Hub : Genes

HMGB1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.2670 0.0820 0.00210 0.016 NA 0.060 NA 0.025 4.3e-02 NA 3.3e-04 NA 1.5e-02
2 GTEx Breast Mammary Tissue 0.2570 0.0790 0.00170 0.021 NA 0.002 NA 0.032 3.0e-02 NA 2.4e-01 NA 9.1e-03
3 GTEx Muscle Skeletal 0.2078 0.0548 0.00013 0.053 NA 0.066 NA 0.075 6.4e-06 NA 4.4e-07 NA 7.1e-08
4 GTEx Small Intestine Terminal Ileum 0.5780 0.1340 0.00220 0.173 NA -0.011 NA 0.040 1.1e-04 NA 6.9e-01 NA 4.6e-02
5 TCGA Kidney Renal Clear Cell Carcinoma 0.0778 0.0313 0.00220 0.036 0.026 0.025 NA 0.035 5.8e-05 0.00051 7.0e-04 NA 6.9e-05
6 TCGA Pheochromocytoma and Paraganglioma 0.2000 0.0810 0.00880 0.003 0.024 -0.006 NA 0.000 2.4e-01 0.03900 7.1e-01 NA 3.2e-01
7 TCGA Prostate Adenocarcinoma 0.0959 0.0340 0.00015 0.070 0.027 0.049 NA 0.057 8.5e-08 0.00066 7.3e-06 NA 1.4e-06
8 TCGA Thyroid Carcinoma 0.0730 0.0280 0.00130 0.057 0.027 0.030 NA 0.050 2.8e-06 0.00110 6.4e-04 NA 1.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 0.9 2.0 -0.7 -1.1 -1.4 -0.2 -1.1 -0.3 -1.1 -1.0
Bipolar Disorder or Schizophrenia 1.2 3.0 5.0 -1.7 -2.1 -2.2 -0.6 -2.2 -0.6 -1.8 -1.7
Depressed Affect (Nagel 2018) 1.5 3.2 6.2 -2.1 -2.2 -1.3 -0.0 -2.5 -0.8 -2.0 -1.8
Depression (Nagel 2018) 0.7 1.0 4.2 0.9 -0.9 1.0 -0.5 -0.6 -2.0 -0.5 -0.4
Intelligence (Savage-Jansen 2018) 0.3 0.8 1.7 -1.2 -1.3 -0.6 1.3 -0.9 -0.1 -0.5 -0.4
Neuroticism (Nagel 2018) 3.0 7.1 12.1 -2.6 -3.1 -2.1 0.6 -3.5 -1.7 -3.3 -3.1
Schizophrenia (2018) 1.0 2.0 3.9 -1.7 -1.6 -1.6 -0.6 -2.0 -0.4 -1.5 -1.4
Schizophrenia vs Biploar Disorder 0.5 0.7 3.7 0.7 0.4 1.1 -1.9 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 2.4 5.1 7.7 -1.7 -2.8 -1.6 2.5 -2.6 -0.7 -2.7 -2.6
Alzheimer’s Disease (in mother) 0.6 0.7 3.5 -0.1 0.9 0.4 1.9 0.2 0.8 0.4 0.5
Alzheimer’s Disease (in father) 6.0 6.5 10.5 2.6 2.6 2.6 -1.4 3.2 1.9 2.8 2.7
Alzheimer’s Disease (including proxy) 0.5 0.7 1.4 0.6 1.1 0.7 0.4 0.8 1.2 0.8 0.8
Crohns Disease (2017) 0.1 0.3 1.1 -0.9 0.0 -0.2 -1.0 0.2 0.2 0.5 0.6
Irritable Bowel Disease (IBD) 0.2 0.5 2.9 -0.3 -0.1 -0.1 -1.7 0.3 0.3 0.7 0.7
Ulcerative Colitis (UC) 0.4 0.7 4.4 0.1 -0.1 0.3 -2.1 0.3 -0.3 0.6 0.6
Major Depression (MDD) 1.0 1.2 3.7 -1.4 -1.9 0.0 -1.2 -0.8 0.8 -0.8 -0.9
Reaction Time 0.6 1.1 2.2 0.6 0.4 0.9 -1.0 1.3 0.7 1.5 1.5
Verbal and Numeric Reasoning (VNR) 0.2 0.4 1.6 -0.5 -1.2 0.1 0.1 -0.8 -0.9 -0.3 -0.2
Breast Cancer 0.8 1.8 3.2 -0.3 -1.8 -0.9 1.0 -1.7 -0.9 -1.7 -1.7
Ovarian Cancer 0.7 1.0 2.9 -1.1 -1.4 -0.8 -1.7 -0.4 -0.2 -0.7 -0.8
Prostate Cancer 0.4 0.6 2.1 0.2 0.5 1.3 -0.2 0.6 1.4 0.3 0.4
Age at First Birth 0.1 0.1 0.4 0.1 0.3 0.4 -0.1 -0.2 0.1 0.6 0.5
Bipolar Disorder (2011) 0.3 0.3 2.1 -0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 2.6 3.6 7.1 0.8 1.7 1.8 -0.2 2.4 1.6 2.6 2.7
Coronary Artery Disease (CAD) 0.3 0.3 0.7 0.9 0.3 0.8 -0.4 0.7 0.0 0.5 0.3
Crohns Disease (2012) 0.4 0.6 2.0 -1.4 -0.7 -1.3 -0.6 0.0 0.0 0.0 0.0
Mean Putamen Volume 1.9 2.2 5.2 1.8 2.3 1.4 -0.3 1.7 0.1 1.5 1.4
Fasting Glucose 0.2 0.2 0.9 0.4 -0.1 0.4 -0.4 0.5 0.3 0.9 0.5
HbA1C 0.3 0.3 0.6 -0.6 -0.4 -0.4 0.5 0.6 -0.8 0.6 0.5
HDL Cholesterol 0.3 0.5 1.0 0.2 -0.8 -1.0 -0.1 -0.8 -0.7 -0.6 -0.7
LDL Cholesterol 2.6 4.2 7.5 0.7 1.8 2.4 0.4 2.5 1.8 2.5 2.7
Lupus 0.6 0.9 2.6 1.1 0.5 1.1 -0.5 0.4 1.6 0.8 0.8
Neuroticism (2016) 0.3 0.4 0.9 0.4 0.5 -0.9 -0.4 -0.9 0.2 -0.7 -0.7
Primary Biliary Cirrhosis 1.3 1.9 3.4 -0.6 1.4 0.9 -0.7 1.7 1.3 1.9 1.8
