Hub : Genes

A4GALT

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1990 0.0470 3.0e-07 0.044 0.087 0.127 0.121 0.086 4.3e-06 9.1e-11 3.0e-15 1.7e-14 1.2e-10
2 GTEx Adipose Subcutaneous 0.1760 0.0550 3.3e-04 0.050 NA 0.148 NA 0.106 6.0e-05 NA 4.1e-12 NA 5.5e-09
3 GTEx Artery Aorta 0.2440 0.0690 1.2e-03 0.089 NA 0.027 NA -0.004 1.3e-05 NA 1.1e-02 NA 6.8e-01
4 GTEx Cells Transformed fibroblasts 0.3740 0.0630 2.6e-09 0.030 NA 0.177 NA 0.196 2.3e-03 NA 2.8e-13 NA 1.2e-14
5 GTEx Colon Sigmoid 0.2830 0.0920 1.4e-03 0.038 NA 0.043 NA 0.043 1.7e-02 NA 1.3e-02 NA 1.2e-02
6 GTEx Esophagus Mucosa 0.2500 0.0740 2.8e-05 0.095 NA 0.128 NA 0.079 6.7e-07 NA 6.8e-09 NA 6.0e-06
7 GTEx Esophagus Muscularis 0.3800 0.0620 9.6e-11 0.109 NA 0.252 NA 0.278 4.0e-07 NA 1.7e-15 NA 3.8e-17
8 GTEx Heart Atrial Appendage 0.1830 0.0730 8.9e-03 -0.006 NA -0.006 NA -0.006 7.4e-01 NA 7.2e-01 NA 9.6e-01
9 GTEx Heart Left Ventricle 0.1891 0.0610 1.1e-03 0.090 NA 0.052 NA 0.065 1.6e-05 NA 9.4e-04 NA 2.4e-04
10 GTEx Lung 0.1695 0.0542 2.9e-03 0.007 NA 0.032 NA -0.002 8.1e-02 NA 1.5e-03 NA 5.5e-01
11 GTEx Muscle Skeletal 0.2108 0.0561 4.9e-05 0.167 NA 0.151 NA 0.162 4.1e-16 NA 1.2e-14 NA 1.1e-15
12 GTEx Testis 0.3070 0.0780 1.6e-04 0.163 NA 0.246 NA 0.266 1.0e-07 NA 2.7e-11 NA 3.2e-12
13 GTEx Whole Blood 0.2000 0.0610 1.8e-03 0.071 NA 0.047 NA 0.043 4.2e-07 NA 3.5e-05 NA 7.4e-05
14 YFS Blood 0.3015 0.0336 0.0e+00 0.214 0.170 0.213 0.215 0.212 4.5e-68 4.4e-53 1.1e-67 1.5e-68 2.4e-67
15 TCGA Breast Invasive Carcinoma 0.0348 0.0155 6.9e-05 0.007 0.026 0.027 NA 0.011 1.1e-02 3.7e-06 2.8e-06 NA 2.0e-03
16 TCGA Colon Adenocarcinoma 0.0990 0.0380 1.0e-04 -0.004 0.063 0.023 NA 0.014 6.1e-01 1.6e-04 1.8e-02 NA 5.0e-02
17 TCGA Kidney Renal Clear Cell Carcinoma 0.0908 0.0463 1.7e-03 0.057 0.022 0.049 NA 0.052 5.3e-07 1.6e-03 2.9e-06 NA 1.5e-06
18 TCGA Brain Lower Grade Glioma 0.0911 0.0306 4.0e-07 0.013 0.074 0.069 NA 0.047 1.1e-02 7.9e-09 2.7e-08 NA 3.9e-06
19 TCGA Lung Adenocarcinoma 0.0448 0.0221 4.6e-03 0.009 0.021 0.013 NA 0.014 2.4e-02 1.5e-03 1.1e-02 NA 7.0e-03
20 TCGA Pancreatic Adenocarcinoma 0.1450 0.0630 3.8e-03 0.119 0.022 0.037 NA 0.062 1.1e-05 4.1e-02 1.1e-02 NA 1.3e-03
21 TCGA Prostate Adenocarcinoma 0.0745 0.0375 2.9e-03 0.034 0.041 0.022 NA 0.031 1.6e-04 3.8e-05 1.9e-03 NA 3.0e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.4 0.6 1.8 -0.7 1.1 1.2 0.1 1.2 0.4 0.7 1.4 1.1 0.1 0.7 0.7 0.1 -0.5 0.5 1.1 0.5 0.5 0.5 0.7 -0.3
Bipolar Disorder or Schizophrenia 0.2 0.4 1.8 -1.0 0.2 1.4 -0.2 0.1 -0.2 0.5 1.2 1.1 -0.1 0.4 -0.0 -0.2 -0.8 -0.6 0.7 -0.1 0.2 -0.4 0.7 0.4
Depressed Affect (Nagel 2018) 0.3 0.6 2.3 0.6 0.8 -0.9 1.1 0.1 -0.7 0.2 0.3 -0.1 -0.4 0.3 1.5 -0.6 -0.7 0.7 1.2 0.6 -0.1 1.2 0.4 -0.7
Depression (Nagel 2018) 1.1 1.7 5.8 0.2 1.4 0.8 0.4 0.7 -2.4 1.7 1.1 0.6 0.5 1.7 2.2 -0.2 -0.4 1.2 1.0 2.2 1.1 1.5 1.0 -1.6
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.4 -0.6 -1.5 -1.4 -1.2 -1.7 2.1 -0.3 -0.2 1.0 -1.8 -0.9 -1.1 0.1 0.1 0.2 0.8 -1.1 -1.5 -1.0 -1.2 0.8
Neuroticism (Nagel 2018) 0.3 0.8 4.2 -0.5 -0.9 -1.0 0.1 -1.0 0.2 -0.6 0.3 0.7 -1.0 -1.0 2.1 -0.2 -0.1 0.6 1.0 -0.6 -1.2 1.5 0.3 -0.9
Schizophrenia (2018) 0.2 0.3 1.3 -0.7 -0.8 0.7 -0.3 -0.8 -0.4 0.1 0.5 0.5 -0.5 -0.0 -0.6 -0.4 -0.6 -1.1 -0.0 -0.6 -0.2 -0.9 0.3 0.8
Schizophrenia vs Biploar Disorder 0.5 0.7 3.2 1.3 0.5 -0.0 0.8 -1.4 -0.2 0.7 0.6 -0.1 0.5 1.5 1.4 0.1 0.3 0.4 0.1 1.8 -0.2 0.8 0.0 -0.5
Worry (Nagel 2018) 0.6 1.2 4.7 -1.0 -1.6 0.6 -0.8 -0.8 1.2 0.3 1.1 1.9 -0.6 -0.6 2.2 0.9 0.8 0.5 0.6 -0.3 -0.8 1.2 1.0 -1.8
Alzheimer’s Disease (in mother) 0.7 0.9 4.2 0.5 -0.3 0.3 -0.5 1.1 -0.6 1.6 0.9 0.8 -0.2 1.3 1.2 0.5 0.5 -0.8 0.5 1.5 0.4 -0.1 0.8 -2.0
Alzheimer’s Disease (in father) 0.5 0.5 1.7 -0.2 -0.6 0.6 -1.3 -0.2 -0.5 1.3 0.1 0.4 -0.7 0.9 0.1 -0.9 -0.4 -0.5 -0.5 1.1 -0.0 -1.2 -0.4 -0.4
Alzheimer’s Disease (including proxy) 0.7 1.0 4.1 -0.2 -1.1 0.0 -1.2 0.1 -1.0 2.0 0.6 1.2 -1.3 0.9 1.1 -0.4 0.2 -0.8 0.3 1.3 -0.5 -1.0 0.5 -2.0
Crohns Disease (2017) 1.4 3.2 7.0 1.4 1.3 2.5 1.8 0.7 0.2 2.5 1.9 0.4 2.1 2.6 2.1 -0.7 -1.5 1.6 0.8 2.6 2.5 1.4 2.6 -0.4
Irritable Bowel Disease (IBD) 2.2 5.2 12.2 2.3 1.6 3.4 2.0 1.5 -0.5 3.5 3.0 0.9 2.2 3.4 2.0 -0.1 -1.3 1.9 1.7 3.2 2.5 1.6 3.3 -1.9
Ulcerative Colitis (UC) 2.4 4.6 10.7 2.3 1.6 3.2 1.6 1.3 -0.2 3.3 3.0 1.1 2.0 2.9 1.6 0.7 -0.5 1.7 2.1 2.7 1.7 1.7 2.9 -2.8
Major Depression (MDD) 0.7 0.9 5.0 0.1 -0.1 1.7 -0.6 -0.3 -0.2 0.0 1.6 0.0 0.0 0.0 1.4 0.0 1.2 0.0 0.1 1.8 -0.3 1.1 0.0 -2.2
Reaction Time 0.5 0.9 2.8 0.3 -0.8 -0.1 1.4 1.0 0.1 -0.6 -0.3 -0.7 1.1 0.6 1.1 -1.7 -1.7 0.6 0.4 1.0 0.4 0.9 0.9 1.6
Verbal and Numeric Reasoning (VNR) 1.1 2.7 8.3 -0.6 -1.3 -2.9 -0.6 -2.0 1.9 -2.4 -2.4 -1.1 -1.5 -2.0 -1.6 -0.5 0.2 -0.4 -0.7 -1.9 -1.6 -0.8 -2.7 1.3
Breast Cancer 3.8 9.2 23.1 1.4 4.3 3.7 1.5 -0.1 0.7 3.5 4.2 1.2 2.3 4.3 2.8 3.6 2.0 2.3 2.0 3.8 2.3 2.8 3.9 -4.8
Ovarian Cancer 2.1 2.8 9.8 -0.7 -1.1 -3.1 -1.3 -1.7 -1.7 -1.2 -1.8 -0.6 -1.6 -1.6 -2.7 0.3 1.0 -1.4 -1.5 -1.8 -0.5 -2.5 -2.4 0.9
Prostate Cancer 1.0 1.5 11.8 0.5 3.4 0.9 1.3 1.0 2.3 -0.7 -0.0 -1.2 0.7 1.1 -0.2 -0.7 -1.3 -0.0 -0.8 0.0 1.4 0.9 0.7 0.4
Age at First Birth 0.9 1.4 6.1 -0.4 0.7 -2.5 -0.8 -1.2 0.9 -0.4 -1.4 -1.0 -0.6 0.6 -1.0 -0.6 0.1 -1.1 -1.9 0.8 0.1 -2.0 -2.0 0.4
Bipolar Disorder (2011) 0.1 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 -0.3 -0.0 0.0 0.1
Body Mass Index (BMI) (2010) 0.5 0.7 2.1 -1.0 -0.0 -0.1 -1.2 -0.8 -1.3 0.9 0.7 1.5 -1.0 -0.6 -1.1 -0.3 -0.4 -0.9 0.0 -0.8 -0.4 -1.0 -0.0 -0.2
Coronary Artery Disease (CAD) 0.6 0.7 4.2 -1.0 -0.9 -0.4 -1.4 -1.0 1.3 0.0 -0.1 0.2 0.0 0.0 -1.1 0.0 2.0 0.0 -1.1 -0.4 -0.8 -0.3 0.0 -1.0
Crohns Disease (2012) 1.0 1.5 4.0 1.2 1.0 1.4 1.4 1.2 -0.4 1.2 1.3 0.1 0.9 1.9 1.4 -0.8 -1.4 0.9 0.5 2.0 1.7 0.9 1.7 -0.0
Mean Putamen Volume 0.7 0.8 3.9 -0.5 -1.1 0.2 -1.1 1.1 -1.6 0.7 -0.1 0.6 -0.4 0.1 -1.3 -1.1 -1.1 -1.0 -0.5 -0.1 0.7 -2.0 -0.6 0.5
Fasting Glucose 0.8 1.0 2.7 -1.6 -1.5 -0.3 -1.5 0.9 -1.3 -0.4 -0.1 0.6 -1.0 -0.9 -1.1 0.2 0.3 -0.3 0.1 -0.8 -1.1 -1.6 -1.6 0.2
HbA1C 3.5 3.9 10.7 1.8 2.5 1.6 1.9 0.5 1.6 1.0 1.6 0.2 1.6 2.0 2.2 3.1 2.7 0.5 1.2 2.0 0.3 2.8 2.6 -3.3
