Hub : Genes

ADAM33

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2550	0.0770	6.0e-04	0.093	NA	0.097	NA	0.133	7.9e-06	NA	5.5e-06	NA	8.8e-08
2	GTEx	Artery Tibial	0.3188	0.0693	2.9e-06	0.102	NA	0.108	NA	0.112	2.3e-08	NA	9.0e-09	NA	4.8e-09
3	GTEx	Esophagus Mucosa	0.1420	0.0480	1.4e-03	0.041	NA	0.011	NA	0.023	9.6e-04	NA	5.4e-02	NA	1.1e-02
4	GTEx	Nerve Tibial	0.2462	0.0779	6.2e-03	0.016	NA	0.062	NA	0.038	2.4e-02	NA	3.3e-05	NA	1.0e-03
5	ROSMAP	Brain Pre-frontal Cortex	0.1952	0.0399	1.4e-09	0.019	0.097	0.130	0.109	0.116	1.5e-03	2.1e-12	2.1e-16	7.5e-14	1.1e-14
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0691	0.0253	4.7e-05	0.025	0.040	0.041	NA	0.038	6.4e-04	2.2e-05	1.9e-05	NA	4.0e-05
7	TCGA	Lung Adenocarcinoma	0.0536	0.0210	8.7e-05	0.024	0.037	0.023	NA	0.026	7.5e-04	2.9e-05	9.2e-04	NA	4.3e-04
8	TCGA	Lung Squamous Cell Carcinoma	0.0612	0.0242	1.5e-04	0.023	0.030	0.024	NA	0.019	1.1e-03	2.3e-04	8.7e-04	NA	2.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.8	1.3	3.2	-0.9	-1.1	0.1	-1.8	-0.7	-0.9	-1.8	-0.8
Bipolar Disorder or Schizophrenia	0.2	0.5	1.5	0.8	1.1	-0.1	0.2	0.1	0.6	-1.2	-0.4
Depressed Affect (Nagel 2018)	0.2	0.5	2.4	0.6	0.3	-0.4	0.7	0.7	-0.2	1.5	-0.1
Depression (Nagel 2018)	1.0	1.5	4.6	-0.0	-0.7	-2.0	-0.3	1.5	-0.8	-0.1	-2.1
Intelligence (Savage-Jansen 2018)	0.8	2.6	5.7	1.4	1.5	-0.8	2.4	2.1	1.3	1.7	1.0
Neuroticism (Nagel 2018)	0.2	0.5	1.4	-0.6	0.1	-0.0	0.2	1.2	0.1	1.0	-1.0
Schizophrenia (2018)	1.0	2.1	6.5	1.8	2.6	-0.2	1.7	0.6	1.8	-0.1	0.2
Schizophrenia vs Biploar Disorder	1.3	1.8	4.8	1.7	2.2	0.9	1.7	0.7	1.5	0.1	0.4
Worry (Nagel 2018)	0.9	1.9	5.4	-1.4	-0.9	-1.6	-1.3	1.5	-0.5	-0.5	-2.3
Alzheimer’s Disease (in mother)	1.2	1.4	8.1	-0.2	-0.5	-2.8	-0.3	-0.6	-0.3	-1.6	-0.3
Alzheimer’s Disease (in father)	0.8	0.9	2.9	-1.0	-0.8	-0.7	-0.5	-0.2	-0.8	-1.1	-1.7
Alzheimer’s Disease (including proxy)	0.6	0.8	4.0	-0.1	-0.2	-2.0	-0.1	-0.2	0.1	-1.5	-0.7
Crohns Disease (2017)	0.9	1.9	4.2	2.0	1.5	-1.4	0.9	1.4	1.8	0.3	0.9
Irritable Bowel Disease (IBD)	0.4	0.9	2.8	1.5	0.7	-1.7	0.0	0.6	0.9	-0.4	0.6
Ulcerative Colitis (UC)	0.2	0.3	1.2	0.1	-0.6	-1.1	-0.8	0.3	-0.2	-0.4	0.1
Major Depression (MDD)	0.2	0.3	1.6	0.0	0.0	0.5	0.4	0.5	0.0	1.3	0.0
Reaction Time	0.2	0.5	1.5	0.3	-0.1	-1.0	-0.9	-0.5	-0.2	-1.2	-0.1
Verbal and Numeric Reasoning (VNR)	2.6	6.3	13.8	2.3	2.3	1.1	3.7	2.7	1.7	3.0	2.2
Breast Cancer	0.1	0.2	0.6	0.5	-0.6	-0.5	-0.8	-0.1	0.3	0.2	0.6
Ovarian Cancer	1.9	2.5	4.5	-1.2	-1.8	0.7	-1.5	-2.1	-1.8	-0.9	-2.0
Prostate Cancer	0.7	0.9	2.0	-0.3	-1.3	-0.9	-0.9	-0.0	-1.4	0.2	-1.4
Age at First Birth	0.9	1.4	3.3	1.1	0.7	1.8	1.4	0.5	0.7	1.4	1.2
Bipolar Disorder (2011)	0.1	0.1	0.3	0.0	-0.5	0.6	-0.3	-0.1	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.4	0.5	1.6	1.1	0.3	0.6	1.3	-0.2	0.3	0.6	0.4
Coronary Artery Disease (CAD)	1.3	1.6	5.6	0.7	1.6	-0.1	1.1	1.6	2.4	0.2	0.0
Crohns Disease (2012)	0.6	0.9	2.4	1.1	1.5	0.6	0.7	0.3	1.5	-0.8	0.0
Mean Putamen Volume	1.4	1.6	5.6	1.3	2.1	-0.2	0.9	0.4	2.4	-0.0	0.4
Fasting Glucose	0.4	0.5	2.4	0.7	0.3	0.0	0.4	-0.6	0.1	-1.5	0.4
HbA1C	0.9	1.0	5.6	0.0	0.0	-0.5	0.6	2.4	0.7	1.2	-0.3
HDL Cholesterol	0.0	0.1	0.3	-0.6	-0.0	-0.1	0.2	-0.4	-0.2	-0.3	-0.2
LDL Cholesterol	0.3	0.5	2.2	-0.4	-0.0	0.1	0.4	1.5	0.5	0.9	-0.4
Lupus	0.4	0.6	2.4	-1.4	-0.2	-0.1	0.3	-1.5	0.2	-0.4	-0.1
Neuroticism (2016)	0.7	1.0	2.6	0.3	1.6	0.1	1.4	0.7	1.6	0.5	0.2
Primary Biliary Cirrhosis	0.6	0.8	1.9	0.4	0.5	-1.0	1.4	-0.4	0.0	-1.3	1.1
