Hub : Genes

ADAM33

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.2550 0.0770 6.0e-04 0.093 NA 0.097 NA 0.133 7.9e-06 NA 5.5e-06 NA 8.8e-08
2 GTEx Artery Tibial 0.3188 0.0693 2.9e-06 0.102 NA 0.108 NA 0.112 2.3e-08 NA 9.0e-09 NA 4.8e-09
3 GTEx Esophagus Mucosa 0.1420 0.0480 1.4e-03 0.041 NA 0.011 NA 0.023 9.6e-04 NA 5.4e-02 NA 1.1e-02
4 GTEx Nerve Tibial 0.2462 0.0779 6.2e-03 0.016 NA 0.062 NA 0.038 2.4e-02 NA 3.3e-05 NA 1.0e-03
5 ROSMAP Brain Pre-frontal Cortex 0.1952 0.0399 1.4e-09 0.019 0.097 0.130 0.109 0.116 1.5e-03 2.1e-12 2.1e-16 7.5e-14 1.1e-14
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0691 0.0253 4.7e-05 0.025 0.040 0.041 NA 0.038 6.4e-04 2.2e-05 1.9e-05 NA 4.0e-05
7 TCGA Lung Adenocarcinoma 0.0536 0.0210 8.7e-05 0.024 0.037 0.023 NA 0.026 7.5e-04 2.9e-05 9.2e-04 NA 4.3e-04
8 TCGA Lung Squamous Cell Carcinoma 0.0612 0.0242 1.5e-04 0.023 0.030 0.024 NA 0.019 1.1e-03 2.3e-04 8.7e-04 NA 2.7e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.3 3.2 -0.9 -1.1 0.1 -1.8 -0.7 -0.9 -1.8 -0.8
Bipolar Disorder or Schizophrenia 0.2 0.5 1.5 0.8 1.1 -0.1 0.2 0.1 0.6 -1.2 -0.4
Depressed Affect (Nagel 2018) 0.2 0.5 2.4 0.6 0.3 -0.4 0.7 0.7 -0.2 1.5 -0.1
Depression (Nagel 2018) 1.0 1.5 4.6 -0.0 -0.7 -2.0 -0.3 1.5 -0.8 -0.1 -2.1
Intelligence (Savage-Jansen 2018) 0.8 2.6 5.7 1.4 1.5 -0.8 2.4 2.1 1.3 1.7 1.0
Neuroticism (Nagel 2018) 0.2 0.5 1.4 -0.6 0.1 -0.0 0.2 1.2 0.1 1.0 -1.0
Schizophrenia (2018) 1.0 2.1 6.5 1.8 2.6 -0.2 1.7 0.6 1.8 -0.1 0.2
Schizophrenia vs Biploar Disorder 1.3 1.8 4.8 1.7 2.2 0.9 1.7 0.7 1.5 0.1 0.4
Worry (Nagel 2018) 0.9 1.9 5.4 -1.4 -0.9 -1.6 -1.3 1.5 -0.5 -0.5 -2.3
Alzheimer’s Disease (in mother) 1.2 1.4 8.1 -0.2 -0.5 -2.8 -0.3 -0.6 -0.3 -1.6 -0.3
Alzheimer’s Disease (in father) 0.8 0.9 2.9 -1.0 -0.8 -0.7 -0.5 -0.2 -0.8 -1.1 -1.7
Alzheimer’s Disease (including proxy) 0.6 0.8 4.0 -0.1 -0.2 -2.0 -0.1 -0.2 0.1 -1.5 -0.7
Crohns Disease (2017) 0.9 1.9 4.2 2.0 1.5 -1.4 0.9 1.4 1.8 0.3 0.9
Irritable Bowel Disease (IBD) 0.4 0.9 2.8 1.5 0.7 -1.7 0.0 0.6 0.9 -0.4 0.6
Ulcerative Colitis (UC) 0.2 0.3 1.2 0.1 -0.6 -1.1 -0.8 0.3 -0.2 -0.4 0.1
Major Depression (MDD) 0.2 0.3 1.6 0.0 0.0 0.5 0.4 0.5 0.0 1.3 0.0
Reaction Time 0.2 0.5 1.5 0.3 -0.1 -1.0 -0.9 -0.5 -0.2 -1.2 -0.1
Verbal and Numeric Reasoning (VNR) 2.6 6.3 13.8 2.3 2.3 1.1 3.7 2.7 1.7 3.0 2.2
Breast Cancer 0.1 0.2 0.6 0.5 -0.6 -0.5 -0.8 -0.1 0.3 0.2 0.6
Ovarian Cancer 1.9 2.5 4.5 -1.2 -1.8 0.7 -1.5 -2.1 -1.8 -0.9 -2.0
Prostate Cancer 0.7 0.9 2.0 -0.3 -1.3 -0.9 -0.9 -0.0 -1.4 0.2 -1.4
Age at First Birth 0.9 1.4 3.3 1.1 0.7 1.8 1.4 0.5 0.7 1.4 1.2
Bipolar Disorder (2011) 0.1 0.1 0.3 0.0 -0.5 0.6 -0.3 -0.1 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 1.6 1.1 0.3 0.6 1.3 -0.2 0.3 0.6 0.4
Coronary Artery Disease (CAD) 1.3 1.6 5.6 0.7 1.6 -0.1 1.1 1.6 2.4 0.2 0.0
Crohns Disease (2012) 0.6 0.9 2.4 1.1 1.5 0.6 0.7 0.3 1.5 -0.8 0.0
Mean Putamen Volume 1.4 1.6 5.6 1.3 2.1 -0.2 0.9 0.4 2.4 -0.0 0.4
Fasting Glucose 0.4 0.5 2.4 0.7 0.3 0.0 0.4 -0.6 0.1 -1.5 0.4
HbA1C 0.9 1.0 5.6 0.0 0.0 -0.5 0.6 2.4 0.7 1.2 -0.3
HDL Cholesterol 0.0 0.1 0.3 -0.6 -0.0 -0.1 0.2 -0.4 -0.2 -0.3 -0.2
LDL Cholesterol 0.3 0.5 2.2 -0.4 -0.0 0.1 0.4 1.5 0.5 0.9 -0.4
Lupus 0.4 0.6 2.4 -1.4 -0.2 -0.1 0.3 -1.5 0.2 -0.4 -0.1
Neuroticism (2016) 0.7 1.0 2.6 0.3 1.6 0.1 1.4 0.7 1.6 0.5 0.2
Primary Biliary Cirrhosis 0.6 0.8 1.9 0.4 0.5 -1.0 1.4 -0.4 0.0 -1.3 1.1
Rheumatoid Arthritis 0.3 0.4 1.2 -0.5 0.4 0.9 0.4 -1.1 0.3 -0.2 0.7