HDL Cholesterol 0.3 0.5 2.0 0.9 0.3 0.6 1.4 -1.4 -0.1 -0.4 -0.1 0.1 0.2 0.1 0.3 -0.6 -0.8 1.3 1.3 0.3 0.1 0.9 0.2 0.1
LDL Cholesterol 0.8 1.3 5.0 -0.3 1.1 -1.0 -0.8 -0.8 0.9 -1.1 -1.8 -2.0 -0.3 0.1 -0.9 0.5 1.0 -1.6 -2.2 0.4 0.3 -0.8 -2.2 -0.1
Lupus 2.9 4.4 10.3 1.8 1.7 2.5 2.9 1.4 0.9 1.7 2.2 -0.3 2.6 2.2 2.2 1.8 0.6 1.8 2.0 1.8 2.4 3.2 3.0 -2.6
Neuroticism (2016) 1.1 1.6 5.2 0.3 -1.4 -0.8 0.5 -2.1 1.1 -1.8 -2.1 -1.4 -0.6 -1.0 -1.0 -1.8 -1.2 -0.7 -0.6 -0.8 -0.9 -0.4 -1.4 2.3
Primary Biliary Cirrhosis 0.8 1.1 6.7 0.4 0.7 0.8 0.2 2.6 -2.0 0.4 0.7 1.0 0.2 0.3 1.3 -0.7 -0.7 1.4 1.4 0.6 -0.0 1.1 0.6 -1.0
Rheumatoid Arthritis 0.5 0.7 2.6 1.2 -0.5 1.3 1.6 -0.5 -0.0 0.5 0.4 -0.6 0.4 0.3 0.8 -0.7 -1.2 -0.4 0.2 0.1 1.3 -0.0 1.1 1.5
Schizophrenia (2014) 0.2 0.4 2.7 -0.6 -0.6 0.6 0.3 0.0 -0.9 -0.4 0.2 -0.2 -0.4 -0.4 -0.5 -0.3 -0.5 -0.7 -0.3 -1.0 0.1 -0.7 0.4 1.6
Triglycerides 0.3 0.5 1.6 -0.9 0.3 -0.7 -0.5 1.3 0.4 0.1 -0.9 -0.6 -0.8 -0.7 -0.3 -0.5 -0.0 -0.6 -0.4 -0.6 -0.0 -1.0 -1.1 0.3
Type 2 Diabetes (T2D) (2012) 0.3 0.4 1.4 -0.3 -0.2 0.4 0.4 1.2 -0.1 0.9 0.5 0.3 0.2 0.8 0.1 -0.9 -1.2 -0.5 -0.2 0.7 0.1 -0.7 1.0 0.1
Ulcerative Colitis 0.2 0.3 1.7 1.3 0.3 0.2 0.5 0.6 -0.6 -0.1 0.0 -0.4 0.0 0.6 -0.1 0.4 0.1 0.2 -0.2 0.5 0.4 0.6 0.2 -1.2
Blood Eosinophil Count 0.6 4.4 11.4 2.0 1.9 1.6 2.3 -0.6 -0.8 2.0 2.7 0.5 2.1 2.1 3.4 0.1 -1.1 2.6 1.5 1.9 2.4 2.8 2.9 -2.7
Blood Platelet Count 2.2 25.3 69.7 6.4 6.6 2.5 1.1 -2.0 5.3 2.0 2.2 -0.1 5.7 3.7 6.5 6.5 5.9 7.2 1.8 4.5 2.8 8.3 3.0 -8.3
Blood Red Count 8.4 81.1 163.8 -9.4 -7.3 -12.6 -5.5 -4.6 -3.8 -9.5 -11.6 -2.4 -11.3 -11.5 -10.1 -8.1 -3.1 -5.8 -6.2 -10.5 -9.0 -10.9 -12.8 11.0
Blood White Count 0.1 0.8 4.4 -0.5 -0.4 -1.0 0.4 1.6 -1.6 2.1 0.4 0.5 -0.7 0.6 -0.7 -0.6 -0.6 -0.9 1.2 0.1 -0.1 -0.9 -0.1 -1.2
Heel T-Score 0.3 2.0 14.5 -2.3 -3.8 -1.4 -1.5 -0.9 -0.2 -0.2 -0.0 1.4 -1.2 -1.4 -0.1 0.5 1.0 0.5 0.7 -1.2 -2.0 -0.4 -1.2 -1.6
BMI 0.4 2.3 7.6 -0.1 2.5 1.0 1.4 2.8 -1.6 2.2 0.9 0.2 0.6 1.7 0.3 -1.8 -2.4 1.1 1.8 1.4 1.7 -0.9 0.9 -0.0
Height 0.5 10.4 36.0 0.9 0.6 3.4 2.0 -1.2 -0.4 2.4 4.7 4.8 -1.3 -1.0 4.4 -2.9 -4.2 5.7 6.0 -1.1 -1.3 3.0 4.6 -0.1
Waist Hip Ratio (WHR) 0.7 3.4 16.8 -2.2 -2.4 -1.6 -1.8 0.6 -1.4 1.3 0.1 0.8 -1.9 -0.2 -2.9 -1.0 -0.8 -3.4 -1.6 -0.7 -0.5 -4.1 -0.7 2.1
Systolic Blood Pressure 0.4 2.2 10.3 -1.1 -1.0 1.0 -1.6 1.6 -1.3 -0.0 0.2 -0.1 0.5 1.1 -0.8 2.1 2.5 -3.2 -2.8 0.9 -0.5 -1.5 0.0 -1.0
Smoking Status 0.8 1.9 17.4 0.1 0.1 -0.7 -0.1 4.2 -1.3 2.8 0.9 0.8 1.0 1.0 0.1 -1.2 -1.8 -0.1 0.2 0.8 1.8 -0.3 0.8 0.4
Allergy or Eczema 0.9 2.4 6.1 0.5 1.0 1.0 1.1 0.6 -0.4 1.4 2.4 1.8 0.8 1.0 2.0 0.6 -0.2 2.5 2.4 0.9 -0.2 2.5 2.1 -2.5
Cardiovascular Disease 1.0 3.2 16.3 -3.0 -1.9 -0.8 -1.9 1.3 -2.0 0.4 -1.0 0.2 -1.5 -0.5 -2.5 -0.3 0.2 -2.7 -2.3 -0.6 -0.5 -4.0 -1.6 1.3
Hypothyroidism (self reported) 0.4 1.0 3.4 1.1 0.6 0.0 0.8 -1.5 0.3 -0.9 -0.9 -1.4 0.6 -1.2 -1.2 -0.4 -0.6 0.6 -1.2 -1.4 1.5 -0.1 -0.3 1.8
Respiratory disease 0.1 0.3 1.5 0.3 -0.3 -0.5 0.2 -1.0 -0.4 -0.1 0.5 0.2 -1.0 -0.3 -0.0 0.2 0.3 1.2 0.6 -0.3 -0.9 0.2 0.1 -0.9
Type 2 Diabetes (T2D) (2018) 1.4 2.7 12.1 -2.3 -2.0 -1.3 -2.3 -0.3 -2.0 0.3 -0.1 0.9 -2.2 -0.8 -1.6 -0.6 -0.4 -2.2 -1.7 -1.2 -1.0 -3.5 -1.1 1.4
Lung FEV1/FVC ratio 0.4 2.3 9.8 -2.5 -0.8 0.5 -2.0 1.2 1.8 2.1 1.1 1.6 -1.0 1.3 -0.9 -0.8 -0.9 -2.3 -0.9 1.2 -0.5 -3.1 -0.5 0.4
Lung FVC 1.0 4.9 13.4 -2.5 -2.9 -3.7 -2.0 -3.0 -0.7 -3.0 -2.4 0.6 -2.8 -3.3 -0.8 -0.7 0.5 -0.4 -0.6 -2.8 -3.1 -0.6 -2.7 1.1
Neuroticism 0.2 0.4 2.4 -0.1 -0.6 -0.4 -0.1 -1.4 0.7 -0.5 0.0 -0.2 -0.1 -0.5 1.6 0.4 0.5 -0.3 -0.4 -0.3 -0.3 1.1 0.4 -0.6
Chronotype (morning person) 0.5 1.2 5.2 -0.3 1.2 0.6 -0.2 -0.3 1.4 -1.7 -0.6 -1.2 0.6 -0.0 -0.9 1.8 1.9 -2.3 -1.2 -0.4 0.0 -0.3 -0.8 0.4
Hair Pigment 0.0 0.6 5.3 -0.5 -2.3 -0.3 -0.8 0.3 0.6 0.9 0.3 0.8 -0.6 0.3 -0.8 0.9 0.9 -0.1 0.3 0.4 -0.5 -0.5 -0.1 -0.3
Tanning 0.1 1.1 4.0 0.3 0.6 -0.7 -0.2 -0.7 -0.3 -1.8 -2.0 -1.3 -0.1 -1.0 -1.6 -0.0 0.6 -1.2 -1.4 -0.9 -0.8 -0.8 -1.8 0.9
Hand grip strength (left) 0.2 0.6 3.1 0.4 1.3 1.8 -1.1 -1.0 -0.5 0.2 0.0 0.5 -0.4 -0.3 -0.5 0.9 1.2 -0.7 -0.7 -0.2 -0.4 -0.5 -0.4 -0.8
Number of treatments/medications taken 0.4 0.7 1.7 0.1 1.1 -0.5 1.3 0.5 -1.0 0.7 0.7 0.1 0.7 -0.2 0.8 -0.6 -1.1 1.1 1.1 -0.4 0.6 1.3 1.3 -0.8
Average weekly spirits intake 0.6 0.8 4.0 -0.2 -0.4 -1.0 0.2 1.0 -0.2 -0.2 -0.2 0.3 0.2 -1.6 0.3 -0.5 -0.6 1.7 2.0 -1.4 -0.1 1.2 -0.2 0.4
Sensitivity / hurt feelings 0.4 0.6 2.6 0.8 -0.2 -1.4 0.3 -1.0 1.2 -0.8 -1.3 -1.6 -0.4 0.0 -0.0 0.3 1.0 -0.5 -0.5 0.2 0.2 0.1 -0.8 0.3
Frequency of depressed mood in last 2 weeks 1.6 2.3 5.8 1.6 2.0 1.2 1.3 1.1 -0.6 1.5 0.6 -0.4 1.4 2.0 2.3 0.4 0.2 1.9 0.9 2.4 1.6 2.2 1.3 -1.9
Hearing difficulty/problems: Yes 1.0 1.6 7.5 -1.5 -2.7 0.5 -1.7 -0.8 -0.2 0.5 1.3 1.7 -1.3 -0.8 -0.3 1.8 1.6 -0.7 -0.1 -1.0 -1.3 -1.0 0.6 -1.3
Relative age of first facial hair 0.7 1.4 6.4 1.6 1.1 -0.9 0.7 -2.5 0.8 -0.7 -1.3 -2.4 0.6 0.6 -0.2 0.4 0.5 -1.2 -2.0 0.7 1.4 -0.3 -0.4 0.7
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 6.6 -0.1 -0.9 -2.6 -1.6 -0.8 0.8 -0.3 -1.0 -0.1 -1.0 0.3 -1.6 0.8 1.5 -1.4 -1.7 0.4 -0.8 -1.0 -1.5 -0.2
Ever used hormone-replacement therapy (HRT) 1.2 1.6 4.2 0.2 1.6 0.7 0.3 1.6 -0.4 2.0 2.0 1.3 0.7 1.1 0.9 0.6 -0.2 1.8 1.6 0.8 1.7 0.7 1.4 -1.5
Ever had hysterectomy (womb removed) 0.5 0.5 1.8 0.2 0.3 0.4 0.3 0.6 -0.4 0.1 1.1 0.3 0.8 1.3 1.1 0.5 -0.1 -0.0 1.0 1.2 -0.1 0.8 1.3 -0.4
Systolic blood pressure, automated reading 0.5 1.4 6.5 0.1 0.2 1.0 0.2 2.5 -2.2 -0.3 0.1 -0.9 1.2 0.8 -0.3 1.7 1.6 -2.2 -1.4 0.6 0.3 -0.5 0.5 -1.0
Eye problems/disorders: Diabetes related eye disease 1.1 1.2 5.0 -0.4 0.2 -1.1 -1.7 1.4 -1.4 -0.7 -0.4 0.5 -1.1 -0.3 -0.3 1.6 2.2 -0.4 -1.5 0.0 -0.9 -0.0 -0.7 -1.7
Angina 1.1 1.4 5.1 -0.2 -0.2 1.7 -0.1 1.2 0.0 2.3 2.2 1.8 0.9 0.8 0.8 -0.1 -0.8 0.6 2.0 0.5 0.2 0.2 1.9 -0.6
Medication for hormone replacement therapy 1.7 1.9 4.6 1.0 1.2 1.9 1.0 -0.2 1.0 1.2 1.6 0.1 2.2 1.3 1.4 1.5 0.9 1.9 0.5 1.3 1.4 1.7 1.6 -2.0
Vitamin and mineral supplements 0.6 0.8 2.9 -1.2 -0.4 -0.5 -1.1 0.4 -0.2 -1.1 -0.3 0.4 -1.0 -0.6 -0.9 -0.1 0.1 -1.6 -1.0 -0.8 -1.7 -1.5 -0.8 1.1
