TWAS hub - ARPP21

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Prostate Adenocarcinoma	0.0504	0.0335	0.00400	0.019	0.009	0.012	NA	0.013	3.9e-03	3.1e-02	1.7e-02	NA	0.01400
2	TCGA	Skin Cutaneous Melanoma	0.2660	0.1040	0.00012	0.181	0.147	0.160	NA	0.145	1.4e-05	9.8e-05	4.5e-05	NA	0.00011

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Worry too long after embarrassment	18.2	30.5	40.7	6.4	-4.5
Neuroticism	12.8	30.8	42.6	6.5	-4.4
Neuroticism score	11.7	24.4	31.5	5.6	-4.1
Neuroticism (Nagel 2018)	11.6	27.2	39.0	6.2	-3.9
Alcohol usually taken with meals	10.8	17.5	22.8	3.5	-4.8
Worrier / anxious feelings	10.5	19.8	23.0	4.8	-4.1
Guilty feelings	8.2	12.3	17.4	4.2	-2.7
Unable to work because of sickness or disability	8.0	10.4	14.2	-3.8	2.5
Miserableness	7.3	12.6	16.6	4.1	-2.9
Depressed Affect (Nagel 2018)	7.0	14.6	22.1	4.7	-2.7
Worry (Nagel 2018)	6.7	14.2	20.4	4.5	-2.8
Irritability	6.6	11.1	13.9	3.7	-2.9
Number of full brothers	6.5	8.1	13.5	-3.7	1.7
Neuroticism (2016)	6.2	8.9	11.3	3.4	-2.6
Hand grip strength (left)	5.8	15.2	23.9	4.9	-2.5
Number of children fathered	5.5	6.2	8.5	2.0	-2.9
Arm fat percentage (right)	5.3	21.0	35.0	-5.9	2.6
Hand grip strength (right)	5.2	14.1	20.4	4.5	-2.8
Mood swings	5.1	9.2	12.7	3.6	-2.4
Tense / ‘highly strung’	5.0	8.2	12.9	3.6	-1.9
Nervous feelings	4.9	9.1	12.1	3.5	-2.5
Leg fat percentage (left)	4.9	17.6	31.7	-5.6	1.9
Waist circumference	4.8	17.5	29.7	-5.4	2.3
Arm fat percentage (left)	4.8	19.3	33.2	-5.8	2.3
Body mass index (BMI)	4.7	20.0	33.8	-5.8	2.5
Leg fat percentage (right)	4.7	17.2	31.4	-5.6	1.7
BMI	4.5	26.1	41.5	-6.4	3.3
Townsend deprivation index at recruitment	4.4	6.1	9.4	-1.7	3.1
Suffer from ‘nerves’	4.4	6.9	8.2	2.9	-2.4
Arm fat mass (right)	4.1	16.8	28.7	-5.4	2.2
Body fat percentage	4.0	15.9	28.7	-5.4	1.8
Leg fat mass (right)	3.8	14.9	27.7	-5.3	1.4
Leg fat mass (left)	3.8	14.7	27.4	-5.2	1.4
Supplements: Zinc	3.7	4.1	4.1	-2.0	2.0
Mouth/teeth dental problems: Loose teeth	3.6	4.2	5.4	-1.7	2.3
Arm fat mass (left)	3.6	14.9	26.5	-5.2	1.8
Pulse rate	3.5	6.0	8.7	-1.8	3.0
Maternal smoking around birth	3.4	5.0	5.4	-2.3	2.1
Whole body fat mass	3.4	14.1	26.1	-5.1	1.5
Supplements: Fish oil (including cod liver oil)	3.2	4.2	6.2	2.5	-1.5
Trunk fat percentage	3.1	12.4	22.0	-4.7	1.6
Osteoarthritis (self-reported)	3.1	4.1	7.3	-2.7	0.9
Supplements: Calcium	3.1	3.4	3.8	-1.7	1.9
Chronotype (morning person)	3.0	6.9	8.5	2.3	-2.9
Average weekly beer plus cider intake	2.9	4.1	5.5	-2.3	1.7
Trunk fat mass	2.8	11.8	21.6	-4.7	1.4
Time employed in main current job	2.5	2.9	4.1	2.0	-1.3
Exposure to tobacco smoke at home	2.5	2.8	5.2	-2.3	-0.6
Mouth/teeth dental problems: Bleeding gums	2.5	3.3	5.0	-2.2	1.2
Age at first live birth	2.5	4.5	5.1	2.3	-2.0
Mineral and other dietary supplements	2.5	3.4	5.1	-2.3	1.3
Alzheimer’s Disease (including proxy)	2.4	3.4	6.2	0.8	-2.5
Peak expiratory flow (PEF)	2.4	5.6	7.1	2.0	-2.7
