Hub : Genes

AEBP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3750	0.0580	7.8e-16	0.097	0.139	0.150	0.147	0.159	7.3e-12	1.3e-16	7.5e-18	1.6e-17	6.8e-19
2	GTEx	Artery Aorta	0.3690	0.0680	2.5e-10	0.208	NA	0.190	NA	0.231	1.2e-11	NA	9.9e-11	NA	6.0e-13
3	GTEx	Artery Tibial	0.3268	0.0627	5.4e-10	0.125	NA	0.140	NA	0.149	5.3e-10	NA	4.0e-11	NA	9.7e-12
4	GTEx	Ovary	0.2360	0.1050	7.2e-03	0.117	NA	-0.002	NA	0.072	8.6e-04	NA	3.7e-01	NA	7.8e-03
5	ROSMAP	Brain Pre-frontal Cortex	0.3408	0.0518	0.0e+00	0.199	0.173	0.190	0.203	0.213	4.5e-25	9.8e-22	6.5e-24	1.8e-25	7.8e-27
6	YFS	Blood	0.0484	0.0153	6.2e-09	0.013	0.022	0.027	0.022	0.020	2.2e-05	6.0e-08	3.1e-09	7.3e-08	3.5e-07
7	TCGA	Breast Invasive Carcinoma	0.0228	0.0116	8.6e-04	0.009	0.010	0.011	NA	0.013	4.5e-03	2.8e-03	1.6e-03	NA	9.1e-04
8	TCGA	Liver Hepatocellular Carcinoma	0.1570	0.0790	7.1e-03	0.080	0.040	0.060	NA	0.080	1.4e-04	5.7e-03	8.6e-04	NA	1.3e-04
9	TCGA	Lung Adenocarcinoma	0.0763	0.0342	1.1e-04	0.032	0.035	0.041	NA	0.044	1.2e-04	5.9e-05	1.5e-05	NA	6.7e-06
10	TCGA	Lung Squamous Cell Carcinoma	0.1082	0.0486	2.9e-05	0.061	0.038	0.028	NA	0.047	1.9e-07	3.6e-05	3.6e-04	NA	4.1e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.9	1.4	3.4	-1.6	-1.4	-1.1	-0.7	-0.9	-0.4	-1.3	0.2	-1.9	-1.3
Bipolar Disorder or Schizophrenia	1.0	2.5	5.6	-2.4	-1.4	-1.3	0.1	-1.9	-1.9	-1.4	0.5	-2.0	-1.4
Depressed Affect (Nagel 2018)	0.6	1.3	5.9	-0.0	1.1	1.0	2.4	0.0	-1.1	0.7	-1.1	0.5	1.4
Depression (Nagel 2018)	1.4	2.0	9.3	0.3	1.1	1.2	3.0	0.2	-1.1	0.2	-2.0	0.9	1.6
Intelligence (Savage-Jansen 2018)	0.9	2.7	9.7	-0.3	-1.5	-1.1	2.3	0.4	3.1	-1.9	-0.7	-1.6	-1.3
Neuroticism (Nagel 2018)	0.7	1.6	3.5	0.9	1.2	1.2	1.9	1.0	-1.2	0.9	-1.6	1.3	1.2
Schizophrenia (2018)	0.7	1.5	4.6	-1.8	-0.8	-0.7	0.6	-1.7	-2.1	-0.7	0.6	-1.1	-0.7
Schizophrenia vs Biploar Disorder	0.4	0.5	1.4	0.5	0.9	0.2	0.1	0.2	-1.2	0.6	-0.2	1.0	1.0
Worry (Nagel 2018)	0.5	1.0	3.9	0.8	0.8	1.1	2.0	0.6	-1.4	0.2	-0.4	0.9	0.1
Alzheimer’s Disease (in mother)	0.6	0.7	2.6	0.6	-0.0	-1.0	-1.4	0.3	-0.5	0.7	1.6	0.2	0.5
Alzheimer’s Disease (in father)	0.8	0.9	2.6	-0.7	1.2	0.8	-0.9	-0.9	-0.5	1.6	-0.2	0.7	1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	3.0	-0.1	0.8	-0.2	-1.7	-0.1	-0.6	1.6	1.5	0.6	1.1
Crohns Disease (2017)	0.9	2.0	7.1	0.4	0.3	0.1	-0.9	1.8	2.7	1.0	-2.6	0.3	0.7
Irritable Bowel Disease (IBD)	1.2	2.9	10.2	1.0	-0.1	-0.6	-2.0	2.0	2.9	0.7	-3.2	0.3	0.6
Ulcerative Colitis (UC)	1.0	1.8	6.6	1.0	-0.4	-1.0	-2.2	1.3	1.6	0.3	-2.6	0.1	0.3
Major Depression (MDD)	0.8	0.9	3.7	-0.2	0.5	1.3	1.2	-0.4	-1.2	0.1	1.9	0.7	0.0
Reaction Time	1.1	2.2	4.9	0.1	-1.9	-1.6	0.8	-0.6	0.5	-2.0	-2.2	-1.3	-2.0
Verbal and Numeric Reasoning (VNR)	0.4	0.9	4.0	0.5	0.5	0.5	1.6	1.0	2.0	0.1	-0.4	0.2	0.3
Breast Cancer	0.4	1.0	2.9	0.5	1.2	0.8	-0.1	0.3	-0.4	1.3	-1.4	1.7	1.0
Ovarian Cancer	0.2	0.3	0.8	-0.4	-0.2	-0.0	-0.5	-0.3	-0.9	-0.6	0.8	-0.1	0.2
Prostate Cancer	0.4	0.6	3.6	-1.0	0.2	0.2	0.3	-1.0	-1.9	0.1	-0.5	0.2	0.1
Age at First Birth	1.1	1.6	3.9	1.1	1.3	1.2	0.2	0.5	0.5	2.0	1.6	1.8	1.0
Bipolar Disorder (2011)	0.6	0.6	3.0	0.0	0.0	-1.6	-1.7	-0.7	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.8	1.1	2.2	-0.1	1.5	1.5	0.5	-0.4	-0.4	1.4	-0.8	1.3	1.4
Coronary Artery Disease (CAD)	1.4	1.6	4.5	0.5	-1.5	-1.2	-1.3	1.1	2.1	-1.8	0.0	-0.8	-1.0
Crohns Disease (2012)	0.2	0.4	2.8	-1.0	0.1	-0.2	-0.1	0.1	1.7	0.0	0.0	-0.3	0.0
Mean Putamen Volume	0.8	0.9	3.0	-0.5	0.3	0.0	-0.0	-1.4	-1.7	0.7	1.6	0.4	0.7
Fasting Glucose	3.8	4.6	18.8	4.3	1.3	-0.1	-0.3	3.0	2.4	1.1	-0.5	2.0	2.2
HbA1C	1.1	1.3	3.7	0.3	1.0	0.1	-0.7	-0.0	1.8	1.6	1.9	-0.1	1.2
HDL Cholesterol	0.5	0.8	3.2	0.2	-1.2	-0.8	0.2	0.2	0.3	-0.7	0.8	-1.0	-1.8
LDL Cholesterol	1.4	2.2	15.3	-0.6	-0.7	-1.7	-1.3	-0.4	3.9	0.2	-0.7	-0.9	-0.0
Lupus	0.2	0.4	1.1	0.3	-0.5	-0.3	0.8	0.2	1.0	-0.7	0.3	-0.2	-0.8
Neuroticism (2016)	0.2	0.3	1.1	-0.5	-0.5	-0.6	0.8	0.4	0.5	-0.1	0.1	-1.0	-0.3
