TWAS hub - ABCC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.244	0.0780	0.00062	0.165	NA	0.137	NA	0.158	8.4e-08	NA	1.2e-06	NA	1.6e-07
2	TCGA	Colon Adenocarcinoma	0.197	0.0840	0.00095	0.080	0.027	0.082	NA	0.090	2.2e-05	0.01100	1.7e-05	NA	7.1e-06
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.044	0.0271	0.00051	0.040	0.026	0.039	NA	0.039	2.7e-05	0.00062	3.1e-05	NA	3.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Diverticular disease/diverticulitis (self-reported)	6.8	8.1	11.0	2.8	3.3	-2.3
Pulse rate, automated reading	4.6	14.7	28.0	-0.0	4.0	-5.3
Medication: Omeprazole	4.4	5.2	7.7	-2.8	0.6	-2.7
Ulcerative Colitis (UC)	3.6	6.7	16.7	4.1	1.6	1.0
Ulcerative Colitis	3.6	5.2	10.9	3.3	1.9	1.0
Severe depression (siblings)	3.3	3.7	5.8	1.9	2.4	1.2
Worry too long after embarrassment	3.3	5.6	10.3	-2.5	0.0	-3.2
Irritability	3.3	5.6	13.5	0.2	1.8	-3.7
Medication: Omeprazole (e.g. Zanprol)	3.0	3.6	5.5	-2.3	1.0	-2.1
Age at First Birth	2.7	3.9	5.9	0.2	2.4	-2.4
Nervous feelings	2.6	4.9	9.0	-2.1	-1.1	-3.0
Mouth/teeth dental problems: Loose teeth	2.6	3.0	5.2	-1.9	-2.3	-0.6
High cholesterol (Self-reported)	2.6	4.6	8.2	2.9	0.3	2.4
Stomach or abdominal pain in last month	2.5	3.1	5.0	2.1	2.2	0.2
Breastfed as a baby	2.5	3.1	8.9	-3.0	-0.0	-0.7
Guilty feelings	2.5	3.8	4.3	-1.9	-1.9	-2.1
Fractured/broken bones in last 5 years	2.4	3.1	4.0	1.5	2.0	-1.7
Blood clot in the leg (DVT)	2.3	3.0	6.6	-0.8	-2.6	1.3
Neuroticism score	2.2	4.5	9.7	-2.0	-0.0	-3.1
Intelligence (Savage-Jansen 2018)	2.1	6.5	12.2	0.4	3.5	-2.7
Irritable Bowel Disease (IBD)	2.1	4.9	12.3	3.5	1.6	0.0
Major Depression (MDD)	2.1	2.6	6.9	0.2	0.9	-2.6
Worrier / anxious feelings	1.9	3.5	6.7	-1.9	0.6	-2.6
Number of live births	1.9	2.7	7.5	0.6	-0.5	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	6.2	0.6	0.8	-2.5
Number of children fathered	1.8	2.0	4.8	0.8	-0.8	2.2
Supplements: Calcium	1.8	2.0	3.3	-0.8	-1.4	1.8
Age when periods started (menarche)	1.7	4.0	7.2	-2.7	-2.0	0.7
Depression (Nagel 2018)	1.6	2.4	4.2	0.9	1.5	-2.0
Neuroticism (Nagel 2018)	1.6	3.9	10.3	-1.1	0.2	-3.2
LDL Cholesterol	1.6	2.6	4.1	0.1	2.0	-1.9
Serious illness, injury or assault to yourself	1.6	2.0	2.9	-0.9	-1.7	-1.5
Length of working week for main job	1.6	1.8	2.8	1.7	1.0	1.2
Health satisfaction	1.6	2.1	4.3	2.1	1.3	-0.4
Illnesses of father: Heart disease	1.6	2.3	4.3	0.3	2.1	-1.6
Neuroticism	1.5	3.6	9.1	-0.9	1.0	-3.0
Frequency of depressed mood in last 2 weeks	1.5	2.1	5.6	-0.2	0.9	-2.4
Number of incorrect matches in round	1.5	2.4	3.1	-1.8	-1.6	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	3.8	-1.9	0.5	-1.1
Loneliness, isolation	1.5	2.1	2.6	-1.3	-1.6	-1.4
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.5	1.3	0.7	-1.9