Rheumatoid Arthritis 0.6 0.9 4.1 -0.1 0.4 0.2 -2.0 1.1 0.7 0.7 0.6
Schizophrenia (2014) 1.2 2.6 5.1 -1.8 -1.9 -1.7 -0.1 -2.2 -0.8 -1.7 -1.6
Triglycerides 3.4 5.5 9.4 1.7 3.1 3.0 0.3 2.7 1.0 2.8 2.6
Type 2 Diabetes (T2D) (2012) 0.3 0.3 0.9 -0.4 0.2 0.1 -0.7 0.9 0.4 0.8 0.6
Ulcerative Colitis 0.1 0.1 0.7 0.8 -0.5 -0.0 -0.3 -0.0 -0.1 0.1 0.1
Blood Eosinophil Count 0.1 0.6 3.0 -1.7 -0.7 -0.5 -0.2 0.1 -0.8 0.2 0.1
Blood Platelet Count 0.0 0.2 0.7 -0.2 0.3 0.5 0.5 0.8 0.3 0.6 0.5
Blood Red Count 1.3 12.9 21.8 4.5 4.7 3.6 -0.8 3.8 1.4 4.0 3.9
Blood White Count 0.7 5.4 9.1 -1.2 2.0 2.7 -1.9 3.0 2.1 2.7 2.6
Heel T-Score 0.3 2.7 6.7 -1.8 -1.3 -2.6 -0.3 -1.3 -1.2 -1.7 -1.8
BMI 5.5 32.0 54.4 3.1 6.9 6.7 -1.6 7.4 3.1 6.7 6.5
Height 0.5 9.1 18.3 -1.6 -3.5 -3.2 1.0 -4.3 -2.6 -3.4 -3.2
Waist Hip Ratio (WHR) 2.8 12.8 23.6 0.9 4.0 4.1 -0.6 4.0 2.4 4.8 4.9
Systolic Blood Pressure 0.3 1.5 3.4 0.4 1.9 1.6 0.6 1.6 1.5 0.8 0.7
Smoking Status 6.1 14.7 23.3 2.7 3.7 4.7 -0.4 4.5 2.8 4.8 4.8
Allergy or Eczema 0.1 0.3 0.7 0.0 -0.8 0.4 0.3 -0.8 -0.6 -0.6 -0.5
Cardiovascular Disease 1.2 3.8 5.5 1.5 2.2 2.3 0.4 1.9 2.2 2.2 2.2
Hypothyroidism (self reported) 0.2 0.5 1.3 0.8 0.3 0.2 0.3 0.8 -0.5 1.1 1.1
Respiratory disease 0.3 0.6 3.2 -0.2 0.4 0.3 -1.2 -0.2 -1.8 0.3 0.4
Type 2 Diabetes (T2D) (2018) 5.6 10.4 17.1 1.9 3.3 3.6 -1.6 4.1 1.8 4.0 4.0
Lung FEV1/FVC ratio 0.5 2.6 6.1 0.5 1.6 2.1 -0.4 2.5 0.9 1.9 1.8
Lung FVC 0.2 1.1 3.7 0.7 0.3 1.3 1.9 0.8 0.4 1.0 0.9
Neuroticism 2.3 5.6 13.1 -1.7 -2.7 -1.9 0.6 -3.6 -1.2 -3.0 -2.8
Chronotype (morning person) 0.5 1.1 3.2 -0.1 1.0 0.9 -1.8 1.2 -0.0 1.2 1.2
Hair Pigment 0.5 14.3 31.1 3.5 3.5 5.6 -1.4 4.1 3.5 3.8 3.7
Tanning 0.0 0.4 1.7 -1.3 0.6 -0.1 0.9 0.7 0.2 0.2 0.2
Hand grip strength (left) 2.0 5.4 10.0 -3.2 -2.3 -2.1 0.2 -2.4 -2.3 -2.4 -2.5
Number of treatments/medications taken 0.5 0.9 1.7 0.4 1.2 0.6 -0.8 1.0 0.5 1.3 1.3
Average weekly spirits intake 0.4 0.5 2.2 -1.5 -0.0 -0.1 -0.8 0.1 -0.3 0.5 0.6
Sensitivity / hurt feelings 2.4 4.2 8.5 -2.4 -1.4 -2.0 1.3 -2.9 -1.5 -2.3 -2.1
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.9 0.2 -1.0 0.7 -0.2 -0.3 -1.7 -0.6 -0.6
Hearing difficulty/problems: Yes 0.3 0.5 1.3 -0.7 0.1 0.1 0.7 0.0 -0.5 1.0 1.1
Relative age of first facial hair 1.9 3.9 7.0 1.1 -1.9 -1.2 2.2 -2.2 -1.2 -2.5 -2.6
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 5.4 -1.3 -0.4 -1.1 -2.3 -0.5 -1.0 0.2 0.2
Ever used hormone-replacement therapy (HRT) 1.0 1.2 4.0 2.0 0.2 1.0 1.4 0.7 -0.1 1.0 1.1
Ever had hysterectomy (womb removed) 0.3 0.3 1.4 1.2 0.2 0.3 -0.5 0.5 -0.5 0.2 0.2
Systolic blood pressure, automated reading 0.6 1.6 3.6 1.2 1.8 1.9 -0.2 1.6 1.0 0.8 0.8
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.4 -0.2 1.2 1.0 0.4 1.1 0.8 0.5 0.5
Angina 4.5 5.8 9.0 1.2 3.0 2.7 -0.0 2.6 2.7 2.7 2.8
Medication for hormone replacement therapy 1.3 1.5 4.8 -0.7 -1.0 -1.0 2.2 -1.0 -1.5 -0.8 -0.8
Vitamin and mineral supplements 2.4 3.3 4.7 1.6 1.7 2.1 1.8 2.0 0.6 2.2 2.1
Supplements: Zinc 3.8 4.2 9.3 -1.2 -0.9 -1.9 0.2 -3.0 -2.0 -2.8 -2.6
Medication: Co-codamol 3.2 3.7 5.9 1.4 1.9 2.3 -0.8 2.2 1.3 2.4 2.4
Medication: Metformin 6.3 8.9 14.7 1.0 3.2 3.6 -1.0 3.8 1.9 3.7 3.8
Diabetes (father) 1.6 2.0 4.9 1.0 1.3 1.7 1.2 1.1 2.2 1.2 1.2
Diabetes (mother) 0.8 1.1 4.7 -2.2 0.6 -0.1 -1.7 0.4 -0.3 0.3 0.3
Severe depression (siblings) 1.6 1.8 9.9 -3.1 -0.7 -1.6 -0.4 -0.9 -0.2 -0.6 -0.6
Pack years adult smoking proportion 0.6 0.8 4.4 -0.0 0.3 0.1 -2.1 0.7 -0.1 0.9 1.0