Average weekly red wine intake	2.4	3.5	4.5	2.1	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	6.6	0.7	-2.6
Ever taken oral contraceptive pill	2.3	2.6	3.4	-1.8	1.3
Risk taking	2.3	3.4	4.5	-2.1	1.5
Ovarian Cancer	2.2	3.0	3.2	1.7	-1.8
Medication: Ibuprofen	2.2	2.6	2.9	-1.7	1.5
Age at last live birth	2.2	3.1	3.3	1.7	-1.8
Illnesses of father: None of the above (group 1)	2.2	2.7	5.1	2.3	0.6
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	4.5	-2.1	-0.7
Chronic bronchitis/emphysema (father)	2.1	2.4	4.2	-2.0	0.8
Medication: Lansoprazole	2.1	2.4	2.4	-1.5	1.5
Alcohol drinker status: Previous	2.1	2.4	2.8	-1.4	1.7
Fed-up feelings	2.0	3.6	5.4	2.3	-1.3
Medication: Seretide 50 evohaler	2.0	2.3	4.5	0.3	-2.1
Smoking status: Current	2.0	3.2	4.8	-2.2	1.2
HDL Cholesterol	1.9	3.2	4.8	2.2	-1.2
Ulcerative Colitis	1.9	2.7	4.1	2.0	-1.1
Sensitivity / hurt feelings	1.9	3.2	4.5	1.4	-2.1
Hearing difficulty/problems: Yes	1.9	2.8	3.3	1.8	-1.5
Current tobacco smoking	1.9	3.0	4.4	-2.1	1.3
Pulse wave peak to peak time	1.9	2.2	3.7	0.8	-1.9
Shortness of breath walking on level ground	1.9	2.3	2.3	-1.5	1.5
Myopia	1.9	2.7	5.4	-0.1	2.3
Qualifications: CSEs or equivalent	1.8	2.4	2.5	-1.5	1.6
Weight	1.8	9.1	17.0	-4.1	1.1
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	3.3	-1.1	1.8
Pulse wave Arterial Stiffness index	1.8	2.1	3.6	-0.8	1.9
Ever highly irritable/argumentative for 2 days	1.8	2.1	2.5	1.6	-1.3
Medication: Ventolin 100micrograms inhaler	1.8	2.3	2.6	1.4	-1.6
Family relationship satisfaction	1.8	2.2	2.9	-1.7	1.2
Knee pain experienced in last month	1.8	2.8	3.6	-1.9	1.4
Ever used hormone-replacement therapy (HRT)	1.7	2.2	4.3	-0.1	-2.1
Number of incorrect matches in round	1.7	2.9	5.4	2.3	-0.6
Hair/balding pattern: Pattern 2	1.7	2.2	3.6	-0.9	-1.9
Depression (self-reported)	1.7	2.1	3.3	1.8	-0.9
Commuting to job workplace: Car/motor vehicle	1.7	2.0	3.2	-1.8	0.9
Qualifications: nursing, teaching	1.7	2.7	4.4	2.1	-1.0
Average weekly champagne plus white wine intake	1.7	2.3	2.8	1.3	-1.7
Illnesses of siblings	1.6	2.3	3.8	2.0	-0.8
Waist Hip Ratio (WHR)	1.5	6.6	9.2	-3.0	2.0
Medication: Simvastatin	1.5	2.2	4.3	-2.1	0.3
Hip circumference	1.5	6.7	12.0	-3.5	1.2
Health satisfaction	1.5	2.0	2.0	-1.4	1.4
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	2.5	1.0	1.6
Handedness (chirality/laterality): Left-handed	1.5	1.8	2.4	1.5	-1.1
Friendships satisfaction	1.5	1.8	2.2	-1.2	1.5
Commuting to job workplace: Public transport	1.5	1.8	2.0	1.3	-1.4
Ever had hysterectomy (womb removed)	1.4	1.6	3.1	-1.8	0.4
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.9	1.7	-0.2
Supplements: Glucosamine	1.4	1.8	2.5	1.6	-1.0
Forced vital capacity (FVC)	1.4	5.4	6.7	2.6	-2.0
Alcohol intake frequency.	1.4	3.3	5.1	-1.2	2.3
Relative age voice broke	1.3	2.1	2.8	1.1	-1.7
Heart attack	1.3	1.7	2.0	-1.4	1.2
Glaucoma (self-reported)	1.3	1.5	2.2	-0.9	1.5
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.2	-1.5	1.0
