Hub : Genes

ACOX3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1410 0.0360 1.6e-05 0.028 0.033 0.059 0.061 0.064 2.1e-04 5.9e-05 9.5e-08 5.7e-08 2.8e-08
2 GTEx Adipose Subcutaneous 0.2190 0.0490 3.9e-06 0.130 NA 0.097 NA 0.122 8.8e-11 NA 2.3e-08 NA 3.9e-10
3 GTEx Adipose Visceral Omentum 0.2870 0.0670 6.3e-05 0.027 NA 0.053 NA 0.076 1.5e-02 NA 1.0e-03 NA 9.1e-05
4 GTEx Adrenal Gland 0.1504 0.0603 7.9e-03 0.120 NA 0.127 NA 0.128 4.5e-05 NA 2.8e-05 NA 2.5e-05
5 GTEx Artery Aorta 0.1480 0.0540 6.0e-03 0.034 NA 0.041 NA 0.059 5.3e-03 NA 2.5e-03 NA 3.4e-04
6 GTEx Artery Tibial 0.2803 0.0517 1.1e-08 0.163 NA 0.155 NA 0.168 8.4e-13 NA 3.6e-12 NA 3.9e-13
7 GTEx Brain Nucleus accumbens basal ganglia 0.4160 0.1090 1.7e-03 0.006 NA 0.089 NA -0.011 2.1e-01 NA 2.3e-03 NA 8.7e-01
8 GTEx Breast Mammary Tissue 0.1880 0.0680 4.6e-03 -0.001 NA 0.044 NA 0.059 3.6e-01 NA 2.6e-03 NA 5.7e-04
9 GTEx Breast Mammary Tissue (Male) 0.2624 0.1613 1.0e-01 -0.013 NA 0.019 NA 0.000 8.9e-01 NA 1.2e-01 NA 3.2e-01
10 GTEx Breast Mammary Tissue (Female) 0.0818 0.0950 2.5e-01 0.010 NA -0.010 NA 0.004 1.6e-01 NA 8.9e-01 NA 2.4e-01
11 GTEx Cells EBV-transformed lymphocytes 0.4570 0.1330 6.2e-03 -0.005 NA -0.009 NA -0.008 4.8e-01 NA 9.0e-01 NA 7.7e-01
12 GTEx Cells Transformed fibroblasts 0.2540 0.0510 5.5e-09 0.141 NA 0.115 NA 0.138 9.5e-11 NA 5.8e-09 NA 1.6e-10
13 GTEx Lung 0.1250 0.0384 1.0e-04 0.035 NA 0.050 NA 0.053 1.1e-03 NA 9.6e-05 NA 6.2e-05
14 GTEx Nerve Tibial 0.3551 0.0630 6.1e-09 0.170 NA 0.140 NA 0.167 3.9e-12 NA 4.2e-10 NA 6.6e-12
15 GTEx Testis 0.2400 0.0610 1.1e-04 0.070 NA 0.107 NA 0.110 4.9e-04 NA 1.8e-05 NA 1.3e-05
16 GTEx Thyroid 0.2600 0.0580 4.1e-07 0.109 NA 0.077 NA 0.109 1.1e-08 NA 1.7e-06 NA 1.2e-08
17 NTR Blood 0.0337 0.0115 4.5e-04 0.001 0.007 0.003 0.007 0.002 1.1e-01 2.4e-03 2.5e-02 2.0e-03 6.5e-02
18 ROSMAP Brain Pre-frontal Cortex 0.0835 0.0261 2.5e-04 0.025 0.033 0.066 0.054 0.060 2.7e-04 4.1e-05 6.3e-09 1.4e-07 3.0e-08
19 YFS Blood 0.2301 0.0258 0.0e+00 0.198 0.232 0.257 0.241 0.246 1.0e-62 1.7e-74 1.5e-83 6.0e-78 1.1e-79
20 TCGA Head and Neck Squamous Cell Carcinoma 0.0369 0.0204 5.4e-03 0.008 0.011 0.005 NA 0.011 3.4e-02 1.9e-02 8.2e-02 NA 1.7e-02
21 TCGA Kidney Renal Clear Cell Carcinoma 0.0619 0.0291 1.2e-03 0.008 0.024 0.022 NA 0.017 3.8e-02 9.2e-04 1.4e-03 NA 4.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.2 0.4 1.7 1.3 -0.0 -0.2 1.2 0.3 -0.4 0.0 0.5 0.6 0.4 0.3 0.9 0.9 0.3 -0.6 -0.2 0.3 -0.6 0.1 1.2 0.2
Bipolar Disorder or Schizophrenia 0.4 1.1 3.5 1.2 0.7 0.6 1.8 0.7 0.7 0.0 1.3 1.9 0.7 0.2 1.8 1.9 0.8 1.0 0.3 -0.4 -0.4 -0.4 0.2 1.2
Depressed Affect (Nagel 2018) 0.4 0.8 2.6 1.3 0.8 1.0 0.1 1.1 1.3 0.0 -1.1 -0.3 -0.3 -1.0 0.3 0.8 0.5 0.3 -0.0 -0.7 1.6 -0.1 -1.4 1.6
Depression (Nagel 2018) 0.9 1.4 5.2 -1.3 -0.2 1.8 -0.6 0.5 0.3 0.0 0.5 0.8 2.3 1.5 -0.2 -0.6 0.3 0.7 -0.3 -1.5 1.4 0.7 2.3 2.2
Intelligence (Savage-Jansen 2018) 0.6 1.9 6.6 1.0 -0.9 -1.7 1.8 -1.0 -1.2 0.0 -1.1 -0.3 -1.4 -2.3 1.9 1.3 -1.3 -0.5 -0.3 -1.2 -2.6 -0.6 -1.3 -1.6
Neuroticism (Nagel 2018) 0.2 0.4 1.1 1.0 0.8 0.9 0.4 1.0 1.1 0.0 0.2 0.1 0.1 -0.6 0.3 0.9 0.6 0.6 0.3 -0.7 0.2 -0.7 -0.9 0.8
Schizophrenia (2018) 0.6 1.2 4.4 0.6 0.9 0.9 1.4 0.6 1.1 0.0 1.4 2.1 0.5 -0.0 1.5 1.6 0.8 1.8 0.6 -0.7 -0.1 -0.7 -0.7 1.4
Schizophrenia vs Biploar Disorder 0.8 1.0 4.1 -0.6 1.4 0.6 0.7 0.7 0.9 0.0 0.4 0.1 0.0 -1.6 0.9 1.1 0.7 2.0 1.4 -1.0 -0.4 -2.0 -1.0 0.2
Worry (Nagel 2018) 0.3 0.5 2.4 -0.1 0.6 1.6 0.7 0.2 0.7 0.0 0.6 -0.1 1.0 -0.4 0.5 1.1 0.3 1.4 0.5 -1.2 -0.3 -0.7 -0.4 0.3
Alzheimer’s Disease (in mother) 1.2 1.4 8.6 2.9 0.4 -1.0 1.4 0.7 -0.1 0.0 -0.8 0.7 -1.4 -0.4 0.8 1.3 0.4 -0.8 0.7 -0.7 -1.7 -1.7 -1.5 -0.7
Alzheimer’s Disease (in father) 0.3 0.3 1.6 -0.5 0.5 0.2 -0.1 0.9 0.1 0.0 0.9 0.7 0.2 1.3 0.1 0.0 0.5 0.2 0.4 -0.9 0.3 -0.2 0.9 0.1
Alzheimer’s Disease (including proxy) 0.5 0.8 2.3 1.4 0.8 0.2 1.5 1.3 0.2 0.0 0.2 0.9 -0.1 0.8 1.1 1.5 0.9 0.2 0.8 -1.3 -0.5 -1.2 -0.0 0.1
Crohns Disease (2017) 0.2 0.5 2.3 0.7 0.3 -1.2 0.1 0.1 -0.1 0.0 -0.3 -0.3 -1.3 -1.5 -0.1 0.1 -0.0 -0.2 0.5 0.7 -0.8 -0.6 -1.5 -0.7
Irritable Bowel Disease (IBD) 0.5 1.2 3.7 0.4 1.6 -0.0 0.7 1.9 1.5 0.0 1.0 1.8 -0.4 -0.5 0.2 0.8 1.5 0.6 1.8 -0.5 -0.7 -1.4 -0.6 0.7
Ulcerative Colitis (UC) 1.1 2.1 7.5 0.6 1.9 0.9 1.1 2.4 2.1 0.0 1.6 2.7 0.4 0.2 0.6 1.3 2.1 0.7 2.1 -1.2 -0.3 -1.4 0.3 1.6
Major Depression (MDD) 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 -0.4
Reaction Time 0.8 1.5 4.5 0.3 1.2 1.6 0.3 2.1 2.0 0.0 -0.2 1.9 0.7 1.2 0.1 0.6 2.0 0.3 1.7 -0.7 1.1 -0.5 0.6 1.9
Verbal and Numeric Reasoning (VNR) 0.3 0.8 4.9 0.7 -0.6 -1.1 1.3 -0.6 -0.8 0.0 -1.0 -0.7 -0.4 -0.9 1.3 0.9 -0.7 0.2 -0.0 -0.9 -2.2 -0.3 -0.4 -1.0
Breast Cancer 1.1 2.6 9.1 -0.2 -2.4 -0.9 0.9 -2.7 -2.6 0.0 -0.5 -1.1 -0.7 -1.2 1.1 -0.5 -2.5 -1.9 -2.0 0.6 -2.5 0.5 0.0 -3.0
Ovarian Cancer 0.2 0.2 1.5 -1.2 -0.2 -0.1 0.2 -0.5 -0.2 0.0 0.1 -0.0 -0.4 -0.8 0.3 0.1 -0.4 -0.3 -0.7 -0.4 -0.3 0.6 0.1 -0.2
Prostate Cancer 0.3 0.5 3.3 0.4 0.2 -0.6 -0.7 0.8 0.1 0.0 -0.8 0.6 -0.8 0.4 -0.9 -0.4 -0.3 0.2 0.8 -0.9 0.5 -0.5 -1.8 0.7
Age at First Birth 0.1 0.1 1.2 0.0 -0.1 0.2 0.2 -0.5 -0.3 0.0 0.5 -0.1 0.1 0.4 0.2 -0.0 -0.2 0.3 0.0 1.1 -0.5 -0.0 0.3 -0.6
Bipolar Disorder (2011) 0.2 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 -1.9
Body Mass Index (BMI) (2010) 0.8 1.1 3.4 -0.8 0.5 1.7 1.0 -0.1 0.3 0.0 1.8 -0.6 1.6 1.3 1.0 1.1 0.5 1.4 -0.0 -0.7 -1.1 -0.7 1.8 0.1
Coronary Artery Disease (CAD) 0.8 1.0 4.7 1.2 -1.3 -1.0 0.8 -1.3 -1.5 0.0 0.7 0.5 0.0 0.5 0.5 -0.2 -1.5 -0.1 -1.5 0.8 -2.2 -0.2 0.0 -1.2
Crohns Disease (2012) 0.5 0.8 2.5 -0.2 -0.2 -0.3 -1.6 -0.7 -0.5 0.0 -1.2 -1.1 -0.6 -0.5 -1.5 -1.6 -0.7 0.0 -0.3 1.5 1.1 0.6 -1.2 -0.6
Mean Putamen Volume 0.7 0.8 3.6 1.8 -0.8 -1.2 -0.5 -0.3 -0.7 0.0 -0.1 0.3 -0.7 -0.5 -0.8 -0.5 -0.2 -1.9 -0.3 1.6 -0.0 0.2 0.5 -1.1
Fasting Glucose 0.6 0.7 3.9 -1.1 -0.3 1.0 0.3 0.3 -0.0 0.0 0.4 0.8 2.0 1.3 0.2 -0.4 -0.1 0.8 -0.2 -0.4 -0.0 1.1 1.7 0.8
HbA1C 1.0 1.2 3.2 0.0 -1.2 -1.5 1.1 -1.3 -0.9 0.0 -1.8 -1.7 -1.0 -0.9 0.9 -0.2 -1.1 -1.1 -1.1 1.7 -0.5 1.0 -0.6 -0.7
