Hub : Genes

ANK1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.1900 0.0710 2.3e-03 0.080 NA 0.121 NA 0.126 3.3e-05 NA 3.4e-07 NA 1.9e-07
2 GTEx Nerve Tibial 0.1620 0.0678 5.7e-04 0.005 NA 0.019 NA 0.013 1.4e-01 NA 1.6e-02 NA 4.1e-02
3 METSIM Adipose 0.0439 0.0167 1.4e-03 0.050 0.014 0.031 0.030 0.038 4.9e-08 2.6e-03 1.6e-05 2.2e-05 2.0e-06
4 NTR Blood 0.0307 0.0109 3.5e-04 0.020 0.011 0.011 0.013 0.016 3.1e-07 9.8e-05 9.1e-05 4.4e-05 4.7e-06
5 TCGA Breast Invasive Carcinoma 0.0432 0.0167 1.5e-04 0.015 0.019 0.025 NA 0.023 3.9e-04 7.1e-05 6.1e-06 NA 1.3e-05
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0750 0.0363 3.9e-03 0.004 0.007 0.003 NA -0.002 1.1e-01 5.0e-02 1.3e-01 NA 6.8e-01
7 TCGA Lung Adenocarcinoma 0.0640 0.0238 3.8e-05 0.011 0.028 0.030 NA 0.031 1.7e-02 2.6e-04 1.6e-04 NA 1.4e-04
8 TCGA Stomach Adenocarcinoma 0.1080 0.0400 1.2e-04 0.007 0.075 0.069 NA 0.053 9.7e-02 4.5e-06 1.0e-05 NA 1.0e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.3 1.0 -0.2 -0.2 1.0 0.8 0.5 0.5 -0.3 -0.2
Bipolar Disorder or Schizophrenia 0.1 0.2 0.5 0.5 0.4 -0.2 -0.7 0.3 -0.6 -0.0 0.6
Depressed Affect (Nagel 2018) 0.2 0.4 1.7 1.3 -0.1 0.6 -0.2 -0.2 0.1 -0.2 -0.9
Depression (Nagel 2018) 0.5 0.7 2.4 1.5 0.6 0.8 0.7 1.2 -0.6 0.4 -0.5
Intelligence (Savage-Jansen 2018) 0.4 1.4 7.2 0.5 -0.7 0.0 -2.7 0.6 -0.8 1.2 -0.7
Neuroticism (Nagel 2018) 0.1 0.2 0.6 -0.1 -0.1 0.8 0.6 -0.8 0.4 0.1 0.2
Schizophrenia (2018) 0.4 0.9 2.6 0.9 0.7 -1.1 -1.6 -0.0 -1.1 0.2 1.0
Schizophrenia vs Biploar Disorder 0.9 1.2 5.7 0.0 -0.1 -1.3 -1.4 -0.1 -0.2 0.2 2.4
Worry (Nagel 2018) 0.2 0.5 1.1 -0.7 -1.0 -0.6 0.4 -0.7 0.9 0.4 0.7
Alzheimer’s Disease (in mother) 1.8 2.1 10.2 -3.2 -1.7 -0.9 -0.2 -1.0 0.7 0.5 -1.2
Alzheimer’s Disease (in father) 0.5 0.6 1.4 0.4 1.1 1.2 0.3 -0.7 -0.5 -0.5 0.6
Alzheimer’s Disease (including proxy) 0.5 0.7 2.6 -1.6 -0.3 -0.4 -0.7 -1.4 0.5 -0.0 0.0
Crohns Disease (2017) 0.9 2.0 6.0 0.4 2.5 1.4 0.6 -0.8 -0.3 -2.4 1.0
Irritable Bowel Disease (IBD) 0.4 0.9 3.8 0.2 0.4 -0.1 0.1 0.1 1.0 -1.9 1.4
Ulcerative Colitis (UC) 0.6 1.1 2.9 -0.5 -1.3 -1.0 0.0 0.9 1.7 -0.7 1.2
Major Depression (MDD) 0.8 0.9 3.1 -0.8 1.5 1.7 0.9 -0.5 0.6 0.1 0.1
Reaction Time 0.6 1.1 2.8 -0.2 -0.5 1.0 1.0 0.8 1.7 0.2 1.6
Verbal and Numeric Reasoning (VNR) 0.5 1.3 5.6 1.4 -0.1 0.4 -2.4 0.3 -1.3 0.4 -0.8
Breast Cancer 0.4 0.9 1.9 -1.1 -0.7 -0.1 -1.1 -0.6 1.3 -1.4 0.5
Ovarian Cancer 0.8 1.0 3.3 -0.2 -1.8 0.5 0.5 0.8 0.7 1.5 0.8
Prostate Cancer 0.2 0.3 1.3 1.2 -0.1 0.4 -0.4 0.7 -0.5 -0.1 0.2
Age at First Birth 1.0 1.5 3.8 -0.3 -1.9 -0.7 0.0 1.2 1.4 1.1 1.6
Bipolar Disorder (2011) 0.8 0.8 1.8 -0.2 -1.0 0.2 1.3 1.3 0.8 0.0 -1.1
Body Mass Index (BMI) (2010) 0.2 0.2 0.9 0.5 -0.3 -0.6 0.3 0.4 -0.3 0.2 -0.9
Coronary Artery Disease (CAD) 0.5 0.6 2.0 0.9 0.2 1.0 -0.2 0.0 -1.4 0.5 1.1
Crohns Disease (2012) 0.6 1.0 1.9 1.0 0.9 0.7 -1.1 -1.1 0.5 -1.4 1.2
Mean Putamen Volume 1.2 1.4 3.2 1.7 -1.8 -0.9 0.2 0.6 0.1 1.4 1.2
Fasting Glucose 1.4 1.7 4.8 -0.7 1.5 1.5 2.2 -0.3 -1.4 0.2 -1.2
HbA1C 5.3 5.9 19.8 0.5 4.5 3.0 2.1 1.5 -1.4 -2.6 1.6
HDL Cholesterol 0.5 0.8 1.7 -1.3 1.0 0.9 1.0 0.7 -0.8 0.6 0.9
LDL Cholesterol 0.4 0.7 1.8 0.0 1.3 0.2 0.9 0.0 -0.9 -0.6 -1.3
Lupus 0.5 0.8 2.4 1.1 -0.7 0.1 -0.1 -1.6 0.7 -0.4 -1.2
Neuroticism (2016) 1.8 2.6 11.1 0.1 2.1 3.3 1.4 -0.4 -1.2 -1.3 -0.5
Primary Biliary Cirrhosis 0.9 1.3 5.0 -0.2 0.8 2.2 1.1 0.6 -1.1 -0.9 0.8
Rheumatoid Arthritis 0.4 0.5 1.5 0.5 -1.2 -1.1 -0.3 -0.1 -0.2 0.1 -1.1
