Hub : Traits :

Hair/balding pattern: Pattern 4

797 significantly associated models · 178 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 7792411 9190254 1 1 4.0e-07 4.3e-07 1.0e+00 100 RP5-1115A15.1
2 1 10391536 12013869 4 2 4.3e-10 5.8e-84 6.7e-73 14 MASP2 MTOR
3 1 15829187 16844848 1 1 8.9e-08 1.9e-06 9.5e-03 70 ARHGEF19
4 1 23994201 26380805 7 3 1.2e-21 2.2e-44 2.3e-46 -5 CLIC4 RCAN3 RP3-465N24.5
5 1 40628071 42021616 1 1 6.8e-08 6.2e-18 3.3e-13 29 CITED4
6 1 117708477 120517959 3 2 8.9e-28 2.1e-33 2.5e-25 26 GDAP2 WARS2
7 1 151313774 152712747 1 1 1.5e-12 1.1e-19 1.1e-08 60 S100A11
8 1 152880672 154625632 3 2 1.2e-09 1.1e-09 1.0e+00 100 CRTC2 S100A16
9 1 168932500 171407761 5 5 9.2e-36 2.6e-44 3.5e-01 100 GORAB KIFAP3 PRRX1 SCYL3
10 2 31589414 33088870 2 1 6.2e-11 4.2e-22 1.1e-12 46 SPAST
11 2 42753863 44690514 2 2 3.3e-08 2.8e-11 1.3e-02 86 PLEKHH2 ZFP36L2
12 2 66927859 68326904 1 2 9.4e-11 9.1e-21 1.2e-20 1 ETAA1
13 2 69829251 71228388 1 1 7.8e-08 9.0e-06 2.3e-01 93 FAM136A
14 2 218736292 220632013 3 2 2.7e-08 1.8e-14 1.7e-06 61 RP11-33O4.1 WNT6
15 2 241430049 242849135 1 1 7.2e-08 8.1e-07 6.6e-04 52 ANO7
16 3 40537829 41986787 1 1 2.2e-08 1.4e-08 4.3e-02 87 CTNNB1
17 3 124951821 127452273 2 2 3.8e-11 3.3e-27 1.5e-23 14 ALG1L PLXNA1
18 3 134986214 136558759 1 1 8.4e-09 7.3e-09 1.0e+00 100 PPP2R3A
19 3 138380069 139954262 3 3 6.8e-22 2.4e-86 7.5e-61 30 RBP1 RP11-219D15.3
20 3 140350567 142017527 2 1 3.3e-18 3.1e-19 1.0e+00 100 ZBTB38
21 3 151262987 152878838 2 1 1.5e-14 8.8e-17 1.2e-09 46 MBNL1
22 3 157127290 158951696 1 2 2.8e-08 6.7e-18 1.0e-08 56 RSRC1
23 4 53557678 55022796 1 1 8.5e-08 2.7e-10 3.8e-04 68 FIP1L1
24 4 80407869 82578407 3 2 7.5e-39 8.0e-40 1.0e+00 100 C4orf22 PRDM8
25 4 107145847 108895012 1 1 5.2e-10 6.2e-13 6.0e-07 52 DKK2
26 4 153688776 155252934 1 1 1.4e-08 1.1e-09 1.9e-02 85 KIAA0922
27 5 65978497 67792548 1 1 3.0e-09 1.2e-10 8.5e-09 20 RP11-434D9.1
28 5 121417687 123054717 3 2 5.2e-10 1.5e-20 2.4e-14 33 CTB-36H16.2 SNX2
29 5 171053425 172577403 1 1 3.8e-12 9.8e-14 1.0e+00 100 SH3PXD2B
30 6 19840492 21930988 1 1 4.9e-08 2.4e-16 7.8e-17 -3 CDKAL1
31 6 37093486 38816574 1 1 1.1e-07 8.7e-08 3.0e-01 96 ZFAND3
32 6 44079216 46043561 1 1 3.6e-14 7.8e-22 4.2e-12 48 SUPT3H
33 6 105033213 107467855 2 2 9.6e-12 2.9e-26 7.2e-19 30 ATG5 PREP
34 6 110883139 112286687 1 1 2.0e-07 9.5e-10 3.8e-14 -53 KIAA1919
35 6 125970401 127355237 1 1 7.4e-27 1.2e-27 6.8e-03 94 CENPW
36 6 169458730 170872572 1 1 3.9e-09 8.0e-11 2.2e-04 68 ERMARD
37 7 18364750 19854141 1 2 6.4e-75 1.8e-113 4.0e-48 58 TWIST1
38 7 67408820 70954231 2 2 6.8e-09 1.2e-63 2.2e-54 15 AUTS2 RP5-859M6.1
39 7 130101373 131880252 2 2 3.6e-12 4.3e-16 3.7e-04 81 MKLN1-AS2
40 7 139519806 141413051 2 2 2.3e-08 7.0e-09 1.2e-02 81 DENND2A MRPS33
41 8 108216908 110190556 2 2 5.3e-19 2.3e-25 2.0e-09 67 EMC2 RSPO2