HDL Cholesterol 1.1 1.9 5.1 -1.6 1.9 1.2 0.3 1.7 1.8 0.0 1.5 1.5 1.5 -0.6 0.5 0.2 1.7 2.0 1.6 -1.7 0.4 -0.8 0.7 2.3
LDL Cholesterol 2.2 3.4 12.1 1.5 -1.9 -1.9 -1.2 -2.4 -1.7 0.0 -2.1 -3.5 -1.5 -0.8 -1.1 -1.5 -1.9 -2.7 -1.6 3.1 0.4 1.7 -0.1 -1.9
Lupus 0.6 0.8 6.7 0.2 -0.1 1.1 0.8 0.6 0.4 0.0 2.6 2.0 -0.0 0.1 0.3 0.8 0.6 -0.6 0.8 -0.5 -0.0 -0.5 1.2 0.6
Neuroticism (2016) 0.7 1.0 4.7 -1.2 -0.0 0.1 -1.3 0.5 0.6 0.0 0.4 0.5 0.1 1.7 -1.5 -1.3 -0.1 0.2 -0.5 -0.2 2.2 1.2 -0.0 1.6
Primary Biliary Cirrhosis 0.8 1.1 4.1 1.2 1.7 1.4 0.2 2.0 1.6 0.0 -1.0 0.0 -0.3 1.2 -0.2 0.5 1.7 0.2 1.5 -0.6 -0.2 -1.1 -0.4 0.8
Rheumatoid Arthritis 0.2 0.3 1.7 0.5 -0.6 -0.3 -0.3 0.6 -0.4 0.0 0.0 0.1 -0.5 -0.7 -0.3 -0.5 -0.6 -0.4 -0.3 -1.3 0.4 0.5 -0.3 0.5
Schizophrenia (2014) 0.5 1.0 3.5 1.1 0.9 0.8 1.9 0.6 0.9 0.0 0.7 1.0 0.7 -0.0 1.8 1.6 0.7 1.6 0.4 -0.6 -0.4 -0.9 -0.2 1.1
Triglycerides 0.3 0.5 1.8 0.8 -0.7 -0.3 0.3 -0.8 -0.8 0.0 -0.7 -0.7 -1.3 -0.9 0.3 0.2 -0.6 -1.3 -0.4 0.5 -0.2 0.5 -0.1 -1.1
Type 2 Diabetes (T2D) (2012) 1.0 1.2 5.2 1.2 1.2 -0.1 1.6 0.7 0.6 0.0 -0.6 -0.4 -0.9 -1.0 1.1 1.2 1.1 -0.2 1.0 0.3 -2.3 -2.0 -0.4 -1.2
Ulcerative Colitis 0.7 1.0 3.3 0.4 1.7 1.0 0.6 1.7 1.8 0.0 -0.2 0.4 0.3 0.0 0.2 0.9 1.6 0.8 1.1 -1.0 -0.4 -1.4 -0.0 1.0
Blood Eosinophil Count 0.1 0.5 2.1 0.1 0.0 -1.1 0.3 -0.8 -0.3 0.0 -0.1 -0.6 -0.5 -1.4 0.5 0.6 -0.5 0.1 -0.2 0.9 -0.9 -0.2 -1.5 -1.3
Blood Platelet Count 0.2 2.6 7.6 -1.8 -2.5 -1.7 1.4 -2.7 -2.3 0.0 1.9 0.2 0.9 0.3 1.8 -0.1 -2.5 -0.0 -2.8 -0.2 -0.2 1.9 0.8 -1.0
Blood Red Count 0.0 0.3 1.5 0.5 0.1 -0.3 -0.4 -0.4 -0.6 0.0 -0.3 -1.0 1.2 -0.5 0.1 -0.5 -0.4 0.7 -0.7 0.6 -1.2 -0.3 0.1 -0.4
Blood White Count 0.1 1.0 5.5 0.9 0.0 -1.2 0.7 -0.3 -0.2 0.0 1.4 1.6 -1.1 -1.4 0.7 0.6 -0.6 0.4 -0.2 -0.4 -1.3 -0.8 -2.3 -0.9
Heel T-Score 0.2 1.5 5.8 -1.6 -1.1 -0.8 -2.4 -0.6 -0.5 0.0 0.4 -1.6 -0.2 0.5 -2.4 -2.2 -1.0 -0.6 -1.0 0.9 0.6 1.7 -0.3 -0.4
BMI 0.1 0.8 2.6 -1.2 1.2 0.7 0.2 1.1 1.6 0.0 1.4 0.5 0.9 -0.6 0.7 0.8 1.1 1.3 0.6 -0.4 -0.2 -0.9 -0.2 0.9
Height 0.5 10.2 57.5 0.4 -0.4 -2.0 -6.9 1.0 -0.1 0.0 -0.6 1.8 -4.0 3.6 -7.6 -5.7 -1.1 -3.6 -0.5 0.3 2.5 2.8 -3.1 0.6
Waist Hip Ratio (WHR) 0.5 2.4 6.3 1.0 1.1 0.5 2.5 1.4 0.7 0.0 2.2 2.1 1.0 -2.0 2.5 2.2 1.2 1.4 1.3 -1.7 -1.1 -1.8 0.9 1.2
Systolic Blood Pressure 0.6 3.1 9.1 -1.4 -2.4 -1.4 -1.2 -2.7 -3.0 0.0 0.3 -0.2 -0.2 1.5 -1.1 -2.0 -2.7 -0.9 -2.8 2.2 -0.5 1.6 -0.4 -2.3
Smoking Status 0.4 0.9 4.1 0.6 0.9 0.9 -1.1 0.7 1.8 0.0 1.1 0.6 -0.1 0.7 -0.9 0.0 1.1 0.3 0.8 0.8 2.0 -0.2 -0.2 1.3
Allergy or Eczema 0.4 1.2 8.5 -0.1 -0.1 -0.1 0.9 -0.4 -0.8 0.0 -0.6 -1.0 0.2 -0.6 0.9 0.8 -0.1 0.7 0.6 -0.8 -2.9 -1.6 -0.1 -2.6
Cardiovascular Disease 0.2 0.5 6.7 -1.0 0.2 -0.1 -0.7 -0.2 0.2 0.0 0.3 -0.3 -0.1 -0.8 -0.7 -0.2 0.0 0.4 -0.3 2.6 1.2 0.1 -0.5 -0.1
Hypothyroidism (self reported) 0.5 1.2 3.9 0.7 1.0 1.5 1.4 1.0 0.7 0.0 1.0 2.0 1.0 -1.0 1.2 0.8 1.1 1.2 1.4 -0.7 -0.3 -1.6 1.3 0.9
Respiratory disease 0.5 1.1 6.1 -0.6 0.0 1.1 1.2 -0.3 -0.5 0.0 2.5 1.3 1.5 -0.7 1.3 0.5 -0.1 1.7 -0.5 0.2 -1.5 -0.7 0.9 -0.7
Type 2 Diabetes (T2D) (2018) 0.6 1.2 4.6 0.3 -1.5 -0.9 0.5 -2.1 -1.1 0.0 0.2 -1.4 0.7 -1.3 0.9 0.0 -1.3 -0.9 -1.4 1.7 0.5 1.4 1.0 -0.7
Lung FEV1/FVC ratio 0.4 1.8 4.8 2.0 -0.8 -1.8 -1.7 -1.2 -0.3 0.0 -0.3 -0.1 -2.2 1.5 -2.0 -1.1 -0.9 -1.6 -1.1 1.1 0.5 0.4 -2.2 -1.7
Lung FVC 0.9 4.7 12.2 2.8 2.0 1.1 3.4 0.9 0.5 0.0 -1.4 -1.6 1.2 -0.9 3.0 3.3 1.8 2.0 2.3 -3.4 -2.9 -3.5 0.3 -1.1
Neuroticism 0.2 0.5 2.0 1.2 0.6 0.9 0.7 0.4 0.9 0.0 -0.1 0.5 -0.3 -1.4 0.5 0.8 0.4 0.3 0.2 -0.4 0.3 -0.7 -1.0 0.5
Chronotype (morning person) 0.9 2.1 6.6 0.5 -2.0 -1.2 0.2 -2.0 -2.4 0.0 -1.2 -2.6 0.7 -0.6 0.6 -1.0 -1.8 -1.3 -2.1 0.2 -0.6 1.0 2.1 -1.5
Hair Pigment 0.0 0.3 2.7 -0.0 0.3 0.6 0.1 0.0 -0.2 0.0 -0.4 -1.6 -0.1 -0.5 0.2 -0.1 -0.0 0.5 -0.2 -0.3 0.9 0.1 -0.7 -0.5
Tanning 0.1 1.1 2.7 1.1 1.3 0.2 1.0 1.6 1.6 0.0 0.8 1.4 0.2 -0.4 1.0 1.3 1.3 0.9 1.6 -0.5 -0.1 -1.4 -0.4 0.7
Hand grip strength (left) 0.4 1.1 3.9 -0.5 -1.1 -0.6 -1.2 -1.3 -1.3 0.0 -0.4 -2.0 -0.1 0.8 -1.1 -1.7 -1.4 -0.9 -1.1 0.2 -0.6 0.6 -0.6 -1.6
Number of treatments/medications taken 0.7 1.3 3.9 1.6 1.3 0.3 1.5 0.6 1.2 0.0 1.4 1.8 -0.3 -1.5 1.0 2.0 1.1 0.9 1.2 0.5 -0.1 -1.6 -0.9 -0.1
Average weekly spirits intake 0.3 0.3 1.0 0.6 1.0 0.8 0.5 0.3 0.8 0.0 -0.1 -0.8 0.1 -0.5 0.5 0.6 1.0 0.6 0.3 0.2 -0.5 -1.0 -0.4 0.2
Sensitivity / hurt feelings 0.2 0.4 1.5 0.3 0.6 0.7 0.6 0.4 0.4 0.0 -0.8 -1.2 0.1 -0.2 0.6 0.7 0.1 1.1 0.1 0.2 -0.9 -0.8 -0.6 0.4
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.2 0.5 0.6 1.5 0.5 0.9 1.1 0.0 0.3 0.5 0.6 1.3 0.3 0.8 0.8 0.7 0.8 -0.9 0.3 -0.9 0.5 1.5
Hearing difficulty/problems: Yes 0.5 0.8 3.8 1.7 1.1 -0.0 0.0 1.3 0.3 0.0 -0.0 1.3 -0.9 -0.8 -0.2 0.4 1.1 -0.2 0.6 -0.7 -1.3 -1.9 -0.7 -0.7
Relative age of first facial hair 0.1 0.3 1.4 1.2 -0.4 0.3 0.6 -0.5 -0.5 0.0 -0.5 0.3 -0.6 -0.2 0.5 0.2 -0.7 -0.4 -0.3 0.4 0.3 0.3 -1.2 0.0
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 4.0 1.3 1.3 2.0 1.2 1.5 1.4 0.0 -0.6 0.6 0.8 -0.2 1.0 2.0 1.5 1.4 0.5 -1.4 0.6 -1.5 0.5 1.9
Ever used hormone-replacement therapy (HRT) 0.8 1.0 5.5 0.2 0.4 -0.7 -0.5 0.5 0.5 0.0 0.9 1.8 -2.4 -0.9 -1.2 -0.5 -0.1 -0.6 0.3 0.5 0.0 -0.3 -2.3 -0.7
Ever had hysterectomy (womb removed) 0.6 0.7 3.2 0.3 -0.9 0.0 -1.0 -0.5 -1.0 0.0 0.3 -0.5 0.3 0.3 -1.0 -1.4 -0.4 -1.6 -0.9 0.7 -0.2 0.3 1.8 -0.8
Systolic blood pressure, automated reading 0.5 1.6 4.5 -0.3 -1.2 -1.3 -1.1 -1.7 -1.8 0.0 -0.9 -1.0 -1.0 0.9 -0.9 -1.1 -1.7 -0.8 -1.6 2.1 -0.8 0.7 -1.0 -2.1
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 4.2 0.7 0.6 2.0 0.1 0.7 0.9 0.0 0.8 -0.1 1.7 0.3 0.3 0.7 0.9 0.2 0.4 -0.7 0.9 -0.7 1.4 0.9
Angina 1.5 2.0 4.9 1.9 2.1 1.4 1.1 1.6 2.2 0.0 0.3 -0.5 0.4 0.6 0.9 2.1 2.0 1.7 1.8 -0.2 0.3 -2.1 -1.5 0.2
Medication for hormone replacement therapy 2.3 2.5 9.2 0.8 -0.7 -1.9 -2.8 0.4 -0.0 0.0 -0.7 0.5 -2.3 -1.3 -3.0 -2.3 -0.7 -2.1 -0.0 2.1 1.1 1.3 -2.1 -1.1
Vitamin and mineral supplements 1.0 1.4 3.9 0.8 1.8 1.2 0.7 1.7 2.0 0.0 0.3 0.6 0.5 -1.1 1.1 1.5 1.8 1.3 1.5 -0.3 0.2 -1.6 -0.7 0.7
Supplements: Zinc 0.6 0.6 2.0 0.2 0.7 0.6 1.4 0.3 0.6 0.0 0.6 0.5 0.4 -0.7 1.2 1.4 0.7 0.9 1.1 -0.6 -0.8 -1.1 0.4 0.6
