Hub : Traits :

Hand grip strength (left)

1261 significantly associated models · 252 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 9576675 11137778 1 1 7.1e-09 1.7e-08 1.0e+00 100 KIF1B
2 1 22712328 24201643 1 1 2.0e-07 1.6e-07 1.0e+00 100 LUZP1
3 1 149815323 151227371 3 1 2.1e-07 3.9e-07 1.0e+00 100 ADAMTSL4
4 1 183961643 185416670 1 1 1.7e-07 3.8e-07 1.0e-01 90 EDEM3
5 1 204888754 206329620 6 2 1.9e-14 7.5e-14 4.3e-01 99 ELK4 NUCKS1
6 1 227217340 228663659 2 1 8.0e-12 1.9e-13 3.4e-03 84 JMJD4
7 2 23604114 25889403 7 8 4.5e-15 2.3e-14 NaN NaN ADCY3 CENPO DNAJC27 NCOA1 RP11-443B20.1 TP53I3
8 2 43417083 44920960 1 1 4.6e-09 2.0e-10 1.3e-02 85 LRPPRC
9 2 67709195 69180661 2 1 7.7e-08 9.0e-08 1.0e+00 100 RP11-474G23.2
10 2 69978290 71471456 1 2 4.4e-16 5.1e-14 3.7e-02 92 TGFA
11 2 134513621 137435625 6 1 1.2e-13 3.4e-12 2.0e-01 96 LOC100129961
12 2 217456567 220226393 2 2 3.3e-07 3.5e-08 8.0e-03 77 BCS1L DIRC3
13 3 52047421 53860103 5 1 6.1e-10 1.6e-09 1.0e+00 100 RFT1
14 3 140350567 142017527 2 1 8.0e-10 1.7e-11 1.0e+00 100 ZBTB38
15 4 644410 2058475 2 1 1.9e-08 1.2e-06 1.1e-02 73 CRIPAK
16 4 17104059 18533844 2 2 5.2e-17 4.9e-19 2.5e-02 94 DCAF16 NCAPG
17 4 101634693 103687208 1 1 3.7e-07 6.1e-17 7.6e-14 20 BANK1
18 5 129885843 132839137 13 6 9.1e-15 7.7e-14 1.0e+00 100 AC034220.3 CDC42SE2 P4HA2 PDLIM4 RAPGEF6 SLC22A4
19 6 1967240 3450266 1 1 3.3e-08 4.1e-07 1.0e+00 100 MYLK4
20 6 12595275 13990267 1 1 2.4e-07 4.1e-07 1.0e+00 100 RP1-257A7.5
21 6 80374293 81763771 1 1 1.4e-07 3.3e-06 4.6e-02 82 RP11-250B2.6
22 6 129638583 131163098 2 1 4.9e-19 2.1e-16 1.0e+00 100 RP11-73O6.3
23 6 154878398 156330580 2 1 5.8e-08 2.8e-08 4.5e-03 74 TFB1M
24 7 38907533 40309402 1 1 3.3e-07 5.3e-12 1.5e-07 42 C7orf36
25 7 99220083 100932330 11 1 2.6e-09 1.4e-07 1.0e+00 100 PILRA
26 7 119935156 121630503 1 1 5.1e-08 2.3e-08 4.4e-03 74 C7orf58
27 7 149847287 151252618 1 1 1.6e-07 4.0e-14 4.3e-08 48 AOC1
28 9 126844856 128643415 5 1 2.0e-10 9.5e-10 1.0e+00 100 GOLGA1
29 10 78845149 80383574 2 1 1.9e-07 1.7e-08 3.0e-02 85 RP13-39P12.3
30 10 80443273 81901722 1 1 1.9e-09 1.5e-07 1.3e-02 77 ZCCHC24
31 10 102416555 105694301 13 8 3.1e-14 1.4e-10 NaN NaN ACTR1A ARL3 BTRC CYP17A1-AS1 SUFU TMEM180
32 11 1250488 2640824 1 1 3.6e-07 1.9e-06 6.1e-06 10 TNNT3
33 11 46622392 48485877 10 1 1.8e-15 1.3e-12 4.6e-04 76 Y_RNA
34 11 65670510 67856510 2 4 1.4e-15 8.8e-15 1.0e+00 100 CCS RAD9A
35 11 73024914 75075866 4 3 3.7e-11 2.5e-17 4.0e-02 94 C2CD3 POLD3 PPME1
36 11 76602665 78216992 2 1 6.5e-13 1.2e-10 4.6e-01 99 AQP11
37 12 14220891 16190627 8 2 9.0e-26 4.3e-25 1.8e-01 98 ERP27 MGP
38 12 47671905 49061511 1 1 6.9e-08 3.2e-07 1.0e-01 90 TMEM106C
39 12 105939816 107367439 1 1 2.1e-07 1.0e-06 6.9e-01 99 CKAP4
40 12 123424071 125270773 5 1 8.6e-08 4.9e-08 3.9e-02 86 RP11-214K3.24
41 13 50592874 52109040 1 2 4.2e-08 1.2e-16 4.8e-08 57 DLEU7
42 14 74245607 76089054 4 2 2.5e-08 3.2e-08 3.3e-01 97 NPC2 YLPM1
43 15 50944589 52392509 1 1 2.8e-08 1.9e-09 1.3e-02 83 GLDN
44 15 73524629 75038482 2 3 6.6e-13 9.4e-13 1.1e-05 62 LOXL1-AS1 PML
45 15 77023336 78474476 1 1 3.1e-09 2.7e-09 1.3e-02 82 HMG20A
46 16 1381714 2952423 4 3 1.4e-12 5.6e-14 6.5e-02 94 MLST8 PKD1 TSC2
47 16 3969463 5510848 2 1 2.0e-07 2.9e-07 4.6e-01 98 ZNF500
48 16 19022448 20596558 3 1 1.1e-07 4.6e-07 1.2e-04 42 AC002550.5
49 16 29412503 31026427 9 1 1.1e-09 3.0e-09 2.7e-01 97 YPEL3
50 16 69062879 70840490 4 1 3.1e-13 1.6e-12 2.2e-02 90 NOB1
51 16 89013848 90172696 1 1 2.9e-08 3.9e-06 1.6e-04 33 CHMP1A
52 17 36211659 37644854 2 1 6.7e-15 9.6e-15 1.0e+00 100 PSMB3
53 17 41946180 47357969 37 5 1.4e-13 2.4e-13 3.8e-01 99 ACBD4 ADAM11 FZD2 HOXB2 RP11-259G18.1
54 17 61106371 62694738 5 1 7.6e-10 5.0e-10 1.0e+00 100 CD79B
55 18 45873080 47686517 1 1 2.2e-10 2.5e-12 5.9e-04 76 DYM
56 18 52209411 54028036 1 1 1.6e-07 1.0e-14 1.0e-10 30 TCF4
57 19 36309321 39002725 6 2 9.1e-08 3.5e-08 7.3e-03 76 ZNF260 ZNF573
58 20 9925555 11347455 1 1 1.4e-07 7.0e-06 3.3e-06 -7 JAG1
59 20 32254831 35226873 27 6 3.8e-27 1.9e-28 NaN NaN GGT7 MAP1LC3A RP3-477O4.16 UQCC1
60 20 46838455 48410403 2 1 5.7e-08 2.2e-08 1.3e-01 93 ARFGEF2