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	4.4	-0.6	-2.1	1.1
Alzheimer’s Disease (in mother)	1.4	1.6	2.3	-0.6	-1.5	-1.5
Verbal and Numeric Reasoning (VNR)	1.4	3.4	6.6	0.2	2.6	-1.8
HbA1C	1.4	1.6	4.4	-2.1	0.5	-0.3
Primary Biliary Cirrhosis	1.4	2.0	3.3	1.7	1.8	0.1
Supplements: Zinc	1.4	1.6	3.4	-0.5	-1.8	1.0
Fed-up feelings	1.4	2.5	4.4	1.0	1.5	-2.1
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.0	0.0	1.3	-2.0
Fluid intelligence score	1.4	2.9	5.7	0.5	2.4	-1.7
Suffer from ‘nerves’	1.4	2.3	3.5	-1.8	-0.4	-1.9
Leg pain on walking	1.4	1.7	3.2	-1.4	-0.4	-1.8
Wears glasses or contact lenses	1.4	1.6	3.7	-0.6	1.9	-0.9
Sensitivity / hurt feelings	1.3	2.2	3.5	-1.7	0.1	-1.9
Depression (self-reported)	1.3	1.6	3.5	1.9	1.0	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	4.4	2.1	-0.2	-0.2
Osteoporosis (self-reported)	1.3	1.7	2.2	-1.2	-1.5	1.2
Unable to work because of sickness or disability	1.3	1.6	2.6	1.5	1.6	0.0
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.1	0.9	-0.2	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.9	1.7	-0.9	0.7
Medication: Cholesterol lowering	1.2	1.9	3.4	1.9	0.4	1.4
Eye problems/disorders: None of the above	1.2	1.4	2.5	-0.1	-1.6	1.3
Illnesses of siblings: Diabetes	1.2	1.4	2.2	0.0	1.5	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.1	1.4	0.3	1.5
Medication: Lisinopril	1.2	1.6	4.6	0.3	0.4	2.1
Risk taking	1.2	1.8	4.9	-0.6	-2.2	0.2
Diastolic blood pressure, automated reading	1.2	3.8	7.2	-2.0	0.5	-2.7
Average weekly spirits intake	1.1	1.4	2.1	-1.4	-0.5	-1.4
Diabetes (father)	1.1	1.3	4.0	0.0	-2.0	-0.1
Relative age voice broke	1.1	1.6	3.6	-1.9	-1.1	-0.5
Noisy workplace	1.1	1.3	1.9	-1.1	-0.8	-1.4
Lung cancer (father)	1.1	1.2	1.8	-0.9	-1.0	1.4
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.5	0.7	-0.9	1.6
Age at first live birth	1.1	2.0	4.0	1.1	2.0	-0.8
Ever had bowel cancer screening	1.1	1.2	1.9	0.9	1.0	1.4
Average weekly beer plus cider intake	1.1	1.6	3.8	-1.9	-1.0	0.0
Schizophrenia (2014)	1.0	2.2	4.4	-1.4	-2.1	-0.3
Chronotype (morning person)	1.0	2.3	5.6	0.8	2.4	-0.9
Had other major operations	1.0	1.3	3.0	-1.7	0.2	-0.9
Medication: Simvastatin	1.0	1.4	2.9	1.1	-0.5	1.7
Illnesses of siblings	1.0	1.4	2.2	-1.1	-1.5	0.9
Alcohol intake versus 10 years previously	1.0	1.4	2.5	0.6	1.2	-1.6
Father’s age at death	1.0	1.4	3.6	1.9	-0.1	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	4.2	0.6	0.2	-2.1
Pulse wave peak to peak time	1.0	1.2	2.2	-1.2	-1.5	0.0
Shortness of breath walking on level ground	1.0	1.2	2.5	1.0	1.6	-0.2
Number of full sisters	1.0	1.2	3.3	-0.6	0.1	-1.8
Eye problems/disorders: Cataract	1.0	1.1	1.2	-1.1	1.1	-1.0
Miserableness	1.0	1.7	4.0	-0.3	0.9	-2.0
Worry (Nagel 2018)	0.9	1.8	2.3	-1.5	-1.1	-1.4
HDL Cholesterol	0.9	1.4	2.7	1.2	1.7	0.0