Medication: Co-codamol 0.5 0.5 4.8 1.3 -0.2 0.2 -0.0 -0.3 0.2 0.0 -0.2 -0.4 0.1 2.2 -0.4 -0.1 0.3 -0.2 0.4 1.6 -0.4 -0.4 0.7 -0.6
Medication: Metformin 0.5 0.7 3.5 0.4 -0.7 -1.0 0.9 -1.9 -1.0 0.0 0.7 -0.9 0.1 -1.3 0.8 0.5 -0.6 -0.2 -0.9 0.3 -0.1 -0.1 0.4 -1.2
Diabetes (father) 0.8 1.0 4.5 -0.5 0.2 1.1 1.6 -0.5 0.3 0.0 0.8 0.3 1.8 0.4 2.1 1.6 0.3 1.3 -0.2 -1.0 -0.5 -0.0 1.2 1.0
Diabetes (mother) 1.2 1.5 6.2 1.4 0.6 0.3 2.5 0.3 0.9 0.0 1.0 0.5 0.1 -2.2 2.4 1.8 0.8 0.4 0.8 -0.1 -1.6 -1.5 0.5 0.2
Severe depression (siblings) 0.3 0.3 1.3 0.6 0.5 0.4 0.8 0.4 0.5 0.0 0.3 -0.3 0.7 0.2 0.6 0.6 0.4 0.6 0.6 -1.2 0.4 -0.4 0.1 0.7
Pack years adult smoking proportion 0.6 0.9 3.8 -0.1 -0.9 -0.8 0.9 -1.6 -0.8 0.0 -0.9 -2.0 -0.4 -1.5 0.8 0.7 -1.0 -0.5 -1.3 0.2 0.5 0.5 -0.3 -1.0
Impedance of leg (right) 0.2 1.1 3.6 -1.1 0.0 1.9 0.2 -0.7 0.3 0.0 0.9 1.0 1.9 1.3 0.8 0.0 0.2 0.8 -0.4 -0.6 1.7 1.2 1.6 1.3
Leg fat-free mass (left) 0.3 1.7 8.9 0.6 -0.2 -1.5 -2.7 0.5 -0.2 0.0 -0.3 -0.3 -1.8 0.1 -3.0 -2.2 -0.5 -1.6 -0.7 0.4 0.4 0.7 -1.9 -0.6
Trunk fat percentage 0.2 0.8 3.4 -1.5 -0.4 -0.4 -1.6 -1.2 -0.4 0.0 -0.0 -1.1 0.2 -0.1 -0.9 -1.4 -0.8 0.3 -1.8 0.5 0.7 1.0 -0.4 -0.6
Hand grip strength (right) 0.2 0.4 1.6 0.3 -0.5 -0.6 -0.2 -0.8 -0.9 0.0 0.3 -0.8 -0.4 0.8 -0.6 -0.7 -0.9 -0.9 -0.5 0.4 -0.8 0.2 -0.9 -1.3
Townsend deprivation index at recruitment 1.3 1.9 4.5 0.5 1.4 2.1 1.8 0.6 1.4 0.0 0.4 -1.4 1.5 0.7 1.7 2.1 1.7 1.2 1.4 -0.1 0.5 -1.6 1.7 1.6
Current tobacco smoking 0.8 1.2 4.7 0.1 1.0 0.9 1.2 0.3 1.0 0.0 2.2 1.3 1.7 1.2 1.0 1.0 0.7 2.1 0.5 -0.4 0.8 -1.0 0.7 1.2
Average weekly fortified wine intake 0.6 0.7 3.2 -0.8 -0.0 0.3 -0.0 0.1 0.1 0.0 1.6 0.3 1.3 1.0 0.1 -0.1 0.5 0.6 -0.0 0.1 1.6 0.8 1.8 0.9
Maternal smoking around birth 1.2 1.8 7.3 -1.7 0.9 1.9 -0.6 1.1 1.6 0.0 1.3 -0.1 2.3 -0.4 -0.2 -0.3 1.2 1.2 1.0 0.4 2.7 0.8 1.8 2.1
Fed-up feelings 0.4 0.6 2.2 1.5 0.8 0.4 0.5 1.1 1.2 0.0 -0.4 0.3 -0.5 -0.8 -0.1 0.7 0.6 0.4 0.2 -0.5 1.2 -0.5 -1.2 1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 6.4 -1.4 -0.0 1.3 0.1 0.5 0.4 0.0 0.6 0.4 1.6 0.7 0.3 -0.1 0.3 1.0 -0.5 -1.3 1.5 0.6 1.4 2.5
Relative age voice broke 0.5 0.8 3.7 1.2 -0.3 0.2 1.5 -0.6 -0.8 0.0 -1.9 -1.4 -0.2 -1.3 1.6 1.0 -0.6 0.0 0.2 -0.1 -0.2 -0.2 -1.0 -0.3
Taking other prescription medications 0.9 1.3 3.8 1.1 1.2 1.0 1.2 1.2 1.6 0.0 1.1 2.0 -0.0 -0.5 0.9 1.8 1.4 1.1 1.1 -0.7 -0.0 -1.9 -0.4 0.8
Age when periods started (menarche) 0.1 0.3 2.2 0.4 -0.1 0.0 0.6 -0.4 -0.0 0.0 -0.9 -1.5 -0.5 -0.4 0.7 0.7 -0.4 -0.1 0.0 0.8 0.2 0.1 -0.9 0.6
Bilateral oophorectomy (both ovaries removed) 3.2 3.7 10.9 -1.4 -1.9 -2.2 -2.9 -1.7 -1.1 0.0 -0.1 0.1 -1.3 0.9 -2.9 -3.0 -1.6 -2.6 -1.9 3.3 1.6 2.8 -0.1 -1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 2.0 -1.4 0.1 0.1 -1.4 0.6 0.4 0.0 1.0 -0.3 0.0 0.1 -1.4 -1.2 0.3 0.0 0.2 -0.2 0.9 0.2 -0.0 0.3
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 5.0 1.4 -0.2 -0.5 0.9 0.3 -0.2 0.0 -2.2 -0.6 -1.4 0.1 0.0 1.1 -0.1 -0.3 -0.0 -0.6 -1.1 -0.7 -0.8 0.3
Qualifications: CSEs or equivalent 1.4 1.9 12.5 0.4 -1.5 -0.8 -0.5 -2.0 -0.9 0.0 -0.6 -0.3 -0.9 -1.2 -0.4 -0.5 -1.2 -2.1 -1.9 3.5 1.4 1.7 -0.7 -1.1
Serious illness, injury or assault to yourself 1.6 2.0 5.5 1.9 2.0 1.9 0.2 2.2 1.9 0.0 -1.5 -0.6 0.4 0.1 0.1 0.9 1.8 1.5 1.8 -1.2 -0.5 -2.4 -0.6 1.4
High blood pressure 0.7 1.9 6.5 0.1 -0.8 -2.5 -0.4 -1.2 -1.5 0.0 -0.4 -0.2 -1.9 -2.5 -0.6 -0.4 -1.3 -1.3 -1.3 2.5 -0.4 0.2 -1.5 -2.1
Hayfever, allergic rhinitis or eczema 0.6 1.2 6.4 0.3 -0.1 0.7 1.6 -0.5 -0.7 0.0 -0.5 -1.2 1.0 -0.7 1.8 1.2 0.1 0.7 0.6 -0.5 -2.5 -1.4 0.7 -1.9
Multivitamins +/- minerals 1.2 1.5 4.2 -0.6 -1.8 -1.0 -1.1 -1.8 -2.0 0.0 -0.1 -0.6 -0.3 1.5 -1.3 -1.8 -1.8 -1.4 -1.6 0.0 -0.3 1.6 0.8 -0.7
Stomach or abdominal pain in last month 0.2 0.2 0.7 0.8 -0.8 -0.2 -0.3 -0.7 -0.6 0.0 -0.2 0.2 -0.2 -0.0 -0.1 -0.5 -0.6 -0.6 -0.7 0.6 0.4 0.6 -0.3 -0.3
Supplements: Glucosamine 0.8 1.0 3.4 -0.5 -0.9 -1.1 -0.4 -1.4 -1.5 0.0 -1.5 -1.9 -0.9 -0.4 -0.2 -0.8 -1.4 -0.9 -1.2 -0.3 -0.7 0.7 -0.1 -1.4
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 3.6 0.8 0.2 0.1 0.1 0.2 -0.3 0.0 -1.9 -1.2 0.2 -0.9 -0.1 0.2 0.2 0.0 0.2 0.3 0.0 -0.3 0.9 0.4
Medication: Atenolol 0.8 1.0 3.2 0.8 0.2 -0.4 -1.3 0.7 0.6 0.0 1.4 1.8 -1.2 -0.5 -1.3 -0.8 0.3 -1.2 -0.4 1.3 1.8 0.5 -0.6 0.7
Medication: Levothyroxine sodium 1.7 2.9 5.9 -0.7 1.4 2.0 1.8 1.7 1.6 0.0 2.1 2.4 1.8 -0.4 2.1 2.0 1.8 2.2 2.1 -1.0 -0.9 -1.8 1.9 1.5
Sitting height 0.7 5.0 18.5 -0.4 -2.2 -1.6 -4.1 -1.7 -1.9 0.0 -0.1 -0.5 -1.2 2.0 -4.1 -4.3 -2.3 -2.9 -2.4 1.3 1.5 3.0 -0.6 -1.2
Chronic bronchitis/emphysema (father) 0.6 0.7 2.9 -1.2 -0.7 -0.1 0.0 -1.7 -0.7 0.0 -0.5 -1.7 -0.1 0.2 -0.1 -0.2 -0.8 -0.7 -0.9 1.0 1.0 1.5 0.8 -0.3
High blood pressure (mother) 1.3 1.8 6.8 -1.3 -1.7 -1.0 -1.0 -1.5 -1.6 0.0 0.8 1.2 -0.3 0.7 -0.9 -1.6 -1.6 -1.5 -2.6 2.0 0.1 1.6 0.0 -1.3
Body mass index (BMI) 0.1 0.3 1.1 -0.5 0.6 -0.5 -0.6 0.1 0.5 0.0 0.3 -0.8 0.0 -1.1 -0.3 -0.0 0.3 0.9 -0.6 0.2 -0.2 -0.4 -0.9 -0.4
Impedance of leg (left) 0.2 1.0 3.3 -1.5 -0.3 1.5 0.3 -0.9 -0.0 0.0 1.0 0.6 1.8 1.7 0.8 -0.1 -0.2 0.9 -0.5 -0.1 1.4 1.3 1.4 1.1
Leg predicted mass (left) 0.3 1.8 9.6 0.6 -0.3 -1.5 -2.8 0.4 -0.2 0.0 -0.3 -0.2 -1.8 0.2 -3.1 -2.3 -0.6 -1.6 -0.7 0.4 0.5 0.8 -2.0 -0.7
Trunk fat mass 0.2 0.8 4.2 -1.2 -0.2 -0.7 -2.0 -0.7 -0.2 0.0 0.3 -0.7 -0.2 0.1 -1.6 -1.7 -0.6 -0.0 -1.6 0.3 0.7 1.0 -0.7 -0.5
Waist circumference 0.1 0.2 1.4 0.1 0.5 -0.6 -0.1 0.4 0.3 0.0 1.2 0.5 -0.6 -1.0 -0.1 0.2 0.4 0.1 -0.5 -0.3 -0.6 -0.5 -0.5 -0.3
Number of incorrect matches in round 0.2 0.4 2.2 0.8 0.1 0.2 -1.5 0.3 -0.2 0.0 -0.6 -0.2 0.3 -1.3 -1.2 -0.9 -0.1 -0.1 -0.5 -0.5 0.8 0.1 0.1 0.4
Past tobacco smoking 0.4 0.8 3.4 -1.2 -0.4 -0.3 1.4 -0.5 -0.9 0.0 0.4 0.2 1.8 -0.3 1.5 0.0 -0.7 1.1 -0.5 -1.4 -1.0 0.1 1.2 -0.2
Alcohol usually taken with meals 0.7 1.2 5.0 0.7 -1.0 -2.2 -1.1 -0.8 -1.4 0.0 -0.3 0.8 -1.8 0.5 -1.2 -1.3 -1.3 -1.2 -0.9 -0.1 -0.2 0.7 -1.4 -1.3
Nervous feelings 0.2 0.4 1.8 -0.5 0.1 1.3 1.0 -0.0 0.6 0.0 0.9 0.6 1.1 -0.3 0.9 1.0 0.3 0.7 0.2 -0.3 0.2 -0.1 0.3 0.7
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 2.6 -0.3 -0.7 0.4 -0.3 -0.4 -0.0 0.0 0.8 1.0 0.8 1.6 0.0 -0.6 -0.4 -0.1 -0.7 0.2 1.0 0.7 0.5 0.7
