TWAS hub - ACD

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0167	0.0117	0.0110	0.028	0.014	0.019	0.014	0.022	4.3e-05	0.0027	6.3e-04	0.0032	2.4e-04
2	TCGA	Brain Lower Grade Glioma	0.0752	0.0374	0.0077	0.014	0.003	0.033	NA	0.034	8.0e-03	0.1400	9.6e-05	NA	8.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
HDL Cholesterol	32.4	54.1	108.2	-10.4	0.0
Lung FEV1/FVC ratio	8.3	42.1	80.4	-9.0	2.0
Blood Red Count	8.0	77.2	151.3	-12.3	1.7
Medication: Seretide 50 evohaler	7.5	8.7	17.3	4.2	0.3
Ovarian Cancer	6.9	9.1	16.0	4.0	-1.5
Alcohol drinker status: Previous	6.4	7.3	12.7	-1.4	3.6
Lupus	5.1	7.7	9.5	-2.4	3.1
Hypothyroidism (self reported)	4.8	11.0	17.7	-4.2	-2.1
Schizophrenia (2014)	3.7	8.1	16.2	-4.0	0.0
Bipolar Disorder or Schizophrenia	3.6	8.7	17.4	-4.2	0.0
Medication: Blood pressure	3.5	6.7	9.2	-2.1	3.0
Schizophrenia (2018)	3.4	7.1	14.2	-3.8	0.0
Fluid intelligence score	3.3	6.8	11.3	3.4	-1.5
Peak expiratory flow (PEF)	3.3	7.6	13.5	-1.3	-3.7
Fasting Glucose	3.2	3.9	7.7	2.8	0.0
Number of treatments/medications taken	3.0	5.5	9.5	-1.2	3.1
Forced vital capacity (FVC)	3.0	11.7	13.9	3.1	-3.7
Hypothyroidism/myxoedema (self-reported)	3.0	5.9	9.4	-3.1	-1.6
Osteoporosis (self-reported)	3.0	3.7	4.1	2.0	-1.8
Verbal and Numeric Reasoning (VNR)	2.9	7.1	10.0	3.2	-2.0
Ever unenthusiastic/disinterested for a whole week	2.9	3.6	6.8	-2.6	0.6
Serious illness, injury or assault of a close relative in last 2 years	2.9	3.4	6.6	2.6	0.3
Birth weight	2.8	6.1	10.8	3.3	1.2
Chronic bronchitis/emphysema (mother)	2.8	3.3	6.4	-0.3	2.5
Medication for cholesterol	2.7	4.0	5.4	1.6	-2.3
Intelligence (Savage-Jansen 2018)	2.6	8.0	12.6	3.5	-1.8
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.0	7.7	-2.8	-0.5
Chronotype (morning person)	2.5	5.8	7.7	2.8	-2.0
Mineral and other dietary supplements	2.5	3.4	4.9	-1.4	2.2
Heart attack/myocardial infarction (self-reported)	2.5	3.3	3.7	-1.9	1.7
Heart attack	2.4	3.1	3.5	-1.6	1.9
Time employed in main current job	2.4	2.7	2.8	-1.6	-1.7
Number of full sisters	2.4	2.9	4.4	1.2	2.1
Primary Biliary Cirrhosis	2.3	3.3	6.5	-2.5	0.0
Forced vital capacity (FVC), Best measure	2.3	8.6	10.5	2.6	-3.2
Chest pain or discomfort	2.3	3.3	5.0	2.2	-1.3
Supplements: Fish oil (including cod liver oil)	2.3	3.0	5.1	0.9	-2.3
Father’s age at death	2.2	2.9	3.1	-1.7	-1.8
Commuting to job workplace: Public transport	2.2	2.6	3.8	1.2	1.9
Myopia	2.2	3.2	6.4	-2.5	-0.3
Hair/balding pattern: Pattern 3	2.1	3.1	4.6	2.1	-1.2
Pulse wave peak to peak time	2.1	2.4	4.7	2.2	0.4
Supplements: Vitamin C	2.1	2.5	2.8	-1.7	1.5
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	5.4	-2.3	0.4
Average weekly spirits intake	2.0	2.5	5.0	2.2	0.2
Medication: Atenolol	2.0	2.4	2.7	-1.6	1.5
Falls in the last year	2.0	2.6	5.2	2.3	0.3
Number of full brothers	2.0	2.5	4.5	2.1	0.7
Ever depressed for a whole week	2.0	2.4	4.6	-2.1	0.5
Forced expiratory volume in 1-second (FEV1)	1.9	6.3	12.6	-0.0	-3.6