Rheumatoid Arthritis	0.3	0.4	1.2	-0.5	0.4	0.9	0.4	-1.1	0.3	-0.2	0.7
Schizophrenia (2014)	0.6	1.2	3.0	1.3	1.7	0.1	1.3	1.2	1.1	-0.7	-0.1
Triglycerides	0.8	1.4	3.9	-1.2	-1.4	0.1	-2.0	-0.7	-1.2	-0.7	-1.2
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.9	0.3	0.5	0.9	0.7	0.1	0.3	0.5	0.9
Ulcerative Colitis	0.2	0.3	0.8	0.6	0.6	-0.7	0.9	0.5	0.6	-0.3	0.2
Blood Eosinophil Count	0.5	3.8	10.3	0.7	1.9	1.3	1.9	2.4	1.8	3.2	1.4
Blood Platelet Count	0.3	3.7	14.7	1.8	-1.2	-2.1	-1.7	3.8	0.0	1.7	-0.3
Blood Red Count	1.0	10.0	19.2	2.0	2.7	3.0	3.1	3.1	3.2	4.4	3.4
Blood White Count	3.1	23.3	38.3	2.9	5.9	2.9	4.8	3.7	6.1	6.2	4.8
Heel T-Score	0.3	2.5	5.9	-0.6	-1.6	-0.1	-1.8	2.4	-1.6	1.9	-1.4
BMI	0.2	1.1	7.5	-0.4	-0.2	2.7	-0.4	-0.6	0.2	0.4	0.9
Height	0.3	6.1	23.3	0.9	4.8	2.5	2.5	-0.6	3.2	-0.4	1.2
Waist Hip Ratio (WHR)	0.1	0.6	1.2	-0.6	-0.9	0.3	-0.9	1.0	-0.9	0.1	-1.1
Systolic Blood Pressure	0.5	2.5	7.9	-0.9	-1.9	0.1	-0.4	-2.8	-2.2	-1.6	-0.2
Smoking Status	0.2	0.5	2.2	0.7	0.6	-1.5	-0.1	0.2	0.4	0.4	0.7
Allergy or Eczema	0.3	0.7	2.4	-1.6	0.1	0.4	0.0	-0.9	-0.0	-0.4	-1.3
Cardiovascular Disease	0.4	1.4	5.1	-0.0	0.6	2.3	0.9	-0.2	1.4	-0.6	1.6
Hypothyroidism (self reported)	1.2	2.8	8.6	0.1	1.1	-2.0	-0.6	-2.8	0.5	-2.9	0.1
Respiratory disease	0.4	1.0	3.9	-0.7	0.4	0.3	-2.0	-1.6	0.4	0.1	-0.7
Type 2 Diabetes (T2D) (2018)	1.3	2.5	5.0	2.0	1.6	-0.2	2.1	0.3	1.0	1.7	2.2
Lung FEV1/FVC ratio	4.5	23.0	37.7	-4.9	-6.0	-1.3	-5.7	-2.4	-6.1	-4.3	-5.3
Lung FVC	0.5	2.6	5.3	-1.5	-1.4	-2.1	-1.6	1.4	-1.3	-0.2	-2.3
Neuroticism	0.6	1.5	3.6	-1.9	-0.7	-1.6	-1.0	1.0	-0.5	-0.2	-1.7
Chronotype (morning person)	1.0	2.2	6.2	1.4	0.5	2.4	1.0	0.7	0.2	2.5	1.4
Hair Pigment	0.0	0.5	1.4	0.3	-0.4	1.2	-0.8	0.2	-0.8	0.7	0.7
Tanning	0.1	1.3	3.2	1.6	0.9	-1.8	1.0	0.3	0.8	-1.1	0.7
Hand grip strength (left)	0.1	0.4	1.1	0.9	0.4	-0.4	0.4	0.6	-0.1	1.1	0.2
Number of treatments/medications taken	0.6	1.1	3.2	-0.6	0.0	-1.3	-1.0	-1.8	0.2	-1.4	-0.4
Average weekly spirits intake	2.4	3.0	9.5	-1.2	-1.4	-3.1	-1.6	0.9	-1.2	-1.0	-2.3
Sensitivity / hurt feelings	0.5	0.9	3.2	-1.8	-0.6	0.7	-1.3	0.5	-0.5	-0.4	-1.0
Frequency of depressed mood in last 2 weeks	0.8	1.1	4.4	-0.1	-0.2	-2.1	0.1	1.3	-0.4	-0.1	-1.5
Hearing difficulty/problems: Yes	1.7	2.6	4.5	-1.9	-1.6	-0.4	-1.5	-2.1	-1.5	-2.1	-1.2
Relative age of first facial hair	0.2	0.5	1.7	-0.4	0.0	-0.3	-1.2	-1.3	-0.4	-0.4	-0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.8	-0.4	0.5	0.4	0.2	-0.3	0.7	-0.9	0.2
Ever used hormone-replacement therapy (HRT)	2.8	3.6	6.4	-1.7	-2.2	-0.5	-2.0	-2.1	-2.5	-1.4	-2.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	-0.2	-0.4	0.7	0.1	-0.5	-1.0	-0.7	-0.1
Systolic blood pressure, automated reading	0.8	2.4	5.5	-1.0	-1.5	-1.0	-0.5	-2.3	-2.0	-2.1	-1.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	0.1	-0.5	-0.9	0.5	0.5	-0.3	0.2	0.4
Angina	0.1	0.1	0.3	-0.5	0.2	0.1	-0.2	0.1	0.4	-0.5	-0.5
Medication for hormone replacement therapy	1.0	1.1	1.8	-0.9	-1.2	-0.9	-0.9	-1.3	-1.3	-0.4	-1.2
Vitamin and mineral supplements	0.8	1.1	2.4	1.5	0.7	0.7	1.2	0.6	0.8	1.0	1.6
Supplements: Zinc	1.0	1.1	2.4	-0.7	-1.3	-0.0	-1.5	-0.8	-1.0	-1.6	-0.4
Medication: Co-codamol	0.2	0.2	1.0	-0.1	-0.5	-0.0	0.2	0.2	-0.3	-1.0	-0.6
Medication: Metformin	1.2	1.7	3.8	0.9	1.4	0.5	1.5	0.7	2.0	0.7	1.9
Diabetes (father)	0.3	0.4	1.1	-0.6	-0.6	0.6	0.4	-0.3	-0.7	0.7	1.1
Diabetes (mother)	1.2	1.5	4.6	0.4	0.9	1.7	0.1	-2.1	0.3	0.3	1.8
Severe depression (siblings)	1.8	2.0	3.0	1.7	1.7	0.5	1.7	1.2	1.4	1.0	1.6
