Hub : Genes

ANKDD1A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1780 0.0490 7.2e-09 0.107 0.086 0.114 0.103 0.112 6.2e-13 1.2e-10 9.4e-14 1.8e-12 1.8e-13
2 GTEx Adipose Subcutaneous 0.2410 0.0670 3.4e-06 0.052 NA 0.010 NA 0.035 4.1e-05 NA 4.4e-02 NA 6.7e-04
3 GTEx Artery Aorta 0.2600 0.0730 4.2e-07 0.071 NA 0.132 NA 0.132 9.4e-05 NA 9.8e-08 NA 1.0e-07
4 GTEx Artery Tibial 0.3170 0.0577 6.1e-16 0.115 NA 0.255 NA 0.245 2.7e-09 NA 5.5e-20 NA 3.4e-19
5 GTEx Brain Cerebellar Hemisphere 0.3590 0.0930 1.5e-04 0.218 NA 0.228 NA 0.205 2.6e-06 NA 1.5e-06 NA 5.6e-06
6 GTEx Cells EBV-transformed lymphocytes 0.4430 0.0730 3.1e-11 0.559 NA 0.489 NA 0.554 1.2e-21 NA 4.3e-18 NA 2.2e-21
7 GTEx Cells Transformed fibroblasts 0.1330 0.0490 3.1e-03 0.062 NA 0.057 NA 0.048 2.0e-05 NA 4.2e-05 NA 1.7e-04
8 GTEx Colon Sigmoid 0.2760 0.0860 6.7e-06 0.170 NA 0.122 NA 0.136 1.3e-06 NA 4.5e-05 NA 1.6e-05
9 GTEx Esophagus Gastroesophageal Junction 0.2870 0.1010 9.1e-04 0.000 NA 0.060 NA 0.032 3.2e-01 NA 3.2e-03 NA 2.5e-02
10 GTEx Esophagus Mucosa 0.1450 0.0400 2.4e-08 0.158 NA 0.149 NA 0.170 1.0e-10 NA 3.8e-10 NA 1.8e-11
11 GTEx Esophagus Muscularis 0.1690 0.0510 5.5e-06 0.106 NA 0.101 NA 0.125 5.7e-07 NA 1.1e-06 NA 4.9e-08
12 GTEx Heart Atrial Appendage 0.1440 0.0610 3.7e-03 0.112 NA 0.041 NA 0.057 1.0e-05 NA 6.2e-03 NA 1.4e-03
13 GTEx Nerve Tibial 0.1255 0.0515 4.0e-03 0.048 NA 0.011 NA 0.023 2.6e-04 NA 5.2e-02 NA 8.4e-03
14 GTEx Pancreas 0.1880 0.0670 8.4e-04 0.049 NA 0.037 NA 0.020 3.8e-03 NA 1.1e-02 NA 4.9e-02
15 GTEx Spleen 0.3090 0.1380 6.1e-03 0.056 NA 0.156 NA 0.082 1.5e-02 NA 8.4e-05 NA 4.0e-03
16 GTEx Whole Blood 0.1360 0.0450 6.5e-06 0.069 NA 0.058 NA 0.055 6.0e-07 NA 4.6e-06 NA 7.5e-06
17 METSIM Adipose 0.0529 0.0192 2.2e-06 0.018 0.043 0.029 0.041 0.027 9.6e-04 4.0e-07 3.4e-05 7.7e-07 4.8e-05
18 NTR Blood 0.1385 0.0285 0.0e+00 0.087 0.085 0.091 0.094 0.093 1.6e-26 4.6e-26 6.5e-28 1.0e-28 1.9e-28
19 TCGA Breast Invasive Carcinoma 0.0747 0.0290 1.9e-11 0.061 0.060 0.060 NA 0.063 1.6e-12 2.6e-12 2.7e-12 NA 8.6e-13
20 TCGA Cervical Squamous Cell Carcinoma 0.1140 0.0530 6.9e-04 0.132 0.065 0.125 NA 0.126 4.9e-07 4.2e-04 9.8e-07 NA 9.0e-07
21 TCGA Colon Adenocarcinoma 0.1340 0.0570 1.5e-04 0.098 0.080 0.058 NA 0.066 2.7e-06 2.2e-05 2.9e-04 NA 1.1e-04
22 TCGA Esophageal Carcinoma 0.1870 0.0910 1.1e-03 0.060 0.129 0.120 NA 0.090 5.8e-03 6.8e-05 1.2e-04 NA 8.5e-04
23 TCGA Head and Neck Squamous Cell Carcinoma 0.0892 0.0320 1.3e-09 0.100 0.087 0.091 NA 0.091 2.7e-11 5.9e-10 2.3e-10 NA 2.2e-10
24 TCGA Kidney Renal Clear Cell Carcinoma 0.0674 0.0265 1.6e-06 0.029 0.064 0.052 NA 0.045 2.7e-04 9.8e-08 1.6e-06 NA 8.4e-06
25 TCGA Lung Adenocarcinoma 0.0502 0.0227 8.0e-06 0.029 0.052 0.060 NA 0.049 2.3e-04 1.0e-06 1.5e-07 NA 2.1e-06
26 TCGA Lung Squamous Cell Carcinoma 0.1259 0.0423 1.2e-11 0.123 0.122 0.118 NA 0.116 8.8e-14 1.1e-13 2.9e-13 NA 4.5e-13
27 TCGA Ovarian Serous Cystadenocarcinoma 0.1110 0.0510 2.0e-03 0.014 0.032 0.016 NA 0.018 3.8e-02 2.9e-03 2.6e-02 NA 2.2e-02
28 TCGA Pancreatic Adenocarcinoma 0.0680 0.0410 8.0e-03 0.025 0.039 0.027 NA 0.015 3.1e-02 9.6e-03 2.6e-02 NA 7.7e-02
29 TCGA Pheochromocytoma and Paraganglioma 0.0960 0.0490 2.9e-03 0.113 0.042 0.072 NA 0.095 3.1e-05 8.6e-03 8.5e-04 NA 1.3e-04
30 TCGA Prostate Adenocarcinoma 0.0868 0.0486 8.9e-04 -0.001 0.016 0.022 NA -0.001 3.9e-01 7.9e-03 1.9e-03 NA 3.8e-01
31 TCGA Stomach Adenocarcinoma 0.1330 0.0480 2.8e-07 0.117 0.105 0.109 NA 0.113 8.0e-09 5.4e-08 2.9e-08 NA 1.5e-08
32 TCGA Testicular Germ Cell Tumors 0.1370 0.0740 7.9e-03 0.088 0.062 0.064 NA 0.061 5.0e-04 3.2e-03 2.7e-03 NA 3.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
Bipolar Disorder (2018) 0.6 1.0 4.2 -0.4 -0.5 -0.3 0.3 -1.1 1.2 -1.2 0.1 0.1 0.8 0.5 0.4 -0.6 -1.0 2.1 -1.0 0.3 0.7 1.4 1.7 1.4 1.1 1.1 0.6 0.7 1.4 1.0 0.8 0.1 0.4 1.4 1.3
Bipolar Disorder or Schizophrenia 0.1 0.3 2.4 0.5 -0.3 -0.0 0.2 0.1 -0.1 -0.3 -0.3 -0.7 -0.1 -0.1 1.4 -0.1 -0.2 0.0 -1.6 -0.2 -0.4 0.0 0.4 0.1 0.3 -0.0 -0.2 -0.3 0.5 -0.2 -0.2 1.2 -1.5 0.1 1.0
Depressed Affect (Nagel 2018) 0.9 1.9 7.6 -2.6 -0.0 1.0 0.2 -0.8 1.2 -1.1 1.6 1.0 1.6 0.5 -0.7 1.0 1.4 0.0 0.9 1.2 1.2 1.5 1.4 1.8 1.5 1.3 0.6 1.6 2.4 2.8 1.3 -1.4 -0.4 1.4 1.9
Depression (Nagel 2018) 2.0 3.0 12.1 -3.5 0.7 2.1 2.0 -2.6 1.3 -0.0 2.8 0.8 1.9 2.2 -0.1 1.4 1.0 0.6 1.3 1.9 0.7 1.5 1.6 1.5 2.0 1.8 1.4 2.0 1.5 1.4 2.2 -2.6 -0.4 1.7 1.2
Intelligence (Savage-Jansen 2018) 0.2 0.7 4.8 -1.7 -1.5 0.9 -0.2 -2.2 0.2 0.2 1.4 -0.0 0.4 0.6 -0.7 0.4 -0.1 1.0 1.0 1.1 -0.2 0.4 0.4 0.3 0.6 0.5 -0.6 0.6 0.6 1.1 0.6 -1.2 0.1 0.3 0.4
Neuroticism (Nagel 2018) 1.0 2.3 6.4 -2.5 1.4 2.1 1.0 -0.9 1.0 -0.3 2.2 0.7 1.8 1.0 0.4 1.9 2.5 0.1 1.1 1.3 0.7 1.2 1.1 1.3 2.0 1.2 0.6 1.9 2.2 2.3 1.6 -1.2 -0.4 1.3 2.2
Schizophrenia (2018) 0.5 1.0 5.0 0.9 -0.0 0.2 0.0 1.1 -1.1 0.7 -0.4 -0.9 -0.8 -0.6 1.6 0.4 0.6 -1.7 -1.4 -0.5 -1.0 -1.1 -0.9 -1.0 -0.5 -1.0 -0.8 -0.8 -0.6 -1.1 -0.8 1.5 -2.2 -0.9 0.3
Schizophrenia vs Biploar Disorder 0.3 0.4 2.4 -0.4 0.9 1.0 0.6 -0.6 0.4 -0.1 1.0 0.7 0.4 0.6 0.4 0.7 0.3 -1.6 1.4 0.4 0.0 0.1 0.3 0.1 0.4 0.4 0.7 0.4 -0.1 -0.3 0.5 -0.5 -0.9 0.3 0.5
Worry (Nagel 2018) 0.3 0.6 2.7 -0.8 1.4 1.6 0.9 -0.0 -0.7 1.5 0.9 -0.5 0.1 0.6 0.7 1.4 1.6 -0.5 0.2 -0.5 -0.8 -0.2 -0.5 -0.2 0.5 -0.5 -0.2 -0.0 0.3 0.1 0.3 -0.1 -1.1 -0.4 0.8
Alzheimer’s Disease (in mother) 0.2 0.2 1.5 -1.2 -0.4 0.1 -0.4 -0.0 -0.1 0.6 0.4 0.5 0.1 -0.0 0.2 -0.3 -0.5 -1.2 1.2 0.3 0.5 0.2 0.3 0.5 -0.3 0.2 0.0 -0.2 0.3 0.3 -0.2 -0.4 -0.1 0.2 0.3
Alzheimer’s Disease (in father) 2.4 2.6 4.7 -1.1 2.1 1.9 2.2 -1.0 1.4 0.8 2.0 1.3 2.0 1.6 1.9 1.8 1.8 0.4 1.9 1.4 2.0 1.8 1.4 1.8 1.5 1.6 1.9 1.8 1.7 1.8 1.9 -1.7 0.3 1.5 0.7
Alzheimer’s Disease (including proxy) 0.5 0.7 3.0 -1.3 0.4 0.8 0.8 -0.3 0.4 1.4 1.2 0.8 0.7 0.9 -0.3 0.4 0.7 -0.8 1.7 0.3 1.0 0.8 0.7 1.0 0.2 0.6 0.8 0.4 0.8 0.7 0.6 -1.2 0.3 0.6 0.2
Crohns Disease (2017) 0.6 1.3 8.0 0.5 0.2 -0.1 -0.6 1.7 0.4 -2.8 -0.7 0.0 0.2 -1.8 2.4 1.7 1.0 0.0 -1.1 2.4 0.8 0.5 0.5 0.3 0.0 0.1 0.8 0.3 0.6 1.1 -0.1 1.6 -1.5 0.4 0.1
Irritable Bowel Disease (IBD) 0.3 0.7 3.5 0.5 0.8 0.9 0.2 0.9 -0.5 -0.8 -0.1 0.9 -0.2 -0.7 1.9 1.9 1.0 -0.6 -0.9 1.7 -0.1 -0.1 -0.3 -0.2 -0.4 -0.5 0.7 -0.2 -0.4 -0.1 -0.1 0.6 -1.3 -0.3 -0.8
Ulcerative Colitis (UC) 0.3 0.7 2.0 0.3 0.9 0.9 0.6 0.0 -1.2 1.2 0.3 1.0 -0.7 0.5 0.7 1.0 0.5 -0.7 -0.5 0.1 -1.0 -0.8 -1.0 -0.7 -0.7 -0.9 0.2 -0.8 -1.2 -1.1 -0.2 -0.3 -0.9 -1.0 -1.4