61 22 38386787 39794434 2 1 2.2e-07 3.7e-05 1.9e-04 18 TOMM22
62 22 41720697 43226599 2 1 1.5e-07 4.0e-07 4.5e-01 98 CYP2D6

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 0.99 1 0 0.0 0.00 1.0e+00 YPEL3
Crohns Disease (2017) 3.55 11 8 24.2 0.26 3.9e-01 AC034220.3 ADCY3 CENPO DNAJC27 P4HA2 PDLIM4 RAPGEF6 RFT1 RP11-443B20.1 SLC22A4 ZBTB38
Irritable Bowel Disease (IBD) 3.04 11 7 21.2 -0.06 8.3e-01 AC034220.3 ADAMTSL4 ADCY3 CENPO DNAJC27 NCOA1 P4HA2 PDLIM4 RAPGEF6 RP11-443B20.1 SLC22A4
Ulcerative Colitis (UC) 1.85 1 0 0.0 0.00 1.0e+00 SLC22A4
Major Depression (MDD) 1.26 1 0 0.0 0.00 1.0e+00 TCF4
Reaction Time 2.01 6 0 0.0 0.07 8.8e-01 ACTR1A ADCY3 ARFGEF2 ARL3 NUCKS1 TMEM180
Verbal and Numeric Reasoning (VNR) 1.94 7 2 6.1 -0.36 4.2e-01 ADCY3 ARFGEF2 CYP2D6 DCAF16 LRPPRC NCAPG Y_RNA
Breast Cancer 2.82 12 9 27.3 0.27 3.5e-01 ADCY3 CENPO DNAJC27 P4HA2 PILRA RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 SLC22A4 TGFA TNNT3 ZBTB38
Ovarian Cancer 1.41 2 2 6.1 0.00 1.0e+00 HOXB2 RP11-259G18.1
Prostate Cancer 2.27 4 0 0.0 0.42 5.8e-01 ACTR1A NUCKS1 SUFU TMEM180
Body Mass Index (BMI) (2010) 2.57 6 3 9.1 0.55 1.6e-01 AC002550.5 ADCY3 DNAJC27 GGT7 RP11-443B20.1 Y_RNA
Coronary Artery Disease (CAD) 2.17 2 1 3.0 0.00 1.0e+00 RP11-214K3.24 RP1-257A7.5
Crohns Disease (2012) 2.93 6 3 9.1 -0.77 7.5e-02 AC034220.3 ADCY3 P4HA2 PDLIM4 SLC22A4 ZNF260
HDL Cholesterol 1.80 3 2 6.1 0.00 1.0e+00 AC002550.5 RP11-214K3.24 Y_RNA
Neuroticism 1.47 2 0 0.0 0.00 1.0e+00 TCF4 YLPM1
Primary Biliary Cirrhosis 1.22 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Schizophrenia 1.46 2 1 3.0 0.00 1.0e+00 ARL3 YPEL3
Triglycerides 1.13 1 1 3.0 0.00 1.0e+00 RP11-214K3.24
Ulcerative Colitis 2.17 1 0 0.0 0.00 1.0e+00 ACTR1A
Blood Eosinophil Count 3.86 17 13 39.4 0.66 3.1e-03 AC034220.3 ACBD4 ADCY3 CENPO DNAJC27 LUZP1 NOB1 P4HA2 PDLIM4 RAPGEF6 RFT1 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 SLC22A4 YPEL3 ZNF260
Blood Platelet Count 2.40 29 23 69.7 0.37 4.6e-02 AC002550.5 AC034220.3 ACTR1A ADAM11 AQP11 BCS1L BTRC CYP17A1-AS1 DCAF16 DYM EDEM3 ELK4 FZD2 HMG20A HOXB2 KIF1B NCAPG P4HA2 PDLIM4 PILRA RAPGEF6 SLC22A4 SUFU TGFA TMEM106C TMEM180 YLPM1 Y_RNA ZCCHC24
Blood Red Count 2.22 20 15 45.5 0.22 3.2e-01 ACBD4 AOC1 BCS1L CCS CD79B ELK4 HOXB2 KIF1B LOC100129961 MAP1LC3A NOB1 RAD9A RP11-214K3.24 RP11-259G18.1 RP11-73O6.3 TMEM106C TP53I3 YPEL3 ZBTB38 ZNF500
Blood White Count 2.52 27 19 57.6 0.42 2.3e-02 AC034220.3 ACTR1A ADAMTSL4 ADCY3 CENPO CYP17A1-AS1 DCAF16 EDEM3 GGT7 MLST8 NCAPG NOB1 P4HA2 PDLIM4 PILRA PKD1 RAPGEF6 RP11-214K3.24 RP11-73O6.3 RP13-39P12.3 SLC22A4 SUFU TMEM180 TP53I3 TSC2 YPEL3 Y_RNA
Heel T-Score 4.41 33 28 84.8 0.13 4.6e-01 AC002550.5 ADCY3 C7orf58 CHMP1A CRIPAK CYP2D6 DCAF16 DIRC3 DLEU7 FZD2 GGT7 GLDN JAG1 JMJD4 KIF1B MAP1LC3A MGP MLST8 NCAPG PILRA PKD1 PSMB3 RFT1 RP11-214K3.24 RP11-259G18.1 RP11-73O6.3 TMEM106C TOMM22 TSC2 YLPM1 YPEL3 ZBTB38 ZCCHC24
BMI 4.48 23 14 42.4 0.55 2.7e-03 AC002550.5 ADCY3 ARFGEF2 ARL3 BANK1 CCS CENPO DNAJC27 DYM EDEM3 GGT7 LOC100129961 LOXL1-AS1 MLST8 NCOA1 NOB1 PML RFT1 RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 YPEL3 Y_RNA
Height 13.17 77 72 218.2 -0.86 1.3e-26 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 ADCY3 AOC1 AQP11 ARFGEF2 ARL3 BCS1L BTRC C7orf58 CCS CD79B CDC42SE2 CENPO CHMP1A CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DNAJC27 DYM EDEM3 ELK4 FZD2 GGT7 GLDN JAG1 JMJD4 KIF1B LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NOB1 NPC2 NUCKS1 P4HA2 PDLIM4 PKD1 PML POLD3 PPME1 PSMB3 RAD9A RAPGEF6 RFT1 RP11-214K3.24 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TCF4 TFB1M TMEM106C TMEM180 TP53I3 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF260 ZNF500 ZNF573
Waist Hip Ratio (WHR) 3.20 15 12 36.4 0.18 5.0e-01 ADCY3 C7orf58 CD79B DYM GGT7 JMJD4 PKD1 PSMB3 RAD9A RP11-214K3.24 RP11-250B2.6 RP11-259G18.1 RP11-73O6.3 UQCC1 ZBTB38
Systolic Blood Pressure 2.32 21 13 39.4 -0.19 3.8e-01 ACBD4 ADAM11 ADCY3 ARFGEF2 ARL3 BANK1 CENPO DCAF16 DNAJC27 HOXB2 LOC100129961 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP1-257A7.5 RP3-477O4.16 TMEM106C TNNT3 UQCC1 Y_RNA ZNF500
