Hub : Genes

AGPAT9

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Nerve Tibial 0.1176 0.0416 2.1e-04 0.005 NA 0.000 NA 0.006 1.4e-01 NA 3.4e-01 NA 1.2e-01
2 GTEx Skin Not Sun Exposed Suprapubic 0.1440 0.0550 1.6e-03 -0.005 NA -0.005 NA -0.005 8.2e-01 NA 8.2e-01 NA 9.2e-01
3 METSIM Adipose 0.0437 0.0162 2.6e-04 0.047 0.022 0.027 0.019 0.035 1.1e-07 2.8e-04 5.4e-05 6.3e-04 5.1e-06
4 NTR Blood 0.0386 0.0125 4.2e-07 0.020 0.020 0.011 0.021 0.021 2.7e-07 3.1e-07 1.3e-04 2.2e-07 1.7e-07
5 YFS Blood 0.1175 0.0201 0.0e+00 0.145 0.162 0.171 0.170 0.165 4.8e-45 1.1e-50 1.9e-53 3.7e-53 9.6e-52
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0765 0.0475 3.3e-03 0.022 0.016 0.001 NA 0.012 1.6e-03 5.7e-03 2.5e-01 NA 1.3e-02
7 TCGA Brain Lower Grade Glioma 0.0434 0.0222 2.8e-05 0.023 0.048 0.053 NA 0.044 1.0e-03 3.8e-06 1.2e-06 NA 8.5e-06
8 TCGA Lung Adenocarcinoma 0.0588 0.0409 5.5e-03 0.009 0.007 0.007 NA 0.004 2.7e-02 4.6e-02 5.0e-02 NA 9.0e-02
9 TCGA Thyroid Carcinoma 0.0500 0.0210 1.8e-06 0.069 0.047 0.046 NA 0.046 3.1e-07 2.0e-05 2.5e-05 NA 2.4e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.9 1.5 2.6 -0.7 1.6 1.1 -1.3 -1.3 1.2 0.7 1.0 1.5
Bipolar Disorder or Schizophrenia 0.8 1.9 4.1 -2.0 0.2 -1.5 1.3 1.1 0.4 -1.8 -1.5 -1.4
Depressed Affect (Nagel 2018) 0.7 1.5 2.8 -0.7 -0.2 -1.5 1.6 1.6 -1.0 -0.8 -1.1 -1.7
Depression (Nagel 2018) 0.3 0.5 2.8 -1.7 1.0 -0.0 0.3 0.2 -0.2 0.2 0.5 -0.3
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.1 0.3 -1.4 -1.0 0.6 0.1 0.5 -0.8 -1.8 -0.8
Neuroticism (Nagel 2018) 0.3 0.7 1.9 -0.3 0.2 -1.1 1.3 1.4 -0.6 -0.2 -0.4 -1.0
Schizophrenia (2018) 2.8 5.8 9.2 -2.0 -1.1 -2.9 2.8 2.5 -0.4 -2.9 -2.7 -3.0
Schizophrenia vs Biploar Disorder 2.0 2.6 6.7 -1.8 -1.5 -1.1 1.2 1.0 -1.6 -1.7 -2.6 -1.7
Worry (Nagel 2018) 0.4 0.9 3.0 0.2 1.3 0.8 -0.9 -0.9 -0.8 1.7 0.0 1.0
Alzheimer’s Disease (in mother) 0.5 0.6 1.9 0.6 -0.5 -1.4 0.9 0.4 -0.4 -0.1 0.3 -1.2
Alzheimer’s Disease (in father) 0.8 0.9 2.5 -0.4 0.9 1.2 -0.8 -0.7 1.0 0.3 1.6 1.0
Alzheimer’s Disease (including proxy) 0.2 0.2 1.2 0.0 0.5 -0.2 -0.2 -0.5 0.4 0.5 1.1 0.1
Crohns Disease (2017) 0.5 1.2 1.9 1.0 1.4 0.8 -1.4 -1.2 0.6 1.3 1.1 0.9
Irritable Bowel Disease (IBD) 0.1 0.3 1.3 1.1 0.4 -0.5 0.0 0.4 0.8 -0.2 -0.2 -0.4
Ulcerative Colitis (UC) 0.8 1.5 3.0 1.0 -0.9 -1.5 1.4 1.7 0.5 -1.3 -0.7 -1.3
Major Depression (MDD) 0.5 0.6 2.0 0.3 1.1 0.9 -0.7 -0.5 -0.1 1.4 0.6 0.6
Reaction Time 0.4 0.7 1.7 -0.2 -0.6 -0.9 1.2 1.3 -0.2 -0.8 -0.7 -0.9
Verbal and Numeric Reasoning (VNR) 0.2 0.4 1.7 1.3 -0.2 -0.2 0.3 0.1 1.0 -0.3 -0.6 -0.0
Breast Cancer 2.9 7.1 20.0 -0.2 3.9 2.6 -2.7 -3.0 -1.1 4.5 1.1 1.8
Ovarian Cancer 0.2 0.3 0.9 0.9 0.2 -0.1 0.1 0.4 0.8 0.1 0.8 0.2
Prostate Cancer 0.4 0.5 1.9 -1.4 -0.3 -0.0 0.1 -0.1 -0.9 0.1 -1.3 -0.4
Age at First Birth 1.2 1.8 2.6 0.2 -1.3 -1.6 1.5 1.4 -0.6 -1.6 -1.5 -1.6
Bipolar Disorder (2011) 1.6 1.6 3.0 -0.3 1.7 1.4 -1.1 -0.6 1.2 0.7 1.7 1.7
Body Mass Index (BMI) (2010) 0.9 1.2 2.8 -0.1 -1.2 -1.0 1.1 0.9 -1.7 -0.3 -1.1 -1.5
Coronary Artery Disease (CAD) 0.6 0.7 2.6 -0.9 -0.6 -0.9 0.8 0.4 -1.6 0.3 -0.2 -1.1
Crohns Disease (2012) 0.5 0.8 2.5 1.6 0.7 0.3 -0.7 -0.4 1.3 0.1 1.2 0.7
Mean Putamen Volume 0.4 0.5 1.0 0.2 -0.0 -1.0 0.8 1.0 0.3 -0.9 -0.4 -0.5
Fasting Glucose 0.3 0.4 1.9 -0.6 0.5 0.3 -0.0 -0.1 -1.1 1.4 0.2 -0.0
HbA1C 1.0 1.2 4.1 1.2 2.0 0.4 -0.3 -0.1 -0.9 1.8 0.8 0.1
HDL Cholesterol 0.1 0.2 0.5 0.3 -0.4 -0.1 0.2 0.7 0.4 -0.5 -0.0 0.3
LDL Cholesterol 1.1 1.7 4.5 0.4 -2.1 -1.2 1.4 1.7 -0.8 -1.4 -0.9 -1.1
Lupus 0.0 0.0 0.2 0.2 0.3 0.0 0.0 -0.1 0.4 0.1 0.1 0.2
Neuroticism (2016) 0.8 1.1 2.4 0.1 0.8 1.2 -0.8 -0.6 1.5 0.4 1.5 1.4
