Hub : Genes

AGTRAP

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0740 0.0300 2.3e-03 0.053 0.021 0.070 0.047 0.064 4.7e-07 1.2e-03 7.4e-09 2.0e-06 3.3e-08
2 GTEx Artery Aorta 0.1320 0.0580 7.1e-03 -0.001 NA -0.005 NA 0.000 3.7e-01 NA 7.5e-01 NA 3.2e-01
3 GTEx Esophagus Mucosa 0.2030 0.0690 4.5e-03 0.154 NA 0.191 NA 0.178 1.7e-10 NA 8.3e-13 NA 5.3e-12
4 GTEx Liver 0.4270 0.1430 5.2e-03 0.020 NA -0.006 NA 0.009 9.2e-02 NA 5.0e-01 NA 1.7e-01
5 GTEx Skin Sun Exposed Lower leg 0.0960 0.0390 4.5e-03 0.016 NA 0.049 NA 0.049 1.6e-02 NA 6.6e-05 NA 6.7e-05
6 GTEx Thyroid 0.2170 0.0680 1.6e-03 0.183 NA 0.125 NA 0.177 6.0e-14 NA 8.6e-10 NA 1.6e-13
7 METSIM Adipose 0.0395 0.0183 7.7e-03 0.045 0.004 0.009 0.015 0.028 2.7e-07 6.6e-02 1.5e-02 2.2e-03 3.8e-05
8 NTR Blood 0.0152 0.0076 2.1e-02 0.000 0.002 0.000 0.002 0.001 3.2e-01 7.0e-02 2.2e-01 5.2e-02 1.5e-01
9 YFS Blood 0.2864 0.0377 0.0e+00 0.107 0.116 0.154 0.152 0.147 3.5e-33 7.5e-36 4.1e-48 2.2e-47 1.1e-45
10 TCGA Bladder Urothelial Carcinoma 0.0690 0.0320 8.0e-03 0.041 0.031 0.029 NA 0.032 2.2e-04 1.1e-03 1.5e-03 NA 9.0e-04
11 TCGA Cervical Squamous Cell Carcinoma 0.1010 0.0480 7.4e-03 0.062 0.037 0.029 NA 0.019 5.1e-04 6.3e-03 1.4e-02 NA 3.7e-02
12 TCGA Kidney Renal Clear Cell Carcinoma 0.0426 0.0218 3.0e-03 0.024 0.024 0.001 NA 0.019 8.9e-04 8.0e-04 2.3e-01 NA 2.7e-03
13 TCGA Lung Adenocarcinoma 0.0579 0.0280 1.7e-03 0.001 0.018 0.013 NA 0.015 2.2e-01 3.2e-03 1.0e-02 NA 5.9e-03
14 TCGA Lung Squamous Cell Carcinoma 0.0741 0.0301 3.5e-04 0.049 0.048 0.036 NA 0.037 2.5e-06 3.7e-06 5.6e-05 NA 3.9e-05
15 TCGA Testicular Germ Cell Tumors 0.2390 0.0900 4.5e-03 0.101 0.063 0.028 NA 0.059 2.0e-04 2.9e-03 3.6e-02 NA 3.8e-03
16 TCGA Thyroid Carcinoma 0.1770 0.0430 5.2e-14 0.169 0.150 0.158 NA 0.169 3.1e-16 1.8e-14 3.2e-15 NA 2.9e-16

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bipolar Disorder (2018) 0.7 1.1 5.3 -0.0 0.0 -0.6 -1.4 0.1 -1.0 1.4 1.7 1.0 0.0 0.4 -2.3 0.3 1.2 1.0 -1.1
Bipolar Disorder or Schizophrenia 1.1 2.6 16.3 -0.9 -0.8 0.8 -0.5 -0.1 -1.4 0.4 4.0 0.2 1.6 1.2 -2.8 0.1 2.0 2.2 -0.4
Depressed Affect (Nagel 2018) 0.4 0.9 3.6 -0.3 0.2 1.9 0.1 0.6 0.9 1.1 -0.4 0.9 -0.5 0.8 1.2 -0.0 1.5 -1.2 1.1
Depression (Nagel 2018) 0.5 0.8 3.2 -1.8 1.2 0.7 -0.2 0.6 -0.2 0.4 -1.5 0.1 0.7 -0.0 0.4 1.3 1.3 0.6 0.1
Intelligence (Savage-Jansen 2018) 0.6 2.0 6.9 0.8 -2.4 -0.3 0.5 -1.0 1.4 -0.6 1.5 0.2 -2.6 -0.9 -0.8 -1.7 -2.2 -1.7 0.3
Neuroticism (Nagel 2018) 1.0 2.4 7.3 0.3 0.8 2.7 0.3 1.3 1.9 0.2 0.7 2.4 0.3 2.1 1.4 0.5 2.7 -1.1 1.9
Schizophrenia (2018) 0.9 2.0 14.6 -1.1 -0.2 1.4 0.5 -0.1 -1.0 -0.4 3.8 -0.9 1.1 1.0 -1.9 -0.3 1.4 1.9 0.3
Schizophrenia vs Biploar Disorder 1.1 1.5 5.6 0.0 0.0 -1.3 0.3 -1.9 0.0 -1.4 -0.6 -1.8 0.0 -1.8 -0.2 -2.4 -1.9 0.4 -0.2
Worry (Nagel 2018) 1.4 3.0 7.7 0.9 1.7 2.1 0.7 0.7 2.2 -1.0 1.1 2.8 1.6 2.3 2.1 0.9 2.6 -0.8 1.9
Alzheimer’s Disease (in mother) 0.4 0.5 2.6 -0.5 -0.1 1.3 0.8 0.6 0.1 -1.6 -0.1 -0.1 0.1 0.7 0.2 0.2 1.0 0.3 0.9
Alzheimer’s Disease (in father) 5.1 5.5 13.0 -1.6 -1.5 -3.4 -1.1 -3.6 -1.8 -2.2 -0.3 -2.0 -1.1 -3.0 -3.3 -2.9 -3.0 1.1 -2.3
Alzheimer’s Disease (including proxy) 1.7 2.5 7.8 -2.0 -0.3 -1.1 -0.5 -2.4 -2.0 -2.8 -0.7 -1.9 0.1 -1.4 -1.8 -1.7 -0.8 1.8 -0.9
Crohns Disease (2017) 0.2 0.4 1.8 0.3 -0.7 -0.9 -0.4 -0.2 -0.3 0.1 -0.5 0.1 -0.2 -0.5 -1.4 -0.4 -0.0 0.2 -1.1
Irritable Bowel Disease (IBD) 0.6 1.3 2.8 -0.3 -1.6 -1.7 -0.3 -0.5 -0.9 1.1 -0.7 -1.1 -1.5 -1.6 -1.6 -1.3 -1.3 0.1 -1.3
Ulcerative Colitis (UC) 0.8 1.5 3.5 -0.5 -1.2 -1.9 -0.1 -0.6 -1.1 1.5 -0.7 -1.6 -1.5 -1.6 -1.0 -0.9 -1.8 0.4 -1.1
Major Depression (MDD) 1.0 1.2 6.0 -0.3 -1.8 0.0 -2.3 -2.5 0.0 -1.2 -0.5 -1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.3 0.5 1.5 0.2 -0.2 0.7 -0.5 1.1 0.5 1.0 1.1 1.0 0.5 -0.3 -0.0 0.5 0.2 -1.2 -0.7
Verbal and Numeric Reasoning (VNR) 0.5 1.2 3.8 0.3 -1.4 -0.3 -0.8 -2.0 0.2 -0.2 -0.2 -0.7 -1.7 -1.2 -0.3 -1.9 -1.9 -0.6 0.3
Breast Cancer 0.7 1.7 7.0 0.3 -2.2 0.3 1.6 1.4 0.4 1.0 -0.1 0.9 -1.4 -1.0 -2.6 -2.2 -0.6 -0.9 -0.2
Ovarian Cancer 0.8 1.0 3.7 1.5 -0.6 -0.3 -0.1 0.2 1.8 0.3 0.4 1.7 -0.8 1.1 0.4 1.2 0.2 -1.9 0.7
Prostate Cancer 0.9 1.2 4.0 -0.8 -0.2 -0.8 -1.4 -1.9 -1.0 0.2 1.2 0.5 1.2 -0.7 -2.0 -0.8 0.4 1.2 -1.3
Age at First Birth 0.4 0.5 1.7 -0.2 0.2 -0.1 -0.1 -0.2 -0.1 1.2 0.2 1.2 1.3 0.7 -0.9 0.7 1.0 0.3 -1.0
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 2.4 -0.4 0.0 -0.4 -0.6 0.1 -0.7 0.5 -1.6 -0.5 0.0 -0.7 0.2 -0.9 -0.7 0.3 0.0
Coronary Artery Disease (CAD) 0.4 0.5 1.8 0.0 0.0 -0.2 -0.9 -0.2 -0.7 1.2 -0.6 0.2 0.0 -1.3 -0.8 -0.3 -0.6 0.8 -1.1
Crohns Disease (2012) 0.2 0.3 0.8 0.0 0.0 -0.3 -0.6 -0.4 0.8 0.2 -0.6 0.5 0.0 0.9 -0.2 0.1 0.9 0.2 0.8
Mean Putamen Volume 0.6 0.6 2.4 -0.6 0.1 0.3 1.3 0.7 0.2 0.8 -0.2 0.3 -0.1 1.6 0.9 0.6 0.9 -1.1 1.1
Fasting Glucose 0.6 0.7 3.5 -0.4 0.1 -0.3 0.4 -0.6 -0.6 -0.7 -1.9 -0.7 -0.9 -1.1 0.4 -1.0 -1.4 0.2 -0.5
HbA1C 1.3 1.5 6.0 -1.3 1.0 1.6 0.7 2.4 -0.8 -0.8 -0.2 -1.1 0.9 1.4 0.7 1.7 0.4 0.7 1.6
HDL Cholesterol 0.3 0.5 1.3 -0.6 0.1 -1.1 -0.4 -0.9 -0.2 -1.0 -0.1 -0.8 0.2 -1.1 -0.1 -1.0 -1.0 -0.5 -0.3