42 9 12410173 13977570 1 1 7.5e-12 1.5e-12 8.3e-03 86 MPDZ
43 9 128394623 129961152 1 1 1.0e-11 1.5e-14 2.2e-05 70 MVB12B
44 10 31857752 33353843 1 1 2.8e-07 7.0e-11 5.5e-05 62 EPC1
45 10 76664253 80383574 3 3 6.3e-31 1.8e-35 3.4e-08 80 C10orf11 DLG5
46 10 125455780 127372751 4 4 2.1e-19 3.7e-34 7.9e-08 81 METTL10 ZRANB1
47 11 26693196 28189639 1 1 1.7e-07 6.7e-11 1.4e-05 56 LGR4
48 11 43408419 45340720 2 2 2.3e-07 1.7e-30 8.1e-23 27 CD82 EXT2
49 11 60839578 62346131 5 1 1.8e-08 2.3e-08 1.0e+00 100 TMEM258
50 11 68367007 69880281 1 1 5.0e-10 9.7e-10 1.5e-09 2 MYEOV
51 12 28611779 30185513 2 2 4.3e-11 9.1e-22 1.0e-10 55 FAR2 RP11-996F15.2
52 12 49780778 51912062 6 1 4.8e-11 7.9e-10 6.3e-01 99 ATF1
53 13 30336006 31886850 1 1 4.3e-11 4.4e-18 9.2e-17 8 HMGB1
54 15 89921477 91886448 4 2 7.4e-13 8.4e-12 1.0e+00 100 CRTC3 RP11-617F23.1
55 16 66666637 68802936 12 2 1.1e-18 4.6e-15 3.7e-01 99 CTCF RLTPR
56 17 1263564 2923933 2 1 2.2e-12 6.4e-12 1.0e+00 100 SRR
57 17 42413481 45876022 35 2 1.3e-61 1.0e-58 1.0e+00 100 HEXIM1 LRRC37A2
58 17 54272304 55667722 1 1 3.9e-09 3.8e-32 7.0e-25 24 MIR3614
59 19 41165252 42626207 7 1 1.5e-13 2.4e-13 1.0e+00 100 EXOSC5
60 20 20990627 22430527 2 1 7.1e-33 1.7e-125 1.9e-96 24 RPL41P1
61 20 30716979 32128889 1 1 8.2e-08 1.1e-07 4.3e-02 86 MAPRE1
62 20 32254831 34484245 5 1 3.4e-08 2.8e-07 5.0e-01 98 TRPC4AP
63 20 39114404 40683594 2 1 5.0e-11 6.9e-22 1.2e-12 46 LPIN3
64 22 28478985 29894210 2 2 6.5e-13 2.7e-13 2.4e-01 97 CCDC117
65 22 45006830 46436332 1 1 3.5e-07 2.2e-11 4.1e-06 53 FAM118A

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Crohns Disease (2017) 1.40 3 2 6.1 0.00 1.00000 TMEM258 ZBTB38 ZFP36L2
Irritable Bowel Disease (IBD) 1.26 2 1 3.0 0.00 1.00000 KIAA1919 ZFP36L2
Verbal and Numeric Reasoning (VNR) 1.16 3 0 0.0 0.00 1.00000 CENPW MAPRE1 TMEM258
Breast Cancer 1.50 5 3 9.1 0.61 0.27234 CDKAL1 GDAP2 LRRC37A2 METTL10 ZBTB38
Ovarian Cancer 1.19 1 1 3.0 0.00 1.00000 LRRC37A2
Prostate Cancer 2.22 3 1 3.0 0.00 1.00000 ANO7 CRTC2 MBNL1
Age at First Birth 1.11 1 1 3.0 0.00 1.00000 CRTC2
Bipolar Disorder 1.83 1 0 0.0 0.00 1.00000 ZRANB1
Crohns Disease (2012) 1.50 2 0 0.0 0.00 1.00000 TMEM258 ZFP36L2
Fasting Glucose 1.44 1 1 3.0 0.00 1.00000 TMEM258
HDL Cholesterol 1.31 1 1 3.0 0.00 1.00000 TMEM258
LDL Cholesterol 1.48 1 1 3.0 0.00 1.00000 TMEM258
Neuroticism 1.09 1 0 0.0 0.00 1.00000 LRRC37A2
Primary Biliary Cirrhosis 1.00 1 0 0.0 0.00 1.00000 LRRC37A2
Schizophrenia 1.24 1 1 3.0 0.00 1.00000 RP5-1115A15.1
Triglycerides 1.49 1 1 3.0 0.00 1.00000 TMEM258
Blood Eosinophil Count 1.05 11 7 21.2 -0.39 0.23500 ATG5 CLIC4 CTCF FAM136A LRRC37A2 MASP2 MTOR RLTPR RP5-1115A15.1 TMEM258 ZFP36L2
Blood Platelet Count 1.39 19 15 45.5 0.03 0.89211 ATF1 CDKAL1 CLIC4 CRTC2 CTB-36H16.2 ETAA1 FAM136A FAR2 GDAP2 LRRC37A2 MAPRE1 METTL10 PLEKHH2 PLXNA1 RP11-434D9.1 RP3-465N24.5 TMEM258 ZFAND3 ZFP36L2