Smoking Status 2.46 7 4 12.1 -0.67 4.7e-02 ACTR1A ARL3 CYP17A1-AS1 NOB1 RP11-259G18.1 SUFU TMEM180
Allergy or Eczema 2.44 11 5 15.2 0.58 4.9e-02 ACTR1A ARL3 CYP17A1-AS1 LUZP1 MAP1LC3A P4HA2 SLC22A4 SUFU TMEM180 TOMM22 ZBTB38
Cardiovascular Disease 1.35 8 2 6.1 0.82 1.2e-02 DCAF16 EDEM3 NCAPG RP11-474G23.2 SLC22A4 TMEM106C TNNT3 TSC2
Respiratory disease 2.24 5 4 12.1 0.98 2.3e-03 AC034220.3 CCS P4HA2 PDLIM4 SLC22A4
Type 2 Diabetes (T2D) 1.59 3 0 0.0 0.00 1.0e+00 CYP17A1-AS1 NOB1 Y_RNA
Lung FEV1/FVC ratio 2.21 21 14 42.4 0.03 9.0e-01 AC034220.3 ADCY3 CENPO DNAJC27 ELK4 GGT7 HOXB2 LOXL1-AS1 MAP1LC3A NCOA1 NUCKS1 P4HA2 PDLIM4 PSMB3 RP11-259G18.1 RP11-443B20.1 SLC22A4 UQCC1 YLPM1 YPEL3 ZBTB38
Lung FVC 3.33 29 18 54.5 -0.05 7.9e-01 ADAM11 ADAMTSL4 AOC1 ARFGEF2 CD79B DCAF16 DLEU7 FZD2 GLDN HOXB2 JAG1 LOC100129961 LOXL1-AS1 MAP1LC3A NCAPG NOB1 NPC2 NUCKS1 P4HA2 RAD9A RP11-259G18.1 RP11-73O6.3 RP3-477O4.16 SLC22A4 TCF4 TFB1M TMEM106C UQCC1 ZBTB38
Neuroticism 2.25 5 3 9.1 -0.05 9.4e-01 CYP17A1-AS1 RP11-259G18.1 TCF4 YLPM1 Y_RNA
Chronotype (morning person) 1.74 2 1 3.0 0.00 1.0e+00 ADAMTSL4 CRIPAK
Hair Pigment 3.40 16 11 33.3 0.33 1.7e-01 ADCY3 CHMP1A DIRC3 DNAJC27 ELK4 GGT7 KIF1B LOC100129961 MAP1LC3A NUCKS1 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 UQCC1 ZBTB38
Tanning 2.47 10 7 21.2 -0.70 5.4e-03 ADAMTSL4 ADCY3 CHMP1A DNAJC27 ELK4 GGT7 MAP1LC3A RP11-443B20.1 RP3-477O4.16 UQCC1
Number of treatments/medications taken 2.10 5 0 0.0 -0.77 7.2e-02 CCS DCAF16 ELK4 P4HA2 YLPM1
Sensitivity / hurt feelings 1.57 1 1 3.0 0.00 1.0e+00 RP11-259G18.1
Frequency of depressed mood in last 2 weeks 1.44 2 0 0.0 0.00 1.0e+00 ARFGEF2 RP11-259G18.1
Relative age of first facial hair 2.07 4 1 3.0 -0.59 4.1e-01 CHMP1A GGT7 RP11-259G18.1 ZBTB38
Systolic blood pressure, automated reading 1.89 9 3 9.1 -0.31 4.2e-01 ACBD4 ADCY3 DCAF16 EDEM3 LOC100129961 RP11-259G18.1 RP11-474G23.2 RP1-257A7.5 TNNT3
Angina 1.80 2 1 3.0 0.00 1.0e+00 GGT7 RP1-257A7.5
Medication: Metformin 1.87 1 0 0.0 0.00 1.0e+00 Y_RNA
Impedance of leg (right) 3.22 24 16 48.5 -0.24 1.9e-01 AC002550.5 ACBD4 ADAM11 ADCY3 AOC1 CCS CD79B CDC42SE2 CHMP1A DLEU7 DNAJC27 GGT7 HOXB2 LOXL1-AS1 NUCKS1 RAD9A RAPGEF6 RFT1 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 TMEM106C UQCC1 YPEL3
Leg fat-free mass (left) 7.12 44 37 112.1 0.94 8.0e-24 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARL3 CD79B CDC42SE2 CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN LOXL1-AS1 LUZP1 MAP1LC3A MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Trunk fat percentage 3.83 20 14 42.4 -0.36 8.9e-02 ADCY3 C7orf36 CENPO DNAJC27 EDEM3 FZD2 GGT7 KIF1B LOC100129961 NOB1 NPC2 PKD1 RAD9A RP11-214K3.24 RP11-259G18.1 RP11-443B20.1 TSC2 YPEL3 Y_RNA ZBTB38
Hand grip strength (right) 14.36 88 73 221.2 0.99 1.7e-96 AC034220.3 ACBD4 ACTR1A ADAM11 ADAMTSL4 ADCY3 AOC1 AQP11 ARFGEF2 ARL3 BANK1 BCS1L BTRC C2CD3 C7orf36 C7orf58 CCS CD79B CDC42SE2 CENPO CHMP1A CKAP4 CRIPAK CYP17A1-AS1 DCAF16 DLEU7 DNAJC27 DYM EDEM3 ELK4 ERP27 FZD2 GGT7 GLDN GOLGA1 HMG20A HOXB2 JAG1 JMJD4 KIF1B LOC100129961 LOXL1-AS1 LRPPRC LUZP1 MAP1LC3A MGP MLST8 MYLK4 NCAPG NCOA1 NOB1 NPC2 NUCKS1 P4HA2 PDLIM4 PILRA PKD1 PML POLD3 PPME1 PSMB3 RAD9A RAPGEF6 RFT1 RP11-214K3.24 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 TFB1M TGFA TMEM106C TMEM180 TNNT3 TOMM22 TP53I3 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF260 ZNF573
Current tobacco smoking 1.64 3 2 6.1 0.00 1.0e+00 ARL3 CYP17A1-AS1 Y_RNA
Maternal smoking around birth 1.81 3 1 3.0 0.00 1.0e+00 ARL3 CYP17A1-AS1 TMEM180
Fed-up feelings 1.45 3 2 6.1 0.00 1.0e+00 EDEM3 RP11-259G18.1 YLPM1
Relative age voice broke 1.58 2 1 3.0 0.00 1.0e+00 RP11-259G18.1 UQCC1
Taking other prescription medications 1.53 1 0 0.0 0.00 1.0e+00 YLPM1
Age when periods started (menarche) 2.11 8 4 12.1 0.51 1.3e-01 AC002550.5 ADCY3 CENPO DNAJC27 NOB1 RP11-443B20.1 YPEL3 Y_RNA
Heel bone mineral density (BMD) T-score, automated (left) 2.80 5 3 9.1 0.23 7.1e-01 C7orf58 CRIPAK FZD2 GLDN JAG1