Impedance of leg (right) 1.0 5.1 8.9 -1.1 -2.5 -3.0 0.2 -2.8 -1.4 -2.7 -2.7
Leg fat-free mass (left) 1.0 5.5 10.8 1.3 3.3 3.1 -0.9 2.7 0.7 2.6 2.6
Trunk fat percentage 4.6 18.4 28.5 3.1 5.3 5.1 -1.6 5.2 2.5 4.9 4.8
Hand grip strength (right) 0.8 2.3 6.0 -2.5 -1.0 -1.4 -0.0 -1.7 -1.5 -1.4 -1.4
Townsend deprivation index at recruitment 0.5 0.7 2.0 -0.2 -1.3 -0.9 0.2 -0.3 -1.4 -0.5 -0.6
Current tobacco smoking 1.2 2.0 3.7 0.8 1.3 1.3 -0.6 1.7 1.1 1.9 1.9
Average weekly fortified wine intake 0.1 0.2 0.6 -0.7 0.4 -0.7 0.3 -0.1 -0.1 0.2 0.2
Maternal smoking around birth 4.0 5.8 11.7 -0.1 2.4 2.9 -0.2 3.4 1.6 3.0 2.9
Fed-up feelings 0.3 0.5 1.1 -0.6 -1.1 0.6 -0.6 -0.8 -0.5 -0.7 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.4 0.5 -0.5 0.5 -1.0 -0.2 -1.2 -0.3 -0.3
Relative age voice broke 1.0 1.5 3.1 0.7 -1.5 -0.1 1.2 -1.1 -0.6 -1.7 -1.8
Taking other prescription medications 2.7 4.1 9.0 1.8 1.7 2.1 -0.2 1.9 1.2 2.8 3.0
Age when periods started (menarche) 0.1 0.2 0.5 -0.7 0.2 0.0 -0.2 0.3 -0.4 0.6 0.5
Bilateral oophorectomy (both ovaries removed) 3.0 3.5 5.7 2.1 1.7 2.4 0.5 2.1 1.5 2.0 2.0
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 2.1 -1.4 -0.9 -1.2 -0.5 -0.2 -1.0 -0.7 -0.8
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 1.1 -0.4 -0.3 -0.8 0.9 -0.7 0.1 -1.0 -1.1
Qualifications: CSEs or equivalent 0.7 0.9 6.3 -0.4 0.1 -0.5 2.5 -0.3 -0.5 -0.2 -0.2
Serious illness, injury or assault to yourself 1.4 1.6 3.5 -1.4 -1.2 -1.9 0.5 -1.7 -1.1 -1.0 -1.0
High blood pressure 2.4 6.6 11.8 2.5 3.4 3.2 -0.5 2.7 2.3 2.5 2.4
Hayfever, allergic rhinitis or eczema 0.4 0.9 1.8 -0.2 -1.0 -0.6 0.2 -1.3 -1.3 -1.1 -1.0
Multivitamins +/- minerals 3.0 3.8 6.4 -2.0 -1.4 -2.1 -1.1 -2.2 -1.1 -2.5 -2.5
Stomach or abdominal pain in last month 1.0 1.3 2.0 -1.4 -1.4 -0.8 -0.3 -1.2 -1.0 -1.2 -1.2
Supplements: Glucosamine 0.3 0.4 1.6 0.3 0.9 0.5 0.1 0.6 1.3 0.5 0.5
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 1.5 0.2 -1.0 -0.9 0.6 -1.2 0.7 -1.2 -1.1
Medication: Atenolol 4.0 5.0 13.5 3.7 2.9 2.1 1.6 1.1 2.1 1.6 1.8
Medication: Levothyroxine sodium 0.3 0.5 1.9 1.4 -0.7 0.1 0.2 0.5 0.4 0.8 0.9
Sitting height 0.9 6.7 10.4 -2.3 -2.3 -3.0 -0.1 -3.2 -2.5 -3.0 -2.9
Chronic bronchitis/emphysema (father) 0.5 0.6 1.5 1.1 -0.2 0.8 -1.2 1.0 -0.2 0.5 0.5
High blood pressure (mother) 3.3 4.6 8.2 -0.9 -2.5 -1.9 -0.0 -2.0 -2.3 -2.9 -2.9
Body mass index (BMI) 5.2 22.1 35.5 3.0 6.0 5.5 -1.7 5.9 2.6 5.5 5.3
Impedance of leg (left) 1.1 5.5 9.2 -1.0 -2.7 -3.0 -0.2 -2.9 -1.5 -2.8 -2.8
Leg predicted mass (left) 1.1 5.6 10.8 1.3 3.3 3.1 -0.9 2.7 0.7 2.7 2.7
Trunk fat mass 4.5 19.2 30.2 3.0 5.5 5.3 -1.7 5.3 2.3 5.1 5.0
Waist circumference 5.7 21.0 31.8 3.0 5.6 5.4 -1.8 5.6 2.2 5.5 5.4
Number of incorrect matches in round 0.2 0.4 1.1 -0.5 0.3 -0.2 -0.2 0.3 1.0 0.8 0.9
Past tobacco smoking 2.9 5.4 11.2 -1.1 -2.6 -3.4 -0.4 -2.5 -1.2 -2.8 -2.8
Alcohol usually taken with meals 2.5 4.0 6.6 -2.6 -1.8 -1.9 0.1 -2.1 -2.0 -2.3 -2.3
Nervous feelings 2.2 4.1 6.9 -0.7 -2.4 -1.5 2.0 -2.3 -0.8 -2.6 -2.6
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.1 8.1 0.2 -1.2 -0.1 -1.9 -0.9 -2.8 -1.1 -1.1
Hearing difficulty/problems with background noise 0.5 0.8 3.0 0.1 -0.2 0.3 -1.7 -0.2 -1.2 0.8 1.0
Hair/balding pattern: Pattern 2 0.6 0.8 3.1 -1.2 -0.0 0.3 -1.8 0.1 1.1 0.5 0.5
Had menopause 0.7 0.9 3.7 1.9 0.3 -0.3 -1.8 0.2 0.4 0.2 0.1
Had other major operations 0.8 0.9 3.1 -0.5 -1.0 -1.0 -1.8 -0.6 -0.5 -0.9 -0.9