Hearing difficulty/problems with background noise 0.6 0.9 4.1 1.9 0.8 0.2 0.3 1.1 0.3 0.0 -1.4 -0.7 -1.0 -0.5 0.1 0.6 1.0 -0.8 0.4 -0.2 -1.5 -2.0 0.3 -0.7
Hair/balding pattern: Pattern 2 0.8 1.0 3.1 0.6 -1.0 0.1 1.6 -1.2 -0.6 0.0 -0.8 -1.4 -0.1 -0.6 1.6 0.9 -1.2 -0.1 -1.2 -1.2 -1.8 -0.4 0.1 -0.6
Had menopause 0.3 0.4 2.4 0.3 -0.1 -0.8 -0.4 -0.1 -0.3 0.0 -0.4 0.7 -1.6 -0.9 -0.7 -0.3 -0.0 -1.0 0.2 0.6 -0.1 -0.0 0.1 -0.8
Had other major operations 0.6 0.8 3.1 -1.4 -1.1 0.7 -0.1 -0.9 -0.9 0.0 1.8 0.6 1.1 0.3 -0.1 -0.5 -0.7 0.0 -1.2 0.4 0.6 1.0 1.5 0.4
Forced vital capacity (FVC) 0.1 0.5 4.3 -0.1 -0.1 0.4 -0.7 0.2 -0.4 0.0 -0.7 -0.7 0.9 2.1 -0.6 -0.6 0.0 0.0 0.1 -1.4 0.1 0.1 0.8 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 3.4 -1.7 -0.1 0.5 -1.6 0.1 0.3 0.0 1.5 -0.3 1.0 0.3 -1.2 -1.4 0.1 0.7 -0.1 0.3 1.9 0.7 0.6 0.6
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 7.2 -0.2 -0.3 1.3 0.3 0.6 0.5 0.0 -2.7 -2.7 0.5 1.2 0.3 0.7 0.3 -0.2 0.3 -1.1 -1.3 -0.6 1.0 0.3
Qualifications: None of the above 0.1 0.2 1.6 0.5 0.6 0.3 -0.1 -0.1 0.2 0.0 0.3 -1.3 0.4 -0.5 -0.0 0.2 0.4 0.5 0.1 0.8 0.3 -0.8 0.1 -0.5
Financial difficulties in last 2 years 0.6 0.8 2.8 1.7 -1.0 -0.4 -0.3 -1.3 -0.2 0.0 -0.5 -0.5 -0.7 1.5 -0.7 -0.6 -1.1 -1.2 -0.9 1.4 0.7 1.0 -0.4 0.5
Mouth/teeth dental problems 0.3 0.4 1.5 0.2 -0.8 -0.7 -0.6 -0.3 -0.8 0.0 -0.6 -0.4 -0.5 0.0 -0.8 -1.1 -0.5 -1.2 -0.8 0.3 0.3 1.0 0.0 -0.1
Heart attack 0.4 0.5 2.3 1.3 -0.3 -0.3 0.2 -0.5 -0.5 0.0 1.1 1.0 -1.1 0.2 0.2 0.4 -0.2 -1.5 -0.2 0.7 -0.7 -0.3 -0.4 -0.9
Allergy 0.8 1.8 5.1 -0.6 -1.2 -0.9 -2.2 -0.9 -0.3 0.0 -0.7 -0.6 -0.7 1.2 -2.2 -2.1 -1.0 -1.4 -1.3 1.2 2.1 2.3 -0.4 0.6
Pain all over the body in last month 0.8 0.9 3.5 0.5 -0.9 -0.1 -1.2 -1.2 -0.8 0.0 -1.8 -1.9 -0.4 -0.1 -0.7 -0.8 -1.0 -0.3 -1.1 1.4 0.5 0.8 -0.8 -0.9
Diabetes (self-reported) 0.3 0.4 1.7 1.2 -0.0 -0.9 1.1 -0.6 -0.1 0.0 0.1 -0.4 -0.2 -1.3 0.9 0.9 0.1 -0.2 0.3 0.1 0.1 -0.6 -0.2 -0.5
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.3 1.1 0.4 0.5 -0.2 0.6 0.7 0.0 -0.3 0.4 -0.7 1.2 -0.6 -0.0 0.8 -0.8 0.9 -0.0 0.1 -0.3 -0.2 -0.7
Medication: Ramipril 0.3 0.4 1.4 -0.6 -0.4 -1.2 -0.5 0.1 -0.5 0.0 0.5 0.7 -1.1 -0.5 -0.8 -0.4 -0.5 -1.1 -0.0 0.4 -0.3 0.7 -0.9 -0.8
Medication: Simvastatin 0.2 0.3 1.3 -0.2 0.1 0.2 -0.0 0.3 0.3 0.0 1.1 -0.1 0.7 -1.1 0.1 0.1 0.4 0.1 -0.5 0.1 0.8 -0.1 0.8 0.7
Fluid intelligence score 0.6 1.3 7.6 1.5 -1.1 -1.6 1.0 -1.0 -1.4 0.0 -1.1 -0.6 -0.9 -0.1 1.0 0.5 -1.1 -0.4 -0.1 -1.0 -2.8 -0.6 -0.6 -2.0
Illnesses of siblings 0.7 1.0 5.2 -0.8 0.6 1.4 -0.7 -0.1 0.3 0.0 -0.4 -1.6 2.3 1.2 -0.2 -0.5 0.8 0.8 0.9 -0.0 0.8 0.5 2.0 0.5
Neuroticism score 0.2 0.5 2.3 0.7 0.7 0.9 0.4 0.5 1.1 0.0 -0.8 -0.2 -0.2 -0.7 0.2 0.7 0.4 0.9 0.1 -0.3 0.7 -0.6 -1.5 1.0
Weight 0.3 1.3 7.5 -0.1 0.1 -1.2 -2.7 0.3 0.1 0.0 0.2 -0.3 -1.1 0.1 -2.6 -2.0 -0.3 -0.6 -1.0 0.2 0.7 0.7 -1.6 -0.3
Impedance of arm (right) 0.4 2.0 6.7 -2.3 -1.2 1.0 -1.5 -1.6 -1.1 0.0 -0.3 -0.2 1.5 1.5 -0.8 -2.2 -1.1 -0.3 -1.5 1.0 1.5 2.6 2.0 0.5
Arm fat percentage (right) 0.1 0.4 2.2 -1.5 0.3 0.0 -0.8 -0.5 0.2 0.0 0.3 -1.0 0.6 -0.6 -0.2 -0.5 0.0 1.2 -1.2 0.4 0.0 0.1 -0.4 -0.5
Trunk fat-free mass 0.4 2.2 12.3 1.2 -0.0 -1.4 -3.0 1.1 0.0 0.0 -0.1 0.4 -2.1 1.1 -3.5 -2.3 -0.2 -1.8 -0.1 -0.3 0.6 0.5 -2.1 -0.3
Hip circumference 0.2 0.8 4.1 -0.2 -0.1 -1.0 -2.0 0.1 -0.1 0.0 0.4 0.0 -1.1 -0.2 -1.9 -1.5 -0.2 -0.9 -1.1 0.1 0.1 0.5 -1.0 -0.6
Time employed in main current job 0.3 0.4 1.6 0.5 0.4 -0.3 -0.1 -0.0 0.5 0.0 -0.8 -0.2 -1.3 -0.3 -0.6 0.1 0.6 -0.5 0.4 0.9 1.2 -0.3 -0.9 -0.4
Alcohol intake versus 10 years previously 2.7 4.1 13.3 2.3 3.4 1.3 0.3 3.1 3.6 0.0 1.3 2.8 -0.6 -0.0 -0.2 1.6 3.2 1.5 2.6 -0.1 1.1 -2.2 -1.7 1.7
Father’s age at death 1.6 2.1 6.9 -0.5 -2.4 -1.8 0.7 -2.2 -2.6 0.0 -0.8 -1.1 0.7 -0.0 1.1 -0.8 -2.0 -1.1 -2.1 0.4 -0.9 1.9 2.0 -0.9
Worrier / anxious feelings 0.2 0.3 1.5 0.6 -0.3 0.2 -0.4 -0.2 -0.0 0.0 -0.3 -0.8 -0.8 -0.0 -1.2 -0.6 -0.5 -0.5 -0.5 0.7 -0.1 -0.1 -1.1 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 2.4 1.4 -1.3 -1.1 -0.1 -1.1 -1.3 0.0 -1.6 -1.2 -1.1 0.1 -0.1 -0.3 -1.1 -1.2 -1.1 1.0 -0.7 0.2 -0.3 -1.0
Falls in the last year 0.5 0.7 5.2 2.3 -0.1 -1.1 0.4 -0.2 -0.0 0.0 -0.8 0.1 -1.1 -0.5 0.2 0.7 -0.2 -0.5 -0.4 -0.1 -0.2 -0.6 -2.0 -0.9
Hair/balding pattern: Pattern 3 0.6 0.9 5.6 0.4 -0.4 -0.9 0.4 -0.4 -1.4 0.0 -0.4 -0.2 -1.4 -0.6 0.1 -0.3 -0.6 -0.9 -0.4 -0.1 -2.1 -1.0 -0.8 -2.4
Number of live births 0.9 1.3 5.0 0.6 2.1 0.9 0.2 1.5 2.2 0.0 -0.1 0.8 -0.2 -0.3 0.2 1.2 1.7 1.4 1.6 -0.6 0.1 -1.6 -1.1 0.9
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 6.7 0.8 -0.6 0.2 -1.6 -0.4 -0.7 0.0 -1.0 -1.3 0.6 2.6 -1.4 -1.3 -0.3 -0.6 -0.4 -0.4 0.8 0.6 0.6 -0.4
Pulse rate 0.8 1.3 4.9 -1.6 -0.7 -0.5 -2.0 -0.6 -1.0 0.0 0.3 -0.5 0.5 2.0 -2.0 -2.2 -0.9 -0.2 -0.9 -1.0 0.7 1.5 0.2 0.4
Happiness 0.4 0.5 2.2 0.8 -0.2 0.8 0.5 -0.1 -0.1 0.0 -1.5 -1.4 0.4 -1.2 0.4 0.1 0.0 -0.1 0.1 -0.6 -0.8 -0.4 1.2 0.2
Noisy workplace 0.2 0.2 2.3 0.0 -0.0 -0.2 0.1 -0.1 0.6 0.0 -0.2 -0.7 -0.3 0.0 -0.3 0.5 0.3 -0.2 0.3 1.5 0.6 0.2 0.1 -0.2
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.6 1.2 0.1 0.2 -0.0 -0.1 -0.5 0.0 0.0 -0.1 -0.0 1.1 -0.1 0.2 0.3 -0.4 0.3 -0.6 -0.7 -0.2 0.8 -0.6
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.6 0.2 -0.2 0.1 0.4 -0.4 0.0 0.0 0.6 -0.2 0.0 -0.0 0.4 0.4 0.0 -0.4 0.1 0.7 -0.1 -0.4 0.8 0.0
Mouth/teeth dental problems: Dentures 0.8 1.4 4.7 1.1 1.7 0.9 0.5 1.0 1.7 0.0 2.2 1.3 0.6 0.6 0.1 1.1 1.6 1.2 1.5 1.3 0.4 -1.6 0.4 0.6
Asthma 0.3 0.5 3.8 -0.3 -0.1 -0.1 1.2 -0.0 -1.0 0.0 0.2 0.2 0.4 -0.6 1.1 0.4 -0.2 0.9 -0.5 0.1 -2.0 -0.8 0.3 -0.6
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.2 3.0 0.6 -1.5 -1.6 0.0 -1.3 -1.2 0.0 -0.3 1.0 -1.5 -0.8 -0.3 -0.6 -1.7 -0.8 -1.1 0.7 -1.5 0.3 -1.7 -1.6
Medication: Cholesterol lowering 0.3 0.5 1.6 -0.4 -0.8 -1.1 0.2 -0.8 -0.8 0.0 0.0 -1.0 -0.7 -0.6 0.1 0.1 -0.6 -1.3 -0.6 -0.8 -0.6 -0.1 -0.2 -1.2
Depression (self-reported) 1.6 1.9 9.3 0.9 -0.1 0.6 2.5 -0.4 -0.6 0.0 -0.3 -0.8 -0.0 -1.4 2.5 1.6 -0.2 0.3 0.0 -3.0 -2.8 -1.8 0.9 -0.4