Schizophrenia (2014) 0.6 1.2 3.0 1.3 1.7 0.1 1.3 1.2 1.1 -0.7 -0.1
Triglycerides 0.8 1.4 3.9 -1.2 -1.4 0.1 -2.0 -0.7 -1.2 -0.7 -1.2
Type 2 Diabetes (T2D) (2012) 0.3 0.4 0.9 0.3 0.5 0.9 0.7 0.1 0.3 0.5 0.9
Ulcerative Colitis 0.2 0.3 0.8 0.6 0.6 -0.7 0.9 0.5 0.6 -0.3 0.2
Blood Eosinophil Count 0.5 3.8 10.3 0.7 1.9 1.3 1.9 2.4 1.8 3.2 1.4
Blood Platelet Count 0.3 3.7 14.7 1.8 -1.2 -2.1 -1.7 3.8 0.0 1.7 -0.3
Blood Red Count 1.0 10.0 19.2 2.0 2.7 3.0 3.1 3.1 3.2 4.4 3.4
Blood White Count 3.1 23.3 38.3 2.9 5.9 2.9 4.8 3.7 6.1 6.2 4.8
Heel T-Score 0.3 2.5 5.9 -0.6 -1.6 -0.1 -1.8 2.4 -1.6 1.9 -1.4
BMI 0.2 1.1 7.5 -0.4 -0.2 2.7 -0.4 -0.6 0.2 0.4 0.9
Height 0.3 6.1 23.3 0.9 4.8 2.5 2.5 -0.6 3.2 -0.4 1.2
Waist Hip Ratio (WHR) 0.1 0.6 1.2 -0.6 -0.9 0.3 -0.9 1.0 -0.9 0.1 -1.1
Systolic Blood Pressure 0.5 2.5 7.9 -0.9 -1.9 0.1 -0.4 -2.8 -2.2 -1.6 -0.2
Smoking Status 0.2 0.5 2.2 0.7 0.6 -1.5 -0.1 0.2 0.4 0.4 0.7
Allergy or Eczema 0.3 0.7 2.4 -1.6 0.1 0.4 0.0 -0.9 -0.0 -0.4 -1.3
Cardiovascular Disease 0.4 1.4 5.1 -0.0 0.6 2.3 0.9 -0.2 1.4 -0.6 1.6
Hypothyroidism (self reported) 1.2 2.8 8.6 0.1 1.1 -2.0 -0.6 -2.8 0.5 -2.9 0.1
Respiratory disease 0.4 1.0 3.9 -0.7 0.4 0.3 -2.0 -1.6 0.4 0.1 -0.7
Type 2 Diabetes (T2D) (2018) 1.3 2.5 5.0 2.0 1.6 -0.2 2.1 0.3 1.0 1.7 2.2
Lung FEV1/FVC ratio 4.5 23.0 37.7 -4.9 -6.0 -1.3 -5.7 -2.4 -6.1 -4.3 -5.3
Lung FVC 0.5 2.6 5.3 -1.5 -1.4 -2.1 -1.6 1.4 -1.3 -0.2 -2.3
Neuroticism 0.6 1.5 3.6 -1.9 -0.7 -1.6 -1.0 1.0 -0.5 -0.2 -1.7
Chronotype (morning person) 1.0 2.2 6.2 1.4 0.5 2.4 1.0 0.7 0.2 2.5 1.4
Hair Pigment 0.0 0.5 1.4 0.3 -0.4 1.2 -0.8 0.2 -0.8 0.7 0.7
Tanning 0.1 1.3 3.2 1.6 0.9 -1.8 1.0 0.3 0.8 -1.1 0.7
Hand grip strength (left) 0.1 0.4 1.1 0.9 0.4 -0.4 0.4 0.6 -0.1 1.1 0.2
Number of treatments/medications taken 0.6 1.1 3.2 -0.6 0.0 -1.3 -1.0 -1.8 0.2 -1.4 -0.4
Average weekly spirits intake 2.4 3.0 9.5 -1.2 -1.4 -3.1 -1.6 0.9 -1.2 -1.0 -2.3
Sensitivity / hurt feelings 0.5 0.9 3.2 -1.8 -0.6 0.7 -1.3 0.5 -0.5 -0.4 -1.0
Frequency of depressed mood in last 2 weeks 0.8 1.1 4.4 -0.1 -0.2 -2.1 0.1 1.3 -0.4 -0.1 -1.5
Hearing difficulty/problems: Yes 1.7 2.6 4.5 -1.9 -1.6 -0.4 -1.5 -2.1 -1.5 -2.1 -1.2
Relative age of first facial hair 0.2 0.5 1.7 -0.4 0.0 -0.3 -1.2 -1.3 -0.4 -0.4 -0.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.8 -0.4 0.5 0.4 0.2 -0.3 0.7 -0.9 0.2
Ever used hormone-replacement therapy (HRT) 2.8 3.6 6.4 -1.7 -2.2 -0.5 -2.0 -2.1 -2.5 -1.4 -2.0
Ever had hysterectomy (womb removed) 0.3 0.3 1.0 -0.2 -0.4 0.7 0.1 -0.5 -1.0 -0.7 -0.1
Systolic blood pressure, automated reading 0.8 2.4 5.5 -1.0 -1.5 -1.0 -0.5 -2.3 -2.0 -2.1 -1.0
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.9 0.1 -0.5 -0.9 0.5 0.5 -0.3 0.2 0.4
Angina 0.1 0.1 0.3 -0.5 0.2 0.1 -0.2 0.1 0.4 -0.5 -0.5
Medication for hormone replacement therapy 1.0 1.1 1.8 -0.9 -1.2 -0.9 -0.9 -1.3 -1.3 -0.4 -1.2
Vitamin and mineral supplements 0.8 1.1 2.4 1.5 0.7 0.7 1.2 0.6 0.8 1.0 1.6
Supplements: Zinc 1.0 1.1 2.4 -0.7 -1.3 -0.0 -1.5 -0.8 -1.0 -1.6 -0.4
Medication: Co-codamol 0.2 0.2 1.0 -0.1 -0.5 -0.0 0.2 0.2 -0.3 -1.0 -0.6
Medication: Metformin 1.2 1.7 3.8 0.9 1.4 0.5 1.5 0.7 2.0 0.7 1.9
Diabetes (father) 0.3 0.4 1.1 -0.6 -0.6 0.6 0.4 -0.3 -0.7 0.7 1.1
Diabetes (mother) 1.2 1.5 4.6 0.4 0.9 1.7 0.1 -2.1 0.3 0.3 1.8
Severe depression (siblings) 1.8 2.0 3.0 1.7 1.7 0.5 1.7 1.2 1.4 1.0 1.6
Pack years adult smoking proportion 0.3 0.4 1.8 -0.3 0.4 -1.3 0.6 -0.8 0.0 -0.3 0.2