Forced vital capacity (FVC) 0.3 1.2 2.7 -0.6 -1.4 -0.7 1.0 -1.1 -1.6 -0.9 -0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 0.3 -0.6 0.0 -0.4 -0.5 0.5 -0.2 0.3 0.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.4 -0.1 0.0 -0.2 -1.2 -0.4 -0.8 -0.2 -0.1
Qualifications: None of the above 1.2 2.5 5.9 2.4 1.2 1.4 -0.7 1.5 1.9 1.5 1.4
Financial difficulties in last 2 years 1.0 1.4 5.9 -0.4 -0.5 -0.7 -2.4 0.0 -1.8 -0.6 -0.8
Mouth/teeth dental problems 2.1 3.2 7.5 -1.4 -1.6 -2.7 -1.0 -1.4 -0.7 -2.2 -2.3
Heart attack 3.5 4.5 10.6 0.9 3.3 1.9 -1.5 2.1 2.0 2.3 2.3
Allergy 0.3 0.6 2.0 0.1 1.2 -0.3 1.4 0.5 1.0 0.5 0.4
Pain all over the body in last month 1.8 2.0 4.1 0.9 1.0 1.0 0.8 1.6 1.3 2.0 2.0
Diabetes (self-reported) 6.9 10.7 16.7 2.1 3.7 3.4 -1.8 4.1 2.2 3.9 3.9
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.3 0.3 0.0 0.6 -0.5 -0.1 -0.4 -0.1 -0.1
Medication: Ramipril 1.5 1.9 3.5 0.1 1.4 1.6 -0.7 1.9 0.5 1.8 1.7
Medication: Simvastatin 9.1 13.4 21.1 3.2 4.0 3.8 0.8 4.1 2.8 4.6 4.6
Fluid intelligence score 0.1 0.3 1.2 -0.0 -0.2 0.5 0.5 -0.7 -1.1 -0.3 -0.2
Illnesses of siblings 2.3 3.2 7.9 -1.4 -1.7 -1.6 2.8 -1.5 -0.8 -1.8 -1.9
Neuroticism score 1.1 2.3 6.0 -1.1 -1.7 -0.8 0.6 -2.5 -0.8 -1.9 -1.7
Weight 2.3 11.5 21.1 2.2 4.6 4.0 -1.6 4.1 1.3 3.9 3.8
Impedance of arm (right) 1.9 8.7 14.7 -1.5 -3.3 -3.7 1.4 -3.8 -1.3 -3.5 -3.4
Arm fat percentage (right) 4.3 16.8 28.8 2.6 5.4 4.7 -1.1 5.0 2.7 4.7 4.6
Trunk fat-free mass 0.4 2.1 4.5 0.2 2.1 1.8 -0.7 1.6 0.2 1.8 1.8
Hip circumference 1.2 5.1 9.9 2.0 3.2 2.5 -1.5 2.8 0.5 2.3 2.2
Time employed in main current job 0.2 0.2 1.0 0.3 -1.0 0.1 -0.5 -0.3 -0.4 -0.3 -0.2
Alcohol intake versus 10 years previously 2.5 3.7 6.8 2.6 2.6 1.8 -1.0 1.9 1.3 1.9 1.9
Father’s age at death 1.2 1.6 3.9 -2.0 -1.3 -1.5 0.4 -0.9 -1.0 -1.2 -1.3
Worrier / anxious feelings 0.3 0.5 1.7 -0.2 0.3 1.3 1.1 0.4 1.0 0.1 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 6.8 -2.2 -0.4 -0.4 -2.6 -0.9 -1.7 -0.6 -0.5
Falls in the last year 1.8 2.5 4.8 -1.9 -1.3 -1.5 -2.2 -1.2 -1.5 -1.4 -1.4
Hair/balding pattern: Pattern 3 0.7 1.0 3.1 -0.8 -0.6 -1.2 0.4 -1.7 0.5 -1.1 -1.0
Number of live births 0.6 0.8 3.6 -0.9 0.0 -0.3 -0.9 0.8 1.9 0.6 0.6
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 3.1 -0.9 -1.0 -0.2 0.6 -0.5 -1.8 -0.7 -0.7
Pulse rate 0.9 1.5 2.7 0.9 0.7 1.4 1.0 1.6 0.1 1.6 1.6
Happiness 2.9 3.5 6.0 -2.2 -2.4 -1.6 0.1 -2.0 -1.7 -2.0 -2.0
Noisy workplace 2.0 2.5 6.4 1.5 1.4 1.8 -1.1 2.5 0.4 1.5 1.4
Qualifications: A levels/AS levels or equivalent 3.1 6.9 9.7 -2.1 -2.4 -3.1 0.7 -3.1 -2.9 -3.0 -3.0
Serious illness, injury or assault of a close relative in last 2 years 1.8 2.1 3.3 -1.7 -1.2 -1.8 1.8 -1.4 -1.3 -1.0 -1.0
Mouth/teeth dental problems: Dentures 2.3 3.9 9.8 1.1 1.2 3.1 -0.3 1.9 1.7 2.3 2.5
Asthma 0.1 0.3 1.1 0.3 0.5 0.2 -1.0 0.2 -0.5 0.4 0.6
Medication: Ibuprofen (e.g. Nurofen) 1.9 2.4 7.2 -0.5 -1.5 -0.8 -2.7 -1.2 -1.8 -1.3 -1.3
Medication: Cholesterol lowering 9.2 14.2 21.5 2.8 3.7 4.1 0.9 4.4 3.5 4.6 4.6
Depression (self-reported) 1.1 1.3 2.9 -0.9 -1.2 -1.4 -0.6 -1.3 -1.7 -0.7 -0.8
Medication: Lansoprazole 0.4 0.4 2.6 -1.6 -0.5 0.2 -0.4 -0.1 -0.7 -0.2 -0.1
Prospective memory result 0.4 0.4 2.0 1.0 0.3 0.6 -1.4 0.3 -0.1 -0.1 -0.2
Lung cancer (father) 0.8 0.9 5.3 -0.2 -2.3 -0.1 -0.4 0.2 -0.6 -0.7 -0.8
Illnesses of mother 0.6 0.7 1.2 -0.3 0.8 0.9 0.4 1.1 1.0 1.1 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.7 4.0 -1.3 -1.8 -0.9 0.1 -1.1 -2.0 -1.2 -1.2
