TWAS hub - SEP15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0770	0.0210	9.5e-11	0.107	0.092	0.096	0.102	0.110	6.5e-13	2.8e-11	1.1e-11	2.4e-12	2.7e-13
2	GTEx	Adipose Visceral Omentum	0.2100	0.0750	3.1e-03	-0.004	NA	0.011	NA	0.009	5.7e-01	NA	8.6e-02	NA	1.1e-01
3	GTEx	Brain Caudate basal ganglia	0.1380	0.0690	6.2e-03	0.119	NA	0.046	NA	0.012	2.8e-04	NA	1.9e-02	NA	1.4e-01
4	GTEx	Brain Cerebellum	0.1380	0.0570	2.5e-03	0.149	NA	0.086	NA	0.097	3.7e-05	NA	1.7e-03	NA	8.3e-04
5	GTEx	Brain Cortex	0.1950	0.0730	1.8e-03	0.138	NA	0.159	NA	0.162	1.2e-04	NA	3.8e-05	NA	3.1e-05
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1450	0.0720	9.1e-03	0.070	NA	0.057	NA	0.091	6.1e-03	NA	1.2e-02	NA	2.0e-03
7	GTEx	Brain Putamen basal ganglia	0.2720	0.1080	4.7e-03	-0.012	NA	0.011	NA	0.000	8.1e-01	NA	1.7e-01	NA	3.2e-01
8	GTEx	Cells EBV-transformed lymphocytes	0.2960	0.0870	2.3e-04	0.174	NA	0.048	NA	0.131	2.6e-06	NA	1.1e-02	NA	5.0e-05
9	GTEx	Nerve Tibial	0.0781	0.0320	4.7e-04	0.023	NA	0.022	NA	0.015	8.7e-03	NA	1.0e-02	NA	2.7e-02
10	GTEx	Testis	0.1690	0.0760	2.5e-03	-0.005	NA	-0.004	NA	-0.006	6.0e-01	NA	5.3e-01	NA	8.4e-01
11	METSIM	Adipose	0.0387	0.0161	2.1e-04	0.025	0.018	0.019	0.018	0.015	8.6e-05	8.7e-04	5.3e-04	7.3e-04	2.0e-03
12	ROSMAP	Brain Pre-frontal Cortex	0.1444	0.0302	0.0e+00	0.233	0.222	0.250	0.235	0.243	1.6e-29	5.3e-28	8.2e-32	8.3e-30	6.7e-31
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0581	0.0316	3.8e-04	0.031	0.014	0.026	NA	0.022	1.6e-04	9.3e-03	5.3e-04	NA	1.4e-03
14	TCGA	Brain Lower Grade Glioma	0.0360	0.0182	4.2e-07	0.061	0.061	0.061	NA	0.056	1.8e-07	1.6e-07	1.6e-07	NA	5.6e-07
15	TCGA	Thyroid Carcinoma	0.0230	0.0160	6.7e-03	0.019	0.025	0.031	NA	0.028	5.3e-03	1.7e-03	4.8e-04	NA	8.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Hearing difficulty/problems with background noise	6.2	9.9	18.9	-4.1	-3.5	-2.2	-4.2	-2.2	-3.6	-0.6	2.9	-2.7	-2.1	-4.3	-3.9	-1.4	-3.9	-2.9
Pulse rate	5.7	9.7	18.1	3.6	0.8	4.3	3.5	2.6	2.6	3.3	0.9	3.2	3.6	3.6	4.1	2.4	2.6	3.3
Illnesses of mother	4.1	5.1	10.0	2.8	2.0	2.4	2.4	2.3	2.5	1.1	-0.7	3.2	1.6	2.6	2.5	1.6	2.5	2.3
Ever had bowel cancer screening	4.1	4.8	8.8	-2.8	-1.4	-1.0	-2.4	-0.5	-3.0	0.0	1.2	-2.0	-2.5	-2.4	-2.5	-2.7	-2.6	-2.9
Bipolar Disorder (2011)	3.9	3.8	8.9	-2.4	-1.1	-0.6	-2.2	-1.1	-2.3	0.3	-0.7	-0.7	-3.0	-2.0	-2.0	-3.0	-1.8	-2.8
Hearing difficulty/problems: Yes	3.9	5.9	15.8	-2.9	-4.0	-1.2	-2.5	-0.5	-2.8	-0.2	1.7	-3.1	-1.1	-2.7	-2.6	-2.4	-2.8	-2.7
Neuroticism (Nagel 2018)	3.7	8.6	29.4	-3.1	-0.9	-5.4	-3.5	-2.9	-3.0	-1.8	0.8	-2.6	-3.4	-3.7	-3.7	-0.1	-2.8	-1.7
Forced vital capacity (FVC)	3.7	14.3	26.5	-4.7	-0.9	-2.8	-4.4	-3.3	-4.7	-1.3	3.1	-2.1	-4.7	-4.8	-4.5	-2.7	-5.2	-4.0
Neck or shoulder pain in last month	3.7	5.3	9.6	-2.8	-2.8	-1.9	-2.7	-0.4	-2.1	-1.1	-0.3	-2.0	-3.1	-2.6	-2.5	-2.8	-1.8	-3.0
Reaction Time	3.5	6.6	12.0	-3.1	-1.9	-3.5	-2.9	-1.6	-2.6	-0.9	2.1	-2.5	-3.0	-3.0	-3.1	-1.8	-2.9	-2.4
Suffer from ‘nerves’	3.5	5.4	13.7	-2.5	0.9	-3.7	-2.7	-3.0	-2.4	-1.4	0.6	-0.7	-3.3	-3.0	-3.0	0.1	-2.3	-1.3
Medication: Gliclazide	3.5	3.9	10.4	-2.5	1.1	-1.3	-2.3	-1.5	-2.5	-0.9	0.1	-1.1	-3.2	-2.4	-2.3	-1.7	-2.1	-2.2
Neuroticism	3.3	8.0	26.5	-3.1	-0.4	-5.2	-3.4	-2.6	-2.9	-1.8	0.7	-2.7	-3.3	-3.4	-3.5	-0.6	-2.6	-1.9
Maternal smoking around birth	3.2	4.6	8.5	-2.4	-2.8	-2.9	-2.2	-0.4	-2.2	-1.3	0.5	-2.9	-0.7	-2.4	-2.5	-2.0	-2.1	-2.5
Pulse wave reflection index	3.2	3.9	11.2	-2.2	-0.7	-2.8	-1.8	-1.9	-1.6	-2.0	-0.9	-3.3	-1.3	-2.2	-2.1	-1.6	-1.6	-2.2
Depressed Affect (Nagel 2018)	3.1	6.6	27.1	-2.7	-1.3	-5.2	-2.5	-2.2	-2.6	-1.5	0.6	-3.0	-2.6	-2.7	-3.1	-1.0	-2.3	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.1	3.7	6.2	-2.2	-1.1	-2.3	-2.5	-2.1	-2.3	-0.9	0.5	-2.0	-1.7	-2.3	-2.3	-1.2	-2.1	-1.9
High blood pressure	3.0	8.3	14.5	-3.3	-1.1	-3.5	-3.5	-2.6	-3.3	-0.9	2.1	-2.5	-3.7	-3.8	-3.8	-0.4	-3.3	-2.0
Lung FVC	2.9	14.9	27.0	-4.9	-1.7	-3.6	-4.5	-3.0	-5.1	-0.7	2.8	-2.6	-3.8	-4.9	-4.4	-3.2	-5.2	-4.3
Fractured/broken bones in last 5 years	2.9	3.7	7.7	2.3	0.9	1.9	2.7	2.7	2.0	1.6	-1.3	0.9	1.4	2.8	2.3	-0.3	2.4	1.1
Medication for hormone replacement therapy	2.8	3.1	9.3	-1.7	-1.2	-3.0	-1.7	-0.5	-2.2	-1.7	2.0	-1.6	-1.3	-1.8	-2.0	-1.0	-1.9	-1.4
Current tobacco smoking	2.8	4.5	8.9	2.6	1.3	1.9	2.7	0.6	2.4	1.2	0.0	1.6	2.5	2.7	2.4	2.4	2.3	3.0
Forced expiratory volume in 1-second (FEV1)	2.8	9.3	16.1	-3.8	-1.3	-2.6	-3.4	-2.5	-3.8	-1.2	2.5	-2.2	-3.6	-3.7	-3.5	-2.4	-4.0	-3.4
Birth weight	2.8	6.0	13.5	-3.0	-3.7	-1.7	-3.0	-0.7	-2.4	-1.9	0.0	-2.6	-2.5	-3.0	-2.8	-2.0	-2.3	-2.6
Medication: Aspirin	2.8	3.7	7.5	-2.2	-0.3	-2.2	-2.7	-2.0	-1.6	-1.7	1.4	-1.9	-2.2	-2.7	-2.3	0.8	-2.1	-0.6
Osteoporosis (self-reported)	2.8	3.5	9.5	2.1	-0.2	1.9	1.9	1.9	1.9	0.7	-0.2	1.1	3.1	2.3	2.4	1.3	2.1	2.2
Illnesses of father: High blood pressure	2.8	3.5	6.7	-2.3	0.6	-2.1	-2.6	-1.4	-2.4	-0.5	0.4	-1.3	-2.1	-2.4	-1.9	-1.6	-2.2	-2.1
Supplements: Zinc	2.7	2.9	7.9	-2.0	0.8	0.1	-2.0	-2.8	-1.9	-0.6	1.0	-2.2	-2.0	-2.1	-2.1	-0.2	-1.9	-1.0
