TWAS hub - CXCL5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.121	0.0258	0	0.102	0.092	0.104	0.111	0.102	3.3e-31	3.7e-28	9.7e-32	5.9e-34	4.5e-31
2	YFS	Blood	0.181	0.0318	0	0.229	0.197	0.218	0.226	0.224	2.3e-73	3.0e-62	1.8e-69	2.9e-72	1.3e-71

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ulcerative Colitis (UC)	14.0	26.3	27.2	-5.0	-5.2
Ulcerative Colitis	10.9	15.9	15.9	-4.0	-4.0
Fasting Glucose	7.5	9.0	9.6	2.9	3.1
Irritable Bowel Disease (IBD)	5.8	13.9	14.5	-3.6	-3.8
Loneliness, isolation	5.6	7.7	7.9	2.7	2.8
Financial difficulties in last 2 years	5.3	7.1	8.1	2.8	2.5
Deep venous thrombosis (DVT) (self-reported)	4.1	5.3	6.7	-2.0	-2.6
Hair/balding pattern: Pattern 2	3.8	4.9	5.5	-2.0	-2.4
Basal cell carcinoma (self-reported)	3.8	4.6	5.0	2.2	2.0
Medication: Lansoprazole	3.6	4.1	4.5	-2.1	-1.9
Severe depression (siblings)	3.5	3.9	4.1	1.9	2.0
Pulse wave peak to peak time	3.5	4.1	4.9	-1.8	-2.2
Medication: Seretide 50 evohaler	3.4	4.0	4.2	-2.0	-1.9
Pulse wave Arterial Stiffness index	3.3	3.8	4.8	1.7	2.2
Mean Putamen Volume	3.2	3.6	3.8	-1.8	-2.0
Blood clot in the leg (DVT)	3.2	4.2	5.5	-1.7	-2.4
Medication: Gliclazide	3.1	3.6	4.3	-2.1	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	3.4	1.7	1.8
Supplements: Calcium	3.0	3.4	5.0	1.3	2.2
Diverticular disease/diverticulitis (self-reported)	2.9	3.5	3.7	-1.8	-1.9
Peak expiratory flow (PEF)	2.6	6.1	6.3	-2.5	-2.4
Chest pain or discomfort	2.6	3.8	4.1	-1.9	-2.0
Alcohol drinker status: Previous	2.6	3.0	5.0	1.0	2.2
Qualifications: A levels/AS levels or equivalent	2.5	5.5	7.6	2.8	1.8
Bipolar Disorder or Schizophrenia	2.4	5.9	7.1	-2.7	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	3.6	1.6	1.9
Ever smoked	2.4	4.2	4.6	2.1	2.0
Allergy	2.3	5.2	5.2	2.3	2.3
Risk taking	2.3	3.3	4.7	2.2	1.4
Ovarian Cancer	2.2	3.0	3.3	1.8	1.6
Primary Biliary Cirrhosis	2.2	3.1	3.3	-1.8	-1.7
Falls in the last year	2.2	3.0	4.7	1.1	2.2
Medication for cholesterol, blood pressure or diabetes	2.2	3.7	4.7	-1.6	-2.2
Neck or shoulder pain in last month	2.2	3.1	4.2	1.4	2.0
Lupus	2.1	3.1	3.9	1.6	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	2.6	1.6	1.6
Medication: Blood pressure	2.0	3.6	4.9	1.5	2.2
Medication: Aspirin	2.0	2.6	2.8	-1.7	-1.5
Schizophrenia (2014)	1.9	4.2	5.4	-2.3	-1.7
Frequency of tenseness / restlessness in last 2 weeks	1.9	3.0	4.2	-2.0	-1.3
Loud music exposure frequency	1.9	2.0	2.8	1.7	1.1
Body Mass Index (BMI) (2010)	1.8	2.5	3.1	1.8	1.4
Medication: Levothyroxine sodium	1.8	3.0	3.5	1.6	1.9
Hearing difficulty/problems with background noise	1.8	2.9	3.9	-1.4	-2.0
Pulse rate	1.8	3.0	4.5	1.2	2.1
Migraine (self-reported)	1.8	2.3	2.8	1.3	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.1	2.2	-1.5	-1.4
Major Depression (MDD)	1.7	2.1	2.4	1.4	1.5
Vitamin and mineral supplements	1.7	2.3	3.1	-1.2	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	3.1	1.8	1.1
Bipolar Disorder (2018)	1.6	2.6	2.7	-1.6	-1.6