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.9	-0.8	-1.4	-0.7
Angina	0.9	1.2	3.1	-0.7	0.3	-1.8
Hair/balding pattern: Pattern 2	0.9	1.2	1.9	1.3	1.4	0.1
Had menopause	0.9	1.2	3.2	-1.8	-0.5	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	2.0	1.4	0.9	-1.2
Angina (self-reported)	0.9	1.1	3.0	-0.6	0.3	-1.7
Supplements: Vitamin C	0.9	1.1	2.1	-1.4	0.1	-1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.8	-1.3	-0.3	-1.2
Basal cell carcinoma (self-reported)	0.9	1.1	2.8	-0.5	-1.7	0.5
Neuroticism (2016)	0.8	1.1	2.1	0.6	0.9	-1.5
Blood Platelet Count	0.8	9.6	18.3	0.4	4.3	-3.2
Height	0.8	16.3	33.6	-1.2	-5.8	3.7
Systolic Blood Pressure	0.8	4.0	6.1	0.6	2.4	-2.5
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.8	0.1	-0.6	1.7
Hearing difficulty/problems with background noise	0.8	1.3	2.1	-0.1	1.4	-1.4
Illnesses of mother	0.8	1.0	2.5	0.4	1.6	-0.5
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.8	1.4	0.6	1.0
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.5	1.6	0.2	0.8
High blood pressure (siblings)	0.8	1.1	2.2	0.3	1.5	-1.0
Medication: Seretide 50 evohaler	0.8	0.9	1.4	0.6	-0.9	1.2
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.0	0.8	0.4	1.4
Alcohol drinker status: Previous	0.8	0.9	1.6	1.3	0.0	1.1
Pack years of smoking	0.8	1.2	2.2	1.5	0.3	1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.9	-0.6	-1.4	-0.9
Body Mass Index (BMI) (2010)	0.7	1.0	2.7	-1.7	-0.5	-0.2
Fasting Glucose	0.7	0.8	2.1	0.5	-1.4	0.2
Diabetes (mother)	0.7	0.9	2.5	1.6	0.4	-0.2
Hand grip strength (right)	0.7	2.0	3.7	1.4	1.9	0.5
Qualifications: CSEs or equivalent	0.7	0.9	1.8	0.2	-1.0	1.3
Qualifications: None of the above	0.7	1.5	3.6	0.1	-1.9	0.9
Financial difficulties in last 2 years	0.7	0.9	2.3	1.5	-0.6	-0.0
Time employed in main current job	0.7	0.8	1.6	0.9	1.2	-0.2
Qualifications: A levels/AS levels or equivalent	0.7	1.6	2.9	1.0	1.7	-1.0
Prospective memory result	0.7	0.8	1.8	-0.2	-1.3	0.8
Glaucoma (self-reported)	0.7	0.8	1.1	0.8	0.9	-1.1
Birth weight	0.7	1.5	4.5	0.1	2.1	-0.1
Exposure to tobacco smoke outside home	0.7	0.9	1.6	-1.3	-0.9	-0.3
Alcohol intake frequency.	0.7	1.7	2.4	1.2	1.5	-1.1
Chest pain or discomfort	0.7	1.1	2.4	-0.8	0.3	-1.6
Average weekly champagne plus white wine intake	0.7	1.0	2.6	-0.5	0.0	-1.6
Medication: Bendroflumethiazide	0.7	1.1	2.1	1.0	1.4	-0.2
Heart disease (siblings)	0.7	0.8	1.9	1.4	0.7	0.4
Bipolar Disorder (2018)	0.6	0.9	2.2	-0.5	-1.5	-0.4
Crohns Disease (2017)	0.6	1.2	3.0	1.7	0.7	-0.5
Reaction Time	0.6	1.1	2.1	-1.5	-0.7	-0.7
Crohns Disease (2012)	0.6	0.9	2.2	0.6	1.5	-0.5
Ever had hysterectomy (womb removed)	0.6	0.7	1.4	0.2	0.8	1.2
Pack years adult smoking proportion	0.6	0.9	1.8	1.3	0.0	0.9
Average weekly fortified wine intake	0.6	0.6	1.2	0.6	0.7	-1.1