Primary Biliary Cirrhosis 1.2 1.7 9.2 3.0 -0.1 -0.7 0.9 1.4 1.1 -1.2 0.6 -0.5
Rheumatoid Arthritis 0.9 1.3 3.6 -1.9 -0.8 -1.0 0.9 0.6 -0.6 -1.0 -1.5 -1.2
Schizophrenia (2014) 1.9 4.1 9.7 -3.1 -0.9 -1.8 1.7 1.4 -0.9 -2.5 -2.6 -2.1
Triglycerides 0.1 0.2 0.7 0.1 0.2 0.2 -0.1 0.2 0.6 -0.5 0.8 -0.1
Type 2 Diabetes (T2D) (2012) 1.5 1.8 6.0 -1.1 2.4 0.6 -1.4 -1.6 0.3 1.7 0.6 0.7
Ulcerative Colitis 0.0 0.1 0.1 0.1 -0.4 -0.1 0.0 0.3 0.3 -0.1 -0.2 -0.2
Blood Eosinophil Count 0.2 1.4 3.0 0.9 -0.1 -1.4 1.6 1.7 0.9 -1.5 0.7 -1.1
Blood Platelet Count 0.1 0.7 2.8 0.2 -0.1 -0.6 0.7 1.0 0.8 -1.7 0.2 -0.8
Blood Red Count 0.1 1.4 3.1 1.2 1.6 1.1 -0.9 -0.8 1.8 0.1 1.2 1.2
Blood White Count 0.6 4.3 8.4 0.1 -1.9 -2.5 2.4 2.6 0.4 -2.9 -1.9 -2.0
Heel T-Score 0.7 5.9 18.7 -2.9 -1.2 -1.5 1.0 -0.3 -3.7 -1.3 -4.3 -2.4
BMI 0.0 0.2 0.7 -0.1 0.1 -0.2 0.3 0.8 -0.3 -0.6 -0.4 -0.3
Height 0.1 2.3 5.8 1.3 0.9 2.4 -2.0 -1.5 1.1 0.4 1.1 1.9
Waist Hip Ratio (WHR) 1.2 5.6 12.1 0.3 1.6 2.9 -2.8 -2.9 -0.6 3.5 2.1 2.5
Systolic Blood Pressure 1.8 9.0 14.5 0.5 3.3 3.8 -3.5 -3.1 0.9 3.8 2.7 3.3
Smoking Status 0.2 0.4 1.7 -0.5 -0.1 0.3 -0.4 0.2 0.7 0.5 1.3 1.0
Allergy or Eczema 0.3 0.8 4.5 2.1 0.2 0.1 0.3 0.2 0.5 1.0 0.9 0.1
Cardiovascular Disease 0.2 0.6 3.0 0.2 0.3 -0.2 0.3 0.2 -1.7 1.0 -0.6 -0.6
Hypothyroidism (self reported) 1.0 2.4 4.5 -0.8 -1.9 -1.6 1.5 1.4 -2.1 -0.3 -2.1 -1.4
Respiratory disease 1.3 3.0 5.4 -0.7 -1.2 -2.2 2.0 1.6 -1.4 -1.0 -2.3 -2.2
Type 2 Diabetes (T2D) (2018) 1.2 2.2 10.3 -3.2 -0.2 -0.5 0.4 -0.1 -2.1 -0.2 -1.9 -1.1
Lung FEV1/FVC ratio 1.2 6.0 12.7 -1.2 -3.6 -2.4 2.5 2.8 -0.2 -3.3 -1.6 -2.6
Lung FVC 0.1 0.5 1.3 -0.3 0.4 -1.0 1.1 1.0 0.1 0.8 -0.3 -0.8
Neuroticism 0.1 0.3 1.2 -0.4 1.1 -0.1 0.5 0.9 -0.4 -0.2 -0.4 -0.5
Chronotype (morning person) 0.7 1.7 3.8 -0.3 -1.7 -1.5 1.5 1.0 -1.2 -0.7 -1.1 -2.0
Hair Pigment 0.1 1.8 6.7 2.6 1.0 0.5 -0.8 -0.5 1.0 0.5 2.2 1.1
Tanning 0.2 2.1 6.6 -0.9 1.0 1.0 -1.2 -1.6 -2.6 2.3 0.2 0.4
Hand grip strength (left) 0.5 1.2 3.6 -1.1 -1.0 -0.7 0.8 0.7 -1.9 0.2 -1.6 -1.0
Number of treatments/medications taken 0.6 1.1 3.8 1.3 1.2 0.5 -0.6 -0.8 -1.1 2.0 0.4 0.3
Average weekly spirits intake 0.6 0.7 2.6 0.4 1.6 0.6 -0.7 -0.6 -0.1 1.4 0.5 0.5
Sensitivity / hurt feelings 0.7 1.2 2.9 -1.7 -0.7 -0.9 1.2 1.4 -0.7 -1.0 -0.5 -1.1
Frequency of depressed mood in last 2 weeks 0.4 0.5 2.9 -1.7 1.0 0.2 -0.3 -0.3 -0.7 0.4 0.2 0.0
Hearing difficulty/problems: Yes 0.1 0.2 0.5 -0.5 -0.3 -0.1 0.2 0.3 0.7 -0.7 -0.4 -0.1
Relative age of first facial hair 1.4 2.9 6.1 2.0 2.5 1.2 -1.3 -0.9 1.6 1.2 2.2 1.6
Other serious medical condition/disability diagnosed by doctor 2.6 3.4 6.8 0.1 2.6 1.8 -2.0 -2.3 -0.1 2.6 1.4 1.6
Ever used hormone-replacement therapy (HRT) 3.3 4.2 8.5 -1.2 -2.9 -2.0 2.7 2.7 0.2 -2.3 -1.1 -1.8
Ever had hysterectomy (womb removed) 0.6 0.7 1.4 -0.5 1.2 0.8 -0.9 -0.9 0.4 1.0 0.7 0.7
Systolic blood pressure, automated reading 3.0 8.8 13.6 1.5 3.2 3.7 -2.9 -2.3 1.7 3.5 3.6 3.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 0.7 -0.0 0.4 0.8 -0.5 -0.8 -0.0 0.8 0.7 0.2
Angina 0.5 0.7 2.0 0.8 1.4 0.6 -0.7 -0.9 0.6 0.6 0.8 0.4
Medication for hormone replacement therapy 0.4 0.5 1.8 0.6 -0.6 1.1 -0.5 -0.4 0.0 0.0 1.4 0.4
Vitamin and mineral supplements 1.0 1.4 2.8 -1.7 -1.4 -1.1 1.2 1.5 -0.1 -1.1 -1.0 -0.8
Supplements: Zinc 0.5 0.5 2.0 1.3 0.2 0.3 -0.1 -0.1 1.0 -0.1 1.4 0.2
Medication: Co-codamol 1.2 1.4 4.3 2.1 0.7 0.7 -0.3 0.3 1.4 -0.6 2.0 0.7
Medication: Metformin 1.7 2.4 8.1 -2.9 -0.6 -1.6 1.1 0.7 -1.1 -1.0 -2.0 -1.7
Diabetes (father) 1.1 1.3 2.9 -1.3 0.7 0.9 -1.3 -1.2 -0.3 1.7 1.4 0.9
Diabetes (mother) 0.5 0.7 3.3 1.8 -0.9 -0.1 0.6 0.6 -0.6 -0.1 -1.0 -0.1
