Hub : Traits :

Hand grip strength (right)

1152 significantly associated models · 260 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 9576675 11137778 1 1 1.1e-11 8.1e-10 6.3e-03 80 KIF1B
2 1 40791792 42187205 1 1 1.8e-09 5.8e-11 6.6e-03 83 SLFNL1
3 1 149815323 151227371 3 1 4.3e-08 5.9e-08 1.0e+00 100 ADAMTSL4
4 1 159559531 161006019 1 1 6.2e-09 4.3e-08 3.5e-01 97 COPA
5 1 183325796 184739300 1 1 3.3e-07 2.0e-07 1.0e+00 100 TSEN15
6 1 204888754 206329620 6 1 8.2e-17 1.4e-16 1.0e+00 100 NUCKS1
7 1 227217340 228663659 2 1 9.9e-10 7.8e-11 1.7e-02 86 SNAP47
8 2 23604114 25889403 7 5 2.3e-14 8.0e-16 NaN NaN ADCY3 NCOA1 TP53I3
9 2 43342098 44920960 2 1 1.0e-08 5.6e-09 3.7e-02 87 LRPPRC
10 2 47979687 49429109 2 1 1.6e-08 3.6e-09 1.0e+00 100 PPP1R21
11 2 67709195 69180661 2 1 4.2e-08 3.6e-08 3.2e-01 97 PPP3R1
12 2 69978290 71471456 1 2 3.0e-17 3.5e-17 4.7e-03 89 TGFA
13 2 134513621 136403272 4 1 2.9e-12 1.6e-11 5.4e-01 99 LOC100129961
14 2 171683107 173114238 1 1 1.8e-07 3.0e-07 8.8e-02 89 CYBRD1
15 2 178748168 180139951 1 1 2.2e-07 2.3e-06 9.8e-01 100 RP11-171I2.2
16 2 197976089 199706580 1 1 9.3e-08 3.3e-07 8.2e-03 73 PLCL1
17 3 52020411 53860103 6 2 1.4e-10 2.3e-09 3.9e-01 98 GNL3 RFT1
18 3 140350567 141867638 1 1 6.7e-08 4.0e-09 1.0e+00 100 ZBTB38
19 4 305291 2058475 4 1 8.0e-10 4.9e-08 3.4e-03 71 CRIPAK
20 4 17104059 18533844 2 1 4.7e-19 3.6e-19 2.0e-03 88 DCAF16
21 4 143781835 145154483 1 1 2.1e-08 4.3e-06 9.3e-01 100 LOC441046
22 5 129797129 132852187 15 7 5.4e-17 2.4e-16 1.0e+00 100 CDC42SE2 P4HA2-AS1 PDLIM4 RAPGEF6 SLC22A4 SLC22A5
23 6 1967240 3450266 1 1 2.9e-08 8.7e-07 7.2e-01 100 MYLK4
24 6 14551209 16209635 1 1 6.8e-08 1.3e-09 5.6e-03 79 JARID2
25 6 33856903 35362848 1 1 2.6e-08 6.6e-07 5.9e-04 52 C6orf106
26 6 80120201 81763771 2 2 2.0e-09 2.2e-06 8.6e-01 100 BCKDHB RP11-250B2.6
27 6 129638583 131163098 2 1 2.7e-20 9.4e-18 8.5e-01 100 L3MBTL3
28 6 154891396 156330580 1 1 1.3e-07 4.6e-10 8.2e-05 60 TFB1M
29 7 99275083 101185166 5 4 3.0e-09 6.2e-08 4.5e-01 98 GIGYF1 PILRA SRRT TFR2
30 7 119935156 121630503 1 1 1.8e-09 3.7e-08 8.5e-03 77 C7orf58
31 9 98515578 100049972 2 1 1.2e-07 2.7e-08 1.0e+00 100 HABP4
32 9 126844856 128680148 7 1 4.1e-09 1.7e-08 4.4e-01 98 SCAI
33 9 136197834 137631198 1 1 9.2e-08 1.6e-07 1.0e+00 100 BRD3
34 10 78845149 80383574 2 1 4.8e-08 5.2e-08 2.4e-01 95 DLG5
35 10 80443273 82307117 6 2 2.5e-11 2.3e-10 1.8e-01 96 BEND3P3 ZCCHC24
36 10 102416555 105694301 9 11 2.1e-11 2.7e-10 NaN NaN ACTR1A ARL3 BTRC CYP17A1-AS1 RP11-332O19.5 SFXN2 SUFU TMEM180
37 10 120164251 121596611 1 1 2.3e-07 1.1e-08 8.0e-04 66 FAM45A
38 10 133309117 134717136 1 1 3.6e-07 8.4e-08 8.4e-02 90 DPYSL4
39 11 46622392 48485877 5 1 9.2e-10 6.2e-09 1.9e-03 72 Y_RNA
40 11 66468469 67856510 1 1 1.5e-17 4.3e-17 1.0e+00 100 RAD9A
41 11 73024914 75075866 4 5 8.5e-14 4.7e-22 2.7e-02 95 AP001372.2 C2CD3 POLD3 PPME1
42 11 76537114 78216992 3 1 1.2e-13 2.8e-11 2.0e-02 88 AQP11
43 12 14220891 16190627 8 1 7.6e-25 1.0e-21 3.4e-02 95 ARHGDIB
44 12 47671905 49133725 2 1 9.6e-09 1.3e-06 2.2e-01 94 TMEM106C
45 12 101713020 103148974 1 1 8.0e-08 2.5e-06 8.4e-02 86 CCDC53
46 12 123558705 125270773 6 1 1.9e-09 2.1e-08 3.1e-02 85 DNAH10
47 13 20282946 21962773 2 2 9.2e-08 3.8e-06 1.2e-01 89 CRYL1 IFT88
48 13 49970938 52109040 2 2 9.9e-08 5.7e-19 4.2e-09 56 DLEU1 DLEU7
49 15 50944589 52392509 1 1 1.6e-08 2.9e-10 3.9e-03 79 GLDN
50 15 73524629 76350952 4 4 1.0e-12 2.2e-13 1.5e-08 40 LOXL1-AS1 MAN2C1 PML
51 15 77023336 78474476 1 1 2.1e-11 5.9e-11 1.0e-02 85 HMG20A
52 16 1381714 2838000 3 2 3.1e-14 1.1e-14 8.2e-02 95 SLC9A3R2 TSC2
53 16 24162204 25620010 1 1 6.8e-09 4.2e-09 1.0e+00 100 SLC5A11
54 16 27691641 30803299 7 2 5.2e-08 5.8e-08 6.7e-02 89 NFATC2IP YPEL3
55 16 69062879 71093625 5 1 2.6e-11 9.6e-11 2.2e-03 78 RP11-296I10.3
56 16 88643457 90172696 2 1 8.1e-08 1.0e-09 3.1e-03 76 ANKRD11
57 17 36211659 37644854 2 1 4.9e-17 1.0e-13 1.0e-01 95 PIP4K2B
58 17 41946180 43913030 16 3 2.7e-11 9.0e-12 2.4e-02 89 CRHR1 FZD2 PLCD3
59 17 44788310 47357969 12 2 6.6e-11 8.3e-12 4.6e-03 83 HOXB2 LRRC37A2
60 17 60821100 62694738 12 2 2.3e-13 4.7e-12 1.0e+00 100 CD79B CYB561
61 17 62973790 64251733 1 1 2.0e-08 1.9e-08 4.2e-03 74 AXIN2
62 18 12300136 13822256 1 1 3.3e-08 8.0e-09 7.7e-05 53 CEP192
63 18 45873080 47686517 1 1 3.4e-09 4.2e-12 2.7e-04 72 DYM