Medication: Levothyroxine sodium	0.6	1.0	2.7	1.6	0.3	0.6
Asthma	0.6	1.2	2.5	-0.2	1.0	-1.6
Pulse wave Arterial Stiffness index	0.6	0.7	1.4	0.8	1.2	-0.1
Standing height	0.6	6.2	13.5	-2.1	-3.7	0.8
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	1.8	-0.8	-0.6	-1.3
Qualifications: College or University degree	0.6	1.8	3.6	1.2	1.9	0.6
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.1	-0.2	-1.4	-0.2
Medication: Aspirin	0.6	0.8	1.5	-1.2	0.2	0.9
Commuting to job workplace: Walk	0.6	0.6	1.1	-0.6	-0.6	1.1
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.2	-1.5	-0.9	-0.0
Breast cancer (self-reported)	0.6	0.7	1.2	-0.5	-1.1	-0.8
Osteoarthritis (self-reported)	0.6	0.8	1.2	1.1	1.1	-0.0
Medication: Aspirin	0.6	0.8	1.4	-1.2	0.1	1.1
Medication: Gliclazide	0.6	0.6	1.0	0.4	0.8	-1.0
Smoking status: Current	0.6	1.0	1.4	-1.2	-1.0	-0.7
Hearing aid user	0.6	0.7	1.3	1.1	-0.7	0.5
Depressed Affect (Nagel 2018)	0.5	1.0	2.5	0.3	0.6	-1.6
Hand grip strength (left)	0.5	1.4	3.3	1.0	1.8	0.1
Relative age of first facial hair	0.5	1.1	1.5	-1.1	-1.2	-0.8
Taking other prescription medications	0.5	0.7	1.7	-0.1	0.6	-1.3
Sitting height	0.5	3.4	6.2	-1.7	-2.5	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	2.0	1.0	-0.7	1.4
Mouth/teeth dental problems	0.5	0.7	1.0	-1.0	0.6	-0.9
Allergy	0.5	1.2	1.8	1.3	-0.2	1.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	2.6	-1.0	-1.0	-1.6
Pulse rate	0.5	0.9	1.8	0.3	0.9	-1.3
Mouth/teeth dental problems: Dentures	0.5	0.9	2.4	1.6	0.5	0.2
Gout (self-reported)	0.5	0.7	1.8	0.4	1.4	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	0.9	-0.9	0.6	-1.0
Medication: Blood pressure	0.5	0.8	1.2	1.1	0.7	0.9
Medication: Ibuprofen	0.5	0.6	1.2	-1.1	0.4	-0.6
Medication: Allopurinol	0.5	0.7	1.3	-1.2	0.8	0.1
Comparative height size at age 10	0.5	2.7	6.0	-0.4	-2.4	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.5	-0.5	0.4	-1.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.1	-0.3	1.1	0.8
Asthma (self-reported)	0.5	1.0	1.8	0.0	1.1	-1.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.6	-0.5	0.0	1.3
Number of operations (self-reported)	0.5	0.8	2.0	-1.4	0.4	-0.3
Ever depressed for a whole week	0.5	0.6	1.7	-1.3	-0.4	0.2
Commuting to job workplace: Cycle	0.5	0.6	1.7	1.3	0.2	0.4
Bipolar Disorder or Schizophrenia	0.4	1.1	2.3	-0.9	-1.5	-0.2
Breast Cancer	0.4	1.0	2.6	-0.6	0.3	-1.6
Bipolar Disorder (2011)	0.4	0.4	0.9	0.6	0.0	0.9
Blood Red Count	0.4	4.1	9.5	-0.0	1.6	-3.1
Hypothyroidism (self reported)	0.4	0.8	1.8	1.4	-0.6	0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.3	0.8	0.0	-1.1
Hearing difficulty/problems: Yes	0.4	0.6	1.1	0.1	0.9	-1.1
Vitamin and mineral supplements	0.4	0.5	0.9	0.9	0.8	0.1
Medication: Metformin	0.4	0.6	1.3	1.1	0.7	-0.0
Current tobacco smoking	0.4	0.6	1.3	-0.7	-1.1	-0.4