High blood pressure 1.70 8 3 9.1 -0.77 2.5e-02 AC034220.3 DCAF16 EDEM3 P4HA2 PDLIM4 SLC22A4 TNNT3 ZNF500
Hayfever, allergic rhinitis or eczema 2.29 8 6 18.2 -0.72 4.5e-02 ACTR1A ARL3 CYP17A1-AS1 P4HA2 SLC22A4 SUFU TMEM180 ZBTB38
Multivitamins +/- minerals 1.68 1 0 0.0 0.00 1.0e+00 NUCKS1
Supplements: Glucosamine 1.65 1 0 0.0 0.00 1.0e+00 MGP
Diverticular disease/diverticulitis (self-reported) 1.51 1 0 0.0 0.00 1.0e+00 FZD2
Sitting height 12.33 65 56 169.7 0.90 3.0e-27 AC034220.3 ACBD4 ACTR1A ADAM11 ADCY3 AOC1 ARFGEF2 ARL3 BCS1L C2CD3 CD79B CDC42SE2 CENPO CHMP1A CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DNAJC27 DYM ERP27 FZD2 GGT7 GLDN JAG1 JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NOB1 NUCKS1 P4HA2 PDLIM4 PKD1 PML POLD3 PPME1 PSMB3 RAD9A RAPGEF6 RFT1 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TFB1M TMEM180 TNNT3 TP53I3 TSC2 UQCC1 Y_RNA ZBTB38 ZCCHC24 ZNF260
High blood pressure (mother) 1.76 1 0 0.0 0.00 1.0e+00 TMEM106C
Body mass index (BMI) 4.16 18 12 36.4 -0.70 4.7e-04 AC002550.5 ADCY3 ARFGEF2 ARL3 BANK1 CCS CENPO DNAJC27 EDEM3 LOC100129961 LOXL1-AS1 NOB1 PML RFT1 RP11-214K3.24 RP11-443B20.1 YPEL3 Y_RNA
Impedance of leg (left) 3.17 27 17 51.5 -0.19 2.9e-01 AC002550.5 ACBD4 ADAM11 ADCY3 AOC1 BCS1L CCS CD79B CDC42SE2 CHMP1A DLEU7 DNAJC27 GGT7 HOXB2 LOXL1-AS1 NOB1 NUCKS1 RAD9A RAPGEF6 RFT1 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 TMEM106C UQCC1 YPEL3
Leg predicted mass (left) 7.10 45 37 112.1 0.93 1.2e-22 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARL3 CD79B CDC42SE2 CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Trunk fat mass 3.94 23 21 63.6 0.13 5.2e-01 ADCY3 ARL3 CENPO DNAJC27 EDEM3 FZD2 GGT7 LOC100129961 MLST8 NOB1 NPC2 PKD1 RAD9A RP11-214K3.24 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38
Waist circumference 3.34 15 12 36.4 -0.03 9.0e-01 ADCY3 ARL3 CENPO CRIPAK DNAJC27 EDEM3 GGT7 MLST8 NOB1 PKD1 RAD9A RP11-443B20.1 YPEL3 Y_RNA ZBTB38
Number of incorrect matches in round 2.05 2 1 3.0 0.00 1.0e+00 LOC100129961 YPEL3
Past tobacco smoking 2.80 7 4 12.1 -0.53 1.4e-01 ACTR1A ARL3 CYP17A1-AS1 MAP1LC3A NOB1 SUFU TMEM180
Nervous feelings 1.75 5 2 6.1 -0.67 2.1e-01 ARL3 CYP17A1-AS1 RP11-259G18.1 YLPM1 YPEL3
Frequency of tenseness / restlessness in last 2 weeks 1.46 1 1 3.0 0.00 1.0e+00 RP11-259G18.1
Hearing difficulty/problems with background noise 1.61 2 1 3.0 0.00 1.0e+00 ACTR1A NUCKS1
Hair/balding pattern: Pattern 2 1.61 1 1 3.0 0.00 1.0e+00 RP11-259G18.1
Had menopause 1.18 1 0 0.0 0.00 1.0e+00 RP11-73O6.3
Forced vital capacity (FVC) 7.21 43 29 87.9 0.94 3.2e-24 ACTR1A ADAM11 ADCY3 AOC1 AQP11 ARFGEF2 BCS1L CCS CD79B CENPO CHMP1A CYP17A1-AS1 DCAF16 DIRC3 DNAJC27 DYM FZD2 GGT7 JAG1 JMJD4 LOC100129961 LOXL1-AS1 NCAPG NCOA1 NOB1 PML PSMB3 RAD9A RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 TMEM180 TP53I3 UQCC1 Y_RNA ZBTB38 ZCCHC24 ZNF500 ZNF573
Heel bone mineral density (BMD) T-score, automated (right) 2.73 6 2 6.1 -0.30 5.6e-01 C7orf58 CRIPAK DCAF16 FZD2 GLDN ZBTB38
Ever unenthusiastic/disinterested for a whole week 1.31 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Qualifications: None of the above 1.43 2 1 3.0 0.00 1.0e+00 RFT1 RP11-474G23.2
Mouth/teeth dental problems 1.49 1 0 0.0 0.00 1.0e+00 ELK4
Heart attack 1.66 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Allergy 2.55 10 7 21.2 0.82 3.8e-03 AC034220.3 ACTR1A CYP17A1-AS1 KIF1B P4HA2 PDLIM4 SLC22A4 SUFU TMEM180 ZBTB38
Fluid intelligence score 1.67 3 1 3.0 0.00 1.0e+00 DCAF16 NCAPG Y_RNA
Neuroticism score 2.04 4 3 9.1 0.02 9.8e-01 RP11-259G18.1 TCF4 YLPM1 Y_RNA
Weight 5.32 38 28 84.8 0.73 1.7e-08 AC002550.5 AC034220.3 ACTR1A ADCY3 ARL3 CD79B CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DNAJC27 FZD2 GGT7 GLDN LUZP1 MAP1LC3A MLST8 NCAPG NOB1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TSC2 UQCC1 YPEL3 ZBTB38 ZCCHC24
Impedance of arm (right) 2.38 18 12 36.4 -0.55 1.4e-02 AC002550.5 AOC1 ARL3 CD79B CYP17A1-AS1 DLEU7 KIF1B LOXL1-AS1 MLST8 NUCKS1 RFT1 RP11-214K3.24 RP11-259G18.1 RP11-474G23.2 RP11-73O6.3 RP3-477O4.16 TMEM106C YPEL3