Stomach or abdominal pain in last month	2.7	3.3	12.5	-2.0	0.3	-1.0	-2.0	-1.5	-2.4	0.7	1.7	0.1	-3.5	-2.2	-2.0	-1.1	-2.2	-1.6
Number of live births	2.7	3.8	11.7	-1.9	-0.6	-3.4	-2.0	-0.3	-2.5	-2.7	2.1	-1.1	-0.9	-2.0	-2.1	-1.1	-2.2	-1.6
Mean time to correctly identify matches	2.7	5.1	7.8	-2.8	-1.9	-2.4	-2.4	-1.1	-2.3	-1.3	1.8	-2.1	-2.5	-2.6	-2.5	-2.3	-2.6	-2.5
Pulse rate, automated reading	2.7	8.8	14.8	3.8	1.0	3.2	3.6	1.8	3.2	2.8	0.2	2.2	3.0	3.6	3.3	3.0	3.2	3.9
Schizophrenia vs Biploar Disorder	2.6	3.4	7.5	2.4	0.2	0.5	2.0	1.8	2.7	0.0	0.8	1.5	1.8	2.0	1.8	2.3	2.3	2.5
Fed-up feelings	2.6	4.7	21.2	-2.2	-1.9	-4.6	-2.1	-1.2	-1.9	-1.3	0.5	-1.8	-2.4	-2.0	-2.9	-1.2	-1.7	-1.9
Peak expiratory flow (PEF)	2.6	6.1	9.9	-3.1	-3.0	-1.8	-2.5	-1.8	-2.8	-1.5	1.6	-2.4	-1.4	-2.8	-2.9	-2.2	-3.1	-3.0
Forced vital capacity (FVC), Best measure	2.6	9.4	17.2	-3.9	-0.5	-2.2	-3.5	-2.8	-3.8	-1.3	2.6	-2.1	-3.5	-3.7	-3.5	-2.6	-4.2	-3.4
Medication: Allopurinol	2.6	3.5	6.5	-2.2	-2.2	-2.5	-2.1	-1.4	-1.7	-0.9	0.9	-1.9	-2.2	-2.4	-2.0	-1.1	-1.7	-1.8
Hypertension (Self-reported)	2.6	7.2	12.7	-3.2	-1.2	-3.2	-3.4	-2.2	-3.2	-0.8	1.9	-2.1	-3.5	-3.6	-3.5	-0.5	-3.2	-1.9
Osteoarthritis (self-reported)	2.6	3.4	7.1	2.1	-0.2	1.8	2.7	2.4	2.2	1.0	-0.9	-0.3	2.6	2.6	1.8	0.1	2.2	1.3
Worrier / anxious feelings	2.5	4.6	10.1	-2.4	0.1	-2.6	-2.9	-2.5	-2.5	-0.5	-0.2	-0.9	-3.2	-2.8	-3.0	-0.3	-2.2	-1.7
Medication for pain relief, constipation, heartburn	2.5	4.2	9.2	2.3	0.7	2.4	3.0	1.8	1.8	0.2	-2.7	1.2	2.3	2.9	2.6	-0.3	2.5	1.0
Medication: Lisinopril	2.5	3.3	6.6	-2.3	-0.4	-1.0	-2.6	-2.0	-1.8	-1.4	1.0	-1.9	-2.0	-2.6	-2.0	-0.7	-2.3	-1.5
Ever had prostate specific antigen (PSA) test	2.5	2.9	5.1	-2.1	-1.7	-2.2	-2.2	-1.8	-1.6	-1.3	0.2	-1.5	-1.6	-2.2	-2.2	-0.5	-1.6	-1.3
HbA1C	2.4	2.7	5.6	-2.1	1.1	-1.7	-1.6	-0.3	-2.0	-1.4	0.7	-1.1	-2.4	-1.9	-1.6	-1.4	-2.0	-1.9
Gout (self-reported)	2.4	3.3	8.3	-1.9	-2.6	-2.6	-1.9	-1.2	-1.7	-1.2	0.8	-1.5	-2.9	-2.1	-1.5	-0.9	-1.5	-1.5
Bipolar Disorder (2018)	2.3	3.7	8.3	-2.4	-0.9	-1.9	-2.1	-1.9	-2.9	-1.3	0.5	-1.5	-1.9	-2.0	-2.1	-1.7	-2.4	-2.1
Heart disease (mother)	2.3	2.8	4.9	-2.1	-1.8	-2.2	-1.8	-0.8	-1.9	0.2	1.1	-1.5	-1.4	-2.0	-1.9	-1.4	-1.8	-2.0
Vascular/heart problems diagnosed by doctor	2.3	6.3	11.8	2.7	0.3	3.4	3.2	2.3	2.8	1.1	-1.6	2.1	3.4	3.4	3.4	-0.1	2.8	1.4
Average weekly fortified wine intake	2.2	2.6	8.0	1.7	2.8	1.1	0.9	0.7	1.6	2.2	-1.0	1.6	-0.3	1.1	1.7	2.1	1.7	2.1
Average weekly red wine intake	2.2	3.3	10.7	-1.9	0.5	-1.6	-1.8	-0.6	-1.6	-1.7	-0.3	-3.3	-2.2	-1.6	-2.2	-2.1	-1.3	-2.1
Verbal and Numeric Reasoning (VNR)	2.1	5.0	12.5	2.3	1.3	2.8	2.3	1.1	3.1	2.1	-3.5	1.7	2.0	2.2	2.3	0.9	2.6	1.5
Number of treatments/medications taken	2.1	3.7	10.0	-2.4	-0.9	-2.4	-3.2	-1.5	-1.6	-0.4	1.4	-1.1	-2.3	-2.9	-2.6	-0.1	-2.0	-1.1
Smoking status: Current	2.1	3.3	5.8	2.2	0.7	1.5	2.4	0.5	2.2	1.1	-0.4	1.1	2.4	2.3	2.0	1.9	2.1	2.4
Ever had hysterectomy (womb removed)	2.0	2.3	6.0	-1.3	-0.5	-1.1	-1.8	-1.3	-1.7	0.3	2.5	-0.5	-1.8	-2.0	-2.2	1.0	-1.8	-0.3
Hayfever, allergic rhinitis or eczema	2.0	4.3	8.6	-2.3	0.3	-2.5	-2.6	-2.4	-2.2	-2.3	0.3	-0.7	-2.9	-2.4	-2.9	-0.8	-1.9	-1.5
Lung cancer (father)	2.0	2.3	4.9	-2.0	-1.4	-0.2	-1.4	-0.8	-1.8	0.4	1.6	-1.2	-0.4	-1.7	-2.0	-1.5	-2.2	-1.9
Medication: Seretide 50 evohaler	2.0	2.3	4.1	-1.8	-0.2	-1.3	-1.6	-1.2	-1.9	-0.1	0.9	-1.9	-2.0	-1.6	-1.8	-1.5	-1.6	-1.7
Heart disease (siblings)	2.0	2.5	7.3	1.4	-1.5	1.1	1.5	2.2	1.4	2.7	-0.2	1.3	2.6	1.6	1.3	0.1	1.5	0.7
Emphysema/chronic bronchitis	1.9	2.1	4.5	-1.5	-2.1	-1.5	-1.9	-0.7	-1.9	-1.2	0.5	-1.1	-0.6	-1.6	-1.5	-1.4	-1.5	-1.6
Pack years of smoking	1.9	2.9	7.2	2.0	1.3	1.4	2.3	1.9	1.3	0.6	-1.1	0.3	2.7	2.1	2.2	1.1	1.7	1.7
Allergy or Eczema	1.8	4.9	8.8	-2.5	-0.4	-2.8	-2.7	-2.6	-2.4	-2.4	0.5	-1.1	-3.0	-2.6	-2.9	-0.8	-2.2	-1.6
Sensitivity / hurt feelings	1.8	3.1	15.3	-1.4	0.1	-3.9	-2.1	-1.4	-1.6	-1.6	0.8	-1.6	-1.9	-2.0	-2.0	0.7	-1.6	-0.5
Pack years adult smoking proportion	1.8	2.7	5.8	1.9	1.5	1.5	2.2	1.7	1.2	0.7	-0.9	0.3	2.4	2.0	2.1	1.2	1.5	1.8
Pain all over the body in last month	1.8	1.9	8.7	0.9	0.9	0.1	0.9	0.8	2.0	-1.7	-3.0	0.1	2.0	1.0	1.0	0.4	1.9	0.9
Fluid intelligence score	1.8	3.7	6.9	2.1	1.4	1.5	1.7	0.5	2.5	1.7	-2.6	2.1	1.3	1.9	2.3	1.6	2.3	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.7	10.2	-3.0	-0.9	-2.1	-2.6	-2.0	-3.0	-1.1	2.3	-1.8	-2.4	-2.7	-2.5	-2.2	-3.2	-2.8
Knee pain experienced in last month	1.8	2.8	8.5	-1.8	-2.9	-2.4	-1.4	0.2	-1.7	-0.4	1.7	-1.7	-1.0	-1.4	-1.8	-1.6	-1.4	-1.8
Basal cell carcinoma (self-reported)	1.8	2.1	4.0	1.6	-0.4	1.7	2.0	1.7	1.5	1.5	-1.2	0.9	2.0	1.6	1.7	0.3	1.6	0.9
Intelligence (Savage-Jansen 2018)	1.7	5.1	14.1	2.4	0.0	2.7	2.4	0.8	3.4	1.4	-3.8	1.2	2.4	2.2	2.1	1.2	2.8	1.7
Mean Putamen Volume	1.7	1.9	3.7	-1.6	-1.9	-1.1	-0.8	-1.1	-1.9	-0.4	-0.1	-1.7	-0.3	-1.3	-1.6	-1.5	-1.6	-1.8
Lung FEV1/FVC ratio	1.7	8.6	15.2	3.7	-0.4	1.8	3.6	2.4	3.7	1.2	-1.5	2.3	3.6	3.9	3.8	2.1	3.8	3.0
Multivitamins +/- minerals	1.7	2.2	5.0	-1.7	0.3	-1.0	-1.5	-1.3	-1.2	-2.2	0.4	-1.6	-1.3	-1.4	-1.9	-1.6	-1.4	-1.8