Schizophrenia vs Biploar Disorder	1.2	1.6	1.9	1.4	-1.1
Reaction Time	1.2	2.3	4.2	-0.6	2.0
Breast Cancer	1.2	2.9	4.7	1.0	-2.2
Primary Biliary Cirrhosis	1.2	1.7	2.5	1.6	-0.9
Allergy or Eczema	1.2	3.2	4.0	2.0	-1.5
Illnesses of father: Heart disease	1.2	1.7	2.8	-1.7	-0.8
Age started oral contraceptive pill	1.2	1.5	2.9	1.7	-0.3
Heart disease (siblings)	1.2	1.5	1.8	-1.1	1.3
Alzheimer’s Disease (in father)	1.1	1.2	2.3	0.2	-1.5
Age at First Birth	1.1	1.6	3.0	1.7	-0.3
HbA1C	1.1	1.3	2.5	1.6	0.1
Average weekly spirits intake	1.1	1.3	1.9	-1.4	-0.9
Pain all over the body in last month	1.1	1.2	1.2	-1.1	1.1
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	4.4	1.7	-2.1
Hair/balding pattern: Pattern 4	1.1	2.6	3.8	2.0	-1.2
Wheeze or whistling in the chest in last year	1.1	2.0	2.9	-1.7	1.0
Overall health rating	1.1	2.3	4.5	-2.1	0.1
Osteoporosis (self-reported)	1.1	1.3	1.6	1.3	-1.0
Mother’s age at death	1.1	1.4	1.4	1.1	-1.2
Number of operations (self-reported)	1.1	1.7	2.4	-1.0	-1.6
Intelligence (Savage-Jansen 2018)	1.0	3.0	6.0	-2.4	0.1
Rheumatoid Arthritis	1.0	1.4	2.2	1.5	-0.7
Falls in the last year	1.0	1.3	2.4	1.6	-0.4
Medication: Omeprazole	1.0	1.2	1.4	-1.0	1.2
Mean time to correctly identify matches	1.0	1.9	3.5	-0.6	1.9
Had major operations	1.0	1.2	1.3	-1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.4	-1.2	-1.0
Commuting to job workplace: Walk	1.0	1.1	1.2	1.0	-1.1
Number of self-reported non-cancer illnesses	1.0	1.7	2.1	-1.5	1.1
Triglycerides	0.9	1.4	1.5	-1.2	1.1
Allergy	0.9	2.0	2.8	-1.7	1.1
Number of full sisters	0.9	1.1	1.2	-1.0	1.1
Wears glasses or contact lenses	0.9	1.0	2.0	1.4	0.0
Hearing aid user	0.9	1.0	1.8	0.4	-1.3
Eye problems/disorders: Glaucoma	0.9	1.0	1.3	-1.1	0.9
Medication: Blood pressure	0.9	1.6	2.5	-1.6	0.9
Medication: Bendroflumethiazide	0.9	1.4	2.4	-1.5	-0.6
Alcohol drinker status: Never	0.9	1.0	2.0	-0.3	1.4
Basal cell carcinoma (self-reported)	0.9	1.0	1.8	1.3	-0.5
Heart attack/myocardial infarction (self-reported)	0.9	1.1	1.6	-1.3	0.8
Impedance of whole body	0.9	4.4	6.9	2.6	-1.4
Major Depression (MDD)	0.8	1.0	1.8	-1.3	0.5
Bipolar Disorder (2011)	0.8	0.8	1.1	1.1	-0.7
Impedance of leg (right)	0.8	3.9	5.2	2.3	-1.6
Hayfever, allergic rhinitis or eczema	0.8	1.7	3.0	1.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	1.5	1.2	-1.0
Happiness	0.8	0.9	1.6	0.5	-1.2
Lung cancer (father)	0.8	1.0	1.5	-0.7	1.2
Birth weight of first child	0.8	1.4	1.8	-1.0	1.4
Back pain experienced in last month	0.8	1.2	2.2	-1.5	0.4
Medication: Gliclazide	0.8	0.9	1.1	0.8	-1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.1	1.7	-1.3	-0.7
Body Mass Index (BMI) (2010)	0.7	1.0	1.5	-1.2	0.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.5	-0.2	1.2
Medication for hormone replacement therapy	0.7	0.7	1.2	-1.1	-0.5
Medication: Co-codamol	0.7	0.8	1.3	-1.1	0.5
Taking other prescription medications	0.7	1.1	2.1	-1.4	-0.4
Impedance of leg (left)	0.7	3.3	4.7	2.2	-1.4
Mouth/teeth dental problems	0.7	1.0	1.6	1.3	0.6