Severe depression (siblings) 0.3 0.4 1.7 -1.3 -0.0 -0.4 0.4 -0.2 0.6 -0.2 -1.0 -0.3
Pack years adult smoking proportion 0.2 0.3 0.7 -0.4 -0.4 -0.4 0.8 0.9 -0.0 0.3 -0.3 -0.5
Impedance of leg (right) 0.3 1.3 2.6 -0.5 0.5 1.3 -1.3 -1.0 1.5 0.0 1.6 1.6
Leg fat-free mass (left) 0.0 0.1 0.3 0.4 0.5 0.5 -0.4 -0.2 -0.0 -0.1 -0.4 0.1
Trunk fat percentage 0.1 0.2 0.4 -0.6 0.6 0.5 -0.5 -0.0 0.5 -0.6 0.2 0.6
Hand grip strength (right) 0.5 1.3 2.3 -0.8 -1.3 -0.8 1.2 1.2 -1.3 -0.4 -1.5 -1.4
Townsend deprivation index at recruitment 0.6 0.8 5.6 -2.4 0.5 0.1 -0.2 0.2 -0.6 0.9 0.3 0.1
Current tobacco smoking 1.1 1.8 3.6 -1.5 0.9 1.5 -1.7 -1.5 0.0 1.1 0.9 1.9
Average weekly fortified wine intake 1.3 1.5 3.5 -0.6 0.4 1.9 -1.5 -1.4 -0.4 1.1 1.6 1.1
Maternal smoking around birth 0.4 0.5 1.8 -0.9 -0.8 -0.2 0.3 0.1 -1.1 -0.5 -1.3 -0.3
Fed-up feelings 0.7 1.2 2.7 -0.2 -0.9 -1.2 1.2 1.2 -1.6 -0.3 -0.9 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 2.2 -1.5 0.2 -0.6 0.6 0.5 0.3 -0.9 0.2 -0.6
Relative age voice broke 1.9 2.9 5.2 1.8 1.7 1.5 -1.8 -1.8 1.2 1.2 2.3 1.7
Taking other prescription medications 0.3 0.4 1.1 0.2 0.6 -0.8 1.0 1.0 -0.0 0.3 0.3 -0.7
Age when periods started (menarche) 0.9 2.3 4.8 0.3 1.6 1.5 -1.5 -1.3 0.8 1.8 2.2 1.7
Bilateral oophorectomy (both ovaries removed) 2.9 3.4 7.2 0.3 2.7 2.0 -1.8 -1.8 1.2 2.3 1.7 1.7
Heel bone mineral density (BMD) T-score, automated (left) 1.7 3.8 8.5 -1.7 -2.1 -1.5 1.3 1.0 -1.9 -2.3 -2.9 -2.0
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.9 -0.2 -0.9 -0.0 -0.3 -0.4 -0.2 0.5 -0.8 0.6
Qualifications: CSEs or equivalent 0.2 0.2 0.8 0.2 -0.0 0.7 -0.6 -0.0 0.4 0.3 0.4 0.9
Serious illness, injury or assault to yourself 0.2 0.2 0.5 -0.5 0.3 0.4 -0.5 -0.6 0.7 -0.4 0.1 0.5
High blood pressure 0.2 0.7 2.5 0.0 1.6 0.8 -0.6 -0.3 -0.8 1.2 0.6 0.3
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.1 1.1 0.4 -0.7 0.8 0.7 0.3 0.5 0.4 -0.6
Multivitamins +/- minerals 0.4 0.5 1.7 1.3 0.5 0.5 -0.8 -1.2 0.4 0.3 0.5 0.4
Stomach or abdominal pain in last month 0.2 0.2 0.5 -0.0 -0.4 0.7 -0.5 -0.5 -0.5 -0.4 -0.7 0.4
Supplements: Glucosamine 1.5 1.9 11.2 3.4 -0.2 -0.6 0.7 1.1 0.9 -1.6 0.4 -0.6
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 4.1 2.0 1.1 0.6 -0.1 -0.0 1.0 0.2 0.6 0.1
Medication: Atenolol 3.0 3.8 5.9 -0.6 1.9 2.2 -2.2 -2.1 0.0 2.4 2.3 2.1
Medication: Levothyroxine sodium 1.8 3.0 4.6 -0.0 -2.0 -2.0 2.0 2.1 -1.8 -0.8 -1.6 -2.1
Sitting height 0.5 3.5 6.1 0.9 2.3 2.5 -2.5 -2.2 1.5 0.7 1.5 1.9
Chronic bronchitis/emphysema (father) 0.5 0.6 2.5 -1.6 -0.4 -0.3 0.1 0.3 -1.1 -0.1 -1.0 -0.7
High blood pressure (mother) 0.2 0.2 0.7 -0.4 -0.2 -0.4 0.2 -0.0 -0.9 0.4 -0.8 -0.4
Body mass index (BMI) 0.2 1.0 1.9 -0.8 -0.7 -0.9 1.0 1.3 -0.5 -1.3 -1.4 -0.8
Impedance of leg (left) 0.3 1.2 2.4 -0.8 0.4 1.2 -1.3 -1.1 1.5 -0.0 1.3 1.5
Leg predicted mass (left) 0.0 0.1 0.2 0.5 0.3 0.4 -0.3 -0.1 -0.0 -0.3 -0.3 -0.0
Trunk fat mass 0.1 0.2 0.4 -0.6 0.6 0.5 -0.4 -0.0 0.4 -0.7 0.0 0.4
Waist circumference 0.2 0.8 1.5 0.1 0.9 1.2 -0.9 -0.5 0.6 0.8 1.2 1.1
Number of incorrect matches in round 0.1 0.2 1.4 0.8 -0.0 0.2 0.1 -0.2 0.1 0.2 1.2 -0.0
Past tobacco smoking 0.3 0.6 1.8 -1.3 -0.0 -0.1 0.1 -0.5 -1.3 0.7 -0.9 -0.7
Alcohol usually taken with meals 0.2 0.3 1.3 -0.4 -1.1 0.1 0.2 0.4 -0.9 0.1 -0.2 -0.3
Nervous feelings 0.9 1.6 5.3 0.0 2.0 0.9 -1.1 -1.2 -0.4 2.3 0.2 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 1.5 -0.1 1.2 0.8 -0.9 -0.2 1.0 -0.1 1.2 1.2
Hearing difficulty/problems with background noise 2.6 4.1 6.6 0.9 1.8 2.4 -2.5 -2.2 1.6 1.4 2.1 2.6
Hair/balding pattern: Pattern 2 0.2 0.3 0.8 0.9 -0.8 -0.2 0.3 0.6 -0.1 -0.2 0.6 -0.1
Had menopause 11.6 14.5 29.0 0.4 -5.1 -4.0 5.0 5.4 -0.3 -4.1 -1.8 -3.8