Schizophrenia (2014) 0.2 0.5 1.5 0.3 0.4 -0.5 -0.8 0.0 -1.0 0.5 1.2
Triglycerides 0.1 0.2 0.7 -0.4 -0.4 -0.4 -0.2 0.4 -0.3 0.8 -0.4
Type 2 Diabetes (T2D) (2012) 5.1 5.9 25.0 -0.9 1.5 5.0 3.2 1.9 -0.9 1.2 1.7
Ulcerative Colitis 0.5 0.8 2.2 0.6 -0.2 -1.1 -1.5 0.8 0.2 -0.9 1.0
Blood Eosinophil Count 0.3 2.6 5.2 -0.7 2.2 2.3 2.2 -0.7 -0.2 -2.1 0.6
Blood Platelet Count 0.2 2.6 7.6 -1.6 -0.1 -0.7 -0.9 -1.7 1.6 -2.1 -2.8
Blood Red Count 0.7 6.4 27.0 0.9 -5.2 -2.5 -2.8 -0.4 0.5 2.9 -0.8
Blood White Count 0.4 2.8 7.6 -1.0 -0.2 -0.8 -0.9 -2.5 0.0 -2.4 -2.8
Heel T-Score 0.0 0.4 1.3 -0.6 -0.8 -0.2 -0.4 0.7 0.2 1.1 0.4
BMI 0.5 3.0 5.3 -1.6 -2.0 0.7 1.9 -0.5 1.9 2.3 -1.9
Height 0.2 4.7 11.1 1.1 3.3 0.7 -1.1 -3.2 -2.5 -2.7 -0.3
Waist Hip Ratio (WHR) 0.5 2.4 7.0 -1.9 1.2 0.4 -0.2 -2.7 0.8 -1.9 -1.6
Systolic Blood Pressure 0.2 1.2 4.0 0.4 2.0 -0.2 -1.4 -0.3 -1.6 -0.9 0.0
Smoking Status 0.4 0.9 2.3 0.6 0.3 -0.9 0.3 -1.5 -0.9 -1.2 -1.1
Allergy or Eczema 0.3 0.8 2.2 -1.3 1.1 1.5 -0.4 0.1 -0.5 0.0 -0.8
Cardiovascular Disease 0.9 2.8 6.6 -1.3 2.3 1.4 -0.2 -1.7 -1.5 -2.6 -1.4
Hypothyroidism (self reported) 0.4 0.8 3.4 -0.6 -0.8 0.1 -0.5 -0.2 1.2 0.7 1.9
Respiratory disease 0.3 0.7 2.6 0.6 0.4 0.3 0.1 -0.1 -1.6 1.3 -0.6
Type 2 Diabetes (T2D) (2018) 9.1 17.0 59.3 -1.5 1.7 7.7 7.0 2.6 -0.2 2.6 3.1
Lung FEV1/FVC ratio 0.2 0.8 2.3 -0.2 0.2 0.3 1.3 -0.3 1.5 -1.4 -0.5
Lung FVC 0.2 0.9 2.8 0.6 1.7 -0.9 0.0 0.2 -0.7 -1.5 0.3
Neuroticism 0.4 1.0 3.6 -0.4 0.9 -0.0 -0.8 -1.9 0.3 -1.3 -0.8
Chronotype (morning person) 0.4 0.9 3.1 0.7 -0.7 -0.4 0.3 1.1 -0.5 1.8 1.2
Hair Pigment 0.0 1.0 3.3 0.5 1.8 1.2 -0.6 0.1 -0.8 -1.3 0.3
Tanning 0.1 1.6 3.6 -0.6 0.2 1.3 1.1 0.9 -1.5 1.7 1.9
Hand grip strength (left) 0.3 0.7 1.3 -1.1 1.1 0.5 0.5 -0.2 -1.1 -0.7 1.0
Number of treatments/medications taken 0.7 1.2 3.9 -1.1 0.2 1.8 2.0 -0.1 0.4 -0.1 -1.0
Average weekly spirits intake 0.4 0.5 2.1 0.1 -0.1 -0.5 -1.1 -1.4 0.4 0.1 -0.7
Sensitivity / hurt feelings 0.2 0.3 0.9 0.3 0.1 0.9 0.2 -0.7 0.4 -0.6 0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.4 0.7 0.4 0.7 1.1 0.5 0.0 0.4 -1.2
Hearing difficulty/problems: Yes 0.4 0.6 1.5 0.0 1.1 1.2 0.5 -0.5 -0.6 -1.1 -0.3
Relative age of first facial hair 0.3 0.6 1.3 -0.3 1.0 -0.1 0.1 -1.0 1.0 -1.1 -0.6
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 8.1 0.8 -0.2 1.3 -0.4 0.5 0.9 2.9 0.8
Ever used hormone-replacement therapy (HRT) 2.2 2.8 11.2 -0.9 -0.6 1.8 3.4 1.3 1.6 1.5 0.6
Ever had hysterectomy (womb removed) 0.8 0.9 2.0 -0.2 0.9 1.4 1.3 0.8 0.3 -0.7 -1.1
Systolic blood pressure, automated reading 0.5 1.4 3.1 1.0 1.8 0.1 -1.5 -1.2 -1.6 -0.6 -0.7
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 4.7 -0.8 -0.8 1.3 2.2 1.5 0.9 1.0 0.1
Angina 0.7 0.9 1.7 -0.4 -1.0 -0.5 -0.8 -0.6 1.3 -1.3 -1.1
Medication for hormone replacement therapy 1.5 1.7 3.7 -0.3 -0.3 1.6 1.9 1.3 0.6 1.7 1.5
Vitamin and mineral supplements 1.0 1.4 5.3 -0.8 0.6 -0.7 0.1 -0.8 -1.1 -1.6 -2.3
Supplements: Zinc 1.6 1.8 4.8 -1.0 0.7 -1.1 -2.2 -1.4 1.1 -1.8 -0.2
Medication: Co-codamol 0.5 0.6 1.7 1.3 0.1 0.4 1.2 -0.2 -0.6 -0.4 1.0
Medication: Metformin 3.3 4.7 18.1 -1.1 2.1 3.4 4.3 0.1 0.2 0.3 1.6
Diabetes (father) 4.9 6.1 18.8 -0.3 -0.7 3.5 4.3 2.0 0.6 3.1 1.9
Diabetes (mother) 3.6 4.6 16.4 -0.6 1.2 4.0 2.9 1.8 -0.1 1.2 2.3
Severe depression (siblings) 0.4 0.5 2.0 -0.1 -0.3 0.2 -0.9 0.3 1.4 0.3 0.9
Pack years adult smoking proportion 0.3 0.5 1.0 -0.2 -0.8 -0.9 -0.8 -0.0 1.0 -0.2 -0.6
