.2	-0.8	-0.3	-0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	0.4	0.4	0.2	-0.7	0.4	0.2	0.6	0.1	-0.6	0.3	-1.4	-1.0	0.2	-0.2	0.5	1.3	0.1	0.4	0.5
Emphysema/chronic bronchitis	0.3	0.4	1.2	0.5	0.6	0.2	-0.7	0.5	0.2	0.7	0.6	0.7	0.2	-1.0	-1.1	-0.8	0.9	0.4	0.1	0.6	0.5	0.4
Migraine (self-reported)	0.3	0.4	3.6	-0.0	0.1	0.8	-0.5	-0.1	0.2	-0.5	-0.1	1.9	-0.1	-0.9	-0.2	0.5	1.0	0.3	0.8	0.0	-0.0	0.1
Heart disease (mother)	0.3	0.4	1.5	0.8	0.7	0.1	-0.2	0.8	0.3	0.6	0.7	0.1	0.5	0.3	-0.1	0.4	0.4	0.9	0.7	1.2	0.8	0.9
Leg fat mass (right)	0.3	1.0	2.8	-1.2	-1.2	0.0	0.1	-1.2	-0.2	-0.8	-0.8	0.5	-1.3	1.4	-0.6	0.7	-1.7	-1.0	-0.8	-1.2	-1.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-0.6	-0.5	-0.8	-0.3	-0.6	-0.4	-0.1	-0.6	0.4	-0.8	-0.7	-1.1	-1.2	0.4	-0.6	-0.0	-0.5	-0.6	-0.6
Illnesses of father: Heart disease	0.3	0.4	1.8	0.6	0.5	-0.5	-0.1	0.5	0.2	0.4	0.6	-1.3	0.5	0.1	-0.5	1.3	0.1	0.6	0.1	0.5	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.2	-0.8	-0.8	-0.5	-1.1	-0.7	-1.1	-0.4	-0.7	-0.4	-0.7	-0.1	-0.9	0.1	-0.0	-1.1	-0.4	-1.0	-0.8	-0.9
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.6	-0.4	-0.3	0.4	-1.2	-0.3	-1.1	-0.3	-0.4	0.0	-0.3	0.3	0.6	0.2	0.2	-0.8	-1.3	-0.4	-0.4	-0.6
Ever had bowel cancer screening	0.3	0.3	1.4	0.5	0.5	-0.5	-1.1	0.4	-0.1	0.5	0.5	-0.2	0.6	-1.2	0.4	-0.0	0.8	0.6	0.5	0.1	0.5	0.5
Qualifications: nursing, teaching	0.3	0.5	3.9	-0.2	-0.2	0.8	-0.8	-0.1	-0.7	-0.1	-0.2	0.8	0.0	1.1	-0.1	2.0	-0.1	-0.6	0.4	0.4	-0.2	-0.3
Back pain experienced in last month	0.3	0.4	1.6	0.5	0.5	-0.2	-1.1	0.5	-0.0	0.1	0.6	0.5	0.8	-1.1	-0.5	-0.8	0.5	0.7	1.3	0.0	0.5	0.5
Arm fat mass (left)	0.3	1.0	1.9	-1.2	-1.2	-0.2	0.0	-1.2	-0.4	-0.5	-0.9	0.8	-1.4	0.9	-1.3	0.6	-1.2	-1.2	-1.2	-1.2	-1.2	-1.1
Hearing aid user	0.3	0.3	1.2	0.2	0.3	1.0	-0.7	0.2	0.1	0.4	0.3	1.0	0.5	-1.1	-0.1	-0.3	1.0	-0.1	0.6	0.1	0.2	0.0
Mother’s age at death	0.3	0.4	2.0	0.3	0.5	0.3	0.8	0.4	0.6	0.4	0.4	-0.2	0.5	-1.4	-0.3	0.4	0.4	0.2	1.4	0.1	0.3	0.3