LDL Cholesterol 0.3 0.4 2.4 0.5 1.0 -0.7 0.5 -0.7 -0.3 -0.2 -1.5 -0.4 0.3 0.1 0.9 0.6 -0.1 0.4 -0.1
Lupus 0.8 1.2 6.6 -0.2 -1.8 0.4 0.3 1.4 0.9 0.6 2.6 1.2 -0.4 0.8 -1.8 -0.9 0.3 -0.1 0.4
Neuroticism (2016) 1.0 1.5 13.5 0.5 -0.8 -0.6 -1.9 -1.2 -0.3 -3.7 0.4 -1.2 -0.6 -0.8 0.3 0.3 -1.0 -0.3 0.1
Primary Biliary Cirrhosis 0.6 0.8 3.5 0.3 -1.7 -0.2 -0.8 1.4 0.3 -0.2 -1.0 0.4 -1.9 0.2 -0.8 -0.4 -0.7 -1.2 0.1
Rheumatoid Arthritis 0.6 0.8 4.9 2.2 0.0 0.2 1.1 1.0 1.4 -0.0 0.2 1.2 0.0 0.2 0.7 0.1 -0.1 -1.2 0.2
Schizophrenia (2014) 0.7 1.5 4.9 -1.0 0.1 -0.4 -0.5 -1.2 -1.9 -0.5 2.1 -1.3 1.0 0.0 -1.7 0.4 0.7 2.2 -1.0
Triglycerides 0.4 0.7 2.3 1.5 -1.0 -0.6 0.8 -0.8 1.1 -1.1 0.0 0.8 -1.5 0.5 -0.3 -0.9 -0.3 -0.5 0.4
Type 2 Diabetes (T2D) (2012) 0.6 0.7 3.1 -0.5 0.0 -1.5 -1.8 -1.2 -0.6 0.1 1.3 0.1 0.0 0.0 -1.2 0.0 -0.1 0.1 -0.4
Ulcerative Colitis 0.3 0.4 1.3 -0.6 -0.6 -0.7 0.7 -0.2 -0.1 1.1 -0.9 -0.8 -1.1 -0.3 0.2 -0.3 -0.8 0.0 0.3
Blood Eosinophil Count 0.3 2.0 11.4 1.5 0.7 -0.1 1.6 0.3 -1.6 0.8 0.6 0.0 1.9 -0.4 -1.7 -1.0 1.4 3.4 -1.3
Blood Platelet Count 0.4 4.6 22.8 -1.3 -0.5 -0.5 0.5 2.5 -1.8 0.7 -4.8 0.5 1.5 -0.1 -3.9 0.8 0.0 3.9 -2.1
Blood Red Count 0.2 2.3 9.1 -2.2 2.1 1.5 2.4 0.0 -1.5 -0.6 -2.0 -1.6 0.1 -0.7 3.0 -0.5 0.3 -0.2 0.4
Blood White Count 0.4 2.7 16.5 -4.1 1.3 0.9 0.1 0.5 -3.1 0.0 -0.1 -1.5 1.0 -1.2 -0.6 -0.3 1.1 2.1 -2.0
Heel T-Score 0.1 1.2 5.7 -0.6 1.4 0.6 2.4 0.6 0.1 0.2 1.1 0.4 1.3 0.8 1.8 1.7 0.4 0.2 0.3
BMI 0.5 2.9 11.7 -1.5 0.5 -2.0 -3.4 -1.5 -1.5 -1.3 -2.9 -1.3 -0.8 -2.1 0.1 -1.6 -1.1 -0.5 -1.7
Height 0.1 1.6 6.9 2.6 -0.9 0.3 -1.1 1.3 1.8 0.5 -2.4 1.2 -1.1 0.7 0.7 0.2 -0.4 -1.1 0.9
Waist Hip Ratio (WHR) 0.3 1.4 4.2 0.5 -2.0 -1.5 -0.9 -0.7 -0.8 0.5 2.0 -0.4 -0.9 -1.1 -1.6 -0.3 -0.8 -1.1 -1.6
Systolic Blood Pressure 3.4 17.2 118.8 -0.1 -4.1 -0.8 -0.7 2.9 0.8 1.3 10.9 4.7 2.6 3.0 -6.5 -1.0 5.2 4.4 0.5
Smoking Status 0.3 0.8 2.3 -1.0 0.6 0.8 -1.2 -1.3 -0.9 -0.0 1.5 0.8 0.9 -0.5 -1.0 -0.3 0.7 0.4 -1.2
Allergy or Eczema 0.6 1.5 8.5 2.5 -1.5 -0.7 -0.5 -1.2 -0.2 -0.3 2.9 -0.7 -0.5 -0.3 -1.3 -1.1 -0.0 0.5 -0.3
Cardiovascular Disease 2.0 6.7 49.0 0.1 -4.5 -0.9 -2.1 0.8 0.5 -1.4 7.0 1.5 -1.3 0.6 -4.5 -1.7 1.4 1.0 -0.2
Hypothyroidism (self reported) 0.3 0.6 2.4 1.4 -0.3 -0.4 0.3 -1.5 -0.0 -0.9 0.6 -0.2 -0.9 -1.0 -0.5 -1.1 -0.8 0.1 -0.6
Respiratory disease 0.6 1.4 5.0 1.9 -1.3 -0.7 -0.4 -2.2 0.7 -0.0 2.2 1.1 -0.7 -0.5 -0.8 -1.0 -0.4 -1.4 -0.8
Type 2 Diabetes (T2D) (2018) 0.6 1.1 3.9 0.9 -2.0 -0.8 -0.5 -0.4 0.9 -0.1 0.2 1.8 -1.2 -0.6 -1.6 -1.1 -0.2 -1.1 -1.0
Lung FEV1/FVC ratio 0.2 1.1 4.8 -1.5 -0.5 -0.6 0.6 -1.4 -0.9 -1.4 -0.6 -1.6 0.2 -0.8 -0.5 -1.1 -0.1 2.2 0.5
Lung FVC 0.1 0.6 2.7 -1.4 1.0 -0.3 -0.8 -0.2 -0.8 -0.1 -1.1 -1.7 0.3 -0.1 -0.2 0.2 -1.0 -0.2 -0.3
Neuroticism 0.6 1.4 4.4 0.0 0.6 2.0 0.7 1.6 1.2 -0.3 0.7 1.6 0.3 1.6 1.1 0.5 2.1 -0.3 1.4
Chronotype (morning person) 0.2 0.5 3.1 1.8 1.0 -0.6 0.7 -0.1 1.1 0.1 -0.8 1.0 0.3 0.0 0.2 0.2 0.0 0.4 -0.1
Hair Pigment 0.1 1.9 8.4 -0.5 -1.1 -0.7 -1.0 -1.5 -1.5 -1.6 -2.9 -2.6 -0.4 -0.6 -0.9 -1.5 -0.5 0.7 0.3
Tanning 0.1 1.1 6.8 2.6 -0.6 -0.0 -1.1 0.7 1.1 0.9 0.3 1.2 0.7 -0.1 -1.4 -0.8 1.3 1.1 -0.1
Hand grip strength (left) 0.3 0.9 2.7 -1.5 1.5 0.7 -0.3 0.5 -1.2 1.6 0.0 -0.7 1.5 0.2 0.0 1.0 0.4 0.6 -0.3
Number of treatments/medications taken 1.3 2.4 7.7 1.5 -2.7 -0.8 -1.6 -1.2 1.1 0.2 2.8 2.0 -1.5 -1.0 -1.9 -1.6 -0.1 -0.8 -0.8
Average weekly spirits intake 0.6 0.7 2.0 -1.4 0.6 0.7 -0.8 0.5 -1.2 1.0 1.4 -0.5 0.8 0.7 0.5 1.0 1.0 -0.2 0.1
Sensitivity / hurt feelings 0.2 0.3 1.3 0.8 -0.6 0.1 -0.1 0.4 0.3 -0.7 0.0 0.3 -0.6 0.2 -1.2 -0.8 0.2 0.8 0.6
Frequency of depressed mood in last 2 weeks 0.4 0.6 5.6 -0.9 0.1 -0.3 -2.4 -1.2 -0.5 -0.4 -0.2 -0.4 0.2 -0.2 -0.2 0.3 0.8 0.6 -0.2
Hearing difficulty/problems: Yes 0.5 0.7 3.9 -0.6 -0.3 0.0 -0.2 -0.8 -0.8 -1.4 -1.0 -2.0 -0.6 -0.5 -0.0 -0.4 -0.6 1.3 0.6
Relative age of first facial hair 1.2 2.5 11.3 -0.8 0.9 1.9 1.0 0.9 0.0 -0.7 0.3 -0.1 1.1 3.4 1.3 1.1 2.0 1.7 3.1
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.8 -0.8 0.6 0.6 -0.7 0.6 -0.3 -0.0 1.7 0.2 -0.2 -0.1 1.1 0.8 0.3 -0.6 -0.1
Ever used hormone-replacement therapy (HRT) 1.0 1.3 7.2 0.5 0.2 2.0 2.0 2.7 0.7 0.6 -0.6 1.2 0.5 0.3 0.1 0.7 0.7 -0.7 0.0
Ever had hysterectomy (womb removed) 0.8 0.9 8.2 -0.4 0.3 0.1 1.1 1.4 -0.3 0.6 -2.9 -0.5 0.1 -0.8 0.1 0.8 -0.7 -0.0 -0.7
Systolic blood pressure, automated reading 2.1 6.1 33.8 0.7 -3.3 -1.6 0.3 2.1 0.4 -0.7 5.8 2.5 0.9 1.6 -4.4 -1.4 2.4 2.7 1.0
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.2 0.7 -0.6 -0.1 0.5 0.5 0.8 0.1 -0.3 0.0 -1.0 -0.8 -0.1 0.4 -1.5 -0.8 -0.4
Angina 0.5 0.6 3.0 -1.0 0.9 -0.5 -0.9 -1.3 -0.6 0.4 -0.2 -0.1 1.7 -0.5 0.7 0.2 0.7 0.4 -0.7
Medication for hormone replacement therapy 0.8 0.9 2.7 0.3 0.7 0.3 1.0 0.9 -0.7 0.5 -1.6 -0.4 0.9 -0.7 0.3 1.5 -0.3 -1.2 -1.6
Vitamin and mineral supplements 1.3 1.7 4.9 1.9 -1.3 -2.2 -1.7 -1.7 -0.6 -0.8 -2.0 -0.8 -1.1 -0.2 -0.9 -1.3 -1.4 0.2 0.6
Supplements: Zinc 1.1 1.2 4.5 -1.3 -0.2 -0.3 0.7 -0.1 -1.5 0.6 -1.0 -1.8 -0.9 -2.1 0.0 -0.1 -1.3 -0.5 -1.6
Medication: Co-codamol 0.4 0.5 1.6 -1.3 0.8 1.0 0.4 0.4 0.0 0.8 0.0 -0.4 0.4 0.0 0.9 1.1 0.6 0.4 0.2