Supplements: Zinc 0.9 1.0 4.2 0.2 -0.7 0.7 1.0 1.9 -0.7 0.8 1.0 0.4 0.6 -0.0 0.6 -1.3 -2.1 0.1 0.8 -0.2 1.3 0.3 1.4 1.2
Medication: Co-codamol 1.3 1.4 3.8 -1.9 -1.8 -1.6 -1.5 1.3 -1.2 -0.2 -0.3 1.1 -1.2 -1.8 -1.0 0.4 0.5 -0.0 0.9 -1.9 -1.4 -0.9 -1.1 0.2
Medication: Metformin 0.3 0.4 2.2 -0.2 -0.3 0.1 0.5 0.0 -1.5 -0.9 -0.3 -0.3 -0.6 -0.9 0.3 -0.8 -0.8 0.3 -0.4 -0.8 -0.3 -0.4 0.2 0.4
Diabetes (father) 1.3 1.6 6.4 -0.1 0.5 1.1 -0.6 1.5 -0.3 1.5 1.2 0.2 1.4 1.8 0.3 2.2 1.8 -1.1 -0.9 1.7 1.0 0.2 0.8 -2.5
Diabetes (mother) 1.2 1.5 7.1 -0.1 -0.6 -0.8 -0.9 0.4 -0.9 -1.1 -1.7 -1.0 -1.3 0.2 -1.6 -0.7 -0.1 -2.7 -2.2 0.4 -0.9 -1.6 -1.4 1.2
Severe depression (siblings) 2.6 2.9 8.5 2.9 1.9 1.8 2.4 0.4 -0.7 -0.0 0.5 -2.0 2.8 1.5 1.0 2.0 1.2 0.1 -0.4 1.4 2.1 2.5 1.8 -1.6
Pack years adult smoking proportion 0.3 0.5 2.3 -1.0 -0.1 0.4 -1.1 1.5 -0.6 0.7 0.4 0.4 -0.1 -0.2 -0.8 0.8 0.7 -1.1 0.3 -0.1 -0.1 -1.0 -0.5 0.1
Impedance of leg (right) 0.2 0.8 2.1 0.3 -0.5 0.0 -0.6 -0.4 1.4 1.4 1.5 1.3 0.3 1.3 0.8 0.6 0.5 0.5 -0.2 1.4 0.4 -0.0 1.1 -0.9
Leg fat-free mass (left) 0.5 2.6 8.8 0.0 1.0 1.6 2.1 0.9 -2.2 0.7 0.9 0.8 -0.0 -1.2 1.3 -2.3 -2.9 2.5 3.0 -1.3 0.2 1.1 1.6 1.0
Trunk fat percentage 1.1 4.5 15.9 0.1 0.9 0.7 1.3 2.9 -1.3 3.3 2.8 2.3 -0.3 1.5 2.8 -0.9 -1.7 3.0 4.0 1.7 0.4 1.0 2.3 -2.9
Hand grip strength (right) 0.3 0.8 6.5 0.8 2.0 2.5 -0.6 -0.7 0.2 0.9 0.4 0.3 0.4 0.4 -0.7 0.8 0.8 -0.1 -0.5 0.3 0.3 -0.2 -0.2 -1.1
Townsend deprivation index at recruitment 0.7 1.0 3.9 0.6 0.3 1.5 1.6 0.8 0.8 0.1 0.4 0.3 0.8 -0.6 0.8 -0.9 -1.2 1.5 1.2 -0.6 0.5 2.0 1.2 0.6
Current tobacco smoking 1.5 2.5 12.1 -0.2 0.1 1.1 -0.6 3.4 -2.3 3.5 1.9 1.7 0.6 1.9 0.8 -1.0 -1.5 -0.6 0.3 1.9 1.2 -0.7 1.6 -0.2
Average weekly fortified wine intake 1.3 1.5 8.9 0.5 0.9 -0.7 -0.0 -1.9 3.0 0.4 1.1 -0.2 1.1 0.5 -0.2 2.3 1.7 0.1 0.9 0.2 0.6 0.9 0.2 -2.2
Maternal smoking around birth 0.8 1.1 3.4 1.2 1.8 0.2 1.3 1.3 -1.2 1.2 -0.1 -0.6 0.8 1.0 0.5 -1.5 -1.6 0.5 -0.4 1.2 1.3 -0.3 0.9 0.8
Fed-up feelings 0.6 1.1 2.5 1.1 1.2 0.0 0.9 0.1 -0.6 1.2 1.2 0.4 0.4 1.4 1.4 0.1 -0.2 1.3 1.6 1.4 0.7 1.3 1.1 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 6.0 -0.8 -0.4 -0.5 -0.8 0.8 -2.4 1.2 1.1 2.1 -1.3 0.6 1.8 -0.7 -0.7 1.4 1.9 1.0 -0.9 0.6 0.6 -1.2
Relative age voice broke 0.7 1.0 3.6 0.6 1.7 0.6 0.4 -1.8 1.9 -1.1 0.0 -1.5 0.7 0.0 1.5 1.2 0.9 0.5 -0.5 0.1 0.3 1.2 -0.0 -0.6
Taking other prescription medications 0.9 1.5 4.5 0.3 1.2 -0.0 1.1 -1.2 -0.2 1.4 1.7 0.7 0.3 0.2 1.8 -0.3 -1.2 2.1 1.8 0.1 1.1 1.5 1.9 -1.2
Age when periods started (menarche) 0.9 2.1 11.3 1.7 2.1 0.5 -0.7 -2.1 3.4 0.0 0.4 -0.1 0.8 1.4 0.8 2.0 2.0 -0.1 -0.7 1.6 0.9 1.2 0.1 -1.9
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 3.9 -0.1 -0.8 -0.8 -0.7 -0.2 -2.0 -1.2 -1.0 -0.0 -1.3 -0.7 -1.1 -1.2 -0.8 -1.4 -0.4 -0.7 -1.2 -1.4 -0.9 2.0
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 5.7 1.2 0.0 1.1 1.4 0.0 0.2 0.1 1.2 -0.0 1.7 0.7 1.7 1.6 1.2 1.3 0.8 0.8 0.6 2.4 1.6 -2.3
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 3.9 -1.0 -0.3 -1.7 -0.1 -1.7 0.1 -0.9 -0.4 0.6 -1.0 -1.6 0.4 -1.5 -1.3 2.0 0.8 -1.4 -0.2 0.3 -0.3 1.6
Qualifications: CSEs or equivalent 0.4 0.5 2.0 0.5 1.0 -0.1 0.7 1.1 -1.4 -0.3 -0.1 -0.6 0.7 1.1 0.6 0.3 0.4 0.0 -0.5 1.3 0.3 0.7 0.5 0.3
Serious illness, injury or assault to yourself 0.5 0.6 1.7 -1.0 -0.7 -1.3 -0.5 0.4 -0.9 0.1 0.4 0.8 -1.1 -0.3 0.0 -1.0 -1.1 -0.3 -0.0 -0.5 -0.2 -1.3 0.4 1.0
High blood pressure 0.4 1.2 4.7 -1.7 -0.6 0.6 -0.6 2.2 -2.0 -0.3 -0.1 -0.6 0.0 0.1 -0.8 1.2 1.2 -1.7 -1.6 0.0 0.0 -1.6 -0.1 -0.6
Hayfever, allergic rhinitis or eczema 0.6 1.3 4.1 0.3 0.5 0.3 0.4 0.2 0.2 1.5 2.0 1.9 -0.1 0.6 1.3 -0.2 -0.8 1.7 2.0 0.6 -0.1 1.3 1.5 -1.5
Multivitamins +/- minerals 0.4 0.5 2.7 0.4 -0.4 -0.1 0.6 -0.0 -0.5 1.1 0.3 0.1 0.5 0.2 0.6 -0.7 -0.9 1.1 0.6 0.3 1.6 0.9 0.5 0.1
Stomach or abdominal pain in last month 1.5 1.9 7.2 2.7 2.3 0.8 1.2 0.5 1.5 1.6 -0.0 -0.8 2.0 1.4 -0.1 -0.2 -0.4 1.4 1.0 1.5 2.3 1.7 0.3 -0.6
Supplements: Glucosamine 1.3 1.6 6.5 -0.3 -1.0 -1.0 0.4 -0.1 1.5 -0.9 -0.8 0.2 -0.5 -2.3 -0.9 -1.8 -2.0 1.3 0.5 -2.6 0.3 0.3 -0.8 2.4
Diverticular disease/diverticulitis (self-reported) 3.1 3.7 8.5 1.0 1.4 2.1 2.1 2.7 -0.6 2.1 2.0 0.3 2.5 0.8 2.3 -0.4 -1.3 2.9 2.7 0.7 2.7 2.3 2.5 -1.1
Medication: Atenolol 0.6 0.8 3.5 -1.2 0.1 0.8 0.1 0.9 -0.2 1.3 1.0 0.9 0.9 -0.4 0.3 0.1 -0.0 1.4 1.9 -0.5 0.7 1.1 0.5 -1.2
Medication: Levothyroxine sodium 1.3 2.2 6.4 -0.0 -0.2 -2.0 0.2 -1.1 0.8 -1.6 -1.9 -1.6 -0.4 -1.7 -2.2 -1.6 -1.3 -0.7 -1.7 -1.9 0.6 -1.5 -1.7 2.5
Sitting height 1.1 8.0 34.0 1.2 1.7 3.5 3.1 -1.3 1.2 1.0 3.2 2.4 1.0 -1.2 3.9 -0.4 -1.7 5.8 5.3 -1.3 0.2 4.5 3.9 -1.4
Chronic bronchitis/emphysema (father) 3.0 3.5 8.8 0.7 2.1 1.2 0.2 0.1 0.4 2.3 2.6 1.0 1.4 2.8 2.4 1.9 1.0 1.8 1.3 2.7 1.7 2.2 2.4 -3.0
High blood pressure (mother) 1.2 1.6 6.0 -1.8 -0.5 0.3 -2.0 0.3 -0.7 0.1 -0.3 0.7 -2.1 0.1 -1.6 0.8 1.2 -2.1 -0.5 0.0 -1.5 -2.5 -1.7 -0.9
Body mass index (BMI) 0.3 1.3 6.8 -0.4 1.4 0.3 1.1 2.6 -1.9 1.5 0.5 0.1 0.3 0.6 0.4 -1.1 -1.5 1.0 1.9 0.5 0.7 -0.3 0.4 -0.6
Impedance of leg (left) 0.3 1.6 5.0 0.4 -0.4 0.3 -0.8 -0.9 2.2 1.6 2.0 1.9 0.1 1.7 1.3 1.2 1.0 0.8 0.5 1.8 -0.0 0.5 1.4 -1.6
Leg predicted mass (left) 0.5 2.5 8.6 0.0 1.0 1.5 2.2 0.8 -2.2 0.7 0.9 0.7 0.0 -1.1 1.4 -2.3 -2.9 2.6 2.9 -1.2 0.2 1.1 1.5 0.9
Trunk fat mass 1.1 4.7 17.2 0.5 1.5 1.3 2.1 2.6 -1.6 3.1 2.7 1.8 0.1 1.3 2.9 -1.1 -2.0 3.3 4.1 1.4 0.8 1.3 2.6 -2.3
Waist circumference 0.4 1.3 6.0 -0.7 0.6 -0.3 1.2 2.0 -2.4 1.6 0.4 0.2 -0.4 0.2 0.2 -1.9 -2.2 0.8 1.5 0.2 0.5 -1.1 0.5 0.1
Number of incorrect matches in round 0.4 0.7 3.1 0.1 0.4 1.3 0.6 0.2 -0.5 -0.0 1.4 -0.0 0.7 1.2 0.2 1.5 0.8 -1.4 -0.7 0.7 -0.1 0.0 1.8 -0.1
Past tobacco smoking 0.3 0.6 2.7 -0.5 0.1 0.2 -0.9 -0.7 -0.7 -1.5 -0.5 -0.2 -0.2 -0.4 -0.3 1.2 1.6 -0.8 -0.7 -0.2 -1.6 -0.4 -0.4 0.3
Alcohol usually taken with meals 0.7 1.1 2.7 -0.2 1.2 0.8 -1.6 -0.6 1.4 -1.5 -0.6 -0.1 -0.0 -0.4 -1.2 0.8 1.2 -1.6 -1.4 -0.7 -1.6 -0.3 -1.1 -0.4
Nervous feelings 0.6 1.2 7.4 -1.8 -2.7 -0.2 -1.3 -0.4 0.7 1.0 0.9 1.7 -1.6 -0.5 1.0 -0.7 -0.5 0.1 0.1 -0.1 -1.1 -0.8 0.0 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.7 0.7 0.8 -0.2 0.7 -0.9 -0.1 0.8 -0.2 -0.8 0.8 1.2 1.4 -1.0 -0.8 1.0 -0.1 1.6 1.2 0.9 0.3 -0.8