Pack years adult smoking proportion	0.3	0.4	1.8	-0.3	0.4	-1.3	0.6	-0.8	0.0	-0.3	0.2
Impedance of leg (right)	0.4	1.9	4.9	-0.8	-1.0	-1.0	-0.9	1.8	-0.4	2.2	-1.8
Leg fat-free mass (left)	0.6	3.0	7.3	0.7	2.1	2.7	1.9	-1.2	1.2	-1.1	2.1
Trunk fat percentage	0.4	1.7	6.8	0.1	1.3	2.6	0.5	0.4	1.5	1.5	0.8
Hand grip strength (right)	0.1	0.4	0.7	0.6	0.8	-0.3	0.7	0.8	0.4	0.7	-0.2
Townsend deprivation index at recruitment	0.9	1.3	3.9	0.7	1.3	-1.7	-0.5	0.8	2.0	0.1	0.5
Current tobacco smoking	1.6	2.7	6.3	2.1	2.1	-0.0	1.6	0.5	1.6	0.8	2.5
Average weekly fortified wine intake	1.2	1.4	3.9	-1.0	-1.0	-0.8	-2.0	1.1	-0.7	-0.3	-1.7
Maternal smoking around birth	0.2	0.3	0.9	-1.0	-0.5	-0.2	0.0	-0.1	-0.5	0.7	0.3
Fed-up feelings	0.3	0.6	1.4	0.0	-0.9	0.6	-0.8	-0.2	-1.2	0.5	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.8	-0.0	-1.3	-2.2	-1.1	1.5	-1.4	-0.2	-1.2
Relative age voice broke	0.4	0.6	1.3	-0.5	-0.6	-0.7	-1.1	-0.8	-1.0	-0.7	-0.1
Taking other prescription medications	1.0	1.6	7.5	0.1	1.0	-0.8	-0.2	-2.7	0.9	-1.5	0.5
Age when periods started (menarche)	0.2	0.4	0.8	-0.4	0.5	-0.9	0.6	-0.4	0.4	0.7	0.8
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.6	-0.7	-1.4	0.6	-1.2	-0.8	-1.5	-1.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	2.2	-0.4	-1.2	0.1	-1.0	1.0	-0.8	1.5	0.0
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	7.3	-0.1	1.2	-2.7	0.7	1.3	1.8	0.4	-0.9
Qualifications: CSEs or equivalent	0.7	0.9	2.5	-0.9	-0.2	1.6	0.1	-1.4	-0.2	0.5	1.3
Serious illness, injury or assault to yourself	0.3	0.4	2.2	1.5	0.4	-0.4	0.4	0.3	0.4	0.0	0.2
High blood pressure	0.9	2.6	4.4	-2.1	-1.9	1.4	-1.5	-1.4	-1.4	-2.0	-0.8
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.8	-2.2	-0.1	1.1	-0.6	-0.9	-0.4	-0.6	-1.6
Multivitamins +/- minerals	0.6	0.7	2.4	-1.5	-0.8	0.3	-0.7	-0.3	-0.8	-0.3	-1.2
Stomach or abdominal pain in last month	0.5	0.6	1.4	-0.3	1.0	0.9	1.2	-0.9	0.7	0.6	0.1
Supplements: Glucosamine	0.9	1.2	2.4	-0.6	-0.5	-0.8	-0.8	-1.5	-0.9	-1.4	-1.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	-0.7	-1.0	-0.4	-0.4	1.1	-0.7	0.3	-1.1
Medication: Atenolol	1.5	1.9	5.5	-1.0	-1.2	-0.9	-1.0	-2.4	-1.4	-1.4	-1.2
Medication: Levothyroxine sodium	1.5	2.6	7.0	0.4	-0.3	-1.6	-1.1	-2.6	-1.2	-2.6	-1.1
Sitting height	0.7	5.3	13.5	1.9	3.7	2.3	3.7	-0.1	1.9	-0.4	1.6
Chronic bronchitis/emphysema (father)	1.2	1.5	3.5	-0.3	1.2	0.0	1.9	0.8	0.8	1.9	1.3
High blood pressure (mother)	3.3	4.6	9.7	-2.2	-2.6	-0.5	-1.9	-2.6	-1.9	-3.1	-1.1
Body mass index (BMI)	0.3	1.1	7.4	-0.1	-0.1	2.7	0.0	-1.0	-0.1	-0.2	0.8
Impedance of leg (left)	0.6	2.7	6.6	-0.6	-1.1	-1.5	-0.8	2.5	-0.7	2.6	-2.0
Leg predicted mass (left)	0.5	2.8	6.5	0.7	2.0	2.5	1.8	-1.2	1.2	-1.2	2.0
Trunk fat mass	0.5	2.0	9.9	0.0	1.4	3.1	0.8	0.1	1.4	0.9	1.0
Waist circumference	0.3	0.9	7.0	-0.2	-0.0	2.6	-0.0	-0.3	-0.1	0.2	0.6
Number of incorrect matches in round	1.0	1.7	3.7	-1.5	-1.2	0.4	-1.4	-0.3	-1.3	-1.6	-1.9
Past tobacco smoking	0.2	0.4	2.0	-0.1	-0.1	1.4	0.1	-0.4	-0.2	-0.9	-0.0
Alcohol usually taken with meals	0.3	0.5	2.3	-0.9	-0.4	-0.1	-0.6	-0.4	-0.2	-0.6	-1.5
Nervous feelings	0.6	1.1	3.2	-1.4	-0.4	-0.5	-1.7	0.5	-0.1	-0.1	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-1.0	-0.2	-1.0	0.1	0.2	-0.2	-0.1	-0.5
Hearing difficulty/problems with background noise	0.3	0.5	1.5	0.4	1.2	-0.1	1.0	-0.6	0.7	-0.4	0.2
Hair/balding pattern: Pattern 2	0.2	0.2	0.6	0.6	0.7	0.1	0.8	-0.0	0.3	0.0	0.3
Had menopause	0.5	0.7	1.2	0.2	-1.0	-0.4	-1.1	0.6	-0.8	0.9	-1.1