Impedance of leg (right) 0.4 1.9 4.9 -0.8 -1.0 -1.0 -0.9 1.8 -0.4 2.2 -1.8
Leg fat-free mass (left) 0.6 3.0 7.3 0.7 2.1 2.7 1.9 -1.2 1.2 -1.1 2.1
Trunk fat percentage 0.4 1.7 6.8 0.1 1.3 2.6 0.5 0.4 1.5 1.5 0.8
Hand grip strength (right) 0.1 0.4 0.7 0.6 0.8 -0.3 0.7 0.8 0.4 0.7 -0.2
Townsend deprivation index at recruitment 0.9 1.3 3.9 0.7 1.3 -1.7 -0.5 0.8 2.0 0.1 0.5
Current tobacco smoking 1.6 2.7 6.3 2.1 2.1 -0.0 1.6 0.5 1.6 0.8 2.5
Average weekly fortified wine intake 1.2 1.4 3.9 -1.0 -1.0 -0.8 -2.0 1.1 -0.7 -0.3 -1.7
Maternal smoking around birth 0.2 0.3 0.9 -1.0 -0.5 -0.2 0.0 -0.1 -0.5 0.7 0.3
Fed-up feelings 0.3 0.6 1.4 0.0 -0.9 0.6 -0.8 -0.2 -1.2 0.5 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.3 1.7 4.8 -0.0 -1.3 -2.2 -1.1 1.5 -1.4 -0.2 -1.2
Relative age voice broke 0.4 0.6 1.3 -0.5 -0.6 -0.7 -1.1 -0.8 -1.0 -0.7 -0.1
Taking other prescription medications 1.0 1.6 7.5 0.1 1.0 -0.8 -0.2 -2.7 0.9 -1.5 0.5
Age when periods started (menarche) 0.2 0.4 0.8 -0.4 0.5 -0.9 0.6 -0.4 0.4 0.7 0.8
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 2.6 -0.7 -1.4 0.6 -1.2 -0.8 -1.5 -1.6 -1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 2.2 -0.4 -1.2 0.1 -1.0 1.0 -0.8 1.5 0.0
Tinnitus: Yes, but not now, but have in the past 1.8 1.9 7.3 -0.1 1.2 -2.7 0.7 1.3 1.8 0.4 -0.9
Qualifications: CSEs or equivalent 0.7 0.9 2.5 -0.9 -0.2 1.6 0.1 -1.4 -0.2 0.5 1.3
Serious illness, injury or assault to yourself 0.3 0.4 2.2 1.5 0.4 -0.4 0.4 0.3 0.4 0.0 0.2
High blood pressure 0.9 2.6 4.4 -2.1 -1.9 1.4 -1.5 -1.4 -1.4 -2.0 -0.8
Hayfever, allergic rhinitis or eczema 0.6 1.3 4.8 -2.2 -0.1 1.1 -0.6 -0.9 -0.4 -0.6 -1.6
Multivitamins +/- minerals 0.6 0.7 2.4 -1.5 -0.8 0.3 -0.7 -0.3 -0.8 -0.3 -1.2
Stomach or abdominal pain in last month 0.5 0.6 1.4 -0.3 1.0 0.9 1.2 -0.9 0.7 0.6 0.1
Supplements: Glucosamine 0.9 1.2 2.4 -0.6 -0.5 -0.8 -0.8 -1.5 -0.9 -1.4 -1.6
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.3 -0.7 -1.0 -0.4 -0.4 1.1 -0.7 0.3 -1.1
Medication: Atenolol 1.5 1.9 5.5 -1.0 -1.2 -0.9 -1.0 -2.4 -1.4 -1.4 -1.2
Medication: Levothyroxine sodium 1.5 2.6 7.0 0.4 -0.3 -1.6 -1.1 -2.6 -1.2 -2.6 -1.1
Sitting height 0.7 5.3 13.5 1.9 3.7 2.3 3.7 -0.1 1.9 -0.4 1.6
Chronic bronchitis/emphysema (father) 1.2 1.5 3.5 -0.3 1.2 0.0 1.9 0.8 0.8 1.9 1.3
High blood pressure (mother) 3.3 4.6 9.7 -2.2 -2.6 -0.5 -1.9 -2.6 -1.9 -3.1 -1.1
Body mass index (BMI) 0.3 1.1 7.4 -0.1 -0.1 2.7 0.0 -1.0 -0.1 -0.2 0.8
Impedance of leg (left) 0.6 2.7 6.6 -0.6 -1.1 -1.5 -0.8 2.5 -0.7 2.6 -2.0
Leg predicted mass (left) 0.5 2.8 6.5 0.7 2.0 2.5 1.8 -1.2 1.2 -1.2 2.0
Trunk fat mass 0.5 2.0 9.9 0.0 1.4 3.1 0.8 0.1 1.4 0.9 1.0
Waist circumference 0.3 0.9 7.0 -0.2 -0.0 2.6 -0.0 -0.3 -0.1 0.2 0.6
Number of incorrect matches in round 1.0 1.7 3.7 -1.5 -1.2 0.4 -1.4 -0.3 -1.3 -1.6 -1.9
Past tobacco smoking 0.2 0.4 2.0 -0.1 -0.1 1.4 0.1 -0.4 -0.2 -0.9 -0.0
Alcohol usually taken with meals 0.3 0.5 2.3 -0.9 -0.4 -0.1 -0.6 -0.4 -0.2 -0.6 -1.5
Nervous feelings 0.6 1.1 3.2 -1.4 -0.4 -0.5 -1.7 0.5 -0.1 -0.1 -1.8
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.1 -1.0 -0.2 -1.0 0.1 0.2 -0.2 -0.1 -0.5
Hearing difficulty/problems with background noise 0.3 0.5 1.5 0.4 1.2 -0.1 1.0 -0.6 0.7 -0.4 0.2
Hair/balding pattern: Pattern 2 0.2 0.2 0.6 0.6 0.7 0.1 0.8 -0.0 0.3 0.0 0.3
Had menopause 0.5 0.7 1.2 0.2 -1.0 -0.4 -1.1 0.6 -0.8 0.9 -1.1
Had other major operations 0.3 0.3 1.4 0.4 0.5 1.2 0.7 -0.1 0.4 0.5 -0.3