Schizophrenia (2018)	1.6	3.4	4.5	-2.1	-1.5
Time employed in main current job	1.6	1.9	2.5	1.6	1.1
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	2.8	-1.1	-1.7
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	2.0	-1.3	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.0	4.0	2.0	1.5
Qualifications: CSEs or equivalent	1.4	1.9	2.2	1.2	1.5
Medication: Ibuprofen	1.4	1.6	2.3	1.5	1.0
Medication: Aspirin	1.4	1.9	2.0	-1.4	-1.3
Medication: Blood pressure	1.4	2.7	3.8	-1.9	-1.3
Ever highly irritable/argumentative for 2 days	1.3	1.6	1.8	-1.1	-1.4
Number of children fathered	1.3	1.5	1.8	-1.4	-1.0
Illnesses of father: High blood pressure	1.3	1.6	1.7	-1.2	-1.3
Glaucoma (self-reported)	1.2	1.4	1.4	1.2	1.1
Comparative body size at age 10	1.2	3.2	3.7	1.6	1.9
Medication for hormone replacement therapy	1.1	1.2	1.6	0.9	1.3
Number of incorrect matches in round	1.1	1.8	1.8	1.4	1.4
Medication: Simvastatin	1.1	1.6	2.2	1.0	1.5
Depression (self-reported)	1.1	1.3	1.6	1.3	1.0
Alzheimer’s Disease (in mother)	1.0	1.1	1.2	-1.0	-1.1
Bipolar Disorder (2011)	1.0	1.0	1.4	-0.7	-1.2
Current tobacco smoking	1.0	1.6	1.6	1.3	1.2
Age when periods started (menarche)	1.0	2.3	2.5	-1.6	-1.5
Supplements: Glucosamine	1.0	1.3	1.5	-1.2	-1.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	1.4	1.0	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.1	-1.5	-0.5
Illnesses of siblings: Diabetes	1.0	1.2	2.0	-1.4	-0.6
Wears glasses or contact lenses	1.0	1.2	1.8	0.7	1.3
Medication: Paracetamol	1.0	1.5	1.5	1.2	1.2
Fractured/broken bones in last 5 years	1.0	1.3	1.4	-1.2	-1.1
Prostate Cancer	0.9	1.3	1.8	1.3	0.9
Townsend deprivation index at recruitment	0.9	1.2	1.7	-1.3	-0.9
Chronic bronchitis/emphysema (father)	0.9	1.0	1.3	0.8	1.2
Medication: Ramipril	0.9	1.2	1.5	0.9	1.2
Father’s age at death	0.9	1.2	1.4	-1.2	-1.0
Eye problems/disorders: None of the above	0.9	1.0	1.2	-1.0	-1.1
Back pain experienced in last month	0.9	1.3	1.9	1.4	0.9
Commuting to job workplace: Cycle	0.9	1.0	1.4	1.2	0.8
Hearing difficulty/problems: Yes	0.8	1.2	1.5	-1.0	-1.2
Angina	0.8	1.0	1.3	-1.1	-0.9
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	2.8	-1.7	-1.6
Age at last live birth	0.8	1.2	2.0	0.7	1.4
Smoking status: Current	0.8	1.2	1.3	1.1	1.1
Guilty feelings	0.8	1.2	1.4	1.2	1.0
Hearing aid user	0.8	0.9	1.0	-1.0	-0.9
Eye problems/disorders: Glaucoma	0.8	1.0	1.0	1.0	1.0
Medication: Bendroflumethiazide	0.8	1.2	1.8	-1.3	-0.7
Serious illness, injury or assault to yourself	0.7	0.8	1.3	1.1	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.1	-1.1	-0.7
Asthma	0.7	1.5	1.8	-1.0	-1.3
Medication: Cholesterol lowering	0.7	1.1	1.3	0.9	1.2
High blood pressure (siblings)	0.7	1.0	1.1	1.0	1.0
Number of full brothers	0.7	0.9	1.4	-0.6	-1.2
Health satisfaction	0.7	0.9	1.0	0.9	1.0
Shortness of breath walking on level ground	0.7	0.8	0.9	0.9	0.9
Asthma (self-reported)	0.7	1.4	1.8	-1.0	-1.3
