Hub : Genes

ABHD6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0840	0.0380	4.5e-03	0.057	0.017	0.042	0.035	0.045	1.8e-07	3.0e-03	6.2e-06	3.6e-05	3.1e-06
2	GTEx	Adipose Visceral Omentum	0.1470	0.0680	6.7e-03	-0.002	NA	-0.005	NA	0.001	4.1e-01	NA	9.1e-01	NA	2.6e-01
3	GTEx	Artery Aorta	0.1420	0.0510	7.5e-04	0.034	NA	0.083	NA	0.083	5.7e-03	NA	2.5e-05	NA	2.6e-05
4	GTEx	Artery Tibial	0.0990	0.0364	3.2e-04	0.055	NA	0.054	NA	0.078	4.0e-05	NA	4.5e-05	NA	1.0e-06
5	GTEx	Esophagus Mucosa	0.0600	0.0260	7.5e-03	0.062	NA	0.004	NA	0.034	5.5e-05	NA	1.7e-01	NA	2.5e-03
6	GTEx	Esophagus Muscularis	0.1050	0.0430	3.6e-03	0.008	NA	0.029	NA	0.019	9.9e-02	NA	6.6e-03	NA	2.4e-02
7	GTEx	Nerve Tibial	0.2406	0.0644	2.4e-07	0.154	NA	0.163	NA	0.145	4.5e-11	NA	1.3e-11	NA	1.9e-10
8	GTEx	Skin Sun Exposed Lower leg	0.0850	0.0360	3.3e-03	0.012	NA	0.034	NA	0.025	3.0e-02	NA	7.5e-04	NA	3.3e-03
9	ROSMAP	Brain Pre-frontal Cortex	0.1013	0.0303	4.7e-07	0.013	0.063	0.057	0.065	0.051	6.3e-03	1.7e-08	6.9e-08	8.8e-09	3.1e-07
10	YFS	Blood	0.0208	0.0083	2.9e-04	0.015	0.010	0.016	0.013	0.018	6.2e-06	2.1e-04	4.9e-06	3.2e-05	8.4e-07
11	TCGA	Breast Invasive Carcinoma	0.0429	0.0201	7.3e-04	0.011	0.009	0.008	NA	0.009	1.8e-03	4.3e-03	7.6e-03	NA	5.7e-03
12	TCGA	Colon Adenocarcinoma	0.0480	0.0260	6.4e-03	0.048	0.038	0.042	NA	0.037	9.5e-04	3.0e-03	1.9e-03	NA	3.1e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0548	0.0330	2.5e-03	0.004	0.019	0.023	NA	0.004	1.0e-01	2.7e-03	1.1e-03	NA	1.1e-01
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0870	0.0410	8.6e-04	0.071	0.029	0.010	NA	0.035	7.2e-05	8.1e-03	8.0e-02	NA	4.3e-03
15	TCGA	Brain Lower Grade Glioma	0.0866	0.0424	1.7e-04	0.037	0.034	0.036	NA	0.027	3.9e-05	8.8e-05	5.1e-05	NA	4.7e-04
16	TCGA	Prostate Adenocarcinoma	0.0968	0.0420	9.6e-07	0.089	0.061	0.063	NA	0.072	1.5e-09	5.8e-07	3.3e-07	NA	5.3e-08
17	TCGA	Thyroid Carcinoma	0.1450	0.0500	1.6e-13	0.170	0.159	0.150	NA	0.162	2.9e-16	2.6e-15	2.0e-14	NA	1.4e-15
18	TCGA	Uterine Corpus Endometrial Carcinoma	0.1770	0.1000	4.5e-03	0.133	0.081	0.077	NA	0.130	1.5e-04	2.9e-03	3.6e-03	NA	1.8e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	1.2	1.9	6.6	-1.5	-1.5	1.0	0.4	1.5	2.2	0.5	2.2	-2.6	1.4	-0.4	-1.4	-0.4	2.4	0.2	0.0	0.3	0.2
Bipolar Disorder or Schizophrenia	0.9	2.1	7.9	-0.9	-2.0	0.2	-0.7	0.9	2.3	1.1	1.5	-1.6	1.9	0.1	-0.3	0.4	2.8	-1.2	0.8	1.8	1.7
Depressed Affect (Nagel 2018)	0.8	1.6	5.6	0.3	2.4	0.9	-0.1	-1.1	-0.4	0.0	-1.4	1.5	-1.8	-1.9	2.2	0.1	-2.1	0.1	-0.9	-0.4	-0.5
Depression (Nagel 2018)	0.6	0.8	1.9	1.3	0.2	1.2	-0.9	-0.2	0.4	0.5	0.7	0.7	0.8	0.9	0.5	1.4	0.8	-1.3	0.7	1.2	1.3
Intelligence (Savage-Jansen 2018)	0.4	1.2	6.2	1.4	-1.1	1.4	0.9	1.5	1.7	2.5	-0.7	-0.4	0.4	0.3	-1.3	-0.6	1.0	0.6	-0.7	-0.2	-0.2
Neuroticism (Nagel 2018)	1.0	2.3	8.5	-0.1	2.9	0.2	-0.6	-1.7	-1.3	-0.4	-1.5	1.5	-2.1	-2.4	2.3	-0.7	-2.3	-0.1	-1.0	-0.2	-0.4
Schizophrenia (2018)	0.7	1.4	4.2	0.0	-1.4	-0.1	-1.3	-0.0	1.2	1.1	0.2	-0.0	1.4	0.4	0.7	0.8	1.7	-1.7	1.1	2.0	2.1
Schizophrenia vs Biploar Disorder	0.8	1.1	3.4	1.2	-0.9	0.4	-0.8	-0.6	-1.3	0.4	-1.5	1.0	-0.9	-0.9	1.2	1.9	-0.4	-1.0	-0.8	1.1	1.0
Worry (Nagel 2018)	2.4	5.1	15.3	-0.0	3.4	-1.9	-2.9	-3.6	-1.9	-2.2	-1.8	2.6	-0.8	-2.0	3.9	0.2	-1.6	-2.2	2.0	1.7	1.6
Alzheimer’s Disease (in mother)	0.3	0.4	1.7	-0.8	0.3	0.9	0.3	-0.3	-0.5	-0.1	0.3	0.3	-0.1	1.3	-0.2	-0.6	-1.1	0.3	-0.2	-0.7	-0.6
Alzheimer’s Disease (in father)	0.3	0.4	1.1	-0.0	-0.7	-0.2	-0.7	-0.2	-0.3	0.4	-0.7	0.5	0.2	0.7	0.6	0.4	0.4	-1.1	0.4	1.0	1.0
Alzheimer’s Disease (including proxy)	0.2	0.3	1.5	-0.9	-0.3	0.3	-0.4	-0.7	-1.0	-0.0	-0.1	0.3	0.3	1.2	0.3	-0.5	-0.6	-0.5	0.4	0.3	0.3
Crohns Disease (2017)	0.6	1.3	3.7	-0.3	-0.8	0.8	0.7	1.8	1.1	1.7	1.9	-1.1	1.9	0.5	-1.4	-0.2	1.6	0.3	0.3	0.2	0.1
Irritable Bowel Disease (IBD)	0.9	2.2	7.2	-0.1	-1.0	1.6	1.5	2.7	1.5	2.0	1.6	-2.5	1.3	-1.3	-1.8	-0.6	1.6	0.7	-0.9	-0.1	-0.2
Ulcerative Colitis (UC)	1.0	2.0	7.0	0.0	-1.1	1.4	1.4	2.4	1.7	1.7	0.6	-2.6	0.7	-2.0	-1.5	-0.8	1.3	0.8	-1.3	-0.2	-0.3
Major Depression (MDD)	0.5	0.5	2.6	1.6	-0.4	-0.9	-0.4	-0.6	-0.3	-0.1	-1.6	1.2	-0.2	1.1	0.1	-0.1	-0.4	-0.4	0.1	0.1	0.1
Reaction Time	0.3	0.6	1.8	-0.3	-1.1	0.1	0.5	0.2	0.8	-0.2	1.3	-0.4	0.2	0.8	-1.3	-0.1	0.5	1.2	-0.7	-1.0	-0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.2	1.1	-1.3	0.9	0.3	1.5	0.2	2.1	0.1	-0.4	1.7	1.2	-1.4	0.5	1.5	-0.2	0.4	0.6	0.5
Breast Cancer	1.0	2.5	8.5	-0.8	-1.8	1.5	2.0	2.5	1.1	2.1	2.9	-0.8	0.3	0.6	-2.2	0.3	1.1	1.5	-1.9	-1.0	-1.0
Ovarian Cancer	1.0	1.3	3.2	0.1	-0.9	0.5	1.7	1.4	0.2	0.8	0.5	-1.3	-0.9	-0.3	-1.8	-1.0	-0.1	1.7	-1.8	-1.4	-1.5
Prostate Cancer	0.4	0.6	2.0	0.3	1.4	-0.2	0.5	-0.2	0.6	-0.3	0.7	0.1	-1.2	-1.1	0.9	-0.3	-1.2	0.7	-0.5	-0.7	-0.7
Age at First Birth	0.7	1.1	4.0	0.6	-0.3	0.2	-0.9	0.1	0.7	0.3	0.0	0.7	2.0	1.7	-0.2	0.9	1.4	-1.2	1.8	1.1	1.1
Bipolar Disorder (2011)	1.1	1.1	7.8	-1.2	-0.2	-0.4	0.9	0.9	2.8	0.6	0.6	-1.4	-0.2	-0.3	-0.6	-1.8	0.3	0.7	-0.2	-0.7	-0.7
Body Mass Index (BMI) (2010)	1.7	2.4	7.6	-0.7	0.7	0.8	2.3	1.0	1.4	1.0	-0.0	0.5	-1.3	0.4	-0.4	-1.2	-1.9	2.6	-1.7	-2.7	-2.8
Coronary Artery Disease (CAD)	0.9	1.0	5.4	-0.6	0.6	-1.1	0.3	-0.5	-2.3	-0.9	-0.4	-0.1	-1.2	-0.5	0.5	0.4	-1.9	0.6	-1.5	-0.8	-1.0
Crohns Disease (2012)	0.7	1.2	4.5	0.1	-0.6	-0.0	0.8	1.5	1.9	1.1	2.1	-0.6	1.3	1.2	-1.2	-0.0	1.5	0.9	0.5	-0.2	-0.3
Mean Putamen Volume	1.9	2.2	4.4	1.4	1.1	-0.9	-2.1	-1.6	-0.9	-1.1	-1.0	1.6	0.8	-0.7	1.9	2.1	1.0	-1.9	1.4	1.9	1.9
Fasting Glucose	1.0	1.3	5.7	-1.5	-0.9	-0.4	-0.8	0.3	0.3	-0.2	0.2	-1.4	2.0	-0.7	-0.3	1.3	2.4	-0.9	0.9	1.4	1.2
HbA1C	2.2	2.5	6.9	-0.6	0.0	2.1	2.4	1.9	0.6	1.4	2.6	-0.8	-0.7	0.9	-1.9	-0.5	-0.1	2.2	-2.1	-1.3	-2.1