Primary Biliary Cirrhosis	0.6	0.8	3.7	1.9	0.6	0.5	0.7	1.3	-0.7	0.6	1.0	0.4	0.1
Rheumatoid Arthritis	0.5	0.7	3.7	1.0	-0.1	-0.5	-1.9	1.0	-0.9	0.0	0.0	0.3	0.3
Schizophrenia (2014)	1.0	2.3	7.3	-2.0	-1.1	-0.9	0.7	-1.9	-2.7	-1.4	-0.5	-1.5	-0.9
Triglycerides	2.0	3.3	16.0	1.6	0.6	-0.5	-0.3	1.6	2.8	0.8	-4.0	0.8	1.4
Type 2 Diabetes (T2D) (2012)	1.3	1.5	5.0	-0.8	-1.5	-1.9	0.6	-0.3	0.1	-1.3	-1.0	-2.2	-0.7
Ulcerative Colitis	1.2	1.8	3.9	1.4	-1.0	-1.4	-2.0	1.8	1.5	-0.6	-1.6	-0.2	-0.2
Blood Eosinophil Count	0.2	1.8	5.5	-0.3	-1.2	-1.1	-1.2	0.1	1.4	0.0	1.8	-1.7	-2.4
Blood Platelet Count	0.2	2.1	5.8	0.1	-1.7	-1.9	-0.2	0.5	0.1	-1.3	-2.4	-2.0	-1.8
Blood Red Count	0.3	2.6	10.9	-3.3	0.3	-0.0	-1.4	-2.8	-0.9	0.8	1.4	-1.4	-0.1
Blood White Count	0.2	1.3	4.1	0.6	-1.4	-1.9	-0.3	0.6	0.9	-0.2	-0.5	-1.4	-2.0
Heel T-Score	0.1	1.1	4.2	-0.6	0.7	0.7	0.9	-0.5	-2.0	0.8	1.6	1.0	0.2
BMI	0.3	1.5	3.8	-1.0	1.3	1.8	-0.0	-1.6	-1.2	0.9	1.9	0.7	0.4
Height	0.6	12.4	29.6	-5.1	-2.2	-1.3	3.3	-5.4	-2.3	-2.6	5.0	-3.3	-1.9
Waist Hip Ratio (WHR)	0.4	1.8	6.0	-1.0	0.4	0.4	1.9	-1.1	1.9	0.0	-2.4	0.2	1.4
Systolic Blood Pressure	0.9	4.7	14.5	3.7	-0.7	-1.8	-2.2	3.8	3.0	-0.4	-0.9	-0.1	-0.5
Smoking Status	0.4	0.9	5.5	-1.0	0.0	0.2	2.4	-0.6	-0.5	-0.1	1.1	-0.3	-0.4
Allergy or Eczema	1.0	2.6	11.4	-0.9	-1.8	-1.6	3.4	-1.4	0.0	-1.7	-1.4	-0.7	-0.6
Cardiovascular Disease	0.6	1.9	9.0	1.3	0.1	-0.9	-0.2	1.6	3.0	0.0	-1.9	-0.1	0.9
Hypothyroidism (self reported)	0.4	0.9	5.7	0.5	0.2	0.0	-0.5	0.4	2.4	1.0	1.3	0.2	-0.3
Respiratory disease	0.4	0.9	1.7	-0.9	1.1	0.9	-1.1	-1.0	0.8	1.3	0.9	0.6	0.8
Type 2 Diabetes (T2D) (2018)	0.7	1.3	5.9	-2.4	-0.3	-0.1	0.1	-2.3	-0.7	-0.7	-0.4	-1.0	-0.2
Lung FEV1/FVC ratio	0.7	3.5	7.9	2.8	1.5	1.6	0.1	2.8	1.3	1.5	-1.4	2.3	1.9
Lung FVC	0.6	2.9	7.8	0.2	-2.3	-2.1	2.8	0.4	0.3	-2.1	0.4	-1.3	-2.3
Neuroticism	0.4	1.1	4.3	0.5	1.0	0.9	1.5	0.4	-2.1	0.7	-0.5	0.7	0.8
Chronotype (morning person)	0.7	1.7	13.5	0.8	-0.1	0.0	-3.7	0.6	0.4	0.6	-1.2	0.6	-0.3
Hair Pigment	0.0	0.9	3.1	0.1	0.4	0.0	-1.4	0.6	1.6	1.8	-0.7	-0.1	-0.0
Tanning	0.1	1.1	4.8	0.3	0.4	0.4	-1.4	-0.3	-1.2	1.1	2.2	0.9	-0.0
Hand grip strength (left)	0.4	1.0	3.7	-0.6	0.7	1.1	1.9	-0.8	-0.8	0.4	1.3	0.9	0.3
Number of treatments/medications taken	1.2	2.2	13.5	-0.6	-1.0	-1.1	-0.5	0.4	3.7	-0.8	-1.1	-1.4	-1.4
Average weekly spirits intake	2.2	2.7	7.2	-1.4	-1.7	-2.0	2.7	-1.7	-1.3	-1.3	-0.8	-1.6	-1.3
Sensitivity / hurt feelings	0.1	0.1	0.5	0.1	-0.1	-0.2	-0.7	0.2	0.5	0.3	-0.2	0.2	-0.4
Frequency of depressed mood in last 2 weeks	2.6	3.6	8.1	0.7	2.6	2.8	2.2	0.3	-1.0	1.4	-0.8	2.4	2.6
Hearing difficulty/problems: Yes	1.4	2.1	8.1	0.1	1.8	2.1	2.8	0.2	-0.0	1.3	0.0	1.4	1.3
Relative age of first facial hair	0.8	1.6	4.6	1.7	1.5	1.3	0.5	1.0	-0.5	1.1	-0.2	2.1	1.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	7.3	-0.1	0.7	0.4	0.7	0.4	1.8	0.5	-2.7	1.0	1.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.9	-0.7	0.0	-0.0	-0.5	-0.9	-0.2	-0.4	0.3	0.3	0.7
Ever had hysterectomy (womb removed)	1.8	2.0	3.6	0.9	1.9	1.9	0.1	0.6	-0.5	1.6	-1.4	1.9	1.8
Systolic blood pressure, automated reading	0.9	2.5	6.5	1.4	-1.9	-2.6	-1.6	1.1	0.9	-2.2	-0.4	-1.3	-1.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.6	-1.2	-0.3	-0.1	0.7	-0.9	-0.2	-0.4	-1.1	-0.5	-0.5
Angina	0.8	1.0	3.3	-0.5	0.9	0.5	1.7	-0.6	0.9	0.7	-1.8	0.3	1.1
Medication for hormone replacement therapy	0.4	0.5	2.0	0.3	0.4	0.4	-1.3	0.7	0.0	0.5	1.4	0.3	0.2
Vitamin and mineral supplements	0.5	0.6	2.1	-0.2	1.1	1.4	-0.0	-0.5	-1.1	0.2	0.1	0.3	1.2
Supplements: Zinc	0.5	0.5	2.1	0.3	0.2	-0.3	-0.4	0.6	1.4	1.2	-0.5	0.4	0.5
Medication: Co-codamol	1.0	1.2	5.8	-2.4	-0.1	0.8	-0.6	-2.0	0.2	-0.0	-0.8	-0.5	0.0
Medication: Metformin	1.8	2.5	8.5	-2.9	-0.8	-0.7	-1.0	-2.8	-0.4	-1.0	-1.5	-1.8	-0.7
Diabetes (father)	1.1	1.4	6.1	-2.5	0.6	1.1	0.0	-2.3	-0.3	0.4	0.7	-0.3	-0.1
Diabetes (mother)	0.9	1.2	6.0	-0.2	0.2	0.6	-2.0	0.9	2.5	0.3	-0.8	-0.3	0.1