Number of self-reported non-cancer illnesses	0.7	1.3	1.5	1.1	1.2
Medication: Lisinopril	0.7	0.9	1.3	-1.1	-0.7
Cholesterol lowering medication	0.7	1.0	1.4	-1.2	-0.8
Pain experienced in last month	0.7	1.2	1.4	-1.2	-1.0
Heart disease (siblings)	0.7	0.9	1.2	-0.8	-1.1
LDL Cholesterol	0.6	0.9	1.6	-1.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	0.8	-0.8	-0.9
Number of live births	0.6	0.8	0.8	-0.9	-0.9
Tense / ‘highly strung’	0.6	0.9	1.2	-1.1	-0.8
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.8	1.3	0.3
Supplements: Vitamin C	0.6	0.7	1.3	0.4	1.1
Mood swings	0.6	1.1	1.7	-1.3	-0.8
Osteoarthritis (self-reported)	0.6	0.8	0.9	-0.9	-0.8
Average weekly beer plus cider intake	0.6	0.8	1.0	-1.0	-0.8
Schizophrenia vs Biploar Disorder	0.5	0.7	0.8	0.7	0.9
Rheumatoid Arthritis	0.5	0.7	1.0	-0.5	-1.0
Lung FVC	0.5	2.6	3.8	-1.9	-1.2
Sensitivity / hurt feelings	0.5	0.8	1.0	1.0	0.8
Relative age voice broke	0.5	0.8	0.8	-0.9	-0.9
Forced vital capacity (FVC)	0.5	2.0	2.2	-1.5	-1.4
Medication: Paracetamol	0.5	0.7	0.9	0.8	0.9
Medication: Amlodipine	0.5	0.7	0.8	0.7	0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	0.7	-0.8	-0.8
Had major operations	0.5	0.5	0.6	-0.8	-0.7
Knee pain experienced in last month	0.5	0.7	0.9	-1.0	-0.7
Average weekly red wine intake	0.5	0.8	1.1	1.0	0.6
Ever had bowel cancer screening	0.5	0.6	0.8	-0.7	-0.9
Myopia	0.5	0.7	0.9	0.7	0.9
Depression (Nagel 2018)	0.4	0.5	0.7	0.6	0.8
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.5	1.2	0.6
Coronary Artery Disease (CAD)	0.4	0.5	0.8	-0.3	-0.9
Average weekly spirits intake	0.4	0.5	0.7	0.5	0.9
Diabetes (father)	0.4	0.5	0.8	-0.3	-0.9
Diabetes (mother)	0.4	0.5	0.6	-0.8	-0.6
Trunk fat percentage	0.4	1.4	2.1	0.9	1.5
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.0	-1.0	-0.9
Nervous feelings	0.4	0.8	1.2	0.7	1.1
Mouth/teeth dental problems	0.4	0.6	0.8	0.6	0.9
Diabetes (self-reported)	0.4	0.6	0.7	-0.8	-0.8
Arm fat percentage (right)	0.4	1.5	2.1	0.9	1.4
Hip circumference	0.4	1.5	2.1	1.0	1.4
Happiness	0.4	0.5	0.8	-0.9	-0.5
Arm fat mass (right)	0.4	1.5	2.1	1.0	1.5
Length of working week for main job	0.4	0.5	0.5	-0.6	-0.7
Exposure to tobacco smoke at home	0.4	0.4	0.5	-0.6	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	0.6	0.8	0.8
Exposure to tobacco smoke outside home	0.4	0.6	1.1	-1.1	-0.1
Worry too long after embarrassment	0.4	0.7	0.9	0.8	0.9
Medication: Allopurinol	0.4	0.5	0.7	0.5	0.8
Medication: Omeprazole	0.4	0.5	0.6	-0.8	-0.5
Whole body fat mass	0.4	1.7	2.4	1.0	1.6
Overall health rating	0.4	0.9	1.3	0.6	1.1
Long-standing illness, disability or infirmity	0.4	0.7	0.9	0.7	0.9
Friendships satisfaction	0.4	0.4	0.7	-0.9	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.2	-0.3	-1.1
Breast cancer (self-reported)	0.4	0.5	0.6	-0.6	-0.8
Miserableness	0.4	0.7	0.7	0.8	0.9
Medication: Atorvastatin	0.4	0.5	0.8	0.9	0.5
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.4	1.2	0.5