Happiness	1.9	2.3	3.5	1.0	1.9
Emphysema/chronic bronchitis	1.9	2.2	3.8	1.9	-0.8
Prostate Cancer	1.8	2.5	5.0	2.2	0.1
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	4.0	-2.0	-0.4
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.3	-0.0	2.1
Had other major operations	1.8	2.2	3.0	-1.7	1.2
Alcohol intake frequency.	1.8	4.2	4.6	-2.1	2.0
Ever had bowel cancer screening	1.8	2.1	4.1	0.1	2.0
Medication: Aspirin	1.8	2.3	2.9	-1.3	1.7
Mother’s age at death	1.8	2.2	3.1	-1.2	-1.8
Illnesses of father: High blood pressure	1.8	2.2	4.2	-2.1	0.4
Irritability	1.8	3.0	4.4	-2.1	1.3
Basal cell carcinoma (self-reported)	1.8	2.1	3.2	1.8	-1.0
Worry (Nagel 2018)	1.7	3.6	5.2	-2.3	-1.4
Qualifications: CSEs or equivalent	1.7	2.3	4.4	-2.1	-0.4
Pulse wave Arterial Stiffness index	1.7	2.0	3.6	-1.9	-0.6
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	5.3	0.1	-2.3
Blood clot in the leg (DVT)	1.7	2.2	4.3	-2.1	0.3
Mood swings	1.7	3.1	5.2	-2.3	-1.0
Average weekly champagne plus white wine intake	1.7	2.4	3.0	-1.3	1.7
Taking other prescription medications	1.6	2.4	3.7	-1.1	1.9
Stomach or abdominal pain in last month	1.6	2.0	3.8	-2.0	0.4
Nervous feelings	1.6	3.0	3.9	-2.0	-1.5
Prospective memory result	1.6	2.0	3.8	-2.0	0.3
Medication: Ibuprofen	1.6	1.9	3.1	-0.9	1.8
Risk taking	1.6	2.3	3.9	0.8	-2.0
Cholesterol lowering medication	1.6	2.3	4.0	-0.8	2.0
Supplements: Zinc	1.5	1.7	3.3	-1.8	-0.1
Pack years adult smoking proportion	1.5	2.3	2.6	1.6	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	9.2	0.3	-3.0
Medication for pain relief, constipation, heartburn	1.5	2.6	5.2	-0.1	-2.3
Heart disease (mother)	1.5	1.8	3.4	-0.5	1.9
Had major operations	1.5	1.7	2.9	1.7	-0.7
Allergy or Eczema	1.4	3.8	7.0	2.6	-0.8
Lung FVC	1.4	7.4	12.9	3.6	-1.4
Asthma	1.4	2.7	2.9	1.6	1.7
Depression (self-reported)	1.4	1.7	3.2	-0.5	-1.8
Illnesses of mother	1.4	1.7	1.9	1.2	-1.4
Suffer from ‘nerves’	1.4	2.2	4.4	-2.1	-0.1
Asthma (self-reported)	1.4	2.8	3.3	1.8	1.5
Number of operations (self-reported)	1.4	2.1	2.6	-1.6	1.3
Breast Cancer	1.3	3.2	6.2	2.5	0.4
Respiratory disease	1.3	2.8	5.2	2.3	0.7
Supplements: Glucosamine	1.3	1.7	2.4	1.5	-1.0
Eye problems/disorders: None of the above	1.3	1.5	2.9	1.7	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.2	0.9	1.5
Wears glasses or contact lenses	1.3	1.5	2.7	-0.5	1.7
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.3	-1.8	-0.1
Medication: Lisinopril	1.3	1.7	3.3	1.8	-0.3
Alcohol drinker status: Never	1.3	1.6	2.9	-0.6	-1.7
Ever smoked	1.3	2.3	3.2	-1.8	1.2
Bipolar Disorder (2018)	1.2	1.9	3.9	-2.0	0.0
Neuroticism (Nagel 2018)	1.2	2.8	4.4	-2.1	-1.1
Alzheimer’s Disease (including proxy)	1.2	1.8	3.5	-0.3	-1.9
Waist Hip Ratio (WHR)	1.2	5.5	9.1	3.0	1.4
Multivitamins +/- minerals	1.2	1.6	2.1	-1.4	-1.0
Medication: Levothyroxine sodium	1.2	2.1	3.3	-1.8	-0.9
Number of incorrect matches in round	1.2	2.1	2.2	-1.4	1.5
Hair/balding pattern: Pattern 2	1.2	1.5	2.3	-1.5	-0.8