Arm fat percentage (right) 5.10 17 13 39.4 -0.80 1.9e-05 ADCY3 ARFGEF2 BANK1 C7orf36 CCS CD79B CENPO DCAF16 DNAJC27 EDEM3 FZD2 LOC100129961 NOB1 RP11-214K3.24 RP11-443B20.1 YPEL3 Y_RNA
Trunk fat-free mass 9.80 56 48 145.5 0.92 9.6e-26 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 ADCY3 AOC1 ARFGEF2 ARL3 BCS1L BTRC CD79B CDC42SE2 CENPO CHMP1A CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM ERP27 GGT7 GLDN JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PML PSMB3 RAD9A RAPGEF6 RP11-214K3.24 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24
Hip circumference 4.18 23 18 54.5 0.23 2.5e-01 ADCY3 ARL3 BANK1 CD79B CENPO DCAF16 DNAJC27 GGT7 GLDN LOC100129961 LUZP1 MLST8 NOB1 PKD1 RAD9A RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 UQCC1 YPEL3 Y_RNA ZBTB38
Time employed in main current job 1.10 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Father's age at death 1.22 1 0 0.0 0.00 1.0e+00 P4HA2
Worrier / anxious feelings 2.59 8 6 18.2 -0.68 3.0e-02 ACTR1A ARL3 CYP17A1-AS1 RP11-259G18.1 SUFU TCF4 TMEM180 YLPM1
Frequency of tiredness / lethargy in last 2 weeks 2.17 1 0 0.0 0.00 1.0e+00 POLD3
Hair/balding pattern: Pattern 3 1.91 2 1 3.0 0.00 1.0e+00 MAP1LC3A RP11-259G18.1
Number of live births 0.90 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Forced expiratory volume in 1-second (FEV1) 5.97 34 22 66.7 0.95 8.1e-21 ADCY3 AOC1 AQP11 ARFGEF2 BCS1L CCS CD79B CENPO CHMP1A DCAF16 DNAJC27 FZD2 GGT7 GOLGA1 JAG1 LOC100129961 LOXL1-AS1 NCAPG NOB1 P4HA2 RAD9A RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 TP53I3 UQCC1 Y_RNA ZBTB38 ZCCHC24 ZNF500
Pulse rate 1.50 2 1 3.0 0.00 1.0e+00 DLEU7 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.62 4 0 0.0 0.95 1.3e-02 ARFGEF2 DCAF16 NCAPG UQCC1
Mouth/teeth dental problems: Dentures 1.71 2 0 0.0 0.00 1.0e+00 ADCY3 PSMB3
Asthma 2.68 6 4 12.1 -0.98 1.1e-04 AC034220.3 CCS KIF1B P4HA2 PDLIM4 SLC22A4
Medication: Ibuprofen (e.g. Nurofen) 1.76 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Medication: Cholesterol lowering 1.09 1 0 0.0 0.00 1.0e+00 TMEM106C
Forced expiratory volume in 1-second (FEV1), Best measure 5.62 28 18 54.5 0.96 4.6e-18 ADAM11 ADCY3 AOC1 ARFGEF2 BCS1L CCS CD79B DCAF16 DNAJC27 FZD2 JAG1 LOC100129961 LOXL1-AS1 NCAPG NOB1 PDLIM4 RAD9A RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP13-39P12.3 SLC22A4 UQCC1 Y_RNA ZBTB38 ZCCHC24 ZNF500
Pulse wave Arterial Stiffness index 1.90 1 0 0.0 0.00 1.0e+00 RP1-257A7.5
Impedance of arm (left) 2.48 20 11 33.3 -0.49 2.4e-02 AC002550.5 ACBD4 AOC1 ARL3 CD79B CYP17A1-AS1 DLEU7 KIF1B LOXL1-AS1 MLST8 NUCKS1 RAD9A RFT1 RP11-214K3.24 RP11-259G18.1 RP11-73O6.3 RP3-477O4.16 TMEM106C TNNT3 YPEL3
Arm fat mass (right) 3.86 20 11 33.3 -0.26 2.4e-01 AC002550.5 ADCY3 ARL3 CCS CENPO DNAJC27 EDEM3 FZD2 GGT7 LOC100129961 MLST8 NOB1 PKD1 RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 UQCC1 YPEL3 Y_RNA ZBTB38
Trunk predicted mass 9.77 55 49 148.5 0.92 1.3e-25 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 ADCY3 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CENPO CHMP1A CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM ERP27 GGT7 GLDN JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PML PSMB3 RAD9A RAPGEF6 RP11-214K3.24 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24
Standing height 13.04 71 65 197.0 0.89 1.8e-28 AC034220.3 ACBD4 ACTR1A ADAM11 ADCY3 AOC1 AQP11 ARFGEF2 ARL3 BCS1L BTRC C7orf58 CCS CD79B CDC42SE2 CENPO CHMP1A CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DNAJC27 DYM EDEM3 ELK4 FZD2 GGT7 GLDN JAG1 JMJD4 KIF1B LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NOB1 NPC2 NUCKS1 P4HA2 PDLIM4 PKD1 PML PSMB3 RAD9A RAPGEF6 RFT1 RP11-214K3.24 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TFB1M TMEM180 TP53I3 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF260 ZNF500
Tense / 'highly strung' 1.34 2 0 0.0 0.00 1.0e+00 NUCKS1 YPEL3
Seen doctor (GP) for nerves, anxiety, tension or depression 1.64 2 2 6.1 0.00 1.0e+00 CCS TCF4
Hair/balding pattern: Pattern 4 2.36 5 2 6.1 0.29 6.3e-01 GGT7 MAP1LC3A RP11-259G18.1 RP13-39P12.3 ZBTB38