Medication: Metformin 1.7 2.5 5.1 1.9 -2.2 -2.3 -1.0 -0.8 1.0 1.1 0.0 1.0 -2.0 -2.1 -1.5 -1.1 -1.9 -1.5 -1.8
Diabetes (father) 0.8 1.0 4.0 -1.2 0.1 -1.0 -0.2 -2.0 -1.4 0.5 -0.7 -0.9 0.3 -0.9 -1.5 -0.9 -0.4 1.2 -0.7
Diabetes (mother) 0.7 0.8 3.4 0.1 1.0 0.3 1.2 0.2 -0.1 0.2 1.1 0.7 1.8 0.5 -0.4 0.8 1.4 1.5 -0.5
Severe depression (siblings) 1.0 1.1 3.3 1.3 0.8 0.7 0.2 -0.1 1.8 -0.2 0.7 1.8 0.8 0.8 1.6 0.8 0.7 -1.5 0.5
Pack years adult smoking proportion 0.9 1.4 6.1 -2.2 0.6 -0.4 0.5 -0.2 -0.4 -0.1 -2.0 -0.1 0.4 -2.2 -0.9 -0.7 -0.8 -0.2 -2.5
Impedance of leg (right) 0.3 1.2 4.3 2.1 0.2 0.6 1.9 1.6 1.7 0.8 0.1 1.3 0.1 -0.1 0.8 1.1 -0.6 -1.1 -0.2
Leg fat-free mass (left) 0.3 1.6 8.9 -1.0 -0.5 -0.9 -3.0 -1.6 -1.5 -0.8 -1.9 -1.5 -0.8 -0.6 -0.7 -1.7 -0.1 0.4 -0.3
Trunk fat percentage 0.3 1.3 4.5 -0.5 0.2 -0.9 -1.1 -1.0 -1.0 -1.5 -2.1 -1.1 -1.1 -1.9 0.3 -1.6 -0.8 -0.1 -1.0
Hand grip strength (right) 0.1 0.3 1.1 -0.8 0.7 -0.4 -0.1 0.1 -0.8 0.5 -0.7 -0.7 0.4 -0.1 -0.5 0.2 -0.5 1.0 -0.2
Townsend deprivation index at recruitment 0.9 1.2 7.5 0.2 -1.2 0.9 -1.2 -0.8 0.1 0.3 2.7 1.3 0.6 0.8 -1.6 -0.6 1.3 0.4 0.4
Current tobacco smoking 0.6 1.0 5.8 -1.0 0.9 1.4 -0.3 -1.5 -0.1 -0.2 2.4 1.1 1.4 0.4 -0.1 0.1 1.1 -0.1 -0.0
Average weekly fortified wine intake 0.8 1.0 3.1 -0.0 0.4 1.1 0.4 0.2 0.9 1.8 1.2 1.1 0.9 1.0 0.2 1.7 1.4 -0.8 -0.2
Maternal smoking around birth 1.0 1.5 6.4 1.5 -0.4 1.1 0.9 0.6 1.7 0.4 0.1 2.5 -0.5 1.6 0.9 0.7 1.4 -1.9 0.8
Fed-up feelings 0.3 0.6 5.1 -0.2 -0.0 0.5 -2.2 -0.9 0.0 -0.2 0.3 0.3 0.6 0.9 -0.5 0.2 1.2 0.1 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 2.0 11.2 -3.4 1.7 1.3 -0.4 0.7 -1.8 0.4 -0.8 -1.1 1.8 -0.4 0.2 1.4 1.5 1.4 -0.5
Relative age voice broke 1.8 2.7 10.9 -1.2 0.9 1.8 0.6 1.6 0.2 -1.4 0.1 -0.1 0.6 3.3 1.3 2.3 1.4 1.6 3.3
Taking other prescription medications 1.2 1.8 4.2 2.0 -1.9 -1.1 -0.6 -2.0 1.5 -0.2 1.3 1.8 -2.0 -1.1 -0.5 -1.0 -1.2 -1.2 -0.5
Age when periods started (menarche) 0.6 1.5 5.0 2.0 -2.2 -0.2 0.0 0.9 2.0 1.8 0.8 1.4 -0.8 1.1 -1.3 -0.0 0.6 -0.6 0.8
Bilateral oophorectomy (both ovaries removed) 0.7 0.9 5.2 1.6 0.1 -0.3 0.1 0.8 1.8 0.1 -0.4 2.3 0.6 0.5 0.0 0.6 -0.3 -0.8 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 5.6 0.7 0.5 -2.0 -1.1 -1.1 -0.1 -2.4 -0.4 0.1 0.1 0.2 0.2 -0.4 -1.1 -0.4 -0.3
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 2.2 1.5 -0.8 0.4 0.2 -0.0 0.4 -0.1 0.1 0.4 -1.2 -0.3 0.5 -0.9 -0.6 -1.3 0.1
Qualifications: CSEs or equivalent 0.5 0.6 4.3 -0.9 0.1 -0.7 -0.2 0.1 -0.9 0.4 -2.1 -0.6 0.0 -0.2 -1.2 -0.5 0.2 0.9 -0.6
Serious illness, injury or assault to yourself 0.3 0.4 1.6 -0.8 -0.4 0.0 -0.7 0.4 -0.5 1.3 -0.1 -0.9 -0.4 -0.4 -0.7 -0.4 -0.5 0.5 -0.1
High blood pressure 1.7 4.7 34.3 0.3 -3.6 -0.5 -1.3 0.7 0.5 -1.2 5.9 1.7 -0.8 0.8 -3.3 -1.6 1.9 1.1 0.5
Hayfever, allergic rhinitis or eczema 0.4 0.9 2.8 1.6 -1.2 -0.8 -0.2 -0.7 -0.4 -0.4 1.7 -0.6 -0.8 -1.0 -1.2 -0.9 -0.4 0.0 -1.0
Multivitamins +/- minerals 1.4 1.8 6.9 -1.7 0.5 2.6 2.2 2.2 0.3 0.1 1.4 0.7 1.0 0.4 -0.1 0.9 1.9 0.1 -0.3
Stomach or abdominal pain in last month 0.3 0.4 1.6 -0.1 -1.2 -0.2 -0.8 -1.3 -0.0 -0.5 0.8 -0.1 -0.6 0.0 -0.6 -0.2 -0.0 -0.6 -0.2
Supplements: Glucosamine 0.9 1.2 7.8 -0.5 -0.5 0.4 -0.8 1.2 0.4 2.8 1.6 1.3 0.5 -0.1 -0.6 1.0 1.2 -0.6 -1.0
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 4.3 -1.0 0.3 1.4 2.1 0.9 0.5 0.1 0.0 0.5 0.1 0.7 0.9 0.0 0.1 -0.8 0.9
Medication: Atenolol 0.8 1.0 4.9 0.3 -1.1 0.3 -1.4 -0.3 0.3 0.6 2.2 1.1 0.3 1.4 -0.6 0.1 1.6 -0.1 1.2
Medication: Levothyroxine sodium 0.6 1.0 5.7 -0.0 0.0 -1.5 -0.4 -2.4 -0.9 -1.4 -0.6 -0.7 -0.2 -1.1 -0.5 0.0 -0.8 -0.3 -1.3
Sitting height 0.1 0.7 7.0 1.1 -0.1 -0.3 0.2 -0.3 0.6 0.7 -2.6 0.1 -0.5 -0.2 -0.2 -0.5 -0.9 -0.6 -0.2
Chronic bronchitis/emphysema (father) 0.4 0.4 1.8 1.4 -0.4 -0.5 -1.0 -0.5 0.5 -1.2 -0.0 -0.0 -1.1 -0.4 0.4 -0.3 -0.6 -0.3 0.2
High blood pressure (mother) 1.5 2.1 8.2 -0.8 -0.1 0.6 -0.7 0.8 0.2 1.4 2.9 1.4 1.7 1.9 -1.5 0.9 2.7 1.5 0.4
Body mass index (BMI) 0.5 2.1 5.8 -1.9 0.9 -1.1 -2.4 -1.4 -2.0 -1.4 -2.3 -1.6 -0.0 -1.7 -0.0 -1.3 -0.1 0.8 -1.4
Impedance of leg (left) 0.1 0.6 2.9 0.9 0.6 0.3 1.7 1.1 0.6 0.3 0.1 0.6 0.5 -1.0 0.2 0.9 -0.5 -0.3 -1.2
Leg predicted mass (left) 0.3 1.6 9.1 -1.0 -0.4 -0.9 -3.0 -1.6 -1.5 -0.9 -1.7 -1.5 -0.7 -0.5 -0.7 -1.7 -0.1 0.4 -0.2
Trunk fat mass 0.3 1.5 4.9 -0.6 -0.1 -0.8 -1.9 -1.0 -1.1 -1.3 -2.2 -1.3 -1.2 -1.8 0.1 -1.6 -0.7 -0.1 -0.9
Waist circumference 0.4 1.3 2.6 -0.9 0.0 -0.9 -1.5 -1.0 -1.6 -1.5 -1.6 -1.6 -1.1 -1.4 0.2 -1.3 -0.6 0.0 -0.9
Number of incorrect matches in round 0.3 0.4 2.1 0.4 -0.3 0.4 -0.3 1.5 0.5 -1.0 0.4 0.9 0.2 0.3 0.4 1.1 -0.2 -0.8 0.2
Past tobacco smoking 0.4 0.7 2.0 -0.5 0.7 -0.9 1.1 0.9 0.6 1.0 -1.3 0.1 0.2 0.6 0.8 1.4 -0.7 -0.7 0.1
Alcohol usually taken with meals 0.6 1.0 4.1 1.1 -0.5 -1.0 2.0 0.5 1.1 1.5 -0.1 0.3 -1.7 -0.2 0.2 -0.4 -1.0 -0.8 0.3
Nervous feelings 1.4 2.6 6.7 0.9 1.6 1.5 0.7 1.1 1.8 -0.4 0.4 2.1 1.3 2.6 2.3 1.2 2.5 -0.3 2.1
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.7 -0.7 1.6 0.6 -0.4 -0.0 -0.1 -0.5 -0.1 0.2 1.0 -0.1 1.2 0.6 0.9 0.4 -0.0
Hearing difficulty/problems with background noise 0.2 0.3 1.0 -0.3 0.2 0.0 0.2 -1.0 -0.2 -0.6 -0.8 -0.2 -0.4 0.6 0.6 0.3 0.1 0.4 0.8