Medication: Lansoprazole 0.6 0.7 2.8 1.4 0.7 0.4 1.2 0.5 0.5 0.0 0.0 -1.1 0.4 0.6 1.0 1.7 0.9 1.0 0.8 0.2 -0.2 -1.3 -0.1 0.0
Prospective memory result 0.7 0.9 3.3 -1.1 0.2 0.1 -1.6 0.6 0.3 0.0 -1.8 -1.7 -0.3 -0.3 -1.7 -1.5 -0.1 -0.2 -0.6 -0.2 0.6 0.9 -0.6 0.8
Lung cancer (father) 0.3 0.3 3.3 0.7 -0.0 0.2 0.3 -0.0 -0.2 0.0 0.5 0.1 0.4 0.4 0.5 0.4 0.2 -0.7 -0.4 1.0 0.2 0.2 1.8 0.0
Illnesses of mother 0.2 0.2 1.7 0.2 -0.1 -0.3 0.1 0.1 -0.1 0.0 -1.3 -1.1 -0.2 -0.3 0.0 0.2 -0.3 0.2 0.4 -0.6 0.2 0.5 -0.3 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.1 6.2 1.0 -0.8 -0.1 -1.4 -0.9 -1.1 0.0 -1.4 -1.8 0.6 2.5 -1.2 -1.3 -0.6 -0.9 -0.6 -0.4 0.5 0.6 0.2 -0.9
Pulse wave Arterial Stiffness index 2.1 2.4 5.6 1.1 -2.3 -2.1 -1.1 -1.9 -2.0 0.0 -0.7 0.6 -2.1 -0.6 -1.3 -1.1 -2.2 -2.1 -2.4 1.7 -0.5 1.4 -1.1 -1.3
Impedance of arm (left) 0.3 1.4 4.9 -1.8 -1.0 0.8 -1.3 -1.3 -0.9 0.0 -0.7 -0.4 1.0 1.1 -0.8 -1.8 -1.0 -0.2 -1.1 0.6 1.4 2.2 1.5 0.6
Arm fat mass (right) 0.1 0.4 2.1 -0.6 0.3 -0.3 -1.5 -0.1 0.3 0.0 0.3 -0.8 -0.1 -0.3 -1.1 -0.9 0.0 0.5 -1.0 0.4 0.3 0.2 -1.0 -0.4
Trunk predicted mass 0.4 2.1 11.6 1.3 0.1 -1.3 -2.9 1.2 0.1 0.0 -0.1 0.4 -2.1 1.1 -3.4 -2.2 -0.1 -1.7 -0.0 -0.4 0.6 0.4 -2.1 -0.2
Standing height 0.6 6.3 31.8 0.6 -1.1 -1.6 -5.3 0.5 -1.0 0.0 -0.2 1.1 -2.5 2.9 -5.6 -4.8 -1.4 -3.3 -1.1 0.1 2.0 2.6 -1.7 0.2
Length of working week for main job 0.9 1.0 2.4 0.1 -1.4 -0.6 -0.6 -1.2 -1.5 0.0 -0.3 -1.6 0.3 0.8 -0.3 -0.9 -1.1 -1.3 -1.5 0.8 -0.1 1.1 1.1 -1.2
Exposure to tobacco smoke at home 0.9 1.0 5.2 -0.7 1.0 2.3 -0.8 0.8 1.4 0.0 0.5 0.4 1.5 1.4 -0.8 -0.6 1.1 0.8 0.5 0.3 1.7 -0.1 0.5 1.1
Breastfed as a baby 0.2 0.2 1.3 -1.1 -0.2 0.5 0.0 -0.6 -0.1 0.0 -0.3 -0.7 0.6 0.4 0.3 -0.1 -0.1 0.1 -0.2 -0.4 0.4 0.1 1.2 0.2
Tense / ‘highly strung’ 0.4 0.7 3.2 -0.6 -0.4 1.3 1.1 -0.5 -0.2 0.0 1.0 -0.4 1.8 -0.3 1.2 0.7 0.0 0.4 -0.1 -0.1 -0.5 0.1 1.8 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 1.7 1.3 0.6 0.9 -0.3 0.3 0.5 0.0 0.0 0.2 -0.6 -0.3 -0.9 -0.1 0.6 -0.6 0.4 -1.1 0.1 -1.0 0.3 0.2
Hair/balding pattern: Pattern 4 0.8 2.0 9.9 0.2 -0.7 -1.4 -3.2 -0.6 -0.4 0.0 -0.7 0.2 -0.9 1.0 -3.1 -2.2 -0.8 -1.0 -0.8 1.9 1.9 1.5 -1.0 -0.4
Birth weight of first child 0.2 0.4 2.8 0.8 0.1 -0.0 0.7 -0.8 -0.5 0.0 0.5 0.3 -0.6 -0.7 0.5 0.5 -0.1 0.2 0.4 0.1 -1.7 -0.6 -0.4 -0.9
Peak expiratory flow (PEF) 0.8 1.9 5.9 0.7 -1.6 -0.5 -2.4 -1.4 -1.2 0.0 -0.4 -0.4 -0.2 1.5 -2.3 -2.0 -1.4 -1.6 -1.5 1.7 1.6 1.8 -0.3 -0.7
Pulse wave reflection index 0.5 0.6 1.7 0.6 -0.8 -0.7 1.3 -0.5 -0.3 0.0 -0.1 0.4 -1.2 -0.7 1.0 1.2 -0.5 -1.1 -1.1 0.9 -1.0 -0.2 -0.0 -0.4
Ever highly irritable/argumentative for 2 days 1.6 1.9 5.6 0.5 2.0 1.8 -0.8 2.0 2.4 0.0 -0.1 0.9 1.6 0.3 -0.5 0.4 2.2 1.4 2.1 0.6 1.4 -0.8 1.1 1.9
Loud music exposure frequency 0.7 0.8 3.3 0.8 0.3 0.5 0.6 0.0 1.5 0.0 0.4 1.5 -0.2 -1.0 0.5 0.9 0.5 0.1 0.3 1.3 1.8 0.5 -0.6 1.5
Qualifications: O levels/GCSEs or equivalent 0.5 0.7 5.2 -1.2 -1.0 -0.5 0.1 -0.6 -0.9 0.0 0.8 0.8 1.1 1.0 0.3 -0.1 -0.4 0.2 -0.3 0.2 -0.2 1.4 2.3 0.5
Mouth/teeth dental problems: Bleeding gums 0.3 0.5 2.2 -1.5 -0.9 -0.3 0.2 -0.8 -0.8 0.0 -0.6 -0.0 -0.0 -0.9 0.5 0.1 -0.8 -0.3 -0.8 -0.4 0.3 1.2 -0.2 -0.5
Blood clot in the leg (DVT) 1.1 1.5 5.3 -0.4 1.7 0.8 0.3 2.1 1.2 0.0 0.8 0.6 1.5 -0.6 0.3 0.9 1.4 2.3 1.1 -1.3 0.8 -1.2 0.7 2.1
Medication: Paracetamol 0.2 0.3 2.1 1.4 0.2 -0.3 -0.3 -0.1 0.6 0.0 -0.6 -0.4 -0.5 -0.7 -0.6 -0.1 0.0 -0.0 -0.4 0.8 0.5 0.4 -1.1 0.4
Headache pain in last month 0.6 1.0 3.6 1.8 -0.4 -1.3 -0.3 -0.5 -0.2 0.0 -1.5 -0.5 -1.9 -1.6 -0.5 -0.6 -0.7 -1.2 0.0 0.5 -0.1 -0.2 -1.9 -0.8
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 1.3 0.7 0.7 1.0 0.5 0.4 0.9 0.0 -0.4 0.1 0.5 0.9 0.3 0.5 0.6 1.1 0.8 0.4 0.6 0.0 0.1 1.1
Glaucoma (self-reported) 0.7 0.8 3.6 0.5 1.5 0.9 0.1 1.2 0.7 0.0 -0.8 -0.4 0.5 -0.7 -0.1 0.6 1.4 1.1 1.3 -1.1 -0.8 -1.9 0.1 0.3
Gout (self-reported) 1.4 1.9 5.7 1.5 2.4 0.8 0.7 2.2 2.1 0.0 1.4 0.9 -0.5 -0.1 -0.1 1.8 2.3 1.5 1.4 -0.5 0.1 -2.1 -1.0 0.7
Hypothyroidism/myxoedema (self-reported) 0.4 0.9 2.5 0.8 0.4 1.2 1.4 0.4 0.3 0.0 0.6 1.3 1.2 -0.4 1.5 1.0 0.6 1.0 0.9 -0.2 -0.6 -1.3 1.6 0.5
Medication: Amlodipine 3.0 4.2 9.1 1.4 -2.7 -2.4 -2.0 -2.2 -2.7 0.0 -1.7 -1.5 -1.6 0.4 -2.0 -2.1 -2.3 -3.0 -2.9 3.0 0.6 2.1 -0.4 -2.1
Medication: Ventolin 100micrograms inhaler 0.8 1.0 4.5 -0.2 -1.4 0.3 -0.1 -1.7 -1.6 0.0 0.3 -0.3 0.9 0.8 0.5 -0.5 -1.3 0.3 -0.9 2.1 -0.6 0.9 0.9 -1.3
Birth weight 0.3 0.7 2.8 -0.2 1.0 0.3 0.5 1.0 1.3 0.0 -0.7 -1.0 0.2 0.9 0.1 0.5 1.1 0.7 0.9 -1.6 0.6 -0.4 -0.0 1.7
Chronic bronchitis/emphysema (mother) 0.3 0.4 3.5 -0.6 -0.1 0.8 -0.0 -0.1 0.5 0.0 -0.4 -0.4 0.5 -0.1 0.2 0.1 0.1 0.0 -0.3 0.5 1.9 1.1 0.4 0.8
High blood pressure (siblings) 1.2 1.7 5.2 -0.0 -2.0 -2.3 -0.0 -1.4 -1.9 0.0 0.1 0.2 -1.5 -0.4 -0.3 -0.8 -2.0 -1.8 -1.9 1.6 -0.5 1.3 -0.4 -1.4
Forced vital capacity (FVC), Best measure 0.2 0.7 3.2 0.4 -0.6 0.2 -0.5 -0.6 -1.1 0.0 -0.9 -1.7 1.1 1.8 -0.2 -0.6 -0.4 -0.4 -0.4 -1.3 -0.2 0.1 0.7 -0.5
Body fat percentage 0.2 0.6 2.9 -1.6 -0.2 -0.4 -1.2 -1.1 -0.2 0.0 0.4 -1.0 0.3 -0.3 -0.5 -0.9 -0.5 0.6 -1.7 0.4 0.4 0.8 -0.3 -0.7
Leg fat percentage (right) 0.1 0.3 1.3 -1.0 0.7 -0.2 -0.2 -0.3 0.6 0.0 0.8 -0.3 0.3 -1.0 0.3 0.2 0.4 1.1 -0.7 -0.3 0.1 -0.3 -0.7 -0.5
Arm fat-free mass (right) 0.3 1.5 7.5 1.1 0.2 -1.5 -2.2 1.1 0.2 0.0 -0.1 0.1 -2.1 0.4 -2.7 -1.4 -0.1 -1.2 0.0 -0.2 0.4 0.1 -2.3 -0.2
Exposure to tobacco smoke outside home 1.2 1.6 5.9 -1.3 1.0 2.1 0.9 0.6 0.8 0.0 2.4 1.0 2.0 1.6 1.0 1.0 1.0 1.9 0.0 0.6 -0.0 -0.6 1.2 1.2
Comparative body size at age 10 0.4 1.2 5.2 -1.3 1.5 1.0 0.6 1.3 1.4 0.0 -0.3 -0.8 0.4 0.0 0.8 1.2 1.4 1.5 1.5 -2.3 -0.2 -1.4 0.3 0.6
Number of full brothers 0.5 0.7 1.9 -0.5 1.0 0.8 1.0 0.8 0.7 0.0 0.2 0.2 0.5 -0.5 1.1 1.1 0.6 1.4 0.6 -1.1 -0.9 -1.4 -0.6 -0.1
Worry too long after embarrassment 0.8 1.3 5.6 -0.1 0.7 0.9 2.4 0.5 0.5 0.0 -0.3 -0.7 1.1 -1.5 2.2 1.7 0.8 1.6 0.3 -0.9 -1.0 -1.5 0.9 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.4 3.6 1.9 1.1 1.9 1.7 0.8 1.5 0.0 0.8 0.4 0.1 -0.5 1.4 1.9 1.4 0.4 0.7 -1.5 -0.3 -1.6 0.1 0.5
Wheeze or whistling in the chest in last year 0.9 1.5 5.3 1.0 0.7 0.8 2.1 -0.1 0.4 0.0 1.7 0.3 1.0 -2.3 2.3 1.8 0.5 1.5 0.3 -0.1 -1.5 -1.7 0.4 0.3