HDL Cholesterol	1.1	1.9	4.8	-0.8	1.1	0.4	1.1	-0.1	-0.7	0.8	-1.4	-0.4	-2.2	-1.8	0.3	-2.1	-2.1	1.6	-1.6	-1.7	-1.8
LDL Cholesterol	0.9	1.5	7.3	-1.9	0.6	0.9	1.3	1.5	1.5	1.0	2.7	-1.9	0.2	-0.5	-0.7	-1.3	0.1	0.8	-0.4	-0.5	-0.2
Lupus	7.4	11.2	22.9	3.2	-0.5	-3.3	-4.6	-3.2	-2.0	-2.7	-0.4	3.4	2.5	2.5	2.7	4.3	2.1	-4.8	4.5	4.5	4.3
Neuroticism (2016)	0.7	1.1	4.1	1.8	1.0	0.7	0.8	0.3	0.4	1.6	-2.0	0.6	-0.8	-1.0	0.4	-1.1	-0.7	0.7	-1.1	-1.0	-0.7
Primary Biliary Cirrhosis	1.8	2.5	7.6	-0.1	-1.0	0.1	-1.5	0.4	-0.4	-0.2	1.0	-1.2	2.1	1.2	0.1	2.3	2.2	-2.6	0.9	2.8	2.8
Rheumatoid Arthritis	1.7	2.3	11.2	-0.3	2.0	0.4	-0.0	-1.5	-3.3	-1.6	0.1	1.7	-2.3	-1.1	1.8	0.1	-2.7	0.4	-0.5	-0.9	-0.9
Schizophrenia (2014)	0.8	1.7	5.2	-0.4	-2.0	-0.7	-1.4	-0.1	1.4	1.0	-0.4	-0.2	0.9	0.5	0.8	0.8	1.9	-1.9	0.7	2.3	2.2
Triglycerides	0.8	1.3	5.7	0.1	-0.9	0.6	0.5	1.3	1.7	0.6	2.4	-0.2	1.7	1.5	-0.7	1.2	1.5	-0.4	0.6	0.5	0.4
Type 2 Diabetes (T2D) (2012)	1.0	1.1	3.4	-0.5	-1.3	-1.3	-0.3	1.0	1.2	1.0	-0.0	-1.8	0.7	-0.7	-0.0	0.5	1.5	-1.3	0.5	1.5	1.5
Ulcerative Colitis	0.7	0.9	3.9	-0.2	-1.1	0.5	-0.1	1.1	0.9	0.6	-0.5	-2.0	1.2	-1.3	-0.3	0.7	1.7	-0.6	0.3	1.1	1.0
Blood Eosinophil Count	0.7	5.3	14.8	-0.7	-2.2	-2.3	-3.3	-1.4	-1.1	-2.6	-0.3	-1.6	1.4	-0.2	0.5	2.8	2.4	-3.6	1.7	3.7	3.9
Blood Platelet Count	6.3	73.1	282.2	-3.8	14.7	-3.8	-0.4	-10.0	-6.6	-8.9	-9.0	10.6	-11.8	-1.5	11.0	-4.8	-16.8	3.1	-0.2	-6.4	-6.1
Blood Red Count	3.5	33.7	79.9	3.8	-3.2	-4.5	-7.4	-2.6	-1.0	-2.8	1.4	2.5	7.3	4.5	2.0	7.8	7.9	-8.0	7.7	8.9	8.9
Blood White Count	0.1	1.0	3.6	-1.4	0.8	1.4	0.6	-0.1	0.5	-0.4	-1.9	-0.3	-0.6	1.9	0.2	-0.7	-1.3	1.1	0.2	-1.1	-1.0
Heel T-Score	0.6	4.6	31.5	2.9	2.9	-2.4	-0.9	-1.9	0.8	-1.3	1.2	5.6	-0.3	0.8	2.8	2.4	-0.6	0.4	2.2	-0.2	-0.3
BMI	0.9	5.3	11.9	-1.9	2.2	3.5	2.7	0.8	-0.6	1.2	0.1	-0.5	-2.8	-1.7	0.0	-1.9	-3.1	3.1	-3.2	-3.2	-3.2
Height	0.8	15.7	58.8	0.8	-5.5	3.3	-0.7	4.3	0.5	4.9	2.4	-2.5	6.1	2.8	-3.0	5.0	7.7	-2.7	2.2	4.4	4.2
Waist Hip Ratio (WHR)	1.3	5.9	16.5	0.7	0.1	-3.4	-2.8	-2.3	0.4	-3.3	-1.5	0.7	2.2	3.4	2.3	2.0	0.8	-2.9	4.1	2.7	2.8
Systolic Blood Pressure	0.6	3.2	11.1	-1.3	1.5	-0.3	1.9	-0.3	0.1	-1.2	0.0	0.0	-2.4	0.4	-0.6	-1.0	-3.1	2.6	-1.4	-3.3	-3.3
Smoking Status	0.5	1.3	4.4	-0.7	1.1	1.6	-0.9	-1.3	-1.6	-0.6	-2.1	1.5	-0.8	-0.4	1.5	0.2	-1.5	-0.8	0.2	0.4	0.5
Allergy or Eczema	0.1	0.3	2.0	-0.0	0.5	-1.4	-0.1	-0.4	0.2	0.1	-1.2	-0.0	-0.1	-0.8	0.6	0.7	-0.5	-0.1	-0.2	-0.1	-0.2
Cardiovascular Disease	0.6	2.1	7.3	-1.8	2.7	-0.2	-0.4	-1.9	-0.3	-2.1	-1.3	0.3	-2.1	-1.1	1.8	-0.7	-2.4	0.5	-0.1	-0.8	-0.8
Hypothyroidism (self reported)	3.8	8.8	20.3	1.2	1.4	-2.1	-4.5	-3.4	-1.8	-2.7	-1.7	2.5	1.4	0.2	3.6	3.6	1.1	-4.5	3.7	4.2	4.2
Respiratory disease	0.7	1.5	6.3	1.3	-1.2	2.2	1.6	1.9	1.2	2.5	-0.7	-0.8	0.1	0.0	-0.9	-0.7	0.4	0.8	-1.4	-0.6	-0.6
Type 2 Diabetes (T2D) (2018)	1.7	3.2	8.4	-0.3	-1.8	-0.7	-2.2	-0.6	-0.5	-1.4	0.8	-1.1	2.0	0.9	0.3	2.7	2.5	-2.5	1.9	2.9	2.8
Lung FEV1/FVC ratio	0.3	1.5	10.6	0.5	1.9	-2.1	1.1	0.7	3.3	0.1	1.0	-0.4	-0.6	0.1	0.5	-1.2	-0.4	1.0	-0.3	-0.8	-0.9
Lung FVC	0.5	2.7	9.9	-0.0	1.9	-0.8	1.3	-0.1	-1.0	-1.3	2.0	-0.1	-2.2	-3.1	0.0	-0.5	-1.7	2.0	-2.1	-2.2	-2.2
Neuroticism	0.6	1.4	4.8	-0.7	2.2	0.6	-0.7	-1.2	-0.7	-0.4	-1.5	0.8	-1.1	-2.1	2.2	-0.1	-1.4	-0.7	-0.5	0.5	0.4
Chronotype (morning person)	1.3	3.0	9.9	0.5	-2.4	1.4	1.1	2.4	3.1	2.3	1.8	-1.7	2.0	2.1	-2.0	0.2	2.2	0.5	0.1	0.2	0.1
Hair Pigment	0.1	3.0	10.3	-0.4	-1.1	-2.6	-2.1	-1.1	-1.4	-1.2	0.1	0.3	1.3	0.7	1.2	2.3	0.7	-3.2	1.7	2.5	2.7
Tanning	0.1	1.3	5.0	1.0	1.2	2.2	1.2	0.4	0.0	0.4	0.4	1.3	-1.0	0.3	-0.4	-1.2	-0.8	1.9	-1.0	-1.6	-1.6
Hand grip strength (left)	0.9	2.3	7.1	1.9	0.1	-1.3	-1.6	-1.4	-1.1	-0.2	-1.4	2.7	1.1	1.4	1.3	2.2	0.2	-1.3	2.4	1.5	1.5
Number of treatments/medications taken	0.9	1.6	3.9	-1.3	1.6	2.0	1.0	0.1	-0.9	-0.4	0.4	-0.6	-1.9	-1.4	-0.2	-1.0	-1.7	1.2	-1.9	-1.4	-1.4
Average weekly spirits intake	0.2	0.3	1.8	-1.3	-0.5	-0.2	0.6	0.4	0.4	0.0	0.8	-0.2	-0.3	-0.0	-0.0	-0.6	-0.5	0.6	-0.5	-0.5	-0.5
Sensitivity / hurt feelings	1.3	2.3	5.7	-1.9	0.2	1.8	1.7	1.0	1.1	1.2	-1.8	-1.3	-1.4	-1.1	-0.6	-1.7	-1.5	1.6	-2.4	-1.7	-1.6
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	-0.5	-0.2	1.3	0.1	0.5	0.6	0.8	0.6	0.1	0.9	1.0	-0.3	0.4	0.8	-0.4	0.1	0.3	0.4
Hearing difficulty/problems: Yes	0.3	0.4	2.4	0.8	0.4	0.3	0.1	0.1	0.9	0.0	1.1	-0.2	-0.2	-1.6	0.2	0.9	0.7	0.2	-0.6	-0.1	-0.3
Relative age of first facial hair	0.3	0.6	2.9	0.2	1.3	0.7	0.2	-0.3	-0.5	-0.3	-0.4	-0.3	-1.7	-0.6	0.6	-0.7	-1.6	-0.3	-1.0	-0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	5.4	-1.9	-1.7	0.4	-1.6	-0.2	-0.3	-0.5	-0.4	-1.5	2.2	-0.3	-0.6	0.8	2.3	-1.7	1.0	2.0	2.0
Ever used hormone-replacement therapy (HRT)	1.8	2.3	11.9	0.7	3.5	1.4	-0.6	-1.9	0.8	-1.7	-0.9	2.3	-1.4	-0.8	2.6	-0.5	-1.7	0.2	0.8	-0.4	-0.5
Ever had hysterectomy (womb removed)	1.3	1.5	4.8	-1.5	0.6	-0.2	-1.4	-1.8	-1.9	-2.2	-1.2	0.5	-1.3	-0.1	1.6	0.6	-1.2	-1.2	-0.0	0.7	0.9
Systolic blood pressure, automated reading	0.9	2.5	7.7	-0.6	1.2	0.4	1.6	-0.1	-0.8	-1.0	0.2	-0.4	-2.4	-1.0	-0.8	-0.7	-2.5	2.2	-2.1	-2.8	-2.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.2	-0.9	0.2	1.4	1.2	0.7	0.4	0.9	0.3	-0.5	-1.1	-0.1	-0.5	-0.7	-0.5	1.1	-1.5	-1.1	-1.2
Angina	1.1	1.4	4.3	-0.6	1.0	0.8	1.1	-0.3	-0.4	-0.4	0.4	0.7	-1.5	0.4	-0.7	-1.9	-1.8	1.7	-1.0	-2.1	-2.0
Medication for hormone replacement therapy	1.0	1.1	3.0	1.2	1.5	-0.1	-1.1	-1.0	0.6	-1.1	1.7	1.7	0.4	0.5	1.3	1.1	0.2	-1.1	1.3	0.9	0.8
Vitamin and mineral supplements	0.7	0.9	3.7	0.5	1.6	0.2	-1.1	-1.3	-0.3	-1.1	-0.7	1.5	-0.3	-0.7	1.9	0.4	-0.2	-0.8	0.4	0.8	0.6