64 19 1473344 2923263 1 1 9.1e-09 2.6e-09 6.3e-02 90 DOT1L
65 19 37350856 39002725 4 2 1.9e-08 1.9e-08 1.8e-02 82 ZNF571 ZNF607
66 20 9925555 11347455 1 1 4.0e-07 1.8e-05 1.4e-03 45 JAG1
67 20 32254831 35298668 33 6 1.9e-34 2.8e-38 NaN NaN GGT7 MAP1LC3A RP3-477O4.16 UQCC1
68 20 46838455 48591758 4 1 1.2e-09 1.6e-09 2.7e-01 97 ARFGEF2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 0.96 1 0 0.0 0.00 1.0e+00 YPEL3
Crohns Disease (2017) 3.45 10 7 21.2 0.50 8.1e-02 ADCY3 GIGYF1 NFATC2IP P4HA2-AS1 PDLIM4 RAPGEF6 RFT1 SLC22A4 SLC22A5 ZBTB38
Irritable Bowel Disease (IBD) 2.78 10 5 15.2 0.32 2.8e-01 ADAMTSL4 ADCY3 GIGYF1 NCOA1 NFATC2IP P4HA2-AS1 PDLIM4 RAPGEF6 SLC22A4 SLC22A5
Ulcerative Colitis (UC) 1.58 2 0 0.0 0.00 1.0e+00 NFATC2IP SLC22A5
Reaction Time 1.97 5 1 3.0 0.19 7.6e-01 ADCY3 ARFGEF2 DNAH10 LRRC37A2 TMEM180
Verbal and Numeric Reasoning (VNR) 1.87 7 3 9.1 -0.77 4.2e-02 ARFGEF2 CRHR1 DCAF16 HABP4 NFATC2IP SLC5A11 Y_RNA
Breast Cancer 2.55 12 6 18.2 0.30 2.9e-01 ADCY3 CRHR1 CYBRD1 KIF1B L3MBTL3 LRRC37A2 MAN2C1 P4HA2-AS1 PILRA SLC22A5 TGFA ZBTB38
Ovarian Cancer 1.51 3 2 6.1 0.00 1.0e+00 CRHR1 HOXB2 LRRC37A2
Prostate Cancer 1.90 3 0 0.0 0.00 1.0e+00 NUCKS1 SUFU TMEM180
Bipolar Disorder 1.94 1 0 0.0 0.00 1.0e+00 LOC441046
Body Mass Index (BMI) (2010) 2.32 4 3 9.1 0.73 1.0e-01 ADCY3 GGT7 NFATC2IP Y_RNA
Coronary Artery Disease (CAD) 1.97 1 0 0.0 0.00 1.0e+00 DNAH10
Crohns Disease (2012) 3.09 5 3 9.1 -0.80 5.7e-02 NFATC2IP P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
HDL Cholesterol 1.78 4 2 6.1 0.02 9.8e-01 C6orf106 DNAH10 GNL3 Y_RNA
Neuroticism 1.57 2 1 3.0 0.00 1.0e+00 CRHR1 LRRC37A2
Schizophrenia 1.85 6 3 9.1 0.71 7.1e-02 ACTR1A ARL3 CYP17A1-AS1 GIGYF1 RP11-332O19.5 YPEL3
Triglycerides 1.19 1 0 0.0 0.00 1.0e+00 DNAH10
Ulcerative Colitis 1.73 1 0 0.0 0.00 1.0e+00 SLC22A5
Blood Eosinophil Count 5.22 15 11 33.3 0.68 2.9e-03 ADCY3 BRD3 CRHR1 KIF1B LRRC37A2 P4HA2-AS1 PDLIM4 PLCD3 RAPGEF6 RFT1 RP11-296I10.3 SLC22A4 SLC22A5 YPEL3 ZNF571
Blood Platelet Count 2.34 29 21 63.6 0.54 2.0e-03 AQP11 BRD3 BTRC C6orf106 COPA CRHR1 CYP17A1-AS1 DCAF16 FZD2 HABP4 HMG20A HOXB2 KIF1B MAN2C1 P4HA2-AS1 PDLIM4 PILRA RAPGEF6 RP11-332O19.5 SLC22A4 SLC22A5 SLFNL1 SUFU TFR2 TGFA TMEM106C TMEM180 Y_RNA ZCCHC24
Blood Red Count 2.50 23 18 54.5 0.04 8.6e-01 BRD3 C6orf106 CD79B CRHR1 CYP17A1-AS1 DNAH10 DOT1L GIGYF1 HOXB2 L3MBTL3 LOC100129961 LRRC37A2 MAN2C1 MAP1LC3A NFATC2IP PLCD3 RAD9A SLC9A3R2 TFR2 TMEM106C TP53I3 YPEL3 ZBTB38
Blood White Count 2.73 29 21 63.6 0.43 1.5e-02 ACTR1A ADAMTSL4 ADCY3 CRHR1 CYP17A1-AS1 DCAF16 DLEU1 DLG5 DNAH10 GGT7 HABP4 L3MBTL3 MAN2C1 P4HA2-AS1 PDLIM4 PILRA RAPGEF6 RP11-296I10.3 RP11-332O19.5 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SUFU TMEM180 TP53I3 TSC2 YPEL3 Y_RNA
Heel T-Score 4.31 37 32 97.0 0.06 7.1e-01 ANKRD11 ARHGDIB AXIN2 BCKDHB C7orf58 CEP192 CRHR1 CRIPAK CYBRD1 DCAF16 DLEU1 DNAH10 DOT1L DPYSL4 FZD2 GGT7 GIGYF1 GLDN JAG1 KIF1B L3MBTL3 LRRC37A2 MAP1LC3A PILRA PIP4K2B RFT1 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SRRT TFR2 TMEM106C TSC2 YPEL3 ZBTB38 ZCCHC24
BMI 3.29 24 14 42.4 0.32 9.6e-02 ACTR1A ADCY3 ARFGEF2 ARL3 BRD3 C6orf106 CYBRD1 CYP17A1-AS1 DNAH10 DPYSL4 GGT7 HABP4 L3MBTL3 LOC100129961 LOXL1-AS1 NCOA1 NFATC2IP PML RFT1 RP11-296I10.3 SLC5A11 SLC9A3R2 YPEL3 Y_RNA
Height 12.21 87 80 242.4 -0.86 1.4e-29 ADCY3 AP001372.2 AQP11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BEND3P3 BRD3 BTRC C6orf106 C7orf58 CCDC53 CD79B CDC42SE2 CEP192 CRHR1 CRIPAK CRYL1 CYB561 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A FZD2 GGT7 GIGYF1 GLDN GNL3 HABP4 IFT88 JAG1 KIF1B L3MBTL3 LOC441046 LOXL1-AS1 LRRC37A2 MAN2C1 MAP1LC3A NCOA1 NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PML POLD3 PPME1 PPP3R1 RAD9A RAPGEF6 RFT1 RP11-171I2.2 RP11-250B2.6 RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SRRT SUFU TFB1M TMEM106C TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF571 ZNF607
Waist Hip Ratio (WHR) 3.10 19 14 42.4 0.41 6.9e-02 C6orf106 C7orf58 CCDC53 CD79B CRHR1 CYBRD1 DNAH10 DOT1L GGT7 GNL3 L3MBTL3 LRRC37A2 MAN2C1 PIP4K2B RAD9A RP11-250B2.6 SNAP47 UQCC1 ZBTB38
Systolic Blood Pressure 2.48 24 14 42.4 0.02 9.1e-01 ACTR1A ADCY3 ARFGEF2 ARL3 CRHR1 CYBRD1 CYP17A1-AS1 DCAF16 HOXB2 LOC100129961 LRPPRC LRRC37A2 PLCD3 PPP3R1 RP11-296I10.3 RP3-477O4.16 SFXN2 SLC5A11 SLC9A3R2 SLFNL1 TFR2 TMEM106C UQCC1 Y_RNA