Blood Red Count 1.72 17 10 30.3 0.54 0.02069 ATF1 AUTS2 C4orf22 CCDC117 CENPW CLIC4 CTCF FAM136A KIAA1919 LRRC37A2 RLTPR SUPT3H TMEM258 TRPC4AP ZBTB38 ZFAND3 ZFP36L2
Blood White Count 1.32 12 6 18.2 0.00 0.99147 ANO7 ATF1 CENPW CITED4 CTB-36H16.2 EPC1 LPIN3 LRRC37A2 METTL10 RP5-1115A15.1 TMEM258 ZRANB1
Heel T-Score 2.89 31 22 66.7 -0.17 0.35659 ARHGEF19 ATF1 CCDC117 CRTC3 CTCF CTNNB1 EXOSC5 FAM118A GORAB LGR4 LPIN3 LRRC37A2 MASP2 METTL10 MPDZ MTOR PLEKHH2 PRRX1 RLTPR RP11-617F23.1 RP5-1115A15.1 RSPO2 SPAST SRR SUPT3H TMEM258 TRPC4AP TWIST1 WARS2 ZBTB38 ZFP36L2
BMI 0.84 10 6 18.2 -0.35 0.31745 C4orf22 CTNNB1 HMGB1 LGR4 MASP2 PPP2R3A RP5-859M6.1 RSRC1 SRR WARS2
Height 3.28 42 32 97.0 0.19 0.20154 ALG1L ANO7 ATF1 AUTS2 C10orf11 CENPW CRTC3 CTCF CTNNB1 DENND2A DLG5 EPC1 EXOSC5 FAM136A GORAB HEXIM1 KIAA1919 LRRC37A2 MAPRE1 MASP2 METTL10 MIR3614 MKLN1-AS2 MRPS33 PLEKHH2 PPP2R3A RLTPR RP11-33O4.1 RP11-996F15.2 RP3-465N24.5 RP5-1115A15.1 RPL41P1 RSRC1 SPAST SUPT3H TMEM258 TRPC4AP TWIST1 WARS2 WNT6 ZBTB38 ZFP36L2
Waist Hip Ratio (WHR) 2.44 17 14 42.4 -0.05 0.83977 CCDC117 CDKAL1 CENPW CTCF EPC1 ETAA1 HMGB1 LRRC37A2 MASP2 MYEOV PRRX1 RLTPR SH3PXD2B TRPC4AP WARS2 ZBTB38 ZFP36L2
Systolic Blood Pressure 1.84 13 8 24.2 -0.44 0.13171 ATF1 C10orf11 C4orf22 CLIC4 HEXIM1 LGR4 LRRC37A2 MKLN1-AS2 MYEOV PRDM8 RP5-1115A15.1 RSRC1 SRR
Smoking Status 1.13 4 2 6.1 -0.42 0.58477 CCDC117 HMGB1 RP5-1115A15.1 SRR
Allergy or Eczema 2.14 8 5 15.2 0.17 0.68260 ARHGEF19 CLIC4 CRTC3 MRPS33 RP11-617F23.1 RP5-1115A15.1 SRR ZBTB38
Cardiovascular Disease 1.58 7 1 3.0 -0.39 0.38233 ARHGEF19 C4orf22 CLIC4 FAM136A PRDM8 RP5-1115A15.1 ZFAND3
Hypothyroidism (self reported) 1.10 4 2 6.1 0.59 0.41282 CTCF RLTPR RP5-1115A15.1 TMEM258
Respiratory disease 1.24 2 2 6.1 0.00 1.00000 RP5-1115A15.1 TMEM258
Type 2 Diabetes (T2D) 1.54 3 2 6.1 0.00 1.00000 CDKAL1 CENPW ZFP36L2
Lung FEV1/FVC ratio 1.20 11 4 12.1 -0.24 0.47787 ANO7 ARHGEF19 C10orf11 CENPW CTCF CTNNB1 EMC2 LRRC37A2 RP5-1115A15.1 ZBTB38 ZFP36L2
Lung FVC 2.01 14 11 33.3 0.12 0.66642 ATF1 C10orf11 CENPW CTB-36H16.2 DENND2A FAM136A LRRC37A2 MRPS33 PLXNA1 RCAN3 RSRC1 TRPC4AP TWIST1 ZBTB38
Neuroticism 1.32 5 1 3.0 0.42 0.48306 CENPW LRRC37A2 MRPS33 RP5-1115A15.1 RSRC1
Chronotype (morning person) 0.96 1 0 0.0 0.00 1.00000 FAM118A
Hair Pigment 0.59 26 16 48.5 -0.31 0.11835 C4orf22 CDKAL1 CENPW EMC2 EPC1 EXOSC5 FAM136A FIP1L1 HMGB1 LRRC37A2 MAPRE1 MASP2 MIR3614 MTOR MYEOV PLXNA1 RCAN3 RP5-1115A15.1 RPL41P1 S100A16 SH3PXD2B SUPT3H TMEM258 TWIST1 ZBTB38 ZFP36L2
Tanning 0.22 1 0 0.0 0.00 1.00000 MAPRE1
Hand grip strength (left) 1.56 4 3 9.1 0.20 0.80371 DENND2A LRRC37A2 TRPC4AP ZBTB38
Number of treatments/medications taken 1.19 1 0 0.0 0.00 1.00000 TMEM258
Sensitivity / hurt feelings 1.30 1 1 3.0 0.00 1.00000 LRRC37A2
Frequency of depressed mood in last 2 weeks 1.08 2 0 0.0 0.00 1.00000 LRRC37A2 RP5-1115A15.1