High blood pressure (mother)	1.7	2.4	5.0	-2.1	-1.6	-1.5	-2.2	-1.8	-1.3	-0.8	-0.6	-1.4	-1.1	-2.2	-1.6	-0.9	-1.4	-1.4
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	3.7	-1.6	-1.8	-1.2	-1.5	0.1	-1.2	-1.4	1.8	-1.9	-1.6	-1.3	-1.3	-1.6	-1.3	-1.4
Smoking status: Previous	1.7	2.6	6.4	-1.7	-0.6	-2.2	-2.5	-2.5	-1.7	-0.9	0.2	-1.4	-1.4	-2.1	-1.8	0.2	-1.5	-0.8
Guilty feelings	1.7	2.5	7.8	-1.6	0.2	-2.3	-2.1	-1.1	-1.5	-0.9	0.8	-0.8	-2.8	-2.0	-2.2	0.4	-1.6	-0.8
Average weekly beer plus cider intake	1.7	2.4	5.0	1.5	-0.7	1.6	1.9	0.9	1.7	1.9	-1.1	1.6	2.2	1.9	1.7	0.3	2.0	1.1
Ever used hormone-replacement therapy (HRT)	1.6	2.1	6.6	-1.4	-0.9	-2.1	-1.5	0.4	-1.4	-2.6	1.5	-1.7	-0.4	-1.3	-1.5	-0.9	-1.2	-1.0
Loud music exposure frequency	1.6	1.8	6.1	-1.1	-1.6	-2.5	-1.5	-1.8	-1.2	0.6	1.8	-0.7	-1.6	-1.1	-0.5	-0.2	-1.3	-0.7
Mood swings	1.6	3.0	10.2	-1.9	-1.4	-3.2	-1.6	-1.5	-1.8	-0.1	0.4	-2.0	-1.0	-1.8	-1.9	-1.4	-1.8	-1.9
High cholesterol (Self-reported)	1.6	2.8	8.2	-1.4	-2.1	-2.9	-1.6	-1.1	-1.2	-2.1	2.0	-1.2	-1.2	-1.8	-1.9	0.7	-1.6	-0.4
Alzheimer’s Disease (in mother)	1.5	1.8	4.2	1.2	0.6	2.0	1.7	0.9	1.8	1.4	-1.4	-0.3	1.7	1.8	1.1	-0.3	1.5	0.4
Major Depression (MDD)	1.5	1.9	5.7	-1.5	0.5	0.4	-1.8	-1.7	-1.6	1.8	0.1	-0.4	-2.4	-1.5	-1.1	-0.7	-1.5	-1.0
Had other major operations	1.5	1.8	3.9	-1.3	-0.7	-1.4	-1.4	-1.2	-1.4	-2.0	-1.2	-1.3	-0.9	-1.3	-1.2	-1.6	-1.1	-1.6
Alcohol intake versus 10 years previously	1.5	2.3	5.9	1.7	0.6	2.0	2.0	1.5	1.3	1.8	0.0	0.5	2.4	1.8	1.7	0.5	1.6	1.2
Chest pain or discomfort	1.5	2.1	5.4	1.4	-0.2	-0.4	1.4	2.1	1.9	0.5	-2.3	1.5	0.5	1.8	1.5	-0.1	2.3	0.9
Medication: Aspirin	1.5	1.9	4.8	-1.5	-0.2	-1.4	-2.2	-1.3	-0.9	-1.2	1.1	-1.2	-1.6	-2.1	-1.6	1.0	-1.4	-0.1
Supplements: Calcium	1.5	1.7	5.3	-1.3	-1.9	0.7	-0.9	0.3	-0.9	1.3	-0.2	-2.3	0.0	-0.8	-1.3	-2.1	-1.0	-1.6
Allergy	1.4	3.3	6.8	2.0	0.5	2.2	2.3	2.1	2.2	1.4	-0.3	0.2	2.4	2.1	2.6	0.7	1.9	1.4
Neuroticism score	1.4	2.8	14.1	-1.4	0.9	-3.8	-2.0	-1.9	-1.4	-1.2	-0.2	-0.9	-2.1	-1.9	-1.9	1.0	-1.1	-0.2
Leg pain on walking	1.4	1.7	6.6	1.4	-1.0	0.6	1.4	2.6	1.4	-0.0	-0.4	-0.2	1.7	1.7	1.5	-0.5	1.6	0.8
Medication for cholesterol	1.4	2.2	9.1	1.2	0.2	3.0	1.3	0.8	1.3	1.2	-2.4	0.4	2.0	1.4	1.4	-0.3	1.4	0.5
Worry (Nagel 2018)	1.3	2.7	9.4	-1.6	0.4	-3.1	-2.0	-2.6	-1.3	-0.6	-0.6	-0.7	-1.9	-2.1	-2.0	1.0	-1.0	-0.1
Chronotype (morning person)	1.3	3.1	6.8	2.3	0.9	1.4	1.9	2.6	1.3	0.2	-1.0	2.5	2.4	2.0	1.9	1.0	1.7	1.3
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	5.5	1.8	1.2	1.3	2.2	1.6	1.5	-0.6	-0.5	0.6	1.4	2.3	2.1	-0.5	1.6	0.7
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	4.9	-1.5	-1.8	-0.9	-2.2	-1.5	-1.6	0.2	0.9	-0.2	-1.7	-2.2	-1.7	0.2	-1.5	-0.6
Number of self-reported non-cancer illnesses	1.3	2.3	4.6	-1.6	-1.0	-2.1	-1.9	-1.0	-1.5	-1.2	1.6	-1.2	-1.6	-1.9	-1.9	0.1	-1.9	-0.7
Pain experienced in last month	1.3	2.2	3.7	1.5	1.6	1.8	1.7	-0.7	1.8	-0.8	-0.6	1.0	1.9	1.6	1.5	1.8	1.2	1.8
Diabetes (mother)	1.2	1.6	5.3	-1.4	0.9	-1.3	-1.3	-1.6	-0.8	-0.1	-0.5	-2.3	-1.0	-0.9	-1.1	-1.8	-0.8	-1.4
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.4	-1.1	-1.8	-0.9	-1.3	-0.4	-1.5	-0.3	-0.1	-0.6	-1.3	-1.3	-1.7	-0.8	-1.1	-1.2
Qualifications: None of the above	1.2	2.6	5.5	-1.9	-0.4	-1.6	-1.8	-1.3	-2.3	-0.1	0.7	-1.2	-1.0	-2.0	-2.0	-1.5	-2.2	-1.9
Illnesses of siblings	1.2	1.6	5.8	-1.2	-0.8	-1.2	-0.9	-1.2	-1.2	-1.9	-0.8	-2.4	-1.0	-0.7	-1.0	-1.5	-0.8	-1.4
Medication: Blood pressure	1.2	2.1	5.7	-1.8	-0.9	-1.0	-2.4	-1.5	-1.8	0.6	0.6	-0.7	-1.3	-2.3	-1.8	0.2	-1.7	-0.9
Medication: Bendroflumethiazide	1.2	1.9	3.7	-1.7	-0.9	-1.1	-1.6	-0.7	-1.3	-1.0	-0.7	-0.2	-1.9	-1.5	-1.6	-1.8	-1.3	-1.9
Medication: Atorvastatin	1.2	1.5	4.1	-1.7	-1.5	-0.9	-1.7	-0.4	-1.3	-0.3	0.5	-1.1	-0.4	-2.0	-1.2	-0.7	-1.3	-1.2
Ulcerative Colitis (UC)	1.1	2.1	7.3	-1.6	0.9	-2.1	-2.0	-0.8	-1.4	0.5	-0.0	-0.5	-2.7	-1.6	-1.1	-1.1	-1.4	-1.3
Hand grip strength (left)	1.1	3.0	5.2	-2.0	-2.1	0.3	-1.7	-1.1	-1.9	1.9	1.6	-2.0	-1.0	-1.8	-1.7	-1.4	-2.3	-2.1
Medication: Paracetamol	1.1	1.7	4.6	-1.4	0.4	-1.4	-1.7	-2.1	-1.0	1.0	0.5	0.0	-2.1	-1.7	-1.6	0.4	-1.3	-0.6
Eye problems/disorders: None of the above	1.1	1.3	2.5	-1.4	-0.2	-1.1	-1.2	-1.3	-1.3	1.4	0.7	-0.9	-0.9	-1.2	-1.6	-0.7	-1.3	-1.2
Breast cancer (self-reported)	1.1	1.3	2.4	-1.3	-0.5	0.4	-1.3	-1.5	-1.1	-0.4	-0.0	-0.7	-1.5	-1.1	-1.4	-1.4	-1.4	-1.5
Depression (Nagel 2018)	1.0	1.6	5.1	-1.3	-0.8	-2.2	-1.8	-1.5	-1.1	-0.8	0.8	-0.4	-0.9	-1.5	-1.6	0.9	-1.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.7	-1.0	-0.6	-1.9	-1.6	-1.4	-1.2	-0.9	1.1	-0.3	-1.1	-1.2	-1.5	0.4	-1.2	-0.2
Hair/balding pattern: Pattern 3	1.0	1.5	8.3	-0.9	-2.9	-1.3	-0.9	-1.2	-0.2	-0.4	2.5	-0.7	-0.5	-0.7	-0.7	0.3	-0.9	-0.4
Medication: Lansoprazole	1.0	1.2	3.0	-1.2	-0.5	-0.7	-0.8	-1.0	-1.0	-1.7	-0.4	-1.6	-0.3	-0.6	-1.1	-1.7	-0.7	-1.6
Blood clot in the leg (DVT)	1.0	1.3	3.0	-1.1	-0.8	-0.3	-1.2	-1.3	-1.2	-0.1	1.7	0.6	-1.1	-1.5	-1.4	1.1	-1.6	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	2.6	1.4	-0.3	-0.1	1.3	1.1	1.2	1.2	-0.6	1.4	1.0	1.0	1.4	1.2	1.6	1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	4.8	-1.5	0.7	-1.1	-1.5	-0.6	-1.6	-2.2	0.3	-1.6	-1.7	-1.3	-1.6	-1.5	-1.5	-1.6