Had other major operations 0.2 0.2 1.0 0.2 0.2 0.4 -0.0 0.0 -0.6 1.0 0.2 0.2
Forced vital capacity (FVC) 0.0 0.1 0.7 0.9 0.3 0.1 0.0 0.2 0.4 0.0 0.3 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 4.0 -1.5 -1.2 -0.3 0.2 -0.0 -1.2 -1.5 -2.0 -0.8
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 1.4 -0.8 0.7 1.1 -1.0 -1.2 -0.3 1.2 0.4 1.0
Qualifications: None of the above 0.8 1.8 8.2 -2.9 -0.1 -0.8 0.8 0.5 -1.8 0.6 -1.5 -0.8
Financial difficulties in last 2 years 0.3 0.5 1.7 -0.9 -0.4 -0.6 0.0 -0.1 -1.3 0.8 -0.7 -0.4
Mouth/teeth dental problems 0.8 1.2 2.5 -0.8 -1.3 -1.1 1.4 1.6 0.5 -1.2 -0.3 -0.9
Heart attack 2.0 2.5 4.2 -1.3 1.4 1.8 -2.0 -1.8 -0.5 1.8 1.1 2.0
Allergy 0.6 1.3 2.9 0.4 0.3 1.7 -1.4 -1.1 1.1 0.1 1.2 1.7
Pain all over the body in last month 0.6 0.6 1.9 -1.3 -0.3 -0.3 0.3 0.4 -1.4 0.3 0.8 -0.9
Diabetes (self-reported) 0.4 0.6 2.6 -1.6 -0.1 -0.4 0.4 0.1 -1.1 -0.1 -0.6 -0.8
Hayfever/allergic rhinitis (self-reported) 0.6 0.9 3.1 1.8 1.0 0.1 -0.1 -0.2 0.5 0.6 1.7 0.1
Medication: Ramipril 0.6 0.8 1.5 -0.3 0.6 -1.2 0.9 1.0 1.2 -0.8 0.8 -0.9
Medication: Simvastatin 0.2 0.3 1.5 -0.2 -0.5 0.4 -0.1 0.3 -0.0 0.9 1.2 0.4
Fluid intelligence score 0.3 0.6 3.5 1.1 0.3 0.2 -0.2 -0.3 1.9 -0.2 0.4 0.3
Illnesses of siblings 1.0 1.3 2.0 -0.8 -1.4 -1.1 1.2 1.2 -1.2 -0.9 -1.2 -1.4
Neuroticism score 0.3 0.6 3.4 -0.3 1.8 0.8 -0.6 -0.3 -0.3 0.9 0.3 0.5
Weight 0.0 0.2 0.5 -0.2 0.5 0.5 -0.2 0.1 0.5 -0.7 -0.2 0.2
Impedance of arm (right) 0.7 3.1 6.6 0.8 1.6 1.7 -1.8 -1.6 2.3 0.6 2.6 1.9
Arm fat percentage (right) 0.1 0.3 0.8 -0.9 0.1 -0.2 0.2 0.6 0.4 -0.9 -0.2 0.0
Trunk fat-free mass 0.0 0.1 0.2 0.2 0.2 0.2 0.0 0.2 0.1 -0.4 -0.4 -0.2
Hip circumference 0.2 0.7 2.2 0.1 -0.1 -0.7 0.8 1.3 1.1 -1.5 -0.1 -0.4
Time employed in main current job 1.3 1.5 6.1 2.5 0.5 1.2 -1.2 -1.1 -0.4 0.8 1.4 0.8
Alcohol intake versus 10 years previously 1.7 2.6 5.3 -0.4 -1.7 -1.8 1.8 1.8 -0.2 -2.3 -1.4 -1.8
Father’s age at death 0.3 0.4 1.9 -0.4 1.4 0.2 -0.2 -0.6 -0.4 0.9 0.6 -0.3
Worrier / anxious feelings 0.1 0.2 0.4 -0.2 0.2 0.6 -0.5 -0.3 -0.6 0.3 0.4 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.2 -0.8 -0.7 -1.1 0.9 1.1 -0.4 -1.5 -1.5 -1.0
Falls in the last year 0.8 1.0 3.5 -1.9 -1.5 -0.5 0.8 0.9 0.0 -1.0 0.7 -0.6
Hair/balding pattern: Pattern 3 0.4 0.6 2.5 -0.6 0.6 -0.1 -0.1 -0.2 -1.4 0.2 -1.6 -0.1
Number of live births 0.2 0.3 0.8 -0.1 -0.9 0.0 0.2 0.3 -0.9 0.8 0.7 0.3
Forced expiratory volume in 1-second (FEV1) 0.1 0.5 0.9 0.1 -0.9 -0.6 0.8 0.7 0.1 -0.9 -0.6 -0.9
Pulse rate 1.8 3.1 11.0 -2.6 -0.9 -0.7 0.4 0.0 -3.3 0.3 -2.8 -0.8
Happiness 0.9 1.0 2.3 -0.6 -0.3 -1.0 1.1 1.4 1.1 -1.5 -0.2 -1.1
Noisy workplace 0.5 0.7 2.6 -0.8 -0.4 -0.3 0.2 -0.2 -1.6 0.0 -1.4 -0.6
Qualifications: A levels/AS levels or equivalent 0.4 0.9 3.2 1.3 -0.6 0.2 -0.1 -0.1 1.5 -1.8 0.6 0.2
Serious illness, injury or assault of a close relative in last 2 years 1.6 1.8 3.2 0.7 1.1 1.7 -1.5 -1.1 -0.7 1.8 1.6 1.4
Mouth/teeth dental problems: Dentures 1.4 2.4 3.6 1.5 1.6 1.9 -1.9 -1.9 -0.6 1.6 0.9 1.6
Asthma 1.3 2.6 4.6 -0.8 -1.3 -1.9 1.7 1.5 -2.0 -0.6 -2.1 -1.9
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.3 0.8 0.4 0.9 -1.1 -1.2 -0.8 1.5 0.1 0.8
Medication: Cholesterol lowering 0.4 0.6 1.9 -1.3 0.1 0.4 -0.5 -0.4 -1.4 1.2 0.2 0.2
Depression (self-reported) 0.9 1.0 6.1 -2.5 -0.8 0.1 -0.4 -0.5 -0.6 -0.9 -1.0 0.2
Medication: Lansoprazole 0.4 0.4 1.2 -0.7 0.9 -0.5 0.6 0.2 -0.3 0.4 -1.1 -0.6
Prospective memory result 0.0 0.0 0.2 -0.1 -0.1 0.1 -0.1 -0.1 -0.4 0.1 -0.3 0.2
Lung cancer (father) 0.2 0.2 1.0 -0.5 -1.0 -0.3 0.5 0.4 -0.2 -0.4 0.2 -0.1