Severe depression (siblings)	0.5	0.5	2.8	0.7	0.2	-0.3	0.1	0.5	-1.7	0.3	1.0	0.5	0.5
Pack years adult smoking proportion	1.2	1.8	5.8	1.5	0.9	0.7	1.5	0.8	-2.4	0.9	1.9	0.8	0.5
Impedance of leg (right)	1.1	5.4	13.9	-1.4	-3.4	-3.7	0.4	-0.9	-0.2	-3.5	-0.7	-2.7	-2.3
Leg fat-free mass (left)	0.9	4.9	14.6	-2.2	1.9	2.4	0.1	-3.4	-1.9	1.9	3.8	0.6	0.6
Trunk fat percentage	0.7	2.7	9.4	-2.3	-1.0	-0.5	1.5	-3.1	-1.1	-1.9	0.6	-1.7	-0.9
Hand grip strength (right)	0.2	0.4	1.2	0.2	0.8	1.1	0.8	-0.2	-0.3	0.5	0.8	0.9	0.1
Townsend deprivation index at recruitment	0.9	1.3	2.6	0.8	1.6	1.4	-0.3	0.5	-1.0	1.2	1.0	1.3	1.4
Current tobacco smoking	0.4	0.7	1.6	-1.3	-0.1	0.4	1.2	-0.8	-1.1	-0.6	0.9	-0.5	-0.5
Average weekly fortified wine intake	0.5	0.6	2.1	0.3	0.4	-0.4	1.4	0.5	0.4	0.6	-0.6	0.3	1.4
Maternal smoking around birth	0.4	0.5	1.7	0.0	1.0	1.0	0.3	0.2	0.2	0.9	1.3	0.4	0.7
Fed-up feelings	1.4	2.5	5.2	1.0	2.3	2.2	1.3	1.1	0.2	2.0	-0.3	1.9	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	10.8	0.7	1.0	1.2	3.3	-0.1	-1.7	0.1	-0.5	0.9	1.0
Relative age voice broke	0.6	0.9	3.1	1.8	0.4	0.6	0.6	1.6	1.2	-0.3	-0.2	0.9	0.2
Taking other prescription medications	0.6	0.9	3.3	0.6	1.1	1.1	0.5	0.9	1.8	0.6	-0.9	0.8	0.5
Age when periods started (menarche)	0.3	0.8	2.2	0.5	1.2	0.8	-1.0	-0.2	-0.5	1.5	0.1	1.2	0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.3	1.8	1.1	1.3	0.6	1.0	-0.9	0.4	-0.0	1.4	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.0	1.1	-0.3	-0.2	-0.6	0.5	-1.4	0.1	0.7	0.2	-0.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	6.1	-0.5	0.2	0.3	-0.2	-0.2	-0.2	-0.4	-2.5	0.3	1.1
Qualifications: CSEs or equivalent	1.0	1.3	3.1	0.5	1.6	1.6	-0.5	-0.1	-1.0	1.5	-0.1	1.8	1.2
Serious illness, injury or assault to yourself	0.3	0.4	2.2	0.4	-0.4	-0.4	1.5	0.3	-0.3	-0.5	-0.8	0.2	-0.0
High blood pressure	0.5	1.3	4.8	0.7	-0.7	-1.0	-2.2	1.0	1.9	-0.8	-1.0	-0.7	-0.2
Hayfever, allergic rhinitis or eczema	1.4	3.0	10.0	-1.5	-2.0	-1.7	3.2	-1.9	-0.1	-1.7	-0.9	-1.3	-1.3
Multivitamins +/- minerals	0.7	0.9	2.7	0.2	-1.2	-1.4	-0.5	0.1	1.0	-0.5	0.9	-0.5	-1.6
Stomach or abdominal pain in last month	0.8	1.0	6.0	-0.2	-0.1	-0.1	0.8	-1.1	-2.5	-0.5	-1.2	0.4	-0.1
Supplements: Glucosamine	1.2	1.6	7.3	-0.8	-0.4	-0.7	-2.4	-0.4	2.7	0.5	-0.5	-0.5	-0.8
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.8	0.3	1.4	1.2	1.3	0.2	-0.2	0.9	-0.7	1.3	1.4
Medication: Atenolol	2.3	2.9	6.5	-1.8	-1.7	-2.2	0.2	-1.4	1.8	-1.2	-1.5	-2.5	-1.7
Medication: Levothyroxine sodium	0.1	0.2	0.6	-0.3	0.4	0.0	0.4	-0.8	0.4	0.5	0.8	0.3	0.4
Sitting height	1.1	7.6	23.8	-4.2	-0.4	-0.7	1.0	-4.9	-2.4	0.2	4.7	-2.2	-0.6
Chronic bronchitis/emphysema (father)	1.5	1.8	4.8	-0.9	1.5	1.0	-2.2	-0.9	-1.7	1.4	-0.3	0.6	1.6
High blood pressure (mother)	0.5	0.7	1.7	-0.8	1.2	1.3	0.0	-0.5	-0.1	0.9	-1.0	1.0	0.6
Body mass index (BMI)	0.3	1.2	3.0	-0.7	1.2	1.7	0.2	-1.7	-1.1	0.8	1.5	0.4	0.2
Impedance of leg (left)	1.1	5.2	13.6	-1.1	-3.4	-3.7	0.6	-0.5	0.6	-3.4	-1.5	-2.6	-2.1
Leg predicted mass (left)	1.0	5.0	15.0	-2.3	1.9	2.4	0.1	-3.5	-1.9	2.0	3.9	0.5	0.7
Trunk fat mass	0.7	2.9	11.6	-2.5	-0.3	0.3	1.4	-3.4	-1.3	-1.0	2.0	-1.2	-0.7
Waist circumference	0.5	1.7	6.9	-1.8	1.0	1.4	1.4	-2.6	-0.6	0.4	1.2	0.2	0.8
Number of incorrect matches in round	0.2	0.4	0.9	0.9	0.1	-0.6	0.6	0.6	-0.6	0.3	-0.6	0.3	0.9
Past tobacco smoking	0.3	0.6	3.7	-0.4	-0.7	-0.2	-1.9	-0.1	0.1	-0.3	-0.2	-0.6	-1.1
Alcohol usually taken with meals	0.3	0.4	1.9	-0.5	-0.6	-0.5	-1.4	-0.8	0.5	0.0	-0.8	0.2	-0.1
Nervous feelings	1.0	1.8	4.8	0.4	1.9	2.2	1.6	0.6	0.1	1.5	0.4	1.6	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	5.6	0.2	-0.0	0.3	2.4	-0.3	-1.4	-1.1	1.0	0.0	-0.2
Hearing difficulty/problems with background noise	1.3	2.1	16.5	0.2	0.7	0.9	4.1	0.5	0.9	-0.1	-1.1	0.5	0.8
Hair/balding pattern: Pattern 2	0.6	0.8	5.6	0.3	0.2	-0.2	0.8	0.4	1.1	0.1	-2.4	-0.1	0.5
Had menopause	0.6	0.8	1.7	-1.2	-0.7	-0.4	0.0	-0.8	0.9	-1.1	-1.3	-1.0	-0.1