Impedance of leg (right) 0.5 2.5 10.3 0.5 1.2 -1.2 -2.0 -0.5 -1.3 -3.2 0.7
Leg fat-free mass (left) 0.3 1.4 2.7 -0.6 -1.6 0.1 0.4 -1.2 1.5 1.6 -1.4
Trunk fat percentage 0.2 0.8 2.8 0.6 0.2 1.7 0.3 -0.9 0.1 0.4 -1.5
Hand grip strength (right) 0.3 0.9 2.7 0.4 1.6 0.4 0.0 -0.8 -1.5 -1.1 -0.2
Townsend deprivation index at recruitment 0.3 0.4 1.2 -0.8 -0.6 -0.3 1.1 0.3 0.7 -0.1 -0.3
Current tobacco smoking 0.7 1.2 4.5 2.1 -0.2 -1.0 -0.6 -0.9 -0.5 -1.2 -0.9
Average weekly fortified wine intake 0.3 0.4 2.2 -0.0 -0.5 0.4 -0.4 -0.0 1.5 0.5 -0.1
Maternal smoking around birth 1.0 1.4 2.4 -1.5 -0.8 1.4 1.0 1.1 1.5 0.9 1.0
Fed-up feelings 0.4 0.7 3.2 0.3 0.0 1.8 0.9 -0.4 0.9 0.6 -0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.5 0.3 0.1 1.1 0.8 1.2 -0.7 0.7 -1.1
Relative age voice broke 0.4 0.6 2.2 -0.8 0.2 -0.2 0.2 -0.8 1.5 -0.9 -0.3
Taking other prescription medications 0.5 0.8 2.2 -1.1 -0.8 1.0 1.5 -0.6 0.7 0.4 -0.3
Age when periods started (menarche) 0.5 1.2 4.1 -0.9 1.3 1.1 2.0 -0.3 -0.3 -0.4 1.0
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 1.3 -0.6 0.6 1.2 0.9 0.9 0.4 -0.7 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 4.3 -1.0 -1.4 -0.3 -1.7 1.4 2.1 0.6 0.7
Tinnitus: Yes, but not now, but have in the past 2.3 2.4 5.2 -1.9 -1.1 2.3 1.1 1.1 1.5 1.4 1.6
Qualifications: CSEs or equivalent 1.6 2.1 6.4 0.2 0.1 -2.5 -1.2 -1.5 -1.3 -1.2 -1.9
Serious illness, injury or assault to yourself 2.5 3.0 5.9 -1.6 -1.1 1.3 0.2 2.0 2.4 2.4 1.7
High blood pressure 1.0 2.8 7.0 -0.5 2.0 1.3 -0.3 -1.3 -1.1 -2.6 -2.4
Hayfever, allergic rhinitis or eczema 0.4 0.9 2.7 -0.9 1.6 1.6 -0.5 0.2 -1.1 0.1 0.3
Multivitamins +/- minerals 0.6 0.7 1.8 -0.2 -0.9 0.9 0.9 0.1 0.8 1.3 0.9
Stomach or abdominal pain in last month 0.4 0.5 1.7 -0.6 -0.7 0.6 -0.4 -0.9 1.3 0.3 0.6
Supplements: Glucosamine 0.9 1.2 5.2 -0.7 0.4 1.5 2.3 0.5 -0.5 0.1 0.9
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.2 -0.6 0.2 -0.1 -0.3 -0.5 0.3 -0.1 -1.1
Medication: Atenolol 0.2 0.3 1.1 -0.5 -1.1 -0.8 -0.3 0.0 0.4 -0.4 -0.1
Medication: Levothyroxine sodium 0.9 1.5 4.8 -1.4 -2.2 -0.3 -0.2 -0.0 1.8 1.3 0.5
Sitting height 0.3 2.3 4.5 0.8 1.0 -1.6 -2.0 -2.1 -0.6 -2.0 -0.9
Chronic bronchitis/emphysema (father) 1.4 1.6 4.2 -0.1 -0.6 -1.5 -2.1 -1.3 -0.4 -1.6 -1.3
High blood pressure (mother) 0.7 1.0 2.1 -0.4 1.3 0.4 -1.4 -1.0 -0.9 -1.5 0.5
Body mass index (BMI) 0.4 1.6 3.0 -0.7 -1.2 1.2 1.5 -0.9 1.2 1.5 -1.7
Impedance of leg (left) 0.5 2.3 8.5 1.1 1.4 -1.0 -1.6 -0.3 -1.4 -2.9 1.1
Leg predicted mass (left) 0.3 1.4 2.5 -0.6 -1.6 0.0 0.4 -1.3 1.4 1.5 -1.5
Trunk fat mass 0.2 0.9 2.7 0.1 -0.5 1.6 0.6 -1.0 0.5 0.8 -1.5
Waist circumference 0.6 2.0 4.6 -1.5 -0.9 0.7 0.4 -2.1 1.8 0.6 -2.1
Number of incorrect matches in round 0.6 0.9 2.8 -0.3 0.9 1.3 0.2 1.3 0.7 -0.4 1.7
Past tobacco smoking 0.1 0.2 0.6 0.3 -0.2 -0.5 -0.8 0.2 0.6 0.2 0.5
Alcohol usually taken with meals 2.4 4.0 13.8 -0.8 -0.8 2.7 1.0 3.7 -0.7 2.4 1.6
Nervous feelings 0.7 1.4 2.6 -0.8 -1.0 0.5 1.6 0.6 1.1 1.4 1.6
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.7 -0.4 -0.3 0.6 0.3 1.3 0.8 0.5 0.0
Hearing difficulty/problems with background noise 0.7 1.1 5.9 -0.7 0.5 2.4 0.6 0.5 -1.2 -0.3 -0.2
Hair/balding pattern: Pattern 2 1.3 1.7 6.5 -0.0 -1.6 -2.5 -1.0 -1.1 1.5 -0.2 -0.4
Had menopause 0.4 0.4 1.4 -0.1 0.8 0.7 0.3 -0.7 0.3 -1.2 -0.5
Had other major operations 0.9 1.0 4.2 0.5 1.1 1.5 0.1 0.2 -0.3 -0.4 2.1