Forced vital capacity (FVC) 0.1 0.2 1.0 -0.1 0.3 -0.5 -0.2 1.0 -0.1 0.0 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 1.8 -1.0 -1.2 0.5 -1.1 -0.6 -1.3 0.1 -0.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.7 -1.3 -0.1 -0.4 -0.2 -0.4 -0.1 -0.1 0.3
Qualifications: None of the above 0.8 1.7 6.2 0.2 -0.6 -2.3 -0.6 0.5 -0.7 -0.4 -2.5
Financial difficulties in last 2 years 0.6 0.7 3.3 -0.7 -0.8 1.8 -0.2 -0.8 -0.8 -0.5 0.0
Mouth/teeth dental problems 0.4 0.6 2.5 -1.6 -0.3 0.8 -0.4 0.4 -0.1 0.0 -1.3
Heart attack 0.6 0.7 2.0 -0.0 1.3 -0.4 -0.0 0.2 1.4 1.4 0.3
Allergy 0.3 0.8 2.6 1.6 -0.2 -0.7 0.8 0.6 -0.0 -0.2 1.4
Pain all over the body in last month 0.3 0.3 1.6 0.3 -0.5 0.2 -0.1 0.0 -0.5 1.3 0.5
Diabetes (self-reported) 0.3 0.5 2.2 0.3 0.2 0.0 1.2 0.2 0.2 0.7 1.5
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 2.8 -0.7 0.7 1.7 0.7 -0.4 0.5 0.2 0.1
Medication: Ramipril 0.0 0.0 0.1 0.2 -0.1 -0.2 -0.1 0.2 0.2 -0.2 -0.1
Medication: Simvastatin 0.2 0.3 0.7 0.6 0.6 -0.5 -0.3 0.0 0.8 0.7 0.6
Fluid intelligence score 1.8 3.7 7.4 1.7 1.9 0.7 2.7 2.2 1.1 2.7 1.2
Illnesses of siblings 0.7 0.9 3.0 0.5 0.1 1.0 1.2 1.7 -0.0 1.2 0.5
Neuroticism score 0.2 0.5 1.2 -1.1 -0.5 -0.2 -0.7 0.8 -0.2 -0.1 -1.1
Weight 0.4 2.0 11.0 0.1 1.3 3.3 1.1 -0.7 0.7 -0.3 1.1
Impedance of arm (right) 0.1 0.6 1.6 -0.7 1.0 0.1 -0.2 0.7 1.3 1.2 -0.2
Arm fat percentage (right) 0.4 1.4 8.8 -0.3 0.5 3.0 -0.0 -0.9 0.6 0.3 0.9
Trunk fat-free mass 0.3 1.8 4.9 0.3 1.3 2.2 1.6 -1.1 0.1 -1.8 0.9
Hip circumference 0.5 2.2 8.4 0.3 1.4 2.9 1.3 -0.8 1.2 0.0 1.8
Time employed in main current job 1.3 1.5 3.7 -0.9 -1.8 -0.4 -1.9 0.7 -1.4 0.7 -1.2
Alcohol intake versus 10 years previously 0.6 0.9 2.3 -0.4 -1.5 -0.5 -1.2 -0.3 -1.2 0.1 -1.1
Father’s age at death 1.4 1.9 3.6 -1.6 -1.2 0.7 -1.5 -1.9 -1.3 -1.6 -0.4
Worrier / anxious feelings 1.1 2.1 6.6 -1.4 -1.1 -0.9 -1.1 1.8 -0.9 -0.8 -2.6
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.7 0.6 0.4 -0.9 0.5 0.3 0.3 0.7 0.0
Falls in the last year 0.3 0.4 1.2 1.1 -0.5 -0.7 -0.2 0.7 -0.1 -0.5 -0.5
Hair/balding pattern: Pattern 3 2.2 3.2 6.2 -2.4 -2.5 0.3 -2.1 -0.3 -2.0 -0.7 -2.2
Number of live births 1.6 2.3 3.7 -0.5 -1.2 -1.5 -1.9 -1.9 -1.7 -1.9 -1.0
Forced expiratory volume in 1-second (FEV1) 0.8 2.7 4.9 -1.7 -1.9 -0.6 -2.0 0.6 -2.2 -0.6 -2.2
Pulse rate 1.4 2.4 10.7 0.2 1.4 3.3 1.5 -1.3 0.8 0.2 1.4
Happiness 1.0 1.2 3.1 1.6 0.6 -0.5 0.2 1.8 0.5 1.4 0.6
Noisy workplace 2.3 2.8 7.9 -1.4 -1.2 -2.4 -1.5 -1.0 -0.7 -2.8 -1.2
Qualifications: A levels/AS levels or equivalent 1.2 2.6 6.5 1.4 1.4 0.7 2.3 0.7 1.4 1.6 2.5
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.1 0.1 0.2 -0.5 -0.1 0.0 0.7 -1.1 -0.7
Mouth/teeth dental problems: Dentures 0.5 0.8 1.5 0.7 0.6 0.5 1.2 1.1 1.0 0.6 1.2
Asthma 0.4 0.8 3.2 -0.4 0.5 -0.8 -1.2 -1.8 0.4 -0.1 -0.5
Medication: Ibuprofen (e.g. Nurofen) 1.8 2.3 4.1 1.9 1.3 0.9 1.0 1.4 1.7 2.0 1.6
Medication: Cholesterol lowering 0.4 0.6 2.4 -0.3 0.4 -1.1 -0.4 -1.0 1.5 -0.1 0.1
Depression (self-reported) 0.4 0.4 1.6 0.4 0.7 0.0 0.5 1.2 0.8 0.3 -0.5
Medication: Lansoprazole 0.3 0.4 1.7 -1.3 -0.3 0.2 -0.7 0.1 0.1 -0.5 -0.7
Prospective memory result 1.3 1.6 3.7 -1.9 -1.3 1.2 -1.8 -0.3 -1.0 -0.1 -1.2
Lung cancer (father) 0.3 0.3 0.9 -0.5 0.6 -0.5 -0.0 0.6 0.6 0.9 -0.5
Illnesses of mother 3.2 3.9 10.3 1.5 1.5 2.1 2.2 1.9 1.2 3.2 1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 5.9 -1.9 -1.5 -0.2 -2.2 0.1 -1.6 -1.2 -2.4