Smoking Status 3.25 11 6 18.2 -0.63 1.5e-02 ACTR1A ARL3 CYP17A1-AS1 LRRC37A2 MAP1LC3A RP11-296I10.3 RP11-332O19.5 SCAI SLC5A11 SUFU TMEM180
Allergy or Eczema 2.10 11 4 12.1 0.40 1.8e-01 C6orf106 CYP17A1-AS1 L3MBTL3 MAP1LC3A NFATC2IP P4HA2-AS1 RP11-332O19.5 SLC22A5 SUFU TMEM180 ZBTB38
Cardiovascular Disease 1.33 9 4 12.1 0.98 1.5e-06 CYP17A1-AS1 DCAF16 JARID2 LRPPRC NFATC2IP PPP3R1 SFXN2 TMEM106C TSC2
Hypothyroidism (self reported) 1.05 2 1 3.0 0.00 1.0e+00 DLEU1 GIGYF1
Respiratory disease 2.16 5 5 15.2 1.00 2.3e-05 KIF1B P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
Type 2 Diabetes (T2D) 1.69 3 0 0.0 0.00 1.0e+00 GIGYF1 MAN2C1 Y_RNA
Lung FEV1/FVC ratio 2.01 17 11 33.3 -0.16 5.0e-01 ACTR1A ADCY3 C6orf106 CRHR1 GGT7 HOXB2 LOXL1-AS1 MAP1LC3A NCOA1 NUCKS1 P4HA2-AS1 PIP4K2B RP11-332O19.5 SLC22A5 UQCC1 YPEL3 ZBTB38
Lung FVC 3.54 33 22 66.7 0.00 1.0e+00 ADAMTSL4 ARFGEF2 BCKDHB CD79B CRHR1 DCAF16 DOT1L FZD2 GGT7 GLDN HOXB2 JAG1 KIF1B LOC100129961 LOXL1-AS1 LRRC37A2 MAN2C1 MAP1LC3A NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PPP1R21 RAD9A RP11-171I2.2 RP11-296I10.3 RP3-477O4.16 SLC22A4 SLC22A5 TFB1M TMEM106C UQCC1 ZBTB38
Neuroticism 2.18 4 2 6.1 0.75 2.5e-01 CRHR1 CYP17A1-AS1 LRRC37A2 Y_RNA
Chronotype (morning person) 1.59 3 1 3.0 0.00 1.0e+00 ADAMTSL4 CRIPAK CYB561
Hair Pigment 0.92 15 13 39.4 0.35 1.5e-01 ADCY3 ANKRD11 CRHR1 GGT7 GIGYF1 KIF1B L3MBTL3 LOC100129961 MAP1LC3A NUCKS1 RP3-477O4.16 SRRT TFR2 UQCC1 ZBTB38
Tanning 1.60 11 6 18.2 -0.58 2.3e-02 ADAMTSL4 ADCY3 ANKRD11 CYBRD1 CYP17A1-AS1 GGT7 MAP1LC3A RP11-332O19.5 RP3-477O4.16 UQCC1 Y_RNA
Hand grip strength (left) 13.69 96 71 215.2 0.99 3.9e-104 ACTR1A ADAMTSL4 ADCY3 AP001372.2 AQP11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BEND3P3 BRD3 BTRC C2CD3 C6orf106 C7orf58 CCDC53 CD79B CDC42SE2 CEP192 COPA CRHR1 CRIPAK CRYL1 CYB561 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FZD2 GGT7 GLDN HABP4 HMG20A HOXB2 IFT88 JAG1 KIF1B L3MBTL3 LOC100129961 LOC441046 LOXL1-AS1 LRPPRC LRRC37A2 MAP1LC3A MYLK4 NCOA1 NUCKS1 P4HA2-AS1 PDLIM4 PILRA PIP4K2B PLCD3 PLCL1 PML POLD3 PPME1 PPP1R21 PPP3R1 RAD9A RAPGEF6 RFT1 RP11-171I2.2 RP11-250B2.6 RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SRRT SUFU TFB1M TFR2 TGFA TMEM106C TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF571 ZNF607
Number of treatments/medications taken 1.58 2 0 0.0 0.00 1.0e+00 DCAF16 NUCKS1
Sensitivity / hurt feelings 1.93 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Frequency of depressed mood in last 2 weeks 1.28 2 0 0.0 0.00 1.0e+00 ARFGEF2 LRRC37A2
Relative age of first facial hair 2.25 5 3 9.1 -0.59 2.9e-01 C6orf106 CRHR1 GGT7 LRRC37A2 ZBTB38
Systolic blood pressure, automated reading 2.12 11 7 21.2 -0.24 4.5e-01 CRHR1 CYP17A1-AS1 DCAF16 DLEU1 LOC100129961 LRRC37A2 PPP3R1 SFXN2 SLC5A11 SLC9A3R2 SLFNL1
Angina 1.25 1 0 0.0 0.00 1.0e+00 GGT7
Medication: Metformin 1.71 1 0 0.0 0.00 1.0e+00 Y_RNA
Pack years adult smoking proportion 1.61 1 0 0.0 0.00 1.0e+00 CYB561
Impedance of leg (right) 2.72 25 18 54.5 -0.45 1.7e-02 ACTR1A ADCY3 ANKRD11 CD79B CDC42SE2 CYBRD1 CYP17A1-AS1 DLEU1 DLEU7 GGT7 HOXB2 L3MBTL3 LOXL1-AS1 NFATC2IP NUCKS1 PLCD3 RAD9A RAPGEF6 RFT1 RP3-477O4.16 SNAP47 TMEM106C TSEN15 UQCC1 YPEL3
Leg fat-free mass (left) 7.54 51 40 121.2 0.91 1.9e-22 ACTR1A ANKRD11 ARL3 AXIN2 C6orf106 CD79B CDC42SE2 CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 L3MBTL3 LOXL1-AS1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Trunk fat percentage 3.22 19 14 42.4 -0.11 6.4e-01 ADCY3 BRD3 C6orf106 CRHR1 DNAH10 DPYSL4 FZD2 GGT7 LOC100129961 LRRC37A2 NFATC2IP RAD9A RP11-296I10.3 SLC5A11 SLC9A3R2 TSC2 YPEL3 Y_RNA ZBTB38
Current tobacco smoking 2.32 8 4 12.1 0.81 4.1e-03 ACTR1A ARL3 CYP17A1-AS1 RP11-332O19.5 SCAI SLC5A11 SUFU Y_RNA
Average weekly fortified wine intake 1.59 1 0 0.0 0.00 1.0e+00 SLC5A11
Maternal smoking around birth 2.37 6 2 6.1 0.99 6.2e-05 ACTR1A ARL3 CYP17A1-AS1 RP11-332O19.5 SLC5A11 TMEM180
Fed-up feelings 1.39 2 1 3.0 0.00 1.0e+00 CRHR1 LRRC37A2
Relative age voice broke 1.64 3 2 6.1 -0.87 1.3e-01 CRHR1 LRRC37A2 UQCC1
Age when periods started (menarche) 1.87 6 3 9.1 0.59 1.2e-01 ADCY3 NUCKS1 RP11-296I10.3 SLC22A5 YPEL3 Y_RNA
Heel bone mineral density (BMD) T-score, automated (left) 2.81 7 4 12.1 -0.16 7.3e-01 C7orf58 CRIPAK DNAH10 FZD2 GLDN JAG1 L3MBTL3