Forced vital capacity (FVC) 0.7 2.7 8.1 -0.1 2.2 -1.8 -0.9 -1.5 -1.4 -2.8 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.0 3.8 -0.3 -0.1 0.5 -1.7 2.0 0.7 0.5 0.8
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.3 -0.9 1.1 -0.9 -1.0 -0.1 -0.4 0.3 0.0
Qualifications: None of the above 0.8 1.7 6.6 0.4 0.7 -1.1 0.3 -1.6 0.6 -2.6 -1.5
Financial difficulties in last 2 years 0.4 0.5 1.4 0.2 1.2 -0.6 -0.9 0.4 0.2 -0.7 0.9
Mouth/teeth dental problems 0.7 1.0 2.9 0.7 -0.7 0.9 -0.0 1.0 -0.8 1.4 1.7
Heart attack 0.8 1.0 4.3 0.0 1.5 0.8 -0.1 -0.5 0.5 -2.1 0.1
Allergy 0.7 1.6 5.4 0.7 -2.3 -2.1 -0.2 0.1 1.4 0.1 -0.2
Pain all over the body in last month 2.0 2.2 10.6 3.2 -0.3 -0.2 -2.2 0.9 -0.0 0.9 -0.5
Diabetes (self-reported) 7.9 12.2 40.6 -1.0 1.6 6.4 6.3 2.1 -0.2 2.1 2.2
Hayfever/allergic rhinitis (self-reported) 0.7 1.0 3.1 -0.5 0.3 1.4 0.0 1.8 -0.6 1.3 0.4
Medication: Ramipril 1.3 1.6 4.5 1.1 2.1 0.3 -0.3 -0.7 -1.3 -2.1 -0.7
Medication: Simvastatin 0.8 1.1 2.6 -1.0 0.3 1.5 0.6 -0.8 -0.8 -1.2 -1.6
Fluid intelligence score 0.7 1.5 8.6 0.8 -0.5 0.2 -2.9 0.7 -0.1 1.2 -0.2
Illnesses of siblings 0.5 0.7 2.0 1.2 -0.3 -0.6 -0.2 0.1 1.0 1.4 0.8
Neuroticism score 0.1 0.3 1.3 -0.2 -0.0 0.3 0.5 -0.8 1.1 -0.3 0.1
Weight 0.3 1.3 2.3 -0.7 -1.1 0.8 0.6 -1.4 1.3 1.1 -1.5
Impedance of arm (right) 0.4 2.0 4.7 1.3 1.6 1.0 -1.7 0.7 -1.6 -2.2 0.3
Arm fat percentage (right) 0.3 1.1 4.8 0.2 -0.6 2.2 0.7 -0.0 0.4 1.0 -1.5
Trunk fat-free mass 0.3 1.5 2.9 -1.6 -1.7 -0.4 0.5 -1.3 1.6 1.4 -0.0
Hip circumference 0.3 1.2 2.6 -0.0 -1.4 0.5 0.1 -1.2 1.6 1.0 -1.6
Time employed in main current job 2.2 2.5 5.8 -1.1 -0.2 1.7 2.4 1.8 1.5 1.4 1.5
Alcohol intake versus 10 years previously 0.3 0.5 2.2 -0.6 -0.9 0.4 1.5 -0.0 0.2 0.3 -0.7
Father’s age at death 0.9 1.1 4.5 0.8 0.0 0.6 0.7 2.1 -0.3 0.8 1.5
Worrier / anxious feelings 0.2 0.3 0.8 -0.9 -0.5 0.6 0.8 0.1 0.7 0.1 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 3.6 0.8 -1.0 1.0 -0.2 1.2 0.8 1.9 -0.2
Falls in the last year 0.2 0.2 0.7 -0.1 0.5 -0.4 -0.1 -0.0 -0.8 -0.5 -0.6
Hair/balding pattern: Pattern 3 0.6 0.9 2.0 -1.1 1.4 0.1 1.3 0.1 -0.4 -0.2 1.3
Number of live births 0.4 0.6 1.8 -0.4 0.5 1.2 0.7 -1.3 0.5 -0.6 -0.4
Forced expiratory volume in 1-second (FEV1) 0.9 3.0 12.1 0.0 2.2 -1.8 -1.1 -1.7 -0.3 -3.5 -0.2
Pulse rate 0.2 0.3 0.6 -0.5 -0.5 -0.1 -0.7 -0.8 0.5 -0.6 -0.4
Happiness 0.8 1.0 4.8 -1.1 0.4 0.1 2.2 -0.1 -0.3 0.5 -1.1
Noisy workplace 0.4 0.5 1.3 -1.1 0.4 -0.1 0.9 -0.8 0.4 -0.8 -0.1
Qualifications: A levels/AS levels or equivalent 1.4 3.1 9.9 1.0 -0.4 -0.2 -1.0 2.0 -1.6 3.1 2.5
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.9 -0.8 0.1 1.4 0.4 -0.7 0.3 -0.1 0.6
Mouth/teeth dental problems: Dentures 0.6 1.0 2.9 -0.7 0.4 -0.1 1.4 -1.0 0.0 -1.0 -1.7
Asthma 0.4 0.8 3.5 0.5 1.4 0.6 -0.0 0.1 -1.9 0.6 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.2 1.7 1.2 1.3 1.3 -0.6 1.3 0.6 -0.5 1.3
Medication: Cholesterol lowering 1.4 2.2 4.6 -1.4 0.9 2.0 0.7 -0.7 -1.2 -1.9 -2.2
Depression (self-reported) 1.0 1.3 3.6 -0.7 -1.7 0.9 1.2 0.0 0.6 0.7 -1.9
Medication: Lansoprazole 0.8 0.9 3.3 1.7 -0.2 -0.1 -0.3 -0.7 0.1 0.8 -1.8
Prospective memory result 1.3 1.6 4.4 -1.2 1.0 1.6 2.1 0.3 0.6 0.6 1.4
Lung cancer (father) 0.9 1.0 2.2 -0.7 0.0 -1.4 -1.3 -1.5 0.8 -1.0 0.1
Illnesses of mother 1.4 1.7 4.9 -0.2 -2.2 -1.9 -0.9 0.5 1.3 1.3 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.6 6.5 -0.5 1.1 -1.8 -0.9 -0.9 0.4 -2.6 0.0