Hair/balding pattern: Pattern 4	1.2	2.9	5.7	2.4	-0.1
Neck or shoulder pain in last month	1.2	1.7	2.6	-1.6	0.9
Medication: Aspirin	1.2	1.6	2.6	-0.8	1.6
Average weekly red wine intake	1.2	1.8	3.1	1.7	-0.8
Eye problems/disorders: Cataract	1.2	1.4	2.7	-1.6	0.3
Hearing aid user	1.2	1.3	2.4	1.6	-0.5
Pack years of smoking	1.2	1.8	2.1	1.5	1.2
Depression (Nagel 2018)	1.1	1.7	2.9	-1.7	0.8
Coronary Artery Disease (CAD)	1.1	1.4	2.7	1.6	0.0
Hearing difficulty/problems: Yes	1.1	1.7	2.0	1.4	1.2
Sitting height	1.1	8.0	15.4	-0.8	-3.9
Neuroticism score	1.1	2.3	2.7	-1.6	-1.4
Trunk fat-free mass	1.1	6.5	9.9	1.8	-3.1
Trunk predicted mass	1.1	6.1	9.0	1.8	-3.0
Qualifications: College or University degree	1.1	3.5	5.1	2.3	-1.3
Mean time to correctly identify matches	1.1	2.1	3.2	-1.0	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	1.5	1.1	1.2
Osteoarthritis (self-reported)	1.1	1.4	2.6	-1.6	-0.4
Miserableness	1.1	1.9	3.8	-0.0	-1.9
Ulcerative Colitis (UC)	1.0	2.0	2.2	-1.3	1.5
Sensitivity / hurt feelings	1.0	1.7	2.0	-1.2	-1.4
Diabetes (mother)	1.0	1.3	2.3	-1.5	0.5
High blood pressure (mother)	1.0	1.4	1.6	-1.3	1.1
Standing height	1.0	9.6	16.7	1.6	-4.1
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	1.7	-1.3	0.9
Shortness of breath walking on level ground	1.0	1.2	2.1	1.5	0.5
Medication: Blood pressure	1.0	1.8	3.6	1.9	-0.2
Illnesses of siblings: Diabetes	1.0	1.2	2.0	0.7	1.4
Smoking status: Previous	1.0	1.5	3.0	-1.7	0.3
Medication: Gliclazide	1.0	1.2	1.7	-0.8	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	3.1	-1.1	-1.8
Schizophrenia vs Biploar Disorder	0.9	1.2	2.5	-1.6	0.0
Heel T-Score	0.9	6.9	10.4	-3.2	1.9
Neuroticism	0.9	2.3	4.1	-2.0	-0.7
Hand grip strength (left)	0.9	2.3	4.6	0.0	-2.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.0	-1.4	-0.0
Alcohol usually taken with meals	0.9	1.5	2.5	-1.6	0.7
Financial difficulties in last 2 years	0.9	1.1	2.3	0.1	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	2.1	-0.4	1.4
Medication: Lansoprazole	0.9	1.0	1.6	-0.6	1.3
Ever highly irritable/argumentative for 2 days	0.9	1.0	1.8	-1.4	0.5
Arm fat-free mass (right)	0.9	4.6	7.6	1.2	-2.8
Leg pain on walking	0.9	1.1	1.5	1.2	0.8
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.0	0.4	-1.4
Pain experienced in last month	0.9	1.5	2.6	1.6	-0.5
Alzheimer’s Disease (in mother)	0.8	0.9	1.7	-0.5	-1.3
Hand grip strength (right)	0.8	2.1	3.7	-0.7	-1.9
Loud music exposure frequency	0.8	0.9	1.7	-0.2	-1.3
Migraine (self-reported)	0.8	1.0	2.0	-1.4	-0.2
Whole body fat-free mass	0.8	4.8	8.1	1.2	-2.8
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.3	1.1	0.8
Back pain experienced in last month	0.8	1.1	1.7	-1.3	0.8
High cholesterol (Self-reported)	0.8	1.4	1.7	-1.3	1.0
Crohns Disease (2017)	0.7	1.6	1.9	1.2	-1.4
Height	0.7	14.2	24.3	2.0	-4.9
Medication for hormone replacement therapy	0.7	0.8	1.4	-0.4	1.2
Medication: Co-codamol	0.7	0.8	1.4	-1.2	0.4
Diabetes (father)	0.7	0.9	1.6	-1.2	-0.5