Pulse wave Arterial Stiffness index 0.5 0.6 1.6 -0.6 -1.0 0.6 -1.3 -0.6 -0.9 -0.6 -0.4
Impedance of arm (left) 0.3 1.4 3.6 -0.3 1.4 0.7 0.2 1.1 1.8 1.9 0.4
Arm fat mass (right) 0.5 1.9 11.7 -0.2 0.7 3.4 0.5 -0.9 0.6 0.1 1.0
Trunk predicted mass 0.3 1.7 4.9 0.3 1.2 2.2 1.6 -1.1 0.0 -1.7 0.9
Standing height 0.3 2.6 8.8 0.4 3.0 1.9 2.3 0.4 1.6 -0.2 0.6
Length of working week for main job 0.1 0.1 0.2 0.3 -0.4 0.3 0.0 0.5 -0.1 0.2 0.2
Exposure to tobacco smoke at home 0.2 0.2 0.7 -0.0 0.2 0.4 0.5 -0.7 0.3 -0.8 0.0
Breastfed as a baby 0.9 1.1 4.5 -0.6 0.5 -2.1 1.1 0.2 0.2 -0.7 -1.3
Tense / ‘highly strung’ 0.6 1.0 2.6 -1.6 -0.7 -1.3 -1.0 -0.5 -0.0 -0.7 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.2 0.7 1.5 -0.9 0.6 1.0 0.9 0.5 -0.5
Hair/balding pattern: Pattern 4 0.1 0.3 1.0 -0.8 -0.4 -0.3 -0.9 -1.0 0.0 0.0 0.2
Birth weight of first child 0.6 1.2 2.1 1.3 1.1 -1.2 0.8 1.4 1.4 -0.2 -0.3
Peak expiratory flow (PEF) 1.6 3.6 6.2 -2.4 -2.5 -0.7 -2.1 0.7 -2.4 0.8 -2.3
Pulse wave reflection index 1.5 1.8 4.3 -1.3 -1.6 -1.0 -1.5 -0.2 -1.4 -0.6 -2.1
Ever highly irritable/argumentative for 2 days 0.7 0.9 3.7 -1.9 -0.7 -0.5 -0.1 1.1 -0.1 -0.3 -1.1
Loud music exposure frequency 1.6 1.8 5.4 -1.1 -1.2 -0.6 -1.1 -1.9 -0.7 -2.3 -0.7
Qualifications: O levels/GCSEs or equivalent 3.2 5.1 11.6 2.4 2.5 0.9 3.3 0.2 2.0 1.1 3.4
Mouth/teeth dental problems: Bleeding gums 0.8 1.1 4.8 1.1 0.2 0.1 -0.9 -2.2 -0.4 -0.7 1.0
Blood clot in the leg (DVT) 0.4 0.6 1.4 1.2 0.9 -0.3 0.2 0.8 0.4 0.9 0.7
Medication: Paracetamol 1.5 2.4 4.9 -1.8 -1.6 -1.9 -1.3 0.3 -1.4 -1.3 -2.2
Headache pain in last month 2.3 3.9 8.5 -1.8 -2.6 -0.4 -2.0 -0.5 -2.4 -1.6 -2.9
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.2 0.6 0.4 0.0 0.9 0.9 -0.7 1.1 -0.1
Glaucoma (self-reported) 3.4 4.0 8.8 2.3 2.4 1.0 3.0 1.2 2.1 1.7 1.8
Gout (self-reported) 0.7 0.9 1.8 -1.2 -1.2 0.0 -0.6 -1.1 -1.0 -0.3 -1.4
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 9.0 -0.3 0.2 -2.3 -1.3 -3.0 -0.6 -2.7 -0.5
Medication: Amlodipine 0.4 0.5 1.1 0.6 0.9 -0.8 0.3 -0.2 1.0 0.3 1.0
Medication: Ventolin 100micrograms inhaler 1.3 1.7 3.1 -1.2 -1.4 -0.6 -1.5 -1.8 -1.5 -0.8 -1.2
Birth weight 0.2 0.5 1.7 -0.3 -1.2 0.6 0.2 0.5 -1.3 0.0 0.3
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.1 -1.4 -0.5 -0.8 -1.3 -0.7 -0.4 -1.3 -1.1
High blood pressure (siblings) 1.0 1.5 5.8 0.4 0.2 -1.4 -1.5 -1.3 0.1 -2.4 -0.1
Forced vital capacity (FVC), Best measure 0.2 0.7 2.7 -0.9 0.2 -0.2 -0.7 0.5 -0.1 -1.2 -1.6
Body fat percentage 0.3 1.1 6.4 -0.3 0.5 2.5 -0.0 0.2 0.9 1.2 0.4
Leg fat percentage (right) 0.4 1.3 4.2 -1.1 -1.4 2.1 -1.4 0.0 -0.8 0.3 -0.8
Arm fat-free mass (right) 0.3 1.3 4.0 0.7 1.1 2.0 1.7 -0.4 0.1 -0.6 1.2
Exposure to tobacco smoke outside home 0.4 0.6 3.9 0.1 0.2 -0.3 -0.0 -0.6 0.5 -2.0 0.4
Comparative body size at age 10 0.4 1.0 4.5 1.3 0.4 0.1 0.9 -0.3 0.4 0.5 2.1
Number of full brothers 1.0 1.2 3.8 1.9 1.3 0.2 1.4 0.8 0.9 -0.6 0.9
Worry too long after embarrassment 0.4 0.7 1.5 -1.0 0.7 0.9 0.8 0.4 1.0 1.2 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.9 0.7 1.4 -1.6 0.8 1.7 1.3 -0.4 -0.2
Wheeze or whistling in the chest in last year 0.3 0.5 3.3 -0.4 0.1 -1.8 -0.6 -0.6 0.1 -0.3 -0.4
Number of children fathered 3.3 3.7 5.0 2.2 1.9 1.3 2.2 1.7 1.6 2.2 2.0
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.7 0.3 0.2 0.3 0.7 -0.4 -0.2 -0.7 0.8
Age at first live birth 0.2 0.4 1.2 0.8 0.8 -0.4 -0.1 0.6 0.3 0.5 1.1