Pulse wave Arterial Stiffness index 1.2 1.4 2.6 -0.0 -1.6 1.0 1.4 1.4 1.0 1.6 0.2
Impedance of arm (left) 0.5 2.2 4.3 1.3 1.9 1.4 -1.6 0.7 -1.6 -2.1 0.1
Arm fat mass (right) 0.3 1.3 3.7 -0.4 -1.1 1.4 0.8 -0.9 0.8 1.0 -1.9
Trunk predicted mass 0.3 1.5 2.9 -1.5 -1.7 -0.4 0.5 -1.2 1.6 1.5 0.0
Standing height 0.1 0.7 2.1 -0.3 -0.0 -0.3 -1.4 -1.5 0.4 -0.9 0.2
Length of working week for main job 0.6 0.6 1.5 -0.6 -1.2 -0.5 0.2 -0.6 1.1 0.2 -1.1
Exposure to tobacco smoke at home 1.0 1.1 2.8 -0.4 0.0 -1.4 -0.6 -1.7 -0.3 -1.4 -1.4
Breastfed as a baby 1.2 1.5 3.2 1.2 1.4 -1.1 0.4 -0.9 -1.5 -0.8 -1.8
Tense / ‘highly strung’ 0.6 1.0 2.9 -1.7 -1.2 0.0 0.6 -0.9 1.2 0.6 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.0 0.2 0.6 0.0 -0.6 0.4 -0.7 -0.9 -1.0
Hair/balding pattern: Pattern 4 0.6 1.4 5.3 2.3 -0.7 0.8 -0.7 -0.0 -1.7 0.1 -1.2
Birth weight of first child 1.2 2.1 11.2 0.7 0.5 3.4 1.9 0.8 -0.1 -0.4 0.8
Peak expiratory flow (PEF) 0.9 2.1 7.1 -0.7 2.3 0.2 -1.1 -0.8 -1.0 -2.7 -1.0
Pulse wave reflection index 3.6 4.5 12.6 0.1 -1.3 1.4 2.9 3.5 0.8 2.9 1.4
Ever highly irritable/argumentative for 2 days 0.8 0.9 2.0 -1.2 -0.4 -1.4 -0.8 -1.2 1.1 -0.3 -0.7
Loud music exposure frequency 0.6 0.6 1.9 -0.3 0.3 0.5 0.4 0.3 1.2 -1.4 1.1
Qualifications: O levels/GCSEs or equivalent 1.7 2.7 7.5 1.5 0.7 0.3 -0.8 2.7 -1.3 1.8 2.4
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.2 -0.0 1.1 0.4 -0.8 -0.9 0.4 -1.5 -1.3
Blood clot in the leg (DVT) 0.4 0.5 1.2 -0.5 -0.0 1.1 1.0 -0.5 0.9 -0.4 -0.4
Medication: Paracetamol 0.7 1.1 2.4 0.8 -0.3 -0.2 -1.2 0.4 1.5 -1.6 -1.4
Headache pain in last month 1.1 1.8 4.2 -1.2 0.4 -0.5 0.0 -1.9 1.6 -2.1 -1.7
Medication for cholesterol, blood pressure or diabetes 0.9 1.6 2.9 1.2 -0.9 -1.7 -1.1 0.5 1.2 1.3 1.6
Glaucoma (self-reported) 0.5 0.6 1.3 -0.8 -0.7 0.0 0.4 1.1 -0.3 1.1 0.9
Gout (self-reported) 0.7 1.0 1.7 1.3 -1.1 0.6 -0.9 0.8 -1.3 0.5 -1.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.2 -0.5 -0.6 0.2 -0.1 -0.7 0.7 0.6 1.5
Medication: Amlodipine 1.1 1.5 4.5 -2.1 0.5 2.1 1.2 -0.7 -0.1 0.4 -0.8
Medication: Ventolin 100micrograms inhaler 1.8 2.4 6.1 -0.1 -0.9 1.3 0.9 1.8 0.9 2.3 2.5
Birth weight 4.4 9.5 33.3 1.1 2.0 5.8 4.5 1.6 -2.3 2.3 2.0
Chronic bronchitis/emphysema (mother) 1.7 1.9 6.7 0.3 2.6 1.1 -0.2 -1.7 -1.3 -1.6 -0.4
High blood pressure (siblings) 0.4 0.6 1.6 -1.3 1.0 0.4 -0.1 -0.6 -1.0 -0.9 -0.2
Forced vital capacity (FVC), Best measure 0.4 1.5 4.6 -0.4 1.4 -1.5 -1.1 -1.0 -0.6 -2.1 0.4
Body fat percentage 0.2 0.8 2.9 0.3 -0.2 1.7 0.7 -0.7 0.3 0.4 -1.5
Leg fat percentage (right) 0.3 1.2 2.8 -0.6 -1.3 0.9 1.3 -0.7 1.2 0.4 -1.7
Arm fat-free mass (right) 0.3 1.5 3.2 -0.9 -1.8 -0.7 0.7 -1.5 1.6 1.5 -0.2
Exposure to tobacco smoke outside home 0.7 1.0 3.2 -1.5 0.2 -0.1 0.9 -1.3 1.8 0.4 0.1
Comparative body size at age 10 3.0 8.3 16.2 0.2 -4.0 1.9 1.1 2.4 3.0 4.0 3.7
Number of full brothers 1.2 1.6 4.2 -1.4 0.2 0.9 2.1 -0.5 -0.6 -1.5 -1.6
Worry too long after embarrassment 0.3 0.5 1.0 -0.8 0.9 0.1 0.1 -0.8 -0.0 -1.0 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 1.9 -1.2 -0.5 0.6 -1.4 0.6 0.1 -0.1 -0.9
Wheeze or whistling in the chest in last year 0.1 0.2 0.4 0.4 -0.1 0.6 0.4 -0.5 0.7 0.7 -0.0
Number of children fathered 0.5 0.6 2.5 -0.7 -0.7 1.6 0.9 -0.1 0.2 0.4 0.2
Reason for reducing amount of alcohol drunk: Health precaution 4.2 5.0 18.7 0.2 2.7 3.4 -0.3 0.5 -4.3 -1.1 -0.6
Age at first live birth 0.4 0.8 1.9 -0.8 0.2 -1.1 -1.4 0.1 1.2 0.5 1.0