Had other major operations	0.3	0.3	1.4	0.4	0.5	1.2	0.7	-0.1	0.4	0.5	-0.3
Forced vital capacity (FVC)	0.1	0.2	1.0	-0.1	0.3	-0.5	-0.2	1.0	-0.1	0.0	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	1.8	-1.0	-1.2	0.5	-1.1	-0.6	-1.3	0.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.7	-1.3	-0.1	-0.4	-0.2	-0.4	-0.1	-0.1	0.3
Qualifications: None of the above	0.8	1.7	6.2	0.2	-0.6	-2.3	-0.6	0.5	-0.7	-0.4	-2.5
Financial difficulties in last 2 years	0.6	0.7	3.3	-0.7	-0.8	1.8	-0.2	-0.8	-0.8	-0.5	0.0
Mouth/teeth dental problems	0.4	0.6	2.5	-1.6	-0.3	0.8	-0.4	0.4	-0.1	0.0	-1.3
Heart attack	0.6	0.7	2.0	-0.0	1.3	-0.4	-0.0	0.2	1.4	1.4	0.3
Allergy	0.3	0.8	2.6	1.6	-0.2	-0.7	0.8	0.6	-0.0	-0.2	1.4
Pain all over the body in last month	0.3	0.3	1.6	0.3	-0.5	0.2	-0.1	0.0	-0.5	1.3	0.5
Diabetes (self-reported)	0.3	0.5	2.2	0.3	0.2	0.0	1.2	0.2	0.2	0.7	1.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.8	-0.7	0.7	1.7	0.7	-0.4	0.5	0.2	0.1
Medication: Ramipril	0.0	0.0	0.1	0.2	-0.1	-0.2	-0.1	0.2	0.2	-0.2	-0.1
Medication: Simvastatin	0.2	0.3	0.7	0.6	0.6	-0.5	-0.3	0.0	0.8	0.7	0.6
Fluid intelligence score	1.8	3.7	7.4	1.7	1.9	0.7	2.7	2.2	1.1	2.7	1.2
Illnesses of siblings	0.7	0.9	3.0	0.5	0.1	1.0	1.2	1.7	-0.0	1.2	0.5
Neuroticism score	0.2	0.5	1.2	-1.1	-0.5	-0.2	-0.7	0.8	-0.2	-0.1	-1.1
Weight	0.4	2.0	11.0	0.1	1.3	3.3	1.1	-0.7	0.7	-0.3	1.1
Impedance of arm (right)	0.1	0.6	1.6	-0.7	1.0	0.1	-0.2	0.7	1.3	1.2	-0.2
Arm fat percentage (right)	0.4	1.4	8.8	-0.3	0.5	3.0	-0.0	-0.9	0.6	0.3	0.9
Trunk fat-free mass	0.3	1.8	4.9	0.3	1.3	2.2	1.6	-1.1	0.1	-1.8	0.9
Hip circumference	0.5	2.2	8.4	0.3	1.4	2.9	1.3	-0.8	1.2	0.0	1.8
Time employed in main current job	1.3	1.5	3.7	-0.9	-1.8	-0.4	-1.9	0.7	-1.4	0.7	-1.2
Alcohol intake versus 10 years previously	0.6	0.9	2.3	-0.4	-1.5	-0.5	-1.2	-0.3	-1.2	0.1	-1.1
Father’s age at death	1.4	1.9	3.6	-1.6	-1.2	0.7	-1.5	-1.9	-1.3	-1.6	-0.4
Worrier / anxious feelings	1.1	2.1	6.6	-1.4	-1.1	-0.9	-1.1	1.8	-0.9	-0.8	-2.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	0.6	0.4	-0.9	0.5	0.3	0.3	0.7	0.0
Falls in the last year	0.3	0.4	1.2	1.1	-0.5	-0.7	-0.2	0.7	-0.1	-0.5	-0.5
Hair/balding pattern: Pattern 3	2.2	3.2	6.2	-2.4	-2.5	0.3	-2.1	-0.3	-2.0	-0.7	-2.2
Number of live births	1.6	2.3	3.7	-0.5	-1.2	-1.5	-1.9	-1.9	-1.7	-1.9	-1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	4.9	-1.7	-1.9	-0.6	-2.0	0.6	-2.2	-0.6	-2.2
Pulse rate	1.4	2.4	10.7	0.2	1.4	3.3	1.5	-1.3	0.8	0.2	1.4
Happiness	1.0	1.2	3.1	1.6	0.6	-0.5	0.2	1.8	0.5	1.4	0.6
Noisy workplace	2.3	2.8	7.9	-1.4	-1.2	-2.4	-1.5	-1.0	-0.7	-2.8	-1.2
Qualifications: A levels/AS levels or equivalent	1.2	2.6	6.5	1.4	1.4	0.7	2.3	0.7	1.4	1.6	2.5
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.1	0.1	0.2	-0.5	-0.1	0.0	0.7	-1.1	-0.7
Mouth/teeth dental problems: Dentures	0.5	0.8	1.5	0.7	0.6	0.5	1.2	1.1	1.0	0.6	1.2
Asthma	0.4	0.8	3.2	-0.4	0.5	-0.8	-1.2	-1.8	0.4	-0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	4.1	1.9	1.3	0.9	1.0	1.4	1.7	2.0	1.6
Medication: Cholesterol lowering	0.4	0.6	2.4	-0.3	0.4	-1.1	-0.4	-1.0	1.5	-0.1	0.1
Depression (self-reported)	0.4	0.4	1.6	0.4	0.7	0.0	0.5	1.2	0.8	0.3	-0.5
Medication: Lansoprazole	0.3	0.4	1.7	-1.3	-0.3	0.2	-0.7	0.1	0.1	-0.5	-0.7
Prospective memory result	1.3	1.6	3.7	-1.9	-1.3	1.2	-1.8	-0.3	-1.0	-0.1	-1.2
Lung cancer (father)	0.3	0.3	0.9	-0.5	0.6	-0.5	-0.0	0.6	0.6	0.9	-0.5
Illnesses of mother	3.2	3.9	10.3	1.5	1.5	2.1	2.2	1.9	1.2	3.2	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	5.9	-1.9	-1.5	-0.2	-2.2	0.1	-1.6	-1.2	-2.4