Pulse wave peak to peak time 0.6 0.7 1.6 0.5 1.1 -0.4 1.3 0.7 1.0 0.9 0.5
Health satisfaction 1.1 1.4 3.0 1.6 1.5 -0.4 0.3 -1.3 1.7 -0.1 1.2
Shortness of breath walking on level ground 0.5 0.5 1.5 0.4 0.8 0.7 1.0 0.4 1.2 0.5 0.5
Qualifications: College or University degree 1.0 3.1 7.1 1.4 2.7 0.8 1.8 0.3 2.1 1.6 2.2
Eye problems/disorders: None of the above 0.3 0.4 1.7 -0.5 -0.2 -0.8 -0.5 -0.2 -0.2 -0.5 -1.3
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.3 0.9 -0.7 -1.5 -0.2 -0.0 -0.0 -0.6 1.1
Emphysema/chronic bronchitis 0.1 0.1 0.7 -0.0 -0.2 0.4 -0.3 0.1 0.8 0.4 0.2
Medication for pain relief, constipation, heartburn 0.4 0.6 1.8 0.6 0.6 1.0 1.4 0.1 -0.5 0.6 1.0
Neck or shoulder pain in last month 1.4 2.0 10.5 -0.5 -1.1 -3.2 -0.4 0.9 -0.5 -0.5 -1.5
Medication: Blood pressure 0.3 0.6 1.6 -1.2 -1.0 0.7 -0.6 -0.6 -0.2 -0.7 -0.7
Angina (self-reported) 0.1 0.2 0.6 -0.6 0.1 -0.2 -0.3 0.0 0.2 -0.7 -0.7
Migraine (self-reported) 0.5 0.6 2.4 0.1 -0.9 -0.2 -0.7 0.1 -0.6 -1.5 -0.8
Medication: Ibuprofen 1.4 1.7 4.2 2.1 1.3 -0.3 0.8 1.0 1.6 1.1 1.4
Medication: Allopurinol 0.2 0.3 1.3 -0.7 -0.2 -0.3 0.0 -0.6 -0.0 1.2 -0.4
Medication: Omeprazole 0.9 1.0 3.4 -0.7 -0.3 0.3 -0.8 -1.5 0.1 -1.9 -1.2
Medication: Seretide 50 evohaler 1.0 1.1 2.7 0.9 1.7 -0.1 1.1 0.2 1.6 1.1 0.8
Mean time to correctly identify matches 1.3 2.5 6.1 -1.0 -1.4 -0.9 -2.5 -0.8 -1.1 -2.0 -2.0
Heart disease (mother) 1.1 1.3 2.2 -0.4 -1.1 -1.2 -1.3 -0.8 -1.3 -1.5 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 3.8 -0.6 -0.6 -0.3 -0.6 -0.4 -0.3 1.9 0.2
Whole body fat mass 0.4 1.6 9.3 -0.2 1.0 3.0 0.5 -0.2 1.0 0.6 0.7
Leg fat mass (right) 0.2 0.9 6.8 -0.7 -0.3 2.6 -0.3 -0.2 0.0 0.2 0.0
Arm predicted mass (right) 0.3 1.5 4.0 0.6 1.2 2.0 1.9 -0.6 0.4 -0.8 1.3
Pulse rate, automated reading 0.2 0.7 1.8 0.5 1.0 1.1 0.6 0.6 1.4 -0.2 0.8
Alcohol intake frequency. 0.6 1.4 3.8 -1.1 -2.0 -0.4 -0.4 -1.1 -1.4 -1.0 -1.4
Comparative height size at age 10 0.3 1.7 4.4 -0.8 2.1 2.1 1.6 0.1 1.0 -0.7 -0.5
Number of full sisters 1.0 1.3 2.7 1.4 1.6 -0.1 1.0 -1.2 0.6 0.3 1.7
Suffer from ‘nerves’ 0.3 0.4 1.0 -0.4 0.1 0.6 -0.0 1.0 0.7 1.0 -0.6
Overall health rating 0.1 0.2 0.7 -0.2 -0.2 -0.2 0.1 -0.8 0.4 -0.8 -0.1
Chest pain or discomfort 0.1 0.2 0.8 -0.6 0.4 -0.2 0.9 0.1 0.5 0.1 0.2
Had major operations 0.6 0.7 1.6 -0.9 -0.5 1.3 -0.8 -0.8 -0.2 -0.7 -0.9
Age at last live birth 0.5 0.7 3.3 1.2 0.6 -0.1 -0.2 -0.3 0.2 0.2 1.8
Family relationship satisfaction 0.7 0.8 3.3 1.5 0.7 -0.3 -0.2 0.3 0.4 0.4 1.8
Leg pain on walking 1.9 2.4 4.9 -2.2 -1.6 -0.4 -1.8 -1.3 -1.4 -1.0 -2.0
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.9 -0.8 -0.2 1.7 0.6 -0.1 0.4 -0.4 0.8
Commuting to job workplace: Car/motor vehicle 0.7 0.8 1.9 1.1 0.5 1.4 0.7 -1.1 -0.5 0.2 1.3
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.1 0.9 0.7 -0.4 0.5 0.2 -0.0 1.0 1.0
Medication: Aspirin 0.4 0.5 1.3 0.1 0.3 -0.1 -0.7 1.0 1.1 1.1 0.2
Supplements: Vitamin C 0.2 0.3 1.1 -0.3 -0.2 -0.6 -1.0 0.1 0.1 -0.2 -0.6
Knee pain experienced in last month 0.7 1.1 3.0 0.1 -1.2 1.1 -1.7 0.1 -1.4 -0.7 -0.8
Hypertension (Self-reported) 0.5 1.3 2.5 -1.5 -1.3 1.0 -0.8 -1.5 -0.7 -1.6 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.4 1.7 5.8 -0.3 0.2 -2.2 -1.2 -0.8 0.4 -2.4 -0.9
Illnesses of father: Heart disease 1.3 1.8 7.6 -1.1 -0.7 -2.8 -1.6 -0.7 -0.2 -0.7 -1.4
Illnesses of siblings: Diabetes 0.3 0.4 0.8 -0.4 -0.9 0.8 -0.8 0.6 -0.6 0.7 -0.3