Supplements: Zinc	0.7	0.8	3.0	-0.0	-1.3	1.0	1.0	1.2	0.9	0.2	1.4	-1.7	0.3	-0.5	-1.1	0.2	0.3	0.7	-0.5	-0.6	-0.5
Medication: Co-codamol	0.3	0.4	3.7	-1.1	0.3	1.9	0.3	0.3	-0.2	-0.0	0.4	0.2	-0.4	0.1	0.3	0.5	-0.0	0.2	-0.8	-0.1	-0.0
Medication: Metformin	1.3	1.9	7.0	1.1	-1.3	-0.3	-1.4	0.1	0.0	-0.0	0.9	-0.2	1.5	0.4	-0.0	2.5	2.6	-1.7	1.0	2.1	2.0
Diabetes (father)	0.7	0.8	2.4	0.2	0.3	0.3	-1.4	-1.2	-0.2	-1.6	-0.7	0.3	-0.5	0.1	1.2	1.3	-0.1	-1.3	0.3	1.3	1.3
Diabetes (mother)	0.9	1.1	4.0	-0.5	0.7	-0.7	-1.0	-0.6	1.1	-1.1	0.0	-0.4	-0.1	-1.2	2.0	1.9	0.8	-1.0	0.8	1.3	1.2
Severe depression (siblings)	0.7	0.7	2.3	0.2	1.5	1.1	-0.6	-0.1	0.8	0.2	0.3	1.1	1.4	-0.1	0.6	0.9	1.1	-0.4	1.3	0.8	0.8
Pack years adult smoking proportion	1.2	1.9	5.4	-0.6	1.4	-1.0	-1.5	-2.1	-1.5	-2.3	0.4	1.9	0.7	0.8	1.5	1.9	-0.5	-0.8	2.1	0.6	0.6
Impedance of leg (right)	1.0	4.9	11.0	1.9	-1.3	-1.8	-2.5	-1.1	-0.4	-1.8	0.2	1.7	2.1	3.2	1.5	2.8	1.2	-3.3	3.1	3.2	3.2
Leg fat-free mass (left)	0.2	1.3	5.8	-1.5	0.1	2.3	0.9	1.1	-0.1	2.4	-0.0	-1.0	-0.2	-1.9	-0.3	0.0	0.6	1.1	-1.2	-0.5	-0.6
Trunk fat percentage	0.5	2.1	7.0	-0.9	0.9	2.7	1.1	0.3	-0.1	1.5	-1.3	-0.8	-2.3	-2.2	0.6	-0.7	-1.5	1.2	-2.6	-1.1	-1.2
Hand grip strength (right)	0.4	1.1	3.8	0.0	0.1	-1.3	-0.9	-1.4	-1.1	-0.5	-2.0	1.9	0.5	0.8	1.3	0.6	-1.0	-0.3	1.7	0.3	0.3
Townsend deprivation index at recruitment	0.7	1.0	4.5	0.1	-0.7	0.7	-0.4	0.1	0.6	-0.9	2.1	0.5	1.6	1.2	0.0	1.5	1.5	-0.1	1.5	0.5	0.5
Current tobacco smoking	0.7	1.1	3.8	-0.8	1.5	0.0	-0.8	-1.6	-0.2	-1.4	-1.1	1.8	-0.7	0.0	1.9	0.5	-1.6	-0.6	0.7	0.2	0.4
Average weekly fortified wine intake	0.7	0.8	4.1	-0.1	-0.6	-0.1	-0.6	0.4	0.5	0.4	0.5	-0.4	2.0	1.1	-0.6	0.2	1.8	-0.8	1.3	1.0	0.9
Maternal smoking around birth	1.0	1.4	4.4	0.3	-0.5	-1.4	-1.7	-1.3	-1.5	-0.7	0.4	1.0	0.1	-0.7	1.1	2.1	0.3	-1.5	0.8	1.6	1.7
Fed-up feelings	0.8	1.4	7.7	1.5	1.6	-0.7	-1.0	-1.7	-0.2	-0.5	-0.3	2.8	-0.5	-0.3	2.0	1.3	-1.3	-0.7	0.6	0.4	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	7.3	1.3	-0.2	1.2	0.3	0.9	0.9	1.1	2.7	0.1	1.6	1.4	-0.8	0.3	1.1	-0.1	0.6	0.3	0.4
Relative age voice broke	1.0	1.5	3.4	-1.0	1.1	0.4	-1.4	-1.4	-1.1	-1.8	-0.7	-1.1	-1.3	-1.7	1.5	0.9	-0.7	-1.7	-0.3	1.3	1.3
Taking other prescription medications	0.8	1.2	4.8	-0.0	2.2	1.5	-0.8	-1.5	-0.6	-1.0	-0.7	1.9	-0.0	-0.3	1.7	0.5	-1.1	-0.4	0.8	0.2	0.2
Age when periods started (menarche)	1.7	4.1	11.2	2.5	-1.2	-1.1	-2.5	-0.6	-0.1	1.0	-0.5	1.2	2.4	-0.2	0.9	1.9	3.3	-2.8	2.2	3.4	3.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	0.5	-0.5	-0.1	0.1	0.1	0.2	0.4	-0.4	0.3	0.2	0.2	0.1	-0.1	0.3	0.1	-0.1	-0.0	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	5.5	1.9	1.3	-1.4	-1.4	-0.7	0.6	-0.6	1.0	2.1	1.5	0.8	1.6	2.0	1.1	-1.5	2.4	1.8	1.8
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.3	1.3	-0.9	-1.5	-1.8	-1.4	-1.1	-1.0	-1.0	1.0	1.2	0.7	0.5	0.5	0.5	-1.7	1.6	1.6	1.6
Qualifications: CSEs or equivalent	1.5	1.9	5.4	0.1	2.2	-0.5	-1.6	-2.2	-1.0	-2.0	-1.3	1.7	0.0	0.5	2.3	0.5	-0.8	-1.1	2.1	0.8	0.8
Serious illness, injury or assault to yourself	0.7	0.8	3.3	-0.4	0.6	-0.2	-1.2	-1.2	-1.8	-1.5	1.0	1.0	0.0	-0.1	0.9	0.9	-0.5	-1.0	0.5	0.8	1.0
High blood pressure	0.5	1.4	4.9	0.1	1.2	0.9	1.1	-0.4	-0.1	-0.7	-0.7	0.3	-1.4	-0.4	-0.3	-0.9	-1.7	2.0	-1.0	-2.2	-2.2
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.7	-0.1	0.1	-0.9	-0.3	-0.4	-0.5	0.0	-0.9	0.3	1.3	0.3	0.2	0.6	-0.2	-0.3	0.7	0.1	0.1
Multivitamins +/- minerals	0.8	1.1	3.5	-1.1	-1.9	-0.5	0.4	1.1	1.1	0.7	0.9	-1.5	1.1	-0.1	-1.7	0.7	1.7	0.4	0.3	0.0	0.1
Stomach or abdominal pain in last month	3.7	4.6	10.8	0.3	1.9	-0.8	-2.9	-2.9	-2.2	-2.5	-2.0	2.4	-0.0	-0.4	3.3	2.6	-0.9	-2.8	1.8	2.3	2.3
Supplements: Glucosamine	1.2	1.5	4.7	-0.8	-1.4	2.2	1.5	1.5	-0.2	1.2	1.4	-1.5	0.3	0.1	-1.9	-0.9	-0.1	1.3	-1.2	-1.1	-1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	2.4	0.3	0.7	0.8	-0.4	-0.4	0.1	-0.7	-1.0	0.8	0.6	0.4	1.0	0.4	0.5	0.2	1.5	0.3	0.2
Medication: Atenolol	0.5	0.7	3.1	1.0	1.3	0.1	0.2	-0.3	-1.2	-0.4	0.3	1.8	-1.1	0.9	-0.1	-0.0	-1.0	0.4	-0.0	-0.6	-0.6
Medication: Levothyroxine sodium	2.8	4.8	9.8	1.7	1.5	-1.3	-3.1	-2.7	-2.2	-2.0	-0.7	3.0	-0.1	-0.1	2.6	2.6	0.3	-3.0	2.4	2.7	2.7
Sitting height	0.8	5.4	17.6	0.9	-3.0	1.4	-0.7	2.2	-2.7	3.3	1.4	-1.6	3.6	0.6	-2.1	2.2	4.2	-1.9	1.1	2.6	2.6
Chronic bronchitis/emphysema (father)	1.0	1.1	7.9	2.8	0.3	0.6	-1.0	-0.8	0.6	-0.4	0.1	1.8	0.4	0.1	0.8	1.7	0.4	-0.8	0.8	0.9	0.9
High blood pressure (mother)	1.3	1.9	4.3	-1.0	2.0	0.8	1.8	0.6	2.1	1.0	-0.5	0.6	-0.1	0.6	0.4	-1.7	-1.7	2.0	0.4	-2.0	-2.0
Body mass index (BMI)	0.7	2.8	7.3	-1.4	1.8	1.7	1.2	-0.2	-0.2	0.3	-1.0	-0.6	-2.7	-2.7	0.5	-1.3	-2.2	1.9	-2.6	-2.0	-2.0
Impedance of leg (left)	1.0	4.8	11.4	2.2	-1.5	-1.9	-2.3	-1.0	-0.1	-1.5	-0.4	1.6	2.2	3.4	1.3	2.9	1.1	-3.1	3.0	3.0	3.0
Leg predicted mass (left)	0.2	1.3	6.0	-1.4	0.1	2.3	0.9	1.1	-0.1	2.5	0.1	-1.0	-0.2	-1.8	-0.3	0.1	0.6	1.1	-1.2	-0.5	-0.6
Trunk fat mass	0.3	1.4	6.6	-1.1	0.5	2.6	0.8	0.5	-0.4	1.6	-0.8	-0.9	-1.5	-2.0	0.4	0.1	-0.8	0.9	-2.1	-0.6	-0.7
Waist circumference	0.2	0.6	2.8	-1.7	0.8	0.6	-0.5	-0.8	-0.7	-0.9	-1.2	-0.7	-0.6	-0.5	0.9	0.8	-0.6	-0.1	-0.4	0.1	0.2
Number of incorrect matches in round	0.2	0.4	2.3	0.7	-0.2	-0.5	0.0	-0.3	0.0	-1.5	0.6	-0.6	-0.6	-0.9	-0.5	-0.3	0.2	0.5	-0.5	-0.6	-0.8
Past tobacco smoking	0.5	0.9	8.6	1.1	-0.0	-2.9	-1.0	-1.1	0.4	-0.4	0.1	0.3	0.1	-0.7	0.9	0.4	0.4	-0.5	1.1	0.6	0.6
Alcohol usually taken with meals	1.0	1.7	5.7	-1.4	-1.0	1.6	0.9	1.4	-1.1	0.7	1.5	-2.2	-0.3	-0.0	-2.4	-1.2	0.8	0.6	-2.0	-0.6	-0.6
Nervous feelings	1.7	3.2	7.4	-0.6	1.6	-2.0	-2.7	-2.5	-0.9	-2.0	-1.5	0.2	-0.0	-2.3	2.4	0.1	-0.4	-2.5	1.6	2.2	2.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	3.0	-0.5	0.8	0.6	-0.7	-1.1	-0.2	-0.3	-0.1	0.2	-0.4	-1.7	1.2	0.1	-0.6	-0.5	0.0	0.3	0.4