High blood pressure 1.65 8 4 12.1 -0.85 3.8e-03 DCAF16 JARID2 P4HA2-AS1 PDLIM4 SFXN2 SLC22A4 SLC22A5 SLC5A11
Hayfever, allergic rhinitis or eczema 2.03 6 4 12.1 -0.77 4.1e-02 C6orf106 P4HA2-AS1 SLC22A5 SUFU TMEM180 ZBTB38
Multivitamins +/- minerals 1.49 1 0 0.0 0.00 1.0e+00 NUCKS1
Supplements: Glucosamine 1.37 1 0 0.0 0.00 1.0e+00 ARHGDIB
Diverticular disease/diverticulitis (self-reported) 1.63 1 0 0.0 0.00 1.0e+00 FZD2
Sitting height 11.42 71 63 190.9 0.90 4.0e-29 ADCY3 AP001372.2 ARFGEF2 ARHGDIB AXIN2 BCKDHB BEND3P3 BRD3 C2CD3 C6orf106 CCDC53 CD79B CDC42SE2 CEP192 CRHR1 CRIPAK CRYL1 CYB561 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 IFT88 JAG1 JARID2 L3MBTL3 LOXL1-AS1 LRRC37A2 MAN2C1 MAP1LC3A NCOA1 NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PML POLD3 PPME1 PPP3R1 RAD9A RAPGEF6 RFT1 RP11-171I2.2 RP11-250B2.6 RP11-296I10.3 RP3-477O4.16 SLC22A4 SLC22A5 SLC9A3R2 SLFNL1 SNAP47 SUFU TFB1M TMEM180 TP53I3 TSC2 TSEN15 UQCC1 Y_RNA ZBTB38 ZCCHC24
High blood pressure (mother) 1.66 1 0 0.0 0.00 1.0e+00 TMEM106C
Body mass index (BMI) 3.02 18 9 27.3 -0.37 1.1e-01 ACTR1A ADCY3 ARFGEF2 ARL3 C6orf106 DNAH10 DPYSL4 L3MBTL3 LOC100129961 LOXL1-AS1 NFATC2IP PML RFT1 RP11-296I10.3 SLC5A11 SLC9A3R2 YPEL3 Y_RNA
Impedance of leg (left) 2.68 24 17 51.5 -0.51 6.3e-03 ACTR1A ADCY3 ANKRD11 CD79B CDC42SE2 CRHR1 CYBRD1 CYP17A1-AS1 DLEU1 DLEU7 GGT7 HOXB2 L3MBTL3 LOXL1-AS1 NFATC2IP NUCKS1 PLCD3 RAD9A RAPGEF6 RP3-477O4.16 SNAP47 TMEM106C UQCC1 YPEL3
Leg predicted mass (left) 7.53 51 40 121.2 0.91 2.2e-22 ACTR1A ANKRD11 ARL3 AXIN2 C6orf106 CD79B CDC42SE2 CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 L3MBTL3 LOXL1-AS1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Trunk fat mass 3.78 24 21 63.6 0.33 7.7e-02 ADCY3 ARL3 C6orf106 CRHR1 CYP17A1-AS1 DNAH10 DPYSL4 FZD2 GGT7 L3MBTL3 LOC100129961 LRRC37A2 NFATC2IP RAD9A RP11-296I10.3 RP3-477O4.16 SLC5A11 SLC9A3R2 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38
Waist circumference 3.03 16 11 33.3 0.10 6.9e-01 ADCY3 ARL3 C6orf106 CRIPAK CYP17A1-AS1 DPYSL4 GGT7 NFATC2IP RAD9A RP11-296I10.3 RP11-332O19.5 SLC5A11 SLC9A3R2 YPEL3 Y_RNA ZBTB38
Number of incorrect matches in round 2.38 4 1 3.0 -0.12 8.8e-01 CYP17A1-AS1 LOC100129961 NUCKS1 YPEL3
Past tobacco smoking 3.00 9 6 18.2 -0.68 2.1e-02 ACTR1A ADCY3 ARL3 CYP17A1-AS1 LRRC37A2 MAP1LC3A RP11-332O19.5 SUFU TMEM180
Alcohol usually taken with meals 1.68 1 0 0.0 0.00 1.0e+00 ACTR1A
Nervous feelings 2.13 6 4 12.1 -0.99 4.9e-07 ACTR1A ARL3 CRHR1 CYP17A1-AS1 LRRC37A2 YPEL3
Frequency of tenseness / restlessness in last 2 weeks 1.58 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Hearing difficulty/problems with background noise 1.43 3 1 3.0 0.00 1.0e+00 CRHR1 LRRC37A2 NUCKS1
Hair/balding pattern: Pattern 2 1.71 2 0 0.0 0.00 1.0e+00 CRHR1 LRRC37A2
Had menopause 1.04 1 0 0.0 0.00 1.0e+00 L3MBTL3
Forced vital capacity (FVC) 6.41 46 29 87.9 0.93 2.2e-22 ADCY3 AQP11 ARFGEF2 AXIN2 BCKDHB BEND3P3 C6orf106 CD79B CRHR1 CYB561 CYBRD1 CYP17A1-AS1 DCAF16 DLG5 FZD2 GGT7 HABP4 JAG1 L3MBTL3 LOC100129961 LOC441046 LOXL1-AS1 LRRC37A2 MAN2C1 NCOA1 PIP4K2B PML PPP3R1 RAD9A RP11-250B2.6 RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SCAI SLC9A3R2 SLFNL1 SNAP47 SRRT SUFU TMEM180 TP53I3 TSEN15 UQCC1 Y_RNA ZBTB38 ZCCHC24
Heel bone mineral density (BMD) T-score, automated (right) 2.71 7 3 9.1 -0.36 4.3e-01 C7orf58 CRIPAK DCAF16 DNAH10 FZD2 GLDN ZBTB38
Qualifications: None of the above 1.65 6 1 3.0 -0.45 3.7e-01 ACTR1A CEP192 NFATC2IP RFT1 SCAI SLC5A11
Mouth/teeth dental problems 1.31 1 0 0.0 0.00 1.0e+00 LRRC37A2
Allergy 2.25 9 7 21.2 0.86 1.4e-03 C6orf106 KIF1B P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5 SUFU TMEM180 ZBTB38
Fluid intelligence score 1.67 4 2 6.1 0.97 3.1e-02 CRHR1 DCAF16 NFATC2IP Y_RNA
Neuroticism score 1.99 3 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2 Y_RNA
Weight 5.59 41 33 100.0 0.78 5.8e-11 ACTR1A ADCY3 ARL3 C6orf106 CD79B CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DOT1L DPYSL4 DYM FAM45A FZD2 GGT7 GLDN L3MBTL3 MAP1LC3A NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 RAD9A RAPGEF6 RP11-332O19.5 RP3-477O4.16 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Impedance of arm (right) 2.53 23 15 45.5 -0.51 9.3e-03 ACTR1A ANKRD11 ARHGDIB ARL3 CD79B COPA CRHR1 CYBRD1 CYP17A1-AS1 DLEU1 DNAH10 DPYSL4 KIF1B L3MBTL3 LOXL1-AS1 LRRC37A2 NUCKS1 PPP3R1 RFT1 RP3-477O4.16 SLC9A3R2 TMEM106C YPEL3