Leg fat-free mass (left)	0.7	3.6	6.1	1.0	-2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.8	-1.3	0.0
Leg predicted mass (left)	0.7	3.5	6.0	1.0	-2.5
Medication: Cholesterol lowering	0.7	1.1	2.0	-1.4	-0.5
Arm predicted mass (right)	0.7	3.5	5.7	1.1	-2.4
Whole body water mass	0.7	4.2	7.0	1.2	-2.6
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	0.2	1.3
Basal metabolic rate	0.7	4.0	6.4	1.3	-2.5
Alzheimer’s Disease (in father)	0.6	0.7	1.1	-0.5	-1.1
Reaction Time	0.6	1.1	1.8	-0.7	1.3
Neuroticism (2016)	0.6	0.9	1.7	-1.3	0.0
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.4	-1.2	0.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.4	0.0	1.2
Vitamin and mineral supplements	0.6	0.8	1.2	1.1	-0.5
Current tobacco smoking	0.6	1.0	2.1	1.4	0.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.5	1.2	0.2
Medication: Simvastatin	0.6	0.8	1.5	-1.2	-0.4
Qualifications: A levels/AS levels or equivalent	0.6	1.4	1.8	1.4	-1.0
Lung cancer (father)	0.6	0.7	1.1	-1.1	-0.5
Tense / ‘highly strung’	0.6	1.0	1.8	-1.4	0.3
Pulse wave reflection index	0.6	0.7	1.2	-1.1	-0.4
Wheeze or whistling in the chest in last year	0.6	1.1	2.0	1.4	0.5
Number of children fathered	0.6	0.7	1.0	1.0	-0.6
Age at first live birth	0.6	1.0	1.9	0.4	-1.4
Qualifications: nursing, teaching	0.6	0.9	1.7	-1.3	-0.4
Smoking status: Current	0.6	1.0	2.0	1.4	0.3
Average weekly beer plus cider intake	0.6	0.9	1.4	1.2	-0.6
Depressed Affect (Nagel 2018)	0.5	1.0	1.1	-1.1	-0.9
Age at First Birth	0.5	0.7	1.3	1.2	0.0
Townsend deprivation index at recruitment	0.5	0.7	1.1	1.0	0.5
Relative age voice broke	0.5	0.8	1.6	0.0	1.3
Serious illness, injury or assault to yourself	0.5	0.6	0.6	0.8	-0.8
Waist circumference	0.5	2.0	3.0	1.7	1.0
Diabetes (self-reported)	0.5	0.7	1.5	0.0	-1.2
Worrier / anxious feelings	0.5	0.9	1.5	-0.6	-1.2
Noisy workplace	0.5	0.6	0.7	-0.8	0.7
Length of working week for main job	0.5	0.6	1.1	0.2	1.0
Medication: Paracetamol	0.5	0.9	0.9	1.0	0.9
Leg fat-free mass (right)	0.5	2.8	5.1	0.6	-2.3
Loneliness, isolation	0.5	0.7	0.8	-0.9	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.1	0.1	-1.0
Leg predicted mass (right)	0.5	2.7	4.9	0.6	-2.2
Medication: Bendroflumethiazide	0.5	0.8	1.4	0.3	1.2
Medication: Paracetamol	0.5	0.8	1.2	0.6	1.1
Arm fat-free mass (left)	0.5	2.4	3.3	1.2	-1.8
Unable to work because of sickness or disability	0.5	0.6	0.9	0.6	0.9
Commuting to job workplace: Cycle	0.5	0.6	1.1	-1.1	0.2
Arm predicted mass (left)	0.5	2.6	4.2	1.0	-2.0
Rheumatoid Arthritis	0.4	0.6	1.2	1.1	0.0
Triglycerides	0.4	0.7	1.4	1.2	0.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.0	1.0	0.0
Blood White Count	0.4	2.7	5.1	2.3	0.6
Hair Pigment	0.4	10.9	19.9	-4.5	1.4
Ever had hysterectomy (womb removed)	0.4	0.5	0.9	-0.3	-0.9
Past tobacco smoking	0.4	0.8	1.3	1.1	-0.5
Medication: Ramipril	0.4	0.5	1.0	0.3	1.0
Impedance of arm (right)	0.4	1.8	2.5	-1.6	1.1
Arm fat percentage (right)	0.4	1.5	2.6	-0.6	1.6