Pulse wave peak to peak time 1.1 1.3 2.8 0.0 1.6 -0.8 -1.3 -1.4 -1.0 -1.7 -0.2
Health satisfaction 0.3 0.4 1.8 -0.9 -0.6 0.6 0.0 0.0 0.0 1.3 -0.4
Shortness of breath walking on level ground 0.3 0.4 1.4 -0.0 0.0 0.5 -0.4 0.4 -1.2 0.4 1.1
Qualifications: College or University degree 0.9 2.7 9.6 -0.4 -1.0 0.1 -0.7 2.7 0.2 3.1 1.8
Eye problems/disorders: None of the above 0.8 0.9 3.4 1.3 -0.3 -1.3 -0.0 -0.4 1.8 0.3 0.5
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.2 0.8 0.2 -0.4 -1.1 -0.1 -1.0 1.1 -0.6
Emphysema/chronic bronchitis 1.0 1.1 3.8 1.3 -0.6 1.9 0.8 1.1 0.8 0.5 0.5
Medication for pain relief, constipation, heartburn 1.0 1.8 5.5 -0.3 0.0 -0.1 1.2 0.8 -2.0 2.4 1.5
Neck or shoulder pain in last month 0.5 0.7 2.5 -0.4 -0.1 -1.6 0.2 -0.9 0.7 -1.2 -0.8
Medication: Blood pressure 0.6 1.1 3.3 -0.1 1.2 1.0 0.2 -0.4 -1.4 -1.8 -1.1
Angina (self-reported) 0.5 0.7 1.7 -0.3 -0.9 -0.4 -0.9 -0.3 1.3 -1.2 -0.7
Migraine (self-reported) 0.7 0.9 3.6 -1.0 0.8 -0.3 0.3 -1.9 0.6 -1.3 0.0
Medication: Ibuprofen 0.6 0.7 1.5 0.7 1.1 1.0 0.0 1.2 0.7 -0.3 1.0
Medication: Allopurinol 1.3 1.8 3.3 1.8 -1.8 -0.5 -1.5 0.8 -1.3 0.8 -1.4
Medication: Omeprazole 1.4 1.7 6.2 -2.3 -1.5 -0.3 0.0 0.2 2.5 0.2 0.1
Medication: Seretide 50 evohaler 0.6 0.7 2.2 -0.4 -0.6 1.5 -1.1 0.4 1.2 -0.5 0.5
Mean time to correctly identify matches 0.6 1.2 2.3 0.3 -0.0 1.2 1.2 1.3 1.4 0.2 1.5
Heart disease (mother) 0.7 0.9 2.0 1.2 0.1 -0.4 -0.3 -1.4 -0.7 -1.2 -1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.6 0.9 0.7 0.6 1.3 -0.3 -0.6 -0.3 -0.6
Whole body fat mass 0.2 0.9 3.0 0.0 -0.7 1.3 0.7 -1.2 0.5 0.5 -1.7
Leg fat mass (right) 0.3 1.3 3.8 -0.2 -1.4 0.8 1.0 -1.3 1.0 0.5 -1.9
Arm predicted mass (right) 0.3 1.6 3.5 -1.1 -1.9 -0.8 0.6 -1.6 1.4 1.6 -0.2
Pulse rate, automated reading 0.3 0.8 3.2 -1.0 -1.8 -1.1 -0.3 -0.2 1.0 0.3 -0.0
Alcohol intake frequency. 1.2 2.8 8.6 -1.5 -2.9 -1.0 1.7 -1.7 1.2 1.0 -1.6
Comparative height size at age 10 0.0 0.2 1.0 -0.4 -0.5 0.1 -1.0 -0.5 -0.1 0.0 0.2
Number of full sisters 0.7 0.8 2.6 -0.2 -0.6 -0.9 -0.7 -0.8 0.1 -1.2 -1.6
Suffer from ‘nerves’ 1.6 2.5 5.6 -1.4 -1.5 -0.3 2.0 0.4 2.2 1.1 2.4
Overall health rating 0.3 0.5 1.3 0.4 -1.0 -0.1 -0.2 -0.6 1.0 0.7 -1.1
Chest pain or discomfort 0.7 1.0 3.2 0.0 -0.9 -1.0 -0.5 1.1 1.2 1.8 0.6
Had major operations 0.9 1.1 3.1 -0.1 1.8 1.0 0.8 0.4 -1.7 -0.5 0.8
Age at last live birth 0.5 0.7 2.5 0.0 0.1 -1.6 -1.4 -0.6 0.8 0.1 -0.5
Family relationship satisfaction 1.3 1.6 7.3 -2.7 -0.6 -0.1 1.2 0.1 1.6 0.5 -0.8
Leg pain on walking 0.4 0.5 1.3 -1.1 0.8 0.6 0.4 -0.1 -0.6 -1.0 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 3.1 -0.3 -0.8 -0.8 -1.1 -1.5 0.2 -0.8 -1.8
Commuting to job workplace: Car/motor vehicle 0.9 1.1 3.0 -0.8 -1.7 -1.2 -1.2 0.3 0.3 1.0 -0.9
Illness, injury, bereavement, stress in last 2 years 0.1 0.2 0.5 0.6 -0.1 -0.7 0.1 -0.3 -0.4 -0.1 -0.3
Medication: Aspirin 2.5 3.3 12.6 0.1 2.1 -0.1 -1.8 -1.8 -1.0 -3.6 -1.5
Supplements: Vitamin C 2.4 2.9 11.3 1.4 1.0 0.3 -2.2 1.2 1.3 0.6 3.4
Knee pain experienced in last month 2.9 4.5 11.3 -2.3 2.9 1.6 0.2 -2.0 0.2 -3.4 -1.9
Hypertension (Self-reported) 1.0 2.7 5.9 -0.5 2.4 1.3 -0.1 -1.3 -1.5 -2.4 -2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 3.6 0.5 -1.7 0.1 1.9 1.1 0.8 0.8 -0.5
Illnesses of father: Heart disease 1.2 1.7 5.3 1.4 1.5 2.3 0.5 0.9 -0.8 -0.8 1.1
Illnesses of siblings: Diabetes 2.0 2.4 9.2 -1.7 1.3 3.0 1.9 -0.5 -0.9 -0.9 -0.2