Had other major operations	1.4	1.7	5.0	-1.4	1.5	1.4	0.8	-1.3	0.5	0.8	-1.1	1.3	2.2
Forced vital capacity (FVC)	0.4	1.7	7.2	-1.3	-0.8	-0.7	0.9	-1.6	-1.4	-0.2	2.7	-0.5	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.0	0.1	-0.4	-0.1	0.1	0.1	-1.0	0.1	0.9	0.0	-0.7
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	4.8	-0.2	1.9	1.6	1.2	0.1	-0.1	1.9	-0.8	1.1	2.2
Qualifications: None of the above	0.1	0.3	1.1	0.3	-0.0	-0.7	-1.1	0.1	0.2	0.5	-0.8	-0.2	-0.3
Financial difficulties in last 2 years	0.5	0.7	2.3	0.0	-0.3	0.4	1.5	0.7	1.5	-0.3	-0.6	-0.7	-1.1
Mouth/teeth dental problems	0.4	0.6	3.3	-0.0	-0.0	-0.5	-0.2	0.2	1.8	0.6	-1.2	0.1	0.9
Heart attack	0.8	1.1	3.7	-0.5	-0.4	-1.3	0.3	-0.9	1.9	0.1	1.3	-1.4	-0.6
Allergy	0.9	2.1	7.5	2.2	1.1	1.1	-1.8	2.7	0.5	0.7	0.5	1.2	0.9
Pain all over the body in last month	0.4	0.5	1.6	0.6	-0.4	0.2	-0.4	-0.5	-1.3	-0.3	0.7	0.0	-1.2
Diabetes (self-reported)	0.8	1.3	4.0	-2.0	-0.8	-0.9	-0.4	-1.7	-0.6	-0.8	-1.0	-1.5	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.9	0.0	-0.7	-0.6	1.0	-0.6	0.2	-0.4	0.4	-0.6	-0.8
Medication: Ramipril	1.5	1.9	4.9	-1.2	-1.7	-2.2	-0.3	-0.6	1.3	-1.0	-1.3	-2.0	-1.1
Medication: Simvastatin	1.2	1.8	3.9	-1.4	-0.8	-1.4	-0.0	-1.1	2.0	-1.1	-1.9	-1.8	0.0
Fluid intelligence score	1.1	2.3	5.2	1.3	-1.5	-1.1	2.3	1.6	2.2	-1.4	0.7	-1.1	-1.3
Illnesses of siblings	0.3	0.5	1.5	0.5	-0.2	0.1	1.2	-0.5	-1.1	-0.7	0.8	0.4	-0.4
Neuroticism score	0.5	1.0	2.4	-0.0	1.5	1.5	0.7	0.1	-1.2	1.1	0.2	1.1	1.0
Weight	0.8	3.9	13.6	-2.5	0.9	1.5	0.7	-3.7	-1.7	0.7	3.5	-0.2	0.0
Impedance of arm (right)	0.7	3.3	9.7	-1.1	-2.6	-2.8	0.8	-0.4	0.0	-3.1	-1.8	-1.8	-1.0
Arm fat percentage (right)	0.2	1.0	3.6	-1.3	-0.3	0.2	0.9	-1.9	-1.0	-1.1	0.6	-0.8	-0.5
Trunk fat-free mass	0.9	5.2	23.9	-2.4	1.5	1.9	0.3	-3.2	-1.4	2.0	4.9	0.0	0.1
Hip circumference	0.6	2.4	8.4	-1.8	0.5	0.9	1.2	-2.9	-1.4	0.1	2.9	-0.4	-0.1
Time employed in main current job	1.9	2.2	11.0	-1.1	0.7	0.4	3.3	-1.7	-1.7	-0.9	-1.2	0.1	1.0
Alcohol intake versus 10 years previously	1.2	1.8	6.2	0.2	1.1	0.5	-2.2	-0.1	1.1	2.5	-1.4	1.0	1.0
Father’s age at death	2.1	2.9	10.8	-0.8	1.5	2.3	3.3	-1.0	-1.9	0.5	0.8	1.4	1.5
Worrier / anxious feelings	0.2	0.3	1.4	-0.3	0.3	0.2	0.7	-0.3	-0.8	0.0	-1.2	0.1	-0.3
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	9.7	1.8	1.8	1.4	3.1	1.2	-0.1	2.1	-0.5	1.8	1.8
Falls in the last year	1.4	1.9	4.6	1.3	1.6	1.4	1.2	0.9	-0.8	1.5	0.1	2.1	1.6
Hair/balding pattern: Pattern 3	1.4	2.0	7.4	2.7	0.4	1.0	-1.3	2.6	-0.3	-0.0	0.6	1.6	0.1
Number of live births	1.1	1.6	3.6	0.1	1.6	1.9	1.0	0.1	-0.1	1.7	1.2	1.8	1.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	5.1	-0.0	-0.3	-0.1	0.5	-0.3	-0.6	0.5	2.2	0.4	-0.6
Pulse rate	0.8	1.4	3.1	0.3	1.8	1.7	0.7	0.3	-0.2	1.5	0.9	1.6	1.4
Happiness	0.4	0.5	4.0	0.0	0.4	0.5	2.0	0.0	-0.0	0.0	0.6	0.1	0.6
Noisy workplace	1.2	1.5	3.9	0.2	1.5	1.3	-0.5	0.2	-0.3	1.5	-2.0	1.5	1.4
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.1	0.3	0.2	0.9	0.1	-0.1	-1.2	-0.4	1.5	1.1	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.6	-0.1	-0.8	-0.8	0.4	-0.7	-0.3	-0.4	-0.1	0.1	-0.6
Mouth/teeth dental problems: Dentures	0.2	0.3	0.9	0.9	-0.2	-0.2	0.0	0.6	0.3	-0.7	-0.8	0.2	-0.3
Asthma	1.1	2.1	5.4	-0.2	2.3	2.0	-0.4	-0.6	0.3	2.1	1.3	1.4	1.6
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.8	-1.1	-1.7	-1.5	-0.5	-0.7	0.7	-0.7	-0.1	-1.5	-1.5
Medication: Cholesterol lowering	1.2	1.9	9.9	-0.2	-0.5	-0.9	0.9	0.5	3.1	-0.9	-1.8	-1.5	-0.5
Depression (self-reported)	0.3	0.3	1.3	-0.4	-0.3	-0.4	1.2	-0.2	0.3	-0.4	0.6	-0.8	-0.5
Medication: Lansoprazole	0.9	1.0	2.2	-0.9	1.3	0.9	1.3	-0.3	0.7	1.5	-0.2	1.0	1.3
Prospective memory result	0.8	0.9	4.5	-1.5	-0.4	-0.1	-2.1	-1.3	-0.5	-0.4	-0.6	-0.3	-0.3
Lung cancer (father)	0.5	0.6	3.0	-0.2	-0.7	-0.6	0.1	-0.0	-1.7	-0.7	-0.8	-0.6	-0.8