Pulse wave Arterial Stiffness index	0.5	0.6	1.6	-0.6	-1.0	0.6	-1.3	-0.6	-0.9	-0.6	-0.4
Impedance of arm (left)	0.3	1.4	3.6	-0.3	1.4	0.7	0.2	1.1	1.8	1.9	0.4
Arm fat mass (right)	0.5	1.9	11.7	-0.2	0.7	3.4	0.5	-0.9	0.6	0.1	1.0
Trunk predicted mass	0.3	1.7	4.9	0.3	1.2	2.2	1.6	-1.1	0.0	-1.7	0.9
Standing height	0.3	2.6	8.8	0.4	3.0	1.9	2.3	0.4	1.6	-0.2	0.6
Length of working week for main job	0.1	0.1	0.2	0.3	-0.4	0.3	0.0	0.5	-0.1	0.2	0.2
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.0	0.2	0.4	0.5	-0.7	0.3	-0.8	0.0
Breastfed as a baby	0.9	1.1	4.5	-0.6	0.5	-2.1	1.1	0.2	0.2	-0.7	-1.3
Tense / ‘highly strung’	0.6	1.0	2.6	-1.6	-0.7	-1.3	-1.0	-0.5	-0.0	-0.7	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.2	0.7	1.5	-0.9	0.6	1.0	0.9	0.5	-0.5
Hair/balding pattern: Pattern 4	0.1	0.3	1.0	-0.8	-0.4	-0.3	-0.9	-1.0	0.0	0.0	0.2
Birth weight of first child	0.6	1.2	2.1	1.3	1.1	-1.2	0.8	1.4	1.4	-0.2	-0.3
Peak expiratory flow (PEF)	1.6	3.6	6.2	-2.4	-2.5	-0.7	-2.1	0.7	-2.4	0.8	-2.3
Pulse wave reflection index	1.5	1.8	4.3	-1.3	-1.6	-1.0	-1.5	-0.2	-1.4	-0.6	-2.1
Ever highly irritable/argumentative for 2 days	0.7	0.9	3.7	-1.9	-0.7	-0.5	-0.1	1.1	-0.1	-0.3	-1.1
Loud music exposure frequency	1.6	1.8	5.4	-1.1	-1.2	-0.6	-1.1	-1.9	-0.7	-2.3	-0.7
Qualifications: O levels/GCSEs or equivalent	3.2	5.1	11.6	2.4	2.5	0.9	3.3	0.2	2.0	1.1	3.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	4.8	1.1	0.2	0.1	-0.9	-2.2	-0.4	-0.7	1.0
Blood clot in the leg (DVT)	0.4	0.6	1.4	1.2	0.9	-0.3	0.2	0.8	0.4	0.9	0.7
Medication: Paracetamol	1.5	2.4	4.9	-1.8	-1.6	-1.9	-1.3	0.3	-1.4	-1.3	-2.2
Headache pain in last month	2.3	3.9	8.5	-1.8	-2.6	-0.4	-2.0	-0.5	-2.4	-1.6	-2.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	0.6	0.4	0.0	0.9	0.9	-0.7	1.1	-0.1
Glaucoma (self-reported)	3.4	4.0	8.8	2.3	2.4	1.0	3.0	1.2	2.1	1.7	1.8
Gout (self-reported)	0.7	0.9	1.8	-1.2	-1.2	0.0	-0.6	-1.1	-1.0	-0.3	-1.4
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	9.0	-0.3	0.2	-2.3	-1.3	-3.0	-0.6	-2.7	-0.5
Medication: Amlodipine	0.4	0.5	1.1	0.6	0.9	-0.8	0.3	-0.2	1.0	0.3	1.0
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.1	-1.2	-1.4	-0.6	-1.5	-1.8	-1.5	-0.8	-1.2
Birth weight	0.2	0.5	1.7	-0.3	-1.2	0.6	0.2	0.5	-1.3	0.0	0.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.1	-1.4	-0.5	-0.8	-1.3	-0.7	-0.4	-1.3	-1.1
High blood pressure (siblings)	1.0	1.5	5.8	0.4	0.2	-1.4	-1.5	-1.3	0.1	-2.4	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.7	2.7	-0.9	0.2	-0.2	-0.7	0.5	-0.1	-1.2	-1.6
Body fat percentage	0.3	1.1	6.4	-0.3	0.5	2.5	-0.0	0.2	0.9	1.2	0.4
Leg fat percentage (right)	0.4	1.3	4.2	-1.1	-1.4	2.1	-1.4	0.0	-0.8	0.3	-0.8
Arm fat-free mass (right)	0.3	1.3	4.0	0.7	1.1	2.0	1.7	-0.4	0.1	-0.6	1.2
Exposure to tobacco smoke outside home	0.4	0.6	3.9	0.1	0.2	-0.3	-0.0	-0.6	0.5	-2.0	0.4
Comparative body size at age 10	0.4	1.0	4.5	1.3	0.4	0.1	0.9	-0.3	0.4	0.5	2.1
Number of full brothers	1.0	1.2	3.8	1.9	1.3	0.2	1.4	0.8	0.9	-0.6	0.9
Worry too long after embarrassment	0.4	0.7	1.5	-1.0	0.7	0.9	0.8	0.4	1.0	1.2	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.9	0.7	1.4	-1.6	0.8	1.7	1.3	-0.4	-0.2
Wheeze or whistling in the chest in last year	0.3	0.5	3.3	-0.4	0.1	-1.8	-0.6	-0.6	0.1	-0.3	-0.4
Number of children fathered	3.3	3.7	5.0	2.2	1.9	1.3	2.2	1.7	1.6	2.2	2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.7	0.3	0.2	0.3	0.7	-0.4	-0.2	-0.7	0.8