Hearing difficulty/problems with background noise 1.0 1.6 5.5 -1.5 -2.2 0.1 -2.3 -1.9 1.3 0.4 0.9 1.6 -1.1 -0.3 -0.3 1.5 1.5 -1.2 -0.8 -0.6 -1.2 -1.1 0.3 -0.5
Hair/balding pattern: Pattern 2 0.3 0.4 2.0 -0.6 1.4 -0.1 -0.4 1.3 -0.7 -0.9 -0.4 -0.0 -0.5 -0.2 0.0 0.6 1.0 -0.6 -0.4 -0.2 -0.5 -0.4 -0.5 -0.1
Had menopause 0.5 0.7 2.5 -1.1 0.3 0.7 0.9 1.1 0.4 -0.2 1.1 0.6 0.3 -0.9 0.5 0.1 -0.7 0.4 1.6 -1.4 0.2 0.4 1.3 -0.0
Had other major operations 1.8 2.2 7.0 -1.8 -2.0 -0.7 -0.8 0.3 2.1 2.6 1.4 2.6 -1.2 -1.0 -0.6 -1.6 -2.2 0.9 2.2 -1.2 0.1 -0.4 0.5 -0.5
Forced vital capacity (FVC) 0.6 2.5 6.3 -1.4 -1.7 -1.0 -0.8 -1.7 -0.6 -1.1 0.5 2.3 -2.3 -2.5 0.9 -1.0 -1.0 2.0 1.6 -2.3 -2.5 0.5 0.1 1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.0 5.1 1.5 0.1 0.7 1.5 -0.8 0.3 -0.6 0.1 -0.8 1.4 0.2 1.2 0.7 0.8 1.4 0.1 0.4 0.6 2.2 0.6 -1.5
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 2.2 0.7 0.2 0.6 0.4 -0.0 0.7 0.8 0.5 -0.4 0.9 0.3 -0.7 1.5 1.0 -0.9 -0.5 -0.3 1.4 0.2 0.6 -0.8
Qualifications: None of the above 0.2 0.5 4.6 0.0 0.6 0.2 -0.1 2.1 -0.3 0.6 0.1 0.4 0.7 0.2 0.3 -0.5 -0.6 0.9 0.7 0.3 0.6 1.0 0.2 0.4
Financial difficulties in last 2 years 1.3 1.7 5.4 1.3 0.7 1.0 1.9 1.2 -1.4 1.4 0.9 -0.5 0.8 0.7 1.6 -0.9 -1.2 2.3 0.8 0.8 2.3 1.3 1.4 -0.5
Mouth/teeth dental problems 1.5 2.3 8.0 0.3 -0.6 0.9 0.8 -1.1 1.5 0.4 1.9 1.6 0.2 -0.3 2.0 0.9 0.2 2.6 2.8 -0.5 -0.9 2.8 1.9 -2.2
Heart attack 1.2 1.6 7.4 -1.3 0.1 0.8 -0.4 1.5 -0.5 2.7 1.9 2.0 0.1 0.6 0.6 -1.7 -2.1 0.6 1.0 0.5 0.4 -1.2 1.5 -0.0
Allergy 0.7 1.6 9.2 0.7 0.3 0.1 1.2 0.3 -0.4 -1.8 -2.4 -3.0 1.3 -0.5 -0.6 -0.3 0.1 -1.5 -1.9 -0.4 1.1 -0.4 -0.8 1.8
Pain all over the body in last month 0.4 0.4 1.7 -0.9 -0.7 0.2 -0.1 -0.6 -1.1 -0.3 -0.1 0.6 -0.4 -0.7 -0.4 -1.3 -1.3 -0.1 0.3 -0.8 -0.7 -0.2 -0.0 0.9
Diabetes (self-reported) 0.8 1.3 4.7 -1.7 -1.7 -0.8 -1.5 -0.8 -1.1 -0.2 -0.0 0.7 -2.2 -0.9 -0.7 -0.5 -0.4 -1.0 -0.7 -1.2 -1.0 -2.1 -0.7 0.3
Hayfever/allergic rhinitis (self-reported) 1.9 2.5 7.7 1.0 0.6 1.2 0.9 1.9 -1.6 1.4 2.4 1.8 1.4 1.6 1.8 0.3 -0.5 2.2 1.5 1.5 0.2 2.2 2.8 -1.0
Medication: Ramipril 0.4 0.5 2.0 -1.1 -0.3 -0.2 -0.1 0.8 -1.4 -0.6 -0.0 0.1 -0.8 -0.9 -0.1 -1.0 -0.8 -0.2 -0.1 -0.8 -0.5 -0.9 0.2 0.4
Medication: Simvastatin 0.6 0.9 4.6 -0.1 -0.3 0.1 -0.8 -0.4 -0.2 -0.1 -0.3 -0.1 -0.6 -0.5 -1.2 1.9 2.2 -1.4 -0.3 -0.8 -0.0 -1.1 -1.0 -1.5
Fluid intelligence score 0.8 1.7 5.6 -0.1 -0.2 -1.5 -1.0 -1.9 0.6 -1.2 -1.8 -0.9 -1.5 -0.9 -1.7 0.1 1.0 -1.7 -1.3 -0.8 -1.7 -1.9 -2.4 0.3
Illnesses of siblings 1.1 1.6 5.8 0.1 -0.5 0.6 1.3 0.8 0.9 0.3 1.4 1.1 0.5 -0.3 2.4 -1.4 -1.8 0.9 2.3 -0.3 -0.5 1.9 2.0 0.7
Neuroticism score 0.1 0.2 1.3 -0.2 -0.5 -0.4 -0.2 -0.7 0.9 0.2 0.4 0.5 -0.3 -0.1 1.1 -0.1 -0.0 -0.1 0.3 0.1 -0.4 0.7 0.5 -0.3
Weight 0.7 3.5 13.8 0.3 1.8 1.8 2.4 1.6 -1.6 1.9 1.9 1.2 0.5 0.2 2.2 -1.7 -2.6 3.2 3.7 0.1 0.7 1.5 2.2 -0.7
Impedance of arm (right) 0.2 0.9 2.9 0.5 -1.5 -1.1 -0.3 -0.2 0.8 0.3 1.0 1.1 -0.4 1.1 1.7 0.1 0.1 -0.1 0.2 1.5 -1.0 0.5 1.2 -1.5
Arm fat percentage (right) 0.5 2.1 10.1 -0.5 0.7 -0.0 1.0 3.2 -1.9 2.0 1.4 1.0 0.2 1.2 1.6 -0.9 -1.4 1.4 2.4 1.3 0.4 0.2 1.2 -1.8
Trunk fat-free mass 0.3 1.9 4.9 0.0 1.4 1.9 1.9 -0.5 -1.6 -0.3 0.3 0.1 0.4 -1.8 0.5 -1.7 -2.2 1.8 2.0 -2.0 0.3 0.8 1.0 1.8
Hip circumference 0.5 2.0 6.0 0.4 2.1 1.1 2.3 1.2 -1.5 1.4 0.7 -0.0 0.7 0.6 1.6 -1.4 -1.9 2.4 2.4 0.7 1.1 0.8 1.2 -0.9
Time employed in main current job 0.4 0.5 1.8 -0.2 0.3 0.4 0.2 -0.8 -0.1 0.6 0.5 1.0 -1.3 0.0 0.5 -0.1 0.1 0.9 1.4 0.1 -1.0 -0.3 0.7 -0.9
Alcohol intake versus 10 years previously 1.5 2.3 7.3 0.8 2.4 2.0 0.5 1.8 1.4 2.3 1.0 -0.7 1.8 2.5 0.6 -0.2 -0.7 -0.2 -0.1 2.4 2.7 0.3 0.9 -0.6
Father’s age at death 0.8 1.1 3.7 1.4 -0.4 -0.0 -0.5 -1.3 1.9 0.7 -0.8 -0.7 0.5 0.1 -1.9 1.3 1.4 -0.8 -0.7 -0.0 1.0 -0.8 -1.6 -0.9
Worrier / anxious feelings 0.4 0.8 3.9 -0.7 -0.7 -0.7 -0.7 -1.8 2.0 -0.6 0.0 0.7 -0.8 -1.1 0.4 0.5 0.8 0.2 0.4 -1.2 -1.1 0.6 -0.1 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.5 9.3 -1.5 -0.3 -1.6 -0.9 0.9 -3.0 0.8 0.2 0.9 -2.0 -0.2 1.2 -1.7 -1.4 0.4 0.1 0.2 -1.3 -1.0 -0.2 -0.5
Falls in the last year 0.7 0.9 4.8 -0.2 -0.5 -0.5 1.2 -1.0 -0.8 0.1 -0.2 0.0 -0.6 -1.3 0.3 -2.2 -2.1 0.8 0.3 -1.2 0.5 -0.3 0.4 1.1
Hair/balding pattern: Pattern 3 0.5 0.8 3.2 0.9 0.5 0.6 1.8 0.4 1.8 -1.1 -0.7 -1.1 0.6 -0.9 0.1 0.2 -0.0 0.9 0.6 -1.1 0.4 1.3 0.5 0.2
Number of live births 0.3 0.5 2.4 -0.6 -0.5 0.9 -0.7 0.3 -0.7 0.9 0.6 1.0 -0.9 -0.4 -0.4 -0.6 -0.5 -0.1 0.2 -0.5 0.1 -1.6 -0.0 1.0
Forced expiratory volume in 1-second (FEV1) 0.7 2.5 7.6 -2.3 -2.5 -1.1 -1.4 -1.0 0.1 -0.5 0.5 2.6 -2.6 -2.0 0.4 -1.4 -1.2 0.9 0.9 -1.8 -2.7 -0.5 -0.3 1.6
Pulse rate 0.8 1.4 4.4 -0.2 0.9 1.7 0.6 0.7 -0.3 2.0 2.1 1.3 1.1 0.7 0.8 0.5 -0.5 1.2 1.5 0.4 1.1 0.4 2.0 -1.3
Happiness 0.8 1.0 4.4 2.1 1.5 0.7 1.3 0.7 0.2 1.1 -0.3 -1.0 0.8 1.7 0.2 -0.8 -0.7 -0.2 -0.4 1.7 1.2 0.3 0.6 -0.3
Noisy workplace 0.9 1.1 3.5 0.1 1.0 0.4 0.4 1.2 0.3 0.4 1.7 0.8 1.1 1.0 1.6 1.6 0.7 0.4 0.9 0.9 0.2 1.9 1.7 -1.1
Qualifications: A levels/AS levels or equivalent 1.2 2.7 7.9 -0.8 -1.5 -1.3 -1.3 -2.8 2.3 -2.0 -1.4 -0.7 -2.0 -1.9 -1.3 1.6 2.2 -0.5 -0.9 -2.0 -1.5 -1.6 -2.1 0.4
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 7.4 -1.4 0.2 -2.7 -1.6 0.9 0.7 -0.9 -0.7 0.5 -0.6 -1.0 -0.3 1.4 1.9 0.8 -0.3 -0.6 -0.9 0.7 -2.0 -0.5
Mouth/teeth dental problems: Dentures 1.6 2.7 13.0 -0.6 0.3 -1.8 -0.7 1.1 -3.6 -1.0 -2.1 -1.0 -1.9 -1.4 -2.5 -1.0 -0.2 -1.1 -1.1 -1.4 -0.5 -2.6 -2.5 1.4
Asthma 0.3 0.6 2.8 -0.3 0.4 -0.1 -0.9 -1.7 -0.1 0.5 0.8 0.8 -1.2 -0.2 -0.4 0.5 0.6 0.8 0.6 -0.2 -0.8 -0.7 -0.4 -1.4
Medication: Ibuprofen (e.g. Nurofen) 2.0 2.5 9.4 0.7 1.5 1.6 1.3 0.7 -0.4 2.0 2.0 1.2 1.0 0.8 2.7 -0.8 -1.3 3.1 2.2 0.9 0.6 1.9 1.9 -1.2
Medication: Cholesterol lowering 0.8 1.3 3.8 -1.0 -0.3 -1.6 -1.0 -0.7 0.0 -1.2 -1.1 0.1 -1.6 -1.2 -0.5 0.6 1.5 -1.5 -0.6 -0.9 -1.9 -1.0 -1.3 -1.2
Depression (self-reported) 1.6 1.9 7.3 0.3 1.2 1.3 -0.1 0.5 0.9 2.7 1.6 0.7 1.8 2.4 1.0 0.7 0.2 0.0 0.4 2.2 2.0 0.8 1.4 -1.6