Arm fat percentage (right) 3.67 17 11 33.3 -0.62 4.8e-03 ADCY3 ARFGEF2 BRD3 C6orf106 CD79B DCAF16 DNAH10 DPYSL4 FZD2 HABP4 LOC100129961 LRRC37A2 NFATC2IP RP11-296I10.3 SLC5A11 YPEL3 Y_RNA
Trunk fat-free mass 9.89 67 55 166.7 0.92 5.2e-30 ACTR1A ADCY3 ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 BTRC C6orf106 CCDC53 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A GGT7 GLDN HABP4 IFT88 JARID2 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PML PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24
Hip circumference 4.20 26 19 57.6 0.49 4.8e-03 ACTR1A ADCY3 ARL3 C6orf106 CD79B CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DNAH10 DOT1L DPYSL4 GGT7 GLDN L3MBTL3 LOC100129961 NFATC2IP RAD9A RP3-477O4.16 SLC5A11 SLC9A3R2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38
Father's age at death 1.39 1 0 0.0 0.00 1.0e+00 SLC22A5
Worrier / anxious feelings 2.92 8 7 21.2 -0.99 7.3e-09 ACTR1A ARL3 CRHR1 CYP17A1-AS1 LRRC37A2 RP11-332O19.5 SUFU TMEM180
Frequency of tiredness / lethargy in last 2 weeks 1.81 1 0 0.0 0.00 1.0e+00 POLD3
Hair/balding pattern: Pattern 3 2.30 3 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2 MAP1LC3A
Number of live births 1.16 1 0 0.0 0.00 1.0e+00 CRHR1
Forced expiratory volume in 1-second (FEV1) 5.52 38 19 57.6 0.93 1.1e-18 ADCY3 AQP11 ARFGEF2 AXIN2 BCKDHB C6orf106 CD79B CRHR1 CYB561 CYBRD1 CYP17A1-AS1 DCAF16 DLG5 FZD2 GGT7 HABP4 JAG1 L3MBTL3 LOC100129961 LOXL1-AS1 LRRC37A2 MAN2C1 P4HA2-AS1 RAD9A RP11-250B2.6 RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SCAI SLC22A5 SLC9A3R2 SLFNL1 SNAP47 TP53I3 UQCC1 Y_RNA ZBTB38 ZCCHC24
Pulse rate 2.63 5 3 9.1 0.60 2.8e-01 DLEU7 GIGYF1 SRRT TFR2 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.60 6 0 0.0 0.75 5.3e-02 ACTR1A ARFGEF2 CEP192 CRHR1 DCAF16 UQCC1
Mouth/teeth dental problems: Dentures 1.40 1 0 0.0 0.00 1.0e+00 ADCY3
Asthma 2.47 5 5 15.2 -1.00 2.4e-05 KIF1B P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
Medication: Cholesterol lowering 1.04 1 0 0.0 0.00 1.0e+00 TMEM106C
Forced expiratory volume in 1-second (FEV1), Best measure 5.23 28 16 48.5 0.95 1.1e-15 ADCY3 ARFGEF2 AXIN2 BRD3 C6orf106 CD79B CRHR1 CYB561 DCAF16 DLG5 FZD2 HABP4 JAG1 L3MBTL3 LOC100129961 LOXL1-AS1 LRRC37A2 MAN2C1 RAD9A RP11-250B2.6 RP11-296I10.3 SLC22A4 SLFNL1 TSEN15 UQCC1 Y_RNA ZBTB38 ZCCHC24
Impedance of arm (left) 2.51 23 15 45.5 -0.50 1.2e-02 ACTR1A ANKRD11 ARHGDIB ARL3 CD79B COPA CRHR1 CYBRD1 CYP17A1-AS1 DLEU1 DNAH10 KIF1B L3MBTL3 LOXL1-AS1 LRRC37A2 NUCKS1 PLCD3 RFT1 RP3-477O4.16 SLC9A3R2 TMEM106C TMEM180 YPEL3
Arm fat mass (right) 3.22 18 11 33.3 -0.04 8.6e-01 ADCY3 ARL3 C6orf106 CYP17A1-AS1 DNAH10 DPYSL4 FZD2 GGT7 L3MBTL3 LOC100129961 NFATC2IP RP11-296I10.3 SLC5A11 SLC9A3R2 UQCC1 YPEL3 Y_RNA ZBTB38
Trunk predicted mass 9.88 65 55 166.7 0.92 4.8e-30 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 C6orf106 CCDC53 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A GGT7 GLDN HABP4 IFT88 JARID2 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PML PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24
Standing height 12.09 78 70 212.1 0.91 3.3e-33 ADCY3 AQP11 ARFGEF2 ARL3 AXIN2 BCKDHB BEND3P3 BRD3 BTRC C6orf106 C7orf58 CCDC53 CD79B CDC42SE2 CEP192 CRHR1 CRIPAK CRYL1 CYB561 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A FZD2 GGT7 GLDN GNL3 HABP4 IFT88 JAG1 L3MBTL3 LOC441046 LOXL1-AS1 LRRC37A2 MAN2C1 MAP1LC3A NCOA1 NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PML PPP3R1 RAD9A RAPGEF6 RFT1 RP11-171I2.2 RP11-250B2.6 RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SRRT SUFU TFB1M TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24 ZNF607
Tense / 'highly strung' 1.41 2 0 0.0 0.00 1.0e+00 NUCKS1 YPEL3
Hair/balding pattern: Pattern 4 2.86 8 4 12.1 0.42 3.0e-01 CRHR1 DLG5 GGT7 KIF1B LRRC37A2 MAP1LC3A SLFNL1 ZBTB38
Birth weight of first child 2.16 3 1 3.0 0.00 1.0e+00 ARFGEF2 DCAF16 ZBTB38
Peak expiratory flow (PEF) 5.22 26 11 33.3 0.98 2.1e-22 ANKRD11 AQP11 C6orf106 CD79B CRHR1 CYP17A1-AS1 DCAF16 GGT7 LOXL1-AS1 LRRC37A2 MAP1LC3A NUCKS1 PML PPP1R21 RAD9A RP11-296I10.3 RP11-332O19.5 RP3-477O4.16 SCAI SLC9A3R2 SUFU TMEM106C TMEM180 TP53I3 UQCC1 Y_RNA