Maternal smoking around birth	0.4	0.6	0.8	-0.6	-0.8	0.9
Forced vital capacity (FVC)	0.4	1.5	2.1	-1.1	-1.4	-1.1
Heart attack	0.4	0.5	0.7	-0.4	0.8	-0.8
Pain all over the body in last month	0.4	0.4	1.1	1.0	-0.3	0.2
Happiness	0.4	0.4	0.7	0.2	-0.9	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.7	-0.8	0.3	-0.7
Migraine (self-reported)	0.4	0.5	1.2	1.1	0.5	-0.2
Overall health rating	0.4	0.9	2.7	-0.2	-0.3	-1.6
Age at last live birth	0.4	0.6	1.3	0.6	1.2	-0.4
Family relationship satisfaction	0.4	0.5	1.2	1.1	0.5	-0.1
Smoking status: Previous	0.4	0.5	1.4	-0.5	-0.0	1.2
Average weekly red wine intake	0.4	0.7	1.2	-0.7	1.1	-0.6
Long-standing illness, disability or infirmity	0.4	0.6	1.4	0.6	1.2	-0.3
Friendships satisfaction	0.4	0.6	1.4	-0.1	1.2	-0.5
Number of self-reported non-cancer illnesses	0.4	0.7	1.2	1.1	0.9	0.1
Mother’s age at death	0.4	0.5	0.8	-0.7	-0.5	0.9
Age started oral contraceptive pill	0.4	0.6	1.6	-0.2	0.0	-1.3
Smoking Status	0.3	0.6	0.8	-0.9	-0.8	0.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	-1.0	0.2	-0.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.6	0.8	0.5	-0.3
Medication for hormone replacement therapy	0.3	0.3	0.6	-0.5	0.8	0.2
Medication: Co-codamol	0.3	0.4	0.6	0.6	-0.7	-0.4
Townsend deprivation index at recruitment	0.3	0.5	1.0	-1.0	-0.5	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	0.9	-0.0	1.2
High blood pressure	0.3	0.8	1.2	0.8	1.1	0.8
Multivitamins +/- minerals	0.3	0.4	1.0	-0.4	-1.0	-0.2
Past tobacco smoking	0.3	0.6	0.9	0.9	-0.2	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.1	0.2	0.5	-1.0
Medication: Ramipril	0.3	0.3	0.5	0.1	0.7	-0.7
Medication: Lansoprazole	0.3	0.3	0.7	-0.5	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	1.3	-0.5	-1.1	-1.2
Tense / ‘highly strung’	0.3	0.5	1.3	-0.3	-1.1	0.2
Medication: Paracetamol	0.3	0.6	1.1	0.5	-0.5	-1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.0	1.0	0.9	0.5
Number of full brothers	0.3	0.4	0.5	-0.5	0.7	0.6
Medication for pain relief, constipation, heartburn	0.3	0.5	0.9	1.0	-0.4	0.7
Neck or shoulder pain in last month	0.3	0.4	0.7	0.8	0.6	0.3
Mean time to correctly identify matches	0.3	0.6	1.4	-1.2	-0.1	-0.7
Hypertension (Self-reported)	0.3	0.8	0.9	1.0	0.7	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	-0.2	0.8	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.3	-0.3	-1.1	-0.6
Ever taken oral contraceptive pill	0.3	0.4	1.0	-0.3	0.0	-1.0
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	-0.0	0.1	-1.1
Illnesses of father: High blood pressure	0.3	0.4	0.9	-0.3	-0.4	0.9
Schizophrenia (2018)	0.2	0.4	0.6	-0.8	-0.8	0.1
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	-0.1	0.1	0.9
Ovarian Cancer	0.2	0.2	0.5	0.1	0.3	0.7
Prostate Cancer	0.2	0.3	0.9	-0.0	-0.9	0.2