Illnesses of mother	0.5	0.7	2.2	1.5	-0.7	-0.3	0.9	1.2	-0.4	-0.8	0.9	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.7	-0.1	-1.3	-1.2	-0.7	-0.2	-0.2	-0.4	1.9	-0.6	-1.4
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	-0.5	0.2	0.6	0.9	-0.3	1.0	-0.9	-0.7	0.0	0.9
Impedance of arm (left)	0.8	3.8	9.4	-1.3	-2.6	-2.8	1.0	-0.8	0.4	-3.1	-2.6	-1.8	-0.9
Arm fat mass (right)	0.4	1.8	7.1	-1.7	0.4	0.8	0.4	-2.7	-1.2	-0.1	2.2	-0.5	-0.4
Trunk predicted mass	0.9	5.2	23.9	-2.4	1.5	1.9	0.2	-3.2	-1.3	2.0	4.9	-0.0	0.0
Standing height	0.7	7.2	24.2	-4.1	-0.6	-0.4	1.2	-4.8	-1.7	-0.2	4.9	-1.6	-0.6
Length of working week for main job	0.6	0.7	1.4	1.1	0.5	0.4	1.2	0.5	-1.1	0.3	1.2	0.8	-0.1
Exposure to tobacco smoke at home	1.9	2.2	11.0	1.1	-1.1	-0.9	3.3	1.7	1.0	-1.2	0.2	-1.2	-0.6
Breastfed as a baby	6.1	7.6	24.8	4.8	1.2	1.1	2.3	5.0	2.1	0.5	-2.4	2.4	1.9
Tense / ‘highly strung’	0.4	0.7	1.3	1.1	0.6	0.1	0.9	0.6	-1.1	0.7	0.7	1.0	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.8	7.2	1.0	2.2	1.2	1.4	0.5	-1.0	2.7	-0.7	2.0	2.5
Hair/balding pattern: Pattern 4	0.7	1.8	4.5	-1.8	-1.4	-1.0	-0.2	-1.5	0.1	-1.2	1.4	-2.1	-1.2
Birth weight of first child	1.4	2.5	4.3	-0.2	1.9	1.8	0.6	-1.9	-1.7	2.1	1.6	1.4	1.6
Peak expiratory flow (PEF)	0.1	0.2	1.1	0.2	-0.1	0.4	-0.3	0.3	-0.5	0.2	1.1	0.7	-0.4
Pulse wave reflection index	1.5	1.9	6.6	-1.2	-2.0	-1.2	0.7	-0.5	0.8	-2.6	-0.2	-1.6	-1.3
Ever highly irritable/argumentative for 2 days	1.3	1.6	4.8	-1.1	1.6	2.2	0.7	-1.2	-1.4	1.4	0.2	0.8	1.1
Loud music exposure frequency	1.0	1.1	5.8	-0.2	0.4	-0.0	1.5	-0.6	-2.4	0.1	-0.9	0.6	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	4.6	0.0	-0.1	1.0	-0.4	-0.1	-0.8	-0.4	2.1	0.5	-0.3
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	4.5	-0.4	1.6	1.9	1.4	-0.6	-2.1	0.2	0.3	1.0	0.9
Blood clot in the leg (DVT)	1.0	1.3	4.3	-1.8	0.8	1.0	-0.6	-2.1	-1.1	0.4	-0.6	0.4	1.1
Medication: Paracetamol	0.2	0.4	1.3	-0.4	-0.7	-0.5	-0.9	0.1	0.4	-0.1	0.7	-0.5	-1.1
Headache pain in last month	0.1	0.2	0.6	-0.8	0.2	0.6	-0.1	-0.6	0.1	-0.2	0.4	-0.4	-0.4
Medication for cholesterol, blood pressure or diabetes	0.8	1.2	6.9	0.8	0.5	0.9	-0.1	0.0	-2.6	0.8	1.2	1.3	0.5
Glaucoma (self-reported)	2.0	2.3	6.2	-0.4	-1.5	-1.9	-2.4	0.1	0.5	-0.8	-2.5	-1.8	-1.1
Gout (self-reported)	1.9	2.6	8.1	2.9	0.2	0.4	2.3	2.5	-0.5	-0.5	-1.7	1.4	0.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.0	0.8	1.1	0.9	0.0	0.6	1.4	1.4	0.7	0.9	0.6
Medication: Amlodipine	0.3	0.4	1.7	0.3	0.4	0.0	1.3	0.6	0.7	0.5	-0.4	0.2	0.6
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.8	-2.2	1.1	0.8	-1.5	-1.6	0.3	1.5	0.3	0.3	0.4
Birth weight	1.6	3.6	8.6	-1.7	1.8	1.6	-0.0	-2.3	-1.6	2.9	2.4	1.4	1.7
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	-0.4	0.7	0.7	0.4	-0.3	-0.1	0.5	-0.3	0.2	0.4
High blood pressure (siblings)	0.7	1.1	4.1	-1.0	-0.6	-1.1	-1.6	-0.2	0.6	0.2	-2.0	-1.1	-0.2
Forced vital capacity (FVC), Best measure	0.8	3.1	5.8	-1.5	-2.2	-1.9	-0.4	-1.6	-0.7	-1.4	2.4	-1.7	-2.4
Body fat percentage	0.5	1.8	6.7	-1.8	-0.7	-0.2	1.4	-2.6	-1.0	-1.6	0.6	-1.2	-0.8
Leg fat percentage (right)	0.3	1.2	5.3	-1.4	-0.4	0.0	0.8	-2.3	-1.0	-0.8	0.9	-0.8	-0.8
Arm fat-free mass (right)	0.9	4.5	18.7	-2.2	1.4	2.0	-0.1	-3.3	-1.3	1.8	4.3	0.1	-0.0
Exposure to tobacco smoke outside home	0.6	0.8	2.0	1.4	0.9	0.6	-0.6	1.0	-0.3	0.8	1.0	0.5	1.3
Comparative body size at age 10	0.2	0.5	2.2	-0.7	-0.0	0.5	-1.5	-0.6	0.8	0.0	0.7	-0.3	-0.5
Number of full brothers	1.6	2.1	5.6	0.2	2.3	2.4	-0.5	0.2	0.2	1.8	-0.5	1.4	2.1
Worry too long after embarrassment	0.3	0.5	2.7	0.3	0.1	-0.4	-1.6	0.9	0.3	0.3	-1.2	0.3	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.1	1.3	0.2	-0.3	1.7	1.5	1.8	0.2	-1.2	0.7	0.8
Wheeze or whistling in the chest in last year	0.6	1.1	2.3	0.3	1.4	1.3	1.4	0.1	-0.8	0.5	-1.0	1.1	1.5
Number of children fathered	1.8	2.0	6.6	-0.0	2.1	2.6	0.9	0.1	0.4	1.5	1.3	1.6	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.5	-1.1	-0.4	-0.5	-1.6	-0.6	0.6	0.0	0.2	-1.3	-0.9