Qualifications: O levels/GCSEs or equivalent 1.12 1 0 0.0 0.00 1.0e+00 DPYSL4
Medication: Paracetamol 1.63 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Headache pain in last month 1.58 3 3 9.1 0.00 1.0e+00 ADAMTSL4 CRHR1 LRRC37A2
Medication for cholesterol, blood pressure or diabetes 1.17 2 0 0.0 0.00 1.0e+00 JARID2 TMEM106C
Hypothyroidism/myxoedema (self-reported) 1.08 1 1 3.0 0.00 1.0e+00 GIGYF1
Birth weight 2.25 6 1 3.0 0.48 2.7e-01 CYP17A1-AS1 DCAF16 L3MBTL3 NUCKS1 RFT1 Y_RNA
Forced vital capacity (FVC), Best measure 6.30 40 29 87.9 0.94 1.0e-20 ADCY3 ARFGEF2 AXIN2 BCKDHB BEND3P3 C6orf106 CD79B CRHR1 CYB561 CYP17A1-AS1 DCAF16 DLEU1 DLG5 FZD2 GGT7 HABP4 JAG1 L3MBTL3 LOC100129961 LOXL1-AS1 LRRC37A2 MAN2C1 NCOA1 PIP4K2B PML PPP3R1 RAD9A RFT1 RP11-250B2.6 RP11-296I10.3 RP3-477O4.16 SLFNL1 SNAP47 SRRT TP53I3 TSEN15 UQCC1 Y_RNA ZBTB38 ZCCHC24
Body fat percentage 3.38 21 12 36.4 -0.52 1.2e-02 ADCY3 ARFGEF2 BRD3 C6orf106 CD79B CEP192 DCAF16 DNAH10 DPYSL4 FZD2 HABP4 LOC100129961 LRRC37A2 NFATC2IP RP11-296I10.3 SLC5A11 SLC9A3R2 TSC2 YPEL3 Y_RNA ZBTB38
Leg fat percentage (right) 3.68 19 13 39.4 -0.60 3.3e-03 ADCY3 ARFGEF2 ARL3 BRD3 C6orf106 CD79B CEP192 DCAF16 DNAH10 DPYSL4 HABP4 LOC100129961 NFATC2IP RP11-296I10.3 SLC5A11 SLC9A3R2 UQCC1 YPEL3 Y_RNA
Arm fat-free mass (right) 8.62 63 48 145.5 0.92 2.9e-28 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 C2CD3 C6orf106 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DPYSL4 DYM FAM45A GGT7 HABP4 HMG20A IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Exposure to tobacco smoke outside home 2.47 2 0 0.0 0.00 1.0e+00 ACTR1A RP11-332O19.5
Comparative body size at age 10 6.18 9 6 18.2 -0.63 3.6e-02 ADCY3 BRD3 DOT1L NCOA1 NFATC2IP NUCKS1 PILRA YPEL3 Y_RNA
Number of full brothers 1.20 1 0 0.0 0.00 1.0e+00 LRRC37A2
Worry too long after embarrassment 1.45 2 0 0.0 0.00 1.0e+00 CRHR1 LRRC37A2
Wheeze or whistling in the chest in last year 1.44 1 0 0.0 0.00 1.0e+00 YPEL3
Age at first live birth 1.10 1 0 0.0 0.00 1.0e+00 DCAF16
Qualifications: College or University degree 1.89 12 5 15.2 0.41 1.7e-01 ACTR1A ARFGEF2 ARL3 BTRC CRHR1 DCAF16 HABP4 LRRC37A2 NFATC2IP PILRA SLC5A11 UQCC1
Medication for pain relief, constipation, heartburn 1.77 3 1 3.0 0.00 1.0e+00 CRHR1 FZD2 LRRC37A2
Neck or shoulder pain in last month 1.40 1 0 0.0 0.00 1.0e+00 YPEL3
Medication: Blood pressure 1.61 2 0 0.0 0.00 1.0e+00 DCAF16 JARID2
Angina (self-reported) 1.37 1 0 0.0 0.00 1.0e+00 GGT7
Migraine (self-reported) 1.55 2 0 0.0 0.00 1.0e+00 ADAMTSL4 SFXN2
Medication: Seretide 50 evohaler 1.65 4 0 0.0 -1.00 4.8e-05 P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
Mean time to correctly identify matches 1.77 4 1 3.0 0.23 7.7e-01 ARFGEF2 L3MBTL3 LRRC37A2 NUCKS1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.56 1 0 0.0 0.00 1.0e+00 LRRC37A2
Whole body fat mass 3.54 22 18 54.5 0.21 3.0e-01 ADCY3 ARL3 C6orf106 CYP17A1-AS1 DNAH10 DPYSL4 FZD2 GGT7 L3MBTL3 LOC100129961 LRRC37A2 NFATC2IP RAD9A RP11-296I10.3 SLC5A11 SLC9A3R2 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38
Leg fat mass (right) 3.30 19 12 36.4 0.06 7.9e-01 ACTR1A ADCY3 ARL3 C6orf106 CYP17A1-AS1 DNAH10 DPYSL4 GGT7 L3MBTL3 LOC100129961 NFATC2IP RAD9A RP11-296I10.3 SLC5A11 SLC9A3R2 TSC2 YPEL3 Y_RNA ZBTB38
Arm predicted mass (right) 8.56 61 48 145.5 0.92 7.3e-28 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BRD3 C2CD3 C6orf106 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DPYSL4 DYM FAM45A GGT7 HABP4 HMG20A IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Pulse rate, automated reading 3.37 10 6 18.2 0.18 6.2e-01 C2CD3 C6orf106 CRIPAK GIGYF1 GNL3 HABP4 LOC100129961 SRRT TFR2 ZBTB38
Alcohol intake frequency. 1.80 7 5 15.2 -0.71 7.4e-02 CRHR1 LRRC37A2 NFATC2IP PILRA TFR2 YPEL3 Y_RNA
Comparative height size at age 10 9.75 56 48 145.5 0.91 3.9e-25 ADCY3 ARFGEF2 AXIN2 BTRC C6orf106 CCDC53 CD79B CRHR1 CRIPAK CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A FZD2 GGT7 HABP4 L3MBTL3 LOXL1-AS1 LRRC37A2 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PML RAD9A RAPGEF6 RFT1 RP11-171I2.2 RP11-250B2.6 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC9A3R2 SLFNL1 SNAP47 SUFU TFB1M TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 Y_RNA ZBTB38 ZCCHC24