Pulse wave Arterial Stiffness index 0.4 0.4 1.1 -0.3 -1.0 0.6 0.1 -0.7 -0.7 -0.7 -0.6
Impedance of arm (left) 2.1 9.8 17.2 -1.5 -3.5 -3.8 1.2 -4.2 -1.5 -3.8 -3.7
Arm fat mass (right) 4.6 18.8 30.8 2.7 5.5 5.1 -1.4 5.2 2.5 5.1 5.0
Trunk predicted mass 0.4 2.2 4.6 0.2 2.1 1.8 -0.7 1.7 0.3 1.8 1.8
Standing height 0.5 4.6 8.5 -1.6 -2.1 -2.4 0.2 -2.9 -2.1 -2.4 -2.3
Length of working week for main job 1.5 1.7 3.8 1.9 1.2 1.1 -0.1 1.1 0.5 1.6 1.7
Exposure to tobacco smoke at home 0.4 0.5 1.5 0.5 0.4 -0.7 -0.1 -0.3 -1.2 -0.8 -0.9
Breastfed as a baby 0.9 1.2 3.5 0.3 -1.0 -1.1 0.6 -1.2 -1.9 -1.0 -1.0
Tense / ‘highly strung’ 0.6 1.0 1.7 -0.6 -1.0 -1.1 -0.4 -1.3 -1.1 -0.9 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 3.3 5.0 8.7 -2.9 -1.8 -1.7 -1.2 -2.3 -2.7 -2.4 -2.3
Hair/balding pattern: Pattern 4 11.1 27.0 43.5 3.1 4.7 6.6 -3.2 6.4 2.6 6.5 6.4
Birth weight of first child 0.3 0.6 1.4 0.0 -1.2 -0.3 -1.2 -0.9 -0.2 -0.9 -0.8
Peak expiratory flow (PEF) 0.3 0.7 2.3 -1.5 -0.8 -0.1 -0.2 -0.2 -1.3 -0.5 -0.5
Pulse wave reflection index 1.0 1.2 2.7 -0.6 -1.2 -0.3 -0.4 -1.3 -1.6 -1.3 -1.3
Ever highly irritable/argumentative for 2 days 0.4 0.5 2.2 -1.1 -0.5 -0.3 -1.5 -0.1 -0.5 0.2 0.1
Loud music exposure frequency 0.4 0.4 1.2 -0.9 -0.8 -0.4 -1.1 -0.6 -0.1 -0.4 -0.3
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 5.8 0.1 0.2 -1.2 1.3 -0.6 -2.4 -0.9 -1.0
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.5 0.7 0.8 1.2 -0.3 0.6 0.4 0.9 0.9
Blood clot in the leg (DVT) 0.5 0.6 2.4 0.4 -1.1 -0.1 -1.5 -0.2 -0.1 -0.7 -0.7
Medication: Paracetamol 0.5 0.8 4.3 -0.6 -0.5 0.5 -2.1 -0.3 -0.8 -0.5 -0.6
Headache pain in last month 1.0 1.7 2.7 -0.1 -1.0 -1.1 -1.1 -1.6 -1.5 -1.6 -1.6
Medication for cholesterol, blood pressure or diabetes 3.8 6.2 9.5 -1.7 -2.6 -2.7 0.4 -2.9 -2.3 -3.1 -3.1
Glaucoma (self-reported) 1.4 1.7 3.5 0.5 0.9 1.4 1.9 1.5 0.9 1.4 1.4
Gout (self-reported) 6.3 8.7 15.0 1.4 3.4 2.9 -1.2 2.8 3.1 3.7 3.9
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 0.9 0.6 -0.0 0.0 0.9 0.4 -0.7 0.6 0.6
Medication: Amlodipine 0.5 0.7 2.3 0.0 1.1 0.5 1.5 0.6 1.1 0.6 0.6
Medication: Ventolin 100micrograms inhaler 1.0 1.3 2.2 -0.6 -1.0 -1.2 1.0 -1.5 -0.9 -1.4 -1.3
Birth weight 1.6 3.4 6.5 -1.3 -2.5 -1.8 0.3 -2.0 -1.3 -2.3 -2.3
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.5 0.3 -0.3 -0.3 -0.7 -0.0 -0.1 0.2 0.2
High blood pressure (siblings) 0.8 1.2 6.3 -0.5 -0.6 -0.7 -2.5 -0.9 -0.8 -0.7 -0.6
Forced vital capacity (FVC), Best measure 0.5 2.0 4.6 -1.1 -2.0 -1.2 0.2 -1.4 -2.1 -1.2 -1.1
Body fat percentage 5.0 19.6 32.1 3.4 5.7 5.1 -1.9 5.4 2.6 5.0 4.9
Leg fat percentage (right) 5.5 20.0 35.9 3.2 6.0 4.9 -2.0 5.5 2.7 5.0 4.8
Arm fat-free mass (right) 1.0 5.1 8.0 1.2 2.8 2.8 -1.9 2.6 0.3 2.6 2.6
Exposure to tobacco smoke outside home 0.4 0.6 1.1 -0.1 0.4 -1.0 -1.0 -0.6 -0.6 -0.9 -0.9
Comparative body size at age 10 0.1 0.3 0.8 -0.7 -0.9 -0.7 0.1 -0.5 0.3 -0.1 -0.1
Number of full brothers 0.1 0.2 0.6 0.4 -0.5 -0.1 0.8 0.5 0.0 -0.1 -0.2
Worry too long after embarrassment 0.7 1.1 2.4 -0.5 -1.1 -0.5 0.6 -1.5 -0.2 -1.6 -1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 2.6 3.4 7.2 -2.2 -1.2 -2.7 0.0 -2.1 -1.7 -1.8 -1.9
Wheeze or whistling in the chest in last year 0.3 0.5 1.9 0.7 0.2 0.7 -1.4 -0.2 0.7 0.4 0.5
Number of children fathered 2.1 2.3 4.6 -0.0 0.9 1.8 0.4 2.1 1.0 2.1 2.1
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 1.3 0.1 -1.0 -1.1 1.0 -0.7 -1.1 -1.0 -1.1