Mean Putamen Volume	0.2	0.3	0.5	-0.7	0.3	-0.4
Lupus	0.2	0.3	0.4	0.4	-0.6	0.4
Rheumatoid Arthritis	0.2	0.3	0.7	0.4	0.2	0.8
Triglycerides	0.2	0.3	0.5	0.5	-0.7	0.1
Heel T-Score	0.2	1.7	4.0	-0.0	1.0	2.0
Waist Hip Ratio (WHR)	0.2	1.1	2.4	-0.4	-0.8	-1.5
Lung FEV1/FVC ratio	0.2	1.0	2.7	-1.6	-0.2	-0.6
Lung FVC	0.2	1.1	2.9	-0.5	-0.2	-1.7
Impedance of leg (right)	0.2	0.8	1.9	-1.4	-0.5	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.8	-0.5	0.6	-0.9
Chronic bronchitis/emphysema (father)	0.2	0.3	0.4	0.6	-0.6	0.2
High blood pressure (mother)	0.2	0.3	0.6	-0.4	-0.7	-0.3
Impedance of leg (left)	0.2	0.7	2.0	-1.4	-0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.5	-0.7	0.2	-0.1
Diabetes (self-reported)	0.2	0.3	0.6	0.8	-0.0	-0.6
Impedance of arm (right)	0.2	1.0	1.5	-1.1	-1.2	0.3
Trunk predicted mass	0.2	0.9	2.1	0.4	-1.5	0.6
Hair/balding pattern: Pattern 4	0.2	0.4	1.1	0.1	1.0	0.2
Loud music exposure frequency	0.2	0.2	0.4	-0.1	-0.3	-0.7
Medication: Amlodipine	0.2	0.2	0.4	-0.3	-0.6	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.7	1.8	-0.3	-1.4	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.6	0.1	-0.0	0.7
Heart disease (mother)	0.2	0.3	0.4	-0.7	-0.5	0.3
Mood swings	0.2	0.4	0.7	0.7	0.8	-0.1
Back pain experienced in last month	0.2	0.3	0.4	-0.4	-0.5	-0.6
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.3	-0.5	0.4	-0.5
Medication: Paracetamol	0.2	0.3	0.6	0.3	-0.5	-0.8
Alcohol drinker status: Never	0.2	0.2	0.4	0.4	0.7	0.3
Ever smoked	0.2	0.4	1.1	-1.0	0.4	0.1
Cholesterol lowering medication	0.2	0.3	0.6	-0.4	-0.3	0.8
Pain experienced in last month	0.2	0.3	0.7	-0.5	-0.3	0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.4	-0.3	0.6	-0.7
Blood White Count	0.1	1.1	2.8	1.7	0.5	0.3
BMI	0.1	0.3	0.8	0.5	0.9	-0.2
Respiratory disease	0.1	0.2	0.3	-0.6	-0.4	-0.5
Number of treatments/medications taken	0.1	0.1	0.2	-0.0	0.4	-0.3
Systolic blood pressure, automated reading	0.1	0.3	0.5	-0.2	0.7	-0.7
Leg fat-free mass (left)	0.1	0.5	1.3	0.2	-1.1	0.5
Trunk fat percentage	0.1	0.3	0.8	-0.2	0.3	0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	0.3	0.6	0.1
Medication: Atenolol	0.1	0.2	0.3	0.6	0.2	0.4
Body mass index (BMI)	0.1	0.4	0.8	0.6	0.9	0.3
Leg predicted mass (left)	0.1	0.5	1.3	0.3	-1.1	0.5
Trunk fat mass	0.1	0.4	0.8	-0.4	-0.4	0.9
Alcohol usually taken with meals	0.1	0.1	0.3	0.2	0.5	-0.3
Weight	0.1	0.4	0.6	-0.2	-0.8	0.6
Arm fat percentage (right)	0.1	0.5	0.8	0.4	0.9	0.7
Trunk fat-free mass	0.1	0.9	2.0	0.4	-1.4	0.6
Hip circumference	0.1	0.3	0.4	0.2	-0.5	0.7
Falls in the last year	0.1	0.1	0.3	0.5	-0.2	0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.3	-0.4	-0.4	-0.5
Impedance of arm (left)	0.1	0.7	1.2	-1.1	-0.8	0.4
Birth weight of first child	0.1	0.2	0.4	0.1	-0.7	0.3