Diabetes (self-reported)	0.7	1.1	1.9	-1.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	2.4	1.4	-1.6
Standing height	0.7	7.4	8.4	2.9	-2.5
Heart disease (mother)	0.7	0.9	1.6	-0.4	-1.3
Ever smoked	0.7	1.3	1.4	1.1	-1.2
Verbal and Numeric Reasoning (VNR)	0.6	1.5	3.0	-1.7	0.2
Lung FVC	0.6	2.9	5.2	2.3	-0.8
Leg fat-free mass (left)	0.6	3.3	6.2	-2.5	0.7
Leg predicted mass (left)	0.6	3.3	6.0	-2.5	0.7
Hearing difficulty/problems with background noise	0.6	0.9	1.3	-0.8	1.1
Qualifications: None of the above	0.6	1.2	2.0	-0.7	1.4
Financial difficulties in last 2 years	0.6	0.8	1.4	-0.5	-1.2
Medication: Ramipril	0.6	0.7	0.8	-0.9	0.9
Impedance of arm (right)	0.6	2.6	5.1	2.2	-0.3
Father’s age at death	0.6	0.8	1.1	0.8	-1.0
Medication: Cholesterol lowering	0.6	0.9	1.7	-1.3	-0.0
Impedance of arm (left)	0.6	2.8	5.1	2.3	-0.8
Forced vital capacity (FVC), Best measure	0.6	2.3	3.1	1.8	-1.2
Medication: Aspirin	0.6	0.8	1.6	-1.3	-0.2
Supplements: Vitamin C	0.6	0.7	1.4	-0.2	1.2
Commuting to job workplace: Cycle	0.6	0.7	1.0	1.0	0.6
Pack years of smoking	0.6	0.8	1.1	-1.1	0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.5	0.8	-0.9	0.5
Lung FEV1/FVC ratio	0.5	2.7	5.1	-2.3	0.5
Medication: Metformin	0.5	0.7	0.7	-0.8	0.8
Severe depression (siblings)	0.5	0.6	0.8	0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.7	-1.3	-0.7
Had other major operations	0.5	0.6	1.2	-0.2	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.3	-0.9	-1.1
Fluid intelligence score	0.5	1.0	2.0	-1.4	0.2
Noisy workplace	0.5	0.6	0.6	-0.8	0.8
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	1.8	-1.3	0.2
Comparative body size at age 10	0.5	1.5	2.7	1.6	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.1	0.2	-1.0
Loneliness, isolation	0.5	0.7	0.9	0.9	0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.3	-0.5	-1.1
Medication: Aspirin	0.5	0.6	1.2	-1.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.2	1.1	-0.9
Leg predicted mass (right)	0.5	2.5	4.6	-2.1	0.7
Illnesses of father: High blood pressure	0.5	0.6	0.9	-1.0	-0.6
Basal metabolic rate	0.5	2.8	5.5	-2.3	0.3
Alzheimer’s Disease (in mother)	0.4	0.4	0.8	-0.2	-0.9
Ulcerative Colitis (UC)	0.4	0.8	1.3	0.6	1.1
LDL Cholesterol	0.4	0.7	1.3	-0.3	1.1
Blood White Count	0.4	3.1	5.9	-2.4	0.5
Smoking Status	0.4	1.0	1.9	-1.4	0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.1	-1.1	-0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.9	0.9	-0.5
Pack years adult smoking proportion	0.4	0.6	0.7	-0.8	0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.0	1.0	-0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.0	0.5	1.0
Gout (self-reported)	0.4	0.6	1.0	1.0	-0.3
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.5	-0.6	0.7
Exposure to tobacco smoke outside home	0.4	0.5	0.8	-0.4	-0.9
Medication for pain relief, constipation, heartburn	0.4	0.6	1.2	1.1	-0.2
Hypertension (Self-reported)	0.4	1.2	2.1	-1.4	0.6
Leg fat-free mass (right)	0.4	2.4	4.4	-2.1	0.6