Crohns Disease (2017)	0.3	0.7	0.9	-0.8	-0.9
Reaction Time	0.3	0.5	0.6	0.7	0.7
Age at First Birth	0.3	0.5	0.7	0.5	0.8
HbA1C	0.3	0.3	0.4	-0.5	-0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.6	-0.2	-0.8
Blood Platelet Count	0.3	3.0	3.0	-1.7	-1.7
Blood White Count	0.3	1.9	3.8	-1.9	-0.2
Smoking Status	0.3	0.7	1.0	0.7	1.0
Cardiovascular Disease	0.3	1.1	1.9	0.5	1.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.5	-0.7	-0.3
Pack years adult smoking proportion	0.3	0.5	0.9	-0.1	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	0.9	0.9	0.8
Trunk fat mass	0.3	1.4	2.1	0.9	1.4
Past tobacco smoking	0.3	0.6	0.9	-0.6	-0.9
Fluid intelligence score	0.3	0.7	1.3	1.1	0.3
Noisy workplace	0.3	0.3	0.6	-0.0	0.8
Illnesses of mother	0.3	0.3	0.4	-0.7	-0.5
Impedance of arm (left)	0.3	1.2	1.5	-1.0	-1.2
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.5	-0.7	-0.4
Body fat percentage	0.3	1.1	1.7	0.7	1.3
Leg fat percentage (right)	0.3	1.1	1.6	0.7	1.3
Wheeze or whistling in the chest in last year	0.3	0.6	0.6	-0.8	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.7	-0.8	-0.1
Angina (self-reported)	0.3	0.4	0.6	-0.8	-0.5
Leg fat mass (right)	0.3	1.2	1.8	0.7	1.4
Alcohol intake frequency.	0.3	0.6	1.3	-1.1	0.1
Average weekly champagne plus white wine intake	0.3	0.5	0.9	1.0	0.0
Mother’s age at death	0.3	0.3	0.6	0.1	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.5	0.5	0.7
Number of operations (self-reported)	0.3	0.4	0.7	0.8	0.4
Irritability	0.3	0.5	0.6	-0.6	-0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.5	0.5	0.7
Leg fat mass (left)	0.3	1.0	1.6	0.7	1.3
Arm predicted mass (left)	0.3	1.3	1.7	0.9	1.3
Depressed Affect (Nagel 2018)	0.2	0.4	0.6	0.8	0.5
Neuroticism (Nagel 2018)	0.2	0.5	0.6	0.7	0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.4	-0.3	0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	-0.7	-0.3
Crohns Disease (2012)	0.2	0.4	0.5	-0.6	-0.7
HDL Cholesterol	0.2	0.3	0.5	-0.7	-0.2
Systolic Blood Pressure	0.2	1.2	1.4	-1.0	-1.2
Allergy or Eczema	0.2	0.5	0.5	-0.7	-0.7
Hypothyroidism (self reported)	0.2	0.5	0.5	0.7	0.7
Respiratory disease	0.2	0.4	0.5	-0.5	-0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.3	0.5	0.5
Medication: Metformin	0.2	0.3	0.5	-0.2	-0.7
Leg fat-free mass (left)	0.2	1.2	1.7	0.8	1.3
Taking other prescription medications	0.2	0.4	0.4	0.6	0.7
High blood pressure (mother)	0.2	0.2	0.4	0.2	0.6
Body mass index (BMI)	0.2	1.0	1.5	0.7	1.2
Leg predicted mass (left)	0.2	1.1	1.5	0.8	1.2
Waist circumference	0.2	0.6	0.9	0.5	0.9
Had other major operations	0.2	0.2	0.3	0.6	0.4
Heart attack	0.2	0.2	0.4	0.2	0.6
Pain all over the body in last month	0.2	0.3	0.5	0.2	0.7
Weight	0.2	1.1	1.7	0.7	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.6	-0.8	0.0
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	0.4	0.7
Prospective memory result	0.2	0.2	0.4	0.6	0.3
Birth weight of first child	0.2	0.4	0.8	0.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	0.5	0.7