Medication: Lansoprazole 1.3 1.5 5.6 0.4 0.7 1.0 0.9 1.9 -0.8 1.5 1.9 0.7 1.1 0.7 1.8 -0.2 -0.9 1.4 0.9 0.5 1.1 1.3 2.4 -0.7
Prospective memory result 0.8 0.9 4.5 0.4 0.7 1.2 0.8 1.2 -0.2 -0.3 -0.1 -1.5 2.1 1.1 0.1 1.2 0.6 -0.7 -0.7 0.8 1.7 0.5 0.8 0.4
Lung cancer (father) 1.0 1.2 10.3 0.6 0.4 -0.4 0.6 1.6 -3.2 -0.5 -0.7 -1.4 0.5 1.0 -0.6 0.5 0.5 -0.2 -1.4 0.9 1.5 -0.8 -0.6 0.7
Illnesses of mother 0.3 0.4 2.7 -0.1 -0.4 -0.2 0.0 0.9 -0.0 -0.7 -0.2 0.1 0.7 -1.0 0.3 -0.2 -0.1 1.6 -0.1 -0.7 -0.0 1.0 -0.1 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 9.0 -2.1 -2.1 -0.9 -1.3 -1.5 0.8 0.1 0.8 3.0 -2.4 -1.8 0.4 -1.8 -1.8 1.5 1.5 -1.7 -2.4 -0.3 -0.1 1.5
Pulse wave Arterial Stiffness index 0.8 1.0 4.4 0.5 0.4 0.4 0.9 0.2 -0.6 -0.6 1.4 0.7 -0.1 0.1 1.2 1.2 0.6 0.2 1.3 -0.1 -0.9 2.1 1.4 -1.8
Impedance of arm (left) 0.3 1.3 5.3 0.9 -1.3 -0.6 0.0 -0.5 0.6 0.9 1.3 1.3 -0.5 1.3 2.3 0.1 0.0 0.7 0.3 1.8 -0.7 1.0 1.7 -1.9
Arm fat mass (right) 0.6 2.6 9.7 -0.2 1.2 1.1 1.6 2.6 -2.1 2.1 1.8 1.1 0.5 0.8 1.7 -1.1 -2.0 2.2 3.1 0.7 0.7 0.8 1.8 -1.2
Trunk predicted mass 0.3 1.8 4.8 0.0 1.4 2.0 1.9 -0.5 -1.5 -0.3 0.4 0.1 0.4 -1.7 0.6 -1.6 -2.2 1.8 1.9 -2.0 0.3 0.9 1.1 1.7
Standing height 0.7 7.3 24.6 1.3 0.8 3.4 3.0 -2.0 0.3 1.2 3.3 2.6 0.3 -1.1 3.8 -1.8 -3.2 5.0 4.5 -1.2 -0.1 3.5 4.2 0.1
Length of working week for main job 0.4 0.4 1.4 -0.4 0.0 -0.7 0.1 -1.1 0.6 -0.8 -0.9 -0.4 -0.6 -1.2 -0.0 0.4 0.7 -0.5 -0.4 -1.0 -0.9 0.2 -0.3 -0.1
Exposure to tobacco smoke at home 0.3 0.3 1.8 -0.9 -0.2 0.4 -0.1 0.7 -0.4 0.6 0.5 0.9 -0.3 -0.3 -1.3 -0.3 -0.2 0.2 0.5 -0.6 -0.1 -0.8 0.1 0.5
Breastfed as a baby 0.5 0.6 2.9 -0.5 -0.6 -1.7 -0.5 1.4 0.7 -1.0 -0.5 -0.2 0.5 -1.1 -0.2 0.7 0.6 0.4 -0.3 -1.1 -0.0 0.9 -0.4 -0.1
Tense / ‘highly strung’ 0.3 0.5 2.5 -0.8 -0.8 -0.0 -1.4 0.1 0.6 0.1 0.1 0.7 -0.2 0.1 1.6 0.4 0.7 0.7 -0.9 0.6 -0.3 0.5 0.1 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 3.2 4.9 12.2 1.8 1.9 1.5 1.4 -0.0 1.5 2.7 2.3 -0.4 2.8 3.5 1.9 2.7 1.8 0.5 0.8 3.3 2.9 2.4 2.2 -3.5
Hair/balding pattern: Pattern 4 0.2 0.5 1.9 1.2 -0.8 -0.0 0.8 -0.2 -0.2 -0.3 0.1 -0.5 0.6 0.1 1.4 -0.5 -0.7 1.4 0.1 0.5 0.9 1.3 0.7 0.5
Birth weight of first child 0.3 0.5 2.7 0.7 1.0 0.8 0.3 -1.7 1.5 -0.6 -0.4 -0.3 0.1 -0.5 -0.2 0.3 0.5 0.3 0.6 -0.5 -0.4 1.1 -0.2 -0.3
Peak expiratory flow (PEF) 1.1 2.5 8.8 -2.6 -2.5 -0.5 -2.0 -0.2 -0.2 0.5 1.2 3.0 -2.8 -1.0 0.9 -1.4 -1.3 0.3 0.4 -0.7 -2.6 -1.3 0.2 0.9
Pulse wave reflection index 0.6 0.8 4.0 -0.9 -0.1 -0.3 -0.9 -0.1 -1.3 -2.0 -0.4 -0.1 -0.9 -0.4 -0.3 0.5 0.7 -1.8 -0.9 -0.3 -1.4 -0.2 -0.9 -0.1
Ever highly irritable/argumentative for 2 days 1.5 1.8 5.2 -0.5 -0.1 0.5 0.9 1.9 -1.1 2.1 1.9 1.9 -0.4 -0.5 -0.1 -1.3 -2.0 2.3 1.8 -1.0 1.0 0.3 1.8 0.1
Loud music exposure frequency 1.9 2.0 8.0 -0.3 -0.5 -0.1 -1.9 2.8 -1.1 2.2 1.9 2.7 0.0 2.2 0.1 0.5 0.3 0.4 0.7 2.1 -0.2 -0.6 0.7 -1.4
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 1.8 -1.0 -0.2 -0.6 -0.5 0.0 1.4 -0.2 0.4 0.7 -0.8 -1.0 -0.7 1.3 1.2 -0.6 0.8 -1.3 -0.8 -0.7 -0.2 -0.6
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.2 -1.1 -0.0 -0.4 -1.0 -0.3 0.5 0.7 0.1 0.4 -0.2 0.3 0.4 -0.1 -0.0 -0.3 -0.9 0.7 0.1 -0.9 -0.2 0.6
Blood clot in the leg (DVT) 3.4 4.5 16.7 -0.3 -0.0 -0.3 -3.9 -1.9 1.8 -0.5 -0.9 0.5 -1.8 1.0 -1.1 3.2 4.1 -3.2 -2.5 1.3 -2.7 -1.2 -2.5 -2.2
Medication: Paracetamol 0.7 1.1 5.2 0.5 1.3 0.9 0.8 1.2 -1.4 0.6 1.6 1.0 0.4 0.2 1.0 0.4 -0.3 1.1 2.3 0.0 -0.1 1.6 1.6 -0.2
Headache pain in last month 0.4 0.7 7.6 0.2 0.8 -0.3 0.0 1.5 -2.8 0.2 -0.3 -0.1 -0.8 0.4 -0.4 -0.5 -0.3 -0.5 -0.3 0.4 -0.0 -0.5 -0.2 0.9
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 4.6 1.2 0.4 1.3 0.9 0.2 1.2 1.3 1.7 1.0 1.1 1.2 1.1 -0.8 -1.7 2.1 1.5 1.0 1.4 1.9 1.6 0.6
Glaucoma (self-reported) 1.5 1.7 4.0 1.7 2.0 0.7 1.1 0.0 1.6 -0.4 -0.4 -2.0 1.6 1.5 -0.0 2.0 1.9 -0.6 -0.5 1.5 1.4 1.4 -0.1 -1.3
Gout (self-reported) 0.4 0.5 3.2 -0.1 0.6 0.4 0.6 1.8 -0.4 -0.3 -0.6 -0.8 1.4 -0.5 -0.5 0.2 0.2 -0.1 -0.6 -0.6 0.6 0.1 0.1 1.2
Hypothyroidism/myxoedema (self-reported) 1.1 2.2 10.1 0.6 0.2 -1.1 1.0 -1.2 -0.3 -1.1 -1.6 -1.7 -0.1 -1.8 -1.5 -2.4 -2.4 0.4 -1.0 -2.0 1.0 -0.9 -0.9 3.2
Medication: Amlodipine 2.0 2.8 6.2 -1.8 -1.2 -1.5 -1.3 1.0 -1.3 -2.5 -1.9 -1.0 -1.4 -1.8 -2.3 0.2 0.7 -2.3 -2.2 -1.9 -1.5 -2.1 -1.9 1.5
Medication: Ventolin 100micrograms inhaler 0.8 1.1 3.1 -1.1 -0.4 0.2 -0.5 -1.2 -0.4 0.3 1.6 1.8 -0.8 -0.5 1.3 0.6 0.4 1.4 1.4 -0.3 -1.5 0.8 0.8 -1.7
Birth weight 0.3 0.6 2.1 -1.2 0.8 0.1 -1.2 0.7 0.7 0.2 0.8 1.5 -0.3 -0.9 -0.7 0.5 0.2 0.0 1.0 -1.3 -0.8 0.1 -0.2 -0.3
Chronic bronchitis/emphysema (mother) 0.8 0.9 3.0 1.0 1.2 0.2 1.7 0.2 -0.8 0.2 -0.7 -1.3 0.7 0.8 0.9 -1.0 -1.0 0.3 -1.0 0.9 1.7 0.6 1.2 0.7
High blood pressure (siblings) 1.6 2.4 6.7 0.2 1.5 0.8 -1.4 0.2 -1.8 1.1 -0.7 -1.2 -0.1 1.7 -1.9 1.6 1.8 -2.0 -2.3 1.7 1.2 -2.6 -1.5 -1.9
Forced vital capacity (FVC), Best measure 0.7 2.4 6.3 -1.3 -1.5 -1.0 -0.7 -2.2 0.2 -0.5 0.6 2.5 -2.2 -2.1 0.9 -1.5 -1.6 2.2 1.7 -2.0 -2.2 0.4 0.1 1.5
Body fat percentage 1.0 4.1 12.5 0.1 1.3 0.7 1.2 2.9 -1.3 3.4 2.6 1.9 0.2 2.0 2.5 -0.7 -1.5 2.5 3.5 2.1 0.8 0.7 2.1 -2.8
Leg fat percentage (right) 0.7 2.4 6.9 0.3 1.8 0.6 1.3 2.6 -1.0 2.6 1.7 0.5 0.9 2.0 1.4 0.1 -0.6 1.6 2.3 1.9 1.3 0.3 1.3 -2.3
Arm fat-free mass (right) 0.5 2.7 8.7 0.1 1.7 2.8 2.0 0.4 -1.3 1.1 1.8 1.2 0.3 -0.9 1.4 -1.2 -2.2 2.8 2.9 -1.4 0.8 1.3 2.0 0.7
Exposure to tobacco smoke outside home 0.7 1.0 2.7 0.0 -1.2 0.7 0.6 1.1 0.7 1.6 1.0 0.4 0.8 1.2 0.5 -1.0 -1.6 -0.2 0.5 1.0 1.6 -0.0 1.2 1.1
Comparative body size at age 10 0.3 0.8 2.8 0.6 1.0 0.4 0.7 0.4 0.5 -1.7 -1.0 -1.5 1.6 -0.1 -0.9 1.2 1.0 -0.3 -0.5 -0.5 0.7 1.4 -0.4 0.4
Number of full brothers 1.3 1.7 5.0 0.3 0.2 1.1 0.8 1.6 -0.9 2.1 2.0 1.4 0.1 1.3 2.2 -0.7 -1.3 1.6 1.1 1.4 1.1 0.6 1.7 -0.5
Worry too long after embarrassment 1.0 1.7 6.9 -1.9 -2.2 -1.5 -0.7 -1.2 0.4 -1.3 0.0 1.2 -1.2 -1.7 -0.1 -1.3 -1.2 -1.2 0.1 -1.8 -2.6 -0.2 0.1 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.7 2.1 7.2 0.7 1.9 1.7 0.8 -0.7 1.3 1.6 1.4 -0.3 1.7 2.7 1.3 1.5 1.0 -0.6 -0.3 2.5 1.4 1.0 1.6 -1.8
Wheeze or whistling in the chest in last year 0.7 1.2 3.6 -0.5 0.7 1.2 -0.3 -0.0 -1.9 1.9 1.8 1.8 -1.1 0.9 0.9 -0.1 -0.5 1.2 1.6 0.9 -0.4 -0.7 1.1 -0.9