Hair/balding pattern: Pattern 2 1.5 1.9 3.8 -0.4 -1.9 -1.0 -0.1 -1.5 0.2 1.6 1.1 0.1 -1.4 -1.9 -2.0 -1.6 -1.3 -1.2 -1.9
Had menopause 2.1 2.6 13.6 2.1 -1.1 -0.2 1.4 1.4 2.0 0.8 -1.5 1.2 -2.0 -1.1 1.1 -0.1 -1.9 -3.7 -0.2
Had other major operations 0.4 0.4 2.4 -0.1 0.3 -0.5 -0.3 -0.5 1.0 1.1 -0.2 0.7 -0.2 -0.5 0.4 0.3 -0.5 -1.6 -0.4
Forced vital capacity (FVC) 0.1 0.3 1.2 0.4 1.0 0.3 -0.4 1.0 0.1 0.4 -1.1 -0.2 0.6 0.7 -0.1 0.3 0.1 0.2 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 3.3 0.3 1.0 -1.7 -0.9 -0.7 -0.0 -0.9 -1.8 0.2 0.4 -0.4 0.6 0.4 -1.0 -0.7 -0.9
Ever unenthusiastic/disinterested for a whole week 0.8 0.9 2.8 -0.8 1.3 0.3 -1.5 -0.7 -0.6 1.7 0.4 0.7 1.2 -0.5 0.2 0.6 1.1 -0.1 -1.6
Qualifications: None of the above 0.6 1.4 7.9 -1.0 0.2 1.5 -0.9 0.8 -0.3 -0.6 1.1 1.0 1.2 1.4 0.4 1.4 2.8 0.8 0.6
Financial difficulties in last 2 years 0.4 0.5 2.6 -1.2 0.7 0.3 0.1 0.3 -0.7 -0.7 -0.2 -0.2 1.1 -0.2 0.2 -0.4 0.8 1.6 -0.7
Mouth/teeth dental problems 0.1 0.2 1.0 1.0 0.1 -0.5 -0.0 0.5 0.3 0.6 0.8 0.2 0.1 0.3 -0.2 0.8 -0.1 0.1 -0.3
Heart attack 0.4 0.5 1.7 -0.7 1.2 -0.0 -1.0 0.3 -0.6 -0.2 0.3 -0.5 0.8 0.2 1.0 1.3 0.8 0.7 -0.2
Allergy 0.7 1.6 5.4 -2.3 1.4 1.2 0.5 2.1 -0.4 0.7 -1.9 -0.8 0.9 1.0 1.4 1.4 0.3 0.5 1.0
Pain all over the body in last month 0.9 0.9 2.5 0.9 0.0 0.5 -1.0 0.3 1.6 -1.1 0.0 1.4 0.4 1.5 0.3 0.5 1.3 0.7 1.6
Diabetes (self-reported) 0.4 0.6 2.3 1.2 -0.9 -0.5 0.3 0.3 0.8 0.6 -0.1 1.5 -0.4 -1.1 -0.8 -0.4 -0.3 -0.5 -1.1
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.5 0.2 -1.2 -0.9 -0.2 -1.5 -0.9 -1.4 1.3 -0.7 -0.8 -1.1 -1.6 -1.5 0.1 1.9 -0.9
Medication: Ramipril 0.5 0.6 1.8 -0.7 0.3 0.2 0.0 1.0 0.3 -0.1 1.4 0.8 1.2 0.8 0.7 0.6 0.9 1.1 0.4
Medication: Simvastatin 1.0 1.5 5.1 1.6 -2.3 -1.0 0.3 0.5 1.8 0.7 1.0 1.7 -1.7 -0.3 -1.6 -1.1 -0.5 -0.4 0.1
Fluid intelligence score 0.6 1.2 4.0 0.3 -1.1 -0.7 -1.1 -1.4 -0.1 -0.4 0.0 -0.8 -1.4 -1.5 -0.6 -1.8 -2.0 -0.8 -0.5
Illnesses of siblings 1.1 1.6 4.4 -0.6 0.1 -0.8 -1.3 -1.9 -1.7 -0.9 -2.0 -2.1 -0.3 -1.4 0.1 -1.5 -1.4 0.9 -0.5
Neuroticism score 0.5 1.0 3.9 -1.0 1.4 1.4 -0.3 0.6 -0.2 -0.6 0.3 0.4 1.1 1.3 1.0 0.9 2.0 0.4 0.8
Weight 0.4 1.8 7.5 -1.1 0.3 -0.8 -2.6 -1.1 -1.6 -1.1 -2.7 -1.5 -0.7 -1.3 0.0 -1.4 -0.3 0.4 -0.9
Impedance of arm (right) 0.5 2.3 13.0 2.2 -0.2 1.0 3.6 1.6 2.3 0.4 1.0 1.6 -0.7 0.4 1.3 0.4 -0.5 -1.4 1.0
Arm fat percentage (right) 0.2 1.0 3.2 -1.1 0.9 -0.7 -0.7 -0.6 -1.1 -1.2 -1.8 -1.1 -0.4 -1.6 0.7 -0.9 -0.4 0.3 -0.9
Trunk fat-free mass 0.2 0.9 7.3 -0.5 -0.0 -0.5 -2.7 -0.8 -1.0 -0.8 -1.6 -1.1 -0.4 -0.1 0.1 -0.6 0.1 0.2 -0.2
Hip circumference 0.4 1.7 10.0 -1.2 1.1 -0.0 -0.9 -0.9 -0.9 -1.5 -3.2 -1.5 -1.0 -0.9 1.9 -1.1 -0.4 0.0 0.3
Time employed in main current job 1.1 1.3 3.1 1.4 -1.3 0.6 0.0 -1.0 1.6 -1.4 -0.7 0.2 -1.6 0.9 1.0 0.3 -0.2 -1.8 1.6
Alcohol intake versus 10 years previously 0.8 1.2 5.4 -0.3 -0.6 -0.3 -1.7 0.2 -1.2 0.7 -0.3 -0.5 0.8 -1.4 -2.3 -1.1 -0.1 1.3 -1.4
Father’s age at death 0.6 0.9 5.8 -0.1 0.2 -0.6 0.8 -1.2 0.6 1.0 -0.8 -0.2 -0.2 -1.0 0.9 -0.4 -1.1 -2.4 -0.7
Worrier / anxious feelings 0.4 0.7 3.4 0.3 0.2 1.0 -0.6 0.0 1.0 -1.5 0.0 1.3 0.4 1.3 0.2 -0.3 1.8 -0.5 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 3.6 -1.6 -0.6 -0.5 -1.9 -1.3 -1.2 -0.0 -0.9 -1.0 -0.7 -1.2 -0.6 -1.3 0.0 -1.0 -0.9
Falls in the last year 0.8 1.1 2.8 0.5 -0.4 -1.7 -1.0 -0.0 0.7 -1.0 -0.8 0.6 -1.1 -1.5 -0.9 -1.5 -1.5 -1.3 -1.0
Hair/balding pattern: Pattern 3 0.5 0.8 3.3 0.1 1.0 0.2 0.4 0.1 0.6 -1.2 -0.7 0.7 -0.4 -0.5 1.8 0.9 -0.9 -1.7 -0.5
Number of live births 0.8 1.1 2.8 -0.2 1.7 0.6 1.4 0.5 0.6 0.6 -0.8 1.0 1.5 1.0 1.4 1.2 1.5 -0.2 0.5
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.1 -0.7 1.4 0.3 -0.1 0.9 -0.6 1.2 -1.4 -1.0 1.3 0.5 -0.1 0.5 0.4 0.9 -0.1
Pulse rate 0.4 0.6 3.5 -0.0 -0.3 0.2 0.4 1.9 1.0 0.2 -0.2 1.6 -0.1 0.5 -0.6 0.6 0.5 -0.9 -0.6
Happiness 0.4 0.5 1.1 -0.4 0.7 0.6 -0.3 -0.4 -1.0 -0.7 0.3 -0.8 0.6 1.1 0.5 0.4 0.6 0.9 0.9
Noisy workplace 2.8 3.4 10.1 -3.2 2.6 -1.2 -0.9 -0.5 -2.2 -1.0 -2.4 -1.8 2.3 -0.9 0.7 1.9 0.3 2.7 -1.7
Qualifications: A levels/AS levels or equivalent 0.8 1.7 5.2 1.0 -1.3 -1.0 -0.1 -1.5 0.3 0.8 1.1 -0.6 -1.6 -1.5 -1.4 -2.0 -2.3 -1.5 -0.7
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.5 9.7 -3.1 -1.0 0.4 -0.3 1.1 -2.4 0.5 1.8 -3.0 -0.5 -1.6 -1.1 -1.8 0.1 1.2 -0.8
Mouth/teeth dental problems: Dentures 1.3 2.1 8.8 -3.0 1.9 0.1 -0.2 -1.4 -2.4 -0.5 -1.0 -1.8 1.4 -1.1 0.6 0.3 0.1 2.2 -0.6
Asthma 1.2 2.4 13.4 1.5 -1.9 -0.5 -0.7 -2.7 0.8 -0.4 3.7 1.7 -0.4 -0.0 -1.7 -1.8 0.4 -0.7 -0.2
Medication: Ibuprofen (e.g. Nurofen) 2.2 2.8 15.4 0.9 -1.9 -2.0 -3.9 -1.9 0.1 -0.6 -0.4 0.2 -1.5 -1.0 -1.4 -0.8 -2.0 -2.5 -1.1
Medication: Cholesterol lowering 0.5 0.8 3.9 -1.1 -2.0 0.9 -0.5 1.0 -0.1 0.5 1.1 0.2 -0.6 -0.1 -1.4 -0.4 0.8 1.2 0.5
Depression (self-reported) 1.2 1.5 5.1 0.2 -1.2 -1.3 -2.3 -1.2 -0.6 -0.2 -0.2 -0.7 -1.3 -2.1 -0.6 -1.5 -1.6 -1.1 -1.0
Medication: Lansoprazole 0.5 0.5 3.2 -0.7 -0.7 0.6 0.3 -0.1 -0.6 0.0 -0.1 -0.9 -0.6 0.4 0.5 0.2 0.9 0.9 1.8
Prospective memory result 0.9 1.1 6.5 -0.7 1.2 -0.1 -1.2 0.9 -1.0 -0.6 -0.8 -0.9 1.4 -0.2 0.2 0.9 0.9 2.5 -0.1