Relative age of first facial hair 3.76 9 5 15.2 -0.84 0.00247 C4orf22 ETAA1 HEXIM1 LRRC37A2 MIR3614 MKLN1-AS2 SPAST TWIST1 ZBTB38
Systolic blood pressure, automated reading 1.80 8 6 18.2 0.74 0.03706 C4orf22 HEXIM1 LRRC37A2 MKLN1-AS2 RP5-1115A15.1 RSRC1 SRR TRPC4AP
Supplements: Zinc 1.28 1 0 0.0 0.00 1.00000 CD82
Diabetes (father) 1.49 2 1 3.0 0.00 1.00000 CDKAL1 ZFP36L2
Diabetes (mother) 1.43 1 1 3.0 0.00 1.00000 CDKAL1
Impedance of leg (right) 1.28 14 5 15.2 0.01 0.98245 ATF1 CTCF LPIN3 LRRC37A2 MASP2 MPDZ MVB12B MYEOV PLEKHH2 RLTPR SRR SUPT3H WARS2 ZFP36L2
Leg fat-free mass (left) 1.68 7 6 18.2 -0.60 0.15712 CENPW CTNNB1 EXOSC5 MAPRE1 MASP2 TRPC4AP ZBTB38
Trunk fat percentage 1.51 11 6 18.2 0.48 0.11093 ATF1 C10orf11 CENPW CTNNB1 HMGB1 LPIN3 LRRC37A2 METTL10 RP5-1115A15.1 SRR ZBTB38
Hand grip strength (right) 1.47 6 3 9.1 0.19 0.68579 HEXIM1 LRRC37A2 MAPRE1 METTL10 TRPC4AP ZBTB38
Current tobacco smoking 1.26 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Fed-up feelings 1.06 1 1 3.0 0.00 1.00000 LRRC37A2
Relative age voice broke 1.67 2 1 3.0 0.00 1.00000 LRRC37A2 MKLN1-AS2
Age when periods started (menarche) 1.20 2 1 3.0 0.00 1.00000 CENPW CRTC2
Heel bone mineral density (BMD) T-score, automated (left) 2.03 7 4 12.1 -0.20 0.66534 CRTC3 LPIN3 RP5-1115A15.1 SUPT3H TMEM258 TRPC4AP WARS2
Qualifications: CSEs or equivalent 1.39 1 0 0.0 0.00 1.00000 LRRC37A2
High blood pressure 1.81 5 2 6.1 0.66 0.22796 C4orf22 PRDM8 RP3-465N24.5 RP5-1115A15.1 SRR
Hayfever, allergic rhinitis or eczema 2.08 7 5 15.2 0.00 0.99418 CLIC4 CRTC3 MRPS33 RP11-617F23.1 RP5-1115A15.1 S100A11 ZBTB38
Diverticular disease/diverticulitis (self-reported) 1.18 1 0 0.0 0.00 1.00000 FAM118A
Medication: Atenolol 1.38 2 0 0.0 0.00 1.00000 C4orf22 MYEOV
Medication: Levothyroxine sodium 0.96 3 1 3.0 0.00 1.00000 CTCF RP5-1115A15.1 TMEM258
Sitting height 2.77 17 10 30.3 -0.35 0.15020 ATF1 CENPW CTNNB1 DENND2A DLG5 EXOSC5 FAM136A HEXIM1 LRRC37A2 MAPRE1 RSRC1 SPAST SUPT3H TMEM258 TRPC4AP TWIST1 ZBTB38
High blood pressure (mother) 1.09 2 0 0.0 0.00 1.00000 AUTS2 C4orf22
Body mass index (BMI) 0.87 6 1 3.0 0.62 0.19151 HMGB1 LGR4 MASP2 PPP2R3A RP5-1115A15.1 SRR
Impedance of leg (left) 1.29 12 6 18.2 0.10 0.76164 ATF1 CTCF LRRC37A2 MASP2 MPDZ MVB12B PLEKHH2 RLTPR SRR SUPT3H WARS2 ZFP36L2
Leg predicted mass (left) 1.68 8 6 18.2 -0.57 0.13717 CENPW CTNNB1 EXOSC5 MAPRE1 MASP2 SUPT3H TRPC4AP ZBTB38
Trunk fat mass 1.47 9 4 12.1 0.21 0.53905 ATF1 CTNNB1 HMGB1 LGR4 LPIN3 LRRC37A2 METTL10 RP5-1115A15.1 ZBTB38
Waist circumference 0.97 4 2 6.1 0.43 0.46426 CTNNB1 HMGB1 METTL10 ZBTB38
Number of incorrect matches in round 1.10 1 0 0.0 0.00 1.00000 PLXNA1
Past tobacco smoking 1.12 2 0 0.0 0.00 1.00000 SRR TRPC4AP
Nervous feelings 1.33 2 1 3.0 0.00 1.00000 CENPW LRRC37A2
Frequency of tenseness / restlessness in last 2 weeks 1.05 1 1 3.0 0.00 1.00000 LRRC37A2