Major Depression (MDD) 3.6 4.3 7.8 -2.3 2.3 1.3 2.5 -1.8 2.7 -1.4 2.4 0.0 2.4 1.4 1.6 1.3 1.7 1.7 1.3 2.7 2.6 2.5 2.5 2.8 1.7 2.6 2.4 2.2 2.3 2.1 2.1 -1.2 1.3 2.5 2.4
Reaction Time 0.1 0.3 2.3 -0.3 1.0 -0.0 0.3 -0.7 0.5 -0.2 0.2 1.5 0.6 0.4 0.2 -0.4 -0.2 0.8 0.2 -0.0 0.6 0.5 0.4 0.5 0.3 0.6 0.4 0.3 0.4 0.3 0.4 -0.6 0.4 0.5 -0.0
Verbal and Numeric Reasoning (VNR) 0.9 2.0 5.3 -2.0 -2.3 0.1 -0.8 -2.2 1.6 -1.0 1.6 -0.4 1.4 0.7 -1.6 -0.3 -0.5 1.4 2.2 1.6 1.0 1.5 1.6 1.3 1.3 1.7 -0.1 1.2 1.8 2.0 1.0 -1.5 0.7 1.6 1.5
Breast Cancer 0.4 0.9 7.0 -0.9 0.2 0.7 0.5 -1.0 1.1 -0.3 1.2 -0.9 1.0 1.1 0.7 -0.2 0.2 0.2 2.6 0.7 0.2 0.6 1.1 0.7 1.3 1.2 0.7 0.9 0.6 0.1 1.1 -1.0 -1.1 1.1 1.0
Ovarian Cancer 1.5 2.0 12.4 0.9 -0.6 0.3 -0.3 -0.1 -2.0 3.5 -0.4 -1.1 -1.8 -0.5 0.5 -0.2 -0.4 -1.7 -1.4 -0.7 -1.6 -1.6 -2.1 -1.8 -1.4 -1.8 -1.5 -1.2 -2.1 -1.2 -1.2 -0.4 1.1 -2.0 -1.3
Prostate Cancer 0.9 1.2 4.5 -0.2 -0.3 0.2 0.8 -1.5 1.4 -1.7 0.6 -0.4 1.2 1.0 -0.8 0.5 0.2 2.1 -0.7 0.5 0.7 1.4 1.6 1.2 1.5 1.3 1.6 1.1 0.8 0.7 1.5 -1.1 0.9 1.5 0.4
Age at First Birth 0.4 0.6 4.3 -0.6 0.1 0.6 -0.1 -0.9 0.8 -2.1 0.8 0.8 0.3 0.4 0.2 0.5 -0.8 0.6 1.0 0.9 -0.2 0.3 0.7 0.2 0.6 0.8 1.0 0.9 -0.2 -0.2 0.9 -0.6 -1.2 0.7 -0.2
Bipolar Disorder (2011) 1.0 1.0 9.9 -1.1 -0.3 -0.5 0.6 -1.6 1.3 -0.8 0.2 1.4 1.1 1.4 -0.2 -1.6 -2.3 3.1 0.6 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.1 1.6 6.0 1.7 -1.2 -2.1 -1.3 1.5 -0.5 -1.0 -1.8 -2.5 -0.9 -1.4 -0.7 -1.6 -1.0 -0.4 -2.4 -1.6 -0.4 -0.8 -0.6 -0.9 -0.9 -1.0 -1.0 -1.0 -0.6 -0.5 -1.2 1.6 -0.0 -0.7 -0.7
Coronary Artery Disease (CAD) 0.4 0.5 2.1 0.3 -1.5 -0.7 -0.4 -0.3 -0.3 -0.2 -0.3 -0.8 -0.5 -0.1 -0.2 -1.3 -1.4 0.6 -1.2 1.0 -0.3 -0.8 -0.4 -0.4 -0.7 -0.3 -0.4 -0.7 -0.7 -0.6 -0.5 0.0 -0.0 -0.4 -1.0
Crohns Disease (2012) 0.7 1.1 3.9 0.7 -1.1 -1.5 -1.3 1.5 0.8 -2.0 -0.9 -1.2 0.4 -1.7 0.9 -0.3 -0.4 0.6 -0.9 1.6 1.6 0.8 0.9 0.7 -0.0 0.4 0.3 0.4 1.0 1.5 -0.3 1.1 0.5 0.7 0.6
Mean Putamen Volume 0.6 0.7 4.4 -0.1 -0.8 -0.8 -0.2 0.2 -0.7 1.2 -0.4 -1.5 -0.7 -0.8 1.3 -0.6 0.6 -2.1 -0.3 -0.2 -0.3 -0.4 -0.8 -0.1 -0.9 -0.7 -1.4 -1.0 0.1 0.8 -1.0 0.3 -0.3 -0.8 -0.4
Fasting Glucose 2.7 3.3 8.0 -2.4 2.4 2.5 2.8 -2.3 1.5 0.6 2.5 1.4 1.5 2.1 1.3 2.4 1.2 1.3 2.1 2.2 1.1 1.5 1.4 1.6 1.3 1.7 2.2 1.6 0.7 1.1 2.1 -2.6 0.2 1.5 0.6
HbA1C 1.2 1.3 3.5 -0.4 0.7 -0.1 -0.2 -1.0 1.5 -0.5 0.6 0.9 1.3 0.3 -0.6 0.4 -1.2 1.0 1.3 1.2 1.9 1.4 1.4 1.6 0.9 1.5 1.6 1.2 1.4 1.2 1.0 -0.7 1.2 1.5 1.5
HDL Cholesterol 0.6 0.9 2.8 0.9 0.1 -0.3 -0.6 1.1 -1.4 1.1 -0.6 -0.3 -1.2 -0.4 0.1 -0.3 -0.1 -0.5 -0.0 -1.1 -1.4 -1.3 -1.3 -1.7 -0.7 -1.3 -1.4 -0.7 -1.2 -1.1 -1.0 0.9 -0.5 -1.3 -0.8
LDL Cholesterol 1.1 1.7 6.2 -0.3 -1.6 -1.1 -0.8 -0.4 1.7 -2.5 -0.3 0.3 1.4 -0.4 0.7 -1.3 -1.2 1.2 1.0 1.6 2.1 1.7 1.9 1.5 1.0 1.6 0.8 1.0 1.8 1.6 0.7 -0.0 1.2 1.8 1.3
Lupus 2.6 3.9 11.5 0.6 0.2 0.1 0.3 0.7 -2.6 3.3 -0.3 -0.1 -2.5 -0.4 0.9 0.6 1.1 -2.5 -1.9 -1.6 -2.8 -2.6 -2.7 -3.1 -2.0 -2.4 -2.0 -1.2 -3.4 -2.1 -1.4 -0.3 -0.8 -2.7 -3.3
Neuroticism (2016) 0.8 1.2 4.4 -2.1 0.0 0.7 0.6 -1.0 0.7 -0.6 1.3 -1.0 1.0 0.4 1.1 1.0 1.9 0.1 0.6 1.3 0.6 0.7 0.7 0.8 1.3 0.9 -0.0 1.5 1.4 1.6 1.0 -1.3 -1.1 0.8 1.7
Primary Biliary Cirrhosis 0.6 0.9 3.3 -0.0 -1.8 0.1 0.7 -0.9 -0.8 1.7 0.4 -0.5 -0.6 1.4 -1.2 -1.7 -1.5 0.3 -0.6 -0.8 -0.8 -0.9 -0.9 -0.7 -0.6 -0.5 -0.7 -0.9 -0.8 -1.6 -0.4 -0.3 -0.1 -0.8 -0.7
Rheumatoid Arthritis 1.1 1.5 3.2 1.6 -1.0 -0.8 -0.8 0.5 -1.3 1.4 -0.7 -0.8 -1.0 -0.4 -0.6 -1.7 -1.0 -0.6 -1.5 -1.8 -1.2 -1.5 -1.4 -1.5 -1.6 -1.2 -1.2 -1.5 -1.5 -1.8 -1.4 0.6 0.6 -1.3 -1.1
Schizophrenia (2014) 0.3 0.6 2.6 -0.0 -1.4 -0.9 -0.2 0.1 -0.5 0.6 -0.2 -1.2 -0.7 -0.1 1.6 -0.9 -1.1 -1.1 -1.2 -0.7 -0.4 -0.4 -0.2 -0.2 -0.4 -0.4 -1.0 -0.8 0.1 -0.3 -0.7 1.1 -1.4 -0.4 0.4
Triglycerides 1.2 2.0 7.0 -1.2 0.3 0.6 0.2 -1.2 1.3 -0.2 1.1 0.0 1.7 1.1 -2.5 0.2 -1.3 0.5 2.7 1.9 1.9 1.4 1.5 1.7 0.8 1.5 2.1 1.0 0.9 0.7 1.4 -1.7 2.4 1.5 0.4
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.5 -0.7 -0.5 -0.4 0.2 -0.5 0.5 -0.9 0.3 0.9 0.1 -0.0 0.9 -0.7 -0.6 0.4 0.3 1.2 0.4 0.2 0.6 0.5 -0.1 0.7 0.1 0.1 0.1 0.2 0.0 -0.5 -0.3 0.5 -0.1
Ulcerative Colitis 0.1 0.2 0.9 0.3 0.5 0.7 0.7 0.1 -0.7 0.8 0.2 0.3 0.0 0.4 -0.4 0.6 0.5 0.9 -0.6 0.7 -0.0 -0.2 -0.4 0.0 -0.1 -0.5 0.6 -0.1 -0.3 -0.3 0.1 -0.2 -0.1 -0.4 -0.3
Blood Eosinophil Count 0.9 6.7 16.1 0.5 1.1 1.9 2.6 -0.4 -3.9 3.7 0.4 0.6 -2.8 0.9 1.2 0.8 1.8 -2.7 -2.0 -2.3 -4.0 -3.6 -3.9 -3.0 -2.2 -3.1 -1.8 -2.6 -3.6 -3.3 -1.4 -0.1 -3.6 -3.6 -3.7
Blood Platelet Count 3.1 35.8 337.0 -1.2 5.2 7.7 8.0 -4.5 -7.3 18.4 4.4 6.3 -3.6 7.4 -1.2 0.3 -0.3 -0.7 -0.3 -5.8 -7.0 -6.0 -7.1 -5.1 -3.1 -4.3 -2.9 -3.7 -6.9 -8.8 -1.2 -4.7 -3.0 -6.2 -3.9
Blood Red Count 0.4 3.5 30.8 -2.0 -3.0 -1.3 -3.4 -0.5 -0.3 0.5 0.2 -0.8 -1.1 0.7 -1.8 -1.7 -5.5 3.1 4.3 -2.0 -0.9 -0.3 -0.6 0.1 -1.1 -0.2 -1.7 -1.2 -0.3 0.2 -0.6 -1.4 0.5 -0.7 -1.1
Blood White Count 0.4 3.3 12.1 2.4 -2.0 -0.4 -1.7 1.8 -2.0 -0.5 -2.2 1.1 -1.7 -1.3 -0.7 -1.7 -3.5 0.6 -1.4 2.6 -0.1 -2.0 -1.8 -2.0 -1.8 -2.0 -1.1 -1.9 -1.7 -2.6 -2.1 2.8 -1.1 -1.8 -1.2
Heel T-Score 0.2 1.5 8.3 0.2 -1.5 -1.6 0.6 -0.4 0.4 -0.7 -0.6 2.6 0.0 -1.3 0.6 -2.5 1.4 -1.2 -2.9 1.0 0.4 0.2 0.7 0.3 -0.5 0.2 -1.4 -0.4 0.5 1.4 -0.8 0.3 2.5 0.4 -0.7
BMI 0.2 1.4 9.5 -0.5 -2.2 -2.5 -0.1 0.1 -0.6 -0.9 -1.0 -1.0 -1.0 0.2 -0.5 -3.1 -1.8 1.6 -1.8 -2.0 -0.4 -0.7 -0.5 -0.2 -0.3 -0.5 -1.6 -1.1 0.0 -0.3 -0.8 -0.5 -0.7 -0.6 0.3
Height 0.6 12.5 71.2 -3.6 4.6 4.7 1.5 -3.7 3.2 1.3 4.9 2.3 3.6 3.8 -2.2 4.6 1.4 1.9 8.4 1.4 2.4 3.2 3.0 3.5 2.9 3.7 4.7 3.5 2.4 1.8 4.0 -3.9 -0.3 3.3 3.1
Waist Hip Ratio (WHR) 0.2 1.0 5.0 0.7 1.2 0.5 -0.3 0.4 -0.2 -1.2 -0.1 -0.7 -0.6 -1.2 2.2 1.6 2.2 -1.3 1.3 1.2 -1.0 -0.7 -0.3 -0.7 -0.4 -0.4 0.4 -0.4 -1.0 -0.6 -0.4 1.0 -1.5 -0.3 -0.5
Systolic Blood Pressure 0.4 1.8 9.4 0.6 2.2 0.2 1.0 1.0 -1.5 0.7 -1.1 -0.6 -1.1 -0.4 2.0 1.1 1.0 -1.5 -3.1 -2.0 -1.6 -1.4 -1.7 -1.1 -0.8 -1.5 -0.5 -1.2 -1.4 -0.9 -0.6 -0.1 -1.3 -1.5 -1.6
Smoking Status 0.5 1.3 8.5 -0.9 0.3 1.3 0.7 -1.0 1.3 -0.0 1.0 0.7 1.4 1.0 1.2 0.5 0.1 0.3 2.9 1.0 1.1 1.0 1.1 1.3 1.1 1.4 1.7 1.1 1.0 0.4 1.2 -0.9 1.0 1.3 1.3
Allergy or Eczema 1.1 2.9 11.3 -1.6 2.7 3.4 3.2 -2.4 -0.7 2.5 2.5 1.3 0.3 3.0 1.3 2.4 1.7 1.8 0.8 0.5 -1.2 -0.5 -0.5 -0.4 0.7 0.0 1.5 0.7 -1.2 -1.7 1.6 -1.8 -0.7 -0.3 -0.7
Cardiovascular Disease 0.3 0.9 7.7 -0.4 1.7 0.8 1.7 0.2 -0.3 0.0 0.2 0.1 0.1 0.4 2.8 1.6 1.5 0.2 -2.1 -0.4 -0.8 0.0 -0.5 -0.1 0.9 -0.2 0.1 0.3 0.3 0.6 0.6 -0.5 -1.5 -0.3 0.3