Smoking status: Previous 0.3 0.5 1.4 -1.0 -0.1 0.7 0.7 -0.4 -0.2 0.1 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 3.2 0.0 -0.6 -1.4 -1.8 0.2 0.9 -0.1 -0.1
Whole body fat-free mass 0.3 1.5 3.2 -1.0 -1.8 -0.3 0.6 -1.3 1.7 1.6 -0.5
Leg fat-free mass (right) 0.3 1.5 3.7 -0.4 -1.6 0.3 0.6 -1.1 1.5 1.9 -1.3
Arm fat percentage (left) 0.3 1.2 5.0 0.2 -0.5 2.2 0.8 -0.0 0.4 1.1 -1.5
Average weekly red wine intake 0.4 0.6 2.5 0.1 -0.4 -0.4 -0.6 1.6 0.0 0.7 0.9
Handedness (chirality/laterality): Left-handed 0.7 0.8 4.3 0.0 -1.1 -2.1 -0.6 -0.2 0.4 0.6 0.1
Mood swings 0.3 0.6 1.9 0.1 -0.5 1.3 -0.5 0.6 1.4 0.3 0.4
Loneliness, isolation 0.4 0.6 1.8 0.9 0.4 0.8 1.3 0.4 -0.8 -0.0 -0.7
Long-standing illness, disability or infirmity 0.9 1.4 7.9 -0.2 0.7 2.8 1.7 -0.3 0.0 0.3 0.1
Ever had bowel cancer screening 1.5 1.8 3.8 1.7 0.9 1.8 1.0 1.5 -0.1 0.5 2.0
Diabetes diagnosed by doctor 6.5 10.7 39.2 -1.2 1.6 6.3 5.8 1.6 -0.1 1.6 2.1
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.3 0.8 0.1 0.7 -0.2 -0.2 -0.2 -0.9 0.5 0.6
Friendships satisfaction 0.9 1.1 3.3 -1.5 -0.9 -0.1 1.0 -0.5 1.8 0.8 -0.8
Qualifications: nursing, teaching 1.4 2.2 6.2 1.3 -1.1 0.5 -1.4 2.5 -0.3 2.2 1.3
Commuting to job workplace: Walk 0.2 0.2 0.6 0.3 0.5 -0.2 0.1 -0.8 -0.0 -0.5 -0.2
Eye problems/disorders: Cataract 0.9 1.0 3.0 -1.2 0.5 0.4 0.0 -0.3 -1.6 -0.8 -1.7
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 3.7 -0.7 -0.8 -0.3 0.6 -0.0 1.9 -0.5 0.5
Medication for cholesterol 0.4 0.6 2.8 0.4 -1.1 -0.3 -1.7 0.2 0.5 0.3 -0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 3.7 -0.8 -0.7 0.3 0.3 -0.4 1.9 -0.8 -1.3
Back pain experienced in last month 0.9 1.3 5.6 -0.7 -0.3 -0.6 -0.5 -0.6 0.5 -1.7 -2.4
Mineral and other dietary supplements 0.2 0.2 0.9 -0.0 -0.4 -0.6 -0.3 0.1 -0.3 0.3 -0.9
Breast cancer (self-reported) 1.3 1.6 4.2 1.1 -0.8 1.2 0.6 1.9 -0.1 2.0 1.2
Asthma (self-reported) 0.5 0.9 3.7 0.7 1.2 0.7 0.1 0.2 -1.9 1.1 -0.1
Osteoporosis (self-reported) 0.9 1.1 2.3 0.8 1.4 1.5 0.4 -0.8 -1.5 -0.8 -0.0
Osteoarthritis (self-reported) 0.2 0.3 1.7 -0.5 0.3 0.1 -0.4 -0.0 -1.3 0.0 0.3
Medication: Aspirin 2.8 3.7 14.2 0.3 2.2 -0.2 -1.7 -1.5 -1.5 -3.8 -1.5
Medication: Gliclazide 1.3 1.5 6.1 0.2 -0.5 2.5 1.8 1.0 0.7 0.8 0.5
Illnesses of father: None of the above (group 1) 3.3 4.1 10.3 -1.2 -2.4 -3.2 -2.4 0.2 3.0 0.8 0.2
Smoking status: Current 0.7 1.1 4.4 2.1 -0.2 -0.6 -0.1 -0.8 -0.6 -1.3 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.1 0.5 -0.1 -0.2 -0.7 0.0 -0.0 0.1 -0.6 0.4
Whole body water mass 0.2 1.4 2.6 -1.1 -1.6 -0.2 0.6 -1.3 1.6 1.6 -0.6
Leg predicted mass (right) 0.3 1.5 3.7 -0.4 -1.6 0.3 0.7 -1.1 1.6 1.9 -1.2
Arm fat mass (left) 0.3 1.1 3.0 -0.4 -0.9 1.4 0.6 -0.8 0.6 1.0 -1.7
Number of self-reported non-cancer illnesses 0.3 0.6 1.3 0.1 0.2 0.8 0.6 -1.0 -1.2 -0.1 -1.1
Average weekly champagne plus white wine intake 1.3 1.7 5.0 -2.2 1.0 1.7 0.8 1.2 -0.3 0.7 1.5
Miserableness 1.2 2.2 7.0 -0.6 -2.6 0.2 0.2 0.7 2.6 1.1 -1.1
Guilty feelings 0.7 1.0 3.5 1.5 1.2 0.3 0.5 -0.6 -1.9 -0.0 0.2
Wears glasses or contact lenses 1.6 1.8 4.3 0.9 1.5 -0.4 -0.4 -1.0 -1.4 -2.1 -1.9
Ever taken oral contraceptive pill 0.7 0.7 2.4 -1.6 -0.7 -0.2 0.6 0.2 1.3 0.4 0.8
Hearing aid user 0.8 0.9 2.2 -1.5 -0.2 1.4 1.1 -0.4 0.8 0.1 0.8
Mother’s age at death 0.7 0.9 2.8 -0.7 0.7 1.3 1.7 -0.1 -0.2 -1.1 -0.8
Financial situation satisfaction 0.4 0.5 1.0 -0.4 -0.2 -0.4 1.0 -0.2 1.0 0.8 -1.0