Peak expiratory flow (PEF)	0.1	0.2	0.4	-0.5	-0.2	-0.6
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	0.5	-0.5	-0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.3	0.1	0.5	-0.6
Headache pain in last month	0.1	0.3	0.7	0.2	0.2	-0.8
Body fat percentage	0.1	0.3	0.6	-0.2	0.5	0.8
Leg fat percentage (right)	0.1	0.3	0.6	-0.3	0.8	0.3
Arm fat-free mass (right)	0.1	0.5	0.9	0.6	-0.9	0.6
Comparative body size at age 10	0.1	0.3	0.8	0.1	-0.0	0.9
Emphysema/chronic bronchitis	0.1	0.2	0.4	-0.6	0.2	-0.3
Whole body fat mass	0.1	0.3	0.6	-0.3	-0.2	0.8
Arm predicted mass (right)	0.1	0.4	0.7	0.6	-0.9	0.5
Had major operations	0.1	0.1	0.2	-0.4	-0.1	-0.4
Knee pain experienced in last month	0.1	0.2	0.4	0.1	-0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.3	0.2	-0.5	-0.3
Whole body fat-free mass	0.1	0.6	1.4	0.4	-1.2	0.5
Leg fat-free mass (right)	0.1	0.7	1.5	0.3	-1.2	0.7
Arm fat percentage (left)	0.1	0.6	1.0	0.5	1.0	0.7
Diabetes diagnosed by doctor	0.1	0.1	0.2	0.4	-0.1	-0.4
Qualifications: nursing, teaching	0.1	0.2	0.3	0.0	0.6	0.4
Medication for cholesterol	0.1	0.2	0.5	0.7	0.2	0.3
Mineral and other dietary supplements	0.1	0.2	0.5	0.2	-0.1	-0.7
Illnesses of father: None of the above (group 1)	0.1	0.2	0.5	0.1	0.2	0.7
Whole body water mass	0.1	0.7	1.5	0.4	-1.2	0.6
Leg predicted mass (right)	0.1	0.7	1.6	0.2	-1.2	0.6
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.4	0.3	0.1
Medication: Blood pressure	0.1	0.2	0.5	-0.3	0.3	-0.7
Medication: Atorvastatin	0.1	0.2	0.5	0.7	0.2	-0.1
Basal metabolic rate	0.1	0.5	1.2	0.3	-1.1	0.6
Leg fat percentage (left)	0.1	0.2	0.3	-0.4	0.5	0.5
Arm fat-free mass (left)	0.1	0.6	1.5	0.5	-1.2	0.4
Myopia	0.1	0.1	0.2	0.3	0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.4	0.5	-0.5	-0.7	-0.6
Impedance of whole body	0.1	0.7	1.4	-1.2	-0.7	0.2
Arm predicted mass (left)	0.1	0.5	1.2	0.4	-1.1	0.3
Alzheimer’s Disease (in father)	0.0	0.0	0.1	-0.1	0.2	0.3
Coronary Artery Disease (CAD)	0.0	0.1	0.1	0.1	0.3	0.3
Blood Eosinophil Count	0.0	0.4	0.5	0.5	0.7	-0.6
Allergy or Eczema	0.0	0.1	0.2	-0.1	0.0	0.4
Cardiovascular Disease	0.0	0.0	0.1	-0.2	-0.2	-0.2
Hair Pigment	0.0	1.0	1.6	1.1	0.6	1.2
Tanning	0.0	0.3	0.7	0.4	0.3	0.9
Supplements: Glucosamine	0.0	0.0	0.0	-0.0	0.0	-0.1
Waist circumference	0.0	0.2	0.3	-0.2	-0.4	-0.6
Arm fat mass (right)	0.0	0.1	0.1	0.1	0.3	0.4
Exposure to tobacco smoke at home	0.0	0.1	0.1	0.3	-0.3	-0.1
Pulse wave reflection index	0.0	0.0	0.1	0.1	-0.3	-0.2
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	0.2	-0.2	0.3
Leg fat mass (right)	0.0	0.1	0.3	-0.5	-0.1	0.2
Arm fat mass (left)	0.0	0.2	0.3	0.3	0.5	0.4
Financial situation satisfaction	0.0	0.1	0.1	-0.2	-0.4	0.1
Leg fat mass (left)	0.0	0.2	0.3	-0.5	-0.2	0.5

Hub : Genes

ABCC2

Models

Trait associations