Illnesses of mother 0.2 0.2 1.2 0.3 0.0 0.0 0.1 0.4 1.1 -0.8 -0.2 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.0 -1.0 -1.4 -0.7 0.8 0.7 -0.7 -1.0 -1.0 -1.2
Pulse wave Arterial Stiffness index 2.0 2.3 8.8 -1.7 -0.8 -0.0 -0.2 -0.8 -3.0 0.4 -2.7 -0.6
Impedance of arm (left) 0.5 2.3 4.1 0.6 1.3 1.6 -1.8 -1.5 1.7 0.7 2.0 1.8
Arm fat mass (right) 0.0 0.2 0.8 -0.9 0.1 0.1 0.0 0.4 -0.0 -0.9 -0.4 0.0
Trunk predicted mass 0.0 0.1 0.3 0.1 0.2 0.2 0.1 0.2 -0.0 -0.5 -0.5 -0.2
Standing height 0.4 3.9 6.7 0.9 2.2 2.6 -2.5 -2.3 1.6 1.1 1.9 2.0
Length of working week for main job 0.6 0.7 1.5 1.2 0.9 0.5 -0.6 -0.4 0.8 1.0 1.0 0.4
Exposure to tobacco smoke at home 4.0 4.4 7.0 -2.2 -1.8 -2.4 2.4 1.7 -2.5 -0.0 -1.9 -2.6
Breastfed as a baby 1.1 1.4 2.5 -0.8 -1.2 -1.2 1.6 1.5 -0.8 -0.7 -0.9 -1.5
Tense / ‘highly strung’ 0.2 0.3 1.2 -0.2 0.7 0.5 -0.3 -0.3 -1.1 0.9 -0.1 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.5 -0.2 1.2 -0.3 -0.1 0.4 0.3 -0.2 0.7 -0.1
Hair/balding pattern: Pattern 4 0.3 0.6 2.2 1.2 1.5 0.4 -0.6 -0.4 0.9 0.3 0.4 0.3
Birth weight of first child 0.5 0.9 2.0 -0.8 1.1 1.1 -1.1 -1.4 -0.5 1.1 0.1 0.6
Peak expiratory flow (PEF) 0.1 0.3 2.5 1.6 0.0 0.2 -0.1 -0.2 0.3 0.0 0.3 -0.2
Pulse wave reflection index 0.3 0.3 1.1 1.1 -0.2 -0.3 0.3 0.2 -0.7 0.3 -0.8 -0.4
Ever highly irritable/argumentative for 2 days 1.0 1.2 3.0 -0.9 -0.9 -1.0 1.1 1.7 -0.9 -1.2 -1.2 -0.8
Loud music exposure frequency 1.4 1.6 2.9 1.3 1.0 1.5 -1.5 -1.6 1.0 0.6 -0.4 1.7
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 3.9 2.0 -0.2 0.7 -0.8 -0.8 1.1 -0.7 1.0 0.8
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.9 -0.4 -0.3 -0.5 0.7 0.6 1.4 -0.9 0.3 -0.6
Blood clot in the leg (DVT) 0.3 0.3 1.1 -0.1 1.0 0.1 -0.2 -0.0 -0.9 0.9 -0.2 -0.2
Medication: Paracetamol 1.4 2.3 5.5 1.0 1.0 1.5 -1.8 -1.6 -1.5 2.4 0.6 1.5
Headache pain in last month 0.8 1.3 2.0 0.2 -1.3 -1.1 1.4 1.3 -1.2 -1.0 -1.2 -1.3
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 2.9 0.7 -1.4 -0.8 1.0 0.9 1.0 -1.7 -0.2 -0.6
Glaucoma (self-reported) 0.9 1.0 3.2 -0.2 1.0 0.7 -0.6 -0.1 1.7 -0.0 1.8 1.0
Gout (self-reported) 0.9 1.3 2.7 -0.3 1.6 1.4 -1.1 -0.6 0.6 1.4 1.3 1.2
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 2.4 0.2 -1.5 -1.5 1.5 1.5 -1.2 -0.4 -1.1 -1.3
Medication: Amlodipine 1.7 2.4 7.0 0.6 -0.8 -1.9 2.0 2.7 0.0 -1.8 0.0 -1.7
Medication: Ventolin 100micrograms inhaler 1.9 2.4 3.5 -0.1 -1.6 -1.9 1.9 1.7 -1.5 -1.3 -1.6 -1.6
Birth weight 0.3 0.6 2.4 1.6 0.4 0.9 -0.6 -0.4 0.1 0.6 1.1 0.4
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.2 1.0 0.9 0.7 -0.7 0.0 0.5 0.4 1.1 1.0
High blood pressure (siblings) 0.1 0.1 0.4 0.7 0.1 0.4 -0.2 -0.5 -0.0 0.4 -0.1 0.1
Forced vital capacity (FVC), Best measure 0.0 0.1 0.2 -0.4 -0.2 0.1 0.0 0.1 -0.4 0.1 -0.0 -0.3
Body fat percentage 0.1 0.2 0.5 -0.7 0.5 0.5 -0.4 0.1 0.5 -0.7 0.1 0.6
Leg fat percentage (right) 0.1 0.4 1.8 -1.3 0.2 -0.0 0.1 0.7 0.6 -0.7 0.0 0.4
Arm fat-free mass (right) 0.0 0.2 0.6 0.3 -0.2 0.2 0.2 0.4 -0.6 -0.4 -0.8 -0.3
Exposure to tobacco smoke outside home 0.9 1.3 2.3 -0.3 -1.5 -1.2 1.2 1.0 -1.1 -1.0 -0.6 -1.5
Comparative body size at age 10 0.7 2.0 4.9 -0.2 -2.2 -1.7 1.3 0.9 -0.6 -1.7 -1.4 -1.4
Number of full brothers 0.2 0.2 0.5 -0.3 -0.7 0.4 -0.3 -0.4 -0.6 0.3 -0.6 0.3
Worry too long after embarrassment 0.5 0.8 1.5 1.0 1.1 1.2 -0.7 -0.4 0.6 0.6 0.6 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 3.9 -2.0 -0.9 -0.5 0.4 0.4 0.2 -0.7 -0.2 -0.2
Wheeze or whistling in the chest in last year 0.2 0.3 2.0 0.1 -0.1 -0.4 0.1 -0.2 -1.4 0.1 -0.5 -0.5
Number of children fathered 1.1 1.2 2.0 1.1 1.0 1.3 -1.4 -1.2 -0.5 1.4 0.8 1.0
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 5.9 -1.1 -1.5 -0.5 1.0 1.3 0.7 -2.4 -0.0 -0.7