Age at first live birth 0.5 0.8 5.8 0.7 0.4 -0.3 2.4 0.0 -0.1 -0.1 -0.1
Pulse wave peak to peak time 0.2 0.3 0.8 -0.0 0.8 -0.9 -0.1 0.3 0.5 0.4 0.3
Health satisfaction 0.8 1.0 5.3 -1.6 -0.4 -0.2 -2.3 -0.0 -0.6 -0.1 -0.1
Shortness of breath walking on level ground 0.9 1.0 3.4 -0.4 1.8 0.9 -0.4 0.7 -0.2 1.2 1.3
Qualifications: College or University degree 0.2 0.7 1.3 -1.0 -0.7 -1.1 0.0 -0.8 -1.2 -0.6 -0.6
Eye problems/disorders: None of the above 0.3 0.3 0.8 0.3 -0.2 -0.9 0.4 -0.6 -0.6 -0.6 -0.6
Mouth/teeth dental problems: Loose teeth 1.4 1.7 3.6 -1.2 -1.1 -1.1 1.9 -1.4 -1.9 -0.7 -0.6
Emphysema/chronic bronchitis 3.1 3.5 7.3 -2.1 -2.7 -1.0 -1.5 -2.0 -1.7 -1.8 -1.7
Medication for pain relief, constipation, heartburn 1.4 2.3 7.4 0.1 -0.8 -2.0 2.7 -1.7 -0.2 -1.4 -1.2
Neck or shoulder pain in last month 3.1 4.4 16.7 -0.6 -1.5 -2.1 -4.1 -1.4 -1.6 -1.9 -1.9
Medication: Blood pressure 1.7 3.0 6.3 1.7 2.5 1.6 -0.7 1.7 1.8 1.7 1.7
Angina (self-reported) 4.9 6.5 10.5 1.4 3.2 2.9 0.1 2.7 2.6 2.9 2.9
Migraine (self-reported) 3.3 4.0 6.5 -2.0 -1.8 -1.9 -0.8 -2.6 -1.9 -2.4 -2.3
Medication: Ibuprofen 0.6 0.7 4.8 0.0 -0.4 0.3 -2.2 -0.2 -0.9 -0.2 -0.2
Medication: Allopurinol 3.3 4.3 8.5 1.1 2.1 2.3 -1.5 1.9 1.4 2.7 2.9
Medication: Omeprazole 0.4 0.5 1.8 0.4 0.0 0.6 -1.3 0.8 -0.2 0.7 0.6
Medication: Seretide 50 evohaler 1.3 1.5 3.0 1.4 1.0 0.8 0.7 1.3 0.1 1.7 1.7
Mean time to correctly identify matches 3.2 6.2 11.2 2.1 2.1 2.5 -0.5 2.9 1.9 3.3 3.4
Heart disease (mother) 0.2 0.3 0.7 0.4 0.4 0.2 -0.5 0.4 0.7 0.8 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.7 -0.5 1.3 0.1 -0.0 0.7 1.0 1.0 1.2
Whole body fat mass 4.7 19.7 32.3 3.1 5.7 5.3 -1.8 5.4 2.3 5.1 5.0
Leg fat mass (right) 5.2 20.2 35.1 3.2 5.9 5.2 -2.1 5.4 2.4 5.0 4.9
Arm predicted mass (right) 1.1 5.4 8.7 1.3 3.0 2.9 -1.6 2.6 0.4 2.7 2.7
Pulse rate, automated reading 1.6 5.0 7.3 2.1 2.5 2.3 -0.8 2.7 2.2 2.5 2.4
Alcohol intake frequency. 0.7 1.6 4.0 -0.6 -1.3 -1.5 -0.5 -1.6 -2.0 -0.9 -0.8
Comparative height size at age 10 0.9 5.2 11.0 -1.6 -2.5 -2.5 -0.8 -3.3 -0.6 -2.8 -2.6
Number of full sisters 0.7 0.8 2.6 -0.4 0.9 0.4 -1.6 0.7 -0.0 1.1 1.1
Suffer from ‘nerves’ 2.7 4.2 6.9 -1.6 -1.5 -1.2 2.5 -2.3 -1.6 -2.6 -2.6
Overall health rating 0.3 0.7 2.7 0.2 0.6 0.8 -1.6 0.6 -0.5 0.8 0.8
Chest pain or discomfort 0.4 0.5 1.7 -0.4 1.0 0.4 -1.3 -0.3 -1.0 0.3 0.3
Had major operations 0.3 0.4 1.1 -0.7 -1.1 -0.3 0.7 -0.1 -0.8 -0.2 -0.2
Age at last live birth 0.9 1.3 5.2 -0.6 -0.6 -1.0 2.3 -1.1 -0.4 -1.1 -1.1
Family relationship satisfaction 1.9 2.4 4.3 -2.1 -1.9 -1.3 0.3 -1.8 -1.5 -1.5 -1.4
Leg pain on walking 1.4 1.8 4.2 -2.0 -0.9 -0.8 -1.7 -1.3 -0.6 -1.4 -1.4
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 2.6 -1.1 -1.2 -0.7 0.6 -0.9 -1.6 -1.3 -1.3
Commuting to job workplace: Car/motor vehicle 4.1 4.7 7.6 2.1 2.4 1.8 -1.3 2.6 1.1 2.8 2.7
Illness, injury, bereavement, stress in last 2 years 1.6 2.0 2.5 1.5 1.3 1.6 -0.5 1.6 1.6 1.5 1.4
Medication: Aspirin 4.0 5.2 8.1 0.5 2.7 2.0 -1.4 2.6 2.3 2.8 2.8
Supplements: Vitamin C 1.8 2.2 4.5 -1.1 -1.8 -1.3 -2.1 -1.5 -0.4 -1.5 -1.4
Knee pain experienced in last month 0.5 0.9 1.9 -1.4 -1.2 -0.5 -1.1 -0.6 0.3 -0.9 -0.9
Hypertension (Self-reported) 2.4 6.8 10.7 2.8 3.2 3.3 -0.4 2.6 2.3 2.6 2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.3 -0.6 0.3 0.3 -0.5 -0.1 -0.0 0.2 0.3
Illnesses of father: Heart disease 0.1 0.2 0.7 -0.4 0.1 -0.3 -0.9 0.5 -0.0 0.5 0.5