Medication for cholesterol	0.4	0.6	1.1	1.1	-0.2
Financial situation satisfaction	0.4	0.5	0.7	0.9	-0.5
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.5	-0.6	0.7
Arm fat-free mass (left)	0.4	1.8	3.6	-1.9	0.2
Fractured/broken bones in last 5 years	0.4	0.5	0.9	0.9	-0.3
Diastolic blood pressure, automated reading	0.4	1.1	2.2	-1.5	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.5	1.2	-0.7
Coronary Artery Disease (CAD)	0.3	0.4	0.5	0.7	0.4
Schizophrenia (2014)	0.3	0.7	1.2	1.1	-0.4
Tanning	0.3	3.8	7.6	-2.8	-0.1
Vitamin and mineral supplements	0.3	0.4	0.5	-0.7	-0.6
Diabetes (mother)	0.3	0.4	0.6	-0.7	-0.5
Average weekly fortified wine intake	0.3	0.3	0.5	0.7	-0.3
Age when periods started (menarche)	0.3	0.7	1.1	-0.5	1.0
High blood pressure	0.3	0.8	1.3	-1.2	0.6
Stomach or abdominal pain in last month	0.3	0.4	0.7	-0.8	-0.3
Sitting height	0.3	2.2	3.2	1.1	-1.8
Illnesses of mother	0.3	0.4	0.6	0.8	-0.4
Qualifications: College or University degree	0.3	1.0	1.7	1.3	-0.5
Emphysema/chronic bronchitis	0.3	0.4	0.7	-0.8	-0.0
Medication: Allopurinol	0.3	0.4	0.6	0.8	-0.4
Chest pain or discomfort	0.3	0.4	0.6	-0.8	0.5
Diabetes diagnosed by doctor	0.3	0.5	1.0	-1.0	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	-0.8	0.1
High cholesterol (Self-reported)	0.3	0.4	0.9	0.1	-0.9
Medication: Lisinopril	0.3	0.4	0.7	0.0	-0.8
Ever depressed for a whole week	0.3	0.4	0.6	-0.4	-0.8
Arm predicted mass (left)	0.3	1.4	2.7	-1.6	-0.1
Depression (Nagel 2018)	0.2	0.3	0.4	0.6	-0.4
Irritable Bowel Disease (IBD)	0.2	0.5	0.8	0.5	0.9
Prostate Cancer	0.2	0.2	0.3	0.6	0.3
Mean Putamen Volume	0.2	0.2	0.4	-0.7	0.1
Lupus	0.2	0.4	0.6	-0.8	-0.4
Height	0.2	4.8	6.4	1.8	-2.5
Hypothyroidism (self reported)	0.2	0.4	0.5	-0.6	-0.7
Number of treatments/medications taken	0.2	0.3	0.5	-0.7	-0.3
Relative age of first facial hair	0.2	0.4	0.6	0.4	-0.7
Serious illness, injury or assault to yourself	0.2	0.2	0.2	-0.5	0.5
Had menopause	0.2	0.3	0.3	-0.5	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.5	0.6	-0.7
Mouth/teeth dental problems: Dentures	0.2	0.3	0.5	-0.7	-0.3
Asthma	0.2	0.4	0.7	-0.8	0.3
Breastfed as a baby	0.2	0.2	0.5	-0.7	0.0
Loud music exposure frequency	0.2	0.2	0.3	0.3	-0.6
Headache pain in last month	0.2	0.4	0.5	-0.5	0.7
High blood pressure (siblings)	0.2	0.3	0.4	-0.7	-0.3
Arm fat-free mass (right)	0.2	1.3	2.3	-1.5	-0.5
Neck or shoulder pain in last month	0.2	0.3	0.5	-0.5	0.7
Medication: Blood pressure	0.2	0.3	0.4	-0.5	-0.7
Arm predicted mass (right)	0.2	1.2	2.3	-1.5	-0.4
Leg pain on walking	0.2	0.2	0.3	0.2	0.6
Illnesses of siblings: Diabetes	0.2	0.3	0.5	-0.7	-0.4
Whole body fat-free mass	0.2	1.3	2.7	-1.6	0.0
Asthma (self-reported)	0.2	0.4	0.5	-0.7	0.6
Whole body water mass	0.2	1.3	2.6	-1.6	0.1
Medication: Paracetamol	0.2	0.3	0.6	-0.2	0.8
Medication: Atorvastatin	0.2	0.3	0.5	0.7	0.3
Cholesterol lowering medication	0.2	0.3	0.4	-0.4	0.6
Schizophrenia (2018)	0.1	0.2	0.3	0.5	0.3