Age at first live birth 0.7 1.3 5.4 2.3 -0.4 -1.0 0.6 0.7 -0.5 -1.2 -1.3 -0.9
Pulse wave peak to peak time 2.0 2.4 9.1 1.8 0.8 0.1 0.2 0.7 3.0 -0.5 2.7 0.5
Health satisfaction 0.5 0.6 1.3 -0.6 -0.4 -0.8 0.8 0.9 -0.3 -1.1 -1.1 -0.5
Shortness of breath walking on level ground 0.5 0.6 2.3 -0.8 -0.4 -0.9 0.6 0.4 -0.4 -0.2 -1.5 -0.6
Qualifications: College or University degree 0.4 1.2 3.8 1.8 0.6 0.8 -0.8 -0.9 1.9 -0.4 0.7 1.1
Eye problems/disorders: None of the above 0.3 0.4 2.0 1.4 0.7 0.3 -0.2 -0.3 0.2 0.1 0.7 0.1
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.5 1.6 0.5 0.5 -0.6 -0.7 0.3 1.0 0.8 0.7
Emphysema/chronic bronchitis 2.8 3.2 5.3 -0.6 -1.5 -2.1 2.1 2.3 0.0 -2.3 -1.6 -2.0
Medication for pain relief, constipation, heartburn 0.4 0.6 2.5 0.2 -0.4 -0.5 0.8 0.7 1.1 -1.6 -0.1 -0.4
Neck or shoulder pain in last month 0.1 0.1 0.2 0.4 0.2 0.1 0.0 0.4 -0.5 -0.0 -0.3 0.0
Medication: Blood pressure 0.6 1.1 3.3 -0.7 1.8 0.9 -1.2 -1.1 -0.5 1.4 0.1 0.6
Angina (self-reported) 0.4 0.6 1.8 0.4 1.3 0.6 -0.7 -1.0 0.4 0.7 0.7 0.4
Migraine (self-reported) 0.6 0.7 2.0 -0.1 0.6 0.8 -1.0 -0.9 -0.1 1.4 0.7 1.1
Medication: Ibuprofen 1.0 1.2 3.0 1.3 0.6 1.2 -1.3 -1.2 -0.6 1.7 0.5 1.0
Medication: Allopurinol 0.2 0.2 0.8 -0.1 0.2 0.3 0.0 0.6 0.5 0.5 0.9 0.1
Medication: Omeprazole 0.4 0.4 2.5 0.4 0.3 0.4 0.1 0.4 0.2 0.9 1.6 -0.1
Medication: Seretide 50 evohaler 0.2 0.2 1.3 -1.2 -0.3 0.1 0.1 0.1 -0.4 -0.2 0.2 -0.1
Mean time to correctly identify matches 0.2 0.4 1.3 -0.4 0.2 -0.7 1.1 1.1 0.2 -0.1 0.3 -0.7
Heart disease (mother) 1.1 1.4 2.8 0.4 -0.0 1.3 -1.4 -1.6 -1.4 1.7 0.5 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.9 3.4 5.1 1.3 2.1 1.7 -2.2 -1.8 1.1 1.9 1.9 2.2
Whole body fat mass 0.0 0.2 0.6 -0.6 0.3 0.5 -0.4 0.1 0.2 -0.8 -0.1 0.4
Leg fat mass (right) 0.1 0.2 1.0 -1.0 0.1 0.2 -0.0 0.4 0.2 -0.9 -0.2 0.2
Arm predicted mass (right) 0.0 0.2 0.8 -0.0 -0.3 0.1 0.2 0.5 -0.5 -0.6 -0.9 -0.4
Pulse rate, automated reading 0.4 1.3 3.2 -1.8 -0.5 -1.2 1.1 1.0 -1.3 -0.2 -1.2 -1.3
Alcohol intake frequency. 2.2 5.2 10.7 -1.6 -1.8 -2.8 3.0 3.3 -0.9 -1.8 -1.2 -2.8
Comparative height size at age 10 0.1 0.3 0.8 0.5 0.6 0.7 -0.6 -0.4 0.9 -0.5 0.2 0.2
Number of full sisters 1.2 1.5 3.2 -1.2 0.4 1.3 -1.6 -1.8 -0.9 1.4 0.1 1.1
Suffer from ‘nerves’ 1.2 1.9 4.9 -0.8 1.9 0.9 -1.3 -1.7 -1.1 2.2 -0.2 0.9
Overall health rating 0.3 0.7 2.1 -1.4 1.1 -0.7 0.2 -0.2 -1.0 0.6 -0.3 -0.8
Chest pain or discomfort 0.3 0.5 2.1 0.0 0.0 -0.9 0.5 0.3 -0.5 -0.2 -1.4 -1.0
Had major operations 1.2 1.4 4.3 1.2 -0.2 1.4 -0.9 -0.8 -1.1 2.1 0.9 1.1
Age at last live birth 0.2 0.3 1.8 1.3 0.2 -0.4 0.3 0.6 0.1 -0.4 0.2 -0.1
Family relationship satisfaction 5.3 6.6 12.3 -1.8 -1.6 -3.5 3.0 3.0 0.0 -2.7 -2.6 -3.1
Leg pain on walking 1.1 1.3 2.6 0.2 0.9 1.6 -1.3 -1.2 -1.1 1.6 0.1 1.4
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 3.5 0.7 -1.0 -1.7 1.8 1.8 -0.6 -1.1 0.1 -1.9
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.8 0.9 0.7 0.4 -0.4 -0.4 0.2 -0.0 0.1 0.5
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 2.4 1.0 -0.8 -0.9 1.0 0.9 0.8 -1.5 -1.1 -0.5
Medication: Aspirin 0.4 0.5 1.0 -0.9 -0.6 -0.8 0.8 0.7 -0.3 -0.5 -0.6 -1.0
Supplements: Vitamin C 2.7 3.2 6.2 1.7 2.0 2.5 -2.1 -1.9 0.2 1.8 1.1 1.8
Knee pain experienced in last month 0.2 0.4 0.8 -0.9 0.7 0.6 -0.5 -0.2 0.4 0.3 0.8 0.8
Hypertension (Self-reported) 0.3 0.8 2.7 -0.1 1.6 0.9 -0.7 -0.5 -0.8 1.3 0.6 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.9 -0.9 0.7 -0.1 0.2 0.1 0.9 0.5 0.4 0.0
Illnesses of father: Heart disease 0.3 0.4 1.4 1.2 0.6 -0.5 0.7 0.7 -0.3 0.7 0.2 -0.6