Birth weight of first child 2.09 3 1 3.0 0.00 1.0e+00 ARFGEF2 DCAF16 ZBTB38
Peak expiratory flow (PEF) 5.37 22 10 30.3 0.98 1.7e-18 ACTR1A AQP11 CCS CD79B CHMP1A DCAF16 GGT7 LOXL1-AS1 MAP1LC3A NCAPG NUCKS1 PML RAD9A RP11-259G18.1 RP11-73O6.3 RP3-477O4.16 TMEM106C TMEM180 TP53I3 UQCC1 Y_RNA ZNF573
Qualifications: O levels/GCSEs or equivalent 1.29 1 1 3.0 0.00 1.0e+00 ELK4
Medication: Paracetamol 1.67 2 2 6.1 0.00 1.0e+00 RP11-259G18.1 RP1-257A7.5
Headache pain in last month 2.05 3 3 9.1 0.00 1.0e+00 ADAMTSL4 RP11-259G18.1 RP1-257A7.5
Medication for cholesterol, blood pressure or diabetes 1.19 1 0 0.0 0.00 1.0e+00 TMEM106C
Medication: Amlodipine 1.36 1 0 0.0 0.00 1.0e+00 TNNT3
Birth weight 2.45 5 1 3.0 0.44 4.6e-01 DCAF16 LUZP1 RFT1 RP11-73O6.3 Y_RNA
Forced vital capacity (FVC), Best measure 6.94 39 28 84.8 0.95 7.2e-23 ACTR1A ADAM11 ADCY3 AOC1 ARFGEF2 BCS1L CCS CD79B CENPO CHMP1A DCAF16 DNAJC27 DYM FZD2 GGT7 JAG1 LOC100129961 LOXL1-AS1 LUZP1 NCAPG NCOA1 NOB1 PML PSMB3 RAD9A RFT1 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 TP53I3 UQCC1 Y_RNA ZBTB38 ZCCHC24 ZNF500
Body fat percentage 4.28 20 10 30.3 -0.61 2.3e-03 ADCY3 ARFGEF2 C7orf36 CD79B CENPO DCAF16 DNAJC27 EDEM3 FZD2 LOC100129961 NOB1 NPC2 PKD1 RP11-214K3.24 RP11-259G18.1 RP11-443B20.1 TSC2 YPEL3 Y_RNA ZBTB38
Leg fat percentage (right) 4.65 16 13 39.4 -0.81 2.8e-05 ADCY3 ARFGEF2 ARL3 CD79B CENPO DCAF16 DNAJC27 EDEM3 LOC100129961 NCAPG NOB1 RP11-214K3.24 RP11-443B20.1 UQCC1 YPEL3 Y_RNA
Arm fat-free mass (right) 8.24 50 43 130.3 0.93 7.7e-26 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L C2CD3 CD79B CDC42SE2 CHMP1A CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM GGT7 HMG20A LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 TSC2 UQCC1 YPEL3 ZBTB38 ZCCHC24
Comparative body size at age 10 10.60 10 8 24.2 -0.60 3.9e-02 AC002550.5 ADCY3 CENPO DNAJC27 NCOA1 NUCKS1 PILRA RP11-443B20.1 YPEL3 Y_RNA
Number of full brothers 1.09 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Worry too long after embarrassment 1.39 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Wheeze or whistling in the chest in last year 1.57 3 0 0.0 0.00 1.0e+00 GOLGA1 NCAPG YPEL3
Age at first live birth 1.16 2 0 0.0 0.00 1.0e+00 DCAF16 EDEM3
Qualifications: College or University degree 1.61 9 2 6.1 0.48 1.6e-01 ARFGEF2 ARL3 BTRC CYP2D6 DCAF16 EDEM3 PILRA RP11-259G18.1 UQCC1
Medication for pain relief, constipation, heartburn 1.99 3 1 3.0 0.00 1.0e+00 FZD2 RP11-259G18.1 RP1-257A7.5
Neck or shoulder pain in last month 1.52 1 0 0.0 0.00 1.0e+00 YPEL3
Medication: Blood pressure 1.49 1 0 0.0 0.00 1.0e+00 DCAF16
Angina (self-reported) 1.95 2 1 3.0 0.00 1.0e+00 GGT7 RP1-257A7.5
Migraine (self-reported) 2.15 2 1 3.0 0.00 1.0e+00 ADAMTSL4 RP1-257A7.5
Medication: Ibuprofen 1.36 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Medication: Seretide 50 evohaler 1.57 3 0 0.0 0.00 1.0e+00 P4HA2 PDLIM4 SLC22A4
Mean time to correctly identify matches 1.75 5 1 3.0 0.32 6.0e-01 ADCY3 ARFGEF2 CENPO NUCKS1 RP11-73O6.3
Heart disease (mother) 1.39 1 0 0.0 0.00 1.0e+00 RP1-257A7.5
Whole body fat mass 3.81 22 18 54.5 0.01 9.7e-01 ADCY3 ARL3 CENPO DNAJC27 EDEM3 FZD2 GGT7 LOC100129961 MLST8 NOB1 NPC2 PKD1 RAD9A RP11-214K3.24 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38
Leg fat mass (right) 3.66 19 13 39.4 -0.25 2.7e-01 ADCY3 ARL3 CENPO CYP17A1-AS1 DNAJC27 EDEM3 GGT7 LOC100129961 MLST8 NOB1 PKD1 RAD9A RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 TSC2 YPEL3 Y_RNA ZBTB38
Arm predicted mass (right) 8.16 49 44 133.3 0.93 1.7e-25 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L C2CD3 CD79B CDC42SE2 CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM GGT7 HMG20A LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 TSC2 UQCC1 YPEL3 ZBTB38 ZCCHC24
Pulse rate, automated reading 1.36 4 1 3.0 -0.25 7.5e-01 C2CD3 CRIPAK LOC100129961 ZBTB38
Alcohol intake frequency. 1.59 6 4 12.1 -0.67 1.4e-01 PILRA RP11-259G18.1 RP1-257A7.5 TCF4 YPEL3 Y_RNA