Prostate Cancer	0.9	1.3	4.1	1.2	1.5	1.0	0.6	0.1	1.1	0.8	-0.6	1.1	0.8	0.7	1.0	2.0	1.1	1.8
Type 2 Diabetes (T2D) (2012)	0.9	1.0	3.1	0.7	-0.4	-0.8	0.8	1.4	0.6	1.0	-1.5	-0.0	1.8	1.1	1.2	-1.0	1.2	-0.1
Frequency of depressed mood in last 2 weeks	0.9	1.2	4.8	-0.5	0.5	-2.2	-1.2	-1.6	-0.0	-1.4	0.6	0.5	-1.1	-1.0	-0.9	1.7	-0.5	0.8
Systolic blood pressure, automated reading	0.9	2.6	5.3	2.0	0.7	2.0	2.3	2.2	1.5	0.8	-0.7	1.7	1.6	2.0	1.7	0.6	1.6	1.4
Medication: Co-codamol	0.9	1.1	3.1	-1.0	-0.8	-1.8	-0.9	1.2	-1.2	0.0	0.5	-0.5	0.3	-1.0	-0.9	-1.6	-1.0	-1.4
Hand grip strength (right)	0.9	2.4	6.4	-1.7	-0.4	1.3	-1.6	-1.9	-1.6	2.5	1.6	-0.6	-1.3	-1.8	-1.4	-0.1	-2.2	-1.2
Chronic bronchitis/emphysema (father)	0.9	1.0	3.2	-0.8	-0.1	-0.5	-0.2	0.4	-1.0	-1.5	-0.8	-1.8	-0.3	-0.6	-1.5	-1.3	-0.7	-1.6
Financial difficulties in last 2 years	0.9	1.2	4.3	-0.9	0.8	-0.9	-1.4	-0.8	-1.0	-2.1	0.1	-0.7	-1.9	-1.2	-1.1	0.4	-1.1	-0.3
Medication: Cholesterol lowering	0.9	1.4	3.5	-1.5	-1.8	-1.0	-1.6	-1.4	-1.0	-0.2	0.6	-0.6	-0.8	-1.9	-1.3	0.2	-1.3	-0.6
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.4	-1.1	0.5	-0.8	-0.9	-1.1	-1.3	-0.6	-1.3	-0.5	-1.5	-0.9	-0.7	-1.6	-0.8	-1.4
Medication: Ibuprofen	0.9	1.1	4.0	-0.9	-1.4	-0.5	-1.2	0.2	-0.5	-1.0	2.0	-1.1	-2.0	-0.8	-0.9	-0.4	-0.7	-0.5
Age at last live birth	0.9	1.3	4.1	-1.4	0.1	-1.7	-0.9	-1.1	-1.1	0.5	-0.1	-0.1	-0.8	-0.9	-0.7	-2.0	-1.0	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	3.0	-1.0	-0.8	-1.3	-1.2	-1.0	-1.1	-0.5	1.7	-0.5	-0.5	-1.1	-0.8	-0.1	-1.1	-0.3
Pain type(s) experienced in last month: Hip pain	0.9	1.2	5.3	-1.2	-0.7	-1.3	-0.9	0.5	-1.2	0.1	-0.5	-1.3	-0.4	-0.6	-0.7	-2.3	-0.4	-1.7
Diastolic blood pressure, automated reading	0.9	2.8	4.9	2.2	0.8	1.4	2.2	2.0	1.6	1.9	0.1	1.1	1.7	2.0	1.5	1.6	1.6	2.0
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	2.9	-1.0	-0.7	-0.2	-1.1	-1.4	-1.1	0.1	1.7	0.5	-1.1	-1.4	-1.3	1.1	-1.5	-0.0
Rheumatoid Arthritis	0.8	1.1	4.2	1.1	0.3	-0.7	1.1	1.4	1.0	-0.1	-2.1	0.1	0.8	1.6	0.9	-0.8	1.5	0.2
Vitamin and mineral supplements	0.8	1.2	3.9	1.3	-0.4	0.3	0.9	1.4	0.9	2.0	-0.1	1.0	0.6	1.0	1.3	1.2	1.0	1.2
Medication: Metformin	0.8	1.1	2.5	-1.3	-0.2	-1.6	-0.9	-0.8	-1.3	-0.1	0.8	-1.0	-1.2	-1.2	-0.9	-0.8	-1.3	-1.2
Serious illness, injury or assault to yourself	0.8	0.9	2.2	-0.9	1.2	-0.5	-0.8	0.4	-0.7	-1.0	-1.1	-1.1	-0.9	-0.7	-0.8	-1.5	-0.6	-1.4
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.0	-1.3	0.3	-0.4	-1.4	-1.4	-1.1	1.3	-0.1	-0.9	-0.8	-1.1	-1.0	-0.6	-0.9	-1.1
Number of incorrect matches in round	0.8	1.4	4.0	-1.3	-1.6	-0.3	-1.0	0.0	-1.1	-1.2	-0.8	-0.3	-0.2	-1.3	-1.2	-2.0	-1.2	-1.9
Heart attack	0.8	1.0	5.9	0.9	1.4	-0.2	0.1	-0.0	0.9	-0.5	1.0	0.2	0.4	0.2	0.8	2.4	0.5	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.5	1.3	1.1	-0.5	1.0	0.4	1.5	0.6	-0.4	1.3	0.4	1.0	0.6	2.1	1.3	1.9
Happiness	0.8	0.9	2.3	1.3	0.4	0.6	0.8	0.6	1.2	0.6	-1.2	1.5	-0.6	1.3	1.0	0.5	1.1	0.7
Medication: Amlodipine	0.8	1.1	2.8	-1.2	-0.7	-0.4	-0.9	-0.5	-1.1	-1.7	-0.6	-1.4	-0.2	-1.1	-1.1	-1.1	-0.8	-1.4
Arm fat-free mass (right)	0.8	4.1	8.1	-2.1	-0.1	-2.0	-2.6	-1.2	-2.6	-1.1	2.6	-2.5	-0.8	-2.5	-2.3	-0.7	-2.8	-1.6
Arm predicted mass (right)	0.8	3.9	7.8	-2.0	-0.1	-1.9	-2.4	-1.1	-2.6	-1.1	2.7	-2.5	-0.6	-2.4	-2.1	-0.7	-2.8	-1.6
Miserableness	0.8	1.4	8.5	-0.9	0.4	-2.9	-1.1	-1.4	-1.1	0.2	0.1	-0.3	-1.3	-1.1	-1.4	0.9	-0.8	0.1
Financial situation satisfaction	0.8	1.0	2.2	-0.8	-1.0	-0.9	-1.5	-1.1	-0.8	-0.3	1.0	-1.3	-1.2	-1.2	-1.0	0.8	-1.1	-0.1
Alcohol drinker status: Never	0.8	1.0	5.1	0.4	-0.3	2.3	0.7	1.8	0.3	1.7	-1.2	0.4	0.1	0.4	0.7	-0.6	0.4	-0.2
Number of operations (self-reported)	0.8	1.1	3.1	-0.9	-0.7	-1.7	-1.1	-0.3	-1.1	-1.8	1.3	-1.3	-0.1	-0.9	-0.8	-0.8	-0.9	-1.0
Age started oral contraceptive pill	0.8	1.0	4.6	1.1	0.5	0.7	1.3	2.1	0.4	0.4	-0.3	1.2	0.5	1.1	1.4	-0.5	0.9	0.1
Ever depressed for a whole week	0.8	1.0	2.9	-0.9	1.7	-0.5	-0.9	-1.1	-1.2	-0.4	1.4	-0.5	-1.3	-0.9	-0.7	-0.2	-1.4	-0.6
Ovarian Cancer	0.7	0.9	2.9	-1.0	-0.7	-1.4	-0.9	-0.6	-0.6	-1.7	-0.0	-0.2	-1.5	-1.0	-1.0	-0.8	-0.7	-0.9
Ulcerative Colitis	0.7	1.1	4.2	-1.1	1.1	-1.7	-1.4	-0.7	-0.8	0.7	0.3	0.4	-2.0	-0.9	-0.3	-0.8	-1.0	-0.7
Height	0.7	14.2	20.5	-4.5	-1.1	-3.0	-4.5	-1.9	-3.8	-3.5	1.7	-4.2	-4.4	-4.4	-4.5	-3.7	-4.4	-4.5
Cardiovascular Disease	0.7	2.2	9.2	-1.1	0.2	-3.0	-1.6	-1.0	-1.1	-0.8	0.8	-1.5	-2.5	-1.6	-2.0	0.8	-1.1	-0.1
Alcohol usually taken with meals	0.7	1.2	4.5	-0.8	2.1	0.5	-0.8	-0.0	-1.1	-0.2	-0.2	-1.9	-1.3	-0.9	-1.1	-1.0	-1.0	-1.0
Hair/balding pattern: Pattern 2	0.7	0.9	2.1	-1.1	0.5	1.0	-1.0	-0.2	-1.2	-0.1	-0.6	-1.1	-0.3	-1.3	-1.5	-0.8	-0.8	-1.0
Noisy workplace	0.7	0.9	5.1	0.5	-1.2	0.8	0.1	-0.3	0.4	0.6	1.5	1.0	0.1	-0.2	0.4	2.3	-0.0	1.4
Pulse wave Arterial Stiffness index	0.7	0.8	5.6	-0.4	-0.6	-1.5	0.0	0.1	-0.0	-1.6	-0.0	-2.4	1.0	-0.2	0.0	-0.8	-0.1	-0.6
Shortness of breath walking on level ground	0.7	0.8	2.2	-0.7	-0.2	-1.1	-0.9	-1.5	-0.5	-1.4	-0.4	-1.2	-1.1	-1.1	-0.8	0.3	-0.5	-0.0