Smoking status: Previous 0.7 1.0 2.2 -0.7 -1.2 -1.5 -1.3 0.2 -0.9 0.0 -1.3
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.8 0.0 1.3 0.0 0.9 0.3 1.2 0.9 0.5
Whole body fat-free mass 0.4 2.3 5.6 0.6 1.6 2.4 1.9 -1.2 0.5 -1.4 1.5
Leg fat-free mass (right) 0.6 3.0 5.4 1.1 2.2 2.3 2.1 -1.0 1.3 -1.0 2.2
Arm fat percentage (left) 0.4 1.7 9.8 -0.2 0.7 3.1 0.2 -0.6 1.0 0.5 1.1
Average weekly red wine intake 1.2 1.8 4.9 -1.8 -0.6 0.9 -1.0 -2.2 -0.7 -1.4 -1.4
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.1 -0.1 -0.1 -0.6 -0.6 1.1 0.4 0.4 0.1
Mood swings 0.2 0.3 1.2 -0.7 -0.6 0.6 0.1 0.1 -1.1 0.4 0.2
Loneliness, isolation 0.5 0.7 2.5 -0.2 0.1 -1.4 -0.7 0.6 0.5 1.6 0.6
Long-standing illness, disability or infirmity 0.5 0.8 2.5 -1.3 -0.3 0.2 -0.2 -1.6 0.1 -1.2 -0.6
Ever had bowel cancer screening 0.8 1.0 2.5 -0.2 0.5 -1.6 0.3 1.5 0.8 1.1 -0.9
Diabetes diagnosed by doctor 0.3 0.4 1.6 0.1 0.2 -0.1 1.3 0.3 0.2 0.6 1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.6 2.7 0.8 0.4 0.8 -0.4 -0.0 0.3 0.2 1.6
Friendships satisfaction 0.5 0.6 1.2 0.8 0.9 -0.6 0.2 -1.1 0.7 0.6 1.1
Qualifications: nursing, teaching 0.9 1.5 3.5 1.7 1.1 1.4 0.5 -1.4 -0.2 0.2 1.9
Commuting to job workplace: Walk 1.6 1.7 10.6 -0.5 -0.4 -3.2 -0.6 0.1 0.5 -1.3 -0.6
Eye problems/disorders: Cataract 1.8 2.1 6.6 1.5 1.5 0.7 1.2 0.8 1.5 0.9 2.6
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 2.0 0.2 -1.0 -1.4 -1.0 -0.8 -0.9 -0.5 0.0
Medication for cholesterol 0.7 1.1 4.7 0.2 0.7 1.0 0.6 2.2 1.2 0.8 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.8 7.5 0.7 0.7 -2.7 -0.1 1.0 1.3 -1.8 -0.2
Back pain experienced in last month 0.1 0.2 0.5 0.7 0.4 -0.1 0.0 0.3 0.2 -0.4 -0.7
Mineral and other dietary supplements 3.9 5.3 12.5 2.3 2.2 0.9 2.3 1.7 2.3 2.3 3.5
Breast cancer (self-reported) 1.1 1.3 3.1 -0.3 1.5 0.6 1.8 -1.5 1.2 -0.8 0.5
Asthma (self-reported) 0.5 0.9 4.0 -0.7 0.4 -0.7 -1.3 -2.0 0.3 -0.2 -0.7
Osteoporosis (self-reported) 0.3 0.3 0.9 0.7 0.3 -0.5 -0.8 0.2 0.7 0.9 0.1
Osteoarthritis (self-reported) 1.9 2.4 4.9 -1.7 -2.2 0.2 -2.0 -0.0 -1.7 -0.9 -1.9
Medication: Aspirin 0.4 0.5 1.8 0.1 0.4 -0.2 -0.6 0.9 1.1 1.4 -0.1
Medication: Gliclazide 0.2 0.2 0.6 -0.0 -0.8 -0.6 0.4 0.7 -0.5 -0.2 0.2
Illnesses of father: None of the above (group 1) 1.1 1.3 5.3 1.3 0.9 2.3 0.5 0.9 0.8 0.8 0.6
Smoking status: Current 1.7 2.8 7.1 2.1 2.1 -0.1 1.8 0.4 1.5 0.9 2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 4.4 -1.5 -1.6 -0.9 -2.1 0.2 -2.1 -0.4 -2.0
Whole body water mass 0.4 2.5 6.1 0.6 1.7 2.5 1.9 -1.3 0.6 -1.5 1.6
Leg predicted mass (right) 0.6 3.2 5.4 1.1 2.3 2.3 2.1 -1.0 1.3 -1.0 2.3
Arm fat mass (left) 0.4 1.8 12.1 -0.4 0.6 3.5 0.2 -0.9 0.6 -0.0 0.8
Number of self-reported non-cancer illnesses 0.6 1.1 2.8 -0.7 0.7 -1.0 -1.0 -1.3 0.9 -1.7 -0.6
Average weekly champagne plus white wine intake 0.6 0.9 1.8 1.3 1.0 -0.6 1.2 -0.9 0.6 -0.6 0.9
Miserableness 0.2 0.3 1.0 0.3 -0.3 -1.0 -0.3 -0.2 -0.5 -0.5 -0.9
Guilty feelings 0.8 1.2 2.2 0.5 1.1 -1.2 0.9 1.2 1.3 1.5 0.7
Wears glasses or contact lenses 2.3 2.6 6.4 -2.5 -1.8 2.2 -1.4 -0.9 -0.9 -0.8 -1.4
Ever taken oral contraceptive pill 2.2 2.5 4.3 1.4 2.1 1.4 1.6 -1.3 1.3 1.8 1.6
Hearing aid user 2.9 3.3 5.9 -1.8 -1.4 -0.6 -1.9 -2.1 -1.9 -2.4 -1.7
Mother’s age at death 0.3 0.4 2.1 -0.2 -0.1 0.8 -0.1 0.9 -0.0 1.4 -0.1
Financial situation satisfaction 1.1 1.3 2.2 -1.1 -1.3 -1.5 -1.1 -1.5 -0.8 -1.3 0.0