Hypothyroidism (self reported) 2.5 5.7 9.9 -2.1 1.7 2.4 2.7 -2.9 2.8 -2.1 2.6 2.5 2.6 2.5 2.1 2.2 1.4 2.7 0.2 2.6 1.4 2.4 2.6 2.4 3.1 2.8 2.7 2.5 2.3 1.7 3.0 -2.2 0.1 2.7 2.8
Respiratory disease 0.7 1.6 12.1 0.0 1.5 2.5 2.2 -1.0 -1.2 3.5 0.7 0.7 -0.2 1.7 2.6 1.2 0.0 0.1 0.2 -0.6 -0.3 -0.5 -1.3 -0.0 -0.7 -0.6 0.5 -0.8 -0.8 -0.9 0.1 -1.2 1.1 -0.9 -1.4
Type 2 Diabetes (T2D) (2018) 1.3 2.5 6.2 1.8 -1.6 -2.2 -2.0 1.4 -1.5 0.5 -1.7 -1.1 -2.1 -1.4 -0.6 -2.2 -2.5 -0.6 -1.0 -1.7 -1.2 -1.5 -1.3 -1.2 -1.7 -1.6 -1.8 -2.1 -1.1 -1.4 -2.2 1.7 -0.9 -1.6 0.0
Lung FEV1/FVC ratio 3.6 18.2 35.0 -5.2 -1.4 1.8 3.7 -4.3 5.8 -2.2 5.1 2.3 5.4 4.5 -0.3 -0.5 1.6 0.7 4.4 5.0 4.2 4.8 5.4 4.4 5.5 5.9 2.5 5.8 4.7 4.5 5.2 -4.9 3.7 5.4 4.4
Lung FVC 0.6 3.2 10.3 -2.9 0.3 2.0 1.7 -3.0 1.2 0.9 3.1 3.2 1.6 2.2 -2.5 0.4 1.0 2.0 1.7 1.3 0.4 1.0 1.4 1.2 1.8 1.6 0.7 2.0 1.1 1.1 2.0 -2.9 -0.2 1.4 1.6
Neuroticism 1.1 2.6 7.6 -2.7 1.1 2.1 1.2 -1.0 1.4 -0.2 2.0 1.1 1.8 1.0 0.3 1.6 1.9 0.7 1.3 1.7 1.2 1.6 1.3 1.7 2.0 1.5 0.6 2.0 2.4 2.7 1.7 -1.4 -0.3 1.4 2.2
Chronotype (morning person) 1.2 2.7 8.1 -1.6 -1.4 -0.4 0.7 -1.1 2.4 -0.5 1.0 0.8 2.0 1.5 0.1 -1.6 -1.1 0.9 1.3 0.7 2.8 2.3 2.0 2.3 1.5 2.4 1.1 1.7 2.5 1.6 1.3 -1.4 1.1 2.1 2.4
Hair Pigment 0.0 0.5 3.1 0.5 1.4 0.8 0.9 -0.1 -0.0 0.8 0.6 -0.4 0.4 0.4 0.9 1.3 1.8 -0.2 -0.4 0.6 0.7 0.3 -0.2 0.2 0.6 0.0 0.8 0.9 0.1 0.5 0.6 -0.4 0.8 -0.0 0.6
Tanning 0.2 2.4 8.3 1.1 0.9 0.1 -0.1 1.0 -1.9 0.9 -1.1 0.8 -2.0 -1.2 0.7 0.1 -0.1 -1.3 -1.0 -1.9 -2.9 -2.2 -1.8 -2.0 -1.6 -1.7 -1.3 -1.8 -2.2 -2.4 -1.6 1.4 -2.1 -1.8 -1.0
Hand grip strength (left) 0.6 1.5 5.2 -1.5 0.8 -0.5 -0.7 -0.3 1.6 -2.1 0.7 -0.2 1.3 -0.6 0.8 1.3 1.5 0.0 1.9 0.5 1.5 1.4 1.5 1.7 0.7 1.4 0.9 1.1 1.7 2.3 0.8 -0.5 -0.1 1.5 0.8
Number of treatments/medications taken 1.7 3.1 7.0 1.6 -0.5 -0.2 0.3 1.1 -2.4 2.2 -1.4 -2.2 -1.8 -0.2 2.3 -0.5 -0.0 -1.5 -2.0 -2.1 -2.7 -2.0 -2.5 -2.2 -1.2 -2.3 -1.9 -2.1 -1.7 -2.0 -1.4 1.1 -1.2 -2.3 -1.8
Average weekly spirits intake 0.3 0.3 3.9 -0.1 -0.2 0.5 0.8 0.1 -0.3 0.7 0.3 -0.5 0.2 0.7 -0.2 -0.1 1.0 -2.0 0.0 -0.3 -0.5 -0.2 -0.3 -0.5 0.7 -0.2 -0.4 0.5 0.2 -0.2 0.2 -0.1 -0.9 -0.2 0.8
Sensitivity / hurt feelings 0.9 1.6 7.5 -2.4 1.3 0.4 0.7 -0.4 1.5 -1.1 1.4 0.7 1.4 -0.2 0.8 1.4 2.7 -0.5 -0.4 0.9 1.1 1.3 1.2 1.1 0.9 1.3 0.4 1.6 1.5 2.3 1.0 -1.4 0.1 1.3 1.2
Frequency of depressed mood in last 2 weeks 2.0 2.9 6.8 -2.6 0.5 1.9 1.4 -1.6 1.5 -0.4 2.4 0.4 2.1 1.4 0.6 1.3 1.3 0.3 1.0 2.2 1.4 1.8 1.9 1.8 2.2 1.9 1.3 2.3 2.3 2.1 2.0 -1.7 -0.3 1.9 2.1
Hearing difficulty/problems: Yes 0.6 0.9 5.4 -0.6 1.6 2.3 1.5 -1.0 -0.4 1.4 1.1 0.5 0.5 0.6 1.4 1.7 1.5 -0.4 -1.3 1.0 -0.5 -0.3 -0.5 -0.2 0.2 -0.1 0.6 0.5 -0.4 -0.2 0.6 -0.9 -0.5 -0.2 -0.2
Relative age of first facial hair 0.9 1.8 9.1 -0.8 0.3 0.2 -0.1 0.4 1.4 -2.1 0.0 0.5 1.4 -0.5 2.2 1.2 0.7 1.4 1.1 3.0 2.2 1.6 1.3 1.4 0.9 1.2 1.3 1.2 1.4 2.0 1.0 -0.1 1.8 1.4 0.4
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 3.6 -0.7 -0.1 1.1 0.8 -0.2 0.3 -0.7 0.6 0.4 1.2 0.6 -0.0 0.1 0.7 -0.0 0.2 1.9 -0.7 0.2 0.5 -0.2 1.1 0.6 0.1 0.8 0.6 0.2 0.8 0.1 -1.8 0.7 0.2
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.9 -0.6 0.1 0.6 0.8 -0.7 0.8 -0.1 0.9 -1.7 0.8 1.2 0.8 0.3 0.3 0.1 1.4 0.8 0.8 0.5 0.7 0.7 0.6 0.9 1.5 0.5 0.2 -0.4 0.9 -0.5 -1.5 0.8 -0.0
Ever had hysterectomy (womb removed) 0.3 0.3 2.3 0.4 0.1 1.0 0.8 -0.6 -0.1 0.5 0.6 0.2 0.1 1.0 0.2 0.5 -0.4 0.2 1.2 0.8 0.1 -0.0 0.0 -0.3 -0.1 0.2 1.0 -0.1 -0.8 -1.5 0.4 -0.1 -0.3 0.1 -0.6
Systolic blood pressure, automated reading 0.3 0.8 7.1 -0.0 1.1 -0.8 0.6 0.2 0.2 -0.7 -0.7 -2.7 -0.2 0.3 1.4 0.2 0.5 -0.4 -1.6 -2.5 -0.3 -0.1 -0.2 0.1 0.3 -0.0 0.5 -0.3 -0.3 -0.1 0.3 -0.7 -1.4 -0.1 -0.2
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 1.6 -0.5 0.2 -0.7 -1.1 -0.5 -0.1 0.1 0.3 0.4 -0.5 -0.6 0.2 -0.0 -0.2 0.3 0.7 -0.4 -0.3 -0.3 -0.2 0.0 -0.6 -0.2 -0.5 -0.6 -0.2 0.2 -0.5 -0.7 -1.3 -0.3 0.4
Angina 1.0 1.3 5.3 0.1 1.3 0.8 -0.1 0.4 1.1 -1.0 0.4 1.5 1.4 -0.5 1.6 1.1 1.6 0.1 0.9 2.3 1.5 1.1 0.8 0.9 1.1 0.9 0.7 1.3 1.4 1.5 0.6 0.2 1.3 1.0 2.1
Medication for hormone replacement therapy 0.6 0.7 4.0 0.8 -0.2 -0.3 -0.6 0.6 -0.5 -0.2 -0.3 -0.2 -0.8 -1.0 2.0 0.1 0.7 -1.8 -0.0 0.4 -0.3 -0.5 -0.2 -0.7 -1.3 -0.5 -0.5 -0.9 -1.1 -0.7 -0.9 1.0 0.0 -0.5 -1.4
Vitamin and mineral supplements 0.5 0.7 2.5 0.2 -0.2 -0.1 0.7 0.0 0.9 -1.5 -0.2 0.8 0.4 0.3 0.0 0.7 0.9 1.6 -0.4 1.3 1.0 1.0 0.9 0.7 1.1 0.6 1.2 0.6 0.6 0.3 0.8 0.4 1.5 0.8 0.9
Supplements: Zinc 2.1 2.3 6.8 -2.6 -0.1 1.0 1.5 -1.2 1.4 -0.3 2.3 0.8 1.6 1.9 0.7 0.2 0.0 1.0 2.6 1.5 1.0 1.7 1.5 1.8 1.6 1.7 0.5 1.3 2.1 1.8 1.6 -1.9 0.4 1.5 1.5
Medication: Co-codamol 5.6 6.5 14.0 -2.4 -0.4 0.7 1.5 -2.3 3.3 -1.5 2.0 1.9 3.2 2.5 0.9 -0.3 0.2 2.5 3.2 1.9 2.6 3.6 3.4 3.3 3.5 3.3 2.0 2.6 3.7 2.8 2.9 -2.4 1.1 3.3 3.7
Medication: Metformin 0.3 0.4 1.6 0.7 -0.4 -0.5 -0.2 0.0 -0.5 1.2 -0.4 -0.5 -0.7 0.4 -0.9 -1.3 -0.9 0.2 -0.2 -1.3 -0.8 -0.5 -0.5 -0.4 -0.2 -0.5 -0.9 -0.7 -0.2 -0.8 -0.6 0.5 0.1 -0.6 1.0
Diabetes (father) 0.7 0.8 6.8 -1.2 1.1 0.6 0.2 -0.6 0.3 -0.1 0.4 2.6 0.5 1.1 0.4 -0.5 -1.9 0.7 2.1 0.0 0.6 0.5 0.6 1.1 0.4 0.6 0.6 0.1 1.0 0.3 0.5 -0.8 -0.7 0.6 0.2
Diabetes (mother) 2.8 3.5 8.0 1.0 -2.4 -2.7 -2.8 1.8 -1.8 1.2 -2.7 -1.1 -2.2 -1.9 -1.4 -2.5 -2.8 -1.5 -1.1 -2.0 -0.2 -1.3 -1.6 -0.9 -2.5 -1.8 -2.1 -2.5 -0.8 -0.9 -2.6 2.1 0.1 -1.8 -1.2
Severe depression (siblings) 0.8 0.9 2.9 0.4 0.3 -0.3 -0.9 0.2 1.3 -1.7 -0.3 -0.3 1.2 -1.0 0.5 0.4 -0.4 0.6 0.5 1.5 1.6 0.9 1.0 1.0 0.7 1.0 1.0 0.8 1.2 1.1 0.3 0.9 -0.4 1.1 1.6
Pack years adult smoking proportion 0.4 0.6 3.3 0.3 -0.0 0.4 0.7 0.3 1.0 -1.0 0.1 -0.2 0.8 -0.3 1.8 0.9 1.3 0.1 -0.2 1.0 0.1 0.8 1.0 0.3 0.8 0.7 1.0 0.8 0.7 0.2 0.5 1.0 -1.4 1.0 1.0
Impedance of leg (right) 0.1 0.7 3.3 0.2 0.5 1.2 -0.5 0.5 0.5 0.8 0.2 -1.6 0.7 -0.5 1.0 1.4 0.6 -0.9 1.7 0.7 0.7 0.8 0.5 0.6 0.1 0.4 0.6 0.7 0.6 1.1 0.3 0.5 1.8 0.6 -0.1
Leg fat-free mass (left) 0.5 2.8 7.2 -2.2 1.1 0.7 1.3 -2.3 1.6 -0.7 2.1 1.8 1.5 1.8 -2.2 0.3 -0.0 2.2 2.6 0.5 1.3 1.5 1.7 1.9 1.6 1.9 1.5 1.4 1.4 1.1 1.7 -2.7 -0.5 1.7 2.1
Trunk fat percentage 0.5 2.1 5.3 -2.3 0.1 0.5 1.8 -1.4 1.3 -1.2 1.3 0.4 1.3 1.3 1.5 0.4 1.0 1.8 0.9 1.1 0.9 1.6 1.5 1.9 1.9 1.6 0.9 1.3 1.9 2.0 1.6 -2.1 0.8 1.5 2.0
Hand grip strength (right) 1.7 4.5 9.1 -3.0 1.1 1.0 0.7 -2.0 2.5 -1.6 2.2 1.4 2.2 1.3 1.3 1.8 1.6 1.4 3.0 1.7 2.7 2.6 2.3 3.0 2.1 2.5 1.9 2.2 2.8 3.0 2.2 -1.9 0.8 2.4 2.5
Townsend deprivation index at recruitment 0.3 0.4 4.1 -0.1 0.1 0.9 0.7 -0.1 -0.8 2.0 0.1 -0.5 -0.1 0.1 1.2 0.0 0.6 -1.2 -0.4 -0.2 -0.7 -0.3 -0.7 -0.5 -0.6 -0.4 -0.7 -0.6 -0.5 -0.4 -0.4 -0.3 0.2 -0.5 -0.7