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.9	1.0	-0.4	1.2	0.7	0.7	1.0	-0.3	0.2	0.1	2.0	0.8	1.1	0.9	0.6	1.0
Long-standing illness, disability or infirmity	0.7	1.0	3.0	-1.1	-0.7	-1.7	-1.4	-0.7	-0.9	-0.1	0.5	-0.4	-1.1	-1.2	-1.6	-0.3	-0.9	-0.8
Mineral and other dietary supplements	0.7	0.9	4.2	0.3	-2.0	-0.6	-0.1	-0.3	-0.6	-0.1	2.0	-0.7	1.1	0.0	0.0	1.2	-0.5	0.8
Arm fat-free mass (left)	0.7	3.8	8.2	-2.0	0.0	-2.0	-2.4	-1.1	-2.4	-1.3	2.2	-2.9	-0.6	-2.3	-2.3	-0.8	-2.6	-1.6
Arm predicted mass (left)	0.7	3.6	7.7	-2.0	-0.0	-2.1	-2.3	-1.1	-2.3	-1.2	2.0	-2.8	-0.6	-2.3	-2.2	-0.9	-2.5	-1.6
Coronary Artery Disease (CAD)	0.6	0.7	2.1	0.9	0.9	1.0	0.4	0.5	0.5	1.5	-0.8	0.7	0.3	0.6	0.6	1.2	0.7	0.8
Average weekly spirits intake	0.6	0.8	3.4	-0.7	-0.4	-1.8	-1.0	-0.7	-0.9	-0.5	0.6	-0.7	-1.5	-0.6	-0.8	-0.5	-0.7	-0.6
Angina	0.6	0.8	2.6	-0.6	1.2	-1.0	-1.0	-1.6	-0.1	-0.9	-1.1	-0.2	-1.6	-0.7	-0.1	0.2	-0.2	-0.1
Townsend deprivation index at recruitment	0.6	0.8	5.8	0.2	0.3	0.6	0.3	1.2	0.6	2.4	0.7	-0.1	1.1	0.7	1.0	-0.9	0.4	-0.1
Age when periods started (menarche)	0.6	1.3	4.9	-1.2	0.4	-1.4	-1.2	-1.0	-1.7	0.1	0.2	-1.0	-2.2	-1.1	-1.1	-0.6	-1.2	-1.1
Supplements: Glucosamine	0.6	0.8	5.4	-0.1	0.5	0.7	0.3	0.2	1.1	-0.9	-2.3	-0.7	-0.4	0.2	-0.3	-1.1	0.8	-0.7
Sitting height	0.6	4.0	9.1	-2.1	-0.0	-1.6	-2.4	-1.1	-2.6	-1.6	2.2	-1.4	-2.2	-2.6	-2.3	-0.8	-3.0	-1.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.8	-0.9	1.1	-0.0	-1.0	-0.6	-1.2	0.1	-0.2	-0.6	-1.4	-0.9	-0.8	-0.6	-1.0	-0.8
Arm fat percentage (right)	0.6	2.3	4.6	2.1	0.3	-0.1	1.5	1.1	2.0	-0.3	-1.6	0.8	2.0	1.8	1.4	1.3	2.2	1.7
Trunk fat-free mass	0.6	3.7	7.1	-2.0	0.2	-1.7	-2.3	-1.2	-2.5	-1.4	2.2	-2.5	-0.6	-2.3	-2.3	-0.9	-2.7	-1.7
Time employed in main current job	0.6	0.7	5.7	0.2	0.8	-0.4	0.4	-0.7	0.7	-2.4	-0.9	-0.8	0.8	0.3	0.1	0.2	0.5	0.2
Falls in the last year	0.6	0.8	5.1	-0.3	-2.3	-1.1	-0.3	0.4	0.2	-1.2	-0.3	-0.8	0.1	0.1	-0.1	-1.2	0.5	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.2	-0.8	-0.9	0.4	-0.5	0.5	-0.3	0.9	-0.1	-1.4	-0.6	-0.2	-0.1	-1.8	-0.1	-1.1
Depression (self-reported)	0.6	0.7	1.5	-1.0	-0.9	-0.6	-0.7	-0.5	-1.2	0.8	0.5	-0.9	-0.8	-1.0	-0.9	-0.8	-0.9	-0.9
Trunk predicted mass	0.6	3.5	6.9	-1.9	0.2	-1.6	-2.3	-1.1	-2.4	-1.5	2.2	-2.5	-0.5	-2.2	-2.3	-0.9	-2.6	-1.6
Standing height	0.6	6.4	10.7	-2.7	-0.5	-2.0	-2.8	-1.1	-2.8	-2.6	2.0	-2.7	-3.0	-2.8	-3.0	-2.1	-3.3	-2.7
Breastfed as a baby	0.6	0.7	3.0	0.8	1.0	0.8	1.4	1.7	1.0	0.1	0.7	-0.5	0.1	1.0	0.2	-0.1	0.9	0.3
Tense / ‘highly strung’	0.6	1.0	3.5	0.8	1.5	-1.6	0.0	0.1	1.0	-0.2	-0.8	0.7	-0.1	0.5	0.4	1.9	1.2	1.7
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.4	0.9	1.3	0.3	1.0	0.3	1.5	-0.3	-0.6	0.8	0.7	1.0	0.8	1.0	1.0	1.0
Glaucoma (self-reported)	0.6	0.7	2.3	-0.2	-1.2	-1.2	-0.3	0.5	-0.7	-1.4	1.5	0.7	-1.4	-0.3	-0.2	-0.1	-0.3	0.1
High blood pressure (siblings)	0.6	0.8	3.9	0.2	0.7	-0.2	-0.4	-0.5	-0.1	0.2	1.4	2.0	-0.1	-0.5	0.3	2.0	-0.4	1.1
Exposure to tobacco smoke outside home	0.6	0.8	3.8	-0.6	-1.0	0.0	-0.0	0.9	-0.4	-0.2	-0.7	-1.5	0.9	-0.1	-0.1	-2.0	-0.1	-1.4
Comparative body size at age 10	0.6	1.6	3.1	-1.2	0.1	-1.6	-1.2	-0.7	-1.5	-1.8	0.9	-1.7	0.9	-1.0	-1.5	-1.1	-1.5	-1.5
Pulse wave peak to peak time	0.6	0.7	4.2	0.1	0.4	1.2	-0.4	-0.2	-0.3	1.2	0.2	2.1	-1.4	-0.2	-0.4	0.5	-0.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.4	0.8	1.2	0.8	0.6	-0.9	1.2	-0.0	-0.1	0.3	-0.1	0.9	1.0	1.1	1.0	1.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.0	1.1	0.0	0.2	0.9	0.6	0.2	0.8	1.2	1.4	1.1	0.8	0.9	0.7	0.5	0.9
Commuting to job workplace: Cycle	0.6	0.8	3.6	-0.9	-0.3	-1.2	-0.7	-0.3	-0.7	-0.4	1.6	-1.9	-0.1	-0.7	-0.7	-0.4	-0.5	-0.6
Myopia	0.6	0.8	2.4	1.1	0.2	0.6	1.1	1.0	1.1	-0.1	-1.6	0.6	0.7	1.2	0.8	0.3	1.4	0.6
Cholesterol lowering medication	0.6	0.8	4.5	-0.6	-0.9	-2.1	-0.5	-0.4	-0.5	-1.6	0.1	-1.4	-0.5	-0.6	-0.9	-0.0	-0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.9	0.7	1.3	-0.2	-0.0	-0.2	0.7	-0.6	1.0	-0.0	0.3	0.1	0.5	2.2	0.4	1.5
Schizophrenia (2018)	0.5	1.0	3.3	1.0	1.8	1.4	0.4	0.2	1.4	0.7	0.2	0.8	1.1	1.0	0.7	1.2	1.0	1.2
Irritable Bowel Disease (IBD)	0.5	1.2	4.0	-1.2	-0.5	-0.9	-1.7	-0.0	-1.2	0.1	-0.2	-0.4	-2.0	-1.4	-1.0	-1.3	-1.1	-1.4
Age at First Birth	0.5	0.7	2.1	0.9	0.4	-0.0	1.1	0.7	1.1	-1.5	-0.5	0.2	1.0	1.1	0.7	0.2	1.1	0.5
LDL Cholesterol	0.5	0.7	3.1	0.3	1.2	0.0	0.1	-1.2	0.5	0.1	1.6	0.7	-0.1	0.1	0.5	1.8	0.1	1.2
Lupus	0.5	0.7	2.8	-0.7	-0.7	-1.7	-1.0	-0.4	-0.1	-0.6	-0.8	-0.8	-0.3	-0.8	-0.9	-1.1	-0.4	-1.2
Diabetes (father)	0.5	0.6	2.7	-0.1	-1.1	-0.5	-0.5	0.9	-0.1	-0.1	-1.6	-0.4	-1.2	-0.3	-0.4	-1.3	-0.1	-0.8
Severe depression (siblings)	0.5	0.6	3.1	0.4	-0.2	0.1	0.2	-0.0	0.4	0.0	1.5	1.8	0.1	0.0	0.2	1.4	0.1	1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.9	0.5	1.2	-0.9	0.1	1.0	0.3	-1.4	0.8	-0.1	-0.1	0.2	-0.1	1.2	0.5	0.9
Past tobacco smoking	0.5	0.9	3.7	0.8	0.1	1.2	1.4	1.9	0.6	-0.3	0.2	1.5	0.2	1.0	1.0	-0.4	0.6	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.9	-0.8	-1.3	-2.0	-1.0	-0.9	-0.5	-0.1	0.4	0.4	-0.8	-0.9	-0.9	0.4	-0.5	-0.2