Number of children fathered 1.1 1.2 4.1 1.4 1.5 1.0 -0.0 1.8 2.0 0.0 -0.0 0.6 -0.1 -0.6 0.2 1.3 1.4 1.0 1.6 -1.0 -0.0 -1.3 -1.0 1.0
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 2.4 0.9 -0.2 0.2 -0.1 -1.1 0.1 0.0 -1.5 -1.1 0.2 -1.1 -0.0 -0.2 -0.2 0.1 -0.3 0.5 1.4 0.8 -0.3 0.3
Age at first live birth 2.7 4.8 12.6 -0.3 -3.5 -2.1 -1.9 -3.1 -3.3 0.0 -1.0 -0.5 -1.4 1.7 -1.6 -2.8 -3.3 -3.0 -2.4 1.8 -0.7 2.5 0.1 -2.8
Pulse wave peak to peak time 2.0 2.4 5.7 -1.0 2.3 2.1 0.7 2.0 2.1 0.0 0.8 -0.4 2.0 0.7 0.9 0.8 2.2 2.1 2.4 -1.7 0.9 -1.3 0.9 1.5
Health satisfaction 0.3 0.3 1.7 0.5 0.5 -0.1 0.0 0.4 0.5 0.0 -0.7 -0.3 -1.3 -1.3 -0.7 0.1 0.3 -0.5 0.4 0.2 0.4 -0.1 -0.9 0.3
Shortness of breath walking on level ground 0.6 0.7 3.8 -1.9 0.1 0.6 0.4 -0.6 0.1 0.0 0.2 -0.9 1.8 -0.4 0.4 0.3 0.2 1.6 -0.7 -0.2 0.7 0.6 1.3 0.4
Qualifications: College or University degree 0.2 0.7 3.1 -0.2 -1.1 -0.6 0.4 -0.5 -1.5 0.0 -0.6 -0.4 -0.4 1.5 0.5 -0.3 -0.9 -0.6 -0.1 -1.8 -1.3 0.5 0.4 -0.9
Eye problems/disorders: None of the above 0.5 0.6 2.9 0.1 -0.7 -0.6 -0.3 -0.8 -0.4 0.0 0.5 0.4 -0.6 -0.2 -0.4 -0.9 -0.9 -0.7 -0.7 1.6 1.2 1.7 -0.3 0.5
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.0 -0.2 1.2 1.0 1.0 0.5 0.3 0.0 0.7 -0.5 -0.4 -0.8 0.6 1.1 0.6 1.6 0.5 -2.0 -1.4 -1.6 -1.3 -0.1
Emphysema/chronic bronchitis 1.1 1.2 7.8 0.6 0.5 1.6 0.1 0.4 0.6 0.0 2.8 1.0 1.7 1.4 0.7 0.5 0.6 1.2 -0.4 -0.3 1.1 -0.1 1.4 1.4
Medication for pain relief, constipation, heartburn 0.6 1.1 6.1 -2.0 -0.8 0.6 -0.9 -0.7 -0.9 0.0 0.0 -1.6 1.6 0.5 -0.1 -1.3 -0.5 -0.2 -0.3 0.1 0.4 1.2 2.5 0.1
Neck or shoulder pain in last month 1.1 1.6 5.4 2.2 0.5 -0.8 2.3 0.6 -0.3 0.0 -1.4 -0.7 -1.2 -1.1 1.9 2.0 0.5 0.0 0.7 -0.7 -1.8 -1.9 -0.4 -0.9
Medication: Blood pressure 0.6 1.1 3.8 -0.8 -1.0 -1.9 -1.3 -0.8 -0.9 0.0 -0.4 -0.0 -1.7 -1.1 -1.1 -0.9 -1.0 -1.6 -1.0 0.9 -0.2 0.7 -1.1 -1.4
Angina (self-reported) 1.4 1.8 4.7 2.1 2.1 1.2 1.0 1.5 2.2 0.0 0.5 -0.4 0.4 0.8 0.8 1.9 2.0 1.5 1.7 0.1 0.4 -2.0 -1.3 0.2
Migraine (self-reported) 0.2 0.2 1.3 0.6 0.1 0.0 0.2 0.4 0.3 0.0 -0.2 -0.2 0.0 -0.3 -0.2 0.0 0.3 0.0 1.1 0.2 0.4 -0.2 1.1 0.5
Medication: Ibuprofen 1.0 1.2 4.8 0.5 -1.4 -1.3 0.5 -1.7 -1.4 0.0 0.0 0.8 -0.9 -0.6 0.2 -0.4 -1.7 -0.6 -0.8 1.0 -1.8 0.2 -1.5 -2.2
Medication: Allopurinol 0.9 1.2 4.0 1.5 1.6 0.6 0.7 1.5 1.1 0.0 1.8 1.0 -0.4 0.1 0.2 1.6 1.3 1.0 1.0 -0.4 -0.8 -2.0 -0.5 0.1
Medication: Omeprazole 0.2 0.2 1.3 -0.8 0.2 0.3 0.0 -0.2 0.2 0.0 -0.2 -0.0 0.3 -0.2 0.3 0.0 0.0 0.4 0.3 -0.1 -1.2 -0.6 -0.6 -0.7
Medication: Seretide 50 evohaler 0.5 0.6 2.8 1.0 0.3 0.5 1.6 -0.4 0.1 0.0 -0.0 -0.3 0.6 -1.7 1.6 0.8 -0.2 0.8 -0.4 -0.1 0.1 -0.5 0.2 0.8
Mean time to correctly identify matches 0.9 1.6 4.3 0.7 1.6 1.2 1.2 2.1 1.8 0.0 -0.3 1.2 0.5 0.1 1.2 1.5 2.0 0.9 2.0 -1.6 0.2 -1.3 0.5 1.3
Heart disease (mother) 0.3 0.4 3.3 -1.3 0.3 0.2 0.0 0.1 0.3 0.0 1.8 0.8 0.3 0.4 0.3 0.0 0.3 0.1 -0.2 -1.1 -0.4 -0.4 1.0 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 3.6 -1.5 -0.7 0.4 -0.8 -1.0 -0.2 0.0 -1.0 -1.7 1.5 1.7 -0.4 -0.7 -0.6 0.5 -0.8 0.4 1.9 1.4 1.2 0.4
Whole body fat mass 0.2 0.6 3.1 -1.1 -0.1 -0.6 -1.8 -0.5 -0.1 0.0 0.5 -0.7 -0.3 -0.1 -1.4 -1.3 -0.3 0.1 -1.4 0.4 0.6 0.8 -0.8 -0.5
Leg fat mass (right) 0.1 0.3 1.5 -0.6 0.6 -0.4 -0.9 -0.0 0.6 0.0 0.7 -0.3 -0.3 -0.9 -0.7 -0.4 0.3 0.5 -0.8 0.0 0.3 0.1 -1.2 -0.4
Arm predicted mass (right) 0.3 1.6 8.8 1.1 -0.1 -1.5 -2.4 0.7 -0.0 0.0 0.0 -0.1 -2.0 0.8 -3.0 -1.7 -0.3 -1.4 -0.4 0.1 0.7 0.5 -2.2 -0.3
Pulse rate, automated reading 0.1 0.4 1.9 -0.7 0.2 -0.3 -0.5 -0.1 -0.3 0.0 0.8 0.8 0.8 1.4 -0.5 -0.8 -0.1 0.9 0.3 -0.9 -0.4 -0.1 -0.3 0.3
Alcohol intake frequency. 1.5 3.5 10.6 1.9 2.0 1.2 2.6 2.4 1.6 0.0 1.0 1.5 1.1 -1.2 2.3 3.2 2.3 1.2 1.6 -1.8 -1.4 -3.0 1.6 1.5
Comparative height size at age 10 0.5 3.0 17.6 -0.4 0.3 -1.2 -4.2 1.3 -0.1 0.0 0.5 1.3 -1.4 1.5 -4.2 -3.5 -0.2 -1.3 -0.4 -1.6 -0.4 0.2 -1.1 -0.1
Number of full sisters 0.5 0.6 2.0 -0.4 -0.2 1.1 0.8 -0.9 0.1 0.0 -0.4 -1.4 0.9 -0.8 1.3 0.8 -0.1 1.0 -0.5 0.6 0.6 0.4 1.0 0.5
Suffer from ‘nerves’ 1.5 2.3 5.7 0.5 2.0 2.2 1.5 1.5 2.4 0.0 0.3 -0.0 0.7 -0.6 1.4 2.4 1.8 2.1 1.8 -1.5 0.4 -2.0 -0.8 1.5
Overall health rating 0.2 0.5 2.3 1.5 0.7 0.6 0.7 0.5 0.7 0.0 0.2 0.4 -0.2 -1.0 0.4 1.4 0.7 0.4 0.4 0.4 0.5 -0.9 -0.1 0.8
Chest pain or discomfort 0.6 0.9 3.2 -0.5 -1.3 -0.9 -0.4 -1.8 -1.4 0.0 -0.4 -1.0 -0.5 0.1 -0.8 -0.8 -1.6 -0.5 -1.2 1.1 -0.3 0.8 -0.3 -1.5
Had major operations 0.2 0.2 1.6 0.5 -0.1 -0.2 -0.7 -0.3 -0.2 0.0 -0.8 -0.0 -0.6 0.5 -0.4 0.1 -0.5 0.3 -0.4 0.5 0.3 -0.4 -1.3 -0.4
Age at last live birth 0.9 1.2 3.9 0.7 -1.6 -0.2 0.3 -1.7 -1.8 0.0 -0.8 -0.7 -0.0 2.0 0.4 -0.4 -1.3 -1.5 -1.4 0.1 -1.2 0.3 1.6 -1.3
Family relationship satisfaction 0.3 0.3 1.2 0.1 -0.0 0.6 0.9 0.4 0.5 0.0 -0.6 -0.4 -0.1 -1.0 0.7 0.8 0.1 0.4 0.1 -0.9 0.6 -0.0 0.1 1.1
Leg pain on walking 2.7 3.4 10.3 -0.6 2.8 1.6 0.5 2.9 3.2 0.0 1.1 2.5 0.2 0.2 0.3 1.8 2.6 2.1 2.6 -1.8 1.1 -1.5 -1.0 2.3
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 2.8 0.2 1.2 1.2 0.5 1.3 1.7 0.0 1.0 1.3 0.5 0.9 0.4 1.3 1.3 0.3 1.3 0.8 -0.3 -1.0 0.2 0.8
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.9 -1.7 -0.7 0.1 -1.0 -0.6 -0.7 0.0 -1.1 -1.2 -0.7 -0.1 -0.9 -1.2 -0.7 -0.6 -0.1 0.3 -0.3 0.7 -0.2 -0.8
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.8 -1.3 0.2 0.2 -0.3 0.6 -0.0 0.0 0.2 -0.5 0.5 -0.5 -0.1 -0.3 0.5 0.1 0.5 0.2 0.4 0.5 0.2 -0.3
Medication: Aspirin 0.2 0.3 1.4 0.1 0.0 -0.9 0.7 -0.3 -0.4 0.0 0.4 0.2 -0.9 -0.1 0.5 0.8 -0.1 -0.3 -0.6 0.1 -0.4 -0.6 -1.1 -1.2
Supplements: Vitamin C 0.5 0.6 2.0 -0.1 -1.3 -0.5 0.7 -0.8 -1.2 0.0 -0.3 0.0 -0.2 -1.4 0.5 0.2 -0.8 -1.1 -0.3 0.4 -0.6 0.6 1.2 -0.5
Knee pain experienced in last month 0.4 0.7 3.1 -0.1 0.5 -0.2 1.3 0.4 0.2 0.0 0.1 1.7 -0.2 -0.4 1.2 1.8 0.5 0.9 0.6 -0.7 -0.9 -1.2 -0.0 -0.1
Hypertension (Self-reported) 0.7 1.9 7.6 -0.5 -1.1 -2.3 -1.1 -1.3 -1.7 0.0 -0.5 -0.4 -1.3 -1.7 -1.2 -1.1 -1.6 -1.1 -1.7 2.8 0.3 0.9 -1.3 -1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 1.1 0.4 0.3 0.1 0.3 0.0 0.0 0.0 -0.4 0.1 -0.6 -1.1 -0.1 0.3 0.2 0.2 0.6 -0.1 -0.6 -0.7 -0.6 -0.2