Illnesses of father: High blood pressure	0.3	0.4	2.2	0.5	0.5	1.5	0.0	0.6	0.7	0.3	0.7	1.1	0.9	0.7	0.4	0.1	-0.6	0.4	0.6	0.5	0.5	0.5
Ever smoked	0.3	0.6	3.6	0.4	0.3	-0.2	-0.9	0.3	-0.1	0.3	0.3	-0.8	-0.0	-1.5	-0.2	-1.9	0.3	0.5	1.3	-0.6	0.4	0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	2.9	-0.3	-0.2	-0.5	-1.2	-0.3	-0.3	-0.4	-0.2	0.1	-0.4	-0.6	-1.7	-0.2	0.8	-0.3	-0.0	0.1	-0.3	-0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	1.1	-0.4	-0.5	-1.1	0.1	-0.6	-0.5	-0.9	-0.7	-0.0	-0.7	0.3	-0.1	-0.3	0.0	-0.3	-1.1	-0.7	-0.4	-0.6
LDL Cholesterol	0.2	0.3	2.6	-0.1	-0.1	0.4	-0.5	-0.1	-0.1	-0.5	-0.0	0.8	-0.2	0.3	-1.6	0.5	0.5	-0.1	-1.1	-0.2	-0.1	-0.1
Cardiovascular Disease	0.2	0.5	1.9	-0.8	-0.6	-0.6	0.7	-0.6	-0.8	-0.0	-0.6	-0.3	-0.5	0.0	-0.9	0.4	0.0	-1.4	-1.3	-0.4	-0.8	-1.0
Lung FEV1/FVC ratio	0.2	1.2	3.6	-1.2	-1.1	-0.8	1.3	-1.1	-0.4	0.1	-1.1	-1.2	-0.9	0.5	0.3	-1.5	-1.9	-1.5	-0.8	-1.1	-1.2	-1.4
Tanning	0.2	2.4	6.4	2.1	1.8	0.9	0.2	1.8	1.5	1.1	1.6	0.9	1.6	-0.6	0.0	-1.1	1.8	2.5	1.2	1.8	2.1	2.1
Relative age of first facial hair	0.2	0.4	2.5	0.2	0.2	0.4	-0.6	0.4	-0.6	0.7	0.3	0.6	0.4	-1.6	-1.0	-0.8	1.1	-0.6	-0.2	0.3	0.2	-0.0
Systolic blood pressure, automated reading	0.2	0.5	2.2	0.7	0.6	0.0	-0.3	0.7	0.9	0.6	0.8	-0.4	0.8	-0.0	-0.7	-0.4	-0.2	0.8	1.5	0.3	0.7	0.8
Medication: Atenolol	0.2	0.3	1.8	0.2	0.1	0.6	-1.3	0.2	0.0	-0.6	0.2	0.4	0.2	0.6	-0.8	1.2	0.3	0.4	0.1	0.2	0.2	0.3
Financial difficulties in last 2 years	0.2	0.3	1.1	-0.4	-0.1	0.8	0.8	-0.1	-0.1	0.7	0.1	0.2	-0.3	-1.1	-0.2	-1.0	0.1	-1.0	0.3	-0.1	-0.4	-0.5
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.0	0.2	0.7	0.2	-0.1	0.5	-0.6	1.0	0.4	-0.2	0.6	-0.7	-0.1	0.5	0.3	-0.6	-0.2	0.6	0.2	0.0
Noisy workplace	0.2	0.2	0.9	-0.2	-0.2	0.3	0.5	-0.3	0.2	-0.1	-0.1	0.0	-0.2	-0.5	0.8	-0.9	-0.0	-0.0	1.0	-0.8	-0.2	-0.2
Lung cancer (father)	0.2	0.2	1.3	0.2	0.2	0.2	-0.8	0.1	-0.7	0.2	0.2	0.3	-0.0	0.7	-0.2	1.1	-0.3	-0.1	-0.5	0.1	0.2	0.0
Arm fat mass (right)	0.2	1.0	1.9	-1.2	-1.2	-0.1	0.3	-1.2	-0.2	-0.4	-0.9	0.8	-1.3	0.8	-1.4	0.5	-1.3	-1.2	-1.1	-1.2	-1.2	-1.1