Medication: Ramipril	0.5	0.7	2.8	0.5	1.0	0.3	0.4	0.0	-0.1	1.7	1.1	0.5	1.3	0.2	0.9	1.1	0.2	1.0
Impedance of arm (right)	0.5	2.5	10.2	1.7	0.1	1.1	1.8	1.3	2.0	-0.8	-3.2	1.6	-0.3	1.8	1.4	-0.3	2.2	0.7
Impedance of arm (left)	0.5	2.2	6.2	1.5	-0.2	1.1	1.7	1.3	2.0	-0.4	-2.5	2.2	-0.8	1.7	1.5	-0.2	2.0	0.7
Worry too long after embarrassment	0.5	0.8	3.7	-0.7	0.1	-1.9	-0.7	-0.2	-0.2	-0.9	-1.0	-0.1	-1.6	-0.9	-1.2	0.2	-0.2	-0.4
Number of children fathered	0.5	0.5	2.0	-0.9	-0.9	-0.5	-0.7	-0.6	-0.8	-0.2	0.5	-1.4	-0.6	-0.5	-0.6	-0.5	-0.8	-0.9
Whole body fat-free mass	0.5	2.8	5.4	-1.7	0.1	-1.7	-2.1	-1.0	-2.1	-1.0	2.0	-2.2	-0.4	-2.1	-2.0	-0.6	-2.3	-1.4
Arm fat percentage (left)	0.5	2.1	4.1	2.0	0.2	-0.1	1.5	1.1	1.9	-0.1	-1.3	1.1	1.9	1.7	1.5	1.4	2.0	1.7
Loneliness, isolation	0.5	0.8	4.0	0.4	0.8	-1.0	-0.1	-0.7	0.3	0.3	1.8	-0.1	-0.2	0.0	0.0	2.0	-0.1	1.3
Friendships satisfaction	0.5	0.6	2.6	0.9	0.0	0.4	0.4	0.9	0.4	-0.1	-0.2	1.6	0.2	0.8	1.1	0.8	0.6	0.9
Commuting to job workplace: Walk	0.5	0.6	3.6	-0.3	1.5	0.1	-0.4	-1.9	-0.1	0.1	0.1	0.2	-1.1	-0.3	-0.7	0.5	-0.3	0.2
Whole body water mass	0.5	3.0	5.8	-1.7	0.0	-1.8	-2.2	-1.0	-2.2	-1.2	2.2	-2.2	-0.4	-2.1	-2.0	-0.6	-2.4	-1.4
Hearing aid user	0.5	0.6	5.7	0.4	1.0	-0.7	-0.2	2.4	-0.4	-0.4	0.5	0.8	-0.4	0.2	0.0	-0.4	0.0	-0.1
Mother’s age at death	0.5	0.6	1.2	0.7	-0.1	0.4	0.9	-0.4	0.6	-1.0	-1.0	0.9	0.7	1.0	0.9	0.4	1.1	0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.7	3.9	-0.0	1.4	0.0	0.4	0.3	0.7	-0.1	-2.0	1.4	-0.4	0.2	0.2	-1.0	0.7	-0.6
Fasting Glucose	0.4	0.5	1.7	0.4	-0.6	-0.5	0.7	0.3	1.3	0.3	-0.9	0.6	0.3	0.7	0.1	-0.9	1.0	-0.2
Blood Platelet Count	0.4	4.6	11.4	2.5	2.8	0.8	1.9	0.6	1.9	-1.1	0.0	3.4	-0.1	1.9	2.2	3.3	2.1	3.2
Blood White Count	0.4	3.0	6.9	1.9	1.2	1.8	1.4	-0.0	1.8	2.1	-1.4	1.8	1.6	1.5	1.4	2.6	1.5	2.5
Type 2 Diabetes (T2D) (2018)	0.4	0.7	3.0	-0.7	-0.3	-1.4	-0.5	-1.1	-0.2	-1.2	0.3	-1.0	-1.7	-0.6	-0.5	-0.1	-0.2	-0.2
Relative age of first facial hair	0.4	0.8	1.8	-1.1	-0.2	-1.2	-0.9	-0.0	-1.0	-1.0	0.5	-0.8	-0.8	-0.9	-1.0	-0.9	-1.0	-1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.5	0.2	-1.5	-0.3	0.2	0.2	0.6	-0.3	-0.0	0.1	1.6	0.4	0.4	0.2	0.6	0.4
Nervous feelings	0.4	0.8	3.6	-0.7	0.6	-1.9	-0.6	0.3	-0.2	-1.3	-1.5	0.1	-1.2	-0.7	-1.0	0.1	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.5	-0.5	-0.0	-1.2	-0.7	-1.1	-0.6	-1.6	1.9	0.1	-1.5	-0.7	-0.7	0.8	-1.0	0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.5	-0.4	1.2	-0.4	-1.0	-0.5	-0.7	-0.1	1.1	1.1	-0.7	-0.7	-0.9	0.5	-0.6	0.2
Father’s age at death	0.4	0.6	2.3	-0.1	-1.4	1.0	0.1	-0.9	-0.1	1.1	-1.5	0.2	0.2	0.2	0.4	-0.9	0.3	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.1	1.0	-0.3	0.9	1.0	0.6	1.1	0.0	-1.4	1.2	-0.7	0.9	0.7	0.2	1.4	0.6
Asthma	0.4	0.7	7.3	0.2	0.7	0.1	0.1	-1.1	0.7	0.7	-2.7	0.5	0.0	0.3	0.1	0.1	0.7	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.8	-0.5	0.5	-1.4	-0.8	-0.6	-0.3	0.0	1.0	-0.4	-1.3	-1.1	-0.7	1.1	-0.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.9	-0.8	0.4	0.0	-0.7	-0.9	-0.8	-0.4	0.3	-0.1	-0.3	-1.2	-1.4	0.3	-0.9	-0.3
Angina (self-reported)	0.4	0.6	2.2	-0.5	1.3	-0.8	-0.9	-1.3	-0.0	-0.6	-0.7	-0.0	-1.5	-0.7	0.0	0.3	-0.1	-0.0
Overall health rating	0.4	0.8	3.2	-0.5	-0.1	-1.8	-1.4	-0.8	-0.6	0.1	0.5	0.3	-1.3	-1.1	-1.0	0.8	-0.5	0.3
Had major operations	0.4	0.4	1.1	0.5	0.4	-0.2	0.4	1.0	0.6	-0.4	-0.8	-0.3	1.1	0.7	0.8	-0.6	0.9	-0.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.3	-0.8	0.0	-0.6	-0.7	0.0	-0.9	0.1	0.4	-0.9	-0.5	-0.6	-0.6	-1.1	-0.5	-1.0
Supplements: Vitamin C	0.4	0.5	1.1	0.7	0.3	0.8	1.1	0.5	0.9	-0.4	-0.3	0.3	0.3	0.8	1.0	0.4	1.1	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.6	0.4	-0.5	1.2	0.8	0.2	0.0	1.6	-0.4	0.2	0.5	0.8	0.5	-0.8	0.6	-0.3
Illnesses of father: Heart disease	0.4	0.5	2.3	0.1	0.9	-0.2	-0.2	-0.7	0.1	0.8	1.1	-0.1	0.4	-0.3	0.6	1.5	0.1	1.1
Illnesses of siblings: Diabetes	0.4	0.5	1.4	0.6	0.9	0.6	0.9	0.7	1.0	-0.6	-0.4	1.2	0.5	0.6	0.7	-0.0	0.7	0.5
Diabetes diagnosed by doctor	0.4	0.6	1.6	-0.9	-0.8	-1.3	-0.7	-0.6	-0.7	-0.8	1.1	-0.5	-0.8	-0.8	-0.6	-0.4	-0.7	-0.6
Ever taken oral contraceptive pill	0.4	0.4	1.2	-0.8	0.3	-1.1	-0.9	-0.3	-0.7	-0.6	0.5	-0.6	-0.9	-0.8	-0.2	-0.0	-0.5	-0.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	3.7	-0.6	-0.6	-0.4	-0.6	-0.2	-0.1	0.3	1.9	-1.3	0.3	-0.4	-0.1	-0.4	-0.6	-0.4
Commuting to job workplace: Public transport	0.4	0.5	2.0	0.3	0.5	0.7	0.0	-0.6	0.7	1.4	0.2	1.2	-0.5	0.0	-0.0	1.4	0.0	0.8
Medication: Paracetamol	0.4	0.6	1.9	-0.5	-0.1	-0.7	-1.1	-1.4	-0.0	1.3	0.3	0.3	-1.2	-0.9	-0.9	0.7	-0.6	0.0
Ever smoked	0.4	0.7	2.3	0.8	0.7	0.3	0.3	-0.6	0.6	1.5	0.3	-0.3	0.9	0.6	0.4	1.5	0.7	1.4
Basal metabolic rate	0.4	2.3	4.4	-1.4	0.1	-1.9	-1.9	-0.8	-1.9	-1.1	1.7	-2.1	-0.3	-1.8	-1.8	-0.5	-2.0	-1.2
Risk taking	0.4	0.6	3.1	0.4	1.8	-1.6	0.3	0.8	-0.0	0.1	-0.6	-0.3	0.8	0.4	0.7	0.2	0.4	0.3
Alzheimer’s Disease (in father)	0.3	0.4	1.4	-0.4	-0.4	-0.2	-0.4	0.6	-0.9	-0.5	1.2	-1.0	-0.5	-0.4	-0.3	-0.6	-0.4	-0.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.4	0.7	0.7	1.2	0.7	0.5	0.6	0.5	0.4	-0.5	0.7	0.8	0.5	-0.2	0.5	0.3