Current tobacco smoking 0.2 0.4 2.4 -0.8 -0.1 1.1 1.1 -0.6 -0.1 1.6 0.3 -0.6 0.5 0.7 -0.0 0.2 0.4 0.6 0.8 0.3 0.1 0.5 0.3 0.4 0.6 0.3 0.3 0.5 0.3 0.5 0.6 -1.0 1.0 0.3 0.2
Average weekly fortified wine intake 2.4 2.8 6.2 1.0 -1.8 -2.3 -1.2 1.1 -1.7 1.3 -1.6 -1.3 -2.5 -1.1 -0.1 -1.3 -1.0 -1.3 -1.1 -2.0 -0.7 -1.4 -2.1 -1.4 -2.3 -2.1 -2.3 -2.3 -1.9 -0.8 -1.9 0.3 2.0 -2.2 -2.5
Maternal smoking around birth 0.4 0.6 3.2 -1.0 1.1 0.7 0.3 -0.6 0.5 -0.9 0.9 0.0 0.8 -0.1 1.4 1.1 1.8 -0.4 0.7 0.3 0.0 0.3 0.7 0.5 0.5 0.7 0.4 0.9 0.5 0.9 0.7 -0.7 0.4 0.7 0.3
Fed-up feelings 1.8 3.3 9.2 -2.7 0.6 1.7 1.0 -1.2 1.8 -0.8 2.1 0.7 2.2 0.9 0.4 1.6 1.6 0.8 0.8 2.5 2.1 2.2 2.0 2.2 2.0 1.9 1.4 2.5 2.7 3.0 2.0 -1.5 0.6 2.0 2.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 8.1 -2.8 -0.1 1.8 1.7 -1.8 0.6 0.2 2.0 0.5 1.2 1.7 -0.4 0.7 1.0 -0.2 0.3 0.8 -0.5 0.5 0.8 0.5 1.6 1.0 0.5 1.4 0.7 0.6 1.6 -1.9 -1.1 0.9 0.8
Relative age voice broke 0.7 1.1 2.6 -1.6 0.3 0.9 1.2 -1.1 1.1 -0.3 1.3 1.0 1.1 1.2 1.3 0.1 0.7 0.9 1.1 1.5 1.0 1.1 1.1 1.2 1.0 1.3 0.5 0.9 1.0 1.1 1.1 -1.3 1.1 1.1 0.8
Taking other prescription medications 0.6 1.0 5.5 0.8 -0.8 -0.9 -0.4 0.5 -1.0 0.5 -1.2 -2.3 -1.0 -0.5 1.5 -0.9 -0.3 -1.4 -1.3 -1.5 -1.5 -0.6 -0.7 -0.8 -0.5 -0.9 -1.2 -1.3 -0.7 -0.6 -0.9 0.3 0.0 -0.8 -0.4
Age when periods started (menarche) 0.4 1.1 4.3 -1.2 1.2 1.1 1.7 -0.8 1.1 -0.4 0.9 1.6 1.1 1.0 -0.4 0.3 0.4 1.1 0.9 2.1 0.9 0.6 0.8 0.9 0.8 1.1 1.4 1.0 0.3 0.0 1.1 -1.1 1.2 1.0 0.5
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 1.9 0.4 -0.5 -0.0 0.1 -0.3 0.0 0.7 -0.1 0.1 -0.1 0.5 0.4 -0.4 -0.8 -1.0 1.4 -0.2 0.8 0.3 0.1 0.3 -0.5 0.1 0.3 -0.4 -0.2 -0.5 -0.1 -0.1 1.2 0.1 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 4.3 1.2 -1.5 -0.8 -0.0 -0.2 -0.4 1.1 -0.8 -0.4 -0.4 -0.5 0.1 -2.1 -0.2 -1.1 -1.2 -0.9 -0.2 -0.3 -0.3 -0.5 -0.3 -0.4 -1.4 -0.2 0.1 0.4 -0.6 0.8 2.0 -0.3 -0.8
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.2 0.2 -0.6 -0.5 -0.2 -0.2 0.9 -1.1 -0.0 -0.8 0.6 0.2 0.3 -0.6 -0.5 0.8 0.5 -0.9 0.4 0.3 0.7 0.6 0.8 0.7 0.7 0.4 0.6 0.1 0.4 -0.4 -0.4 0.7 1.0
Qualifications: CSEs or equivalent 0.6 0.7 4.1 -0.7 2.0 1.4 1.4 -0.2 0.1 -0.0 0.7 2.0 0.2 0.3 -0.1 2.0 1.4 0.2 -0.8 0.7 0.1 0.4 0.2 0.3 0.0 0.3 1.0 0.5 -0.4 0.1 0.7 -0.7 0.0 0.2 -0.6
Serious illness, injury or assault to yourself 0.5 0.5 2.2 -0.8 0.3 0.1 0.6 -0.8 0.9 0.3 0.8 0.1 0.9 0.7 -0.1 -0.2 -0.2 0.2 0.4 0.7 0.8 1.0 1.0 1.2 0.5 1.0 0.6 0.3 1.0 0.6 0.5 -1.1 0.5 1.0 1.5
High blood pressure 0.7 1.9 12.4 0.5 2.1 0.7 1.0 0.7 -1.4 0.4 -0.4 -0.4 -0.7 -0.3 3.3 1.7 1.0 -0.7 -2.3 -1.8 -2.0 -1.3 -1.6 -1.2 -0.2 -1.2 -0.1 -0.8 -1.2 -0.9 -0.3 -0.1 -3.5 -1.3 -0.9
Hayfever, allergic rhinitis or eczema 0.7 1.6 5.5 -0.6 1.8 2.4 2.0 -1.4 -1.2 2.3 1.4 0.9 -0.6 1.8 1.3 1.8 1.2 1.4 0.0 -0.1 -1.4 -0.9 -1.1 -0.8 -0.1 -0.7 0.4 -0.2 -1.2 -1.6 0.4 -0.6 -1.1 -1.0 -0.9
Multivitamins +/- minerals 0.2 0.2 0.7 0.1 0.2 0.1 -0.7 -0.2 -0.3 0.5 0.3 -0.3 0.1 -0.4 0.2 -0.3 -0.6 -0.7 0.7 -0.6 -0.1 -0.3 -0.3 -0.2 -0.5 -0.1 -0.8 -0.1 0.0 0.6 -0.4 -0.3 -0.8 -0.2 -0.8
Stomach or abdominal pain in last month 1.1 1.3 9.7 -1.1 1.1 0.8 2.0 -0.9 0.4 0.1 1.3 2.3 0.5 1.2 3.1 1.0 0.8 0.6 0.3 1.5 0.8 1.1 0.6 1.0 0.9 0.7 0.8 0.9 1.0 0.9 1.0 -0.9 -1.0 0.6 0.9
Supplements: Glucosamine 0.6 0.8 5.5 0.6 -1.0 -1.8 -1.3 0.7 -0.3 -1.0 -0.8 -0.5 -0.8 -0.4 -0.1 -1.4 -1.1 -0.3 -0.5 -2.4 -0.6 -0.7 -0.6 -0.6 -0.7 -0.5 -1.0 -0.9 -0.5 -0.5 -0.7 0.6 -0.6 -0.6 -0.9
Diverticular disease/diverticulitis (self-reported) 1.4 1.6 5.1 -1.3 0.3 -0.2 0.5 -1.3 1.9 -0.3 1.0 -0.5 1.0 1.2 0.6 0.2 -0.5 0.5 1.1 1.1 1.6 2.2 1.8 1.9 1.2 1.7 1.2 1.1 1.8 1.4 1.2 -1.0 0.5 1.6 2.2
Medication: Atenolol 0.7 0.8 4.5 -0.7 1.3 1.6 2.1 -1.3 -0.3 1.4 0.9 0.4 0.2 1.6 1.0 0.8 0.6 1.7 -0.2 0.4 -0.5 0.2 0.0 0.2 0.0 0.2 0.8 -0.3 -0.7 -0.8 0.6 -1.0 -0.5 -0.0 -0.8
Medication: Levothyroxine sodium 2.1 3.5 8.0 -2.4 0.7 1.8 2.4 -2.6 2.3 -0.6 2.6 1.7 2.2 2.8 0.7 1.1 0.8 1.2 1.3 1.4 0.7 1.8 2.0 1.9 2.5 2.4 1.8 1.9 1.8 0.7 2.4 -2.0 -0.4 2.1 2.3
Sitting height 0.5 3.5 20.6 -0.9 2.5 2.0 0.4 -1.5 1.4 1.1 2.2 1.1 1.8 1.6 -4.2 1.9 0.2 1.3 4.5 0.7 2.2 1.4 1.3 1.9 0.9 1.6 2.7 1.6 1.0 0.8 1.7 -2.0 1.0 1.5 1.2
Chronic bronchitis/emphysema (father) 0.3 0.4 3.7 0.3 -0.7 0.2 -0.0 0.0 -0.0 0.1 -0.3 -1.9 0.5 -0.3 0.4 -0.3 0.9 -0.3 -1.0 1.2 -0.2 0.0 -0.1 -0.6 0.4 -0.0 -0.8 0.3 0.5 0.3 -0.1 0.6 -1.1 0.0 -0.1
High blood pressure (mother) 1.1 1.5 9.7 1.0 -0.3 -0.5 0.3 1.7 -1.2 0.3 -1.4 -1.9 -1.0 -1.0 0.5 -0.4 0.9 -1.0 -3.1 -0.8 -1.1 -1.4 -1.7 -1.7 -0.8 -1.5 -1.2 -1.1 -1.2 -1.1 -1.1 1.0 -0.8 -1.5 -0.7
Body mass index (BMI) 0.2 0.8 3.9 -1.6 -1.5 -1.5 0.8 -0.9 0.5 -0.9 0.1 -0.3 0.2 0.9 -0.2 -2.0 -0.6 1.5 -0.6 -0.8 0.2 0.5 0.7 0.8 0.6 0.6 -0.6 -0.1 1.0 0.7 0.3 -1.4 -0.0 0.5 1.1
Impedance of leg (left) 0.3 1.4 5.0 0.1 1.4 2.1 0.4 0.0 0.8 0.9 0.9 -1.1 1.2 0.3 1.3 2.2 1.3 -0.6 2.2 1.2 1.2 1.2 0.8 1.1 0.7 0.8 1.7 1.2 0.9 1.1 1.0 0.0 1.9 1.0 0.3
Leg predicted mass (left) 0.6 2.9 7.6 -2.3 1.2 0.8 1.3 -2.3 1.6 -0.7 2.2 2.0 1.6 1.9 -2.2 0.4 0.0 2.3 2.7 0.6 1.3 1.5 1.7 1.9 1.6 1.9 1.6 1.5 1.4 1.1 1.8 -2.8 -0.5 1.7 2.0
Trunk fat mass 0.6 2.8 6.8 -2.6 0.3 0.5 1.7 -1.9 1.7 -1.1 1.8 0.5 1.6 1.8 0.4 0.2 0.7 2.2 1.9 0.7 1.2 1.9 1.9 2.1 2.1 2.0 1.1 1.6 2.1 2.0 1.9 -2.6 0.6 1.8 2.4
Waist circumference 0.3 1.1 3.1 -1.8 0.2 -0.1 1.2 -1.4 1.0 -1.2 1.0 0.2 0.8 1.2 -0.5 -0.2 0.4 1.7 1.2 0.1 0.4 1.0 1.3 1.1 1.3 1.2 0.6 0.7 1.0 0.7 1.1 -1.7 -0.6 1.1 1.5
Number of incorrect matches in round 0.8 1.3 4.4 1.7 1.0 -1.0 -1.1 1.5 -0.4 -1.5 -0.4 -1.0 -1.3 -1.2 1.0 0.2 -0.6 -2.1 0.7 -0.9 -1.3 -1.2 -0.5 -1.6 -1.0 -0.8 -0.5 -0.7 -1.7 -1.5 -0.8 1.4 -1.8 -0.7 -1.1
Past tobacco smoking 1.5 2.7 13.0 2.0 -0.1 -1.4 -1.1 2.2 -2.2 1.3 -1.8 -1.2 -2.1 -1.8 -0.7 -0.4 -0.3 0.3 -3.6 -1.6 -1.0 -1.6 -2.0 -1.5 -1.7 -2.3 -2.0 -1.7 -1.2 -0.5 -2.0 1.7 -0.2 -2.2 -1.2
Alcohol usually taken with meals 0.4 0.7 2.3 0.3 0.4 -0.0 -0.6 -0.3 -0.9 1.1 -0.2 -0.6 -1.0 -0.1 -0.8 0.4 -0.3 0.4 -0.4 -1.0 -0.8 -0.9 -1.2 -0.7 -1.4 -0.9 0.0 -1.1 -1.5 -1.4 -0.8 0.4 0.9 -1.1 -1.3
Nervous feelings 0.3 0.6 4.2 -0.8 0.7 0.6 0.5 0.1 0.4 0.1 1.0 0.7 1.0 0.2 1.3 0.8 1.4 -0.6 0.1 0.5 0.2 0.5 0.5 0.4 0.9 0.5 0.0 0.8 1.2 0.8 0.5 -0.1 -2.0 0.6 1.3
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 5.4 -1.4 0.9 2.2 1.1 -0.2 1.0 -0.3 1.6 -0.2 1.7 0.7 0.2 1.9 2.3 -0.9 0.7 1.3 0.3 1.1 1.2 0.9 1.5 1.2 0.8 1.7 1.5 1.5 1.4 -0.5 -1.1 1.3 1.2