Lung cancer (father) 1.2 1.4 5.6 2.4 -1.7 -0.6 0.5 0.2 2.0 -0.3 -0.4 1.5 -1.3 0.8 -1.0 -1.2 -0.5 -1.2 0.6
Illnesses of mother 0.4 0.5 1.2 -0.9 1.1 -0.5 -0.6 -0.7 -1.1 -0.8 -0.9 -1.1 0.1 -0.3 0.7 0.4 -0.2 0.4 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.5 1.5 -0.9 1.2 0.2 -0.2 1.1 -0.6 1.1 -1.0 -0.8 0.9 0.1 -0.1 0.4 0.2 0.6 -0.5
Pulse wave Arterial Stiffness index 2.4 2.8 14.2 -3.8 -0.6 0.5 -1.7 -0.3 -3.3 -0.3 1.9 -1.0 0.5 -1.1 -1.7 -0.7 0.7 0.9 -2.2
Impedance of arm (left) 0.5 2.1 9.1 3.0 -0.9 -0.0 2.9 0.7 2.4 -0.1 1.1 1.6 -1.2 0.2 0.4 -0.2 -1.2 -1.4 0.9
Arm fat mass (right) 0.4 1.8 5.1 -1.2 0.6 -1.3 -2.2 -1.5 -1.6 -1.3 -2.3 -1.3 -0.5 -1.7 0.2 -1.4 -0.6 0.4 -1.3
Trunk predicted mass 0.2 0.9 7.5 -0.5 0.1 -0.5 -2.7 -0.9 -1.0 -0.8 -1.6 -1.0 -0.3 -0.1 0.1 -0.6 0.1 0.3 -0.2
Standing height 0.1 0.7 2.8 1.7 -1.4 0.2 -0.9 0.3 0.8 0.6 -1.0 0.2 -1.2 0.5 -0.2 -0.2 -0.4 -0.7 0.5
Length of working week for main job 1.5 1.7 8.7 -1.3 -1.1 -0.3 0.0 -1.2 -1.6 -0.5 -0.8 -1.8 -1.5 -1.2 -1.1 -3.0 -0.5 1.2 -0.0
Exposure to tobacco smoke at home 0.9 1.0 4.4 -0.3 0.6 0.9 -0.5 -0.0 -1.3 -0.1 -1.5 -0.1 1.2 0.8 -1.0 -0.6 1.8 2.1 0.5
Breastfed as a baby 1.2 1.5 5.0 1.9 -2.2 0.4 -0.7 -0.1 1.2 1.5 1.5 0.4 -1.9 1.4 -1.2 -0.3 0.3 -1.1 1.1
Tense / ‘highly strung’ 0.3 0.4 1.9 -0.4 1.4 0.4 -0.2 -0.7 0.2 -0.7 0.7 0.4 1.0 0.3 1.0 -0.2 0.7 -0.2 0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.7 -0.0 1.1 1.2 -0.2 0.2 0.0 -0.6 1.3 0.1 0.4 0.1 1.2 0.8 0.6 -0.7 0.3
Hair/balding pattern: Pattern 4 0.1 0.2 0.9 -0.4 0.5 0.1 0.4 0.9 0.3 0.3 0.9 -0.1 0.2 -0.3 -0.0 0.3 -0.2 -0.2 0.0
Birth weight of first child 1.7 3.2 18.3 0.8 0.5 -0.1 1.9 0.3 2.0 0.5 -4.3 0.7 -2.4 -0.6 2.4 -1.0 -1.1 -3.0 0.1
Peak expiratory flow (PEF) 0.7 1.6 6.0 -1.9 1.8 0.1 -0.2 0.4 -2.4 0.8 -0.2 -2.4 1.4 -0.2 0.0 1.2 -0.1 1.1 -1.0
Pulse wave reflection index 1.8 2.2 6.1 -2.0 -0.8 -0.8 -2.5 -2.1 -2.5 0.0 1.4 -1.1 0.6 -0.9 -1.7 -1.1 -0.5 1.2 -1.6
Ever highly irritable/argumentative for 2 days 0.3 0.3 1.4 0.2 -0.8 0.1 0.4 0.5 0.2 -0.1 0.3 0.4 -0.7 -0.3 -0.9 -1.0 -0.0 -1.2 -0.3
Loud music exposure frequency 1.2 1.3 3.6 -1.3 -0.6 -0.1 -0.8 -1.6 -1.8 -1.1 1.9 -1.4 0.4 -0.9 -1.2 -1.0 0.2 1.4 -0.5
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 4.3 1.4 -0.1 -0.3 -0.1 -1.4 0.5 2.1 0.8 0.1 -0.6 0.1 -0.1 -0.5 -1.0 -1.5 -0.0
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 7.0 0.7 -2.0 -0.6 -1.1 -1.0 0.5 -0.8 0.1 0.1 -1.4 -1.2 -1.7 -2.6 -0.9 0.5 -0.3
Blood clot in the leg (DVT) 1.3 1.6 4.3 0.6 0.1 -1.8 -1.5 -1.1 0.5 0.2 -2.0 0.3 -0.8 -1.6 0.8 -0.1 -1.7 -1.9 -2.1
Medication: Paracetamol 1.0 1.7 5.5 -2.2 0.7 -0.5 -0.8 -2.4 -2.2 0.1 -0.9 -1.6 0.9 -0.9 -0.5 -1.2 0.3 1.3 -1.1
Headache pain in last month 0.2 0.3 1.9 -0.4 -0.4 -0.3 0.1 -0.8 -0.6 0.5 -0.4 -1.4 -0.8 -0.5 0.4 -0.5 -0.2 0.1 0.5
Medication for cholesterol, blood pressure or diabetes 1.4 2.4 10.2 1.0 2.9 -0.3 1.3 -0.7 0.2 -0.8 -3.2 -1.2 1.0 0.5 3.2 1.0 -0.9 -0.4 1.1
Glaucoma (self-reported) 1.0 1.2 4.0 1.6 0.3 0.1 -0.4 0.8 2.0 1.2 0.3 1.5 0.3 1.2 1.5 1.0 -0.0 -1.4 0.8
Gout (self-reported) 0.8 1.1 2.7 -0.7 0.9 1.1 0.3 0.2 -1.0 -1.0 -1.6 -1.0 1.1 1.1 0.9 -0.2 1.3 1.5 1.4
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 1.3 1.0 0.0 -0.5 0.6 -1.1 -0.4 -1.1 -0.2 -0.4 -0.4 -0.5 -0.2 -0.1 -0.6 0.2 -0.4
Medication: Amlodipine 2.3 3.2 17.2 -0.5 -3.1 -0.3 -1.8 -0.8 -0.2 0.9 3.6 1.1 -0.4 0.2 -4.2 -1.6 1.1 1.1 -0.1
Medication: Ventolin 100micrograms inhaler 1.0 1.3 10.0 -0.1 -0.1 -0.2 -0.2 -1.1 0.1 -0.3 3.2 1.6 0.8 0.5 -1.7 0.0 1.0 1.5 -0.3
Birth weight 0.5 1.0 4.2 -0.2 -0.3 -0.4 -2.0 -1.7 -0.9 -0.5 -1.8 -0.6 -1.2 -0.7 1.0 -0.5 -0.1 -0.7 -0.5
Chronic bronchitis/emphysema (mother) 0.5 0.6 2.7 -0.1 -0.3 0.8 -0.1 0.2 -0.6 -1.6 0.0 -0.9 1.2 0.6 -0.0 -0.4 0.2 1.3 0.8
High blood pressure (siblings) 2.0 2.9 8.5 1.4 0.3 0.5 1.4 1.3 1.7 -0.2 2.9 2.1 1.2 2.9 0.2 2.0 2.6 0.7 1.6
Forced vital capacity (FVC), Best measure 0.1 0.3 1.1 0.3 0.9 0.2 -0.3 1.0 0.3 0.8 -0.8 -0.2 0.4 0.5 0.2 0.6 -0.0 -0.2 0.1
Body fat percentage 0.3 1.3 5.6 -0.7 0.5 -0.9 -1.2 -0.9 -1.0 -1.3 -2.4 -1.1 -0.9 -2.0 0.5 -1.2 -0.8 0.0 -1.2
Leg fat percentage (right) 0.3 1.2 6.4 -1.3 1.1 -0.4 -1.3 -0.3 -1.2 -0.8 -2.5 -1.2 -0.3 -1.6 0.9 -0.4 -0.5 0.2 -0.9
Arm fat-free mass (right) 0.4 2.0 13.5 -1.2 -0.1 -0.9 -3.7 -1.2 -2.0 -0.5 -1.9 -1.8 -0.2 -0.8 -0.9 -0.9 0.0 0.6 -1.2
Exposure to tobacco smoke outside home 1.6 2.1 6.7 -2.6 2.2 1.7 0.5 0.5 -1.8 0.1 -0.3 -0.9 2.6 0.2 1.3 0.7 1.7 1.7 0.3
Comparative body size at age 10 0.7 2.0 5.8 0.1 -0.1 -2.2 -1.6 -2.1 -0.3 -1.8 -2.4 0.4 -1.4 -1.3 -0.6 -0.4 -1.7 -1.1 -1.7
Number of full brothers 0.8 1.0 3.2 -1.8 0.2 0.5 -1.3 -0.5 -1.3 1.6 1.8 -0.3 0.5 0.4 -0.8 0.1 1.3 0.3 -0.7
Worry too long after embarrassment 0.2 0.3 1.4 0.8 0.1 0.3 -0.4 0.6 0.6 -0.1 0.7 1.2 0.4 0.7 -0.3 0.2 0.9 -0.3 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 4.7 -0.0 -0.5 0.4 -2.0 0.5 0.4 -1.6 0.3 0.2 -0.3 -0.0 0.5 0.5 -0.1 -2.2 -0.3
Wheeze or whistling in the chest in last year 1.0 1.7 6.5 -0.2 0.1 -1.1 -0.9 -2.0 -0.1 1.1 1.0 1.4 0.3 -1.9 -2.0 -1.5 -0.6 -1.0 -2.5