Crohns Disease (2017)	0.3	0.6	3.2	-0.4	-1.8	0.7	-0.7	0.7	-0.7	0.0	-0.1	-0.3	-0.3	-0.7	-0.6	-1.2	-0.4	-1.3
Body Mass Index (BMI) (2010)	0.3	0.4	1.8	-0.5	-0.2	-1.3	-0.8	-1.1	-0.4	-0.7	0.3	-0.3	0.1	-0.6	-0.9	-0.2	-0.4	-0.4
HDL Cholesterol	0.3	0.4	3.5	0.1	1.9	0.8	0.4	0.8	0.0	0.5	-0.3	0.4	-0.7	0.3	0.2	-0.6	0.3	-0.3
Neuroticism (2016)	0.3	0.4	1.4	0.5	1.2	-0.7	0.0	0.1	0.2	0.4	-0.7	1.2	-0.6	0.2	-0.2	1.1	0.3	0.7
Primary Biliary Cirrhosis	0.3	0.4	2.2	-0.7	-0.3	-0.8	-0.3	0.3	-0.2	-0.4	-0.6	-0.6	0.1	-0.3	-0.3	-1.5	-0.2	-1.3
Triglycerides	0.3	0.5	2.9	-0.1	0.5	-1.7	-0.1	-1.5	0.1	-1.3	0.2	-0.3	-0.1	0.0	-0.3	0.4	-0.2	0.1
Smoking Status	0.3	0.8	2.4	1.0	-0.3	-0.2	0.6	0.1	1.1	1.1	-0.2	0.4	1.1	0.9	0.8	1.4	1.1	1.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.5	-0.1	-0.2	-0.4	-0.5	-1.1	0.7	0.1	0.8	0.7	0.0	-0.4	-0.2	1.2	0.1	0.9
Trunk fat percentage	0.3	1.1	2.5	1.5	-0.1	-0.4	1.0	1.0	1.6	-0.4	-1.1	0.3	0.9	1.2	1.1	1.0	1.6	1.3
Qualifications: CSEs or equivalent	0.3	0.4	2.1	0.4	1.2	-0.1	0.8	-0.5	0.7	-1.4	-0.2	0.3	-0.2	0.6	0.1	0.4	0.5	0.5
Medication: Simvastatin	0.3	0.4	2.1	0.3	-1.2	-1.4	0.0	0.3	0.4	-0.5	-0.1	0.4	-0.4	-0.1	0.1	0.9	0.3	0.6
Mouth/teeth dental problems: Dentures	0.3	0.5	2.7	-0.5	-1.2	0.6	-0.4	-0.0	-0.2	-0.1	0.4	-1.6	0.8	-0.1	-0.2	-0.9	-0.0	-0.4
Prospective memory result	0.3	0.4	2.3	0.2	-0.2	-0.3	0.4	1.5	0.5	1.2	-0.4	-0.8	0.1	0.2	0.2	-0.7	0.2	-0.3
Exposure to tobacco smoke at home	0.3	0.3	2.1	-0.1	-0.5	-0.5	-0.2	-0.6	-0.2	-1.4	-0.5	-0.4	0.9	-0.2	0.0	0.3	-0.2	0.1
Birth weight of first child	0.3	0.5	1.8	0.6	-1.3	-0.5	0.6	0.8	0.7	0.7	-0.7	1.1	0.7	0.4	0.7	0.2	0.7	0.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.3	-0.4	0.1	-1.1	-0.8	-0.2	-1.1	0.5	0.1	-0.0	-0.3	-0.8	-0.2	0.0	-0.7	-0.2
Headache pain in last month	0.3	0.5	2.2	-0.2	-0.7	-0.9	-0.7	-0.3	-1.0	1.5	0.8	0.8	-0.4	-0.6	-0.2	0.3	-0.7	0.1
Wheeze or whistling in the chest in last year	0.3	0.5	3.8	-0.4	-0.2	-0.9	-0.7	-0.7	-0.1	-0.2	-2.0	-0.9	-0.5	-0.3	-0.3	-0.5	0.1	-0.4
Health satisfaction	0.3	0.4	1.5	0.3	1.1	-0.5	-0.4	-0.1	-0.1	-1.2	-1.0	0.5	-0.8	0.1	0.2	0.6	0.3	0.5
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.2	0.6	0.1	-0.4	0.8	-0.1	1.0	-0.2	-0.0	0.1	1.0	1.1	0.7	-0.1	0.8	0.3
Migraine (self-reported)	0.3	0.3	3.7	0.2	-1.9	-0.4	0.4	0.4	0.2	0.6	0.5	0.2	0.3	0.3	-0.1	0.1	0.0	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.9	0.4	0.5	-0.6	0.3	-0.8	0.8	-0.4	-0.8	0.9	0.2	0.4	0.8	0.8	0.6	0.9
Alcohol intake frequency.	0.3	0.6	2.9	-0.2	-1.2	0.5	0.3	0.9	-0.3	0.8	-1.4	-0.3	0.5	0.1	0.1	-1.7	-0.2	-1.2
Eye problems/disorders: Cataract	0.3	0.4	2.1	0.8	0.1	0.4	0.2	0.3	0.4	-1.5	-0.8	0.2	0.3	0.4	0.8	0.3	0.7	0.6
Asthma (self-reported)	0.3	0.6	6.7	-0.0	0.7	-0.0	-0.1	-1.0	0.5	0.8	-2.6	0.4	-0.3	0.2	0.0	-0.1	0.5	0.0
Illnesses of father: None of the above (group 1)	0.3	0.3	1.8	-0.0	-1.4	0.2	0.3	-0.1	0.7	-0.8	-1.0	0.3	0.6	0.3	-0.1	-0.3	0.3	-0.1
Average weekly champagne plus white wine intake	0.3	0.3	1.8	0.0	0.6	0.6	-0.3	-0.7	-0.4	1.3	-0.3	0.4	0.3	-0.5	0.4	1.0	-0.3	0.5
Irritability	0.3	0.5	3.2	-0.1	-1.3	-1.8	-0.7	-0.2	-0.6	0.8	0.0	-0.2	0.3	-0.5	0.0	0.8	-0.1	0.3
Impedance of whole body	0.3	1.3	5.4	0.9	0.1	0.7	1.2	0.9	1.5	-0.7	-2.3	1.0	-1.5	1.1	0.9	-0.5	1.5	0.2
Bipolar Disorder or Schizophrenia	0.2	0.4	1.1	-0.8	0.9	-0.1	-0.9	-1.0	-0.8	-0.3	0.5	-0.3	-0.3	-0.5	-0.7	-0.2	-0.7	-0.4
Breast Cancer	0.2	0.5	2.0	0.1	0.5	-0.8	0.2	0.2	-0.3	-1.4	0.5	-1.3	1.4	0.0	-0.4	0.2	-0.4	0.2
Schizophrenia (2014)	0.2	0.5	2.5	0.4	1.6	0.3	0.2	-0.8	0.6	-0.8	0.6	-0.1	0.9	0.5	0.4	0.8	0.5	0.9
Blood Eosinophil Count	0.2	1.8	13.3	0.1	3.6	1.5	-0.2	-1.4	-0.0	0.6	1.7	0.9	-1.4	-0.3	0.6	1.6	-0.5	1.0
Blood Red Count	0.2	1.7	5.3	1.1	-0.0	1.7	1.6	1.9	0.4	1.9	-2.3	0.1	1.0	1.3	1.4	-1.0	0.9	-0.2
BMI	0.2	1.4	4.3	1.6	0.6	-0.2	1.0	1.1	1.3	0.2	0.2	-0.2	2.1	1.2	0.9	1.7	1.4	1.7
Systolic Blood Pressure	0.2	1.2	2.8	1.4	0.8	1.7	1.4	1.0	0.9	0.9	-0.8	1.5	0.0	1.3	1.2	0.7	1.0	1.2
Impedance of leg (right)	0.2	1.1	4.8	-0.7	-0.1	-0.8	-0.1	-0.5	0.0	-1.8	-1.9	-1.2	-2.2	-0.3	-0.6	-1.2	0.1	-0.9
Leg fat-free mass (left)	0.2	1.1	2.5	-0.9	-0.1	-1.6	-1.4	-0.5	-1.3	-0.7	1.2	-1.3	0.3	-1.3	-1.2	-0.2	-1.4	-0.8
Relative age voice broke	0.2	0.3	0.8	-0.4	0.7	-0.7	-0.7	-0.6	-0.8	-0.5	0.9	0.2	-0.2	-0.7	-0.3	0.6	-0.7	0.1
Taking other prescription medications	0.2	0.2	1.5	-0.1	-1.2	-1.0	-0.6	0.0	0.0	0.4	-0.3	0.2	-0.1	-0.3	-0.2	0.4	0.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.7	0.2	0.1	-0.4	0.2	-0.5	0.0	-1.3	1.1	0.8	-0.7	0.1	-0.1	0.9	-0.2	0.6
Medication: Atenolol	0.2	0.2	0.7	0.1	-0.2	0.4	0.2	0.6	0.8	0.8	0.2	0.7	-0.4	0.1	0.5	-0.1	0.3	0.1
Body mass index (BMI)	0.2	0.7	3.1	1.1	0.3	-0.8	0.6	0.6	0.7	0.2	-0.0	0.0	1.8	0.7	0.6	1.2	0.8	1.1
Impedance of leg (left)	0.2	1.0	6.4	-0.6	0.1	-0.1	-0.2	-0.3	0.1	-1.5	-1.5	-0.8	-2.5	-0.4	-0.6	-1.1	0.1	-0.8
Leg predicted mass (left)	0.2	1.1	2.6	-0.9	-0.1	-1.6	-1.4	-0.5	-1.3	-0.7	1.2	-1.3	0.3	-1.3	-1.2	-0.2	-1.4	-0.7