Illnesses of siblings: Diabetes 2.6 3.2 5.1 0.2 2.3 1.9 -1.9 -2.1 0.6 2.1 1.7 1.9
Smoking status: Previous 0.4 0.7 1.7 1.2 -0.1 -0.5 0.5 1.1 1.3 -0.6 0.8 0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.4 0.9 0.1 0.9 -1.0 -1.1 -1.2 0.3 0.2 0.2
Whole body fat-free mass 0.0 0.1 0.3 0.3 0.2 0.3 -0.1 0.1 -0.1 -0.3 -0.5 -0.1
Leg fat-free mass (right) 0.0 0.1 0.3 0.4 0.3 0.4 -0.3 -0.2 -0.1 -0.1 -0.6 -0.1
Arm fat percentage (left) 0.1 0.3 0.8 -0.9 0.1 -0.2 0.3 0.7 0.2 -0.9 -0.3 0.0
Average weekly red wine intake 1.3 1.9 3.6 0.4 1.0 1.8 -1.3 -1.1 1.6 0.9 1.6 1.9
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.5 0.1 -0.6 0.2 -0.2 -0.1 -0.1 -0.7 -0.4 0.4
Mood swings 0.1 0.3 1.2 0.7 1.1 -0.1 0.3 0.2 -0.2 0.5 0.3 -0.4
Loneliness, isolation 0.6 0.9 2.7 -1.6 1.6 -0.2 -0.2 -0.2 -1.1 0.9 -0.9 -0.2
Long-standing illness, disability or infirmity 0.3 0.4 1.8 -0.5 0.4 -0.3 0.4 0.6 -1.3 0.7 -0.5 -0.5
Ever had bowel cancer screening 0.5 0.6 1.8 1.3 0.1 -0.5 0.6 0.6 1.2 -0.9 0.5 -0.5
Diabetes diagnosed by doctor 1.0 1.7 7.6 -2.8 -0.6 -1.0 0.9 0.4 -1.3 -0.5 -1.4 -1.3
Ever had stillbirth, spontaneous miscarriage or termination 5.1 5.5 10.8 1.5 1.6 2.8 -2.7 -2.7 -0.4 3.3 2.2 2.5
Friendships satisfaction 1.7 2.1 6.5 0.9 -0.2 -0.9 1.2 1.6 2.4 -2.6 0.8 -0.6
Qualifications: nursing, teaching 0.3 0.4 1.2 1.1 0.1 0.6 -0.6 -0.4 0.9 -0.5 0.6 0.7
Commuting to job workplace: Walk 1.1 1.2 3.7 0.2 -1.5 -1.0 1.5 1.9 -0.5 -0.7 0.2 -1.0
Eye problems/disorders: Cataract 1.9 2.2 4.8 -0.9 -1.9 -1.8 1.4 1.2 -0.5 -1.5 -2.2 -1.2
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 2.2 1.5 0.9 0.9 -1.0 -0.9 -0.0 0.8 1.1 0.7
Medication for cholesterol 1.1 1.7 6.5 -2.5 -0.8 -1.1 0.5 0.2 -1.3 -0.7 -1.9 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.4 -0.0 0.0 -0.2 0.2 0.4 -0.6 -0.4 -0.5 -0.6
Back pain experienced in last month 0.2 0.3 1.4 0.5 -0.8 0.4 -0.0 0.5 -0.0 -1.2 0.2 0.0
Mineral and other dietary supplements 1.2 1.6 6.0 -2.4 -0.3 1.5 -1.1 -1.4 -0.5 1.2 0.6 1.0
Breast cancer (self-reported) 0.3 0.4 1.1 0.7 0.9 -0.1 0.2 -0.2 -0.8 1.0 0.1 -0.4
Asthma (self-reported) 1.2 2.3 4.9 -0.8 -1.1 -1.7 1.5 1.3 -2.1 -0.4 -2.2 -1.7
Osteoporosis (self-reported) 0.6 0.7 4.7 2.2 -0.2 0.0 0.4 0.7 0.7 0.1 0.8 0.3
Osteoarthritis (self-reported) 2.0 2.5 5.5 2.0 2.0 1.3 -1.2 -0.8 0.3 2.3 1.9 1.4
Medication: Aspirin 0.7 0.8 1.4 -0.9 -1.0 -0.9 1.0 0.8 -0.5 -0.8 -1.0 -1.2
Medication: Gliclazide 1.3 1.4 3.3 0.3 -1.5 -1.4 1.4 1.4 0.1 -1.8 -0.7 -1.0
Illnesses of father: None of the above (group 1) 1.7 2.1 3.8 -0.8 -1.7 -1.7 1.5 1.2 -0.5 -2.0 -1.7 -1.4
Smoking status: Current 1.2 1.9 3.7 -1.6 0.8 1.6 -1.8 -1.6 0.2 1.1 0.9 1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 4.3 -1.4 -2.1 -1.5 1.9 1.4 -0.3 -1.6 -0.6 -1.8
Whole body water mass 0.0 0.1 0.3 0.4 0.1 0.3 -0.0 0.1 -0.1 -0.3 -0.5 -0.2
Leg predicted mass (right) 0.0 0.1 0.4 0.4 0.3 0.3 -0.2 -0.2 -0.2 -0.1 -0.6 -0.1
Arm fat mass (left) 0.1 0.2 1.0 -0.5 -0.1 -0.0 0.3 0.6 0.0 -1.0 -0.4 -0.1
Number of self-reported non-cancer illnesses 0.2 0.3 1.1 -0.4 0.2 -0.4 0.5 0.6 -1.1 1.0 -0.1 -0.3
Average weekly champagne plus white wine intake 0.3 0.4 1.2 0.3 0.2 1.1 -0.8 -0.8 0.2 0.4 0.3 0.8
Miserableness 0.3 0.4 1.3 -0.8 1.2 0.4 -0.4 -0.2 1.0 -0.2 0.7 0.5
Guilty feelings 0.3 0.4 2.2 -0.5 1.5 0.6 -0.6 -0.2 0.2 0.1 0.3 0.8
Wears glasses or contact lenses 0.2 0.2 1.2 0.5 0.4 0.2 -0.1 -0.1 1.1 -0.2 0.4 0.3
Ever taken oral contraceptive pill 1.8 2.0 7.5 2.7 0.8 1.3 -1.6 -1.2 -0.1 1.0 0.8 1.5
Hearing aid user 0.1 0.1 0.4 -0.2 0.4 0.0 -0.2 0.1 0.2 -0.1 -0.6 0.2
Mother’s age at death 1.5 1.8 5.7 1.5 0.9 1.1 -0.7 -0.5 2.4 -0.6 2.2 0.9
Financial situation satisfaction 2.4 2.9 6.2 1.0 -1.3 -2.0 2.3 2.5 0.4 -2.1 -0.4 -1.8