Age at first live birth	0.2	0.4	0.6	0.4	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	-0.6	-0.3
Family relationship satisfaction	0.2	0.2	0.4	-0.1	0.6
Diabetes diagnosed by doctor	0.2	0.3	0.5	-0.4	-0.7
Qualifications: nursing, teaching	0.2	0.2	0.4	0.6	0.4
Eye problems/disorders: Cataract	0.2	0.2	0.3	0.5	0.5
Mineral and other dietary supplements	0.2	0.3	0.5	0.3	-0.7
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	0.6	0.3
Whole body water mass	0.2	0.9	1.3	0.7	1.1
Arm fat mass (left)	0.2	1.0	1.4	0.7	1.2
Financial situation satisfaction	0.2	0.3	0.5	0.2	0.7
High cholesterol (Self-reported)	0.2	0.3	0.3	0.6	0.6
Basal metabolic rate	0.2	0.9	1.4	0.7	1.2
Ever depressed for a whole week	0.2	0.3	0.3	0.6	0.4
Pack years of smoking	0.2	0.3	0.5	-0.3	0.7
Impedance of whole body	0.2	1.0	1.3	-0.8	-1.2
Worry (Nagel 2018)	0.1	0.1	0.1	0.4	0.4
Breast Cancer	0.1	0.3	0.4	-0.6	0.4
Neuroticism (2016)	0.1	0.2	0.3	-0.6	-0.2
Blood Eosinophil Count	0.1	0.5	0.9	-0.9	-0.3
BMI	0.1	0.3	0.5	0.3	0.7
Waist Hip Ratio (WHR)	0.1	0.4	0.7	-0.5	-0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.5	-0.1
Lung FEV1/FVC ratio	0.1	0.5	1.0	-0.1	1.0
Hand grip strength (left)	0.1	0.4	0.5	0.7	0.5
Number of treatments/medications taken	0.1	0.1	0.2	-0.1	0.5
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.1	-0.2	0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	-0.4	-0.3
Supplements: Zinc	0.1	0.1	0.1	0.4	0.4
Maternal smoking around birth	0.1	0.1	0.3	0.5	0.0
Fed-up feelings	0.1	0.1	0.1	0.3	0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.5	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.2	0.5
High blood pressure	0.1	0.2	0.3	-0.6	-0.1
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.3	0.4
Impedance of leg (left)	0.1	0.5	0.7	-0.7	-0.8
Alcohol usually taken with meals	0.1	0.2	0.3	0.6	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	0.4	0.7
Trunk fat-free mass	0.1	0.3	0.5	0.3	0.7
Alcohol intake versus 10 years previously	0.1	0.2	0.4	-0.6	0.1
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	-0.4	0.2
Breastfed as a baby	0.1	0.1	0.2	0.5	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	-0.6	-0.1
Pulse wave reflection index	0.1	0.1	0.2	-0.2	-0.4
Headache pain in last month	0.1	0.2	0.4	0.0	0.6
Gout (self-reported)	0.1	0.1	0.2	0.1	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.1	-0.5
Qualifications: College or University degree	0.1	0.4	0.7	0.8	0.5
Emphysema/chronic bronchitis	0.1	0.1	0.2	-0.4	-0.1
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	-0.4	0.1
Mean time to correctly identify matches	0.1	0.2	0.3	0.4	0.5
Heart disease (mother)	0.1	0.1	0.1	-0.3	-0.4
Pulse rate, automated reading	0.1	0.2	0.4	-0.7	0.2
Comparative height size at age 10	0.1	0.7	1.1	0.6	1.1
Number of full sisters	0.1	0.2	0.2	0.5	0.3
Hypertension (Self-reported)	0.1	0.2	0.4	-0.6	-0.2
Smoking status: Previous	0.1	0.1	0.2	-0.1	0.5