Number of children fathered 0.5 0.6 3.1 0.3 0.8 -1.6 -0.4 -0.2 0.1 -0.0 -1.2 0.1 -0.2 -1.1 0.2 -0.2 -1.8 0.3 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 2.4 0.6 0.0 1.1 1.5 0.9 1.2 1.5 0.3 1.0 -0.2 0.6 0.4 1.2 0.8 -1.3 -0.3
Age at first live birth 0.4 0.8 3.7 0.8 -1.9 0.4 0.8 0.8 0.3 0.5 0.1 -0.1 -1.5 0.3 -0.9 -1.2 -0.2 -1.1 0.8
Pulse wave peak to peak time 2.2 2.6 13.2 3.6 0.5 -0.3 1.7 0.2 3.1 0.3 -2.0 0.9 -0.6 1.1 1.7 0.5 -0.5 -0.6 2.3
Health satisfaction 0.4 0.5 2.1 -1.1 0.7 0.2 -0.6 -0.0 -0.6 0.8 1.4 0.4 0.6 0.4 -0.1 0.4 1.3 0.3 -0.4
Shortness of breath walking on level ground 0.6 0.7 2.2 -1.1 -0.0 -0.9 -1.4 -0.8 -0.4 1.5 0.1 0.1 0.0 -1.1 -1.0 -0.4 -0.5 -0.3 -1.4
Qualifications: College or University degree 0.7 2.2 8.4 1.6 -1.1 -0.9 1.1 -0.2 1.8 1.4 0.0 0.0 -2.4 -1.9 -0.2 -1.0 -2.9 -2.0 -0.8
Eye problems/disorders: None of the above 1.0 1.2 6.1 -2.5 -0.4 -0.4 -1.0 -0.6 -2.3 -0.2 -0.1 -1.8 -0.2 -1.0 -0.3 -0.8 -0.5 -0.0 -0.6
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.4 0.8 -0.1 1.0 0.8 0.2 1.2 -1.2 0.9 1.1 0.6 0.7 -0.1 0.6 1.1 -0.8 0.5
Emphysema/chronic bronchitis 0.8 0.9 3.1 1.1 -0.1 -0.8 0.3 -1.8 1.6 -0.1 0.3 1.5 -0.4 -0.3 -0.5 -1.3 -0.4 -1.5 -0.1
Medication for pain relief, constipation, heartburn 0.7 1.2 3.1 0.7 0.7 1.3 1.8 1.7 1.1 -0.9 0.8 0.5 0.3 1.2 1.4 1.5 0.4 0.6 1.4
Neck or shoulder pain in last month 0.5 0.7 2.3 0.9 0.4 -0.4 -0.0 0.8 1.5 -1.0 -0.4 1.0 -0.1 1.2 0.9 0.1 0.1 -0.3 1.5
Medication: Blood pressure 2.0 3.6 15.4 -2.1 -3.1 0.5 -1.7 0.7 -1.0 0.7 3.9 0.6 -0.8 -0.7 -3.9 -1.5 1.2 0.5 -1.3
Angina (self-reported) 0.6 0.8 3.9 -1.4 1.3 -0.5 -0.8 -1.0 -0.8 0.3 -0.4 -0.1 2.0 -0.6 0.7 0.2 0.8 0.7 -0.9
Migraine (self-reported) 1.0 1.3 3.8 -0.9 -0.7 -1.3 -0.8 -1.6 -0.6 -0.2 -1.0 -0.8 -1.0 -2.0 -0.8 -1.4 -1.9 0.4 -1.1
Medication: Ibuprofen 2.8 3.3 16.3 0.7 -2.0 -2.0 -4.0 -1.8 -0.6 -2.1 -0.8 -0.5 -1.6 -1.7 -1.6 -1.4 -2.1 -1.7 -1.7
Medication: Allopurinol 1.4 1.8 5.2 0.4 2.0 1.2 0.6 0.4 0.6 -0.3 -1.0 0.9 1.9 2.0 2.3 1.6 1.9 0.1 1.2
Medication: Omeprazole 0.6 0.7 5.4 0.1 -0.6 0.5 0.4 0.1 1.0 0.0 0.6 0.7 -0.8 -0.5 -0.4 -1.2 -0.5 -2.3 -0.2
Medication: Seretide 50 evohaler 0.4 0.5 4.1 0.2 0.8 -0.6 -0.5 -2.0 -0.3 1.1 -0.1 0.1 0.4 -0.1 0.3 -0.5 -0.4 -0.4 -0.2
Mean time to correctly identify matches 0.3 0.6 1.5 0.9 -0.6 0.6 -0.2 1.2 0.9 0.6 1.2 1.0 0.1 -0.4 0.1 0.7 -0.2 -1.2 -0.5
Heart disease (mother) 0.3 0.4 3.5 -0.2 0.5 0.3 -0.4 -0.9 -0.3 1.9 1.0 -0.4 0.3 -0.4 0.4 0.5 -0.2 0.0 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.9 -0.5 1.4 -0.0 1.4 -0.4 -0.4 0.8 -1.1 0.2 0.8 -0.1 0.4 0.5 0.6 0.5 -0.3
Whole body fat mass 0.5 2.1 5.8 -1.0 0.0 -1.1 -2.3 -1.5 -1.5 -1.4 -2.4 -1.5 -1.1 -2.1 -0.1 -1.8 -0.8 0.1 -1.4
Leg fat mass (right) 0.6 2.2 7.6 -1.4 0.3 -0.9 -2.8 -1.3 -1.8 -1.3 -2.6 -1.8 -0.7 -1.9 0.1 -1.4 -0.7 0.3 -1.2
Arm predicted mass (right) 0.4 2.1 13.5 -1.2 -0.3 -1.1 -3.7 -1.5 -1.8 -0.7 -2.1 -1.6 -0.4 -0.8 -1.0 -1.1 -0.1 0.4 -1.1
Pulse rate, automated reading 0.6 1.9 4.6 -0.4 -1.3 -1.9 -0.7 -0.7 -0.5 -1.4 -0.2 -0.5 -1.6 -2.1 -1.4 -1.5 -1.8 -1.4 -2.0
Alcohol intake frequency. 0.2 0.4 2.2 -1.1 0.2 0.4 1.5 0.4 -0.3 0.2 0.9 -0.3 0.1 -0.2 -0.4 -0.2 -0.4 -0.6 -0.3
Comparative height size at age 10 0.2 1.1 8.6 0.5 -0.5 -0.4 -2.1 -0.4 -0.1 1.4 -2.9 -0.0 -0.6 -0.2 0.2 0.5 -0.2 -1.3 -0.3
Number of full sisters 1.6 1.9 5.0 1.4 1.2 1.7 1.0 0.0 1.3 0.4 0.6 1.3 1.8 2.2 1.5 0.8 2.2 0.0 1.9
Suffer from ‘nerves’ 0.6 0.9 3.0 -0.4 1.3 0.8 -0.1 1.1 -0.2 -0.4 1.2 0.5 1.4 1.2 0.4 1.7 1.4 0.4 0.6
Overall health rating 0.4 0.8 2.6 -0.8 -0.9 -0.5 -1.4 -0.1 -0.5 -0.7 0.6 0.5 -0.6 -0.6 -1.6 -1.6 1.0 0.6 -0.8
Chest pain or discomfort 1.5 2.2 6.3 -1.1 -1.6 -1.0 -2.1 -1.6 -0.8 -1.0 1.6 -0.6 -1.0 -2.1 -2.0 -2.5 -1.0 0.1 -1.6
Had major operations 2.0 2.3 8.4 2.0 -1.4 1.1 0.9 0.5 2.1 0.9 2.9 1.4 -1.0 2.0 1.0 -0.5 0.9 -0.8 2.4
Age at last live birth 0.4 0.6 2.4 0.9 -1.2 0.2 1.6 0.6 1.0 0.5 -0.1 0.6 -0.9 0.1 -0.6 -0.4 -0.2 -0.8 0.5
Family relationship satisfaction 0.7 0.8 3.5 -0.8 1.5 0.5 0.3 0.7 -1.0 0.2 -0.8 -0.9 1.5 0.1 0.4 1.9 0.2 0.6 -0.6
Leg pain on walking 1.7 2.2 6.7 -2.6 1.9 1.2 -0.3 0.9 -1.3 2.0 -0.1 -0.6 2.4 1.0 0.6 1.2 2.5 1.2 0.2
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.7 4.8 0.1 1.7 0.7 1.8 0.2 0.4 -0.3 -0.1 0.5 2.0 2.2 0.4 0.6 1.6 1.8 2.0
Commuting to job workplace: Car/motor vehicle 0.6 0.7 3.0 0.1 0.6 0.3 0.4 0.3 -0.2 -1.5 -1.2 0.5 0.8 0.4 -0.1 -1.0 1.2 1.7 0.0
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 3.2 0.8 0.6 1.4 1.6 -0.1 0.7 -0.1 0.2 0.4 1.0 1.7 1.2 1.3 1.1 -0.4 1.8
Medication: Aspirin 0.3 0.4 2.1 0.7 0.1 -0.3 1.1 0.9 -0.0 -0.3 1.5 0.5 0.4 -0.1 -0.4 -0.1 0.2 0.8 -0.0
Supplements: Vitamin C 0.4 0.5 2.8 0.1 0.5 0.7 0.3 0.3 0.9 0.3 1.7 0.9 -0.6 0.2 1.0 0.4 0.4 -1.0 -0.1
Knee pain experienced in last month 0.8 1.2 5.0 -1.8 -0.1 0.7 -1.2 -0.6 -1.2 -0.1 2.2 -0.5 1.0 -0.4 -1.2 -0.3 1.4 1.3 -0.7
Hypertension (Self-reported) 1.8 5.0 37.9 0.5 -3.6 -0.3 -1.2 0.9 0.6 -1.3 6.2 1.7 -0.6 0.9 -3.5 -1.4 2.0 1.1 0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.4 2.8 13.1 1.6 -2.1 2.0 1.2 1.0 1.8 -0.4 1.1 1.2 -1.1 2.7 0.2 0.1 1.6 -0.6 3.6