Hearing difficulty/problems with background noise 1.20 1 0 0.0 0.00 1.00000 LRRC37A2
Hair/balding pattern: Pattern 2 4.83 13 7 21.2 -0.74 0.00367 C10orf11 C4orf22 CENPW CLIC4 EPC1 GORAB LGR4 LRRC37A2 PRDM8 PRRX1 RPL41P1 S100A11 TWIST1
Forced vital capacity (FVC) 2.20 12 8 24.2 -0.32 0.29305 C10orf11 CENPW CTB-36H16.2 CTNNB1 DENND2A FAM136A LRRC37A2 MRPS33 PLXNA1 RP3-465N24.5 RSRC1 ZBTB38
Heel bone mineral density (BMD) T-score, automated (right) 2.13 8 5 15.2 -0.07 0.86724 CRTC3 LPIN3 RP5-1115A15.1 SUPT3H TMEM258 TRPC4AP WARS2 ZBTB38
Ever unenthusiastic/disinterested for a whole week 1.35 1 0 0.0 0.00 1.00000 LRRC37A2
Qualifications: None of the above 1.35 1 0 0.0 0.00 1.00000 EMC2
Allergy 1.89 9 3 9.1 -0.02 0.95817 CLIC4 CRTC2 CRTC3 HEXIM1 MRPS33 RP11-617F23.1 RP5-1115A15.1 TMEM258 ZBTB38
Medication: Simvastatin 1.18 2 0 0.0 0.00 1.00000 MYEOV TMEM258
Fluid intelligence score 0.93 1 0 0.0 0.00 1.00000 CRTC2
Neuroticism score 1.24 2 1 3.0 0.00 1.00000 LRRC37A2 RP5-1115A15.1
Weight 1.46 8 6 18.2 -0.35 0.35726 CENPW CTNNB1 EXOSC5 LGR4 MASP2 METTL10 TRPC4AP ZBTB38
Impedance of arm (right) 1.13 8 4 12.1 0.26 0.50599 ATF1 CCDC117 CENPW LRRC37A2 MASP2 MPDZ PPP2R3A WARS2
Arm fat percentage (right) 1.12 6 3 9.1 0.98 0.00044 CENPW HMGB1 LGR4 METTL10 RP5-1115A15.1 SRR
Trunk fat-free mass 2.28 11 9 27.3 -0.66 0.02579 CENPW CRTC3 CTNNB1 DLG5 EXOSC5 FAM136A HEXIM1 MAPRE1 MASP2 TRPC4AP ZBTB38
Hip circumference 1.27 7 2 6.1 -0.20 0.62856 CTNNB1 MASP2 METTL10 PRRX1 TRPC4AP WARS2 ZBTB38
Time employed in main current job 1.02 1 0 0.0 0.00 1.00000 LRRC37A2
Father's age at death 1.00 1 0 0.0 0.00 1.00000 TWIST1
Worrier / anxious feelings 1.02 1 0 0.0 0.00 1.00000 LRRC37A2
Frequency of tiredness / lethargy in last 2 weeks 1.32 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Falls in the last year 1.18 1 0 0.0 0.00 1.00000 LGR4
Hair/balding pattern: Pattern 3 7.56 16 8 24.2 0.71 0.00088 C4orf22 CENPW CLIC4 LGR4 LPIN3 LRRC37A2 METTL10 MIR3614 PRDM8 RBP1 RP11-219D15.3 RP11-33O4.1 RPL41P1 S100A11 SPAST TWIST1
Number of live births 1.25 2 0 0.0 0.00 1.00000 LRRC37A2 TMEM258
Forced expiratory volume in 1-second (FEV1) 1.96 9 6 18.2 -0.34 0.34342 C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A2 RP3-465N24.5 RSRC1 ZBTB38
Pulse rate 1.53 4 2 6.1 0.08 0.91586 CTNNB1 MKLN1-AS2 TMEM258 ZBTB38
Noisy workplace 1.25 1 0 0.0 0.00 1.00000 CRTC2
Asthma 1.36 2 2 6.1 0.00 1.00000 RP5-1115A15.1 TMEM258
Medication: Cholesterol lowering 1.06 1 0 0.0 0.00 1.00000 HMGB1
Depression (self-reported) 1.08 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.85 7 7 21.2 -0.28 0.54701 C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A2 ZBTB38
Impedance of arm (left) 1.21 8 5 15.2 0.31 0.40973 ATF1 CCDC117 CENPW LRRC37A2 MASP2 MPDZ PPP2R3A WARS2
Arm fat mass (right) 1.05 8 2 6.1 0.47 0.19642 CTNNB1 HMGB1 LGR4 MASP2 METTL10 RP5-1115A15.1 SRR ZBTB38