Whole body fat-free mass	0.1	0.7	1.0	0.6	1.0
Leg fat-free mass (right)	0.1	0.7	0.9	0.6	0.9
Arm fat percentage (left)	0.1	0.5	0.7	0.5	0.8
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.2	0.5	0.3
Medication for cholesterol	0.1	0.2	0.4	0.6	-0.0
Osteoporosis (self-reported)	0.1	0.1	0.2	0.1	0.5
Leg predicted mass (right)	0.1	0.7	0.9	0.6	0.9
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.4	0.2
Commuting to job workplace: Public transport	0.1	0.1	0.1	0.2	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	-0.4	0.4
Alcohol drinker status: Never	0.1	0.1	0.1	-0.3	-0.4
Leg fat percentage (left)	0.1	0.5	0.9	0.4	0.9
Arm fat-free mass (left)	0.1	0.7	1.1	0.6	1.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.2	0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.4	0.2	0.6
Unable to work because of sickness or disability	0.1	0.1	0.1	0.4	-0.3
Triglycerides	0.0	0.0	0.0	0.0	-0.0
Blood Red Count	0.0	0.1	0.2	-0.0	-0.5
Heel T-Score	0.0	0.2	0.3	-0.4	0.5
Height	0.0	0.7	1.3	-0.1	1.2
Neuroticism	0.0	0.1	0.1	0.3	-0.2
Chronotype (morning person)	0.0	0.0	0.1	0.3	0.1
Hair Pigment	0.0	0.3	0.5	0.1	0.7
Tanning	0.0	0.1	0.1	0.2	-0.3
Relative age of first facial hair	0.0	0.1	0.1	-0.2	-0.4
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.1	-0.2
Systolic blood pressure, automated reading	0.0	0.1	0.2	-0.4	-0.3
Medication: Co-codamol	0.0	0.0	0.0	-0.2	0.1
Impedance of leg (right)	0.0	0.1	0.1	-0.3	-0.3
Hand grip strength (right)	0.0	0.0	0.1	-0.2	-0.1
Average weekly fortified wine intake	0.0	0.0	0.0	0.2	-0.2
Multivitamins +/- minerals	0.0	0.0	0.1	-0.3	0.1
Medication: Atenolol	0.0	0.0	0.0	-0.1	-0.2
Sitting height	0.0	0.1	0.2	0.4	0.2
Had menopause	0.0	0.0	0.0	0.0	-0.2
Qualifications: None of the above	0.0	0.0	0.0	-0.1	0.2
Illnesses of siblings	0.0	0.0	0.0	-0.1	-0.1
Neuroticism score	0.0	0.0	0.0	0.2	0.0
Impedance of arm (right)	0.0	0.0	0.0	-0.0	-0.2
Worrier / anxious feelings	0.0	0.0	0.0	0.2	0.1
Lung cancer (father)	0.0	0.0	0.1	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.0	-0.1	0.1
Trunk predicted mass	0.0	0.2	0.4	0.2	0.6
Standing height	0.0	0.0	0.1	-0.1	0.3
Birth weight	0.0	0.0	0.0	-0.2	-0.0
Forced vital capacity (FVC), Best measure	0.0	0.1	0.1	-0.3	0.2
Arm fat-free mass (right)	0.0	0.2	0.4	0.3	0.6
Arm predicted mass (right)	0.0	0.1	0.2	0.2	0.4
Suffer from ‘nerves’	0.0	0.0	0.1	-0.2	-0.1
Leg pain on walking	0.0	0.0	0.0	-0.0	0.0
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	0.1	0.2
Illnesses of father: Heart disease	0.0	0.1	0.1	-0.3	-0.1
Commuting to job workplace: Walk	0.0	0.0	0.0	0.2	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.2	-0.4	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.0	0.1	-0.1
Age started oral contraceptive pill	0.0	0.0	0.0	-0.2	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.1	0.2	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.1	-0.2

Hub : Genes

CXCL5

Models

Trait associations