Age at first live birth	0.4	0.6	1.4	-0.2	1.0	1.1	0.9	-0.5	-0.9	0.3	1.2	0.7	0.7
Pulse wave peak to peak time	0.4	0.5	1.4	0.3	-0.2	-0.7	-0.7	-0.0	-1.2	0.8	0.9	-0.2	-0.8
Health satisfaction	0.6	0.8	2.1	-0.9	0.3	0.0	0.6	-1.4	-0.9	1.2	-1.0	0.7	0.6
Shortness of breath walking on level ground	1.5	1.8	4.9	-0.5	1.6	1.5	1.1	-1.0	-0.8	2.2	-1.1	1.3	1.5
Qualifications: College or University degree	0.3	0.9	2.0	-1.4	-0.6	-0.4	1.3	-1.3	-1.3	-1.0	0.4	-0.5	-0.1
Eye problems/disorders: None of the above	1.6	1.8	4.6	0.9	1.7	1.8	1.1	0.6	-0.4	1.3	2.1	1.5	1.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.2	-0.1	-0.7	-0.1	0.2	0.8	0.6	-0.9	-0.5	-0.4	-1.1
Emphysema/chronic bronchitis	0.3	0.3	1.3	0.9	0.2	0.3	-1.1	0.8	0.2	0.5	-0.3	0.4	-0.5
Medication for pain relief, constipation, heartburn	1.1	1.8	4.4	-0.7	1.9	1.3	0.1	-1.1	-1.4	1.6	-0.1	1.5	2.1
Neck or shoulder pain in last month	0.9	1.3	3.3	0.3	1.3	0.7	0.2	0.6	1.7	1.8	-0.0	1.3	1.4
Medication: Blood pressure	0.2	0.4	2.5	0.1	0.4	0.2	-0.8	0.5	1.6	0.5	0.7	0.1	-0.0
Angina (self-reported)	0.7	1.0	2.6	-0.2	1.0	0.5	1.5	-0.3	1.3	0.8	-1.6	0.4	1.1
Migraine (self-reported)	0.6	0.7	3.2	-0.9	0.4	0.5	1.0	-0.1	1.3	0.3	-1.8	-0.3	0.2
Medication: Ibuprofen	2.3	2.8	5.9	-1.6	-2.4	-2.2	0.3	-1.0	0.8	-1.4	-0.5	-2.4	-2.2
Medication: Allopurinol	0.7	0.9	2.8	1.3	-0.0	0.4	1.4	1.7	-0.0	-0.3	-1.3	0.8	-0.4
Medication: Omeprazole	0.2	0.3	0.9	1.0	0.7	0.4	-0.2	0.7	-0.0	0.2	-0.1	0.2	0.7
Medication: Seretide 50 evohaler	1.5	1.8	7.2	-2.1	0.3	0.4	-1.4	-1.7	0.1	0.9	2.7	-0.4	0.0
Mean time to correctly identify matches	1.6	3.0	6.2	-0.7	-2.1	-1.9	1.0	-0.9	0.9	-2.5	-2.3	-2.0	-1.9
Heart disease (mother)	0.7	0.9	5.4	-0.1	-0.4	-0.4	-1.0	0.2	2.3	-0.5	-1.3	-0.6	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.0	1.7	-0.2	-0.6	-0.4	1.1	-0.3	0.2	-0.3	0.3	-0.4
Whole body fat mass	0.6	2.7	11.2	-2.3	-0.0	0.6	1.2	-3.3	-1.3	-0.7	2.3	-0.9	-0.7
Leg fat mass (right)	0.7	2.5	10.1	-2.0	0.5	1.1	0.7	-3.2	-1.6	-0.0	2.5	-0.4	-0.4
Arm predicted mass (right)	0.9	4.5	19.3	-2.4	1.3	1.8	0.1	-3.3	-1.2	1.6	4.4	-0.1	-0.2
Pulse rate, automated reading	0.6	1.9	4.5	-0.8	1.9	1.9	0.7	-1.2	-0.1	1.4	-0.1	1.6	2.1
Alcohol intake frequency.	1.4	3.2	6.9	2.5	0.7	0.5	-2.2	2.6	1.7	1.7	-2.3	1.3	0.6
Comparative height size at age 10	1.0	5.4	28.2	-2.3	-1.6	-0.9	1.1	-2.3	-0.5	-1.6	5.3	-2.1	-1.9
Number of full sisters	0.4	0.5	1.7	-0.6	0.8	1.0	0.5	-0.2	0.6	0.8	1.3	0.1	-0.2
Suffer from ‘nerves’	0.7	1.0	5.2	0.7	-0.2	0.1	2.3	0.5	-0.5	-0.6	1.5	-0.3	-1.2
Overall health rating	0.5	1.1	4.6	-0.4	1.0	0.7	0.8	-0.7	1.0	1.1	-2.2	0.5	1.2
Chest pain or discomfort	0.4	0.6	1.1	-0.3	1.1	1.0	0.5	-1.0	0.2	0.9	-0.6	0.8	0.9
Had major operations	0.6	0.7	3.3	-0.8	-0.7	-1.1	-0.1	0.2	1.8	-0.0	-0.0	-1.1	-0.5
Age at last live birth	1.7	2.5	6.5	0.8	2.4	2.5	1.0	0.6	-0.5	1.8	-0.1	1.8	2.0
Family relationship satisfaction	0.2	0.2	0.8	-0.3	0.2	0.3	-0.3	-0.4	-0.9	0.6	0.7	0.1	0.2
Leg pain on walking	1.0	1.2	5.8	-0.6	0.3	0.4	-2.4	-0.4	1.6	0.9	-1.5	0.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.9	0.7	1.2	1.2	-1.4	1.0	0.5	0.9	-0.7	0.4	0.9
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.1	-0.0	-0.8	-0.7	1.5	-0.4	-0.8	-1.4	1.0	-0.6	-0.7
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.9	-1.7	-0.1	0.1	-1.0	-1.7	-0.9	-0.9	0.7	-0.6	-0.2
Medication: Aspirin	0.7	1.0	2.1	-0.0	-1.3	-1.1	-0.7	0.1	0.7	-1.4	0.0	-1.3	-1.4
Supplements: Vitamin C	0.6	0.7	3.5	0.2	-0.7	-0.9	1.9	0.8	0.8	-0.0	1.0	-0.0	-0.6
Knee pain experienced in last month	0.7	1.0	5.6	0.1	0.8	0.5	1.2	-0.4	-0.1	1.2	-2.4	0.8	0.6
Hypertension (Self-reported)	0.5	1.3	6.6	0.6	-0.5	-0.9	-2.6	0.9	1.6	-0.6	-0.9	-0.6	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.7	1.3	0.9	0.9	1.0	1.4	1.6	0.4	-1.5	0.3	1.0
Illnesses of father: Heart disease	0.7	1.0	4.7	-0.1	0.1	-0.5	1.4	-0.1	2.2	0.1	-1.5	0.3	0.5