Illnesses of father: Heart disease 1.0 1.3 11.7 -0.1 0.8 -1.4 -1.1 0.1 0.5 0.0 -0.6 1.4 -2.1 -0.7 -1.4 -0.5 0.0 0.0 0.2 -0.3 -0.7 -1.1 -3.4 -0.6
Illnesses of siblings: Diabetes 2.0 2.5 5.7 1.9 1.7 0.9 2.0 1.6 2.0 0.0 1.3 1.6 -1.0 -1.7 1.5 2.4 1.7 0.8 1.6 -1.7 1.0 -2.0 -1.4 1.3
Smoking status: Previous 1.0 1.4 6.9 1.6 0.3 -0.1 -1.8 0.5 0.8 0.0 -1.7 -0.6 -2.6 0.2 -1.8 -0.4 0.7 -2.0 0.5 1.4 0.6 -0.1 -1.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.7 5.3 -2.1 -1.3 -0.6 -2.0 -1.0 -1.0 0.0 1.2 -0.0 0.3 1.9 -1.6 -2.3 -1.4 -0.7 -1.2 0.6 1.1 2.1 -0.6 -0.2
Whole body fat-free mass 0.3 1.9 11.0 0.9 -0.1 -1.5 -2.9 0.9 -0.1 0.0 -0.1 0.2 -2.0 0.9 -3.3 -2.2 -0.3 -1.7 -0.3 -0.0 0.4 0.5 -2.0 -0.5
Leg fat-free mass (right) 0.3 1.8 9.7 0.5 -0.3 -1.7 -2.8 0.6 -0.2 0.0 -0.1 -0.3 -1.9 0.5 -3.1 -2.3 -0.5 -1.5 -0.6 0.7 0.3 0.7 -2.0 -0.7
Arm fat percentage (left) 0.1 0.4 1.9 -1.4 0.2 -0.0 -0.7 -0.6 0.1 0.0 0.2 -1.2 0.5 -0.7 -0.1 -0.4 -0.1 1.1 -1.2 0.4 -0.0 0.2 -0.3 -0.5
Average weekly red wine intake 1.3 1.9 5.8 0.1 -1.3 -2.4 -1.7 -1.0 -1.2 0.0 -1.2 0.3 -2.0 0.1 -1.6 -1.9 -1.4 -2.2 -1.0 0.8 0.4 2.0 -1.2 -0.8
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.9 -1.3 0.2 1.1 -0.4 0.0 0.1 0.0 -0.9 -0.5 1.4 0.6 0.3 -0.3 0.2 0.8 -0.1 -0.3 -0.1 0.0 1.3 0.5
Mood swings 1.3 2.4 8.0 0.3 2.3 2.1 0.7 2.1 2.8 0.0 -0.5 0.1 0.7 0.5 0.7 1.6 2.2 1.9 1.7 -0.8 2.1 -1.0 -0.9 2.4
Loneliness, isolation 0.6 0.8 2.9 1.7 -1.0 -0.6 -0.9 -0.5 -0.9 0.0 -1.2 -0.5 -1.1 -0.7 -0.9 -0.9 -1.1 -1.1 -1.3 0.6 0.2 0.6 -0.9 -0.2
Long-standing illness, disability or infirmity 1.2 1.9 5.4 1.8 1.4 1.5 1.6 1.0 1.2 0.0 1.0 2.3 0.3 -1.1 1.6 2.1 1.3 1.0 0.7 -1.8 0.1 -1.8 0.6 1.3
Ever had bowel cancer screening 0.7 0.8 4.1 1.3 -0.1 -0.4 0.5 -0.2 -0.6 0.0 -1.7 -1.0 -0.6 -2.0 0.7 0.6 -0.2 -0.7 -0.5 -1.1 -1.0 -0.8 -0.5 -0.7
Diabetes diagnosed by doctor 0.2 0.3 1.7 1.0 -0.2 -0.4 0.8 -1.0 -0.2 0.0 0.1 -0.6 0.0 -1.3 0.8 0.6 -0.1 -0.3 -0.1 0.6 0.8 -0.0 0.2 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 2.6 1.2 -0.4 -0.8 -1.0 -0.1 -0.8 0.0 -1.6 -0.7 -1.6 0.5 -1.4 -1.1 -0.6 -1.4 -0.8 -0.5 -1.5 -0.7 -1.3 -1.1
Friendships satisfaction 0.4 0.5 2.0 0.8 0.9 0.7 0.3 1.3 1.0 0.0 0.2 0.8 -0.2 -0.7 0.0 0.8 0.9 0.3 0.7 -0.3 -0.0 -0.5 0.6 1.4
Qualifications: nursing, teaching 1.4 2.1 8.4 -1.6 -1.2 -0.5 -2.4 -0.6 -1.5 0.0 -0.4 -0.2 -0.5 2.9 -2.7 -2.3 -1.1 -1.3 -1.1 0.4 0.9 2.2 0.0 -0.9
Commuting to job workplace: Walk 0.5 0.5 4.2 1.7 0.4 -0.1 0.6 1.0 0.0 0.0 -0.6 -0.3 -0.2 -0.2 0.0 0.3 0.3 0.0 0.7 -2.1 0.1 -0.6 -0.4 0.6
Eye problems/disorders: Cataract 0.2 0.2 1.1 -0.9 -0.1 -0.1 0.1 0.1 -0.4 0.0 0.4 1.0 0.2 0.0 0.3 0.2 0.2 -0.3 -0.1 -1.0 -0.9 -0.4 0.5 -0.5
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 3.7 1.2 -0.2 -0.3 -0.4 -0.8 -0.0 0.0 -0.9 -0.4 -0.7 0.0 -0.4 -0.3 -0.5 -0.3 0.2 0.8 0.5 0.2 -1.9 -0.7
Medication for cholesterol 0.5 0.8 9.4 -0.5 -0.6 0.8 0.2 -0.3 -0.4 0.0 -1.1 -0.4 0.3 1.2 0.6 -0.2 -0.4 -0.3 -0.2 -3.1 -0.1 0.6 0.6 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.3 2.7 9.0 2.2 1.8 0.9 2.4 1.5 2.0 0.0 0.2 0.7 -1.1 -2.1 1.6 3.0 1.8 1.3 1.6 -1.2 -0.1 -2.3 -1.3 1.2
Back pain experienced in last month 0.4 0.6 2.8 0.1 0.7 0.9 0.8 0.6 0.9 0.0 1.3 1.3 -0.0 1.7 0.6 0.8 0.7 0.4 0.1 0.2 -0.8 -0.7 0.2 0.2
Mineral and other dietary supplements 0.4 0.6 1.8 0.8 0.8 1.2 0.6 0.9 1.0 0.0 1.3 0.1 1.0 -0.1 0.4 0.8 1.1 0.8 0.8 -0.6 -0.1 -0.7 0.4 0.5
Breast cancer (self-reported) 1.6 1.9 5.2 -0.4 1.6 2.0 0.2 1.8 2.0 0.0 1.7 1.1 2.0 0.2 0.1 0.7 1.8 2.3 1.1 -0.0 1.2 -0.8 1.3 2.1
Asthma (self-reported) 0.3 0.5 3.8 -0.2 -0.0 0.1 1.3 -0.1 -0.9 0.0 0.3 0.3 0.5 -0.8 1.2 0.5 -0.2 1.0 -0.4 0.5 -1.9 -0.9 0.4 -0.5
Osteoporosis (self-reported) 0.5 0.7 3.2 -0.1 -0.9 -0.6 -1.0 -0.5 -0.5 0.0 -0.3 0.3 -1.0 0.5 -1.0 -0.8 -0.5 -1.8 -0.3 0.4 1.2 1.7 -0.5 -0.2
Osteoarthritis (self-reported) 0.3 0.4 4.0 0.7 0.2 0.4 0.3 -0.7 -0.0 0.0 -0.4 -0.7 0.2 2.0 0.3 0.5 0.2 0.8 0.2 0.1 0.4 -0.1 -0.3 -0.5
Medication: Aspirin 0.3 0.4 1.5 -0.0 0.1 -0.7 0.6 -0.0 -0.4 0.0 0.7 0.6 -0.9 0.6 0.3 0.8 -0.0 -0.3 -0.5 0.0 -0.5 -0.8 -1.1 -1.2
Medication: Gliclazide 0.6 0.7 4.6 2.1 -0.5 -1.0 -0.5 -1.0 -0.9 0.0 0.7 0.9 -0.3 0.3 -0.8 -0.5 -0.5 -1.0 -0.3 0.8 0.7 0.1 -0.4 -1.5
Illnesses of father: None of the above (group 1) 0.3 0.4 1.7 0.7 0.2 1.1 0.3 0.9 0.4 0.0 -0.1 -0.7 0.8 -0.2 0.1 0.4 0.5 0.1 1.0 -0.5 0.7 -0.0 1.3 0.9
Smoking status: Current 0.7 1.0 4.9 -0.1 0.8 0.7 1.0 0.2 0.8 0.0 2.2 1.1 1.6 1.4 0.7 0.8 0.6 1.9 0.4 -0.3 0.6 -0.9 0.8 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.1 3.8 0.2 -0.2 0.3 1.7 -0.6 -0.8 0.0 -1.3 -2.0 1.2 0.1 1.9 1.1 -0.0 0.5 0.2 -1.4 -1.4 -1.1 1.3 -1.0
Whole body water mass 0.3 1.9 10.8 1.0 -0.1 -1.5 -2.9 0.9 -0.1 0.0 -0.1 0.2 -2.0 0.9 -3.3 -2.2 -0.3 -1.7 -0.4 -0.0 0.4 0.5 -2.1 -0.4
Leg predicted mass (right) 0.3 1.8 9.8 0.5 -0.2 -1.6 -2.8 0.6 -0.2 0.0 -0.2 -0.4 -1.9 0.5 -3.1 -2.3 -0.5 -1.5 -0.5 0.7 0.3 0.7 -2.0 -0.6
Arm fat mass (left) 0.1 0.3 1.7 -0.7 0.3 -0.3 -1.3 -0.0 0.3 0.0 0.3 -0.7 -0.1 -0.4 -0.9 -0.8 0.0 0.5 -1.0 0.4 0.3 0.2 -1.0 -0.3
Number of self-reported non-cancer illnesses 0.4 0.7 2.3 1.0 0.8 0.4 1.0 0.4 0.2 0.0 1.2 1.4 -0.4 -1.0 0.6 1.4 0.7 0.4 0.6 0.5 -0.6 -1.5 0.0 -0.6
Average weekly champagne plus white wine intake 0.8 1.1 3.3 -0.4 -1.2 -0.7 -1.2 -0.9 -1.1 0.0 -1.7 -0.7 0.1 -0.6 -0.9 -1.8 -1.4 -0.7 -1.5 -1.1 0.7 1.5 -0.3 0.1
Miserableness 0.7 1.3 5.7 0.8 1.0 1.6 -0.3 0.7 1.7 0.0 -1.7 -2.2 0.4 -1.0 0.1 0.1 0.8 0.5 0.4 -0.2 2.4 0.1 -0.7 1.7
Guilty feelings 0.6 1.0 5.6 2.4 -0.0 -1.4 -0.7 0.1 0.2 0.0 -0.7 -0.0 -1.8 -0.3 -0.9 -0.2 -0.2 -1.2 0.1 1.0 0.0 -0.7 -2.0 -0.5
Wears glasses or contact lenses 0.3 0.3 1.4 0.8 0.0 -0.8 -0.4 0.0 -0.1 0.0 -0.7 -0.6 -1.2 -0.3 -0.8 -0.2 -0.0 -0.5 -0.2 -0.0 0.4 0.1 -1.2 -0.1
Ever taken oral contraceptive pill 0.6 0.6 2.3 -0.1 1.3 0.7 -0.7 0.9 1.5 0.0 1.4 -0.3 -0.0 1.2 -0.7 -0.0 1.3 0.3 1.2 0.5 0.6 -0.6 -0.5 0.1
Hearing aid user 0.8 0.9 3.9 -1.2 -0.2 0.3 -1.5 -0.2 0.3 0.0 2.0 1.7 0.9 1.3 -1.3 -1.4 -0.0 0.3 0.0 0.5 1.0 0.9 0.5 0.3
Mother’s age at death 0.6 0.8 6.5 -0.0 0.8 -0.1 0.7 0.9 0.5 0.0 -0.0 0.1 -0.1 0.0 0.2 0.5 0.9 0.3 1.1 -1.0 -2.5 -1.7 0.4 -1.3