Suffer from 'nerves' 1.94 4 2 6.1 -0.47 5.3e-01 CRHR1 LRRC37A2 NFATC2IP Y_RNA
Overall health rating 1.73 3 1 3.0 0.00 1.0e+00 SCAI SLC5A11 TMEM106C
Knee pain experienced in last month 2.37 3 2 6.1 -1.00 3.4e-03 RP3-477O4.16 TMEM106C UQCC1
Hypertension (Self-reported) 1.66 9 4 12.1 -0.86 1.5e-03 DCAF16 JARID2 P4HA2-AS1 PDLIM4 SFXN2 SLC22A4 SLC22A5 SLC5A11 TSC2
Illnesses of father: Heart disease 1.45 1 0 0.0 0.00 1.0e+00 DNAH10
Smoking status: Previous 2.11 2 0 0.0 0.00 1.0e+00 RP11-332O19.5 SUFU
Forced expiratory volume in 1-second (FEV1), predicted 7.28 31 17 51.5 0.96 1.6e-20 ADCY3 AXIN2 C6orf106 CD79B CYP17A1-AS1 DCAF16 DLEU1 DLG5 DOT1L DYM GGT7 L3MBTL3 LOXL1-AS1 MAP1LC3A P4HA2-AS1 PDLIM4 PIP4K2B RAD9A RP3-477O4.16 SLC22A4 SLC22A5 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 Y_RNA ZBTB38 ZCCHC24
Whole body fat-free mass 9.04 62 51 154.5 0.91 2.6e-27 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 C6orf106 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg fat-free mass (right) 7.70 54 42 127.3 0.91 1.1e-23 ACTR1A ANKRD11 ARFGEF2 ARL3 AXIN2 C6orf106 CD79B CDC42SE2 CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 L3MBTL3 LOXL1-AS1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TFB1M TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Arm fat percentage (left) 3.70 17 13 39.4 -0.61 5.4e-03 ADCY3 ARFGEF2 BRD3 C6orf106 CD79B CEP192 DCAF16 DNAH10 DPYSL4 FZD2 LOC100129961 LRRC37A2 NFATC2IP RP11-296I10.3 SLC5A11 YPEL3 Y_RNA
Handedness (chirality/laterality): Left-handed 1.57 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Mood swings 1.71 4 2 6.1 -0.69 3.1e-01 CRHR1 LRRC37A2 NUCKS1 SLC5A11
Loneliness, isolation 1.54 2 0 0.0 0.00 1.0e+00 ARFGEF2 Y_RNA
Qualifications: nursing, teaching 1.17 1 0 0.0 0.00 1.0e+00 AXIN2
Mouth/teeth dental problems: Mouth ulcers 1.32 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Medication for cholesterol 1.36 1 0 0.0 0.00 1.0e+00 JARID2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.27 1 0 0.0 0.00 1.0e+00 ADAMTSL4
Breast cancer (self-reported) 1.48 1 0 0.0 0.00 1.0e+00 CYBRD1
Asthma (self-reported) 2.41 5 5 15.2 -0.99 3.8e-05 KIF1B P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
Osteoarthritis (self-reported) 1.99 1 1 3.0 0.00 1.0e+00 TGFA
Smoking status: Current 2.42 8 4 12.1 0.82 3.9e-03 ACTR1A ARL3 CYP17A1-AS1 RP11-332O19.5 SCAI SUFU TMEM180 Y_RNA
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.02 6 4 12.1 0.16 7.3e-01 CRHR1 JAG1 LRRC37A2 RP11-296I10.3 UQCC1 YPEL3
Whole body water mass 8.99 63 51 154.5 0.91 6.0e-28 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 C6orf106 CCDC53 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg predicted mass (right) 7.71 54 42 127.3 0.91 1.5e-23 ACTR1A ANKRD11 ARFGEF2 ARL3 AXIN2 C6orf106 CD79B CDC42SE2 CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 IFT88 L3MBTL3 LOXL1-AS1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SCAI SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Arm fat mass (left) 3.33 20 14 42.4 0.11 6.0e-01 ADCY3 ARL3 C6orf106 CYBRD1 CYP17A1-AS1 DNAH10 DPYSL4 FZD2 GGT7 L3MBTL3 LOC100129961 NFATC2IP RAD9A RP11-296I10.3 SLC5A11 SLC9A3R2 UQCC1 YPEL3 Y_RNA ZBTB38
Number of self-reported non-cancer illnesses 1.51 2 0 0.0 0.00 1.0e+00 P4HA2-AS1 SLC22A5
Average weekly champagne plus white wine intake 1.35 1 0 0.0 0.00 1.0e+00 CRHR1
Miserableness 1.67 4 1 3.0 -0.69 3.1e-01 CRHR1 LOXL1-AS1 LRRC37A2 Y_RNA
Guilty feelings 1.27 1 0 0.0 0.00 1.0e+00 CRHR1
Financial situation satisfaction 1.27 1 0 0.0 0.00 1.0e+00 BRD3
Medication: Blood pressure 1.72 5 1 3.0 -0.76 8.2e-02 CRHR1 P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
High cholesterol (Self-reported) 0.94 2 0 0.0 0.00 1.0e+00 DCAF16 TMEM106C
Medication: Bendroflumethiazide 1.62 4 1 3.0 -0.99 6.7e-04 P4HA2-AS1 PDLIM4 SLC22A4 SLC22A5
Medication: Paracetamol 1.69 2 2 6.1 0.00 1.0e+00 CRHR1 LRRC37A2
Alcohol drinker status: Never 0.86 1 0 0.0 0.00 1.0e+00 Y_RNA
Ever smoked 2.48 6 5 15.2 0.99 5.3e-06 ACTR1A ARL3 CYP17A1-AS1 RP11-332O19.5 SUFU TMEM180
Basal metabolic rate 8.29 57 45 136.4 0.91 2.4e-24 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BRD3 C6orf106 CD79B CDC42SE2 CRIPAK CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DOT1L DYM FAM45A FZD2 GGT7 GLDN HABP4 IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Leg fat percentage (left) 3.73 22 13 39.4 -0.61 1.3e-03 ADCY3 ARFGEF2 ARL3 BRD3 C6orf106 CD79B CEP192 DCAF16 DNAH10 DPYSL4 HABP4 LOC100129961 NFATC2IP PML RFT1 RP11-296I10.3 SLC22A5 SLC5A11 SLC9A3R2 UQCC1 YPEL3 Y_RNA