Hearing difficulty/problems with background noise	0.6	1.0	3.1	-0.7	-0.2	1.8	1.4	1.2	0.2	0.7	1.1	-1.1	-0.0	-0.2	-1.2	0.0	0.2	1.3	-1.4	-1.2	-1.4
Hair/balding pattern: Pattern 2	4.0	5.1	14.6	-0.7	1.2	-3.2	-3.0	-3.8	-1.1	-3.6	-1.7	3.2	-0.4	0.4	2.9	2.0	-1.8	-2.0	1.8	1.4	1.5
Had menopause	0.3	0.4	2.3	0.8	0.6	-0.2	-0.3	-0.6	0.1	-0.9	-0.6	0.2	-1.1	-1.5	0.8	-0.4	-0.4	-0.2	-0.5	0.1	0.1
Had other major operations	0.7	0.9	2.2	0.8	-1.5	0.9	0.7	1.3	1.4	1.4	0.1	-1.0	0.6	0.6	-1.0	1.2	1.2	0.3	-0.9	-0.1	-0.0
Forced vital capacity (FVC)	0.2	0.8	6.7	0.4	-0.0	-0.3	0.6	0.9	-1.4	0.7	2.6	-0.2	0.4	-1.1	-0.3	1.1	0.6	0.5	-0.1	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	6.9	0.4	0.3	-2.0	-1.5	-0.9	1.3	-0.8	0.7	1.3	1.6	0.9	1.5	1.4	1.1	-1.4	2.6	1.8	1.7
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.9	0.1	-1.1	-0.5	0.6	0.1	1.4	-0.6	0.7	0.3	0.4	1.2	-0.7	-0.1	-0.1	1.0	0.4	-1.0	-1.0
Qualifications: None of the above	0.3	0.6	2.2	0.3	0.4	-0.7	-0.2	-1.0	-0.6	-1.2	-1.5	0.4	-1.3	0.1	0.9	-0.6	-1.3	-0.0	-0.1	-0.4	-0.4
Financial difficulties in last 2 years	0.9	1.2	2.7	-1.0	0.5	-1.0	-1.6	-1.6	-0.5	-1.1	-0.4	-0.1	0.4	-1.2	1.7	0.8	-0.2	-1.6	1.1	1.3	1.3
Mouth/teeth dental problems	0.3	0.4	1.2	0.6	-0.2	0.6	-0.4	-0.0	0.6	0.9	-0.5	0.5	0.9	0.5	0.5	0.9	0.8	-0.2	1.1	0.6	0.5
Heart attack	1.0	1.3	4.0	-1.7	1.1	0.5	0.6	-0.3	-1.7	-1.2	0.6	-0.0	-2.0	0.0	-0.1	-0.8	-1.9	0.8	-1.2	-1.2	-1.1
Allergy	0.1	0.3	2.7	0.4	0.2	-0.1	-0.4	-0.1	0.4	-0.3	1.6	0.7	-0.3	0.1	0.2	0.0	0.3	-0.3	0.6	0.4	0.5
Pain all over the body in last month	0.5	0.6	3.3	0.2	1.2	0.6	0.4	-0.1	0.3	-0.7	1.3	-0.4	-0.6	-1.8	0.6	-0.3	-0.4	0.7	-0.5	-0.6	-0.7
Diabetes (self-reported)	0.7	1.1	4.3	0.4	-1.3	0.2	-0.9	0.2	-0.0	-0.1	1.7	-0.7	0.9	-0.1	-0.1	2.0	2.1	-1.1	0.5	1.4	1.3
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.1	0.2	1.0	-1.8	-0.7	-0.8	0.5	-0.6	-1.6	0.7	-0.1	0.2	1.2	0.3	-0.6	-0.7	0.7	0.5	0.5
Medication: Ramipril	0.3	0.4	1.4	-0.7	0.6	0.6	0.7	0.2	0.8	-0.2	-0.4	0.1	-0.8	0.7	0.3	-0.4	-0.5	1.2	-0.8	-1.0	-1.1
Medication: Simvastatin	0.7	1.0	3.7	-1.9	0.6	-0.0	0.7	0.1	-0.2	-1.2	0.1	-1.4	-1.7	-1.2	0.3	-0.4	-1.1	0.9	-1.5	-0.9	-0.9
Fluid intelligence score	0.5	1.1	3.9	-0.0	-1.6	1.1	0.5	1.5	-0.1	1.7	0.3	-0.2	1.5	2.0	-1.2	0.7	1.0	-0.1	0.3	0.4	0.4
Illnesses of siblings	0.7	0.9	3.0	1.2	0.4	-1.3	-1.5	-1.5	-0.5	-1.1	-0.6	0.7	0.8	0.8	-0.1	-0.3	0.1	-0.9	1.7	0.7	0.8
Neuroticism score	0.4	0.8	4.7	-0.7	1.7	0.9	-0.3	-0.6	0.0	0.2	-1.2	-0.2	-0.7	-2.2	1.4	-0.9	-0.8	-0.3	-0.5	0.2	0.1
Weight	0.2	1.0	4.7	-1.4	0.1	2.2	0.5	0.7	-0.6	1.6	-0.4	-1.0	-0.6	-1.9	0.2	0.7	0.2	0.6	-1.4	-0.2	-0.3
Impedance of arm (right)	0.3	1.4	5.5	0.4	0.4	0.2	-1.7	-0.8	-0.5	-0.2	-0.3	1.2	0.4	0.8	1.3	0.9	0.4	-2.3	1.0	2.1	2.2
Arm fat percentage (right)	0.9	3.6	10.7	-2.0	2.1	2.4	1.0	-0.4	-0.4	0.6	-1.4	-0.7	-3.3	-3.0	0.9	-1.6	-2.6	1.4	-3.1	-1.6	-1.6
Trunk fat-free mass	0.3	1.5	5.3	-0.6	-1.3	1.7	0.4	1.7	-0.5	2.1	1.2	-0.9	1.8	-0.3	-1.0	1.5	2.3	0.1	0.3	0.7	0.6
Hip circumference	0.3	1.2	4.8	-1.7	0.0	2.2	0.4	0.6	-0.6	1.4	-1.2	-1.6	-0.5	-2.2	0.0	0.2	0.2	0.3	-1.4	0.0	0.0
Time employed in main current job	0.9	1.1	4.7	0.1	0.8	0.1	0.2	-0.7	-2.2	-1.0	-0.7	0.8	-1.9	-0.4	-0.2	-1.2	-1.6	0.5	-1.3	-1.0	-0.9
Alcohol intake versus 10 years previously	2.8	4.1	10.1	0.6	2.2	-1.5	-2.9	-3.0	-1.1	-2.3	-1.7	1.7	-0.4	-1.6	3.2	1.6	-0.5	-2.6	2.0	2.3	2.3
Father’s age at death	1.7	2.3	5.9	-0.0	-0.1	1.2	2.3	1.5	0.4	1.0	1.0	-1.2	-0.6	0.3	-2.0	-2.0	-1.1	2.0	-1.9	-2.4	-2.4
Worrier / anxious feelings	1.0	1.8	6.4	-0.4	2.0	-0.4	-1.4	-1.7	-0.1	-0.7	-2.5	0.6	-0.9	-2.5	2.3	-0.4	-0.6	-1.2	0.1	1.0	0.9
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	7.2	0.1	2.7	-0.8	-1.3	-2.2	-1.4	-1.4	0.1	2.4	-0.1	-0.8	2.5	0.5	-1.4	-0.7	1.3	0.4	0.4
Falls in the last year	0.6	0.8	1.9	-1.2	0.3	1.0	1.1	0.4	-0.5	0.6	-0.4	0.1	-0.5	0.4	-0.8	-0.8	-0.9	1.4	-1.1	-1.3	-1.2
Hair/balding pattern: Pattern 3	0.3	0.4	3.3	1.8	-0.1	0.5	0.1	0.5	-0.3	1.0	0.4	0.5	0.7	-0.2	-0.4	0.5	0.7	0.1	0.2	0.2	0.2
Number of live births	2.1	3.0	9.3	-1.4	0.3	1.7	1.9	0.9	-0.7	0.6	-2.0	-1.5	-2.1	-1.2	-1.0	-2.4	-2.0	1.9	-3.1	-2.0	-1.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	8.6	0.5	0.7	-0.9	1.0	0.9	-0.1	0.5	2.9	0.2	0.4	-0.1	0.0	0.7	0.1	0.9	0.2	-0.6	-0.7
Pulse rate	1.2	1.9	7.3	2.7	0.7	-1.1	-1.9	-1.6	-0.0	-1.2	0.0	1.9	0.3	-0.5	1.4	2.1	0.8	-1.7	0.9	1.5	1.5
Happiness	0.3	0.4	1.2	-0.8	-1.1	-1.0	-0.7	-0.3	-0.4	-0.0	0.5	-0.6	0.5	-0.2	-0.1	0.4	0.6	-0.6	0.5	0.7	0.7
Noisy workplace	0.7	0.9	2.3	-0.5	1.4	0.6	0.6	-0.6	-0.1	-1.0	0.9	1.5	-0.1	0.1	0.1	-0.7	-1.4	1.4	0.6	-1.4	-1.4
Qualifications: A levels/AS levels or equivalent	1.4	3.0	10.8	-1.7	-1.6	0.2	2.0	2.3	1.2	2.2	0.5	-3.3	0.4	-0.1	-2.5	-2.5	0.2	1.7	-1.5	-1.4	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	1.2	0.1	-0.1	-0.2	0.1	0.2	0.7	0.3	-0.4	-0.1	0.1	-1.1	0.0	-0.2	0.1	-0.0	-0.2	0.1	0.1
Mouth/teeth dental problems: Dentures	0.5	0.9	2.1	-0.4	-1.0	-0.3	1.4	1.2	-0.2	0.3	1.1	-0.9	0.1	0.2	-1.4	-1.3	0.2	1.1	-1.1	-1.1	-1.1
Asthma	0.3	0.6	1.9	0.3	-1.2	1.3	0.8	0.9	0.0	1.4	-0.8	-0.8	0.2	0.4	-0.7	-0.6	-0.0	0.5	-0.9	-0.4	-0.4
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	6.0	-1.4	-0.1	2.1	2.0	1.4	0.4	1.4	0.8	-0.3	-0.9	0.4	-1.6	-0.8	-1.0	2.4	-1.8	-2.1	-2.1
Medication: Cholesterol lowering	1.6	2.5	7.7	-2.8	0.5	1.4	2.0	1.3	1.2	0.2	1.7	-1.7	-0.9	-0.4	-0.8	-1.7	-0.7	2.4	-1.6	-2.0	-2.1
Depression (self-reported)	0.8	1.0	2.6	1.2	-1.0	-0.9	-1.1	-0.5	-1.2	-0.2	-0.4	0.2	1.6	0.3	-0.1	0.7	1.1	-1.2	1.6	1.2	1.3