Illnesses of siblings: Diabetes	0.4	0.6	1.7	-0.9	0.8	1.3	0.0	-0.7	0.1	1.0	-0.3	0.6	0.8
Smoking status: Previous	0.5	0.8	1.8	0.6	1.2	1.0	1.3	0.5	0.1	0.7	0.3	1.0	1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	10.6	-1.7	-0.4	-0.0	0.8	-2.3	-2.3	-0.5	3.3	-0.8	-0.8
Whole body fat-free mass	0.9	5.4	20.6	-2.3	1.9	2.3	0.1	-3.3	-1.6	2.2	4.5	0.4	0.4
Leg fat-free mass (right)	0.8	4.4	12.3	-2.0	2.0	2.6	0.1	-3.1	-1.4	2.1	3.5	0.7	0.8
Arm fat percentage (left)	0.3	1.1	4.4	-1.4	-0.3	0.3	1.1	-2.1	-0.8	-1.1	0.3	-0.8	-0.6
Average weekly red wine intake	1.3	2.0	4.0	-1.2	-2.0	-2.0	-0.2	-0.9	1.3	-1.1	-0.9	-1.7	-1.7
Handedness (chirality/laterality): Left-handed	0.2	0.3	2.0	-0.3	0.2	0.4	1.4	-0.4	-0.2	0.3	0.3	0.4	-0.2
Mood swings	0.2	0.3	1.2	0.5	-0.4	-0.4	1.1	0.4	-1.0	-0.3	0.1	-0.1	-0.1
Loneliness, isolation	1.2	1.7	5.0	-0.6	1.5	1.3	2.2	-0.6	-1.2	1.0	-1.0	1.1	1.7
Long-standing illness, disability or infirmity	0.5	0.8	1.5	0.6	1.2	1.1	0.2	0.5	1.2	0.9	-0.4	0.9	1.2
Ever had bowel cancer screening	1.3	1.5	4.1	0.4	1.4	1.0	0.6	-0.4	-0.3	1.2	-2.0	1.6	1.7
Diabetes diagnosed by doctor	0.8	1.3	4.5	-2.1	-0.5	-0.5	-0.3	-1.8	-0.0	-0.8	-1.4	-1.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	6.5	1.9	1.1	1.0	-0.9	2.5	2.3	1.6	1.2	1.5	0.4
Friendships satisfaction	0.7	0.8	2.4	-0.4	1.2	1.0	0.1	-0.5	-0.1	1.6	0.4	0.9	1.4
Qualifications: nursing, teaching	0.2	0.3	1.9	-0.3	0.1	0.1	-1.4	0.2	0.8	-0.1	0.7	0.1	-0.1
Commuting to job workplace: Walk	0.6	0.6	2.2	0.9	0.4	0.2	1.5	1.0	0.0	-0.1	-0.8	0.8	0.9
Eye problems/disorders: Cataract	0.8	1.0	2.5	-1.2	-0.7	-0.7	-1.5	-1.1	1.6	-0.2	0.8	-0.6	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.4	-0.7	-1.5	-1.4	-0.8	-0.8	-0.7	-1.1	0.9	-1.6	-1.5
Medication for cholesterol	0.4	0.6	1.6	-0.3	0.7	1.3	0.6	-0.6	-1.0	0.9	1.2	0.5	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.1	5.2	0.8	1.7	1.4	0.8	1.1	0.7	1.5	-1.6	1.7	2.3
Back pain experienced in last month	2.5	3.6	8.2	-2.3	-2.4	-2.5	-1.0	-2.1	0.5	-1.8	-0.1	-2.9	-1.4
Mineral and other dietary supplements	1.9	2.5	12.3	1.3	0.9	1.1	1.9	0.8	-3.5	-0.1	1.5	1.1	1.2
Breast cancer (self-reported)	0.4	0.5	1.7	0.8	-0.4	-0.8	1.3	1.0	-0.1	-0.1	-0.3	-0.7	0.2
Asthma (self-reported)	0.8	1.5	4.0	-0.1	2.0	1.6	-0.5	-0.6	0.3	1.9	1.0	1.3	1.4
Osteoporosis (self-reported)	0.7	0.8	2.3	-1.5	0.8	1.1	-1.2	-0.9	0.5	1.2	-0.3	0.0	-0.0
Osteoarthritis (self-reported)	0.7	0.9	3.2	0.8	0.9	1.1	1.8	0.3	-0.6	-0.2	0.1	1.3	1.2
Medication: Aspirin	0.9	1.2	2.9	-0.1	-1.5	-1.2	-0.6	0.3	0.6	-1.7	-0.5	-1.4	-1.5
Medication: Gliclazide	1.2	1.4	2.6	-0.9	-1.3	-1.1	-0.5	-1.1	-1.4	-1.6	0.2	-1.2	-1.5
Illnesses of father: None of the above (group 1)	0.5	0.6	4.2	0.6	-0.0	0.3	0.2	-0.0	-2.0	-0.2	1.3	0.1	-0.3
Smoking status: Current	0.4	0.6	2.0	-1.4	-0.4	0.0	1.0	-0.8	-0.7	-0.8	0.4	-0.7	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.9	0.3	0.4	0.6	0.1	0.7	0.9	0.6	-0.7	0.8	0.2
Whole body water mass	0.9	5.2	21.2	-2.3	1.7	2.2	0.1	-3.3	-1.5	2.0	4.6	0.3	0.3
Leg predicted mass (right)	0.8	4.3	12.5	-2.0	1.9	2.5	0.0	-3.1	-1.4	2.1	3.5	0.7	0.7
Arm fat mass (left)	0.5	1.9	8.3	-1.9	0.3	0.8	0.5	-2.9	-1.2	-0.2	2.0	-0.7	-0.4
Number of self-reported non-cancer illnesses	0.9	1.5	4.9	0.8	1.0	0.6	0.5	0.8	2.1	0.4	-2.2	0.7	1.4
Average weekly champagne plus white wine intake	0.7	1.0	2.2	-0.1	-1.5	-1.4	-1.3	-0.5	-0.1	-1.0	0.3	-0.6	-1.4
Miserableness	0.2	0.4	1.5	0.1	-0.1	-0.4	1.2	0.7	0.7	-0.2	-0.9	-0.5	0.4
Guilty feelings	2.5	3.7	8.5	-0.0	2.4	2.0	-0.9	0.5	0.4	2.9	-2.7	2.1	2.4
Wears glasses or contact lenses	0.8	0.9	3.5	0.3	0.9	0.4	0.2	1.1	1.9	1.6	-0.7	0.3	0.6
Ever taken oral contraceptive pill	0.9	1.0	3.6	-1.1	0.7	1.0	1.9	-1.1	-1.0	-0.4	0.1	0.5	1.2
Hearing aid user	0.7	0.8	3.2	0.0	-0.2	-0.2	1.7	1.1	0.5	-0.6	-1.8	-0.5	-0.4
Mother’s age at death	0.8	1.0	2.9	-0.7	0.6	0.6	1.7	-1.3	-1.6	0.6	0.3	0.7	0.7
Financial situation satisfaction	1.3	1.6	7.5	-0.7	1.2	1.5	2.7	-1.0	-1.3	0.9	0.4	0.7	0.9