Illnesses of father: Heart disease 0.3 0.5 2.8 0.1 0.3 -0.3 0.4 -0.1 0.9 1.7 0.1 1.5 0.5 0.0 -0.3 0.2 0.7 0.4 -0.5
Illnesses of siblings: Diabetes 1.1 1.4 6.5 0.7 0.2 0.1 1.6 1.2 2.5 0.9 1.5 2.0 -0.0 0.2 0.2 1.5 0.1 -0.9 -0.2
Smoking status: Previous 0.3 0.5 1.7 1.1 -1.2 0.5 -0.6 -0.2 0.0 -0.5 0.6 0.3 -0.5 -0.5 -1.1 -1.3 0.3 0.5 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 3.8 1.3 -0.4 1.0 -0.7 0.2 0.4 1.1 1.9 0.8 0.1 0.8 0.0 0.2 1.1 -0.6 0.2
Whole body fat-free mass 0.2 1.4 8.8 -1.0 0.0 -0.7 -3.0 -1.2 -1.5 -0.9 -1.8 -1.4 -0.3 -0.3 -0.3 -1.1 0.2 0.6 -0.3
Leg fat-free mass (right) 0.3 1.8 9.1 -1.6 -0.2 -0.8 -3.0 -1.7 -1.9 -1.0 -1.6 -1.7 -0.5 -0.6 -0.9 -1.6 0.1 0.8 -0.5
Arm fat percentage (left) 0.3 1.4 3.8 -0.7 0.4 -1.3 -1.3 -1.2 -1.1 -1.3 -1.8 -1.1 -0.7 -1.9 0.1 -1.5 -0.9 0.2 -1.2
Average weekly red wine intake 1.4 2.1 6.0 2.4 -0.2 -0.0 1.8 1.2 2.5 1.6 1.3 2.2 -1.2 0.1 0.9 -0.4 -0.7 -2.1 0.4
Handedness (chirality/laterality): Left-handed 0.6 0.7 3.6 -0.8 -0.2 -0.6 0.0 -0.4 -0.1 0.7 1.2 0.2 -0.2 -1.0 -0.4 0.3 -0.9 -1.9 -1.5
Mood swings 0.3 0.5 1.5 -1.2 0.9 0.5 -0.9 -0.8 -0.5 0.5 -0.2 0.1 0.1 0.3 0.5 1.2 1.0 -0.1 -0.1
Loneliness, isolation 0.3 0.5 1.6 -1.2 -0.1 0.8 -1.3 -1.1 0.3 -0.1 0.1 0.4 -0.4 -0.8 -0.0 -0.6 0.3 -0.9 -0.4
Long-standing illness, disability or infirmity 0.4 0.7 2.3 -1.5 -0.4 -0.3 -0.3 0.0 -0.7 0.7 1.5 -0.1 0.1 -0.6 -1.4 -1.0 0.4 1.0 -0.8
Ever had bowel cancer screening 0.5 0.6 1.9 0.8 -0.5 -0.2 0.6 1.0 0.8 -0.9 -0.3 0.2 -1.2 -0.6 0.1 -0.9 -1.4 -0.5 0.2
Diabetes diagnosed by doctor 0.6 0.9 3.6 1.7 -1.4 -0.3 -0.2 0.5 1.1 0.5 0.4 1.9 -0.8 -0.6 -1.0 -0.4 -0.2 -1.1 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.8 -0.6 -0.6 0.5 0.8 -0.3 -0.3 -0.3 1.7 -0.3 0.5 0.2 -1.2 -0.4 0.5 1.3 0.3
Friendships satisfaction 0.4 0.5 2.0 -1.0 1.4 0.2 0.1 0.4 -0.7 -0.2 0.6 -0.5 1.3 0.0 0.3 1.2 0.1 1.0 -0.4
Qualifications: nursing, teaching 2.1 3.2 10.1 1.8 -0.9 -2.5 0.1 -1.0 0.9 1.1 0.5 0.4 -1.4 -3.1 -1.7 -1.7 -3.2 -1.8 -2.8
Commuting to job workplace: Walk 0.8 0.9 4.2 0.2 -1.3 0.9 -0.7 0.9 -0.5 0.6 0.9 -1.1 -2.0 -0.0 0.5 0.4 -0.5 -1.4 0.7
Eye problems/disorders: Cataract 0.7 0.9 5.5 0.6 1.5 -0.9 0.5 -0.7 -0.8 -0.6 -0.1 -0.5 1.3 -0.0 -0.1 0.7 0.4 2.4 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.5 0.9 5.7 0.9 0.0 0.4 0.1 0.8 0.9 0.0 -1.2 0.9 -0.4 1.0 1.1 0.9 -0.1 -2.4 0.4
Medication for cholesterol 0.5 0.7 4.5 -0.6 1.1 0.7 -0.4 -1.1 -0.3 0.3 -2.1 -0.8 0.3 0.3 0.9 -0.4 -0.2 0.9 0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.2 8.4 -1.4 0.5 -0.8 0.1 0.5 -0.8 0.5 -2.9 -1.0 -0.7 -1.7 0.2 -0.9 -1.2 -0.2 -0.9
Back pain experienced in last month 0.8 1.2 9.9 -1.0 0.6 -0.4 0.5 0.5 -0.9 0.7 -3.1 -0.7 -0.5 -1.1 -0.9 -0.8 -0.1 0.6 -1.2
Mineral and other dietary supplements 0.5 0.6 1.9 0.5 0.1 -0.9 -0.4 -1.1 -0.3 -1.4 -0.4 -0.4 -0.3 1.3 -0.3 -0.7 -0.5 1.0 1.3
Breast cancer (self-reported) 0.6 0.8 2.8 1.3 0.7 0.7 0.1 0.6 1.5 -0.2 -0.5 1.7 0.0 0.6 1.3 0.8 0.4 0.3 0.8
Asthma (self-reported) 1.2 2.3 12.2 1.4 -1.9 -0.4 -0.8 -2.6 0.9 -0.8 3.5 1.8 -0.3 0.1 -1.9 -1.7 0.5 -0.7 -0.2
Osteoporosis (self-reported) 2.1 2.6 6.8 1.2 -1.9 -0.4 1.4 2.2 2.2 2.1 -0.1 1.8 -2.1 -0.7 -1.2 -0.6 -1.7 -2.6 -0.3
Osteoarthritis (self-reported) 0.4 0.5 2.3 -1.5 0.6 -0.3 -0.8 0.9 -0.7 0.6 0.2 0.5 0.0 -0.2 0.9 1.2 -0.2 -0.7 -0.6
Medication: Aspirin 0.3 0.4 1.3 0.6 -0.2 -1.0 0.5 0.5 -0.5 -0.6 1.1 0.3 0.1 -0.6 -0.8 -0.4 -0.2 0.8 -0.5
Medication: Gliclazide 0.4 0.4 2.0 0.5 0.1 1.4 0.1 0.0 0.6 0.2 0.5 0.5 0.6 0.1 1.1 0.1 1.4 0.3 0.5
Illnesses of father: None of the above (group 1) 0.5 0.6 2.0 0.0 0.6 1.2 0.1 0.8 -0.1 -0.4 -1.4 -0.5 0.5 1.0 0.9 1.0 0.8 -0.7 0.8
Smoking status: Current 0.7 1.1 6.1 -1.1 0.9 1.5 -0.2 -1.4 -0.3 -0.2 2.5 0.9 1.5 0.4 -0.1 0.2 1.3 0.1 -0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 2.6 -1.6 1.5 -0.3 -0.4 0.4 -1.3 0.4 -0.5 -1.4 1.4 -0.2 -0.0 0.7 0.0 1.4 -0.8
Whole body water mass 0.2 1.3 8.6 -0.9 0.0 -0.6 -2.9 -1.1 -1.4 -0.8 -1.9 -1.3 -0.3 -0.3 -0.3 -1.0 0.2 0.5 -0.4
Leg predicted mass (right) 0.3 1.8 9.3 -1.6 -0.2 -0.8 -3.0 -1.7 -1.9 -1.0 -1.5 -1.6 -0.5 -0.6 -0.9 -1.6 0.2 0.8 -0.5
Arm fat mass (left) 0.6 2.3 6.7 -1.0 0.1 -1.7 -2.6 -1.6 -1.6 -1.3 -2.1 -1.4 -0.9 -2.3 -0.4 -1.9 -1.0 0.2 -1.7
Number of self-reported non-cancer illnesses 1.2 2.1 9.4 0.3 -2.5 -1.1 -0.5 -0.8 0.2 -1.0 3.1 1.3 -1.3 -0.6 -2.8 -1.2 0.0 -0.1 -1.0
Average weekly champagne plus white wine intake 0.5 0.8 2.1 0.1 -0.8 0.5 0.7 1.4 0.3 1.1 0.1 -0.2 -0.9 -1.4 -0.3 0.3 -0.6 -1.4 -1.4
Miserableness 0.4 0.6 2.5 -1.0 1.3 0.0 -1.0 -0.5 -1.0 0.7 -1.6 -0.5 0.1 -0.7 0.4 -0.6 0.4 0.4 -0.7
Guilty feelings 0.5 0.8 3.2 -1.1 1.3 0.3 -1.0 0.4 -1.5 0.4 0.2 -0.5 1.0 0.2 -0.3 0.7 0.9 1.8 -0.6
Wears glasses or contact lenses 1.4 1.6 7.0 0.5 -0.4 -1.1 -0.1 1.0 0.2 -0.1 -0.4 -1.3 -2.1 -1.3 1.8 0.3 -2.6 -2.2 -0.2
Ever taken oral contraceptive pill 0.7 0.8 3.2 0.8 0.2 0.3 1.8 1.1 1.3 1.4 0.8 1.2 0.1 0.2 -0.5 1.0 -0.1 -0.6 -0.5
Hearing aid user 0.9 1.0 3.3 -1.5 -0.6 0.7 0.6 -0.8 -1.1 -1.8 -0.0 -1.6 -0.7 -0.6 -0.1 -1.5 0.2 1.1 0.5
Mother’s age at death 1.1 1.4 7.2 0.2 1.8 0.9 2.7 0.7 0.2 -0.6 -2.0 -0.0 0.2 0.1 2.2 0.7 -0.2 0.6 0.9