Hearing difficulty/problems with background noise 0.2 0.3 2.4 -0.1 0.8 1.1 0.2 0.3 -0.0 0.4 0.4 -1.0 0.1 -0.1 1.6 1.0 0.4 -0.2 0.2 0.2 -0.4 -0.2 -0.1 -0.3 -0.4 -0.1 0.4 0.2 -0.5 -0.2 0.1 0.1 -0.7 -0.0 -0.8
Hair/balding pattern: Pattern 2 3.0 3.8 7.0 -1.9 2.3 1.5 2.1 -1.8 2.2 -1.4 2.1 1.8 2.6 1.5 1.7 1.8 2.0 1.1 1.2 2.2 1.7 2.3 2.2 2.4 1.9 2.3 2.6 2.0 1.9 2.0 2.4 -2.1 0.1 2.4 1.2
Had menopause 0.2 0.2 1.6 0.3 0.4 -0.1 0.1 -0.3 0.3 0.5 0.3 -0.3 -0.0 0.6 1.1 0.3 -0.0 -0.2 1.3 -0.7 -0.0 -0.3 -0.4 -0.3 0.1 0.1 0.6 0.4 -0.6 -0.6 0.3 -0.1 -0.0 -0.2 -0.5
Had other major operations 0.6 0.8 2.3 -1.1 0.0 0.9 1.1 -1.5 0.9 1.4 1.1 -0.2 0.9 1.4 -1.0 0.4 0.5 0.2 -0.3 0.1 0.6 1.0 0.4 1.0 0.6 1.0 0.7 0.8 0.7 0.7 0.9 -1.5 1.3 0.7 0.7
Forced vital capacity (FVC) 0.9 3.6 12.8 -2.1 1.2 1.8 1.1 -2.8 1.3 1.7 2.8 3.4 1.3 2.2 -3.6 0.8 -0.3 2.1 3.0 0.4 1.4 1.4 1.3 1.8 1.1 1.6 1.4 1.5 1.1 1.3 1.7 -3.0 1.7 1.3 1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 5.5 1.5 -2.0 -1.6 -0.8 0.2 -0.6 0.5 -1.1 -0.6 -0.8 -1.0 0.2 -2.4 -1.0 -1.3 -1.0 -1.0 -0.6 -0.9 -0.6 -0.9 -1.0 -0.7 -1.6 -0.9 -0.6 -0.3 -1.2 1.0 1.4 -0.7 -1.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 1.4 -0.4 -0.1 0.8 0.1 0.5 -0.3 1.2 0.7 -0.3 -0.1 -0.1 -0.1 0.9 0.4 0.7 0.7 0.5 -0.4 -0.3 -0.3 -0.2 -0.1 -0.2 -0.2 -0.1 -0.2 -0.0 -0.1 0.1 -0.7 -0.3 0.4
Qualifications: None of the above 0.3 0.7 4.7 -1.3 -0.7 -0.5 -0.2 -0.3 1.1 -2.2 -0.2 -0.1 0.9 -0.1 0.5 -0.8 -0.3 0.1 0.1 0.9 0.3 0.9 1.2 0.5 1.2 1.0 0.0 0.8 1.0 1.0 0.7 -0.5 0.2 1.2 0.8
Financial difficulties in last 2 years 0.5 0.7 2.0 -0.6 0.5 1.2 0.9 -0.5 0.1 1.2 0.4 0.2 0.9 1.0 0.9 0.3 -0.5 1.2 0.6 0.7 1.4 0.9 0.5 1.1 0.9 0.5 0.9 0.6 1.1 0.8 0.8 -1.1 0.7 0.5 1.2
Mouth/teeth dental problems 0.4 0.6 5.7 0.2 0.0 0.4 0.8 -0.8 -0.4 0.3 0.0 0.1 -0.9 -0.1 0.0 0.7 1.3 0.5 -2.4 -0.6 -1.2 -0.6 -0.5 -0.5 -0.8 -0.5 -0.2 -0.4 -1.3 -0.5 -0.2 -0.0 0.8 -0.6 -1.7
Heart attack 0.5 0.6 3.1 0.0 -0.4 1.3 1.0 -0.4 -0.9 1.8 0.5 -0.1 -0.3 0.8 -0.3 0.3 0.8 -1.2 -0.6 0.5 -1.1 -0.8 -1.0 -0.9 -0.1 -0.7 -0.5 -0.3 -0.7 -1.0 -0.1 -0.3 -1.2 -0.9 0.0
Allergy 1.2 2.7 10.5 1.0 -2.2 -3.2 -3.1 1.7 1.6 -3.0 -1.6 -1.5 0.5 -2.7 -2.1 -2.1 -1.0 -1.3 0.1 0.1 1.8 1.1 1.5 0.7 0.0 0.9 -0.6 0.6 1.3 2.0 -0.7 1.3 1.7 1.2 1.2
Pain all over the body in last month 1.5 1.6 6.2 1.2 0.8 0.1 0.2 0.8 -1.4 1.3 -0.5 -0.7 -1.4 -0.4 0.5 0.3 0.3 -1.5 -1.2 -1.8 -1.6 -1.5 -1.3 -1.3 -1.3 -1.3 -0.4 -1.6 -1.7 -2.2 -1.2 1.2 -2.5 -1.3 -0.7
Diabetes (self-reported) 0.2 0.3 2.3 0.3 -0.5 -0.6 -0.5 0.3 0.2 -0.8 -0.3 -0.8 -0.2 -0.3 0.7 -0.6 -0.2 0.0 -0.1 -0.5 -0.3 -0.1 0.2 0.2 0.1 0.1 -0.1 -0.2 0.4 -0.1 -0.3 0.5 -1.3 0.1 1.5
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.7 1.0 1.2 0.6 -0.1 0.3 -1.5 1.7 -0.5 -0.8 -1.2 -0.6 0.1 0.7 1.0 0.3 -1.5 -1.0 -1.5 -1.5 -1.5 -1.7 -1.1 -1.4 -0.7 -0.8 -1.9 -1.5 -0.9 0.8 0.2 -1.4 -1.5
Medication: Ramipril 2.2 2.8 7.8 2.7 -1.6 -1.6 -0.8 2.5 -1.5 -0.1 -2.3 -1.2 -1.8 -1.1 2.6 -1.0 -0.6 -2.0 -2.8 -1.4 -0.8 -1.4 -1.8 -1.5 -1.0 -2.0 -1.4 -1.7 -0.7 -1.3 -1.8 2.8 -0.4 -1.8 -0.5
Medication: Simvastatin 0.3 0.5 4.1 0.1 0.9 1.0 1.0 0.2 0.4 0.4 0.6 0.4 0.7 0.6 2.0 0.3 0.4 -0.3 -0.5 0.7 0.0 0.3 0.4 0.2 1.1 0.6 0.6 1.0 0.4 0.1 0.7 -0.4 0.3 0.5 1.2
Fluid intelligence score 0.3 0.7 5.8 -0.9 -0.2 1.7 -0.3 -1.3 0.1 1.0 1.4 0.4 0.4 0.3 -2.4 1.2 0.3 0.7 1.6 0.6 -0.4 0.1 0.0 0.1 0.2 0.3 -0.4 0.5 0.4 0.6 0.2 -0.4 0.4 0.2 0.6
Illnesses of siblings 0.3 0.5 1.4 0.7 -0.1 -0.9 -1.1 -0.7 -0.4 -0.2 0.1 0.4 -1.2 -0.5 -0.2 -0.1 -1.2 0.8 -0.1 0.5 -0.6 -0.3 -0.0 -0.4 -1.1 -0.5 -0.4 -1.2 -0.9 -0.6 -0.8 0.4 0.7 -0.4 -1.1
Neuroticism score 1.0 2.0 7.6 -2.6 0.1 1.3 0.5 -0.7 1.3 -0.3 1.6 0.2 1.6 0.7 -0.3 1.0 1.6 0.1 1.3 1.0 1.2 1.6 1.2 1.7 1.7 1.3 0.2 1.6 2.6 2.8 1.4 -1.2 -0.3 1.3 2.3
Weight 0.6 2.7 7.6 -2.6 0.4 0.2 1.4 -2.1 1.6 -0.6 1.9 0.7 1.5 2.1 -1.5 -0.2 -0.1 2.5 2.4 -0.1 1.2 1.7 1.8 2.1 1.7 1.9 1.2 1.2 1.8 1.3 1.7 -2.8 0.1 1.7 2.3
Impedance of arm (right) 0.3 1.2 6.0 1.3 0.2 0.4 -1.0 1.4 -0.8 0.0 -0.9 -0.6 -0.9 -1.9 2.4 1.8 1.1 -1.7 -1.2 1.3 -0.7 -0.5 -0.8 -1.0 -0.7 -1.1 -0.5 -0.0 -0.8 0.6 -0.6 1.5 1.5 -0.8 -1.2
Arm fat percentage (right) 0.2 0.7 2.9 -1.4 -1.7 -1.7 0.1 -0.3 0.4 -1.2 -0.2 -0.7 -0.1 -0.2 0.4 -1.4 -0.2 0.8 -0.9 -0.4 0.0 0.6 0.6 0.6 0.5 0.4 -1.0 -0.0 0.9 1.4 0.0 -1.0 0.4 0.4 0.9
Trunk fat-free mass 0.6 3.4 15.6 -2.4 1.6 1.1 0.9 -2.4 1.7 0.4 2.5 0.8 1.7 2.2 -3.5 0.6 0.0 2.0 3.9 -0.8 1.2 1.5 1.7 1.8 1.4 2.0 1.6 1.6 1.2 0.9 1.9 -3.0 -0.4 1.7 1.6
Hip circumference 0.5 1.9 7.1 -2.2 -0.7 -0.3 1.0 -1.8 1.1 -0.6 1.3 0.8 1.1 1.9 -2.1 -1.1 -0.8 2.7 1.2 -0.3 1.2 1.4 1.4 1.6 1.4 1.4 0.5 0.8 1.5 1.1 1.3 -2.5 0.6 1.3 1.6
Time employed in main current job 0.9 1.0 3.8 0.4 -0.1 -0.2 -0.8 1.0 -1.1 0.1 -1.1 0.1 -1.0 -0.8 0.1 -0.1 -0.2 -1.2 -1.1 -1.0 -1.9 -1.5 -1.4 -1.4 -0.7 -1.2 -1.6 -0.8 -1.2 -0.8 -0.9 1.1 -0.9 -1.3 -1.0
Alcohol intake versus 10 years previously 0.7 1.1 8.4 0.9 0.5 0.3 0.8 0.0 -1.4 2.9 -0.5 -0.8 -0.9 0.1 -0.7 -0.1 0.6 -0.4 -1.8 -1.3 -0.7 -1.0 -1.5 -0.8 -1.1 -1.2 -0.6 -1.2 -1.1 -1.0 -0.8 -0.1 0.6 -1.3 -1.0
Father’s age at death 0.7 1.0 3.1 1.2 -0.8 -1.2 -1.4 0.7 -0.1 -1.1 -0.6 0.3 -0.6 -0.8 -1.7 -1.1 -1.4 -1.8 1.0 -1.2 -1.2 -0.9 -0.1 -1.1 -0.4 -0.2 -0.6 -0.5 -1.1 -1.6 -0.7 1.0 -1.0 -0.2 0.4
Worrier / anxious feelings 0.5 1.0 3.6 -1.7 -1.2 0.3 0.1 0.0 0.9 -0.8 0.6 -0.5 0.7 0.4 1.6 -0.2 0.9 -1.4 0.6 0.9 0.1 1.1 1.0 0.6 1.5 0.8 -0.6 1.1 1.9 1.7 0.8 -0.0 -0.4 0.9 1.9
Frequency of tiredness / lethargy in last 2 weeks 1.5 2.5 9.2 -1.7 1.8 3.0 1.9 -0.8 0.9 0.5 2.4 0.1 1.8 1.7 -0.7 2.4 1.6 0.3 2.2 1.9 0.7 1.2 0.9 1.0 2.0 1.3 1.4 2.0 1.4 1.2 2.0 -1.5 -0.9 1.2 1.6
Falls in the last year 1.3 1.7 4.7 -1.0 1.2 0.6 0.7 -0.6 1.4 0.0 1.0 -0.0 1.7 0.5 0.3 0.8 1.1 -0.1 0.8 1.5 1.9 1.8 1.4 1.5 1.5 1.4 1.4 1.8 1.7 1.8 1.4 -1.3 1.6 1.5 2.2
Hair/balding pattern: Pattern 3 3.0 4.4 11.6 2.0 -3.4 -2.4 -2.5 2.5 -1.4 -0.3 -3.0 -2.3 -1.9 -2.4 -1.6 -2.7 -1.2 -2.2 -2.2 -2.1 -1.8 -1.8 -1.5 -2.3 -1.6 -1.7 -3.3 -1.7 -1.0 -1.0 -2.5 3.0 -0.7 -1.6 -1.1
Number of live births 0.6 0.9 2.9 -0.3 -0.5 -1.1 -1.5 0.3 -1.2 0.7 -0.7 -0.9 -0.8 -0.8 -0.7 -1.0 -1.6 -1.3 -0.3 -1.4 -0.8 -0.9 -1.0 -0.9 -0.9 -1.0 -1.7 -0.7 -0.4 0.1 -0.9 0.0 0.7 -1.0 -1.1
Forced expiratory volume in 1-second (FEV1) 1.8 5.9 15.1 -3.3 0.8 2.3 2.1 -3.6 2.1 1.5 3.9 3.5 2.2 3.1 -3.2 0.8 0.3 2.1 3.5 1.9 2.0 2.1 1.9 2.4 2.0 2.5 1.4 2.5 1.8 2.0 2.5 -3.8 2.2 2.0 1.8
Pulse rate 1.8 3.1 6.4 2.4 -1.5 -2.5 -1.7 2.1 -1.5 -0.2 -2.4 -1.1 -2.2 -1.6 -1.4 -2.3 -1.7 -1.7 -1.2 -2.5 -0.6 -1.6 -1.3 -1.5 -2.1 -1.8 -1.1 -2.1 -1.7 -2.1 -2.1 1.6 -0.9 -1.7 -1.1