Medication: Lansoprazole	0.6	0.7	3.0	-0.8	0.7	-0.3	-0.4	-1.2	-0.3	-1.2	-0.6	-0.3	-1.7	-1.7	0.5	-0.3	-0.8	0.1	-1.1	-0.4	-0.3
Prospective memory result	0.3	0.4	2.3	0.7	-0.9	0.8	-0.1	0.2	0.7	-0.4	0.4	-0.4	0.3	-0.4	-0.4	1.5	1.1	-0.1	-0.2	0.2	0.2
Lung cancer (father)	1.5	1.7	3.7	-1.0	-0.8	1.1	1.7	1.3	1.9	0.7	0.9	-1.6	-0.1	0.2	-1.9	-1.8	-0.2	1.6	-1.4	-1.6	-1.5
Illnesses of mother	1.5	1.9	5.2	1.1	-1.2	-0.4	-2.2	-1.3	-1.3	-1.1	-0.6	0.1	0.8	-0.4	0.7	1.5	1.2	-2.3	1.0	2.2	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	7.1	1.1	0.5	-1.2	0.4	0.3	-0.5	0.6	2.7	1.1	0.6	0.0	0.3	1.1	0.1	0.5	0.7	-0.2	-0.3
Pulse wave Arterial Stiffness index	1.4	1.7	5.4	1.3	-1.2	1.0	0.3	1.6	1.3	1.0	1.9	-0.7	2.2	1.1	-1.4	1.3	2.3	-0.3	0.7	0.7	0.7
Impedance of arm (left)	0.1	0.6	2.4	0.7	-0.2	0.4	-1.0	-0.3	0.3	0.4	-0.5	0.5	0.3	0.6	0.9	0.6	0.4	-1.5	0.5	1.6	1.6
Arm fat mass (right)	0.6	2.6	7.9	-1.7	1.2	2.6	1.2	0.4	-0.3	1.3	-0.8	-1.0	-2.3	-2.7	0.2	-0.9	-1.6	1.6	-2.8	-1.5	-1.5
Trunk predicted mass	0.3	1.6	5.9	-0.6	-1.3	1.7	0.3	1.6	-0.5	2.0	1.3	-0.9	1.9	-0.2	-1.0	1.6	2.4	-0.0	0.4	0.8	0.7
Standing height	0.8	7.6	26.7	0.0	-3.4	1.6	-1.3	2.1	-1.1	3.0	1.3	-0.8	4.4	1.6	-0.8	4.2	5.2	-2.5	2.2	3.7	3.5
Length of working week for main job	1.1	1.2	4.4	0.4	1.8	-0.5	-0.7	-1.1	-0.7	-0.9	-0.4	2.0	0.0	1.1	2.1	1.1	-0.9	-0.3	1.6	0.5	0.4
Exposure to tobacco smoke at home	1.5	1.7	4.7	0.7	-0.5	0.1	-2.0	-1.3	0.3	-1.4	-0.1	-0.2	0.7	-0.2	1.2	1.8	0.8	-2.2	1.2	2.1	2.2
Breastfed as a baby	0.3	0.4	2.8	0.7	0.2	1.7	0.1	0.3	0.8	0.7	-0.7	0.1	0.9	0.6	-0.4	-0.8	0.3	0.1	0.6	0.1	0.1
Tense / ‘highly strung’	0.5	0.8	1.9	0.5	0.9	-0.3	-1.1	-1.1	-0.1	-1.0	0.9	1.0	0.7	-0.5	1.4	0.4	-0.4	-1.1	1.4	0.9	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.4	1.4	-0.0	1.0	-0.3	0.4	0.6	0.8	-0.1	1.4	1.1	1.9	-0.1	0.9	0.9	-0.9	0.6	0.8	0.9
Hair/balding pattern: Pattern 4	1.1	2.8	8.3	-1.0	-0.5	2.6	2.2	2.6	0.6	2.0	1.4	-2.9	-0.4	-0.8	-1.9	-1.1	0.6	1.6	-1.9	-1.3	-1.4
Birth weight of first child	0.6	1.1	4.8	-2.2	-1.1	-0.2	0.7	1.3	-0.6	0.9	-0.7	-2.0	0.8	0.1	-1.4	-0.5	1.3	0.6	-0.0	-0.2	-0.2
Peak expiratory flow (PEF)	0.2	0.5	2.6	0.9	1.4	-0.3	-0.2	-0.5	-0.1	0.3	0.6	1.5	0.1	-0.3	1.6	0.4	-0.4	-0.1	0.8	0.1	0.0
Pulse wave reflection index	0.9	1.1	5.0	0.1	-0.4	0.7	1.2	1.7	1.4	1.0	1.8	-0.4	1.0	2.2	-1.5	0.1	0.4	0.6	0.2	-0.6	-0.5
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.8	1.5	1.8	-0.7	0.3	-0.8	-1.0	-1.2	0.8	1.9	-0.7	-0.2	0.5	-0.5	-1.4	1.2	0.2	-1.2	-1.3
Loud music exposure frequency	0.2	0.2	1.4	-0.1	0.5	0.1	0.1	-0.2	-0.6	-0.3	1.2	0.2	0.8	0.5	-0.3	0.1	-0.3	0.3	0.6	-0.4	-0.4
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	6.0	-1.7	-0.2	0.1	1.5	1.6	1.3	1.0	1.2	-2.5	0.3	-1.4	-1.5	-1.7	0.5	1.6	-1.2	-1.1	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.9	0.7	-1.1	-0.5	-0.8	-0.9	-0.6	-0.7	0.6	-1.1	-0.2	0.8	-0.3	-1.1	-0.7	-0.5	0.2	0.4
Blood clot in the leg (DVT)	0.5	0.6	1.1	-1.0	1.0	-0.5	0.4	-0.1	0.0	-0.5	-0.9	-0.5	-1.0	0.3	-0.9	-1.0	-0.7	1.0	-0.8	-1.0	-1.0
Medication: Paracetamol	0.4	0.7	2.3	-0.4	1.4	0.5	-0.2	-0.9	-1.5	-0.6	-1.4	0.5	-0.7	-0.8	0.8	-0.8	-1.3	0.0	-0.2	-0.4	-0.3
Headache pain in last month	0.7	1.2	5.6	-2.4	1.2	-1.1	-1.0	-1.3	-1.7	-0.8	-1.2	0.3	-0.4	-1.6	0.9	-1.0	-0.6	-0.8	0.1	0.4	0.4
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.4	1.4	-0.7	-0.8	-1.1	-0.5	-0.6	0.5	-0.8	1.0	1.6	0.9	0.8	1.3	0.7	-1.9	1.7	1.5	1.6
Glaucoma (self-reported)	0.5	0.6	2.6	1.5	-0.7	-0.2	-0.4	-0.2	-0.3	-0.2	0.8	0.5	1.3	1.6	-1.1	-0.3	0.7	-0.1	1.1	0.1	0.1
Gout (self-reported)	1.1	1.5	6.4	-0.2	-0.9	2.5	1.4	1.7	1.1	2.1	-0.4	-1.7	-0.2	-0.5	-1.2	-0.3	0.5	1.0	-1.7	-0.7	-0.8
Hypothyroidism/myxoedema (self-reported)	3.5	6.9	14.9	1.5	1.4	-2.3	-3.9	-3.2	-1.7	-2.4	-1.4	3.0	0.8	0.3	3.1	3.4	0.9	-3.7	3.2	3.4	3.4
Medication: Amlodipine	0.8	1.1	3.9	0.1	-0.9	-0.0	1.6	1.1	0.7	1.1	1.0	-0.5	-0.7	-0.4	-1.1	-1.0	-0.4	1.3	-2.0	-1.4	-1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.8	1.7	0.5	1.3	1.6	0.7	-0.0	1.6	-1.6	0.8	-1.0	0.2	-0.0	-1.5	-1.4	1.6	-1.3	-1.6	-1.6
Birth weight	0.2	0.4	1.7	-1.0	-0.2	-0.8	-0.3	0.3	-0.2	0.2	0.1	-1.3	1.0	-0.6	-0.1	0.3	0.5	-0.9	0.6	0.8	0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.3	0.4	0.6	0.8	1.4	0.8	0.6	1.3	0.3	0.7	-0.5	0.4	-0.5	-0.9	-0.7	1.5	-0.4	-1.4	-1.4
High blood pressure (siblings)	1.6	2.4	5.7	-1.9	0.6	1.2	2.4	1.4	-0.3	0.9	0.0	-1.1	-1.4	-1.4	-0.2	-0.9	-1.6	2.2	-2.2	-2.2	-2.2
Forced vital capacity (FVC), Best measure	0.2	0.8	6.5	0.8	0.1	-0.2	0.6	0.7	-1.3	1.0	2.6	0.5	0.5	-0.8	-0.1	1.0	0.4	0.7	0.2	-0.3	-0.4
Body fat percentage	0.5	1.9	5.9	-1.0	1.1	2.1	0.5	-0.3	-0.5	0.7	-1.7	-0.6	-2.4	-2.3	1.0	-0.4	-1.8	0.8	-2.3	-0.8	-0.8
Leg fat percentage (right)	0.3	1.2	4.2	-0.8	1.4	0.8	-0.2	-1.1	-0.8	-0.9	-1.2	0.3	-2.0	-1.3	1.5	0.3	-2.0	0.1	-1.2	-0.4	-0.4
Arm fat-free mass (right)	0.2	1.1	3.8	-0.3	-1.4	1.2	0.5	1.4	0.3	2.0	0.8	-1.0	1.3	-0.2	-0.9	1.1	1.9	0.6	0.2	0.2	0.1
Exposure to tobacco smoke outside home	0.6	0.8	1.9	1.0	0.1	-0.1	-1.2	-1.3	-0.7	-1.2	0.0	1.1	0.1	-0.8	1.4	1.2	0.1	-1.0	1.0	0.8	0.8
Comparative body size at age 10	1.9	5.1	15.1	-1.8	1.5	2.0	2.7	0.4	-0.7	0.6	-1.2	0.7	-2.6	0.3	-0.3	-2.5	-3.9	3.3	-2.4	-3.7	-3.6
Number of full brothers	1.0	1.3	3.3	1.5	-0.5	-0.6	-0.9	-0.2	-0.9	0.0	1.2	0.9	1.7	1.6	0.2	1.4	0.9	-1.1	1.8	1.2	1.3
Worry too long after embarrassment	0.3	0.6	3.1	-0.6	0.4	1.8	0.4	0.4	0.3	0.7	-0.8	-1.2	0.0	-1.0	-0.4	-1.3	0.3	0.6	-0.4	-0.3	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	6.2	-0.0	-0.6	0.1	-1.7	-0.4	0.8	0.1	0.9	0.7	2.4	1.3	0.8	2.2	2.0	-2.4	1.9	2.5	2.5
Wheeze or whistling in the chest in last year	0.7	1.2	5.1	0.5	1.2	0.4	-0.4	-1.2	-2.2	-1.1	-1.2	2.3	-1.1	0.6	1.1	0.2	-1.7	-0.1	-0.1	-0.3	-0.4