Trunk predicted mass 2.27 11 8 24.2 -0.66 0.02605 CENPW CRTC3 CTNNB1 DLG5 EXOSC5 FAM136A HEXIM1 MAPRE1 MASP2 TRPC4AP ZBTB38
Standing height 3.10 27 20 60.6 -0.31 0.10098 ATF1 CENPW CRTC3 CTCF CTNNB1 DENND2A DLG5 EXOSC5 FAM136A HEXIM1 LRRC37A2 MAPRE1 MASP2 METTL10 PLEKHH2 PPP2R3A RLTPR RP11-33O4.1 RP3-465N24.5 RP5-1115A15.1 RSRC1 SPAST TMEM258 TRPC4AP TWIST1 WNT6 ZBTB38
Tense / 'highly strung' 1.06 1 1 3.0 0.00 1.00000 RP5-1115A15.1
Birth weight of first child 1.31 1 1 3.0 0.00 1.00000 ZBTB38
Peak expiratory flow (PEF) 1.42 3 1 3.0 0.00 1.00000 C10orf11 LRRC37A2 ZFP36L2
Medication: Paracetamol 1.54 1 1 3.0 0.00 1.00000 LRRC37A2
Headache pain in last month 1.38 2 1 3.0 0.00 1.00000 EXOSC5 LRRC37A2
Medication for cholesterol, blood pressure or diabetes 1.13 1 0 0.0 0.00 1.00000 C4orf22
Hypothyroidism/myxoedema (self-reported) 1.00 2 1 3.0 0.00 1.00000 RP5-1115A15.1 TMEM258
Birth weight 1.28 2 1 3.0 0.00 1.00000 CENPW SRR
Forced vital capacity (FVC), Best measure 2.12 11 6 18.2 -0.33 0.29713 C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A2 MRPS33 PLXNA1 RSRC1 TWIST1 ZBTB38
Body fat percentage 1.41 11 4 12.1 0.51 0.08840 ATF1 C10orf11 CENPW CTNNB1 HMGB1 LGR4 LPIN3 METTL10 RP5-1115A15.1 SPAST ZBTB38
Leg fat percentage (right) 1.32 8 2 6.1 0.44 0.27648 CENPW HMGB1 LPIN3 METTL10 PRRX1 RP5-1115A15.1 RSRC1 SPAST
Arm fat-free mass (right) 1.92 11 6 18.2 -0.60 0.05339 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 METTL10 SUPT3H TRPC4AP ZBTB38
Comparative body size at age 10 1.16 2 2 6.1 0.00 1.00000 ETAA1 SRR
Seen a psychiatrist for nerves, anxiety, tension or depression 1.03 1 0 0.0 0.00 1.00000 TMEM258
Wheeze or whistling in the chest in last year 1.48 2 0 0.0 0.00 1.00000 RP5-1115A15.1 TMEM258
Qualifications: College or University degree 1.02 4 1 3.0 -0.05 0.93650 CENPW LRRC37A2 METTL10 TRPC4AP
Medication for pain relief, constipation, heartburn 1.43 2 0 0.0 0.00 1.00000 LRRC37A2 PRDM8
Neck or shoulder pain in last month 0.99 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Medication: Blood pressure 1.41 2 2 6.1 0.00 1.00000 C4orf22 PRDM8
Whole body fat mass 1.30 8 5 15.2 0.17 0.65534 CTNNB1 HMGB1 LGR4 LPIN3 MASP2 METTL10 RP5-1115A15.1 ZBTB38
Leg fat mass (right) 1.17 8 3 9.1 0.21 0.58717 CTNNB1 HMGB1 LGR4 LPIN3 MASP2 METTL10 RP5-1115A15.1 ZBTB38
Arm predicted mass (right) 1.87 9 5 15.2 -0.68 0.04581 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MASP2 SUPT3H TRPC4AP ZBTB38
Pulse rate, automated reading 1.79 7 4 12.1 -0.44 0.27203 C4orf22 CTNNB1 KIAA0922 LPIN3 MKLN1-AS2 TMEM258 ZBTB38
Alcohol intake frequency. 0.97 2 1 3.0 0.00 1.00000 AUTS2 LRRC37A2
Comparative height size at age 10 3.28 21 14 42.4 -0.32 0.13648 CENPW CRTC3 CTCF CTNNB1 DLG5 EXOSC5 FAM136A LRRC37A2 MAPRE1 MASP2 METTL10 PLEKHH2 PPP2R3A RLTPR RP11-33O4.1 RP5-1115A15.1 TRPC4AP TWIST1 WARS2 ZBTB38 ZFP36L2