Tinnitus: Yes, now most or all of the time 1.5 1.7 5.4 -0.0 1.9 1.1 1.1 0.1 -2.3 -1.4 0.5
Commuting to job workplace: Public transport 0.3 0.4 0.8 0.7 -0.5 -0.7 -0.7 -0.5 0.9 0.7 0.0
Eye problems/disorders: Glaucoma 0.2 0.3 0.8 0.2 0.2 -0.6 -0.8 0.3 -0.9 -0.6 -0.0
Medication: Blood pressure 0.8 1.6 4.3 0.9 2.1 1.2 1.2 -0.5 -1.3 -1.4 -0.7
Pain type(s) experienced in last month: Hip pain 0.6 0.8 2.8 -1.7 0.1 0.6 0.4 -0.2 0.5 -1.0 -1.3
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.3 0.8 -0.6 1.0 0.2 0.4 0.3 0.6 1.1
High cholesterol (Self-reported) 1.6 2.9 5.9 -1.6 2.4 1.7 1.1 -1.7 -1.1 -2.0 -1.4
Medication: Bendroflumethiazide 1.7 2.6 6.4 -0.0 1.9 0.1 0.5 -1.8 -1.3 -2.4 -2.5
Medication: Paracetamol 1.4 2.1 3.9 0.9 -0.8 -0.8 -1.9 -0.2 1.9 -2.0 -1.9
Medication: Lisinopril 0.5 0.6 1.8 -0.9 0.3 -1.3 -0.5 -1.1 0.1 -0.2 -0.8
Medication: Atorvastatin 1.5 1.9 4.5 -1.6 1.3 1.4 1.3 -0.5 -0.2 -2.1 -1.7
Illnesses of father: High blood pressure 0.5 0.6 1.2 0.2 0.9 0.8 0.7 0.3 -1.1 -0.3 -1.0
Alcohol drinker status: Never 1.1 1.3 4.2 -0.1 -1.5 -0.9 2.0 -0.5 -0.0 1.7 0.1
Ever smoked 0.2 0.3 0.6 -0.6 -0.3 -0.3 0.8 -0.3 0.6 -0.1 -0.7
Basal metabolic rate 0.2 1.4 2.6 -1.0 -1.6 -0.1 0.4 -1.4 1.5 1.5 -0.9
Leg fat percentage (left) 0.3 1.0 2.0 -0.2 -1.0 1.2 1.4 -0.5 1.0 0.6 -1.4
Arm fat-free mass (left) 0.3 1.7 3.4 -1.3 -1.8 -0.8 0.4 -1.8 1.4 1.2 -0.8
Number of operations (self-reported) 1.1 1.7 3.9 -0.1 1.2 1.8 2.0 1.0 -0.4 -0.2 1.8
Average weekly beer plus cider intake 0.3 0.4 1.1 0.2 -0.9 -0.8 0.6 -0.3 1.0 0.7 -0.0
Irritability 0.8 1.3 3.1 -1.5 -0.3 -0.5 -0.7 -1.8 1.0 -0.4 -1.8
Risk taking 0.9 1.3 4.1 2.0 -0.4 -1.6 -0.4 0.9 -0.4 1.6 0.1
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.5 0.5 0.3 0.7 0.2 -0.3 0.6 -0.6 0.1
Fractured/broken bones in last 5 years 0.6 0.7 3.5 -1.9 0.8 0.6 -0.1 0.0 -0.3 -1.1 0.0
Age started oral contraceptive pill 1.2 1.5 4.0 0.2 0.8 2.0 1.8 0.9 -1.3 0.8 0.7
Diastolic blood pressure, automated reading 1.0 3.2 7.7 0.9 2.8 -0.1 -1.9 -2.2 -2.1 -1.8 -1.0
Ever depressed for a whole week 0.3 0.4 1.9 -0.4 0.8 -0.1 -0.3 0.6 -1.4 0.6 -0.0
Unable to work because of sickness or disability 0.7 0.9 5.2 0.6 0.0 2.3 1.0 0.8 -0.3 -0.1 0.3
Commuting to job workplace: Cycle 0.7 0.9 1.6 -0.4 1.3 -0.4 -0.4 -0.8 -1.2 -1.2 -1.2
Myopia 0.8 1.2 3.9 0.1 -0.2 0.2 1.1 0.8 0.9 1.7 2.0
Vascular/heart problems diagnosed by doctor 1.3 3.5 11.2 0.6 -2.1 -1.0 0.4 1.2 1.0 3.3 2.8
Cholesterol lowering medication 0.8 1.1 2.1 -1.2 1.0 1.1 1.4 -0.9 -0.5 -1.4 -0.2
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 4.0 -1.1 -1.3 -0.6 0.0 0.2 2.0 0.4 -0.4
Pain experienced in last month 2.2 3.7 7.4 1.3 -0.5 1.7 0.5 2.7 -1.7 2.7 2.7
Supplements: Calcium 0.5 0.6 2.1 0.3 0.9 0.1 1.0 0.4 -0.2 0.6 1.5
Basal cell carcinoma (self-reported) 0.2 0.2 0.6 -0.1 -0.3 -0.7 0.0 -0.8 0.5 -0.2 0.1
Heart attack/myocardial infarction (self-reported) 0.7 0.9 3.1 -0.1 1.6 1.2 0.1 -0.0 0.5 -1.8 0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 1.5 -0.6 -0.2 1.2 1.1 -0.5 0.9 -0.1 -0.5
Heart disease (siblings) 0.2 0.2 0.4 -0.4 -0.0 0.6 0.1 0.3 -0.4 -0.6 -0.6
Alcohol drinker status: Previous 0.7 0.8 3.3 0.2 1.4 0.6 0.2 0.2 -1.8 -0.7 0.7
Pack years of smoking 0.1 0.2 0.6 -0.2 -0.3 -0.3 -0.5 0.1 0.6 -0.5 -0.7
Impedance of whole body 0.5 2.5 8.4 1.2 1.9 -0.1 -2.0 0.1 -1.7 -2.9 0.4
Leg fat mass (left) 0.3 1.2 3.1 -0.0 -1.1 1.1 1.2 -1.2 0.8 0.6 -1.7
Arm predicted mass (left) 0.3 1.5 3.0 -1.4 -1.7 -0.4 0.7 -1.5 1.3 1.3 -0.4