Number of children fathered	0.8	0.9	2.4	-0.6	0.4	0.3	1.0	0.3	-1.1	0.4	-0.7	-0.1	-1.5	-1.0	-0.4	-1.0	-1.5	1.1	-1.4	-1.2	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.9	-0.1	0.1	0.3	1.2	0.9	1.4	0.6	0.2	-0.4	-0.0	0.0	-0.8	-1.3	-0.5	1.4	-0.6	-1.2	-1.2
Age at first live birth	0.9	1.7	4.9	-1.6	-1.7	1.0	0.6	1.5	0.6	1.5	1.3	-0.9	1.9	2.2	-2.1	-0.4	1.4	-0.1	0.9	0.1	0.2
Pulse wave peak to peak time	1.0	1.2	3.5	-1.1	0.8	-0.9	-0.3	-1.3	-1.2	-0.5	-1.8	0.8	-1.9	-0.8	1.3	-1.0	-1.9	0.2	-0.6	-0.5	-0.5
Health satisfaction	0.2	0.2	1.0	-0.7	0.3	0.6	-0.3	-0.5	-1.0	-0.9	-0.7	0.2	-0.3	-0.2	0.1	0.6	-0.4	-0.0	-0.2	0.0	0.1
Shortness of breath walking on level ground	0.2	0.3	2.2	0.6	-0.8	-0.2	-0.3	-0.1	0.0	-0.4	0.9	0.3	0.1	0.2	-0.6	1.5	0.5	-0.3	-0.2	0.3	0.3
Qualifications: College or University degree	1.3	4.1	12.1	-3.4	-2.8	0.4	2.1	2.8	2.1	2.1	0.9	-3.5	1.3	0.0	-2.9	-1.4	1.3	1.4	-1.4	-1.0	-1.1
Eye problems/disorders: None of the above	2.2	2.6	6.2	-1.5	-0.7	-1.8	1.8	1.2	1.2	0.6	-0.0	-2.5	-2.3	-1.9	-0.4	-1.9	-1.0	1.4	-2.4	-1.7	-1.7
Mouth/teeth dental problems: Loose teeth	1.4	1.7	6.6	-0.4	1.4	-1.1	-0.3	-1.8	-1.5	-2.0	-1.1	1.1	-1.7	-0.5	1.2	-1.4	-2.6	0.3	-0.2	-1.0	-0.9
Emphysema/chronic bronchitis	3.4	3.8	9.2	1.3	1.2	-1.0	-2.5	-2.8	-3.0	-3.0	-0.5	3.0	0.5	1.2	2.1	1.6	-0.5	-1.8	2.3	1.6	1.7
Medication for pain relief, constipation, heartburn	1.7	3.0	8.8	1.5	-1.3	-2.4	-1.9	-0.7	0.3	-0.7	-0.0	0.6	2.1	1.5	0.7	1.4	1.9	-2.4	3.0	2.4	2.4
Neck or shoulder pain in last month	3.1	4.3	18.3	2.8	2.0	-0.3	-2.2	-2.4	-0.2	-1.5	-1.2	4.3	0.7	1.1	3.1	2.8	-0.1	-1.6	2.8	1.5	1.5
Medication: Blood pressure	0.9	1.6	5.6	-0.3	1.6	0.0	0.5	-0.8	-0.9	-1.4	-1.0	0.5	-2.4	-1.0	0.1	-1.1	-1.7	1.7	-1.6	-1.6	-1.6
Angina (self-reported)	0.7	1.0	2.8	-0.3	0.8	0.6	0.7	-0.5	-0.6	-0.5	0.2	0.7	-1.2	0.5	-0.6	-1.6	-1.4	1.3	-0.7	-1.7	-1.6
Migraine (self-reported)	0.3	0.4	2.2	1.5	-0.1	0.8	0.8	0.5	0.5	0.7	0.6	0.9	0.3	0.2	0.1	-0.1	-0.1	0.8	-0.1	-0.6	-0.7
Medication: Ibuprofen	0.8	0.9	2.6	-1.1	0.3	1.6	1.2	1.0	0.3	1.1	0.9	-0.1	-0.5	0.2	-1.0	-0.4	-0.2	1.5	-1.2	-1.1	-1.1
Medication: Allopurinol	0.4	0.6	4.1	-0.2	-0.2	2.0	-0.1	0.3	1.1	1.1	-0.7	-0.2	0.4	-0.3	0.6	1.2	0.7	-0.2	0.1	0.5	0.4
Medication: Omeprazole	0.7	0.9	2.6	0.1	0.0	-0.4	-1.2	-1.3	0.4	-0.9	-0.8	1.3	0.6	-0.2	1.6	1.2	-0.0	-1.1	1.1	1.0	0.9
Medication: Seretide 50 evohaler	0.5	0.5	3.7	1.0	-0.2	-0.5	-0.5	-0.7	-1.9	-0.4	-0.2	1.2	-0.0	0.2	0.4	1.3	-0.4	-0.6	0.4	0.2	0.3
Mean time to correctly identify matches	0.5	1.0	2.9	-0.3	-1.3	0.4	1.0	0.7	1.3	-0.0	1.4	-0.8	0.1	0.8	-1.7	0.2	0.7	1.5	-1.2	-1.3	-1.3
Heart disease (mother)	0.1	0.2	1.0	0.1	0.6	-0.4	-0.2	-0.2	0.2	-0.2	0.8	0.4	0.1	-1.0	0.2	0.1	0.1	-0.3	-0.1	0.3	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	4.7	0.2	2.2	0.5	-1.2	-1.7	-0.6	-2.0	-0.5	1.4	-0.4	-0.5	1.6	0.9	-0.9	-0.7	1.0	0.3	0.3
Whole body fat mass	0.4	1.5	5.4	-1.3	0.8	2.3	0.6	0.1	-0.7	1.0	-1.1	-0.8	-1.8	-2.3	0.7	0.0	-1.1	0.8	-2.0	-0.7	-0.7
Leg fat mass (right)	0.3	1.0	3.0	-1.1	1.1	1.4	-0.1	-0.7	-0.7	-0.0	-1.1	-0.2	-1.6	-1.7	1.1	0.5	-1.4	0.3	-1.2	-0.3	-0.3
Arm predicted mass (right)	0.2	1.0	4.0	-0.3	-1.3	1.4	0.6	1.4	0.0	2.0	0.6	-1.1	0.9	-0.4	-0.8	1.1	1.6	0.6	-0.2	0.1	0.1
Pulse rate, automated reading	1.9	6.2	13.8	2.2	1.0	-2.7	-3.7	-3.3	-2.3	-2.4	-1.1	2.4	0.2	-1.9	3.2	3.2	0.6	-3.2	2.0	3.0	3.0
Alcohol intake frequency.	2.4	5.7	14.9	1.7	2.7	-1.4	-3.2	-3.5	-0.5	-3.2	-0.6	3.2	0.5	-0.3	3.9	2.2	-0.5	-2.5	3.1	2.3	2.3
Comparative height size at age 10	1.1	6.1	20.3	-0.3	-2.3	1.2	-1.6	1.2	0.4	1.3	2.2	-0.4	4.0	2.3	-0.4	3.9	4.5	-2.2	2.7	3.4	3.3
Number of full sisters	0.6	0.7	3.8	-0.5	1.3	1.3	0.3	0.3	1.9	0.6	-0.7	0.4	-1.0	-1.1	0.8	0.3	-0.0	0.3	-1.1	0.1	0.0
Suffer from ‘nerves’	0.9	1.3	4.7	0.1	1.5	0.2	-1.6	-1.1	0.4	-0.1	-1.0	0.4	0.7	-1.3	2.2	0.1	0.6	-1.4	1.6	1.7	1.5
Overall health rating	1.6	3.4	17.4	1.6	2.8	-0.5	-1.6	-2.5	-0.4	-2.1	-1.1	4.2	-0.4	0.8	3.1	1.5	-1.5	-0.9	1.8	0.6	0.6
Chest pain or discomfort	0.4	0.6	3.7	-0.6	1.9	0.4	-0.5	-0.7	-0.6	-1.2	-0.0	1.0	-0.8	-0.2	1.2	0.7	-0.6	-0.4	-0.0	0.3	0.3
Had major operations	0.3	0.3	1.7	-0.7	0.0	0.1	0.5	0.6	0.8	-0.0	-0.5	-1.3	0.1	-0.8	-0.5	-0.3	0.3	0.4	-0.4	-0.2	-0.3
Age at last live birth	0.8	1.1	3.7	-1.7	-1.8	0.4	0.6	1.5	0.9	1.8	0.2	-1.9	1.0	0.1	-1.0	-0.2	0.9	-0.6	-0.3	0.5	0.5
Family relationship satisfaction	0.7	0.9	3.4	-1.2	0.1	-0.4	-0.8	-0.6	-0.0	-0.8	1.8	0.5	1.4	1.6	-0.4	0.7	0.6	-0.2	1.5	0.4	0.5
Leg pain on walking	0.6	0.8	3.8	0.7	-1.9	0.1	1.0	1.3	0.1	1.1	0.5	-0.3	-0.5	0.5	-1.2	0.9	0.3	0.7	-1.2	-0.6	-0.5
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	7.1	1.5	2.7	0.9	-1.1	-1.3	-0.1	-0.3	0.0	2.7	-0.3	-0.7	2.2	1.3	-0.1	-0.6	1.2	0.8	0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.3	-0.4	0.6	-0.2	-0.5	-0.4	-1.0	-0.1	0.6	0.8	1.2	1.0	0.5	0.1	-0.1	-0.6	1.5	0.6	0.5
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	3.2	0.3	-1.4	0.1	0.9	1.6	1.0	1.2	1.0	-0.8	1.0	0.9	-1.2	0.1	1.8	0.8	0.1	-0.2	-0.4
Medication: Aspirin	1.2	1.5	4.3	0.0	0.5	1.0	1.5	1.0	1.4	0.7	0.8	-0.5	-1.3	-0.8	-0.9	-1.8	-0.5	1.7	-2.1	-1.6	-1.6
Supplements: Vitamin C	0.7	0.8	3.1	0.4	-1.3	-0.1	0.9	1.1	-1.1	0.6	0.5	-1.8	0.2	0.8	-1.7	-1.1	-0.1	0.4	-0.4	-0.7	-0.6
Knee pain experienced in last month	0.4	0.6	3.4	-0.2	-0.0	1.3	1.0	1.0	1.2	1.9	0.5	0.2	0.0	-0.1	-0.3	-0.3	0.1	0.5	-0.8	-0.4	-0.3
Hypertension (Self-reported)	0.7	2.1	5.5	0.2	1.9	0.9	1.1	-0.7	-0.6	-0.8	-1.4	0.7	-2.0	-0.8	0.2	-1.1	-2.3	2.1	-1.1	-2.3	-2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	0.5	0.3	-0.4	0.2	-0.5	0.9	-0.2	-0.8	1.2	-0.9	-0.4	1.0	-0.1	-0.8	0.2	-0.7	-0.5	-0.6