Illnesses of siblings: Diabetes 2.5 3.1 6.2 0.1 1.6 1.5 -1.2 2.5 1.2 2.3 2.3
Smoking status: Previous 3.1 4.7 11.1 1.1 2.6 3.3 0.5 2.2 1.0 2.5 2.5
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 2.6 -1.6 -1.5 -0.4 -0.7 -0.8 -1.6 -0.9 -0.9
Whole body fat-free mass 0.7 3.8 7.3 0.8 2.7 2.5 -0.9 2.2 0.3 2.3 2.3
Leg fat-free mass (right) 0.8 4.4 8.0 1.2 2.8 2.8 -0.9 2.3 0.6 2.4 2.4
Arm fat percentage (left) 4.3 17.1 29.5 2.6 5.4 4.8 -1.5 5.0 2.6 4.7 4.6
Average weekly red wine intake 0.2 0.3 1.6 0.5 -1.3 0.1 0.1 -0.1 -0.5 -0.0 -0.0
Handedness (chirality/laterality): Left-handed 0.5 0.6 3.0 0.3 0.2 -0.8 1.7 -0.4 -0.1 -0.6 -0.7
Mood swings 1.4 2.5 4.4 -2.1 -1.9 -1.6 0.9 -2.0 -0.9 -1.4 -1.3
Loneliness, isolation 0.1 0.2 0.6 0.2 -0.6 -0.1 -0.8 -0.7 -0.0 -0.3 -0.3
Long-standing illness, disability or infirmity 0.8 1.2 3.4 -0.2 1.1 0.7 -0.3 1.2 -0.3 1.8 1.9
Ever had bowel cancer screening 0.6 0.7 3.6 -0.5 -0.9 0.4 1.9 -0.2 0.4 -0.4 -0.4
Diabetes diagnosed by doctor 6.4 10.5 17.6 1.6 3.6 3.4 -1.6 4.2 2.2 4.0 4.0
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 5.2 -1.3 -0.6 -1.0 -2.3 -1.0 0.5 -0.8 -0.8
Friendships satisfaction 1.1 1.3 3.3 -1.5 -0.9 -1.1 0.1 -1.1 -1.8 -1.0 -1.0
Qualifications: nursing, teaching 0.9 1.4 7.2 -1.0 0.1 -0.6 -2.7 -0.1 -1.5 -0.5 -0.5
Commuting to job workplace: Walk 0.3 0.3 2.1 0.0 -0.4 0.0 1.4 0.0 0.3 -0.3 -0.4
Eye problems/disorders: Cataract 0.7 0.8 1.8 0.8 0.6 0.6 1.3 0.1 1.2 0.9 0.9
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 1.1 -0.5 1.0 0.2 0.2 -0.3 0.5 0.2 0.2
Medication for cholesterol 0.4 0.5 2.1 0.4 -1.2 -0.2 -1.5 -0.2 0.0 -0.6 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.1 -0.6 -0.4 -1.1 -0.0 -0.9 0.2 -0.3 -0.2
Back pain experienced in last month 0.1 0.1 0.5 0.5 -0.2 0.2 0.2 -0.1 -0.7 0.3 0.3
Mineral and other dietary supplements 1.9 2.5 4.7 0.9 1.2 2.2 1.3 2.2 0.6 1.9 1.8
Breast cancer (self-reported) 0.7 0.9 1.8 -0.9 -0.9 -1.3 -1.2 -1.2 -0.0 -0.7 -0.7
Asthma (self-reported) 0.2 0.3 1.4 -0.1 0.2 0.1 -1.2 -0.0 -1.0 0.2 0.4
Osteoporosis (self-reported) 1.4 1.7 4.6 0.1 -1.0 -1.4 -0.3 -2.2 -1.5 -1.3 -1.3
Osteoarthritis (self-reported) 3.5 4.6 6.9 1.5 1.7 2.5 1.4 2.6 1.8 2.6 2.6
Medication: Aspirin 6.1 7.9 11.7 1.0 3.4 2.8 -0.9 3.2 2.9 3.4 3.4
Medication: Gliclazide 5.0 5.7 10.6 1.4 3.3 2.2 -1.1 2.8 1.3 2.9 3.0
Illnesses of father: None of the above (group 1) 0.5 0.7 1.2 -1.1 -1.1 -0.8 0.3 -1.0 -0.0 -0.8 -0.8
Smoking status: Current 1.3 2.0 3.8 1.1 1.2 1.3 -0.1 1.8 0.9 2.0 1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.1 0.6 0.1 0.2 0.4 -0.3 0.8 0.1 0.2 0.0
Whole body water mass 0.6 3.5 6.9 0.7 2.6 2.4 -0.9 2.1 0.3 2.2 2.2
Leg predicted mass (right) 0.9 4.6 8.2 1.2 2.9 2.8 -0.9 2.4 0.6 2.4 2.5
Arm fat mass (left) 4.4 18.1 30.4 2.6 5.5 5.1 -1.7 5.1 2.4 4.9 4.8
Number of self-reported non-cancer illnesses 1.0 1.7 2.9 1.2 1.2 1.7 -0.6 1.3 0.6 1.6 1.6
Average weekly champagne plus white wine intake 1.5 2.1 3.7 -1.1 -1.7 -1.2 1.9 -1.2 -0.6 -1.6 -1.7
Miserableness 1.6 2.9 5.8 -2.4 -1.7 -1.5 -0.1 -1.9 -2.0 -1.5 -1.4
Guilty feelings 0.9 1.4 2.5 0.2 -1.5 -0.7 0.8 -1.5 -1.1 -1.6 -1.5
Wears glasses or contact lenses 1.4 1.6 2.9 -0.0 1.3 1.3 -0.2 1.4 1.7 1.5 1.6
Ever taken oral contraceptive pill 0.8 0.9 3.7 -1.9 0.2 -0.4 -1.0 0.4 -1.4 0.2 0.2
Hearing aid user 0.6 0.7 1.8 -0.4 1.3 0.4 0.8 1.1 -0.2 0.8 0.8
Mother’s age at death 0.1 0.1 0.4 0.6 -0.2 0.3 -0.2 -0.0 0.5 0.0 0.1
Financial situation satisfaction 0.2 0.3 0.8 -0.7 0.4 0.5 -0.9 0.1 -0.1 -0.4 -0.5