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.0	0.5	0.9	0.6	0.2	0.4	-0.4	1.4	0.8	0.8	0.4
Commuting to job workplace: Public transport	0.7	0.8	1.5	-1.2	-1.2	-0.7	-0.5	-0.6	-0.2	-1.2	-0.9	-1.1	-0.8
Eye problems/disorders: Glaucoma	1.8	2.1	4.8	-1.0	-1.8	-1.9	-1.1	-0.4	-0.4	-1.6	-1.6	-2.2	-1.4
Medication: Blood pressure	0.9	1.6	4.2	-0.1	-1.8	-2.0	-1.4	-0.1	0.1	-1.7	-1.0	-1.3	-1.3
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.4	-0.4	-0.6	-0.8	1.1	-0.3	-1.2	-0.7	-0.4	-0.6	-0.7
Supplements: Fish oil (including cod liver oil)	1.7	2.2	3.8	-1.5	-1.7	-1.8	-0.9	-1.7	1.5	-1.1	-0.5	-1.7	-2.0
High cholesterol (Self-reported)	1.7	2.9	15.3	0.3	-0.3	-1.1	1.9	0.6	3.9	-0.5	-2.8	-0.6	0.5
Medication: Bendroflumethiazide	1.4	2.2	5.1	-0.3	-2.3	-2.2	-0.5	0.2	0.7	-1.9	-0.5	-1.9	-1.9
Medication: Paracetamol	0.4	0.7	1.5	-1.1	-1.1	-0.8	-0.7	-0.5	-0.0	-0.8	0.4	-0.9	-1.2
Medication: Lisinopril	1.3	1.7	8.9	0.7	-0.2	-0.1	-3.0	1.1	1.5	0.6	1.5	0.1	-0.9
Medication: Atorvastatin	1.4	1.8	7.5	1.3	-0.2	-0.7	0.6	1.5	2.7	0.1	-2.3	0.1	0.2
Illnesses of father: High blood pressure	0.5	0.6	3.8	0.0	-0.3	-0.2	-0.4	0.4	1.9	0.2	-1.4	-0.2	-0.3
Alcohol drinker status: Never	1.0	1.2	4.6	1.1	0.3	0.4	-1.6	1.9	2.1	0.2	0.3	0.0	0.2
Ever smoked	0.5	0.9	4.9	-0.5	0.5	-0.0	2.2	-1.0	-0.4	0.3	-0.3	0.7	1.2
Basal metabolic rate	0.9	5.1	18.7	-2.4	1.6	2.2	0.2	-3.5	-1.6	1.8	4.3	0.2	0.3
Leg fat percentage (left)	0.2	0.8	4.4	-1.3	-0.2	0.1	0.7	-2.1	-0.5	-0.5	0.4	-0.6	-0.6
Arm fat-free mass (left)	0.8	4.1	18.6	-2.2	1.2	1.6	-0.5	-3.1	-1.1	1.7	4.3	-0.1	-0.1
Number of operations (self-reported)	1.0	1.4	3.4	0.7	1.3	1.6	0.2	0.3	1.8	1.1	-0.3	1.6	1.5
Average weekly beer plus cider intake	1.5	2.1	5.1	0.8	2.3	1.8	0.0	0.8	0.8	2.0	0.3	1.8	1.8
Irritability	1.1	1.9	5.0	1.2	1.5	1.5	1.3	0.6	-2.2	0.9	0.4	1.8	1.6
Risk taking	0.4	0.5	1.2	-0.6	-1.0	-1.1	0.8	-0.6	-0.7	-0.4	-0.1	-0.5	-0.9
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.5	-1.2	-0.1	-0.4	0.3	-1.2	-0.3	-0.2	-1.0	-0.1	0.7
Fractured/broken bones in last 5 years	1.6	2.1	3.7	-1.8	-1.6	-1.9	-0.0	-1.9	-0.9	-1.4	0.2	-1.7	-1.3
Age started oral contraceptive pill	0.3	0.4	1.0	-1.0	-0.2	-0.5	-0.2	-0.6	0.0	-0.7	-0.9	-0.4	0.8
Diastolic blood pressure, automated reading	0.4	1.4	3.6	0.5	-1.3	-1.4	-1.2	0.2	1.0	-1.9	-0.2	-1.2	-1.5
Ever depressed for a whole week	0.9	1.1	2.6	0.2	1.4	1.6	1.1	-0.1	-1.4	0.8	-0.3	1.2	1.0
Unable to work because of sickness or disability	1.0	1.3	3.1	-0.5	1.8	1.7	-0.8	-0.4	-0.2	1.7	-0.1	1.3	1.1
Commuting to job workplace: Cycle	1.2	1.5	9.9	0.6	0.6	0.7	-0.7	0.7	1.1	0.4	-3.1	1.0	0.6
Myopia	3.4	4.9	12.0	0.9	3.0	2.7	0.5	-0.4	-2.4	2.4	-0.1	3.5	2.8
Vascular/heart problems diagnosed by doctor	0.4	1.0	4.3	-0.2	0.3	0.7	1.1	-0.6	-2.1	0.7	1.5	0.6	-0.2
Cholesterol lowering medication	1.0	1.5	6.1	-0.7	-0.0	-0.8	-0.6	-0.4	2.4	0.3	-2.5	-0.4	1.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.0	1.0	0.6	0.3	0.5	0.5	-0.3	0.5	-0.3	0.2	0.6
Pain experienced in last month	0.4	0.7	2.3	1.4	0.4	0.6	-0.2	1.5	0.5	-0.1	0.1	1.0	0.9
Supplements: Calcium	1.0	1.1	8.4	0.0	-0.8	-1.0	0.2	0.1	0.9	-0.1	-2.9	-0.4	-0.4
Basal cell carcinoma (self-reported)	0.7	0.9	6.0	0.6	-0.2	-0.3	-0.6	1.2	2.5	0.3	-0.1	-0.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.6	-0.4	-0.4	-1.3	0.3	-0.8	1.9	0.1	1.2	-1.3	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.5	-1.5	1.1	1.1	-0.8	-1.9	-1.2	0.7	-0.6	0.6	1.3
Heart disease (siblings)	0.8	0.9	4.6	-0.4	0.9	0.5	-0.6	0.2	2.1	1.6	0.4	0.3	0.5
Alcohol drinker status: Previous	1.3	1.4	5.9	2.4	0.4	0.1	0.2	2.2	0.4	0.7	-1.1	1.2	0.3
Pack years of smoking	1.3	2.0	6.3	1.7	1.0	0.8	1.8	0.9	-2.5	0.9	1.6	0.9	0.7
Impedance of whole body	1.0	5.1	12.5	-1.2	-3.2	-3.5	1.0	-0.6	0.4	-3.5	-2.3	-2.3	-1.5
Leg fat mass (left)	0.6	2.2	9.2	-1.9	0.6	1.2	0.7	-3.0	-1.4	0.2	2.3	-0.2	-0.2
Arm predicted mass (left)	0.9	4.5	20.1	-2.2	1.3	1.8	-0.2	-3.2	-1.4	1.7	4.5	-0.0	-0.1