Mouth/teeth dental problems	0.2	0.3	0.7	0.7	0.6	-0.1	0.8	0.6	0.0	0.5	0.1	0.8	0.8	0.5	0.8	0.5	0.1	0.4
Diabetes (self-reported)	0.2	0.3	1.0	-0.5	-0.3	-0.8	-0.5	-0.6	0.0	-1.0	0.7	-0.4	-0.7	-0.5	-0.4	0.2	-0.2	-0.0
Length of working week for main job	0.2	0.2	0.8	0.0	-0.5	-0.4	-0.6	-0.2	-0.0	0.2	-0.1	0.7	0.9	-0.1	0.4	0.8	0.1	0.6
Hair/balding pattern: Pattern 4	0.2	0.5	1.6	0.4	-0.4	1.1	0.1	0.2	0.8	1.2	-1.3	0.3	0.7	0.0	0.7	0.8	0.4	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	3.3	-0.3	0.0	-1.8	-0.3	0.0	-0.3	-0.3	-0.8	-0.3	0.3	-0.2	-0.4	-0.8	-0.1	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.0	-0.1	-0.5	-1.0	-0.3	-0.2	0.4	-0.2	-0.9	0.3	0.1	-0.3	-0.2	0.6	0.4	0.4
Body fat percentage	0.2	1.0	2.1	1.4	-0.0	-0.6	0.8	0.9	1.4	-0.6	-1.1	0.1	1.0	1.1	0.9	0.9	1.4	1.2
Leg fat percentage (right)	0.2	0.8	2.0	1.1	-0.1	-1.0	0.7	0.8	1.1	-0.9	-1.4	-0.5	0.8	0.9	0.5	0.6	1.3	0.8
Number of full brothers	0.2	0.3	1.7	0.4	0.4	1.3	0.4	0.4	0.2	0.2	-0.4	0.2	0.9	0.5	0.3	-0.0	0.1	0.2
Age at first live birth	0.2	0.3	1.4	-0.0	-0.1	0.1	0.4	-0.0	0.4	0.5	-0.9	1.2	-0.6	0.3	0.6	-0.6	0.6	-0.3
Qualifications: College or University degree	0.2	0.7	1.8	1.1	0.9	-0.3	0.8	1.3	0.7	0.2	-0.3	0.9	0.1	0.6	1.1	1.0	1.2	1.1
Medication: Omeprazole	0.2	0.2	0.9	0.1	-0.1	0.1	0.0	-0.5	0.3	0.9	0.0	0.8	-0.5	-0.2	-0.3	0.9	0.4	0.7
Comparative height size at age 10	0.2	1.0	3.9	-0.9	-0.3	-0.5	-1.1	-0.4	-0.8	-2.0	1.6	-0.6	-0.5	-1.1	-1.3	-0.5	-1.3	-0.6
Leg fat-free mass (right)	0.2	1.2	2.5	-0.9	-0.1	-1.4	-1.5	-0.4	-1.4	-0.6	1.5	-1.2	0.1	-1.3	-1.3	-0.2	-1.6	-0.8
Qualifications: nursing, teaching	0.2	0.3	0.8	-0.6	-0.5	-0.4	-0.4	-0.1	-0.7	0.1	0.2	-0.8	-0.9	-0.4	-0.4	-0.8	-0.3	-0.7
Back pain experienced in last month	0.2	0.2	1.6	-0.3	0.1	-0.6	-0.6	-0.0	0.2	1.3	0.4	0.7	-0.6	-0.3	-0.3	-0.4	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.4	-0.5	-1.0	0.1	-0.2	0.0	-0.8	-0.0	-0.5	0.4	-0.1	-0.5	-0.6	-1.2	-0.5	-1.0
Leg predicted mass (right)	0.2	1.2	2.5	-0.9	-0.1	-1.3	-1.5	-0.4	-1.4	-0.5	1.5	-1.2	0.1	-1.4	-1.3	-0.2	-1.6	-0.8
Wears glasses or contact lenses	0.2	0.3	1.8	0.3	1.3	0.4	0.3	0.2	0.3	-0.5	0.5	0.6	0.3	0.1	0.5	0.5	0.2	0.4
Eye problems/disorders: Glaucoma	0.2	0.3	1.1	0.2	-0.8	0.2	0.3	0.2	0.1	-1.1	0.7	0.7	-0.7	0.2	0.1	0.5	0.1	0.7
Medication: Blood pressure	0.2	0.4	1.6	-0.4	0.3	-0.6	-0.4	-0.6	-0.4	-0.3	1.2	0.2	-1.3	-0.5	-0.4	0.5	-0.6	0.1
Leg fat percentage (left)	0.2	0.6	1.5	1.0	-0.0	-0.5	0.5	0.8	1.1	-0.8	-1.2	-0.4	0.6	0.8	0.3	0.6	1.2	0.7
Unable to work because of sickness or disability	0.2	0.3	0.6	0.6	0.1	-0.3	0.6	0.8	0.6	0.4	0.6	-0.0	0.5	0.7	0.5	0.3	0.6	0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.7	-0.1	-0.2	-0.3	-0.2	-0.4	0.2	0.7	0.6	0.6	-0.2	-0.4	-0.6	0.8	0.2	0.5
Alcohol drinker status: Previous	0.2	0.3	1.0	-0.4	-0.7	-1.0	-0.2	0.5	-0.5	0.9	0.5	-0.2	-0.4	-0.2	0.0	-0.8	-0.3	-0.3
Crohns Disease (2012)	0.1	0.2	0.6	0.1	-0.7	0.4	-0.1	0.7	0.2	-0.8	0.5	0.5	-0.3	-0.1	-0.4	0.0	0.1	-0.2
Heel T-Score	0.1	0.9	3.2	1.1	0.1	0.7	1.0	1.2	0.9	1.0	-0.1	1.8	0.5	1.1	1.6	0.3	0.8	0.7
Waist Hip Ratio (WHR)	0.1	0.3	1.7	0.4	-0.1	-0.4	0.4	0.7	-0.6	-1.3	0.7	-0.8	0.1	0.4	0.0	-0.1	-0.1	-0.2
Hypothyroidism (self reported)	0.1	0.3	1.3	-0.4	0.2	-1.1	-0.3	-0.5	-0.7	-0.0	-0.3	-0.5	0.2	-0.5	-0.7	-0.7	-0.5	-0.5
Respiratory disease	0.1	0.3	1.2	0.5	-0.4	-0.3	0.2	0.0	0.7	-0.2	-1.1	0.3	-0.5	0.4	0.5	0.4	0.8	0.7
Tanning	0.1	1.3	6.2	-0.9	0.5	0.3	-0.7	0.7	-1.4	0.9	-0.2	-2.5	-0.6	-0.7	-0.7	-1.9	-0.8	-1.6
Medication: Levothyroxine sodium	0.1	0.2	0.9	0.1	0.3	-0.8	0.3	0.6	0.1	0.2	-0.1	0.3	0.9	0.4	0.3	-1.0	0.2	-0.2
Trunk fat mass	0.1	0.4	0.8	0.9	-0.1	-0.7	0.3	0.6	0.8	-0.8	-0.3	-0.4	0.7	0.5	0.3	0.7	0.7	0.7
Waist circumference	0.1	0.5	1.7	0.9	0.2	-1.1	0.5	1.0	0.5	-0.8	0.1	-0.5	1.3	0.6	0.4	0.6	0.6	0.7
Had menopause	0.1	0.2	1.3	-0.1	-0.1	0.0	0.2	0.5	0.0	-0.4	-0.5	-1.2	0.2	-0.1	-0.2	-0.2	0.1	-0.2
Weight	0.1	0.5	2.7	-0.2	0.1	-1.7	-0.7	0.1	-0.5	-1.0	0.9	-1.1	0.3	-0.6	-0.7	0.2	-0.6	-0.1
Hip circumference	0.1	0.5	1.2	0.8	0.9	-0.7	0.2	0.5	1.0	-0.4	0.3	0.0	0.8	0.5	0.4	1.1	0.6	1.1
Arm fat mass (right)	0.1	0.4	1.4	0.8	0.2	-0.8	0.3	0.5	0.5	-0.4	-0.6	-0.4	1.2	0.5	0.3	0.5	0.6	0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.5	0.1	-1.2	0.6	0.1	0.1	0.6	-0.0	-0.4	-0.2	-0.7	0.1	-0.2	-0.4	0.4	-0.1
Whole body fat mass	0.1	0.3	0.9	0.7	0.0	-1.0	0.0	0.5	0.4	-0.6	-0.1	-0.6	0.7	0.3	0.2	0.6	0.4	0.6
Leg fat mass (right)	0.1	0.4	2.2	0.1	0.0	-1.5	-0.4	0.1	0.0	-1.2	-0.3	-1.1	0.4	-0.2	-0.5	0.3	0.1	0.1
Number of full sisters	0.1	0.1	1.0	-0.1	0.2	0.2	0.0	-0.3	-0.1	1.0	-0.7	-0.1	-0.1	-0.1	-0.4	-0.4	0.2	-0.3
Family relationship satisfaction	0.1	0.1	0.5	-0.1	0.1	0.2	-0.3	0.4	-0.3	0.4	-0.7	0.1	-0.6	-0.3	-0.3	0.0	-0.4	-0.2
Arm fat mass (left)	0.1	0.3	0.9	0.8	0.1	-0.9	0.2	0.4	0.5	-0.5	-0.3	-0.3	0.9	0.4	0.2	0.6	0.5	0.6
Leg fat mass (left)	0.1	0.3	1.8	0.2	0.0	-1.3	-0.4	0.2	0.0	-1.0	-0.3	-1.0	0.4	-0.2	-0.5	0.2	0.1	0.1
Hair Pigment	0.0	0.5	1.9	-0.0	0.4	1.0	0.4	0.2	-0.6	-0.3	-0.8	-0.1	1.4	0.4	-0.2	-1.4	-0.1	-0.9

Hub : Genes

SEP15

Models

Trait associations