Tinnitus: Yes, now most or all of the time 2.9 3.4 6.9 -2.4 -2.3 0.1 -2.6 -0.3 -2.2 -0.5 -2.0
Commuting to job workplace: Public transport 0.4 0.4 1.7 -0.6 0.3 -0.6 0.6 1.3 0.7 0.3 -0.1
Eye problems/disorders: Glaucoma 3.3 3.9 8.7 2.6 2.3 0.3 2.9 1.2 2.2 1.7 1.1
Medication: Blood pressure 0.4 0.8 4.0 -0.3 -0.1 -0.1 0.5 -2.0 -0.4 -1.2 0.3
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.9 0.6 -0.1 -1.4 -1.3 -0.3 -0.7 -0.9 -1.4
Supplements: Fish oil (including cod liver oil) 1.9 2.4 5.5 -1.8 -1.6 -0.3 -1.7 -0.7 -1.6 -1.3 -2.3
High cholesterol (Self-reported) 0.3 0.6 2.7 -0.1 1.1 0.6 -0.6 -0.2 1.6 0.2 0.5
Medication: Bendroflumethiazide 0.7 1.0 3.2 -1.2 -1.0 0.7 -0.0 -1.8 -1.2 -0.3 -0.6
Medication: Paracetamol 1.5 2.3 4.7 -1.7 -1.3 -2.1 -1.2 0.0 -1.0 -1.6 -2.2
Medication: Lisinopril 0.2 0.3 0.8 -0.9 -0.5 0.8 -0.8 0.2 -0.2 0.2 0.1
Medication: Atorvastatin 0.2 0.2 0.5 -0.2 0.4 -0.2 -0.3 -0.6 0.7 -0.2 0.5
Illnesses of father: High blood pressure 1.1 1.3 2.9 -1.7 -1.1 0.3 -0.9 -1.3 -1.1 -1.6 -0.2
Alcohol drinker status: Never 0.7 0.8 3.6 0.4 0.6 -1.0 -0.2 -0.9 0.4 -1.9 0.6
Ever smoked 0.7 1.2 3.0 1.1 1.2 0.1 0.9 0.3 1.1 1.7 1.4
Basal metabolic rate 0.4 2.4 7.5 0.6 1.7 2.7 1.8 -1.1 0.7 -1.1 1.5
Leg fat percentage (left) 0.3 1.2 3.3 -0.8 -1.4 1.8 -1.3 0.5 -0.8 0.6 -0.8
Arm fat-free mass (left) 0.3 1.4 4.8 0.2 1.0 2.2 1.6 -1.0 -0.0 -1.0 0.8
Number of operations (self-reported) 0.2 0.4 2.0 -0.0 0.1 1.4 0.1 0.3 0.6 -0.0 -0.6
Average weekly beer plus cider intake 0.6 0.9 3.9 0.3 -0.4 0.1 -0.0 2.0 -0.3 1.6 0.7
Irritability 0.4 0.7 3.3 -1.8 -0.8 0.6 -0.1 0.1 -0.6 -0.5 -0.7
Risk taking 0.6 0.9 3.0 -0.1 0.3 1.7 0.3 -1.3 0.3 -0.7 1.2
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.9 -0.1 0.6 -0.2 -1.2 -0.1 0.7 -1.7 -0.6
Fractured/broken bones in last 5 years 0.9 1.2 4.8 0.9 0.1 -0.8 0.4 -1.8 -0.0 -2.2 0.2
Age started oral contraceptive pill 1.1 1.4 3.8 0.1 0.9 -0.9 1.4 1.6 0.8 2.0 -0.2
Diastolic blood pressure, automated reading 0.5 1.5 3.4 -1.2 -1.2 0.5 -0.8 -1.6 -1.1 -1.8 -0.9
Ever depressed for a whole week 0.3 0.3 1.7 -1.3 -0.6 0.3 -0.1 0.0 -0.4 0.6 -0.4
Unable to work because of sickness or disability 0.9 1.1 2.6 0.9 1.4 0.3 1.6 0.8 1.3 0.7 0.8
Commuting to job workplace: Cycle 1.0 1.2 5.6 0.7 1.1 -2.4 -0.1 -0.7 0.9 -0.8 0.8
Myopia 0.4 0.6 2.0 0.6 0.2 -1.4 -0.9 -1.0 0.2 -0.5 0.0
Vascular/heart problems diagnosed by doctor 0.8 2.2 3.9 2.0 1.8 -1.7 1.3 1.4 1.4 1.5 0.5
Cholesterol lowering medication 0.2 0.3 0.8 0.9 0.6 -0.9 0.4 0.4 0.1 0.3 0.6
Medication: Omeprazole (e.g. Zanprol) 1.3 1.5 4.6 -1.0 -0.2 -0.0 -1.2 -1.9 0.1 -2.1 -1.3
Pain experienced in last month 0.6 1.0 2.3 0.0 0.6 0.8 1.4 0.6 0.9 1.3 1.5
Supplements: Calcium 1.0 1.1 3.0 0.5 -0.1 -1.6 -1.0 -1.7 -0.4 -1.1 -1.0
Basal cell carcinoma (self-reported) 0.4 0.4 0.7 -0.7 -0.8 0.5 -0.8 -0.5 -0.8 -0.4 -0.6
Heart attack/myocardial infarction (self-reported) 0.7 0.9 2.7 -0.0 1.5 -0.3 0.3 0.2 1.5 1.6 0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 1.3 1.2 0.9 0.1 0.2 0.7 0.4 1.0 0.7
Heart disease (siblings) 0.7 0.8 1.5 -0.9 -0.7 -0.2 -0.1 -1.1 -1.2 -1.2 -1.1
Alcohol drinker status: Previous 0.3 0.4 1.8 0.2 0.2 1.4 0.8 -0.5 0.1 0.4 0.2
Pack years of smoking 0.3 0.4 2.6 -0.6 0.2 -1.6 0.4 -0.3 0.0 -0.2 -0.3
Impedance of whole body 0.3 1.7 6.7 -0.3 0.5 -0.9 -0.2 2.1 0.8 2.6 -0.9
Leg fat mass (left) 0.2 0.8 5.9 -0.5 -0.1 2.4 -0.1 0.0 0.2 0.3 0.1
Arm predicted mass (left) 0.2 1.2 3.9 0.4 0.9 2.0 1.5 -0.8 -0.0 -1.0 1.0