Birth weight of first child	0.2	0.3	2.6	-0.2	-0.5	-0.3	0.5	-0.4	0.0	-0.5	-0.4	-0.5	-0.5	0.5	0.2	1.6	-0.9	0.2	-0.2	-0.7	-0.2	-0.2
Loud music exposure frequency	0.2	0.2	1.4	0.1	0.1	0.7	0.5	0.1	0.1	0.4	0.2	1.0	0.0	0.4	1.2	-0.3	0.1	-0.1	-0.7	0.5	0.1	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.9	-0.2	-0.2	0.1	0.3	-0.2	0.1	0.1	0.0	0.9	-0.3	-1.4	-0.4	-0.3	0.9	-0.5	-0.3	-0.5	-0.2	-0.4
Whole body fat mass	0.2	0.9	1.6	-1.1	-1.1	-0.1	-0.2	-1.1	-0.3	-0.6	-0.8	0.8	-1.2	0.9	-1.2	0.8	-1.3	-1.0	-0.8	-1.1	-1.1	-1.0
Medication: Aspirin	0.2	0.3	1.8	0.1	0.3	-0.0	-0.4	0.3	0.1	0.5	0.4	0.8	0.4	-1.0	-1.3	-0.3	-0.4	-0.2	0.5	0.2	0.1	0.1
Wears glasses or contact lenses	0.2	0.3	1.9	0.1	-0.0	0.6	-1.4	0.1	0.2	-0.3	0.0	-0.1	0.1	0.2	-0.5	1.2	0.0	0.4	-0.7	0.1	0.1	0.3
Medication: Blood pressure	0.2	0.3	1.2	-0.4	-0.4	-0.4	-0.2	-0.3	-0.7	-0.0	-0.2	-0.9	-0.6	0.5	0.3	-0.5	-0.1	-0.9	-1.1	-0.0	-0.4	-0.6
Medication: Paracetamol	0.2	0.3	2.1	0.1	0.0	0.1	0.7	-0.0	0.5	-0.0	0.0	0.9	-0.0	1.5	1.2	0.4	-0.3	0.2	-0.4	0.3	0.1	0.2
Medication: Lisinopril	0.2	0.3	1.1	-0.5	-0.3	0.4	0.1	-0.3	-0.4	0.4	-0.1	0.5	-0.5	-0.6	-1.0	-0.9	0.1	-1.0	0.5	-0.6	-0.5	-0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.7	0.4	0.4	-0.2	0.4	0.3	0.3	0.2	0.3	0.4	0.4	-0.9	-0.2	-0.2	1.3	0.5	-0.1	0.8	0.4	0.5
Pain experienced in last month	0.2	0.3	3.2	-0.2	-0.5	0.4	0.5	-0.3	0.5	0.1	-0.4	0.2	-0.7	0.4	-0.4	1.0	0.4	-0.2	-1.8	0.1	-0.2	-0.3
Leg fat mass (left)	0.2	1.0	1.9	-1.2	-1.2	-0.1	-0.1	-1.2	-0.3	-0.8	-0.9	0.6	-1.3	1.1	-0.9	0.9	-1.4	-1.1	-0.9	-1.1	-1.2	-1.1
Bipolar Disorder or Schizophrenia	0.1	0.3	2.3	-0.2	-0.4	0.0	-0.8	-0.2	-0.2	-0.1	-0.2	0.8	-0.1	0.2	-0.6	-1.5	0.5	-0.4	-1.2	-0.3	-0.2	-0.4
Intelligence (Savage-Jansen 2018)	0.1	0.4	3.2	0.4	0.2	0.2	-1.8	0.4	-0.0	-0.2	0.3	1.6	0.6	0.3	0.1	0.4	-0.2	0.7	-0.6	0.2	0.4	0.4
Reaction Time	0.1	0.2	1.4	-0.1	-0.1	-0.8	0.3	-0.2	-0.1	-0.4	-0.1	0.4	0.2	1.1	0.1	0.5	0.4	0.1	-1.2	-0.0	-0.1	-0.1
Height	0.1	1.2	3.1	-1.3	-1.3	-1.2	-0.4	-1.1	-1.0	-0.4	-1.0	-0.1	-1.0	1.0	0.2	1.0	-1.8	-1.3	-1.2	-1.5	-1.3	-1.3