Crohns Disease (2012)	0.1	0.2	0.4	0.6	0.0
Fasting Glucose	0.1	0.1	0.2	0.5	-0.0
Blood Eosinophil Count	0.1	1.0	1.3	0.9	-1.1
Blood Platelet Count	0.1	1.2	1.5	1.2	-0.9
Blood Red Count	0.1	1.0	1.9	-1.4	-0.2
Heel T-Score	0.1	1.1	1.5	0.8	-1.2
Systolic Blood Pressure	0.1	0.5	0.9	-0.4	-1.0
Cardiovascular Disease	0.1	0.3	0.6	-0.3	-0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	-0.4	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.4	-0.6	0.1
Diabetes (father)	0.1	0.1	0.1	-0.4	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.3	0.4
Past tobacco smoking	0.1	0.2	0.2	-0.3	0.5
Trunk fat-free mass	0.1	0.7	1.3	-1.2	-0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.2	-0.5	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.2	0.5	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.3	-0.1	-0.5
Trunk predicted mass	0.1	0.8	1.5	-1.2	-0.2
Pulse wave reflection index	0.1	0.1	0.1	-0.3	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	-0.3	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.1	-0.5
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.2	-0.5
Migraine (self-reported)	0.1	0.1	0.2	0.5	0.2
Smoking status: Previous	0.1	0.1	0.1	0.1	-0.4
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.3	-0.4
Ever had bowel cancer screening	0.1	0.1	0.1	0.2	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.1	0.3	-0.3
Pain experienced in last month	0.1	0.1	0.2	-0.5	-0.3
Bipolar Disorder (2018)	0.0	0.0	0.1	-0.2	0.1
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	0.3	0.2
Crohns Disease (2017)	0.0	0.0	0.0	0.1	0.2
Respiratory disease	0.0	0.1	0.1	-0.4	0.0
Hair Pigment	0.0	0.3	0.4	0.5	-0.7
Angina	0.0	0.0	0.1	0.3	-0.1
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.3	-0.0
Multivitamins +/- minerals	0.0	0.1	0.1	-0.2	0.3
Medication: Atenolol	0.0	0.1	0.1	0.2	-0.2
Medication: Levothyroxine sodium	0.0	0.1	0.1	-0.3	0.1
High blood pressure (mother)	0.0	0.0	0.0	-0.1	-0.0
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.1	0.2	-0.1
Hair/balding pattern: Pattern 3	0.0	0.1	0.1	0.3	0.1
Number of live births	0.0	0.0	0.0	-0.0	0.0
Prospective memory result	0.0	0.0	0.1	0.3	0.1
Length of working week for main job	0.0	0.0	0.0	0.2	0.1
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.2	-0.1
Medication: Paracetamol	0.0	0.1	0.1	-0.1	0.3
Medication: Amlodipine	0.0	0.0	0.0	-0.0	0.1
Birth weight	0.0	0.1	0.1	0.4	-0.2
Angina (self-reported)	0.0	0.0	0.1	0.1	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.1	0.1	-0.1	-0.3
Pulse rate, automated reading	0.0	0.0	0.0	-0.1	0.2
Comparative height size at age 10	0.0	0.2	0.3	0.5	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.0	-0.2	0.1
Eye problems/disorders: Cataract	0.0	0.0	0.1	-0.3	0.1
Breast cancer (self-reported)	0.0	0.1	0.1	0.1	-0.3
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.2	0.1
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.1	0.3	0.1

Hub : Genes

ARPP21

Models

Trait associations