Alcohol intake versus 10 years previously	0.4	0.6	0.7	0.9	-0.6
Worry too long after embarrassment	0.4	0.7	1.5	-1.2	-0.0
Family relationship satisfaction	0.4	0.5	0.7	0.8	0.6
Knee pain experienced in last month	0.4	0.7	0.9	-1.0	0.7
Illnesses of father: None of the above (group 1)	0.4	0.5	0.7	0.8	0.5
Number of self-reported non-cancer illnesses	0.4	0.7	1.3	-0.3	1.1
Angina	0.3	0.4	0.7	0.4	-0.8
High blood pressure	0.3	0.9	1.8	-0.0	1.3
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.4	1.2	-0.2
Mouth/teeth dental problems: Dentures	0.3	0.4	0.8	0.3	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.7	-0.8	0.6
Birth weight of first child	0.3	0.5	0.9	1.0	0.2
Glaucoma (self-reported)	0.3	0.3	0.5	0.4	-0.7
Angina (self-reported)	0.3	0.4	0.5	0.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.5	-0.4	0.7
Pulse rate, automated reading	0.3	0.8	1.4	-0.5	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.8	0.9	-0.1
Friendships satisfaction	0.3	0.3	0.4	0.6	0.6
Guilty feelings	0.3	0.4	0.8	-0.0	-0.9
Leg fat percentage (left)	0.3	1.0	1.9	-0.4	1.4
Fractured/broken bones in last 5 years	0.3	0.4	0.7	0.1	-0.8
Diastolic blood pressure, automated reading	0.3	1.0	1.7	-1.3	-0.6
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.7	0.4	-1.3
Crohns Disease (2012)	0.2	0.3	0.6	0.8	0.0
Blood Eosinophil Count	0.2	1.9	3.0	-0.9	1.7
Blood Platelet Count	0.2	1.8	2.3	1.5	1.1
Smoking Status	0.2	0.5	0.6	-0.7	-0.7
Relative age of first facial hair	0.2	0.3	0.4	0.6	0.6
Systolic blood pressure, automated reading	0.2	0.6	1.0	0.4	-1.0
Medication: Metformin	0.2	0.3	0.5	0.2	0.7
Trunk fat percentage	0.2	0.6	1.0	-1.0	0.6
Fed-up feelings	0.2	0.4	0.5	-0.6	-0.7
Age when periods started (menarche)	0.2	0.5	0.8	-0.9	0.4
Impedance of leg (left)	0.2	0.9	1.0	-1.0	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.4	-0.7	-0.6
Illnesses of siblings	0.2	0.3	0.4	-0.4	-0.6
Weight	0.2	0.9	1.1	0.8	-1.1
Pulse rate	0.2	0.4	0.6	-0.8	-0.4
Impedance of arm (left)	0.2	1.1	2.1	-1.5	0.4
Headache pain in last month	0.2	0.3	0.3	-0.5	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.5	-0.3	0.7
Gout (self-reported)	0.2	0.2	0.4	0.1	0.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	0.7	-0.0
Exposure to tobacco smoke outside home	0.2	0.3	0.6	-0.3	0.7
Comparative body size at age 10	0.2	0.6	0.7	-0.8	0.8
Overall health rating	0.2	0.5	0.9	-0.2	0.9
Age at last live birth	0.2	0.2	0.4	-0.2	-0.6
Hypertension (Self-reported)	0.2	0.7	1.3	-0.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.4	0.6	-0.7
Arm fat percentage (left)	0.2	0.7	1.1	-0.5	1.0
Diabetes diagnosed by doctor	0.2	0.3	0.5	-0.3	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	0.2	0.7
Ever taken oral contraceptive pill	0.2	0.2	0.4	0.2	0.7
Financial situation satisfaction	0.2	0.3	0.3	0.5	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.3	-0.4	-0.6
Supplements: Calcium	0.2	0.2	0.3	0.2	0.6
Impedance of whole body	0.2	1.0	1.7	-1.3	0.6