Age at first live birth	0.2	0.4	1.2	0.8	0.8	-0.4	-0.1	0.6	0.3	0.5	1.1
Pulse wave peak to peak time	0.6	0.7	1.6	0.5	1.1	-0.4	1.3	0.7	1.0	0.9	0.5
Health satisfaction	1.1	1.4	3.0	1.6	1.5	-0.4	0.3	-1.3	1.7	-0.1	1.2
Shortness of breath walking on level ground	0.5	0.5	1.5	0.4	0.8	0.7	1.0	0.4	1.2	0.5	0.5
Qualifications: College or University degree	1.0	3.1	7.1	1.4	2.7	0.8	1.8	0.3	2.1	1.6	2.2
Eye problems/disorders: None of the above	0.3	0.4	1.7	-0.5	-0.2	-0.8	-0.5	-0.2	-0.2	-0.5	-1.3
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.3	0.9	-0.7	-1.5	-0.2	-0.0	-0.0	-0.6	1.1
Emphysema/chronic bronchitis	0.1	0.1	0.7	-0.0	-0.2	0.4	-0.3	0.1	0.8	0.4	0.2
Medication for pain relief, constipation, heartburn	0.4	0.6	1.8	0.6	0.6	1.0	1.4	0.1	-0.5	0.6	1.0
Neck or shoulder pain in last month	1.4	2.0	10.5	-0.5	-1.1	-3.2	-0.4	0.9	-0.5	-0.5	-1.5
Medication: Blood pressure	0.3	0.6	1.6	-1.2	-1.0	0.7	-0.6	-0.6	-0.2	-0.7	-0.7
Angina (self-reported)	0.1	0.2	0.6	-0.6	0.1	-0.2	-0.3	0.0	0.2	-0.7	-0.7
Migraine (self-reported)	0.5	0.6	2.4	0.1	-0.9	-0.2	-0.7	0.1	-0.6	-1.5	-0.8
Medication: Ibuprofen	1.4	1.7	4.2	2.1	1.3	-0.3	0.8	1.0	1.6	1.1	1.4
Medication: Allopurinol	0.2	0.3	1.3	-0.7	-0.2	-0.3	0.0	-0.6	-0.0	1.2	-0.4
Medication: Omeprazole	0.9	1.0	3.4	-0.7	-0.3	0.3	-0.8	-1.5	0.1	-1.9	-1.2
Medication: Seretide 50 evohaler	1.0	1.1	2.7	0.9	1.7	-0.1	1.1	0.2	1.6	1.1	0.8
Mean time to correctly identify matches	1.3	2.5	6.1	-1.0	-1.4	-0.9	-2.5	-0.8	-1.1	-2.0	-2.0
Heart disease (mother)	1.1	1.3	2.2	-0.4	-1.1	-1.2	-1.3	-0.8	-1.3	-1.5	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	3.8	-0.6	-0.6	-0.3	-0.6	-0.4	-0.3	1.9	0.2
Whole body fat mass	0.4	1.6	9.3	-0.2	1.0	3.0	0.5	-0.2	1.0	0.6	0.7
Leg fat mass (right)	0.2	0.9	6.8	-0.7	-0.3	2.6	-0.3	-0.2	0.0	0.2	0.0
Arm predicted mass (right)	0.3	1.5	4.0	0.6	1.2	2.0	1.9	-0.6	0.4	-0.8	1.3
Pulse rate, automated reading	0.2	0.7	1.8	0.5	1.0	1.1	0.6	0.6	1.4	-0.2	0.8
Alcohol intake frequency.	0.6	1.4	3.8	-1.1	-2.0	-0.4	-0.4	-1.1	-1.4	-1.0	-1.4
Comparative height size at age 10	0.3	1.7	4.4	-0.8	2.1	2.1	1.6	0.1	1.0	-0.7	-0.5
Number of full sisters	1.0	1.3	2.7	1.4	1.6	-0.1	1.0	-1.2	0.6	0.3	1.7
Suffer from ‘nerves’	0.3	0.4	1.0	-0.4	0.1	0.6	-0.0	1.0	0.7	1.0	-0.6
Overall health rating	0.1	0.2	0.7	-0.2	-0.2	-0.2	0.1	-0.8	0.4	-0.8	-0.1
Chest pain or discomfort	0.1	0.2	0.8	-0.6	0.4	-0.2	0.9	0.1	0.5	0.1	0.2
Had major operations	0.6	0.7	1.6	-0.9	-0.5	1.3	-0.8	-0.8	-0.2	-0.7	-0.9
Age at last live birth	0.5	0.7	3.3	1.2	0.6	-0.1	-0.2	-0.3	0.2	0.2	1.8
Family relationship satisfaction	0.7	0.8	3.3	1.5	0.7	-0.3	-0.2	0.3	0.4	0.4	1.8
Leg pain on walking	1.9	2.4	4.9	-2.2	-1.6	-0.4	-1.8	-1.3	-1.4	-1.0	-2.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.9	-0.8	-0.2	1.7	0.6	-0.1	0.4	-0.4	0.8
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.9	1.1	0.5	1.4	0.7	-1.1	-0.5	0.2	1.3
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.1	0.9	0.7	-0.4	0.5	0.2	-0.0	1.0	1.0
Medication: Aspirin	0.4	0.5	1.3	0.1	0.3	-0.1	-0.7	1.0	1.1	1.1	0.2
Supplements: Vitamin C	0.2	0.3	1.1	-0.3	-0.2	-0.6	-1.0	0.1	0.1	-0.2	-0.6
Knee pain experienced in last month	0.7	1.1	3.0	0.1	-1.2	1.1	-1.7	0.1	-1.4	-0.7	-0.8
Hypertension (Self-reported)	0.5	1.3	2.5	-1.5	-1.3	1.0	-0.8	-1.5	-0.7	-1.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	5.8	-0.3	0.2	-2.2	-1.2	-0.8	0.4	-2.4	-0.9
Illnesses of father: Heart disease	1.3	1.8	7.6	-1.1	-0.7	-2.8	-1.6	-0.7	-0.2	-0.7	-1.4
Illnesses of siblings: Diabetes	0.3	0.4	0.8	-0.4	-0.9	0.8	-0.8	0.6	-0.6	0.7	-0.3