Happiness 1.5 1.8 4.1 -1.9 -1.1 0.6 0.8 -0.6 1.6 -1.5 1.4 -1.0 1.1 0.6 0.1 0.4 1.3 -0.8 1.7 1.6 1.2 1.7 2.0 1.3 1.6 1.5 0.6 1.6 1.6 1.9 1.4 -1.0 0.7 1.7 1.8
Noisy workplace 0.4 0.4 2.3 -0.8 0.4 -0.2 0.3 0.2 0.5 0.1 0.2 -1.3 0.4 -0.5 1.5 0.3 0.7 1.0 -1.2 -0.9 -0.2 0.6 0.6 0.4 0.0 0.4 -0.0 0.2 0.4 1.1 0.2 -0.9 1.0 0.5 -0.0
Qualifications: A levels/AS levels or equivalent 0.6 1.4 4.3 2.0 0.4 -0.2 -0.9 0.2 -1.2 1.1 -0.3 -1.6 -1.5 -0.7 -2.1 0.7 -0.7 -0.6 0.2 -1.4 -1.2 -1.5 -1.3 -1.6 -1.3 -1.4 -0.1 -0.8 -2.0 -1.8 -0.9 0.8 -1.3 -1.4 -0.8
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 3.0 0.9 1.0 0.2 -0.0 0.9 -0.3 0.5 -0.1 0.7 -0.1 -0.7 1.7 0.8 0.9 -0.6 0.5 -0.1 0.0 -0.4 -0.5 -0.4 -0.1 -0.3 -0.1 0.3 -0.2 0.2 -0.2 0.7 -0.1 -0.3 0.1
Mouth/teeth dental problems: Dentures 1.2 2.0 8.1 -0.3 -0.3 -0.6 -0.6 -0.6 1.5 -0.7 0.2 -0.4 2.0 0.3 -0.4 -1.6 -1.4 0.2 2.6 1.2 2.8 1.6 1.6 2.0 1.0 1.8 1.2 1.2 2.3 1.4 0.7 -0.6 1.5 1.8 2.3
Asthma 0.8 1.6 8.8 0.4 0.6 1.6 1.7 -0.6 -1.6 3.0 0.1 0.5 -1.1 1.4 1.0 0.2 -0.4 0.5 -0.7 -1.3 -1.1 -1.5 -2.1 -0.9 -1.2 -1.3 -0.3 -1.5 -1.7 -1.8 -0.5 -0.9 -0.1 -1.7 -1.9
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 3.1 -1.4 -1.3 -0.3 -0.7 -0.0 -0.8 0.0 -0.4 0.5 -0.7 -0.4 0.6 -0.6 -0.5 0.2 -1.0 0.7 -1.1 -0.5 -0.7 -0.6 -0.1 -0.7 -1.8 -0.7 0.0 0.5 -0.5 -0.1 0.1 -0.7 -0.1
Medication: Cholesterol lowering 0.2 0.3 2.1 0.8 0.7 0.1 0.6 0.2 -0.2 0.6 -0.0 1.0 0.1 0.5 1.4 -0.2 -0.0 -1.1 -0.6 -0.4 -0.2 0.2 -0.1 -0.1 0.4 -0.0 0.1 -0.1 0.2 -0.4 0.1 -0.2 -1.3 -0.0 0.9
Depression (self-reported) 0.5 0.5 1.5 -1.2 -0.8 0.9 0.3 -0.8 0.6 -0.1 1.0 0.0 1.0 0.4 0.7 0.3 0.8 0.2 0.3 1.2 -0.1 0.5 0.4 0.4 1.2 0.8 -0.3 1.0 0.9 1.1 0.7 -0.5 0.2 0.6 1.2
Medication: Lansoprazole 0.8 0.9 3.2 -0.2 1.4 0.9 1.8 -0.9 0.3 -0.2 0.5 -0.4 1.1 1.0 1.3 0.8 1.2 1.5 -1.1 0.1 0.3 0.9 0.6 0.7 1.5 0.5 0.9 1.1 1.1 0.9 1.3 -0.7 -0.3 0.7 0.6
Prospective memory result 1.3 1.6 4.8 -1.0 1.4 1.4 2.2 -0.9 1.3 -0.6 1.0 -0.5 1.4 1.8 0.9 0.8 1.6 -1.6 0.6 -0.3 0.3 1.2 1.5 0.9 1.7 1.4 2.0 1.4 0.4 -0.0 1.9 -1.7 -0.2 1.5 0.3
Lung cancer (father) 2.6 3.0 7.5 -1.1 0.7 1.1 1.7 -1.8 2.2 -1.0 1.3 0.8 2.3 1.3 0.8 0.2 0.4 2.7 1.6 2.3 1.8 2.0 2.3 2.0 2.1 2.2 2.2 2.0 1.6 1.2 2.1 -1.6 0.8 2.3 1.9
Illnesses of mother 0.4 0.5 2.1 -0.5 0.5 1.2 0.9 -1.2 0.4 0.8 1.4 0.6 0.4 1.4 0.5 0.9 0.4 -0.3 0.9 0.3 -0.1 0.4 0.4 0.4 0.7 0.6 0.5 0.6 0.3 -0.0 0.8 -0.7 -0.2 0.4 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 2.1 6.5 17.6 -3.3 1.5 3.2 2.7 -3.5 2.1 1.7 4.2 4.0 2.3 3.3 -3.4 1.6 1.1 1.2 3.9 2.2 1.7 1.9 1.8 2.0 2.1 2.5 1.9 2.8 1.3 1.4 2.8 -3.7 1.9 2.0 1.7
Pulse wave Arterial Stiffness index 0.3 0.4 2.8 -0.1 -0.5 0.4 0.8 -0.4 -0.0 0.0 -0.1 0.4 -0.2 0.4 1.3 -0.5 -0.1 1.7 -0.8 0.4 -0.7 -0.1 -0.1 -0.2 0.4 -0.0 -0.3 -0.5 -0.1 -0.8 -0.1 0.1 -1.3 -0.1 0.9
Impedance of arm (left) 0.2 1.0 8.1 0.7 1.4 1.6 0.1 0.5 -0.1 0.2 0.1 0.2 0.0 -0.9 2.8 2.7 1.6 -0.8 -0.5 2.0 -0.1 0.2 -0.1 -0.1 0.2 -0.3 0.7 0.7 -0.2 0.9 0.3 0.7 1.2 -0.1 -0.4
Arm fat mass (right) 0.3 1.1 4.8 -2.2 -0.8 -0.7 0.9 -1.2 1.0 -1.1 0.9 -0.2 0.7 1.0 -0.2 -0.9 -0.0 1.7 0.5 -0.2 0.5 1.1 1.2 1.2 1.1 1.2 0.0 0.6 1.3 1.3 0.9 -2.0 0.2 1.0 1.5
Trunk predicted mass 0.5 3.1 14.2 -2.3 1.5 1.0 0.8 -2.4 1.6 0.4 2.4 0.8 1.6 2.2 -3.5 0.5 -0.1 2.0 3.8 -0.9 1.2 1.4 1.6 1.7 1.3 1.9 1.4 1.5 1.1 0.9 1.8 -3.0 -0.3 1.6 1.5
Standing height 0.8 7.6 40.1 -2.0 4.2 3.7 1.4 -2.6 2.3 0.9 3.8 1.9 2.7 2.8 -2.8 3.8 1.0 2.5 6.3 1.2 2.0 2.3 2.1 2.6 2.3 2.6 3.8 2.7 1.6 1.2 3.0 -3.0 0.1 2.4 2.6
Length of working week for main job 0.4 0.5 1.9 0.1 0.5 1.1 0.5 0.6 -0.9 1.4 0.4 -0.5 -0.3 0.2 -0.9 0.3 1.1 -0.5 -0.1 -0.0 -0.6 -1.0 -1.0 -0.6 -0.6 -0.6 -0.2 -0.4 -0.4 -0.9 -0.4 0.6 -0.9 -0.8 -0.2
Exposure to tobacco smoke at home 0.5 0.6 2.7 -1.0 -0.8 0.7 1.0 -0.7 0.3 1.4 0.8 -1.4 0.4 1.3 1.6 -0.3 0.2 -0.1 1.2 -0.2 0.1 0.7 0.3 0.5 0.5 0.5 -0.4 0.1 0.7 0.5 0.5 -0.7 -0.6 0.3 0.2
Breastfed as a baby 0.3 0.3 2.8 0.1 0.9 0.0 0.4 -0.2 -0.2 -0.1 0.5 0.2 -0.4 0.8 1.1 0.2 -0.0 -1.7 0.3 -1.2 -0.8 -0.4 -0.2 -0.4 0.4 -0.2 0.2 0.1 -0.7 -0.9 0.4 -0.4 -0.5 -0.3 0.1
Tense / ‘highly strung’ 0.3 0.5 1.9 -0.1 0.1 0.4 -0.6 0.8 -0.9 1.0 -0.8 -1.2 -0.3 -0.8 -0.5 0.5 1.0 -0.9 0.3 -1.0 -0.3 -0.1 -0.5 -0.0 -0.5 -0.7 -0.7 -0.8 0.6 0.5 -0.7 1.1 -1.4 -0.5 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.6 4.7 -2.0 -0.7 0.2 0.5 -1.0 1.4 -0.8 0.9 -1.1 1.7 0.9 0.7 -0.7 0.6 -0.2 0.9 0.1 0.9 1.5 1.4 1.6 2.0 1.4 0.0 1.2 2.2 2.2 1.3 -1.7 0.5 1.5 2.1
Hair/balding pattern: Pattern 4 2.8 6.7 14.9 1.6 -0.0 -0.8 -1.3 1.9 -3.8 2.8 -2.1 -1.1 -3.7 -1.2 -0.3 -0.5 -0.8 -1.8 -2.5 -3.0 -2.9 -3.4 -3.8 -3.1 -3.1 -3.8 -2.7 -3.6 -3.3 -3.0 -2.9 1.6 -1.2 -3.9 -3.0
Birth weight of first child 2.3 4.3 9.3 -1.0 1.8 2.2 1.8 -2.3 2.5 -0.9 2.0 2.2 2.5 1.9 0.4 1.4 0.6 1.6 2.6 2.8 2.1 2.3 2.7 2.4 2.1 2.6 3.0 2.4 1.6 1.0 2.4 -1.9 0.8 2.7 2.0
Peak expiratory flow (PEF) 1.6 3.7 11.5 -3.2 0.4 2.3 2.5 -2.9 1.4 1.7 3.4 1.2 1.4 3.1 -2.8 1.0 1.1 1.2 2.7 1.2 0.9 1.4 1.2 1.6 1.5 1.8 1.3 1.8 0.8 0.7 2.1 -3.1 1.7 1.3 1.4
Pulse wave reflection index 0.4 0.5 2.4 0.3 -0.2 0.8 0.6 -0.1 -0.8 1.0 -0.4 -0.3 -0.5 0.2 0.5 0.1 -0.1 1.0 -0.7 0.3 -1.6 -0.7 -0.9 -1.0 0.2 -0.8 -1.0 -1.0 -0.8 -1.0 -0.3 0.3 -0.8 -0.8 -0.1
Ever highly irritable/argumentative for 2 days 0.4 0.5 4.2 -0.5 -2.0 -0.7 0.0 -0.3 -0.7 0.7 -0.2 -0.9 -0.5 -0.2 -0.2 -1.3 0.0 0.0 -1.1 -0.3 -1.0 -0.5 -0.3 -0.7 -0.2 -0.5 -1.5 -0.6 -0.2 0.0 -0.4 -0.3 -0.3 -0.5 -0.8
Loud music exposure frequency 0.6 0.7 2.6 1.4 0.5 -0.5 -0.7 1.6 -0.8 -0.1 -1.1 -1.1 -0.8 -1.3 0.6 0.7 0.5 -1.4 -0.4 -1.0 0.0 -0.8 -0.8 -0.3 -0.9 -1.0 0.4 -0.5 -0.8 -0.2 -0.7 0.7 -0.5 -0.8 -0.7
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 2.2 0.6 -0.4 -0.3 0.2 -0.1 -0.5 0.7 -0.2 0.1 -0.8 0.4 -0.7 -0.3 -0.6 0.2 -0.0 -0.9 -0.3 -0.4 -0.4 -0.2 -0.7 -0.5 0.0 -1.0 -0.6 -1.1 -0.5 0.2 -1.5 -0.6 0.0
Mouth/teeth dental problems: Bleeding gums 0.4 0.6 3.1 -0.4 0.1 -0.0 -0.2 0.6 -1.0 0.5 0.1 0.1 -1.0 0.1 -1.0 0.2 -0.1 -0.5 1.2 -0.4 -1.2 -0.9 -0.9 -1.0 -0.2 -1.0 -0.8 -0.7 -1.0 -0.6 -0.2 -0.4 -1.8 -1.0 -0.7
Blood clot in the leg (DVT) 1.1 1.4 4.3 -0.5 -0.4 0.9 1.8 -1.2 1.2 -0.8 0.9 1.6 1.4 1.4 0.1 0.3 0.6 1.2 0.6 2.1 1.4 1.2 1.4 1.3 1.7 1.3 1.4 1.3 1.3 0.3 1.4 -0.6 -0.3 1.4 1.7
Medication: Paracetamol 0.6 1.0 3.3 -1.8 0.2 1.6 1.4 -0.7 0.4 1.4 0.8 0.2 1.2 1.2 0.7 0.7 1.6 0.1 -0.5 0.9 0.8 1.1 0.3 0.9 1.1 0.6 0.1 1.1 1.5 1.6 1.1 -1.5 0.6 0.5 0.5