Suffer from 'nerves' 1.01 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Overall health rating 1.20 2 0 0.0 0.00 1.00000 AUTS2 SPAST
Hypertension (Self-reported) 1.85 7 3 9.1 0.73 0.06138 C4orf22 CLIC4 MYEOV PRDM8 RP3-465N24.5 RP5-1115A15.1 SRR
Forced expiratory volume in 1-second (FEV1), predicted 1.97 2 2 6.1 0.00 1.00000 CENPW ZBTB38
Whole body fat-free mass 2.03 10 7 21.2 -0.63 0.04900 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 SUPT3H TRPC4AP ZBTB38
Leg fat-free mass (right) 1.69 10 5 15.2 -0.61 0.06343 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 SUPT3H TRPC4AP ZBTB38
Arm fat percentage (left) 1.17 6 3 9.1 0.98 0.00068 CENPW HMGB1 LGR4 METTL10 RP5-1115A15.1 SRR
Handedness (chirality/laterality): Left-handed 1.26 1 1 3.0 0.00 1.00000 LRRC37A2
Mood swings 1.15 1 1 3.0 0.00 1.00000 LRRC37A2
Loneliness, isolation 1.29 2 0 0.0 0.00 1.00000 LRRC37A2 RP5-1115A15.1
Diabetes diagnosed by doctor 1.25 2 0 0.0 0.00 1.00000 CENPW ZFP36L2
Mouth/teeth dental problems: Mouth ulcers 1.26 1 1 3.0 0.00 1.00000 LRRC37A2
Medication for cholesterol 1.31 2 0 0.0 0.00 1.00000 C4orf22 MYEOV
Asthma (self-reported) 1.32 3 2 6.1 0.00 1.00000 RP5-1115A15.1 TMEM258 ZBTB38
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.49 3 1 3.0 0.00 1.00000 C10orf11 EPC1 LRRC37A2
Whole body water mass 2.01 10 8 24.2 -0.63 0.04954 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 SUPT3H TRPC4AP ZBTB38
Leg predicted mass (right) 1.71 10 5 15.2 -0.61 0.06303 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 SUPT3H TRPC4AP ZBTB38
Arm fat mass (left) 1.05 8 3 9.1 0.47 0.20069 CTNNB1 HMGB1 LGR4 MASP2 METTL10 RP5-1115A15.1 SRR ZBTB38
Average weekly champagne plus white wine intake 1.35 2 1 3.0 0.00 1.00000 LRRC37A2 TMEM258
Miserableness 1.19 2 1 3.0 0.00 1.00000 LRRC37A2 RP5-1115A15.1
Guilty feelings 1.23 1 0 0.0 0.00 1.00000 LRRC37A2
Medication: Blood pressure 1.67 3 1 3.0 0.00 1.00000 C4orf22 LRRC37A2 MYEOV
Supplements: Fish oil (including cod liver oil) 1.11 1 0 0.0 0.00 1.00000 TMEM258
High cholesterol (Self-reported) 1.11 2 0 0.0 0.00 1.00000 FAM136A TMEM258
Medication: Paracetamol 1.57 1 1 3.0 0.00 1.00000 LRRC37A2
Illnesses of father: High blood pressure 1.28 1 0 0.0 0.00 1.00000 C4orf22
Ever smoked 1.02 2 0 0.0 0.00 1.00000 CTNNB1 SRR
Basal metabolic rate 1.88 10 6 18.2 -0.53 0.09442 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 METTL10 TRPC4AP ZBTB38
Leg fat percentage (left) 1.29 7 2 6.1 0.72 0.06588 CENPW HMGB1 LPIN3 METTL10 RP5-1115A15.1 RSRC1 SPAST
Arm fat-free mass (left) 1.91 10 6 18.2 -0.60 0.06669 CENPW CTNNB1 DLG5 EXOSC5 HEXIM1 MAPRE1 MASP2 METTL10 TRPC4AP ZBTB38
Number of operations (self-reported) 1.23 1 0 0.0 0.00 1.00000 RP5-1115A15.1
Irritability 1.19 2 1 3.0 0.00 1.00000 LRRC37A2 TMEM258
Ever had prostate specific antigen (PSA) test 1.57 1 0 0.0 0.00 1.00000 ZBTB38