Lung FVC	0.1	0.4	1.7	-0.6	-0.8	-0.0	0.7	-0.7	0.3	-0.7	-0.7	0.5	-0.9	0.6	-0.7	-0.4	0.5	-0.1	-1.3	-0.1	-0.6	-0.5
Ever had hysterectomy (womb removed)	0.1	0.2	0.6	-0.3	-0.1	0.4	-0.8	-0.2	-0.7	0.2	-0.3	-0.4	-0.2	-0.6	0.3	-0.2	0.3	-0.8	0.3	-0.1	-0.3	-0.4
Trunk fat percentage	0.1	0.3	1.8	-0.3	-0.4	0.4	0.0	-0.3	0.5	0.0	-0.1	0.6	-0.4	0.7	-0.8	1.3	-1.1	-0.2	-0.0	-0.4	-0.3	-0.2
Qualifications: CSEs or equivalent	0.1	0.2	0.4	-0.4	-0.4	-0.4	0.5	-0.5	-0.4	-0.3	-0.6	-0.3	-0.6	0.0	-0.6	0.5	0.4	-0.2	0.2	-0.2	-0.4	-0.3
Serious illness, injury or assault to yourself	0.1	0.2	1.0	-0.1	0.0	0.8	-0.3	-0.1	0.1	0.1	0.0	-0.3	-0.0	0.4	0.2	-0.0	-1.0	-0.2	1.0	-0.6	-0.1	-0.1
High blood pressure	0.1	0.2	1.5	-0.0	0.2	0.2	0.6	0.2	-0.2	1.2	0.3	-0.0	0.2	0.6	-0.2	0.4	-0.4	-1.0	-0.3	0.4	-0.0	-0.3
Stomach or abdominal pain in last month	0.1	0.2	1.8	-0.1	0.2	-0.0	0.6	0.1	0.1	0.3	0.0	-0.6	0.0	0.4	1.4	0.0	-0.3	-0.3	0.2	0.3	-0.1	-0.1
Arm fat percentage (right)	0.1	0.3	1.2	0.1	0.1	1.1	0.8	0.1	1.0	0.8	0.4	0.8	0.1	0.7	-0.6	0.5	-0.9	-0.1	0.5	0.0	0.1	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.7	-0.1	0.1	-0.6	0.2	-0.1	-0.1	0.1	-0.1	-0.0	-0.1	-0.3	0.8	-0.6	-0.2	0.1	0.4	-0.4	-0.1	-0.0
Pulse rate	0.1	0.2	0.8	-0.2	-0.2	-0.4	0.9	-0.2	0.0	-0.1	-0.2	-0.4	-0.4	0.3	0.3	-0.8	0.5	-0.3	-0.9	0.6	-0.2	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.9	-0.7	-0.7	0.4	0.8	-0.4	0.1	-0.3	-0.4	0.6	-0.4	0.0	0.1	-0.8	-0.7	-0.9	-0.3	-0.3	-0.7	-0.7
Hair/balding pattern: Pattern 4	0.1	0.3	2.0	-0.3	-0.5	-0.1	-0.7	-0.5	-0.3	-1.4	-0.3	-0.0	-0.5	0.4	-0.9	0.4	0.1	0.2	0.2	-0.4	-0.3	-0.2
Headache pain in last month	0.1	0.2	0.9	-0.2	0.1	-0.4	-0.9	-0.1	-0.8	-0.3	0.0	-0.3	0.1	0.4	-0.4	0.9	-0.2	-0.2	0.9	-0.3	-0.2	-0.1
Body fat percentage	0.1	0.3	1.5	-0.0	-0.1	0.8	0.1	-0.0	0.7	0.2	0.2	0.8	-0.2	0.8	-0.8	1.2	-0.9	-0.0	0.3	-0.1	-0.0	0.1
Leg fat percentage (right)	0.1	0.4	1.8	-0.0	0.1	1.1	0.3	0.1	0.7	0.2	0.3	0.7	-0.1	1.3	-0.2	1.2	-1.2	-0.0	0.5	0.1	-0.0	0.2