Smoking status: Previous	0.7	1.0	2.2	-0.7	-1.2	-1.5	-1.3	0.2	-0.9	0.0	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.8	0.0	1.3	0.0	0.9	0.3	1.2	0.9	0.5
Whole body fat-free mass	0.4	2.3	5.6	0.6	1.6	2.4	1.9	-1.2	0.5	-1.4	1.5
Leg fat-free mass (right)	0.6	3.0	5.4	1.1	2.2	2.3	2.1	-1.0	1.3	-1.0	2.2
Arm fat percentage (left)	0.4	1.7	9.8	-0.2	0.7	3.1	0.2	-0.6	1.0	0.5	1.1
Average weekly red wine intake	1.2	1.8	4.9	-1.8	-0.6	0.9	-1.0	-2.2	-0.7	-1.4	-1.4
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	-0.1	-0.1	-0.6	-0.6	1.1	0.4	0.4	0.1
Mood swings	0.2	0.3	1.2	-0.7	-0.6	0.6	0.1	0.1	-1.1	0.4	0.2
Loneliness, isolation	0.5	0.7	2.5	-0.2	0.1	-1.4	-0.7	0.6	0.5	1.6	0.6
Long-standing illness, disability or infirmity	0.5	0.8	2.5	-1.3	-0.3	0.2	-0.2	-1.6	0.1	-1.2	-0.6
Ever had bowel cancer screening	0.8	1.0	2.5	-0.2	0.5	-1.6	0.3	1.5	0.8	1.1	-0.9
Diabetes diagnosed by doctor	0.3	0.4	1.6	0.1	0.2	-0.1	1.3	0.3	0.2	0.6	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.7	0.8	0.4	0.8	-0.4	-0.0	0.3	0.2	1.6
Friendships satisfaction	0.5	0.6	1.2	0.8	0.9	-0.6	0.2	-1.1	0.7	0.6	1.1
Qualifications: nursing, teaching	0.9	1.5	3.5	1.7	1.1	1.4	0.5	-1.4	-0.2	0.2	1.9
Commuting to job workplace: Walk	1.6	1.7	10.6	-0.5	-0.4	-3.2	-0.6	0.1	0.5	-1.3	-0.6
Eye problems/disorders: Cataract	1.8	2.1	6.6	1.5	1.5	0.7	1.2	0.8	1.5	0.9	2.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.0	0.2	-1.0	-1.4	-1.0	-0.8	-0.9	-0.5	0.0
Medication for cholesterol	0.7	1.1	4.7	0.2	0.7	1.0	0.6	2.2	1.2	0.8	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	7.5	0.7	0.7	-2.7	-0.1	1.0	1.3	-1.8	-0.2
Back pain experienced in last month	0.1	0.2	0.5	0.7	0.4	-0.1	0.0	0.3	0.2	-0.4	-0.7
Mineral and other dietary supplements	3.9	5.3	12.5	2.3	2.2	0.9	2.3	1.7	2.3	2.3	3.5
Breast cancer (self-reported)	1.1	1.3	3.1	-0.3	1.5	0.6	1.8	-1.5	1.2	-0.8	0.5
Asthma (self-reported)	0.5	0.9	4.0	-0.7	0.4	-0.7	-1.3	-2.0	0.3	-0.2	-0.7
Osteoporosis (self-reported)	0.3	0.3	0.9	0.7	0.3	-0.5	-0.8	0.2	0.7	0.9	0.1
Osteoarthritis (self-reported)	1.9	2.4	4.9	-1.7	-2.2	0.2	-2.0	-0.0	-1.7	-0.9	-1.9
Medication: Aspirin	0.4	0.5	1.8	0.1	0.4	-0.2	-0.6	0.9	1.1	1.4	-0.1
Medication: Gliclazide	0.2	0.2	0.6	-0.0	-0.8	-0.6	0.4	0.7	-0.5	-0.2	0.2
Illnesses of father: None of the above (group 1)	1.1	1.3	5.3	1.3	0.9	2.3	0.5	0.9	0.8	0.8	0.6
Smoking status: Current	1.7	2.8	7.1	2.1	2.1	-0.1	1.8	0.4	1.5	0.9	2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.4	-1.5	-1.6	-0.9	-2.1	0.2	-2.1	-0.4	-2.0
Whole body water mass	0.4	2.5	6.1	0.6	1.7	2.5	1.9	-1.3	0.6	-1.5	1.6
Leg predicted mass (right)	0.6	3.2	5.4	1.1	2.3	2.3	2.1	-1.0	1.3	-1.0	2.3
Arm fat mass (left)	0.4	1.8	12.1	-0.4	0.6	3.5	0.2	-0.9	0.6	-0.0	0.8
Number of self-reported non-cancer illnesses	0.6	1.1	2.8	-0.7	0.7	-1.0	-1.0	-1.3	0.9	-1.7	-0.6
Average weekly champagne plus white wine intake	0.6	0.9	1.8	1.3	1.0	-0.6	1.2	-0.9	0.6	-0.6	0.9
Miserableness	0.2	0.3	1.0	0.3	-0.3	-1.0	-0.3	-0.2	-0.5	-0.5	-0.9
Guilty feelings	0.8	1.2	2.2	0.5	1.1	-1.2	0.9	1.2	1.3	1.5	0.7
Wears glasses or contact lenses	2.3	2.6	6.4	-2.5	-1.8	2.2	-1.4	-0.9	-0.9	-0.8	-1.4
Ever taken oral contraceptive pill	2.2	2.5	4.3	1.4	2.1	1.4	1.6	-1.3	1.3	1.8	1.6
Hearing aid user	2.9	3.3	5.9	-1.8	-1.4	-0.6	-1.9	-2.1	-1.9	-2.4	-1.7
Mother’s age at death	0.3	0.4	2.1	-0.2	-0.1	0.8	-0.1	0.9	-0.0	1.4	-0.1
Financial situation satisfaction	1.1	1.3	2.2	-1.1	-1.3	-1.5	-1.1	-1.5	-0.8	-1.3	0.0