Financial situation satisfaction 0.5 0.6 4.1 -2.0 0.7 0.2 -0.3 0.2 -1.0 0.1 -0.6 -1.0 0.5 -0.8 0.6 -0.5 0.0 1.0 -0.3
Tinnitus: Yes, now most or all of the time 0.8 0.9 6.1 -0.6 0.9 0.9 0.6 -0.1 -1.4 -0.3 0.2 -0.8 0.5 0.8 0.4 0.6 1.2 2.5 0.8
Commuting to job workplace: Public transport 0.4 0.4 1.6 1.2 0.1 -1.1 -0.1 -0.6 0.5 -0.4 0.6 0.1 -0.6 -0.6 0.3 -0.5 -1.3 -0.5 -0.0
Eye problems/disorders: Glaucoma 1.1 1.3 5.4 1.1 0.0 -0.5 -0.4 0.9 1.7 2.2 -1.2 1.1 -0.2 0.2 0.6 0.7 -1.0 -2.3 -0.3
Medication: Blood pressure 1.5 2.9 16.6 1.2 -1.3 0.7 0.4 1.4 1.5 0.8 4.1 2.2 0.6 2.2 -0.1 0.8 2.7 0.8 1.6
Pain type(s) experienced in last month: Hip pain 0.7 0.9 5.1 -0.8 0.9 -1.6 -0.8 -0.0 -0.2 0.6 -1.1 1.1 0.5 -0.5 -1.0 0.0 0.0 -0.4 -2.3
Supplements: Fish oil (including cod liver oil) 0.8 1.0 4.5 0.1 0.5 0.7 1.1 1.2 0.4 0.9 -0.1 0.1 -0.1 -1.4 1.4 1.0 -0.6 -2.1 -1.4
High cholesterol (Self-reported) 1.0 1.8 7.2 1.2 -2.5 -0.9 -0.4 0.6 0.6 -1.1 1.4 1.3 -1.4 -0.9 -2.7 -1.5 -0.8 0.4 -1.0
Medication: Bendroflumethiazide 1.7 2.6 10.0 0.4 -3.2 -0.1 0.2 0.3 1.1 0.6 2.1 2.0 -2.2 -1.0 -2.7 -2.2 0.3 -1.0 -1.4
Medication: Paracetamol 1.2 1.9 6.7 -1.4 0.8 -1.4 -1.0 -2.6 -1.7 -1.2 -1.5 -1.3 0.7 -1.5 -0.7 -1.5 -0.3 1.4 -1.4
Medication: Lisinopril 0.7 1.0 3.2 -0.1 -0.8 -1.1 -0.8 -0.9 -1.2 -1.2 0.2 -0.2 -0.3 -1.4 -1.8 -1.1 -0.3 0.6 -1.5
Medication: Atorvastatin 0.8 1.0 4.7 -0.9 -0.5 0.4 -0.5 0.3 -1.2 -2.2 1.2 -0.2 0.4 -0.8 -1.6 -0.1 0.4 0.4 -1.6
Illnesses of father: High blood pressure 0.7 0.9 3.4 0.8 -1.7 0.1 0.8 1.1 1.0 0.3 1.9 0.8 -0.9 -0.2 -0.9 -1.1 -0.8 0.1 0.6
Alcohol drinker status: Never 0.8 1.0 10.5 0.5 -0.0 1.0 3.2 0.9 0.2 0.8 -0.7 -0.1 -0.5 0.3 0.8 0.3 -0.5 -0.5 0.6
Ever smoked 0.7 1.2 4.8 -0.1 -0.0 -0.1 -2.2 -1.6 -1.5 -1.6 1.5 -0.6 0.3 -0.9 -0.8 -1.3 -0.0 0.8 -0.7
Basal metabolic rate 0.3 1.7 9.5 -1.2 0.1 -0.9 -3.1 -1.4 -1.7 -1.0 -2.1 -1.6 -0.4 -0.7 -0.3 -1.2 -0.0 0.5 -0.7
Leg fat percentage (left) 0.5 1.9 6.0 -2.0 1.3 -0.6 -1.3 -0.6 -1.9 -1.0 -2.4 -1.5 -0.1 -2.2 0.4 -0.7 -0.4 0.7 -1.6
Arm fat-free mass (left) 0.4 1.8 10.6 -1.6 0.3 -0.8 -3.3 -1.0 -1.9 -0.6 -2.2 -1.6 -0.1 -0.8 -0.3 -0.7 0.1 0.4 -1.1
Number of operations (self-reported) 0.9 1.4 4.6 1.8 0.6 0.4 0.6 -0.3 2.1 1.5 0.7 2.1 0.2 0.9 1.4 0.5 0.1 -1.7 0.4
Average weekly beer plus cider intake 0.4 0.5 2.0 -0.2 0.1 0.2 -0.9 1.2 -0.3 -1.0 -1.4 0.1 0.9 0.2 -0.9 -0.0 0.7 0.8 -0.6
Irritability 1.5 2.6 10.4 -0.6 0.5 3.2 1.5 2.0 1.5 0.3 0.9 1.3 0.4 2.0 1.7 1.2 2.4 -1.1 2.0
Risk taking 1.6 2.3 5.2 -0.8 -1.3 -0.9 -1.0 -0.6 -1.7 -0.8 -1.8 -2.1 -2.0 -2.3 -1.5 -2.2 -1.6 0.9 -1.6
Ever had prostate specific antigen (PSA) test 3.0 3.5 9.5 1.3 1.6 1.8 1.6 1.2 2.0 0.5 0.0 2.3 1.9 3.1 2.1 2.4 2.4 0.2 2.5
Fractured/broken bones in last 5 years 1.0 1.2 4.2 0.7 -1.2 -1.5 -1.1 -0.0 -0.2 0.5 -0.8 0.2 -1.4 -0.9 -1.2 -2.1 -1.7 -1.2 -0.8
Age started oral contraceptive pill 0.5 0.7 4.1 -0.0 -0.5 0.1 0.8 0.4 0.9 -1.7 -0.3 -0.0 -1.0 0.2 0.7 -0.2 -0.6 -2.0 0.3
Diastolic blood pressure, automated reading 1.9 6.0 30.5 0.2 -3.4 -2.8 -1.4 1.2 -0.9 -1.0 4.6 1.3 0.6 -0.2 -5.5 -2.9 0.4 2.6 -1.2
Ever depressed for a whole week 1.0 1.2 6.4 -0.5 1.1 -1.4 -2.5 -1.9 0.0 0.3 0.8 1.0 0.5 -0.4 0.7 0.6 0.0 -1.3 -1.3
Unable to work because of sickness or disability 0.7 0.9 4.8 -1.2 -0.0 1.4 -0.9 0.2 -0.5 0.4 2.2 0.4 0.6 -0.8 -0.6 -0.6 1.4 0.9 -0.5
Commuting to job workplace: Cycle 0.6 0.7 3.7 0.4 0.9 0.5 0.2 -1.1 1.0 0.6 0.9 0.3 0.1 0.2 1.9 0.3 -0.4 -0.5 1.3
Myopia 0.3 0.4 1.2 0.2 -0.6 0.4 -1.0 1.1 -0.6 0.7 0.8 -0.6 -0.4 -1.0 0.2 0.1 -0.2 -0.7 -0.9
Vascular/heart problems diagnosed by doctor 1.3 3.4 27.9 0.4 2.8 0.5 0.9 -0.6 -0.1 1.1 -5.3 -1.1 0.5 -0.4 2.7 1.2 -1.8 -1.7 -0.3
Cholesterol lowering medication 1.0 1.4 2.8 1.5 -1.4 -1.5 0.5 0.5 1.0 -0.7 1.0 1.0 -1.4 -1.2 -1.2 -0.9 -1.4 -1.7 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 2.0 -0.3 -0.4 0.6 0.4 0.3 0.2 0.2 0.9 -0.2 -0.9 -0.5 -0.2 -0.9 -0.5 -1.4 0.1
Pain experienced in last month 0.2 0.4 1.4 0.9 -0.2 0.6 1.2 0.7 0.2 0.6 0.5 0.4 0.1 -0.8 -0.1 0.3 -1.0 -0.2 -0.6
Supplements: Calcium 0.5 0.6 1.9 0.6 -0.8 1.1 0.2 0.8 0.4 0.6 1.4 0.6 -0.7 -0.9 -0.9 -0.0 -0.0 -0.8 -0.9
Basal cell carcinoma (self-reported) 0.6 0.7 2.5 -0.7 0.6 -1.2 -0.9 -1.3 -1.2 -0.3 -0.1 -0.7 0.5 -0.7 -0.4 0.1 -1.0 0.2 -1.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.5 -0.6 0.9 0.0 -0.9 0.4 -0.4 -0.2 0.3 -0.5 0.6 0.3 0.8 1.2 0.6 0.5 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.3 1.7 4.0 0.6 -0.3 -1.8 -1.8 -1.6 0.4 0.0 -1.7 0.2 -1.1 -1.7 0.4 -0.4 -1.8 -1.9 -2.0
Heart disease (siblings) 0.3 0.4 1.7 0.0 -0.4 1.1 -0.1 0.9 -0.5 1.2 1.3 0.2 -0.0 -0.2 -0.2 0.2 0.3 -0.3 -0.3
Alcohol drinker status: Previous 0.7 0.8 3.0 0.2 0.0 -0.8 -1.2 -1.4 1.2 -1.3 1.2 1.7 0.5 -0.2 -0.9 -0.5 -0.3 -0.6 -0.6
Pack years of smoking 0.8 1.1 5.3 -1.7 0.8 -0.4 0.4 0.1 -0.1 -0.5 -2.3 -0.1 0.3 -1.8 -0.1 -0.3 -0.9 -0.5 -1.9
Impedance of whole body 0.3 1.3 7.2 2.1 -0.2 0.4 2.7 1.2 1.8 0.5 0.6 1.2 -0.4 -0.2 0.4 0.5 -0.8 -1.1 0.1
Leg fat mass (left) 0.7 2.7 7.3 -1.8 0.4 -1.1 -2.7 -1.5 -2.2 -1.5 -2.5 -1.9 -0.6 -2.2 -0.2 -1.6 -0.7 0.6 -1.7
Arm predicted mass (left) 0.4 2.0 10.3 -1.7 0.5 -0.9 -3.2 -1.0 -2.2 -0.6 -2.3 -1.8 -0.1 -0.9 -0.3 -0.5 0.1 0.8 -1.3