Tinnitus: Yes, now most or all of the time 0.8 1.0 2.0 1.4 0.9 1.1 -0.3 1.4 0.7 0.8 0.7
Commuting to job workplace: Public transport 0.1 0.2 0.9 -0.9 -0.0 -0.1 0.6 0.2 0.1 0.2 0.2
Eye problems/disorders: Glaucoma 1.1 1.3 2.5 0.5 0.7 1.6 -0.1 1.4 0.5 1.6 1.5
Medication: Blood pressure 0.5 0.9 1.9 0.5 1.4 1.3 -0.4 1.0 0.5 1.1 1.1
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.4 0.2 0.3 0.8 -1.6 0.6 0.6 0.9 0.9
Supplements: Fish oil (including cod liver oil) 1.8 2.4 4.0 -1.1 -1.4 -2.0 -1.2 -2.0 -0.2 -1.8 -1.8
High cholesterol (Self-reported) 2.9 5.1 8.2 2.0 2.6 2.0 1.6 2.1 1.8 2.8 2.9
Medication: Bendroflumethiazide 0.9 1.3 8.8 -0.3 1.0 -0.3 -3.0 -0.3 -0.1 0.4 0.5
Medication: Paracetamol 0.7 1.1 5.9 -0.2 0.5 1.6 -2.4 0.6 -0.3 0.3 0.2
Medication: Lisinopril 0.3 0.4 1.3 1.0 0.2 -0.4 1.2 -0.6 -0.0 0.0 0.2
Medication: Atorvastatin 1.3 1.6 2.7 0.1 1.5 1.6 0.7 1.6 0.6 1.5 1.5
Illnesses of father: High blood pressure 1.7 2.0 5.3 0.9 -0.6 -1.1 0.8 -1.9 -2.3 -1.5 -1.5
Alcohol drinker status: Never 0.5 0.6 1.3 -0.8 -1.2 -0.7 0.3 -0.7 -0.2 -1.0 -1.0
Ever smoked 1.8 3.2 7.2 0.9 2.1 2.7 0.2 1.8 0.7 2.2 2.2
Basal metabolic rate 1.0 5.5 10.5 1.1 3.2 2.9 -1.2 2.7 0.6 2.7 2.7
Leg fat percentage (left) 5.7 20.8 34.9 3.4 5.9 5.1 -2.3 5.5 2.8 5.1 5.0
Arm fat-free mass (left) 1.1 5.5 9.4 1.3 3.1 2.8 -1.5 2.7 0.6 2.7 2.7
Number of operations (self-reported) 1.7 2.5 4.8 -1.4 -2.2 -1.2 0.4 -2.0 -1.2 -1.9 -1.8
Average weekly beer plus cider intake 8.2 11.8 17.0 3.0 4.1 3.9 0.5 4.1 1.9 4.1 4.0
Irritability 0.8 1.3 3.4 -0.3 -0.9 -0.2 -1.8 -1.1 -1.7 -0.9 -0.8
Risk taking 1.1 1.6 2.7 -1.2 1.3 1.0 -1.2 0.9 1.1 1.5 1.7
Ever had prostate specific antigen (PSA) test 0.8 0.9 5.9 -0.9 0.1 0.4 2.4 0.6 0.0 0.5 0.4
Fractured/broken bones in last 5 years 0.4 0.6 3.5 0.0 -0.5 0.3 -1.9 -0.4 -0.3 -0.4 -0.4
Age started oral contraceptive pill 0.4 0.5 2.6 1.6 0.6 -0.3 -0.4 0.6 0.5 0.3 0.2
Diastolic blood pressure, automated reading 1.4 4.3 7.6 1.5 2.6 2.8 -1.7 2.5 0.8 1.9 1.9
Ever depressed for a whole week 0.2 0.3 0.9 -0.7 -0.0 -0.2 -0.8 -0.5 -0.9 -0.3 -0.3
Unable to work because of sickness or disability 0.1 0.2 1.0 -0.1 0.4 -0.1 1.0 0.3 -0.3 0.3 0.2
Commuting to job workplace: Cycle 0.4 0.5 1.7 0.0 -0.6 0.2 0.9 -0.2 -1.3 -0.7 -0.8
Myopia 0.3 0.5 2.3 -0.0 -0.6 -0.4 1.5 -0.3 0.1 -0.6 -0.6
Vascular/heart problems diagnosed by doctor 3.4 9.4 14.1 -3.0 -3.8 -3.6 0.7 -3.3 -2.9 -3.1 -3.0
Cholesterol lowering medication 2.6 3.9 7.1 0.7 2.5 1.5 0.6 2.4 1.2 2.7 2.6
Medication: Omeprazole (e.g. Zanprol) 0.2 0.2 1.0 -0.3 -0.3 0.4 -1.0 0.5 -0.5 0.3 0.2
Pain experienced in last month 0.5 0.8 2.6 0.3 0.7 0.9 1.6 1.1 0.4 0.7 0.7
Supplements: Calcium 1.6 1.8 3.3 -1.8 -1.3 -1.1 1.2 -1.6 -1.0 -1.3 -1.2
Basal cell carcinoma (self-reported) 0.3 0.3 1.1 -1.1 0.7 -0.5 -0.5 0.2 -0.6 -0.1 -0.1
Heart attack/myocardial infarction (self-reported) 3.7 4.7 10.4 0.8 3.2 1.9 -1.6 2.2 2.2 2.3 2.4
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 3.0 0.2 -1.3 -0.1 -1.7 -0.3 -0.2 -0.7 -0.7
Heart disease (siblings) 1.6 1.9 2.9 1.1 1.2 1.2 -1.6 1.2 1.3 1.7 1.7
Alcohol drinker status: Previous 1.1 1.2 2.8 0.3 -1.2 -1.7 0.8 -1.3 -1.4 -0.7 -0.6
Pack years of smoking 0.9 1.3 3.8 0.4 0.7 0.6 -1.9 1.2 0.3 1.4 1.5
Impedance of whole body 1.8 9.1 14.9 -1.2 -3.6 -3.7 0.5 -3.9 -1.8 -3.7 -3.6
Leg fat mass (left) 5.2 20.4 34.0 3.3 5.8 5.3 -2.2 5.4 2.4 5.1 5.0
Arm predicted mass (left) 1.0 5.1 9.0 1.1 3.0 2.8 -1.5 2.6 0.6 2.6 2.6