Number of children fathered 0.3 0.4 1.6 1.3 0.2 0.2 0.3 0.4 0.2 0.4 -0.5 -0.8 0.3 1.1 -0.4 0.4 0.6 -0.9 -0.2 1.1 0.5 -0.2 -0.5 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 1.8 -0.5 0.3 0.1 0.4 -0.5 -0.6 -0.5 -0.1 0.4 -0.5 -1.1 -0.0 0.0 0.1 0.3 0.7 -1.3 -0.7 -0.0 0.2 -0.1
Age at first live birth 0.7 1.3 4.0 0.8 1.0 -1.1 -0.6 -2.0 1.1 -1.7 -1.9 -1.4 -0.6 -0.3 -0.8 0.0 0.6 -0.3 -1.7 -0.1 -0.5 -1.2 -1.9 0.4
Pulse wave peak to peak time 0.6 0.7 2.7 -0.3 -0.3 -0.0 -0.5 -0.1 0.7 1.2 -0.8 -0.3 0.2 0.1 -0.7 -1.4 -0.9 0.4 -0.6 0.2 1.0 -1.7 -0.8 1.6
Health satisfaction 1.3 1.6 6.0 0.2 -1.9 -1.6 -0.0 0.4 -0.4 0.2 -1.7 -0.6 -1.2 -1.5 -2.4 -1.4 -1.1 0.5 0.3 -1.5 0.3 -1.6 -2.0 1.7
Shortness of breath walking on level ground 1.1 1.3 3.9 1.3 0.7 1.0 1.4 2.0 0.4 0.9 0.5 -0.6 1.5 0.9 1.0 0.7 0.1 1.2 1.5 0.8 1.6 1.9 1.1 -0.8
Qualifications: College or University degree 0.7 2.2 13.7 0.3 -1.1 -1.2 -0.0 -3.7 1.3 -2.3 -1.8 -1.4 -0.7 -1.0 -1.2 -0.4 0.2 -1.1 -1.4 -0.9 -2.3 -1.1 -1.6 1.1
Eye problems/disorders: None of the above 1.3 1.4 4.9 -1.9 -1.2 0.5 -0.5 0.6 0.6 0.7 0.9 2.2 -0.5 -1.3 0.2 -1.6 -1.9 1.4 2.1 -1.4 -1.0 -0.1 0.2 0.7
Mouth/teeth dental problems: Loose teeth 0.8 1.0 2.3 -1.2 -0.4 -1.4 -0.6 0.4 0.1 -1.3 -1.5 -1.1 -0.3 -0.7 -0.8 0.0 0.4 -1.4 -1.5 -0.6 -0.2 -1.0 -1.4 1.3
Emphysema/chronic bronchitis 0.4 0.5 2.3 -1.2 0.2 0.2 -0.1 1.5 0.1 1.1 1.1 0.8 -0.1 0.6 0.4 -0.5 -0.9 -0.2 0.0 0.5 0.3 -0.4 0.8 -0.1
Medication for pain relief, constipation, heartburn 0.9 1.5 5.9 0.2 -1.0 -0.1 -0.5 -1.5 1.2 -1.5 -1.5 -1.6 -0.4 -0.1 -1.4 0.9 1.2 -1.9 -2.4 -0.2 0.4 -1.5 -1.4 0.8
Neck or shoulder pain in last month 0.8 1.2 6.1 0.0 0.8 0.8 0.4 0.0 -0.3 1.6 1.3 1.4 0.1 -0.0 0.8 0.2 -0.4 2.3 2.5 -0.0 0.7 1.2 0.9 -1.5
Medication: Blood pressure 1.4 2.5 8.2 -1.6 -0.8 -1.6 -0.8 1.1 -2.1 -1.4 -1.9 -1.0 -1.4 -1.5 -2.0 -0.7 0.3 -2.3 -1.3 -1.4 -1.6 -2.9 -2.0 0.7
Angina (self-reported) 1.1 1.5 5.6 -0.2 -0.3 1.8 -0.2 1.4 0.1 2.4 2.3 1.9 1.0 0.8 0.7 -0.1 -0.9 0.5 2.1 0.4 0.2 0.1 1.9 -0.5
Migraine (self-reported) 1.1 1.4 7.2 0.5 1.7 0.9 1.0 2.7 -0.8 0.8 -0.3 -1.2 1.5 0.9 -1.3 -0.4 -0.6 -0.5 -1.0 0.5 2.3 -0.8 0.2 1.3
Medication: Ibuprofen 2.2 2.6 9.7 0.3 1.2 1.3 0.6 0.5 -0.3 2.0 2.2 1.5 1.1 1.2 3.1 -0.1 -0.5 2.8 1.9 1.5 0.2 2.2 2.0 -2.2
Medication: Allopurinol 0.8 1.0 5.2 0.5 0.6 -0.4 1.5 2.0 -2.3 -0.6 -1.1 -1.5 1.4 -0.2 -0.8 -0.2 -0.1 0.1 -0.7 -0.4 1.1 0.0 0.0 0.9
Medication: Omeprazole 1.0 1.2 4.0 -0.9 -0.8 0.7 0.3 1.6 0.4 2.0 1.7 1.6 -0.1 0.8 1.4 -1.0 -1.6 0.6 1.5 0.7 0.2 0.5 1.3 -0.7
Medication: Seretide 50 evohaler 0.7 0.8 4.6 -0.5 -2.1 -0.6 -0.1 -0.7 0.1 -0.5 -0.7 -0.2 -1.2 -1.4 0.5 -1.4 -1.1 1.0 -0.6 -1.0 0.1 -0.3 -0.5 1.1
Mean time to correctly identify matches 0.2 0.4 1.5 0.0 -1.2 -0.3 1.0 0.6 0.3 -0.6 -0.3 -0.6 0.8 0.2 0.4 -0.9 -1.0 0.3 0.4 0.3 0.3 0.4 0.5 1.0
Heart disease (mother) 0.5 0.6 7.3 0.6 0.1 0.0 1.0 -2.7 0.1 0.3 0.7 0.0 -0.4 0.3 0.4 0.5 0.1 0.5 0.9 0.1 0.1 0.5 0.6 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 3.4 0.8 0.4 0.8 0.9 1.5 -0.3 -1.0 -0.9 -1.9 1.6 -0.2 0.1 1.1 1.2 -0.1 -1.0 -0.2 0.8 0.4 -0.3 -0.2
Whole body fat mass 0.9 3.7 14.2 0.3 1.5 1.3 2.0 2.4 -1.8 2.8 2.3 1.5 0.3 1.2 2.3 -1.3 -2.2 3.0 3.8 1.2 0.9 0.9 2.2 -1.6
Leg fat mass (right) 0.8 3.1 8.9 0.4 2.1 1.3 2.0 2.8 -1.8 2.5 1.8 0.6 1.0 1.5 1.8 -1.1 -1.9 2.5 3.0 1.3 1.4 0.7 1.8 -1.3
Arm predicted mass (right) 0.4 2.2 7.0 0.2 1.4 2.5 2.1 -0.0 -1.4 0.7 1.1 0.8 0.0 -1.3 1.1 -1.4 -2.2 2.5 2.6 -1.6 0.6 1.1 1.6 1.0
Pulse rate, automated reading 0.6 2.1 6.2 0.4 0.8 1.7 0.5 2.0 -0.1 2.1 2.5 1.3 1.0 1.0 0.6 2.1 0.8 1.0 1.9 0.4 1.2 0.8 2.1 -2.2
Alcohol intake frequency. 2.2 5.0 14.0 1.8 2.5 2.6 1.1 3.5 0.3 1.8 1.6 -1.0 2.8 3.7 1.5 2.3 1.5 -0.2 -0.7 3.5 2.6 2.1 2.6 -2.4
Comparative height size at age 10 1.0 5.5 20.3 -0.1 0.5 2.1 2.4 0.9 0.2 1.0 2.7 2.3 1.0 -0.8 3.5 -1.3 -2.3 4.5 4.4 -0.9 -0.2 3.9 3.4 -1.4
Number of full sisters 1.0 1.2 7.5 -0.2 -0.0 0.5 0.2 1.2 -0.8 1.1 1.4 1.5 0.9 -0.5 0.7 0.2 -0.2 2.7 2.2 -0.4 0.3 1.7 0.8 -0.6
Suffer from ‘nerves’ 0.8 1.3 4.7 0.3 0.0 1.8 0.6 0.4 -0.3 1.7 1.8 1.0 0.9 0.5 1.9 0.0 -0.6 0.6 0.8 0.6 1.2 1.3 2.2 -1.1
Overall health rating 0.6 1.3 4.5 -0.3 -0.7 -0.7 0.8 0.7 -1.1 2.0 1.0 1.1 -0.8 -0.1 0.7 -1.8 -1.9 1.9 2.1 0.1 0.4 -0.1 1.0 -0.5
Chest pain or discomfort 0.3 0.4 1.8 0.1 -0.1 0.5 0.2 -0.5 0.0 1.3 0.9 1.1 -0.1 -0.0 0.2 -0.5 -1.0 0.9 1.1 -0.2 0.5 -0.1 0.8 0.1
Had major operations 1.3 1.6 7.2 -1.8 -1.0 -0.0 -1.4 1.4 -0.7 1.4 2.4 2.7 -1.2 0.3 1.2 0.5 -0.0 0.6 1.1 0.2 -0.9 -0.5 1.4 -1.2
Age at last live birth 0.5 0.7 4.6 0.2 0.7 -0.5 -0.7 -1.4 -0.6 0.1 -0.8 -0.5 -1.3 -0.1 -1.0 -0.6 -0.2 0.0 -0.8 -0.0 -0.1 -2.1 -1.2 0.3
Family relationship satisfaction 0.2 0.3 1.0 0.9 0.7 -0.1 0.5 0.3 0.9 1.0 0.2 -0.1 -0.1 0.8 0.0 -0.5 -0.5 -0.3 0.1 0.9 0.1 0.2 0.1 -0.5
Leg pain on walking 1.0 1.3 3.9 -1.3 -1.7 -0.9 -1.1 2.0 -1.1 0.4 0.3 1.4 -1.1 -1.6 -0.9 -0.2 -0.5 0.9 0.8 -1.9 -0.0 -0.9 -0.3 1.3
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 4.3 -2.1 -1.7 -0.8 0.1 0.4 -1.1 -0.4 0.6 1.1 -0.4 -1.8 0.3 -1.6 -1.8 0.8 0.6 -1.9 0.2 0.6 0.4 1.4
Commuting to job workplace: Car/motor vehicle 0.6 0.7 4.4 -0.8 0.1 -0.4 -0.7 2.1 -2.0 0.8 0.4 1.2 -0.7 -0.3 0.2 -0.2 -0.1 0.7 0.7 -0.3 -0.1 -0.4 0.1 -0.4
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 4.1 -0.8 -2.0 -0.1 -0.8 -1.5 1.0 -1.5 -0.7 0.6 -0.8 -1.8 -0.9 -0.4 -0.2 -0.1 0.0 -1.9 -1.6 -0.7 -0.6 1.1
Medication: Aspirin 0.7 0.9 3.8 -1.2 -0.5 -1.8 0.3 0.5 -0.7 -0.9 -0.8 -0.1 -0.7 -1.9 -0.7 -0.6 -0.2 0.4 0.5 -1.9 -1.1 -0.0 -0.6 -0.3
Supplements: Vitamin C 0.3 0.4 1.4 0.4 -0.6 -0.3 0.6 1.2 -0.6 0.5 0.3 -0.0 0.5 -0.4 0.1 -0.2 -0.6 0.7 1.1 -0.4 1.0 0.3 0.7 0.4
Knee pain experienced in last month 0.7 1.2 3.9 -0.7 -0.5 -1.1 0.8 0.0 -1.2 -0.7 -0.2 0.4 -1.1 -1.6 1.1 -1.9 -2.0 1.3 0.9 -1.2 -0.2 0.7 -0.0 1.6
Hypertension (Self-reported) 0.4 1.2 6.6 -1.9 -0.6 0.5 -0.6 2.6 -1.6 0.0 0.0 -0.4 0.0 0.2 -1.0 0.9 0.9 -1.8 -1.3 -0.1 0.0 -1.8 -0.1 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.0 -0.6 -1.0 -0.7 0.3 0.6 1.0 0.8 0.1 0.1 -0.0 0.4 0.1 -0.7 -0.9 -0.8 0.2 0.3 -0.2 0.2 0.5 0.3