Fractured/broken bones in last 5 years 1.43 1 0 0.0 0.00 1.00000 LRRC37A2
Diastolic blood pressure, automated reading 1.60 8 5 15.2 0.75 0.03104 ATF1 C4orf22 CLIC4 CTNNB1 HEXIM1 RP5-1115A15.1 RSRC1 SRR
Myopia 1.00 1 0 0.0 0.00 1.00000 TMEM258
Vascular/heart problems diagnosed by doctor 1.75 6 1 3.0 -0.58 0.22711 C4orf22 CRTC2 PRDM8 RP3-465N24.5 RP5-1115A15.1 SRR
Cholesterol lowering medication 1.14 1 0 0.0 0.00 1.00000 ARHGEF19
Pain experienced in last month 1.07 1 0 0.0 0.00 1.00000 CENPW
Impedance of whole body 1.25 11 5 15.2 0.29 0.39117 ATF1 CCDC117 CENPW LRRC37A2 MASP2 MPDZ MYEOV PPP2R3A RLTPR SUPT3H WARS2
Leg fat mass (left) 1.15 8 4 12.1 0.23 0.55806 CTNNB1 HMGB1 LGR4 LPIN3 MASP2 METTL10 RP5-1115A15.1 ZBTB38
Arm predicted mass (left) 1.87 9 6 18.2 -0.61 0.08200 CENPW CTNNB1 EXOSC5 HEXIM1 MAPRE1 MASP2 METTL10 TRPC4AP ZBTB38

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 20 0.573 2.27
GTEx Adipose Visceral Omentum 11 0.540 2.61
GTEx Adrenal Gland 13 0.892 2.69
GTEx Artery Aorta 23 0.773 2.57
GTEx Artery Coronary 16 1.352 3.88
GTEx Artery Tibial 19 0.505 2.20
GTEx Brain Caudate basal ganglia 11 1.196 3.44
GTEx Brain Cerebellar Hemisphere 13 0.873 3.03
GTEx Brain Cerebellum 16 0.807 2.66
GTEx Brain Cortex 11 1.063 3.48
GTEx Brain Frontal Cortex BA9 12 1.299 3.50
GTEx Brain Hippocampus 6 1.145 3.97
GTEx Brain Hypothalamus 7 1.186 4.04
GTEx Brain Nucleus accumbens basal ganglia 11 1.272 3.59
GTEx Brain Putamen basal ganglia 7 1.122 3.66
GTEx Breast Mammary Tissue 14 0.709 2.77
GTEx Breast Mammary Tissue (Male) 11 0.922 3.46
GTEx Breast Mammary Tissue (Female) 15 0.912 3.02
GTEx Cells EBV-transformed lymphocytes 14 0.984 3.39
GTEx Cells Transformed fibroblasts 27 0.643 2.36
GTEx Colon Sigmoid 10 0.684 3.00
GTEx Colon Transverse 16 0.775 2.84
GTEx Esophagus Gastroesophageal Junction 16 1.107 3.19
GTEx Esophagus Mucosa 19 0.572 2.52
GTEx Esophagus Muscularis 23 0.712 2.55
GTEx Heart Atrial Appendage 12 0.760 2.85
GTEx Heart Left Ventricle 12 0.784 2.80
GTEx Liver 7 0.976 3.24
GTEx Lung 23 0.801 2.71
GTEx Muscle Skeletal 17 0.588 2.47
GTEx Nerve Tibial 27 0.625 2.38
GTEx Ovary 9 0.991 3.53
GTEx Pancreas 16 0.980 3.07
GTEx Pituitary 12 1.076 2.99
GTEx Prostate 6 0.719 3.13
GTEx Skin Not Sun Exposed Suprapubic 17 0.691 2.59
GTEx Skin Sun Exposed Lower leg 19 0.522 2.50
GTEx Small Intestine Terminal Ileum 4 0.868 3.75
GTEx Spleen 11 0.780 2.85
GTEx Stomach 17 1.169 3.22
GTEx Testis 23 0.729 2.65
GTEx Thyroid 32 0.800 2.47
GTEx Uterus 7 1.235 4.44
GTEx Vagina 8 1.260 3.91
GTEx Whole Blood 12 0.602 2.61
METSIM Adipose 18 0.390 1.81
NTR Blood 11 0.458 2.05
ROSMAP Brain Pre-frontal Cortex 7 0.159 1.71
YFS Blood 17 0.368 1.72
CommonMind Brain Pre-frontal Cortex 30 0.558 2.02
TCGA Breast Tumor 8 1.043 2.64
TCGA Breast Normal 22 0.523 1.89
TCGA Ovarian Tumor 14 0.479 1.94
TCGA Prostate Tumor 18 0.520 2.14