Comparative height size at age 10 10.49 57 52 157.6 0.90 4.4e-24 AC034220.3 ACTR1A ADAM11 ADCY3 AOC1 ARFGEF2 ARL3 BCS1L BTRC CCS CD79B CENPO CHMP1A CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DNAJC27 DYM FZD2 GGT7 JMJD4 KIF1B LOXL1-AS1 MAP1LC3A MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PML PSMB3 RAD9A RAPGEF6 RFT1 RP11-250B2.6 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TCF4 TFB1M TMEM180 TP53I3 TSC2 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF260
Suffer from 'nerves' 1.53 2 1 3.0 0.00 1.0e+00 YLPM1 Y_RNA
Overall health rating 1.89 3 1 3.0 -0.99 5.3e-03 CCS GOLGA1 TMEM106C
Knee pain experienced in last month 2.38 3 2 6.1 -1.00 3.1e-03 RP3-477O4.16 TMEM106C UQCC1
Hypertension (Self-reported) 1.75 9 3 9.1 -0.79 1.2e-02 AC034220.3 DCAF16 EDEM3 P4HA2 PDLIM4 SLC22A4 TNNT3 TSC2 ZNF500
Illnesses of father: Heart disease 1.83 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Forced expiratory volume in 1-second (FEV1), predicted 7.60 27 16 48.5 0.96 4.6e-18 AC034220.3 ACTR1A ADCY3 BCS1L CD79B CYP17A1-AS1 DCAF16 DNAJC27 DYM GGT7 LOXL1-AS1 MAP1LC3A MLST8 NCAPG P4HA2 PDLIM4 RAD9A RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 SLC22A4 TMEM180 TP53I3 UQCC1 Y_RNA ZBTB38 ZCCHC24
Whole body fat-free mass 8.78 49 45 136.4 0.93 9.1e-25 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg fat-free mass (right) 7.31 48 39 118.2 0.93 1.5e-23 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TFB1M TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Arm fat percentage (left) 5.12 16 13 39.4 -0.81 2.9e-05 ADCY3 ARFGEF2 C7orf36 CCS CD79B CENPO DCAF16 DNAJC27 EDEM3 FZD2 LOC100129961 NOB1 RP11-214K3.24 RP11-443B20.1 YPEL3 Y_RNA
Handedness (chirality/laterality): Left-handed 1.20 1 1 3.0 0.00 1.0e+00 RP11-259G18.1
Mood swings 1.83 4 3 9.1 -0.36 6.4e-01 NUCKS1 RP11-259G18.1 TCF4 YLPM1
Loneliness, isolation 1.73 3 0 0.0 0.00 1.0e+00 ARFGEF2 RP11-259G18.1 Y_RNA
Long-standing illness, disability or infirmity 1.69 1 0 0.0 0.00 1.0e+00 NOB1
Diabetes diagnosed by doctor 1.74 1 0 0.0 0.00 1.0e+00 NOB1
Mouth/teeth dental problems: Mouth ulcers 1.35 1 1 3.0 0.00 1.0e+00 RP11-259G18.1
Medication for cholesterol 1.41 1 0 0.0 0.00 1.0e+00 ZNF500
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.27 1 0 0.0 0.00 1.0e+00 ADAMTSL4
Asthma (self-reported) 2.64 6 4 12.1 -0.98 1.0e-04 AC034220.3 CCS KIF1B P4HA2 PDLIM4 SLC22A4
Osteoarthritis (self-reported) 2.06 1 1 3.0 0.00 1.0e+00 TGFA
Smoking status: Current 1.70 4 2 6.1 0.98 2.4e-02 ARL3 CYP17A1-AS1 TMEM180 Y_RNA
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.92 5 3 9.1 0.12 8.3e-01 JAG1 NOB1 RP11-259G18.1 UQCC1 YPEL3
Whole body water mass 8.70 49 45 136.4 0.93 4.7e-24 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM ERP27 GGT7 GLDN JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg predicted mass (right) 7.32 47 39 118.2 0.93 3.6e-23 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CRIPAK CYP17A1-AS1 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Arm fat mass (left) 3.90 21 13 39.4 -0.17 4.3e-01 AC002550.5 ADCY3 ARL3 CCS CENPO DNAJC27 EDEM3 FZD2 GGT7 LOC100129961 MLST8 NOB1 PKD1 RAD9A RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 UQCC1 YPEL3 Y_RNA ZBTB38
Number of self-reported non-cancer illnesses 1.98 3 0 0.0 0.11 8.9e-01 CCS NCAPG SLC22A4
Average weekly champagne plus white wine intake 1.07 1 0 0.0 0.00 1.0e+00 RP11-259G18.1
Miserableness 1.87 4 2 6.1 0.54 4.6e-01 LOXL1-AS1 RP11-259G18.1 TCF4 Y_RNA
Guilty feelings 1.63 2 1 3.0 0.00 1.0e+00 RP11-259G18.1 YLPM1
Medication: Blood pressure 1.75 5 2 6.1 0.34 5.8e-01 CHMP1A P4HA2 RP11-259G18.1 TNNT3 ZNF500
High cholesterol (Self-reported) 1.07 2 0 0.0 0.00 1.0e+00 DCAF16 TMEM106C
Medication: Bendroflumethiazide 1.64 3 0 0.0 0.00 1.0e+00 AC034220.3 P4HA2 PDLIM4
Medication: Paracetamol 1.75 2 1 3.0 0.00 1.0e+00 RP11-259G18.1 RP1-257A7.5
Alcohol drinker status: Never 1.10 1 0 0.0 0.00 1.0e+00 Y_RNA
Ever smoked 2.03 4 1 3.0 1.00 3.5e-04 ACTR1A ARL3 CYP17A1-AS1 TMEM180
Basal metabolic rate 7.91 49 41 124.2 0.93 1.6e-24 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM FZD2 GGT7 GLDN JMJD4 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg fat percentage (left) 4.73 17 15 45.5 -0.80 2.3e-05 ADCY3 ARFGEF2 ARL3 CD79B CENPO DCAF16 DNAJC27 EDEM3 LOC100129961 NCAPG NOB1 PML RP11-214K3.24 RP11-443B20.1 UQCC1 YPEL3 Y_RNA