Illnesses of father: Heart disease	1.4	2.0	5.2	-0.7	-1.1	-1.7	-1.4	-0.2	1.1	-0.5	-0.3	-0.6	2.3	1.4	0.1	1.2	1.8	-1.8	2.2	1.9	1.9
Illnesses of siblings: Diabetes	0.7	0.9	2.8	-1.0	-0.6	-0.5	-1.0	-0.2	-0.1	-1.3	1.7	-0.8	0.9	0.5	-0.0	1.2	1.2	-1.2	0.8	1.2	1.1
Smoking status: Previous	0.5	0.8	8.2	-0.5	-0.4	2.9	0.6	1.2	-0.6	0.7	0.2	-0.8	0.4	0.4	-1.1	-0.1	0.5	0.1	-0.8	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.2	6.7	0.7	0.1	-0.7	-1.5	-0.4	-1.2	0.5	0.0	1.2	1.8	0.7	1.6	1.9	1.8	-1.7	2.6	2.2	2.2
Whole body fat-free mass	0.2	1.1	4.9	-0.9	-0.7	1.9	0.6	1.4	-0.3	2.2	0.6	-0.8	1.0	-0.9	-0.6	0.9	1.6	0.6	-0.3	0.2	0.1
Leg fat-free mass (right)	0.3	1.5	7.0	-1.5	0.0	2.1	1.1	1.2	-0.0	2.6	-0.2	-1.1	-0.1	-1.9	-0.5	-0.2	0.6	1.4	-1.2	-0.7	-0.8
Arm fat percentage (left)	1.0	4.0	11.3	-1.9	1.9	2.4	1.3	-0.2	-0.1	0.8	-1.5	-1.0	-3.4	-3.1	0.8	-1.8	-2.7	1.8	-3.3	-1.9	-1.9
Average weekly red wine intake	2.1	3.2	9.2	-1.1	-2.5	1.7	1.2	2.6	0.5	2.7	1.9	-2.9	1.3	-0.1	-3.0	-0.3	2.1	0.6	-1.7	0.0	0.1
Handedness (chirality/laterality): Left-handed	0.8	0.9	4.1	2.0	-0.0	-0.2	0.7	0.3	2.0	0.9	-0.5	1.6	-0.2	1.4	-0.0	0.1	-0.5	0.8	0.3	-0.8	-0.9
Mood swings	0.6	1.1	4.3	-0.5	1.9	0.8	0.2	-0.6	-0.1	0.6	-2.1	0.8	-0.8	-1.1	1.5	-1.3	-1.9	0.1	-0.4	-0.4	-0.4
Loneliness, isolation	0.4	0.5	2.4	-0.1	1.0	0.6	-0.8	-1.0	-0.6	-1.0	0.1	0.7	0.1	-0.4	1.6	0.5	-0.4	-0.2	0.8	0.5	0.5
Long-standing illness, disability or infirmity	0.3	0.5	2.6	0.7	0.3	1.6	-0.6	-0.4	-0.3	-0.4	0.5	1.1	0.6	-0.2	0.4	1.3	0.6	-0.2	0.3	0.6	0.5
Ever had bowel cancer screening	0.4	0.5	2.5	0.1	1.4	-0.3	-0.4	-0.7	0.5	-0.6	-1.2	0.7	-0.1	-1.0	1.6	0.4	-0.3	-0.1	0.6	0.3	0.1
Diabetes diagnosed by doctor	0.7	1.2	3.9	0.5	-1.3	0.1	-1.0	0.1	0.1	-0.3	1.8	-0.7	0.6	-0.3	-0.0	2.0	1.9	-1.2	0.2	1.6	1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.8	1.2	0.1	0.6	0.1	0.3	0.5	0.9	0.1	1.7	0.8	1.5	0.5	0.7	0.1	-0.2	0.8	0.3	0.2
Friendships satisfaction	0.4	0.5	1.8	-0.1	1.4	-0.5	-0.7	-0.7	-0.2	-0.5	0.0	1.2	0.3	0.6	0.8	0.9	-0.1	-0.4	1.0	0.5	0.5
Qualifications: nursing, teaching	0.9	1.4	5.7	-0.3	-1.2	-0.1	0.8	1.8	1.8	1.8	2.4	-0.9	1.6	0.2	-1.3	-0.1	1.5	0.4	-0.0	0.1	0.1
Commuting to job workplace: Walk	0.8	0.8	3.4	-0.3	-1.3	-0.6	0.9	1.5	0.4	0.9	1.1	-1.0	0.6	0.8	-1.8	0.3	1.0	0.5	-0.8	-0.3	-0.3
Eye problems/disorders: Cataract	0.5	0.6	4.4	0.4	0.6	2.1	0.5	0.4	-1.0	0.6	0.6	1.2	0.6	0.7	-0.5	-0.5	-0.5	0.6	-0.1	-0.4	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.7	0.1	-1.2	-0.9	-0.9	-0.1	0.3	-0.3	-0.4	-0.5	0.7	-0.4	-0.3	1.2	1.1	-1.3	0.5	1.3	1.2
Medication for cholesterol	0.3	0.5	2.0	-0.8	-1.4	-0.6	0.1	0.5	-0.2	0.5	0.2	-0.2	1.2	1.2	-1.0	0.5	0.7	0.2	0.7	0.0	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.7	-1.9	0.2	1.2	0.3	0.1	-1.4	-0.5	0.3	-1.2	0.4	-0.3	-0.7	-1.0	-0.2	0.8	-0.3	-0.5	-0.6
Back pain experienced in last month	0.8	1.2	7.3	1.0	1.8	1.3	0.1	-0.6	-0.7	0.2	0.3	2.7	-0.2	1.4	0.8	1.4	-1.3	0.3	0.5	-0.5	-0.4
Mineral and other dietary supplements	2.8	3.7	8.3	2.6	2.2	-2.1	-2.6	-2.5	0.4	-2.0	-1.3	2.6	-0.7	-0.5	2.9	1.4	0.1	-2.0	1.6	1.9	1.8
Breast cancer (self-reported)	0.4	0.5	1.6	0.2	0.3	-0.8	-0.7	-0.9	-0.9	-1.2	0.6	0.8	-0.9	-0.7	0.8	0.8	-0.3	-0.5	0.1	0.2	0.3
Asthma (self-reported)	0.3	0.6	1.8	0.5	-1.3	1.1	0.9	1.0	-0.3	1.3	-0.5	-0.8	0.4	0.9	-0.9	-0.7	0.0	0.6	-0.6	-0.5	-0.4
Osteoporosis (self-reported)	0.2	0.3	1.4	-1.2	-0.7	-0.1	0.4	0.0	-0.4	-0.6	0.7	-0.3	0.2	0.8	-0.7	-0.1	-0.6	0.3	-0.1	-0.6	-0.5
Osteoarthritis (self-reported)	0.9	1.2	6.2	0.1	0.5	2.5	1.1	1.1	2.0	1.5	1.1	1.0	0.8	0.7	0.3	0.1	0.5	1.2	0.4	-0.6	-0.8
Medication: Aspirin	0.9	1.1	3.4	0.0	0.4	0.7	1.3	0.9	1.3	0.6	0.7	-0.3	-1.1	-0.6	-0.9	-1.6	-0.4	1.5	-1.8	-1.4	-1.4
Medication: Gliclazide	2.8	3.2	10.8	1.2	-1.3	-0.2	-1.2	0.5	-0.2	-0.2	3.3	0.1	2.9	1.3	-0.6	2.0	3.2	-1.4	2.6	2.0	2.0
Illnesses of father: None of the above (group 1)	0.8	1.0	4.3	-1.0	-0.2	0.2	0.6	0.5	-0.8	0.3	0.9	-1.7	-0.8	-1.4	-1.4	-2.1	0.1	0.7	-1.1	-0.9	-0.9
Smoking status: Current	0.8	1.3	3.9	-0.8	1.5	0.2	-0.7	-1.6	-0.3	-1.4	-1.6	1.8	-1.2	-0.1	1.9	0.1	-2.0	-0.4	0.2	-0.0	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.3	-0.8	1.0	-1.2	0.7	-0.2	0.5	-0.7	1.5	-0.8	-0.5	-1.5	-0.0	-1.5	-1.0	1.5	-0.2	-1.4	-1.3
Whole body water mass	0.2	1.1	4.9	-0.8	-0.7	1.9	0.6	1.5	-0.2	2.2	0.8	-0.9	1.0	-1.0	-0.7	1.0	1.6	0.6	-0.3	0.1	0.0
Leg predicted mass (right)	0.3	1.6	7.9	-1.4	-0.1	2.2	1.2	1.4	0.0	2.8	-0.3	-1.2	-0.1	-1.9	-0.6	-0.2	0.7	1.4	-1.3	-0.7	-0.8
Arm fat mass (left)	0.6	2.6	8.2	-1.7	1.3	2.5	1.1	0.3	-0.1	1.2	-0.9	-1.1	-2.5	-2.9	0.5	-0.8	-1.6	1.5	-2.8	-1.4	-1.4
Number of self-reported non-cancer illnesses	0.4	0.6	2.7	-0.4	1.7	0.3	-0.1	-0.8	0.7	-0.7	-1.2	0.7	-0.8	-1.1	1.3	-0.1	-0.9	0.4	-0.4	-0.3	-0.5
Average weekly champagne plus white wine intake	2.3	3.2	13.7	-2.5	-2.6	-0.1	1.8	2.0	0.5	1.5	0.1	-3.7	0.7	-0.6	-2.7	-2.1	0.9	1.5	-1.3	-1.3	-1.3
Miserableness	1.6	2.8	10.9	-0.2	2.3	3.3	1.5	0.5	0.5	1.1	-0.9	-0.2	-1.9	-1.9	0.3	-2.3	-1.7	1.5	-2.3	-1.7	-1.7
Guilty feelings	2.0	3.0	7.9	-2.5	-1.0	2.4	1.7	2.5	0.9	1.9	1.8	-2.8	0.9	-0.3	-2.7	-1.4	1.2	1.3	-1.6	-0.7	-0.7
Wears glasses or contact lenses	1.5	1.7	4.6	-1.3	-1.4	1.3	1.6	1.4	0.3	0.5	0.1	-2.1	0.1	-0.9	-1.9	-0.9	-0.1	1.7	-1.6	-1.6	-1.6
Ever taken oral contraceptive pill	0.9	1.0	3.4	-0.0	1.5	0.1	-0.7	-1.4	-1.6	-1.5	-0.9	1.1	-0.5	-0.6	1.8	0.2	-1.4	-0.4	0.9	0.0	-0.0
Hearing aid user	1.1	1.2	2.8	1.4	-0.3	-1.3	-1.1	-0.9	0.4	-0.8	0.9	1.6	1.2	1.6	0.3	1.5	0.6	-0.6	1.7	0.9	0.9
Mother’s age at death	1.4	1.8	3.9	1.0	-0.8	1.6	1.8	1.9	1.6	1.1	0.1	-1.8	0.5	0.5	-2.0	-1.7	0.6	1.4	-0.8	-1.3	-1.3