Tinnitus: Yes, now most or all of the time 0.2 0.3 0.5 0.5 0.7 0.2 -0.6 -0.0 0.5 0.7 -0.2 0.7
Commuting to job workplace: Public transport 0.3 0.4 0.7 -0.5 -0.8 -0.3 0.6 0.8 0.7 -0.8 0.1 -0.3
Eye problems/disorders: Glaucoma 0.8 1.0 3.3 -0.0 1.1 0.7 -0.8 -0.3 1.5 0.2 1.8 0.9
Medication: Blood pressure 0.5 0.9 2.3 1.2 1.1 0.6 -0.0 0.4 1.5 0.4 1.3 0.6
Pain type(s) experienced in last month: Hip pain 0.6 0.8 2.5 1.6 -0.0 -0.3 0.7 1.1 0.7 -1.4 0.0 -0.6
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.5 1.2 0.6 -0.9 0.7 0.9 1.0 -0.7 -0.4 -0.5
High cholesterol (Self-reported) 0.3 0.5 1.8 1.2 0.2 0.2 -0.1 0.2 -0.0 1.3 0.8 0.6
Medication: Bendroflumethiazide 0.2 0.3 1.5 0.3 0.4 0.0 0.1 0.3 1.2 -0.7 0.2 0.1
Medication: Paracetamol 1.2 1.8 4.7 1.3 0.9 1.3 -1.5 -1.2 -0.9 2.2 0.5 1.5
Medication: Lisinopril 0.5 0.6 2.6 -1.6 1.4 0.4 -0.4 -0.5 0.0 0.8 0.2 0.2
Medication: Atorvastatin 0.8 1.0 2.8 0.2 0.8 1.0 -1.2 -1.7 -1.0 1.1 -0.3 0.7
Illnesses of father: High blood pressure 1.0 1.2 2.8 1.2 1.0 1.2 -0.9 -0.5 1.7 -0.0 1.5 1.1
Alcohol drinker status: Never 0.2 0.2 1.1 1.0 0.7 -0.2 -0.1 0.0 0.3 -0.2 -0.0 -0.2
Ever smoked 0.1 0.1 0.4 0.1 0.0 -0.1 -0.1 0.3 0.5 -0.6 -0.3 0.6
Basal metabolic rate 0.0 0.1 0.3 0.2 0.2 0.4 -0.2 0.0 0.1 -0.5 -0.4 0.0
Leg fat percentage (left) 0.1 0.4 1.9 -1.4 0.0 -0.3 0.3 0.8 0.5 -0.9 -0.3 0.3
Arm fat-free mass (left) 0.0 0.1 0.3 0.2 -0.1 0.3 0.1 0.4 -0.1 -0.5 -0.5 -0.3
Number of operations (self-reported) 1.5 2.2 6.1 1.7 0.4 1.7 -1.2 -1.0 -0.7 2.5 1.6 1.5
Average weekly beer plus cider intake 1.3 1.9 5.0 -2.2 -1.3 -1.4 1.1 0.8 -0.8 -1.4 -1.7 -1.1
Irritability 0.3 0.5 2.4 -1.6 0.7 -0.1 0.4 0.6 0.3 -0.1 1.0 -0.7
Risk taking 5.5 8.0 13.0 0.9 3.1 3.4 -3.6 -3.2 0.9 3.2 2.2 3.2
Ever had prostate specific antigen (PSA) test 0.9 1.0 1.9 0.8 1.3 0.9 -1.0 -0.7 0.6 1.1 1.4 1.0
Fractured/broken bones in last 5 years 1.4 1.8 4.0 -1.3 -1.4 -1.3 1.4 1.6 -0.5 -0.9 -2.0 -1.2
Age started oral contraceptive pill 0.1 0.1 0.3 0.0 0.6 0.2 0.0 -0.4 -0.1 0.3 -0.4 -0.2
Diastolic blood pressure, automated reading 1.2 3.7 7.7 1.4 1.8 2.8 -2.1 -1.5 1.1 1.8 2.0 2.3
Ever depressed for a whole week 1.1 1.4 3.5 -0.3 1.2 0.8 -1.3 -1.8 -0.7 1.9 -0.8 0.7
Unable to work because of sickness or disability 1.2 1.5 7.0 -2.7 -0.8 -1.0 0.7 1.1 0.9 -1.4 -0.1 -0.5
Commuting to job workplace: Cycle 1.3 1.6 3.2 1.6 1.8 1.0 -1.0 -0.9 1.2 1.1 1.2 1.3
Myopia 0.3 0.5 1.2 -0.7 -0.2 -0.6 0.9 0.8 -0.1 -1.1 -0.2 -0.8
Vascular/heart problems diagnosed by doctor 0.3 0.8 2.9 -0.1 -1.7 -0.9 0.8 0.6 0.6 -1.3 -0.7 -0.5
Cholesterol lowering medication 0.3 0.4 2.2 0.9 -0.3 0.3 -0.0 0.2 0.3 0.5 1.5 0.4
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.8 0.6 0.8 0.5 -0.2 0.1 0.5 1.1 1.4 0.2
Pain experienced in last month 0.6 0.9 2.0 -0.3 1.3 0.5 -0.9 -1.2 0.9 1.4 0.5 1.0
Supplements: Calcium 0.2 0.2 0.5 0.3 -0.7 -0.4 0.4 0.5 -0.6 0.1 -0.3 -0.6
Basal cell carcinoma (self-reported) 0.4 0.5 2.2 0.3 -0.5 0.1 -0.1 -0.3 -1.5 0.4 -1.2 -0.2
Heart attack/myocardial infarction (self-reported) 2.0 2.5 4.0 -1.2 1.5 1.8 -2.0 -1.7 -0.2 1.8 1.2 2.0
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.2 -0.2 1.1 0.1 -0.2 -0.1 -0.9 1.0 -0.2 -0.3
Heart disease (siblings) 0.2 0.2 0.4 0.3 -0.3 0.7 -0.4 -0.5 -0.7 0.6 0.2 0.2
Alcohol drinker status: Previous 0.3 0.3 1.1 -0.5 -0.1 -0.4 1.0 1.0 -0.2 -0.0 0.1 -0.6
Pack years of smoking 0.3 0.4 1.4 -0.2 -0.4 -0.6 1.1 1.2 0.2 0.1 -0.3 -0.6
Impedance of whole body 0.5 2.6 4.3 0.3 1.0 1.8 -1.9 -1.6 2.1 0.4 2.0 2.0
Leg fat mass (left) 0.1 0.3 1.0 -1.0 -0.0 0.0 0.1 0.5 0.2 -0.9 -0.3 0.1
Arm predicted mass (left) 0.0 0.1 0.3 0.2 0.1 0.4 0.0 0.3 -0.1 -0.5 -0.5 -0.1