Headache pain in last month 0.3 0.5 2.4 -1.1 0.6 1.3 0.8 -0.2 -0.1 0.1 0.7 0.5 0.5 0.1 0.4 0.8 0.9 -0.8 0.7 1.5 0.2 0.3 0.2 0.4 0.6 0.1 -0.1 0.5 0.8 0.8 0.4 -0.5 -0.7 0.2 1.5
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 6.0 -0.7 -1.0 -0.3 -0.6 -0.7 0.5 -0.0 0.4 -0.3 0.1 0.2 -1.2 -0.7 -0.8 1.1 1.7 0.5 1.1 0.3 0.4 0.6 -0.4 0.4 0.0 0.2 0.2 0.5 0.0 -0.4 2.4 0.3 -0.4
Glaucoma (self-reported) 1.4 1.6 8.5 2.2 -0.9 -1.1 -1.5 1.7 -0.8 -0.2 -1.8 -0.2 -0.6 -0.6 -1.1 -2.1 -2.9 -0.3 -0.4 -0.9 -0.2 -1.2 -0.7 -1.0 -0.9 -0.9 0.0 -1.3 -1.2 -2.4 -1.2 1.6 1.1 -0.7 -0.3
Gout (self-reported) 0.6 0.9 2.4 0.5 0.9 0.7 0.2 0.2 -1.5 1.0 -0.2 1.1 -1.0 -0.4 0.4 0.8 0.8 -0.5 -0.5 0.0 -1.5 -1.3 -1.6 -1.4 -0.7 -1.3 -1.2 -0.7 -1.3 -0.7 -0.6 0.0 0.3 -1.4 -1.1
Hypothyroidism/myxoedema (self-reported) 2.6 5.1 8.7 -2.5 1.3 2.2 2.9 -2.7 2.8 -1.7 2.9 2.5 2.5 2.5 2.2 1.9 2.0 1.5 0.4 2.3 0.9 2.3 2.6 2.0 2.9 2.8 2.3 2.5 2.0 1.3 2.8 -2.1 -0.5 2.6 2.6
Medication: Amlodipine 2.2 3.0 6.9 2.5 1.2 0.5 -0.7 1.8 -2.2 1.0 -1.3 -1.4 -1.5 -1.7 1.5 1.1 0.7 -2.4 -1.9 -1.3 -2.3 -2.4 -2.3 -2.6 -1.2 -2.2 -1.1 -1.2 -2.2 -1.8 -1.4 1.4 -2.1 -2.1 -1.5
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.7 1.1 0.1 -0.2 -0.4 0.8 -1.4 1.5 -1.2 -0.9 -0.8 -0.3 -0.0 -0.5 -1.2 -0.6 0.3 -1.6 -0.7 -1.1 -1.5 -0.8 -1.1 -1.2 -0.6 -1.2 -0.7 -0.9 -0.9 0.5 0.9 -1.2 -1.2
Birth weight 1.0 2.2 7.9 -0.9 0.8 0.2 0.1 -1.2 1.9 -2.0 0.8 0.7 1.8 0.2 -0.2 0.3 0.2 2.2 2.0 2.8 2.2 1.5 1.9 1.8 1.3 1.8 2.1 1.7 1.2 1.2 1.4 -1.1 1.5 1.9 1.2
Chronic bronchitis/emphysema (mother) 0.3 0.3 2.3 0.9 0.7 -0.0 -0.9 0.6 -0.1 -0.1 -0.3 -1.5 -0.0 -0.9 -0.7 0.5 0.3 -1.2 0.7 -1.1 -0.2 -0.3 -0.1 -0.3 -0.6 -0.2 0.1 0.1 -0.3 -0.0 -0.3 0.3 0.2 -0.1 -0.7
High blood pressure (siblings) 0.4 0.5 2.1 -0.5 0.8 1.0 1.1 0.5 0.6 -0.5 0.0 0.7 0.9 0.1 0.9 0.8 1.4 -0.4 1.1 -0.1 0.3 0.2 0.0 0.2 1.1 0.4 0.2 1.3 0.8 0.9 0.7 -0.1 -0.8 0.3 1.0
Forced vital capacity (FVC), Best measure 1.5 5.5 18.0 -2.7 2.1 3.1 2.3 -3.5 1.6 1.9 3.7 4.2 1.9 3.1 -3.8 1.7 0.4 1.7 3.6 1.1 1.4 1.5 1.4 1.8 1.6 2.0 2.0 2.1 0.9 0.9 2.4 -3.5 1.6 1.6 1.4
Body fat percentage 0.4 1.4 4.4 -2.1 -0.8 -0.3 1.1 -1.1 1.2 -1.0 0.8 -0.4 1.0 1.0 0.8 -0.6 0.2 1.5 0.7 0.2 0.9 1.4 1.4 1.6 1.4 1.3 0.4 0.8 1.8 1.7 1.1 -1.8 0.8 1.3 1.9
Leg fat percentage (right) 0.4 1.5 3.9 -2.0 -1.6 -0.8 0.5 -1.0 1.3 -0.7 0.6 -1.4 1.1 0.9 0.2 -1.6 -0.3 1.1 1.0 -0.3 0.9 1.4 1.5 1.5 1.3 1.4 -0.1 0.6 1.9 1.6 0.8 -1.5 0.9 1.4 1.8
Arm fat-free mass (right) 0.9 4.6 16.1 -2.5 1.9 1.9 2.2 -2.8 1.8 0.6 3.0 1.6 2.1 3.2 -3.1 0.7 0.3 2.8 4.0 -0.1 1.5 1.6 1.8 2.2 1.9 2.3 2.4 1.7 1.4 0.4 2.3 -3.2 -0.6 2.0 2.1
Exposure to tobacco smoke outside home 0.7 0.9 8.1 -1.1 0.3 2.2 1.5 -1.0 -0.2 2.9 1.2 -0.0 0.6 1.7 -1.8 0.1 0.3 0.6 1.2 0.5 -0.1 0.3 0.2 0.4 0.0 0.4 0.4 0.1 -0.1 -0.5 0.6 -0.8 0.8 0.3 -0.3
Comparative body size at age 10 1.1 3.0 8.8 -2.0 -0.9 0.3 1.4 -1.8 2.0 -1.4 1.8 2.2 1.8 1.5 1.8 -0.3 0.6 2.5 -0.4 1.8 0.7 1.9 2.0 1.6 2.7 2.0 0.2 2.1 2.4 2.2 1.8 -1.4 -0.4 1.9 3.0
Number of full brothers 0.5 0.6 1.8 -0.9 0.4 -0.2 -0.2 -0.8 1.1 -0.2 0.8 0.5 0.5 -0.1 0.9 0.4 -0.3 1.2 1.1 0.6 1.3 1.0 1.1 1.3 -0.4 1.0 0.7 0.1 0.6 1.1 0.2 -1.0 -0.1 0.9 0.1
Worry too long after embarrassment 0.7 1.2 4.3 -0.8 0.6 1.1 0.9 0.1 1.1 -0.7 1.1 0.1 1.5 1.0 -0.8 1.0 0.8 0.9 1.4 1.3 0.9 1.0 1.1 0.6 1.9 1.1 0.9 2.1 1.4 1.1 1.6 -0.5 0.4 1.2 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 1.0 4.3 -0.9 0.3 0.4 0.6 -0.9 1.1 -0.3 0.8 0.6 1.2 0.6 -0.1 -0.0 0.5 0.7 0.2 0.2 1.0 1.3 0.9 1.4 1.5 1.1 0.1 0.9 1.9 2.0 0.9 -0.7 0.4 1.0 2.1
Wheeze or whistling in the chest in last year 0.4 0.7 3.2 -0.3 1.8 0.9 0.6 -0.5 0.5 0.5 0.4 0.4 0.5 0.4 1.7 1.0 0.1 -0.7 1.8 -0.5 1.0 0.8 0.6 1.0 -0.1 0.7 1.5 0.3 0.4 0.3 0.6 -0.5 -0.4 0.6 -0.4
Number of children fathered 1.0 1.2 3.5 -0.2 -0.6 -1.1 -0.9 -0.1 1.4 -1.6 -0.3 -0.1 0.8 -0.3 -1.3 -0.4 -1.5 1.8 0.7 0.3 1.8 1.4 1.3 1.6 0.5 1.1 1.0 0.7 1.2 1.5 0.6 -0.4 1.9 1.2 0.4
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 5.9 0.7 -0.4 -1.2 -0.9 0.6 -1.4 0.2 -1.8 0.8 -1.3 -1.2 0.2 -1.9 -0.9 -0.2 -2.4 -2.0 -1.2 -1.2 -1.2 -0.9 -1.0 -1.3 -1.9 -1.5 -0.5 -0.4 -1.4 0.7 -0.8 -1.2 -0.9
Age at first live birth 1.0 1.8 5.6 2.2 0.1 -0.4 -1.3 1.1 -1.2 -0.6 -1.1 1.2 -1.6 -1.4 -0.0 0.2 0.1 -1.4 -0.5 -1.2 -2.4 -1.6 -1.2 -2.0 -1.2 -1.5 -1.2 -1.3 -1.8 -1.7 -1.4 1.7 -1.4 -1.4 -0.8
Pulse wave peak to peak time 0.4 0.5 2.8 -0.0 0.7 -0.1 -0.8 0.1 0.2 0.1 0.3 -0.4 0.4 -0.2 -1.7 0.6 -0.0 -1.5 1.3 -0.3 1.0 0.3 0.3 0.5 -0.2 0.2 0.6 0.7 0.3 0.9 0.3 -0.3 1.4 0.3 -0.6
Health satisfaction 0.3 0.4 5.6 -0.7 -0.6 0.0 0.5 0.4 0.0 -0.2 0.2 -2.4 0.3 0.1 0.5 0.0 1.3 -0.4 0.5 0.5 0.3 0.3 0.3 0.0 0.6 0.0 -0.3 0.5 0.4 0.9 0.5 -0.5 0.9 0.2 -0.0
Shortness of breath walking on level ground 0.7 0.8 3.9 -0.3 -0.0 0.1 0.1 0.2 1.0 -0.6 -0.1 0.3 1.3 -0.2 1.4 -0.1 0.8 0.5 0.5 2.0 1.6 0.9 0.8 0.9 0.9 0.7 0.7 0.8 1.2 1.3 0.6 -0.1 1.8 0.9 0.3
Qualifications: College or University degree 3.0 9.3 20.3 4.0 -1.1 -1.7 -3.1 2.4 -3.7 2.8 -3.0 -2.1 -3.7 -1.9 -2.5 -1.7 -2.7 -1.7 -0.9 -4.5 -3.3 -3.7 -3.6 -3.6 -3.3 -3.8 -3.1 -3.7 -3.5 -3.6 -3.5 3.0 -0.9 -3.8 -3.0
Eye problems/disorders: None of the above 1.3 1.5 5.7 -0.9 0.0 0.7 0.5 -0.8 1.6 -0.5 1.4 0.3 1.5 0.9 0.7 0.6 0.7 -0.5 1.8 1.3 1.0 1.7 1.5 1.3 1.6 1.5 0.5 1.5 1.9 1.7 1.3 -0.6 0.6 1.5 2.4
Mouth/teeth dental problems: Loose teeth 0.9 1.0 2.4 -1.2 1.1 1.1 0.9 -1.2 1.0 -0.2 0.9 1.5 1.2 1.2 0.3 0.4 0.4 1.5 1.4 0.6 0.2 1.1 1.0 0.9 1.4 1.1 0.9 1.0 1.0 0.8 1.3 -1.3 -0.2 1.1 0.8
Emphysema/chronic bronchitis 2.4 2.7 7.6 -2.7 0.3 1.2 1.1 -2.2 1.7 -0.6 2.0 0.5 1.7 1.7 1.8 1.2 0.2 2.1 2.0 1.8 1.0 2.0 1.9 2.3 1.6 1.9 1.5 1.0 1.9 1.6 1.7 -2.0 -0.1 1.8 1.5
Medication for pain relief, constipation, heartburn 0.3 0.5 2.6 1.5 0.5 -0.3 -0.9 0.4 0.3 -1.6 -0.3 -0.0 -0.1 -0.9 -0.7 0.4 -0.1 0.9 1.2 0.2 0.3 -0.3 0.4 -0.3 -0.2 0.0 0.8 0.2 -0.8 -0.7 -0.2 1.2 -0.6 0.2 -0.5
Neck or shoulder pain in last month 2.3 3.3 7.3 -1.7 0.6 1.7 1.3 -1.0 2.3 0.0 1.7 0.2 2.7 1.4 -1.4 0.3 0.9 -0.3 2.1 1.5 2.2 2.2 2.3 2.2 2.2 2.4 1.8 2.5 2.6 2.1 2.0 -1.8 0.6 2.5 2.4
Medication: Blood pressure 0.4 0.7 6.0 0.3 1.0 0.5 0.9 0.1 -0.1 -0.4 -0.2 0.4 0.1 0.0 2.0 0.5 0.9 -1.1 -1.8 -0.4 -1.3 -0.2 -0.3 -0.4 0.6 -0.1 -0.0 0.0 -0.1 -0.3 0.2 0.1 -2.4 -0.1 0.5
Angina (self-reported) 1.0 1.3 5.2 0.3 1.1 0.5 -0.2 0.4 1.1 -1.0 0.2 1.4 1.3 -0.6 1.7 0.9 1.5 0.2 0.7 2.3 1.6 1.1 0.8 0.8 1.0 0.9 0.6 1.3 1.4 1.5 0.5 0.3 1.5 1.0 2.1