Illnesses of father: Heart disease 0.9 1.2 8.3 0.3 -0.4 1.3 0.6 -2.9 0.3 0.3 1.2 0.5 0.5 -0.7 1.3 0.9 0.1 1.6 1.1 -0.7 0.9 1.7 1.0 -1.0
Illnesses of siblings: Diabetes 0.2 0.2 1.3 0.5 0.3 -0.4 0.2 -0.2 -0.8 0.2 0.6 0.4 0.0 -0.0 -0.1 0.8 0.6 0.6 0.4 -0.3 0.1 0.6 0.4 -1.1
Smoking status: Previous 0.4 0.6 2.2 0.7 -0.0 -0.6 1.4 -0.4 1.5 0.6 -0.0 -0.3 0.3 -0.1 0.1 -0.8 -1.1 1.1 1.0 -0.2 1.3 1.0 0.2 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 3.6 0.4 0.4 0.9 1.3 -1.2 0.9 1.1 0.9 0.6 0.5 -0.2 0.4 -1.4 -1.8 1.9 1.5 -0.4 0.8 0.5 1.3 1.2
Whole body fat-free mass 0.4 2.3 6.7 0.1 1.3 2.0 2.1 -0.1 -1.8 0.2 0.8 0.5 0.2 -1.5 1.1 -1.9 -2.6 2.3 2.6 -1.7 0.3 1.2 1.4 1.3
Leg fat-free mass (right) 0.5 2.6 9.7 0.1 1.0 1.7 2.1 0.4 -1.9 0.6 1.0 0.9 -0.1 -1.2 1.6 -2.1 -2.7 2.6 3.1 -1.2 0.0 1.5 1.6 0.7
Arm fat percentage (left) 0.6 2.4 9.5 -0.2 0.8 0.2 1.2 3.1 -2.0 2.3 1.6 1.1 0.0 1.4 1.9 -0.9 -1.5 1.7 2.5 1.5 0.5 0.4 1.5 -2.0
Average weekly red wine intake 1.2 1.8 7.2 0.8 0.1 -1.4 -1.1 -1.0 -1.3 -2.7 -1.9 -1.2 -1.0 -1.2 -0.5 1.0 1.6 -0.9 -2.3 -1.0 -1.5 -0.5 -1.5 -0.3
Handedness (chirality/laterality): Left-handed 0.4 0.5 3.8 0.9 0.4 2.0 0.3 0.8 -0.9 0.4 0.3 -0.3 0.7 0.6 -0.5 0.3 0.1 -0.6 0.2 0.3 0.2 -1.1 0.2 0.8
Mood swings 0.9 1.5 5.7 0.3 1.2 0.2 -0.5 1.4 -0.5 2.4 1.1 0.7 0.3 1.9 2.2 -1.4 -1.2 0.4 1.1 2.4 0.0 0.6 0.7 -1.4
Loneliness, isolation 0.9 1.2 4.2 -0.5 -0.5 -1.1 -0.2 -0.5 -1.9 0.3 0.4 1.4 -2.1 -0.3 1.9 -1.1 -0.8 1.8 1.2 0.2 -1.2 0.7 0.5 -0.7
Long-standing illness, disability or infirmity 0.5 0.8 3.3 0.4 0.6 -1.8 0.2 -1.2 -1.8 -0.0 -1.3 -1.4 -0.6 -0.1 -0.1 -0.1 0.6 -0.1 -1.2 0.4 0.8 -0.8 -0.7 -0.8
Ever had bowel cancer screening 1.0 1.1 5.6 -0.1 0.2 0.4 -0.2 -1.8 0.9 0.4 1.1 1.0 0.1 -0.1 0.0 1.9 1.7 -0.2 1.5 -0.5 -1.1 0.8 0.7 -2.4
Diabetes diagnosed by doctor 0.7 1.1 5.0 -1.7 -1.6 -0.4 -1.5 -0.0 -0.9 0.3 0.3 0.7 -1.9 -0.9 -0.5 -0.6 -0.6 -1.4 -0.8 -1.1 -0.6 -2.2 -0.5 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 2.3 0.0 0.1 -0.3 -0.7 -0.4 0.8 -0.7 -0.9 -0.8 0.3 0.2 -1.3 0.8 1.1 -1.5 -1.4 0.2 0.2 -1.1 -1.2 0.6
Friendships satisfaction 0.2 0.3 3.5 0.7 0.1 -0.2 0.0 1.9 -0.6 0.1 -0.2 0.2 -0.7 -0.3 -0.4 -0.4 -0.3 0.0 0.3 -0.2 -0.0 0.1 -0.2 -0.2
Qualifications: nursing, teaching 0.4 0.6 2.4 -0.1 0.5 0.1 -0.2 -0.5 -0.9 -1.2 -0.8 -0.9 -0.4 -0.4 -1.0 0.3 0.5 -1.6 -0.7 -0.5 -1.2 -1.3 -0.7 0.1
Commuting to job workplace: Walk 0.6 0.7 2.5 0.0 0.1 1.4 -0.3 -0.4 0.9 0.8 1.5 0.8 -0.1 0.6 -0.1 1.3 0.7 -0.6 -0.4 0.2 0.2 -0.2 1.2 -1.6
Eye problems/disorders: Cataract 0.3 0.4 1.3 0.6 0.9 0.1 -0.5 0.2 -0.0 0.6 0.5 -0.0 0.2 1.1 0.3 1.1 1.0 -0.2 -0.4 1.0 0.6 0.2 0.5 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 5.1 1.3 1.0 0.4 0.4 0.6 0.2 0.4 -0.6 -1.2 1.9 1.5 -0.8 0.1 0.3 -1.9 -2.3 1.3 2.1 -0.5 0.0 0.5
Medication for cholesterol 1.4 2.2 9.4 2.7 2.0 0.1 3.1 -0.4 -1.2 -0.1 -0.7 -1.6 0.9 0.6 0.9 -2.3 -2.3 0.4 1.1 0.7 0.8 1.1 1.0 1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.8 3.3 7.5 -0.6 -1.8 -1.7 -1.3 0.7 -1.1 -2.1 -2.5 -1.0 -2.0 -1.5 -2.6 -0.5 0.4 -2.1 -2.2 -1.3 -1.8 -2.7 -2.6 2.4
Back pain experienced in last month 0.7 1.1 4.5 -0.1 0.2 0.4 0.0 -0.8 -0.6 1.7 1.5 1.6 -0.5 -0.0 0.8 -0.7 -1.2 2.1 2.0 0.0 0.4 0.9 0.9 -0.7
Mineral and other dietary supplements 1.2 1.6 8.5 -0.9 -0.0 -0.3 -1.3 -0.5 -0.7 -0.6 -0.5 -0.3 -1.1 0.6 -0.8 1.3 1.9 -2.9 -2.0 0.5 -1.6 -1.9 -0.8 -1.2
Breast cancer (self-reported) 2.4 2.9 7.1 -2.2 -2.2 -1.5 -2.6 -1.7 0.9 -0.8 -0.4 1.8 -2.2 -2.6 -1.5 -1.1 -0.8 -1.1 0.1 -2.7 -2.2 -1.7 -1.4 1.0
Asthma (self-reported) 0.3 0.5 2.3 -0.1 0.5 0.2 -0.5 -1.5 -0.1 0.6 1.0 0.8 -0.9 -0.1 -0.1 0.5 0.4 1.3 0.9 -0.2 -0.5 -0.2 -0.0 -1.3
Osteoporosis (self-reported) 0.1 0.2 0.6 -0.2 -0.0 -0.1 -0.4 -0.5 -0.5 -0.5 0.1 0.2 -0.8 -0.3 -0.6 0.5 0.6 -0.3 -0.0 -0.4 -0.4 -0.4 -0.5 0.2
Osteoarthritis (self-reported) 1.2 1.5 5.0 -0.5 -1.6 -0.9 1.2 1.7 -1.4 1.0 0.9 0.8 0.3 -0.8 1.0 -1.7 -2.2 1.6 2.0 -0.9 0.2 0.9 1.1 0.9
Medication: Aspirin 0.4 0.6 2.7 -1.2 -0.3 -1.6 -0.0 0.9 -0.8 -0.4 -0.7 -0.1 -0.5 -1.3 -0.7 -0.5 -0.2 0.1 0.2 -1.3 -0.8 -0.4 -0.7 -0.3
Medication: Gliclazide 1.1 1.2 3.9 -0.5 -0.6 1.5 0.3 -0.5 -0.8 1.7 1.6 1.3 -1.0 -0.4 1.3 0.0 -0.5 1.9 2.0 -0.4 0.1 0.4 1.2 -1.5
Illnesses of father: None of the above (group 1) 0.9 1.1 7.5 0.6 0.2 -0.7 0.9 1.6 -0.1 -1.3 -1.0 -0.5 -0.6 -0.4 -0.9 -1.9 -1.7 0.3 0.1 -0.6 -0.7 -0.3 -0.4 2.7
Smoking status: Current 1.6 2.5 12.8 -0.4 0.4 0.9 -0.9 3.6 -2.4 3.4 1.8 1.7 0.6 1.8 0.5 -0.9 -1.4 -0.8 0.1 1.7 1.3 -1.0 1.3 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.2 7.7 -2.4 -0.7 -2.1 -2.8 -2.0 1.7 -0.4 -0.0 1.7 -1.8 -0.9 -0.8 0.1 0.4 -1.1 -0.2 -0.8 -2.1 -1.5 -1.8 0.2
Whole body water mass 0.4 2.3 6.7 0.0 1.3 2.0 2.0 -0.1 -1.9 0.3 0.9 0.6 0.2 -1.4 1.1 -1.9 -2.5 2.4 2.6 -1.6 0.3 1.1 1.5 1.3
Leg predicted mass (right) 0.5 2.6 9.7 0.1 1.0 1.7 2.1 0.5 -1.8 0.6 1.0 0.9 -0.1 -1.2 1.5 -2.1 -2.8 2.6 3.1 -1.2 0.0 1.5 1.6 0.8
Arm fat mass (left) 0.6 2.5 9.3 -0.2 1.1 0.9 1.5 2.6 -2.2 2.1 1.7 1.2 0.1 0.7 1.6 -1.3 -2.1 2.2 3.1 0.7 0.6 0.5 1.6 -1.2
Number of self-reported non-cancer illnesses 0.5 0.9 3.2 -1.8 -1.5 -0.1 -0.9 1.3 -1.2 0.4 0.3 0.7 -0.8 -0.7 -1.0 -0.4 -0.7 -0.9 -0.6 -1.0 -0.2 -1.5 0.1 0.8
Average weekly champagne plus white wine intake 0.3 0.4 1.3 -0.2 0.6 -1.1 0.3 0.4 0.8 -0.4 -0.6 -0.3 0.6 -1.1 0.1 -0.8 -0.6 0.9 0.7 -0.9 0.3 0.7 -0.5 0.4
Miserableness 0.2 0.4 1.8 0.1 -0.5 0.7 0.7 1.0 1.0 0.7 0.4 0.1 0.2 -0.3 0.0 -0.3 -0.6 -0.1 1.3 -0.6 0.1 -0.0 0.5 1.2
Guilty feelings 1.2 1.8 6.3 -0.5 -0.7 -0.3 0.4 -2.4 0.7 0.3 1.7 1.7 -0.2 -0.6 2.5 0.5 0.2 1.8 1.6 -0.4 -0.7 2.3 1.9 -1.4
Wears glasses or contact lenses 0.8 0.9 6.0 0.4 1.3 -0.8 0.2 -2.5 0.1 -0.4 -1.1 -1.4 0.7 -0.2 -0.9 0.7 0.8 -0.9 -1.3 -0.4 0.8 -0.9 -0.6 -0.0
Ever taken oral contraceptive pill 0.4 0.4 1.5 -1.0 -1.2 -1.2 -0.6 -0.1 0.8 0.4 -0.2 0.5 -1.2 -0.0 -0.2 0.3 0.6 -0.8 -0.3 0.2 -0.3 -0.4 -0.6 -0.8
Hearing aid user 1.8 2.1 8.0 -2.8 -2.2 -1.2 -1.6 0.7 -0.7 0.3 0.8 2.3 -1.0 -2.2 0.4 -1.7 -1.5 0.7 0.8 -2.1 -1.3 -0.4 0.3 1.2
Mother’s age at death 0.3 0.4 2.5 0.4 -0.3 -1.6 -0.7 0.6 0.7 -0.0 -0.3 0.6 0.2 -0.1 0.2 -1.2 -0.9 0.2 0.9 0.1 -0.5 -0.0 -0.4 0.8