Mean time to correctly identify matches	0.1	0.1	0.9	-0.1	-0.0	-1.0	0.1	-0.2	-0.0	-0.5	-0.1	-0.1	0.1	0.6	-0.2	0.1	0.1	0.2	-0.5	-0.3	-0.1	0.0
Pulse rate, automated reading	0.1	0.4	0.9	0.5	0.6	0.5	0.8	0.5	0.8	0.7	0.6	0.4	0.0	-0.7	-0.2	-0.8	1.0	0.3	0.6	1.0	0.5	0.6
Family relationship satisfaction	0.1	0.1	0.4	0.0	-0.0	0.6	-0.1	0.0	-0.1	-0.3	0.0	0.7	0.2	0.5	-0.0	0.2	0.0	-0.1	0.1	-0.1	0.0	-0.0
Hypertension (Self-reported)	0.1	0.3	1.6	-0.1	0.1	-0.1	0.9	0.2	-0.1	1.3	0.2	-0.5	0.2	0.2	-0.4	0.2	-0.6	-1.1	-0.3	0.3	-0.1	-0.4
Arm fat percentage (left)	0.1	0.3	1.1	-0.2	-0.1	0.8	0.3	-0.1	0.6	0.4	0.1	0.8	-0.2	0.8	-1.0	0.9	-1.0	-0.3	0.1	-0.2	-0.1	-0.1
Financial situation satisfaction	0.1	0.2	1.2	0.1	0.1	0.2	0.1	0.2	-0.7	0.7	0.3	0.2	0.1	0.3	-0.2	1.1	-0.7	-0.5	0.1	0.0	0.1	-0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.6	-0.5	-0.2	-0.2	0.2	-0.5	-0.4	0.0	-0.4	0.8	-0.2	0.0	0.2	-0.7	0.2	-0.6	0.3	-0.6	-0.5	-0.6
High cholesterol (Self-reported)	0.1	0.2	0.6	0.3	0.3	0.8	-0.4	0.3	-0.2	-0.1	0.6	0.3	0.6	-0.2	-0.1	0.8	0.7	0.1	0.2	0.6	0.3	0.3
Leg fat percentage (left)	0.1	0.3	2.0	0.0	0.1	1.0	0.2	0.1	0.6	0.3	0.3	0.9	0.0	0.9	-0.6	1.4	-0.7	-0.0	0.4	0.2	0.0	0.1
Myopia	0.1	0.2	1.1	-0.3	-0.4	-0.1	1.1	-0.4	0.2	-0.0	-0.3	-0.1	-0.4	-0.6	0.5	0.2	0.7	-0.0	-0.1	-0.3	-0.3	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.7	-0.6	-0.7	-0.4	-0.8	-0.7	-0.3	-1.3	-0.8	0.2	-0.7	-0.6	0.2	-0.7	0.1	0.1	-0.0	-0.9	-0.6	-0.4
Cholesterol lowering medication	0.1	0.1	0.4	0.3	0.2	0.6	0.5	0.3	0.5	-0.1	0.5	-0.2	0.4	0.2	0.3	-0.3	0.6	0.3	0.5	0.3	0.3	0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.2	1.3	0.2	0.1	-0.2	-0.6	0.1	-0.1	-0.3	0.0	1.0	0.0	0.3	-0.4	1.1	0.3	0.2	-0.9	0.1	0.2	0.2
Hair Pigment	0.0	0.2	1.5	0.1	0.0	0.3	-1.2	0.1	-0.4	-0.1	0.2	0.5	0.3	0.2	-0.6	-0.5	-0.4	0.1	0.2	-0.1	0.1	0.1
Comparative height size at age 10	0.0	0.2	0.9	-0.2	-0.4	-0.8	0.9	-0.4	0.5	-0.2	-0.3	0.4	-0.1	0.2	0.9	0.3	-0.4	0.2	-0.5	-0.5	-0.3	-0.1

Hub : Genes

MDM1

Models

Trait associations