Mean Putamen Volume	0.1	0.1	0.2	0.4	0.0
HbA1C	0.1	0.1	0.2	0.4	0.0
LDL Cholesterol	0.1	0.2	0.5	-0.7	0.0
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.6	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	-0.0	0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	0.0	0.5
Severe depression (siblings)	0.1	0.1	0.1	-0.1	0.4
Average weekly fortified wine intake	0.1	0.1	0.1	0.3	-0.3
Maternal smoking around birth	0.1	0.1	0.2	0.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.5	-0.7	0.4
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.5	0.0
Body mass index (BMI)	0.1	0.3	0.5	-0.0	0.7
Hearing difficulty/problems with background noise	0.1	0.1	0.1	-0.3	0.3
Had menopause	0.1	0.2	0.2	-0.4	0.5
Qualifications: None of the above	0.1	0.3	0.5	-0.0	0.7
Allergy	0.1	0.2	0.3	-0.6	0.1
Pain all over the body in last month	0.1	0.1	0.2	-0.4	0.0
Hip circumference	0.1	0.3	0.4	0.5	-0.6
Number of live births	0.1	0.1	0.2	0.1	0.4
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.3	0.2
Breastfed as a baby	0.1	0.2	0.3	0.2	0.5
Medication: Amlodipine	0.1	0.2	0.3	-0.3	0.5
High blood pressure (siblings)	0.1	0.2	0.3	0.1	0.6
Body fat percentage	0.1	0.6	0.7	-0.7	0.8
Leg fat percentage (right)	0.1	0.5	0.9	0.2	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.3	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.3	0.2
Medication: Allopurinol	0.1	0.2	0.4	0.6	-0.0
Comparative height size at age 10	0.1	0.4	0.5	0.5	-0.7
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	0.5	-0.1
Commuting to job workplace: Walk	0.1	0.1	0.2	0.3	-0.5
Breast cancer (self-reported)	0.1	0.1	0.2	-0.5	0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.3	0.1
Medication: Atorvastatin	0.1	0.1	0.3	0.1	0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.3	-0.2	0.5
Heart disease (siblings)	0.1	0.1	0.1	-0.3	-0.2
Irritable Bowel Disease (IBD)	0.0	0.1	0.2	0.2	0.4
Major Depression (MDD)	0.0	0.0	0.0	0.1	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	-0.2	0.0
Ulcerative Colitis	0.0	0.1	0.1	-0.3	0.0
BMI	0.0	0.0	0.1	-0.3	0.0
Systolic Blood Pressure	0.0	0.1	0.1	0.3	-0.1
Cardiovascular Disease	0.0	0.0	0.1	-0.3	0.1
Tanning	0.0	0.5	0.6	-0.6	-0.8
Impedance of leg (right)	0.0	0.0	0.0	-0.1	0.2
Trunk fat mass	0.0	0.1	0.1	-0.2	-0.3
Mouth/teeth dental problems	0.0	0.0	0.0	-0.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	0.1	-0.1
Arm fat mass (right)	0.0	0.1	0.2	-0.2	0.4
Health satisfaction	0.0	0.0	0.0	0.2	-0.2
Medication: Omeprazole	0.0	0.0	0.0	-0.1	0.1
Whole body fat mass	0.0	0.0	0.1	-0.2	0.1
Leg fat mass (right)	0.0	0.1	0.1	0.3	0.1
Illnesses of father: Heart disease	0.0	0.0	0.0	0.1	-0.2
Long-standing illness, disability or infirmity	0.0	0.0	0.0	-0.1	0.0
Arm fat mass (left)	0.0	0.0	0.1	-0.2	0.2
Age started oral contraceptive pill	0.0	0.0	0.0	0.1	0.2
Leg fat mass (left)	0.0	0.0	0.1	-0.1	0.3

Hub : Genes

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Trait associations