Financial situation satisfaction 1.9 2.3 6.9 2.1 2.0 1.6 1.6 1.1 0.5 2.5 1.1 -0.3 1.8 1.5 1.0 0.2 -0.2 1.8 1.2 1.5 2.6 1.3 1.3 -1.6
Tinnitus: Yes, now most or all of the time 0.8 0.9 4.0 -0.6 -0.0 -0.4 -0.4 -0.2 -0.5 -2.0 -0.8 -0.6 -0.1 -1.3 -0.0 1.7 1.9 -0.4 -0.7 -1.2 -1.4 0.4 -0.5 -0.3
Commuting to job workplace: Public transport 0.8 0.9 3.6 0.6 0.0 0.6 1.9 -0.2 1.2 -0.6 -0.1 -1.9 1.6 -0.1 0.6 1.0 0.3 0.3 -0.1 -0.4 1.2 1.6 0.9 -0.0
Eye problems/disorders: Glaucoma 1.2 1.4 4.0 1.8 1.7 0.9 1.2 0.3 0.5 -0.6 -0.4 -2.0 1.7 1.7 -0.3 1.1 0.9 -1.2 -0.9 1.7 1.1 1.0 0.0 -0.8
Medication: Blood pressure 0.6 1.2 6.6 -2.6 -1.5 0.6 -1.5 1.3 0.5 0.1 1.2 1.4 -0.3 -0.6 0.9 1.3 0.9 0.5 0.3 -0.6 -0.5 0.4 0.5 -1.7
Pain type(s) experienced in last month: Hip pain 1.5 1.9 7.3 -0.3 1.4 1.3 0.3 1.4 -0.3 2.3 2.7 1.6 0.6 1.5 1.2 0.6 -0.4 1.1 2.1 1.1 0.9 0.2 1.9 -1.6
Supplements: Fish oil (including cod liver oil) 1.5 2.0 12.2 0.4 -0.1 -0.7 1.6 -0.1 -0.3 0.2 -0.0 0.2 0.5 -1.1 1.2 -2.4 -2.6 3.5 1.8 -0.8 1.2 1.7 0.5 1.1
High cholesterol (Self-reported) 0.8 1.5 3.3 -1.1 -0.8 -1.1 -1.7 -0.2 -1.3 -0.1 -1.0 0.4 -1.7 -1.0 -1.6 1.0 1.7 -1.8 -0.9 -1.0 -0.8 -1.7 -1.7 -1.1
Medication: Bendroflumethiazide 0.6 0.9 3.6 -0.6 0.3 0.7 -0.2 0.3 -1.2 -0.5 -0.7 -1.5 1.1 0.0 -0.4 1.6 1.9 -1.3 -1.4 -0.1 0.4 -0.4 -0.8 -1.3
Medication: Paracetamol 0.9 1.4 4.7 0.8 1.1 1.1 1.1 1.7 -1.1 0.9 1.6 0.8 1.1 0.5 1.2 0.1 -0.7 1.4 2.2 0.3 0.2 1.9 1.9 -0.0
Medication: Lisinopril 1.3 1.7 6.0 -1.2 0.3 -1.1 -0.4 1.2 -1.8 -0.3 -1.4 -1.0 -0.6 -1.0 -2.2 -0.7 -0.2 -2.1 -1.2 -1.1 -0.2 -2.5 -1.8 1.1
Medication: Atorvastatin 1.4 1.8 5.1 -2.2 -0.8 -0.9 -2.2 0.2 0.8 -0.7 -0.7 0.9 -1.6 -1.2 -1.7 0.5 1.1 -1.6 -1.0 -1.1 -2.0 -1.6 -1.8 -0.4
Illnesses of father: High blood pressure 1.4 1.7 5.9 -0.9 -0.8 -0.4 -0.1 -0.2 -0.5 -1.5 -2.0 -1.7 0.0 -1.4 -1.5 -1.0 -0.3 -1.5 -2.4 -1.2 0.0 -2.2 -1.5 1.8
Alcohol drinker status: Never 1.1 1.4 4.1 0.6 1.3 0.9 -0.5 1.9 -0.8 1.6 0.4 -0.2 0.7 1.2 -0.2 1.8 1.8 -1.1 -1.2 1.1 1.4 -0.5 0.4 -2.0
Ever smoked 0.6 1.0 6.3 -0.2 -0.8 0.0 0.4 1.8 -0.4 1.7 0.8 0.8 -0.4 0.2 0.5 -2.2 -2.5 0.1 0.6 0.2 0.9 -0.5 0.4 0.1
Basal metabolic rate 0.5 2.5 8.6 0.1 1.5 2.0 2.2 0.4 -1.9 0.7 1.1 0.7 0.4 -1.0 1.4 -1.9 -2.6 2.7 2.9 -1.2 0.5 1.2 1.7 0.8
Leg fat percentage (left) 0.7 2.6 6.8 0.3 1.9 0.8 1.2 2.3 -0.4 2.5 1.9 0.7 0.8 2.1 1.7 0.4 -0.3 1.7 2.6 2.0 1.1 0.6 1.4 -2.5
Arm fat-free mass (left) 0.5 2.3 7.9 0.1 1.8 2.4 2.1 0.2 -1.1 0.7 1.4 0.7 0.6 -1.0 1.0 -1.2 -2.1 2.6 2.8 -1.4 0.8 1.2 1.8 0.8
Number of operations (self-reported) 1.3 2.0 7.0 -0.9 -1.3 0.6 -0.5 1.5 1.4 2.6 2.4 2.4 -0.6 0.7 0.7 -0.9 -1.8 1.2 2.1 0.5 0.3 0.3 1.6 -1.0
Average weekly beer plus cider intake 2.2 3.1 9.2 -3.0 -2.6 -1.9 -1.0 1.2 0.1 0.1 -1.3 0.7 -1.3 -2.0 -1.5 -2.8 -2.2 -0.2 -0.1 -1.7 -0.8 -2.1 -1.8 3.0
Irritability 0.3 0.6 2.3 0.2 0.7 -1.0 0.6 0.6 -1.5 -0.9 -0.9 -0.8 -0.4 -0.8 0.6 -0.8 -0.6 1.3 0.2 -0.7 0.2 -0.2 -0.3 0.6
Risk taking 0.1 0.2 0.8 0.2 0.6 -0.1 -0.5 0.3 0.6 -0.4 -0.0 0.2 -0.1 -0.2 -0.3 0.9 0.9 -0.1 -0.3 -0.3 -0.3 -0.2 -0.3 -0.6
Ever had prostate specific antigen (PSA) test 0.7 0.8 3.0 0.8 0.7 -0.3 -0.7 -0.8 -0.2 -0.7 -0.7 -0.5 -0.4 0.3 -1.1 1.4 1.7 -1.6 -1.2 0.2 -1.0 -0.4 -0.8 -1.1
Fractured/broken bones in last 5 years 2.4 3.1 13.6 -0.2 0.3 -1.1 2.2 -0.2 -2.4 -1.9 -2.1 -1.9 -0.1 -2.1 -1.9 -2.7 -2.5 0.2 -0.1 -2.2 0.5 -1.0 -0.8 3.7
Age started oral contraceptive pill 0.4 0.5 1.8 -0.8 -0.6 0.1 -0.3 1.3 0.3 -0.2 1.3 0.5 0.7 -0.1 0.9 1.1 0.3 -0.0 0.5 -0.5 0.1 0.9 0.8 -0.9
Diastolic blood pressure, automated reading 0.4 1.3 6.0 -0.5 0.7 -0.0 0.4 1.8 -2.4 -0.8 -1.2 -1.7 0.8 0.2 -1.1 1.0 1.4 -1.3 -1.7 0.3 0.4 -1.1 -0.7 -0.1
Ever depressed for a whole week 1.6 2.0 5.5 1.2 1.7 0.5 0.0 0.4 0.5 0.4 -0.2 -1.6 1.6 1.7 -1.2 2.3 2.0 -2.4 -2.3 1.2 2.0 -0.6 -0.1 -1.0
Unable to work because of sickness or disability 0.3 0.4 1.5 -0.7 0.4 0.5 -0.7 0.3 -0.4 0.4 0.8 0.7 -0.2 0.7 0.7 1.0 0.7 1.0 0.0 0.6 0.1 0.7 0.6 -1.2
Commuting to job workplace: Cycle 0.9 1.0 4.4 1.3 2.0 0.7 0.2 2.1 -0.0 -0.1 -0.7 -1.4 1.3 0.7 -0.2 1.0 1.3 0.1 -1.1 0.6 1.3 0.3 -0.3 -0.5
Myopia 0.8 1.2 5.1 0.3 -0.9 -0.7 0.9 -2.3 1.5 -2.2 -1.2 -1.0 -0.4 -1.4 1.0 0.3 0.6 0.9 -0.4 -1.1 -0.6 1.5 -0.5 -0.2
Vascular/heart problems diagnosed by doctor 0.5 1.5 5.4 2.0 1.2 -1.0 1.3 -2.3 1.8 -0.3 -0.2 -0.0 0.2 -0.1 0.7 -1.1 -1.2 1.8 1.7 0.1 0.1 1.8 0.0 0.8
Cholesterol lowering medication 1.0 1.4 6.2 -1.2 -1.0 1.0 -2.5 -0.7 0.7 1.4 1.0 1.7 -1.0 0.3 -1.1 1.6 1.5 -0.7 -0.1 0.1 -0.1 -1.0 -0.9 -2.0
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 5.9 0.1 0.3 1.5 1.3 1.1 0.7 2.3 2.3 1.3 0.9 1.5 2.4 -0.8 -1.7 1.3 2.1 1.5 0.7 1.8 2.1 -1.6
Pain experienced in last month 0.8 1.3 7.1 0.3 -0.5 0.5 -0.6 0.7 1.6 -1.0 -0.4 -0.9 0.9 0.3 -0.6 2.5 2.7 -2.0 -1.2 0.1 -0.2 -0.5 -0.6 -1.2
Supplements: Calcium 0.7 0.8 3.7 1.6 1.2 -0.4 1.1 0.9 0.6 -0.1 -0.4 -1.3 1.2 0.7 0.2 -0.3 -0.5 0.3 -1.0 0.7 1.9 0.8 0.2 -0.1
Basal cell carcinoma (self-reported) 0.8 0.9 4.7 0.1 0.6 0.4 0.3 0.6 -2.2 0.9 0.8 0.6 0.2 0.3 1.8 -0.7 -0.7 2.0 0.9 0.5 0.7 0.7 1.1 -1.0
Heart attack/myocardial infarction (self-reported) 1.1 1.5 7.1 -1.6 -0.0 0.6 -0.8 1.3 -0.4 2.7 1.8 2.1 -0.2 0.5 0.3 -1.5 -1.8 0.3 0.9 0.4 0.1 -1.5 1.2 0.0
Deep venous thrombosis (DVT) (self-reported) 2.9 3.8 15.0 -0.1 -0.0 -0.4 -3.5 -1.7 1.2 -0.5 -0.9 0.3 -1.6 1.1 -1.0 3.0 3.9 -3.0 -2.5 1.5 -2.4 -1.0 -2.2 -2.0
Heart disease (siblings) 0.6 0.8 5.3 1.0 0.7 0.1 -0.8 -0.1 -0.7 0.3 0.0 0.0 -0.3 0.3 -1.2 2.3 2.3 -0.3 -0.4 0.1 0.0 -0.8 -0.4 -0.6
Alcohol drinker status: Previous 0.3 0.4 1.7 0.1 -0.5 -0.8 0.7 0.3 -0.0 -0.6 0.2 -0.3 -0.1 0.1 0.6 0.8 0.6 0.9 -0.2 0.2 -0.4 1.3 1.0 -0.9
Pack years of smoking 0.4 0.6 2.9 -1.2 -0.2 0.2 -1.3 1.7 -0.5 0.5 0.3 0.5 -0.2 -0.4 -0.9 1.1 1.1 -0.9 0.4 -0.4 -0.3 -0.8 -0.7 -0.3
Impedance of whole body 0.4 1.8 4.4 0.7 -1.1 -0.1 -0.5 -0.6 1.9 1.6 2.1 2.0 -0.4 1.7 2.0 0.6 0.4 0.8 0.7 2.0 -0.4 0.8 1.8 -2.1
Leg fat mass (left) 0.8 3.3 10.1 0.5 2.2 1.5 2.0 2.6 -1.3 2.5 2.0 0.8 1.0 1.6 1.9 -0.8 -1.7 2.6 3.2 1.4 1.4 1.0 1.9 -1.5
Arm predicted mass (left) 0.5 2.3 7.9 -0.2 1.5 2.3 1.9 0.4 -1.3 0.8 1.4 0.9 0.4 -1.1 1.2 -1.4 -2.3 2.5 2.8 -1.5 0.7 1.2 1.8 0.9