Arm fat-free mass (left) 8.31 60 45 136.4 0.91 1.2e-26 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BRD3 C2CD3 C6orf106 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A GGT7 HABP4 HMG20A IFT88 L3MBTL3 LOXL1-AS1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24
Irritability 1.46 4 1 3.0 -0.97 2.8e-02 CRHR1 L3MBTL3 LRRC37A2 PPP1R21
Ever had prostate specific antigen (PSA) test 1.46 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 2.18 3 0 0.0 0.00 1.0e+00 ARHGDIB C7orf58 LRRC37A2
Diastolic blood pressure, automated reading 1.81 11 6 18.2 -0.15 6.7e-01 DCAF16 GIGYF1 JAG1 LOC100129961 P4HA2-AS1 PDLIM4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SRRT
Ever depressed for a whole week 1.35 1 0 0.0 0.00 1.0e+00 CRHR1
Vascular/heart problems diagnosed by doctor 1.66 8 4 12.1 0.84 5.0e-03 DCAF16 JARID2 P4HA2-AS1 PDLIM4 SFXN2 SLC22A4 SLC22A5 SLC5A11
Cholesterol lowering medication 1.15 2 0 0.0 0.00 1.0e+00 DCAF16 DNAH10
Pain experienced in last month 1.25 2 0 0.0 0.00 1.0e+00 LRRC37A2 SCAI
Pack years of smoking 1.61 1 0 0.0 0.00 1.0e+00 CYB561
Impedance of whole body 2.58 30 18 54.5 -0.46 6.6e-03 ACTR1A ADCY3 ANKRD11 ARHGDIB ARL3 CD79B COPA CRHR1 CYBRD1 CYP17A1-AS1 DLEU1 DLEU7 DNAH10 GGT7 HOXB2 KIF1B L3MBTL3 LOXL1-AS1 LRRC37A2 NUCKS1 PLCD3 RAD9A RAPGEF6 RFT1 RP3-477O4.16 SNAP47 TMEM106C TSEN15 UQCC1 YPEL3
Leg fat mass (left) 3.34 20 13 39.4 0.06 7.8e-01 ACTR1A ADCY3 ARL3 C6orf106 CYP17A1-AS1 DNAH10 DPYSL4 FZD2 GGT7 L3MBTL3 LOC100129961 NFATC2IP RAD9A RP11-296I10.3 SLC5A11 SLC9A3R2 TSC2 YPEL3 Y_RNA ZBTB38
Arm predicted mass (left) 8.36 63 44 133.3 0.91 1.1e-27 ACTR1A ANKRD11 ARFGEF2 ARHGDIB ARL3 AXIN2 BCKDHB BRD3 C2CD3 C6orf106 CD79B CDC42SE2 CEP192 CRIPAK CRYL1 CYBRD1 CYP17A1-AS1 DCAF16 DLEU1 DLEU7 DLG5 DNAH10 DOT1L DYM FAM45A GGT7 HABP4 HMG20A IFT88 L3MBTL3 LOXL1-AS1 MAN2C1 MAP1LC3A NCOA1 NFATC2IP NUCKS1 P4HA2-AS1 PDLIM4 PIP4K2B PLCD3 PLCL1 PPP3R1 RAD9A RAPGEF6 RP11-250B2.6 RP11-332O19.5 RP3-477O4.16 SFXN2 SLC22A4 SLC22A5 SLC5A11 SLC9A3R2 SLFNL1 SNAP47 SUFU TMEM180 TP53I3 TSC2 TSEN15 UQCC1 YPEL3 ZBTB38 ZCCHC24

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 39 1.117 2.84
GTEx Adipose Visceral Omentum 21 1.031 2.85
GTEx Adrenal Gland 15 1.030 2.76
GTEx Artery Aorta 34 1.142 2.90
GTEx Artery Coronary 17 1.437 2.89
GTEx Artery Tibial 38 1.010 2.89
GTEx Brain Caudate basal ganglia 14 1.522 2.89
GTEx Brain Cerebellar Hemisphere 13 0.873 2.87
GTEx Brain Cerebellum 21 1.060 2.85
GTEx Brain Cortex 20 1.932 3.08
GTEx Brain Frontal Cortex BA9 14 1.515 3.01
GTEx Brain Hippocampus 7 1.336 3.07
GTEx Brain Hypothalamus 7 1.186 2.89
GTEx Brain Nucleus accumbens basal ganglia 12 1.387 3.26
GTEx Brain Putamen basal ganglia 6 0.962 3.03
GTEx Breast Mammary Tissue 24 1.216 2.85
GTEx Breast Mammary Tissue (Male) 17 1.425 3.02
GTEx Breast Mammary Tissue (Female) 20 1.217 2.66
GTEx Cells EBV-transformed lymphocytes 23 1.616 3.03
GTEx Cells Transformed fibroblasts 27 0.643 2.68
GTEx Colon Sigmoid 14 0.958 2.70
GTEx Colon Transverse 19 0.921 2.81
GTEx Esophagus Gastroesophageal Junction 13 0.900 2.83
GTEx Esophagus Mucosa 37 1.114 2.89
GTEx Esophagus Muscularis 30 0.928 2.72
GTEx Heart Atrial Appendage 15 0.950 2.89
GTEx Heart Left Ventricle 13 0.850 2.58
GTEx Liver 11 1.534 2.91
GTEx Lung 30 1.044 2.88
GTEx Muscle Skeletal 32 1.107 2.93
GTEx Nerve Tibial 43 0.995 2.82
GTEx Ovary 16 1.762 3.11
GTEx Pancreas 15 0.919 2.70
GTEx Pituitary 16 1.435 3.10
GTEx Prostate 9 1.078 2.86
GTEx Skin Not Sun Exposed Suprapubic 24 0.976 2.95
GTEx Skin Sun Exposed Lower leg 38 1.044 2.98
GTEx Small Intestine Terminal Ileum 8 1.735 2.86
GTEx Spleen 16 1.134 3.01
GTEx Stomach 18 1.238 2.89
GTEx Testis 39 1.236 2.86
GTEx Thyroid 42 1.050 2.74
GTEx Uterus 9 1.587 3.10
GTEx Vagina 8 1.260 3.00
GTEx Whole Blood 25 1.254 2.91
METSIM Adipose 30 0.651 2.50
NTR Blood 18 0.749 2.56
ROSMAP Brain Pre-frontal Cortex 30 0.683 2.65
YFS Blood 33 0.715 2.47
CommonMind Brain Pre-frontal Cortex 35 0.651 2.48
TCGA Breast Tumor 7 0.913 2.54
TCGA Breast Normal 27 0.642 2.45
TCGA Ovarian Tumor 23 0.787 2.29
TCGA Prostate Tumor 20 0.578 2.59