Tinnitus: Yes, now most or all of the time	2.9	3.4	6.9	-2.4	-2.3	0.1	-2.6	-0.3	-2.2	-0.5	-2.0
Commuting to job workplace: Public transport	0.4	0.4	1.7	-0.6	0.3	-0.6	0.6	1.3	0.7	0.3	-0.1
Eye problems/disorders: Glaucoma	3.3	3.9	8.7	2.6	2.3	0.3	2.9	1.2	2.2	1.7	1.1
Medication: Blood pressure	0.4	0.8	4.0	-0.3	-0.1	-0.1	0.5	-2.0	-0.4	-1.2	0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.9	0.6	-0.1	-1.4	-1.3	-0.3	-0.7	-0.9	-1.4
Supplements: Fish oil (including cod liver oil)	1.9	2.4	5.5	-1.8	-1.6	-0.3	-1.7	-0.7	-1.6	-1.3	-2.3
High cholesterol (Self-reported)	0.3	0.6	2.7	-0.1	1.1	0.6	-0.6	-0.2	1.6	0.2	0.5
Medication: Bendroflumethiazide	0.7	1.0	3.2	-1.2	-1.0	0.7	-0.0	-1.8	-1.2	-0.3	-0.6
Medication: Paracetamol	1.5	2.3	4.7	-1.7	-1.3	-2.1	-1.2	0.0	-1.0	-1.6	-2.2
Medication: Lisinopril	0.2	0.3	0.8	-0.9	-0.5	0.8	-0.8	0.2	-0.2	0.2	0.1
Medication: Atorvastatin	0.2	0.2	0.5	-0.2	0.4	-0.2	-0.3	-0.6	0.7	-0.2	0.5
Illnesses of father: High blood pressure	1.1	1.3	2.9	-1.7	-1.1	0.3	-0.9	-1.3	-1.1	-1.6	-0.2
Alcohol drinker status: Never	0.7	0.8	3.6	0.4	0.6	-1.0	-0.2	-0.9	0.4	-1.9	0.6
Ever smoked	0.7	1.2	3.0	1.1	1.2	0.1	0.9	0.3	1.1	1.7	1.4
Basal metabolic rate	0.4	2.4	7.5	0.6	1.7	2.7	1.8	-1.1	0.7	-1.1	1.5
Leg fat percentage (left)	0.3	1.2	3.3	-0.8	-1.4	1.8	-1.3	0.5	-0.8	0.6	-0.8
Arm fat-free mass (left)	0.3	1.4	4.8	0.2	1.0	2.2	1.6	-1.0	-0.0	-1.0	0.8
Number of operations (self-reported)	0.2	0.4	2.0	-0.0	0.1	1.4	0.1	0.3	0.6	-0.0	-0.6
Average weekly beer plus cider intake	0.6	0.9	3.9	0.3	-0.4	0.1	-0.0	2.0	-0.3	1.6	0.7
Irritability	0.4	0.7	3.3	-1.8	-0.8	0.6	-0.1	0.1	-0.6	-0.5	-0.7
Risk taking	0.6	0.9	3.0	-0.1	0.3	1.7	0.3	-1.3	0.3	-0.7	1.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.9	-0.1	0.6	-0.2	-1.2	-0.1	0.7	-1.7	-0.6
Fractured/broken bones in last 5 years	0.9	1.2	4.8	0.9	0.1	-0.8	0.4	-1.8	-0.0	-2.2	0.2
Age started oral contraceptive pill	1.1	1.4	3.8	0.1	0.9	-0.9	1.4	1.6	0.8	2.0	-0.2
Diastolic blood pressure, automated reading	0.5	1.5	3.4	-1.2	-1.2	0.5	-0.8	-1.6	-1.1	-1.8	-0.9
Ever depressed for a whole week	0.3	0.3	1.7	-1.3	-0.6	0.3	-0.1	0.0	-0.4	0.6	-0.4
Unable to work because of sickness or disability	0.9	1.1	2.6	0.9	1.4	0.3	1.6	0.8	1.3	0.7	0.8
Commuting to job workplace: Cycle	1.0	1.2	5.6	0.7	1.1	-2.4	-0.1	-0.7	0.9	-0.8	0.8
Myopia	0.4	0.6	2.0	0.6	0.2	-1.4	-0.9	-1.0	0.2	-0.5	0.0
Vascular/heart problems diagnosed by doctor	0.8	2.2	3.9	2.0	1.8	-1.7	1.3	1.4	1.4	1.5	0.5
Cholesterol lowering medication	0.2	0.3	0.8	0.9	0.6	-0.9	0.4	0.4	0.1	0.3	0.6
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	4.6	-1.0	-0.2	-0.0	-1.2	-1.9	0.1	-2.1	-1.3
Pain experienced in last month	0.6	1.0	2.3	0.0	0.6	0.8	1.4	0.6	0.9	1.3	1.5
Supplements: Calcium	1.0	1.1	3.0	0.5	-0.1	-1.6	-1.0	-1.7	-0.4	-1.1	-1.0
Basal cell carcinoma (self-reported)	0.4	0.4	0.7	-0.7	-0.8	0.5	-0.8	-0.5	-0.8	-0.4	-0.6
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.7	-0.0	1.5	-0.3	0.3	0.2	1.5	1.6	0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.3	1.2	0.9	0.1	0.2	0.7	0.4	1.0	0.7
Heart disease (siblings)	0.7	0.8	1.5	-0.9	-0.7	-0.2	-0.1	-1.1	-1.2	-1.2	-1.1
Alcohol drinker status: Previous	0.3	0.4	1.8	0.2	0.2	1.4	0.8	-0.5	0.1	0.4	0.2
Pack years of smoking	0.3	0.4	2.6	-0.6	0.2	-1.6	0.4	-0.3	0.0	-0.2	-0.3
Impedance of whole body	0.3	1.7	6.7	-0.3	0.5	-0.9	-0.2	2.1	0.8	2.6	-0.9
Leg fat mass (left)	0.2	0.8	5.9	-0.5	-0.1	2.4	-0.1	0.0	0.2	0.3	0.1
Arm predicted mass (left)	0.2	1.2	3.9	0.4	0.9	2.0	1.5	-0.8	-0.0	-1.0	1.0