Financial situation satisfaction 0.6 0.8 2.9 -0.7 -1.1 0.1 0.1 -1.1 -0.9 0.0 -1.3 -1.2 0.2 1.7 -0.3 -0.6 -1.0 -0.4 -1.0 0.4 -0.0 0.7 1.4 0.7
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.7 0.6 -0.3 -0.5 -0.8 -0.5 0.1 0.0 1.1 1.2 -0.3 -1.3 -0.9 -1.3 -0.2 -0.7 -0.3 1.2 0.9 0.5 0.0 0.1
Commuting to job workplace: Public transport 0.6 0.7 2.7 0.5 0.8 0.3 1.2 0.4 0.7 0.0 0.0 0.7 0.7 -0.8 1.7 1.5 0.9 0.8 1.1 -0.9 0.7 -0.5 0.4 0.8
Eye problems/disorders: Glaucoma 0.4 0.5 2.3 0.4 0.8 0.4 0.1 0.3 0.1 0.0 -1.5 -1.3 0.2 -0.7 0.1 0.4 0.7 0.7 0.7 -0.1 -0.6 -1.4 -0.2 -0.4
Medication: Blood pressure 0.4 0.7 6.9 -0.2 -0.2 -0.8 -0.4 -0.7 -1.2 0.0 0.6 0.3 0.1 -0.7 -0.5 -0.6 -0.7 0.2 -1.0 2.6 -0.1 0.2 0.1 -1.2
Pain type(s) experienced in last month: Hip pain 2.6 3.2 8.4 -0.2 2.7 1.4 1.0 2.0 2.5 0.0 2.2 2.3 0.6 -0.2 0.7 1.9 2.5 2.6 2.2 -2.9 -0.1 -2.2 -0.2 1.3
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.8 -0.2 -0.9 -0.6 -0.3 -1.0 -1.4 0.0 -1.3 -0.7 -0.1 0.8 -0.0 -0.5 -1.1 -0.3 -0.9 0.4 -0.4 0.3 0.6 -0.8
High cholesterol (Self-reported) 0.3 0.6 2.7 0.3 -0.7 -0.6 0.9 -1.1 -0.6 0.0 -0.1 -1.6 -0.4 -0.9 0.6 0.4 -0.6 -0.5 -0.7 1.0 -0.9 -0.3 -0.2 -1.2
Medication: Bendroflumethiazide 1.1 1.6 4.0 0.1 -1.9 -1.9 1.1 -1.7 -2.0 0.0 -0.2 0.2 -0.3 -1.8 1.2 0.5 -1.4 -1.4 -1.3 1.3 -1.6 0.5 1.0 -1.7
Medication: Paracetamol 0.3 0.5 1.9 1.0 -0.2 -0.1 -0.4 -0.5 0.5 0.0 -1.1 -0.7 0.2 -1.4 -0.2 -0.1 -0.3 -0.1 -0.6 1.3 1.1 1.0 -0.8 0.4
Medication: Lisinopril 0.5 0.7 5.5 -0.3 0.3 -0.9 0.1 0.3 0.6 0.0 1.2 2.3 -0.6 -1.7 0.0 -0.1 0.1 0.1 -0.3 -0.0 0.3 -0.0 -1.4 0.5
Medication: Atorvastatin 0.4 0.5 1.8 0.4 -0.7 -0.6 0.4 -1.1 -0.7 0.0 0.1 -0.7 -0.6 1.0 0.0 0.0 -0.9 -0.2 -1.1 0.0 -0.4 0.2 -1.0 -1.3
Illnesses of father: High blood pressure 3.2 4.0 9.0 1.0 -1.9 -2.3 -2.7 -2.2 -2.0 0.0 -0.6 0.0 -1.8 0.7 -2.9 -2.9 -2.1 -2.2 -2.0 2.8 -0.8 1.3 -2.1 -3.0
Alcohol drinker status: Never 2.0 2.4 6.7 0.7 1.2 1.8 2.1 1.4 0.7 0.0 0.6 0.2 1.6 -1.2 2.2 2.0 1.4 1.3 1.2 -1.4 -2.5 -2.6 2.1 0.9
Ever smoked 0.3 0.5 2.1 0.9 0.1 0.5 -0.8 0.2 0.7 0.0 0.5 0.2 -1.3 -0.5 -0.9 0.2 0.3 -0.6 0.0 1.2 1.4 0.4 -1.2 0.8
Basal metabolic rate 0.3 1.8 10.0 0.8 -0.1 -1.4 -2.9 0.8 -0.0 0.0 0.0 -0.0 -1.8 0.7 -3.2 -2.2 -0.3 -1.5 -0.5 0.1 0.5 0.6 -2.0 -0.4
Leg fat percentage (left) 0.1 0.4 1.7 -1.2 0.6 -0.3 -0.0 -0.4 0.6 0.0 0.8 -0.5 0.3 -0.8 0.5 0.3 0.3 1.3 -0.8 -0.1 -0.1 -0.3 -0.6 -0.5
Arm fat-free mass (left) 0.3 1.4 7.0 1.1 0.3 -1.3 -2.2 1.2 0.5 0.0 0.2 0.3 -1.8 0.6 -2.6 -1.4 0.1 -1.1 -0.1 -0.2 0.6 0.1 -2.2 -0.1
Number of operations (self-reported) 0.2 0.3 1.1 0.2 0.9 0.4 -0.0 0.2 0.6 0.0 0.6 -0.3 -0.2 0.9 -0.2 0.3 0.6 0.7 0.7 0.3 0.4 -1.0 -1.0 -0.2
Average weekly beer plus cider intake 0.2 0.3 1.0 -0.7 -0.1 0.7 0.8 -0.1 0.2 0.0 0.0 -0.7 0.6 -0.9 1.0 0.7 0.0 0.5 0.1 -0.2 -0.1 0.0 0.5 -0.1
Irritability 0.4 0.7 3.2 -0.5 0.9 0.3 -1.5 1.2 0.9 0.0 -0.6 0.3 -0.5 1.7 -1.8 -1.0 1.0 -0.2 0.3 -0.3 0.7 0.1 -0.2 0.4
Risk taking 0.4 0.5 1.6 -0.5 0.7 0.8 0.3 0.5 0.3 0.0 0.2 -0.6 1.2 1.2 0.9 0.5 0.7 1.2 0.3 -1.3 -0.0 -0.4 0.8 0.6
Ever had prostate specific antigen (PSA) test 0.7 0.9 3.7 0.3 0.4 -0.8 -1.1 1.0 0.3 0.0 -0.9 1.1 -1.6 -0.7 -1.2 -0.6 0.1 -0.2 0.3 -1.9 0.6 -0.2 -1.8 0.4
Fractured/broken bones in last 5 years 0.4 0.5 3.4 0.7 -0.4 -0.2 -0.5 -0.5 -0.0 0.0 1.0 0.2 0.1 -0.6 -0.8 -1.0 -0.2 -0.5 -0.7 1.4 1.8 1.0 -0.2 0.2
Age started oral contraceptive pill 1.6 2.0 7.6 -0.4 1.9 2.0 1.6 1.2 1.4 0.0 1.0 0.4 2.1 0.3 1.5 1.5 1.8 2.8 1.4 -0.8 0.0 -1.7 1.4 0.9
Diastolic blood pressure, automated reading 1.7 5.2 9.4 -0.6 -2.4 -2.8 -2.4 -2.9 -3.0 0.0 -2.0 -2.4 -1.7 0.2 -2.1 -2.6 -2.9 -2.1 -3.0 3.1 -0.6 2.3 -1.7 -2.8
Ever depressed for a whole week 0.5 0.6 4.1 0.9 0.3 0.6 0.4 0.3 1.1 0.0 -2.0 -1.8 -0.5 -0.6 -0.1 0.5 0.5 0.1 0.9 0.5 -0.5 -0.6 -0.7 0.4
Unable to work because of sickness or disability 1.3 1.7 3.7 -1.5 1.0 1.5 1.6 0.6 1.0 0.0 1.4 0.3 1.9 -0.2 1.7 1.3 1.1 1.8 -0.0 -1.7 1.0 -0.8 1.8 1.9
Commuting to job workplace: Cycle 0.3 0.4 2.3 1.2 -0.6 0.3 -0.4 -0.8 -0.3 0.0 0.3 -0.3 0.5 0.4 -0.5 -0.2 -0.3 -0.1 -0.6 0.5 1.5 0.9 0.1 -0.3
Myopia 0.5 0.7 1.9 0.3 0.7 0.7 1.2 0.7 0.7 0.0 -1.2 -0.2 0.2 -1.4 1.0 1.0 0.9 0.0 0.5 -1.1 -0.7 -1.1 0.0 0.9
Vascular/heart problems diagnosed by doctor 0.4 1.0 5.4 -0.6 -0.1 1.4 -0.1 0.4 0.6 0.0 -0.1 0.0 1.3 2.3 0.1 -0.3 0.4 0.6 0.4 -1.9 0.4 0.6 1.5 1.7
Cholesterol lowering medication 0.5 0.8 5.5 0.5 -0.3 0.8 1.1 -0.8 0.1 0.0 1.4 0.1 1.2 -0.6 1.2 0.5 -0.0 0.9 -0.8 2.3 0.5 0.1 1.1 0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.7 -0.4 0.7 0.5 0.9 0.2 0.6 0.0 -0.3 0.2 0.1 -0.1 0.8 0.9 0.4 1.2 0.7 -0.5 -1.3 -1.2 -1.0 -0.2
Pain experienced in last month 0.6 1.0 4.3 -1.3 -0.0 0.7 -2.1 -0.4 -0.2 0.0 0.7 -1.0 1.1 0.8 -1.5 -1.6 -0.1 -0.3 -0.2 0.3 1.9 1.4 0.5 0.5
Supplements: Calcium 0.6 0.7 1.9 0.4 1.0 1.2 1.4 0.2 0.8 0.0 -0.3 -0.4 0.7 0.1 1.3 1.2 1.2 0.8 1.1 0.8 0.9 -0.3 0.1 0.7
Basal cell carcinoma (self-reported) 0.5 0.6 2.3 0.4 0.8 0.0 -0.7 1.0 0.7 0.0 1.1 0.8 -0.5 -0.0 -1.2 0.2 0.7 0.4 1.5 -0.5 -0.2 -1.1 -0.7 0.2
Heart attack/myocardial infarction (self-reported) 0.4 0.5 3.0 1.2 -0.5 -0.4 0.1 -0.7 -0.6 0.0 1.0 0.8 -1.2 0.0 0.2 0.4 -0.3 -1.7 -0.3 1.0 -0.4 -0.0 -0.2 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 5.5 -0.6 1.6 0.9 0.4 1.9 1.1 0.0 0.8 0.1 1.7 -0.8 0.5 0.9 1.3 2.3 1.1 -1.4 0.6 -1.3 1.0 2.1
Heart disease (siblings) 0.8 1.0 4.5 0.8 0.3 -0.6 1.0 0.7 -0.2 0.0 -1.0 -0.5 -1.1 -1.3 0.2 0.8 -0.1 0.4 0.3 -2.1 -1.9 -1.6 -1.7 -0.5
Alcohol drinker status: Previous 0.6 0.7 2.8 0.9 -1.0 -0.0 -0.2 -0.9 -0.5 0.0 -1.1 -0.7 0.2 0.2 0.1 -0.3 -0.6 -0.8 -1.1 1.7 1.3 1.5 0.8 0.4
Pack years of smoking 0.3 0.5 2.6 0.2 -0.4 -0.7 0.8 -1.1 -0.2 0.0 -0.5 -1.1 -0.5 -1.6 0.7 0.8 -0.5 -0.2 -0.8 0.0 0.8 0.2 -0.6 -0.7
Impedance of whole body 0.3 1.3 4.6 -1.6 -0.9 1.0 -0.7 -1.5 -0.7 0.0 0.0 0.0 1.5 1.5 -0.1 -1.2 -0.9 0.1 -1.1 0.6 1.6 2.2 1.6 0.8
Leg fat mass (left) 0.1 0.3 1.5 -0.7 0.6 -0.5 -0.8 0.0 0.6 0.0 0.7 -0.4 -0.3 -0.7 -0.6 -0.3 0.3 0.7 -0.8 0.0 0.2 -0.1 -1.2 -0.4
Arm predicted mass (left) 0.2 1.2 6.8 1.1 0.3 -1.1 -2.2 1.2 0.4 0.0 0.2 0.2 -1.5 0.9 -2.6 -1.4 0.2 -1.0 -0.2 -0.2 0.6 0.1 -2.0 0.1