Financial situation satisfaction	0.5	0.6	2.0	-0.6	-1.0	-0.4	-0.6	0.1	0.6	0.3	0.9	-1.1	1.0	-0.9	-0.6	0.2	1.4	-0.6	0.5	0.9	0.9
Tinnitus: Yes, now most or all of the time	1.0	1.1	4.1	0.8	-0.4	-0.9	-1.1	-0.2	0.8	0.2	1.2	0.1	1.5	-0.0	0.1	1.2	2.0	-0.8	1.8	1.4	1.3
Commuting to job workplace: Public transport	0.7	0.9	2.0	-0.5	-0.8	-1.0	-1.2	-0.5	0.6	-1.3	0.1	-1.1	0.9	-0.5	-0.2	0.5	1.3	-1.3	0.7	1.3	1.4
Eye problems/disorders: Glaucoma	0.4	0.4	2.8	1.7	-0.0	0.1	-0.2	-0.3	-0.3	-0.1	0.9	1.0	0.9	0.8	-0.6	0.1	0.2	0.3	0.9	-0.2	-0.2
Medication: Blood pressure	0.5	0.9	2.3	-0.1	0.7	1.3	1.4	0.6	0.4	0.6	-0.1	-0.5	-0.5	-0.3	-0.5	-1.4	-0.8	1.5	-0.8	-1.5	-1.5
Pain type(s) experienced in last month: Hip pain	0.6	0.7	4.9	-0.8	0.9	0.3	-0.8	-1.0	-2.2	-0.7	-0.8	0.7	-0.1	-0.8	0.9	0.4	-0.8	-0.8	0.1	0.5	0.6
Supplements: Fish oil (including cod liver oil)	3.8	4.9	11.6	-0.8	-2.0	2.4	3.4	3.1	0.5	2.4	1.6	-2.5	0.5	0.6	-3.4	-1.7	-0.3	2.9	-2.1	-2.7	-2.7
High cholesterol (Self-reported)	1.4	2.5	8.6	-2.9	1.3	0.4	1.0	0.5	1.9	-0.1	-0.7	-2.9	-2.1	-2.9	1.1	-1.3	-0.9	0.9	-1.7	-0.8	-1.0
Medication: Bendroflumethiazide	0.8	1.2	4.8	0.2	0.9	0.7	0.7	-0.4	-1.2	-1.3	-1.0	0.2	-2.2	-0.2	0.2	-0.2	-1.8	1.2	-1.6	-1.3	-1.3
Medication: Paracetamol	0.5	0.8	2.5	-1.2	1.6	-0.3	-0.6	-1.1	-1.3	-0.7	-0.9	0.1	-0.7	-1.2	1.0	-0.8	-1.0	-0.5	-0.1	0.1	0.1
Medication: Lisinopril	0.8	1.0	3.0	-0.3	1.6	1.5	0.8	-0.0	-1.4	-0.2	-0.1	-0.3	-0.4	-0.1	-0.7	-1.7	-1.3	0.9	-0.8	-1.4	-1.4
Medication: Atorvastatin	0.4	0.4	1.5	-0.7	1.2	1.2	0.6	0.4	1.0	0.3	1.0	-0.1	-0.7	-0.4	0.6	-0.6	-0.1	0.5	-0.4	-0.3	-0.5
Illnesses of father: High blood pressure	2.4	3.0	10.8	0.1	3.2	-0.2	0.3	-1.7	-0.4	-1.1	-2.3	2.9	-1.6	0.4	2.6	0.5	-3.3	0.9	0.4	-1.5	-1.5
Alcohol drinker status: Never	0.6	0.7	5.4	0.9	-1.2	-2.3	-0.6	-0.6	0.0	-0.1	-1.2	0.5	0.1	-0.2	0.6	1.4	-0.2	-0.7	0.1	0.6	0.6
Ever smoked	0.6	1.1	5.1	-1.7	0.1	2.3	1.3	1.0	-0.3	0.2	-0.1	0.1	-0.3	1.4	-1.0	-1.0	-1.0	0.9	-1.0	-1.2	-1.1
Basal metabolic rate	0.2	1.0	5.0	-1.0	-0.5	2.1	0.7	1.3	-0.3	2.2	0.4	-0.9	0.5	-1.2	-0.4	0.8	1.2	0.7	-0.7	-0.0	-0.1
Leg fat percentage (left)	0.3	1.2	4.5	-0.5	1.4	0.8	-0.0	-1.1	-0.6	-0.6	-1.6	0.3	-2.0	-1.3	1.5	0.1	-2.1	0.2	-1.3	-0.6	-0.5
Arm fat-free mass (left)	0.2	0.9	3.2	-0.6	-0.9	1.5	0.3	1.1	-0.5	1.8	0.6	-0.9	0.8	-0.8	-0.6	1.2	1.6	0.2	-0.3	0.4	0.4
Number of operations (self-reported)	0.5	0.7	2.2	-0.9	-0.2	1.2	1.1	1.2	0.2	0.5	1.0	-1.0	0.5	0.5	-1.5	0.0	0.7	0.9	-0.8	-0.8	-0.8
Average weekly beer plus cider intake	1.2	1.8	8.4	1.3	-1.6	-0.4	-0.4	0.5	1.8	0.8	0.7	0.9	1.9	2.9	-0.2	1.5	1.1	-0.9	1.8	1.1	1.2
Irritability	0.5	0.9	2.1	0.7	0.9	0.4	1.2	0.4	0.1	0.6	0.1	0.4	-1.0	-0.9	0.2	-1.1	-1.4	1.2	-1.2	-1.4	-1.4
Risk taking	1.0	1.4	5.1	-1.3	-0.3	0.2	-0.9	0.2	0.8	-0.3	2.3	-0.5	1.8	-0.2	0.3	1.7	1.7	-1.1	1.4	1.5	1.4
Ever had prostate specific antigen (PSA) test	2.5	2.8	9.4	0.5	-1.4	2.1	2.2	3.1	1.1	2.3	1.9	-2.3	0.6	-0.8	-2.4	-0.5	1.4	1.2	-1.9	-0.8	-0.8
Fractured/broken bones in last 5 years	0.7	0.9	3.6	0.1	-1.2	-1.7	-0.9	-0.3	-1.9	-0.7	1.2	0.3	0.7	0.6	-0.8	0.3	0.8	-1.1	0.5	0.9	0.9
Age started oral contraceptive pill	0.8	1.0	3.5	1.8	0.5	0.1	-1.0	-1.5	-1.9	-0.7	-0.6	1.5	-1.5	-1.1	0.7	0.2	-0.6	-0.2	-0.5	0.0	0.1
Diastolic blood pressure, automated reading	0.4	1.4	5.6	-0.1	0.8	-2.4	0.6	-0.6	-0.6	-0.7	-0.7	0.5	-1.7	-1.5	0.3	0.1	-1.8	1.1	-1.3	-1.5	-1.4
Ever depressed for a whole week	1.2	1.4	7.6	-0.6	-1.1	-0.0	-0.0	0.7	1.5	-0.1	2.8	-0.3	2.2	1.6	-1.2	0.8	1.4	-0.0	1.3	0.4	0.4
Unable to work because of sickness or disability	2.3	3.0	9.1	-0.2	-1.1	-0.5	-2.1	-0.8	-0.4	-1.6	1.6	-0.5	2.1	1.0	0.2	3.0	2.1	-2.4	2.1	2.4	2.5
Commuting to job workplace: Cycle	0.7	0.8	2.2	-1.5	0.7	1.0	1.0	0.7	0.4	0.0	-0.3	-1.2	-0.8	-1.2	-0.0	-0.9	-0.3	1.1	-1.2	-0.9	-1.0
Myopia	0.5	0.8	3.1	1.1	-1.3	-0.0	0.8	0.5	1.8	-0.1	0.5	-0.0	-1.1	0.2	-0.6	-0.3	-0.4	1.2	-1.4	-1.0	-0.9
Vascular/heart problems diagnosed by doctor	0.6	1.7	4.9	0.4	-1.6	-1.0	-1.2	0.4	0.1	0.8	0.7	-0.2	1.9	0.7	0.1	0.9	1.9	-2.0	1.3	2.2	2.2
Cholesterol lowering medication	0.8	1.2	6.4	-0.5	1.5	0.1	0.3	-0.2	0.1	-0.8	-0.4	-1.1	-2.2	-2.5	1.1	-0.4	-1.1	0.2	-1.5	-0.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	3.8	0.8	0.5	-0.5	-1.5	-1.6	0.5	-0.9	-0.8	1.8	0.5	-0.4	1.9	1.3	0.0	-1.5	1.2	1.2	1.2
Pain experienced in last month	0.7	1.1	5.0	-0.0	-2.2	-0.5	0.6	1.3	0.4	0.2	0.7	-2.0	0.6	1.2	-1.8	-0.5	1.5	0.3	-0.3	-0.1	-0.2
Supplements: Calcium	0.4	0.4	3.5	-0.1	-1.9	0.2	0.2	0.3	0.0	0.1	-0.9	-1.0	0.2	0.4	-1.1	-0.2	-0.3	-0.3	-0.3	-0.1	0.0
Basal cell carcinoma (self-reported)	0.9	1.0	5.9	-2.4	-0.0	0.8	0.6	0.0	0.0	0.1	0.1	-1.6	-0.8	-1.2	-0.4	-1.5	-0.8	0.9	-0.9	-1.0	-1.0
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.8	-2.0	1.1	0.4	0.5	-0.4	-1.8	-1.3	0.6	-0.1	-1.7	0.2	-0.2	-0.9	-1.9	0.7	-0.9	-1.2	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.9	-0.6	0.9	-0.6	0.4	-0.0	0.3	-0.3	-0.8	-0.3	-0.6	0.5	-1.0	-0.9	-0.4	0.9	-0.5	-0.9	-0.9
Heart disease (siblings)	0.6	0.7	2.9	-0.6	0.9	-0.2	0.2	-0.5	0.5	-0.2	-1.3	0.6	-1.7	-0.7	1.6	0.1	-1.5	0.2	-0.4	-0.4	-0.4
Alcohol drinker status: Previous	1.2	1.4	4.0	0.3	0.5	-0.2	-1.2	-0.5	-0.3	-0.9	1.7	0.8	1.8	0.4	1.1	2.0	1.0	-1.6	1.3	1.6	1.5
Pack years of smoking	0.9	1.4	4.3	-0.4	1.1	-0.7	-1.3	-1.9	-1.5	-2.1	0.3	1.7	0.4	0.4	1.2	1.8	-0.4	-0.6	1.5	0.4	0.3
Impedance of whole body	0.4	2.0	5.5	1.3	-0.7	-0.7	-1.7	-0.7	-0.1	-0.5	-0.7	1.1	1.1	1.9	1.2	1.6	0.6	-2.3	1.7	2.3	2.3
Leg fat mass (left)	0.2	0.9	2.6	-1.1	0.9	1.4	0.1	-0.5	-0.7	0.3	-1.2	-0.3	-1.6	-1.6	0.9	0.3	-1.4	0.5	-1.4	-0.5	-0.4
Arm predicted mass (left)	0.1	0.7	2.8	-0.7	-0.5	1.5	0.4	1.1	-0.5	1.7	0.6	-0.8	0.7	-0.9	-0.5	0.9	1.4	0.4	-0.3	0.2	0.1