Arm fat-free mass (left) 7.97 49 42 127.3 0.93 2.6e-25 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L C2CD3 CD79B CDC42SE2 CHMP1A CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM GGT7 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TP53I3 TSC2 UQCC1 YPEL3 ZBTB38 ZCCHC24
Irritability 1.53 2 1 3.0 0.00 1.0e+00 RP11-259G18.1 TCF4
Ever had prostate specific antigen (PSA) test 1.36 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 2.20 2 1 3.0 0.00 1.0e+00 C7orf58 MGP
Diastolic blood pressure, automated reading 1.61 6 3 9.1 -0.19 7.1e-01 ADCY3 BANK1 DCAF16 JAG1 LOC100129961 P4HA2
Commuting to job workplace: Cycle 1.51 1 0 0.0 0.00 1.0e+00 NCAPG
Vascular/heart problems diagnosed by doctor 1.67 9 4 12.1 0.82 6.2e-03 AC034220.3 DCAF16 EDEM3 NCAPG P4HA2 PDLIM4 SLC22A4 TNNT3 ZNF500
Cholesterol lowering medication 1.33 1 0 0.0 0.00 1.0e+00 DCAF16
Heart attack/myocardial infarction (self-reported) 1.61 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Heart disease (siblings) 1.54 1 1 3.0 0.00 1.0e+00 RP1-257A7.5
Impedance of whole body 2.81 28 18 54.5 -0.31 7.2e-02 AC002550.5 ACBD4 ADCY3 AOC1 ARL3 CCS CD79B CYP17A1-AS1 DLEU7 DNAJC27 GGT7 HOXB2 KIF1B LOXL1-AS1 LUZP1 NUCKS1 RAD9A RAPGEF6 RFT1 RP11-214K3.24 RP11-259G18.1 RP11-443B20.1 RP11-73O6.3 RP3-477O4.16 TMEM106C TNNT3 UQCC1 YPEL3
Leg fat mass (left) 3.71 19 15 45.5 -0.25 2.7e-01 ADCY3 ARL3 CENPO CYP17A1-AS1 DNAJC27 EDEM3 GGT7 LOC100129961 MLST8 NOB1 PKD1 RAD9A RP11-214K3.24 RP11-443B20.1 RP11-73O6.3 TSC2 YPEL3 Y_RNA ZBTB38
Arm predicted mass (left) 8.02 49 41 124.2 0.93 1.7e-25 AC002550.5 AC034220.3 ACBD4 ACTR1A ADAM11 AOC1 ARFGEF2 ARL3 BCS1L CD79B CDC42SE2 CHMP1A CRIPAK CYP17A1-AS1 CYP2D6 DCAF16 DIRC3 DLEU7 DYM GGT7 LOXL1-AS1 LUZP1 MAP1LC3A MGP MLST8 NCAPG NCOA1 NUCKS1 P4HA2 PDLIM4 PKD1 PSMB3 RAD9A RAPGEF6 RP11-250B2.6 RP11-474G23.2 RP11-73O6.3 RP13-39P12.3 RP3-477O4.16 SLC22A4 SUFU TMEM180 TNNT3 TP53I3 TSC2 UQCC1 YPEL3 ZBTB38 ZCCHC24

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 42 1.203 2.78
GTEx Adipose Visceral Omentum 18 0.884 2.75
GTEx Adrenal Gland 18 1.235 2.66
GTEx Artery Aorta 35 1.176 2.82
GTEx Artery Coronary 16 1.352 2.91
GTEx Artery Tibial 32 0.851 2.68
GTEx Brain Caudate basal ganglia 12 1.304 2.75
GTEx Brain Cerebellar Hemisphere 19 1.276 2.85
GTEx Brain Cerebellum 22 1.110 2.75
GTEx Brain Cortex 22 2.126 3.02
GTEx Brain Frontal Cortex BA9 16 1.732 2.87
GTEx Brain Hippocampus 8 1.527 3.01
GTEx Brain Hypothalamus 9 1.525 2.88
GTEx Brain Nucleus accumbens basal ganglia 17 1.965 3.09
GTEx Brain Putamen basal ganglia 9 1.442 2.86
GTEx Breast Mammary Tissue 26 1.317 2.75
GTEx Breast Mammary Tissue (Male) 19 1.593 2.86
GTEx Breast Mammary Tissue (Female) 20 1.217 2.62
GTEx Cells EBV-transformed lymphocytes 24 1.687 2.99
GTEx Cells Transformed fibroblasts 39 0.929 2.65
GTEx Colon Sigmoid 15 1.026 2.64
GTEx Colon Transverse 26 1.260 2.73
GTEx Esophagus Gastroesophageal Junction 19 1.315 2.76
GTEx Esophagus Mucosa 37 1.114 2.78
GTEx Esophagus Muscularis 31 0.959 2.62
GTEx Heart Atrial Appendage 18 1.140 2.84
GTEx Heart Left Ventricle 18 1.176 2.62
GTEx Liver 11 1.534 3.01
GTEx Lung 34 1.183 2.80
GTEx Muscle Skeletal 37 1.280 2.83
GTEx Nerve Tibial 48 1.111 2.71
GTEx Ovary 17 1.872 3.03
GTEx Pancreas 18 1.103 2.67
GTEx Pituitary 16 1.435 3.08
GTEx Prostate 15 1.796 2.86
GTEx Skin Not Sun Exposed Suprapubic 28 1.139 2.81
GTEx Skin Sun Exposed Lower leg 41 1.126 2.80
GTEx Small Intestine Terminal Ileum 9 1.952 2.90
GTEx Spleen 20 1.417 2.97
GTEx Stomach 23 1.582 2.77
GTEx Testis 39 1.236 2.81
GTEx Thyroid 43 1.075 2.66
GTEx Uterus 13 2.293 3.21
GTEx Vagina 10 1.575 2.89
GTEx Whole Blood 27 1.355 2.83
METSIM Adipose 33 0.716 2.44
NTR Blood 21 0.874 2.52
ROSMAP Brain Pre-frontal Cortex 37 0.843 2.55
YFS Blood 31 0.671 2.43
CommonMind Brain Pre-frontal Cortex 33 0.614 2.44
TCGA Breast Tumor 6 0.782 2.44
TCGA Breast Normal 26 0.618 2.40
TCGA Ovarian Tumor 18 0.616 2.25
TCGA Prostate Tumor 20 0.578 2.51