Migraine (self-reported) 3.6 4.4 10.9 2.9 -1.6 -2.7 -1.9 3.2 -2.0 0.1 -2.9 -2.1 -2.0 -2.7 1.2 -1.3 0.4 -2.3 -3.0 -1.6 -1.1 -1.8 -1.9 -2.2 -2.1 -2.3 -2.3 -2.1 -1.4 -1.4 -2.6 3.3 -0.5 -2.1 -1.3
Medication: Ibuprofen 0.4 0.4 2.3 -1.1 -1.4 -0.7 -0.5 -0.0 -0.5 0.3 -0.6 0.0 -0.5 -0.3 0.5 -0.9 -0.5 0.9 -0.7 0.7 -0.5 -0.2 -0.5 -0.3 -0.0 -0.6 -1.5 -0.7 0.2 0.6 -0.5 -0.1 1.0 -0.6 0.1
Medication: Allopurinol 0.6 0.7 4.7 -1.3 0.8 0.9 1.4 -1.6 0.1 0.8 1.3 2.1 0.3 1.2 0.3 0.1 0.5 0.6 -0.1 0.5 -0.3 0.2 -0.1 0.3 0.5 0.3 -0.3 0.4 0.2 0.4 0.7 -2.2 0.9 0.0 0.4
Medication: Omeprazole 0.2 0.2 0.9 -0.4 -0.1 -0.1 0.4 -0.9 0.0 0.5 0.3 0.7 0.3 0.9 -0.5 -0.5 -0.6 0.9 0.3 -0.2 0.1 0.2 0.1 0.3 0.3 0.2 -0.1 -0.1 0.5 0.1 0.3 -0.6 0.7 0.2 0.0
Medication: Seretide 50 evohaler 1.2 1.4 10.6 0.5 2.7 3.3 1.6 0.0 -0.8 1.5 0.7 0.4 0.4 1.1 -0.5 2.5 0.8 -1.0 1.3 0.2 -0.8 -0.8 -0.9 -0.6 0.4 -0.4 1.1 0.4 -0.7 -1.0 0.7 -0.2 -0.9 -0.5 -0.9
Mean time to correctly identify matches 0.1 0.1 1.4 0.5 0.6 -0.4 -0.4 0.3 0.2 -0.5 -0.4 0.1 0.0 -0.4 1.2 -0.4 -0.1 -0.5 -0.2 -0.4 -0.2 -0.0 -0.0 -0.4 0.0 0.1 -0.3 -0.0 -0.1 -0.1 -0.2 0.4 -0.7 0.0 -0.1
Heart disease (mother) 0.3 0.4 1.4 1.2 0.2 -0.8 -0.3 1.1 -0.3 -0.9 -1.1 -1.1 -0.3 -0.7 0.6 -0.4 0.3 -0.1 0.2 -0.5 0.2 -0.3 -0.2 -0.4 -0.4 -0.4 0.1 -0.5 -0.5 -0.4 -0.4 0.5 0.6 -0.2 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.7 1.1 -0.3 -1.1 -1.5 1.4 0.2 -1.1 -1.0 -1.7 -0.1 -1.3 0.4 0.4 -0.2 0.2 -0.1 0.5 0.9 0.3 0.3 0.0 0.4 -0.1 -0.5 0.5 0.9 1.4 -0.2 1.7 -0.2 0.1 -0.1
Whole body fat mass 0.4 1.9 5.9 -2.4 -0.4 -0.1 1.2 -1.5 1.4 -1.0 1.3 -0.2 1.2 1.4 -0.1 -0.4 0.1 1.7 1.6 -0.0 0.9 1.5 1.6 1.8 1.6 1.6 0.7 1.1 1.8 1.6 1.4 -2.3 0.4 1.5 2.1
Leg fat mass (right) 0.4 1.7 4.7 -2.1 -0.9 -0.6 0.7 -1.3 1.5 -0.8 1.0 -0.7 1.2 1.3 -0.4 -1.2 -0.6 1.7 1.6 -0.2 1.1 1.5 1.7 1.7 1.4 1.6 0.5 0.8 1.8 1.3 1.1 -1.9 0.6 1.6 2.2
Arm predicted mass (right) 1.0 5.0 17.1 -2.4 1.9 1.7 2.1 -2.8 2.1 0.3 3.0 1.3 2.3 3.1 -2.8 0.6 0.2 2.9 4.1 0.1 2.0 2.0 2.1 2.5 2.1 2.5 2.6 1.9 1.7 0.9 2.5 -3.3 -0.3 2.2 2.3
Pulse rate, automated reading 0.6 1.8 4.9 2.2 -0.6 -1.8 -2.0 2.0 -1.0 -1.0 -2.1 -0.7 -1.4 -1.8 -1.0 -1.2 -1.6 -0.9 -1.1 -1.3 -0.2 -1.2 -0.7 -1.3 -1.2 -1.3 -0.4 -1.1 -1.2 -1.7 -1.5 1.9 0.1 -0.9 -0.3
Alcohol intake frequency. 0.5 1.2 4.7 0.7 -0.5 -1.5 -0.4 1.0 -1.4 1.3 -1.1 -1.4 -1.0 -0.8 -0.2 -1.3 -0.3 0.2 -2.0 -0.9 -0.8 -1.0 -1.4 -1.1 -1.1 -1.3 -2.2 -1.5 -0.5 -0.3 -1.4 1.1 -0.0 -1.4 -0.9
Comparative height size at age 10 0.8 4.7 24.2 -1.9 2.3 2.0 0.9 -2.3 2.4 -0.3 2.6 0.3 2.3 2.3 -1.5 1.8 0.2 1.7 4.9 0.2 1.3 2.3 2.5 2.1 2.6 2.5 2.7 2.5 1.6 1.2 2.7 -2.4 -0.3 2.5 2.6
Number of full sisters 0.2 0.3 2.3 0.1 0.4 0.5 0.6 0.6 -0.7 1.5 -0.3 -0.1 0.3 0.5 -0.1 -0.4 0.4 -0.5 1.2 -0.0 0.7 -0.4 -0.7 -0.2 -0.1 -0.4 -0.2 -0.1 0.2 -0.4 -0.2 0.8 0.5 -0.4 -0.2
Suffer from ‘nerves’ 0.9 1.4 5.8 -1.0 1.5 2.2 2.1 -1.3 -0.5 1.9 1.7 2.4 0.7 1.8 1.3 0.9 1.4 1.6 0.4 0.3 0.0 -0.2 -0.6 0.1 1.0 0.1 -0.0 0.7 0.4 0.4 1.0 -1.4 -0.1 -0.3 0.2
Overall health rating 1.2 2.6 6.7 -1.5 0.7 1.6 1.7 -1.2 1.3 0.1 1.4 0.4 2.1 1.3 2.2 1.2 1.3 0.9 0.3 1.9 1.7 2.2 1.7 2.0 2.1 1.6 1.4 1.5 2.6 2.1 1.7 -1.2 0.7 1.8 2.5
Chest pain or discomfort 2.3 3.3 8.4 -1.0 2.0 2.5 2.1 -0.9 1.7 0.2 1.8 0.2 2.4 2.2 1.0 2.2 1.4 -0.2 2.9 1.5 1.7 1.9 1.4 1.9 2.4 1.7 2.4 1.6 2.3 0.9 2.1 -1.0 -1.5 1.7 2.9
Had major operations 0.9 1.0 7.7 -1.2 2.8 1.3 1.1 -0.1 0.6 0.2 0.9 -0.2 0.9 0.5 1.3 1.5 1.3 0.4 1.8 0.6 0.6 0.7 0.7 0.8 0.6 0.8 1.3 1.1 0.4 0.6 1.0 -0.8 -0.7 0.8 0.4
Age at last live birth 0.8 1.2 4.6 1.2 1.9 1.3 0.3 0.3 -0.9 0.1 -0.0 1.4 -0.9 -0.2 0.6 1.7 0.6 -2.1 0.5 -0.6 -2.0 -1.1 -1.0 -1.4 -0.4 -0.9 -0.1 -0.4 -1.7 -1.4 -0.1 0.4 -1.7 -0.9 -0.9
Family relationship satisfaction 1.6 2.0 8.7 -0.2 -3.0 -2.0 -2.3 1.8 -0.7 -1.6 -1.5 -2.0 -1.9 -1.5 -1.6 -1.3 -1.6 -1.1 -0.2 -0.8 -1.2 -0.8 -0.5 -1.0 -1.2 -1.1 -2.1 -1.6 -0.9 -0.2 -1.4 1.2 0.7 -1.0 -0.8
Leg pain on walking 0.6 0.8 7.8 1.2 0.4 0.8 1.0 0.6 -1.2 2.8 -0.4 -0.7 -0.2 0.1 -0.8 0.0 0.5 -0.6 -1.9 -0.5 -0.0 -0.7 -1.2 -0.7 -0.4 -0.9 -0.2 -0.2 -0.7 -0.7 -0.4 -0.0 1.4 -0.9 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.4 -0.4 -0.7 -1.2 -0.4 -0.1 0.7 -1.0 -0.2 -0.8 0.4 -0.7 1.2 -0.6 -0.3 0.7 -0.7 0.5 1.5 0.8 0.7 1.2 0.2 0.4 0.2 -0.0 1.3 1.5 -0.0 -0.5 0.9 0.6 1.2
Commuting to job workplace: Car/motor vehicle 1.3 1.5 9.0 -0.4 3.0 1.7 1.9 -0.7 0.6 0.1 1.1 2.3 0.9 0.9 -0.1 1.7 1.1 1.9 1.0 1.6 1.0 0.7 0.8 1.2 0.4 0.8 2.3 0.7 0.3 -0.1 1.0 -0.3 0.8 0.9 0.4
Illness, injury, bereavement, stress in last 2 years 0.8 0.9 3.9 -1.0 -0.1 0.2 0.6 -1.4 1.4 -1.3 1.2 1.1 0.7 1.3 -2.0 0.3 0.2 0.6 0.7 -0.2 -0.0 1.0 1.3 0.8 1.0 1.2 1.1 0.7 0.4 -0.0 1.2 -1.2 -1.1 1.2 0.1
Medication: Aspirin 0.4 0.6 4.5 0.5 -0.6 -0.0 0.4 -0.1 -0.8 2.1 0.1 -1.2 -0.6 0.6 1.1 -0.7 -0.8 -0.6 -0.3 -0.3 -0.5 -0.8 -0.9 -0.7 -0.7 -0.6 -0.5 -0.7 -0.7 -1.2 -0.6 0.1 -0.6 -0.9 -0.1
Supplements: Vitamin C 0.5 0.6 2.5 -1.6 0.3 1.1 0.7 -1.0 -0.2 1.6 1.4 -0.6 0.5 1.0 -0.4 0.1 -0.1 -0.3 1.3 0.3 -0.8 -0.2 -0.2 -0.2 0.4 0.2 -0.4 1.1 0.0 0.5 0.8 -1.2 -0.6 -0.0 -0.3
Knee pain experienced in last month 0.4 0.6 3.5 -0.1 0.2 0.3 0.8 -0.3 0.5 1.1 0.3 0.5 0.8 0.8 -0.1 -0.3 -0.2 0.3 1.1 0.4 1.9 0.8 0.4 1.3 0.6 0.6 0.8 0.6 1.4 0.9 0.5 -0.8 1.2 0.6 1.1
Hypertension (Self-reported) 0.6 1.7 11.4 0.2 2.2 0.9 1.3 0.4 -1.1 0.4 -0.1 -0.6 -0.5 -0.0 3.4 2.0 1.4 -0.2 -2.4 -1.5 -1.7 -0.9 -1.3 -0.9 0.1 -1.0 0.2 -0.4 -0.9 -0.6 0.1 -0.3 -3.0 -1.0 -0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 5.6 0.0 -0.5 -0.4 0.4 -0.3 0.7 -0.9 -0.5 0.6 1.3 0.0 1.5 -1.0 0.1 1.0 -0.6 0.8 1.4 1.5 1.0 1.3 1.1 0.8 -0.3 0.6 2.4 2.3 0.5 0.3 1.3 1.0 0.7
Illnesses of father: Heart disease 1.5 2.1 5.4 1.2 0.3 0.3 -0.4 1.4 -2.0 1.9 -0.5 -1.6 -1.5 -0.8 -1.0 1.0 0.3 -0.6 -1.2 -1.2 -2.0 -2.1 -2.3 -1.8 -1.6 -1.9 -1.1 -1.6 -1.8 -1.6 -1.5 1.4 -1.7 -2.1 -1.6
Illnesses of siblings: Diabetes 0.6 0.7 4.5 1.0 1.0 0.3 -0.3 1.2 -0.7 2.1 -0.5 -0.7 -0.5 -0.4 -1.5 0.4 0.1 -0.2 0.5 -2.0 0.1 -0.5 -0.8 -0.1 -1.0 -0.6 0.3 -0.5 -0.7 -0.7 -0.6 0.1 1.2 -0.7 0.2
Smoking status: Previous 2.3 3.4 12.9 -1.8 0.8 1.4 0.4 -1.8 2.7 -2.2 1.8 1.5 2.4 1.2 0.8 1.2 0.2 0.3 3.6 1.9 1.7 2.0 2.3 2.0 1.7 2.6 2.5 2.1 1.7 1.3 2.1 -1.3 0.6 2.5 1.6
Forced expiratory volume in 1-second (FEV1), predicted 2.6 5.5 22.2 -2.1 2.3 3.4 2.1 -2.4 2.1 0.2 2.9 3.1 2.6 2.8 -2.4 2.4 1.1 1.6 4.7 1.9 1.4 1.8 1.8 2.0 2.7 2.3 2.3 2.6 1.9 1.3 2.8 -2.4 0.3 2.1 2.3
Whole body fat-free mass 0.6 3.5 13.2 -2.4 1.7 1.2 1.3 -2.5 1.8 -0.1 2.5 1.5 1.8 2.3 -2.9 0.7 0.2 2.3 3.6 -0.1 1.4 1.6 1.8 2.0 1.6 2.1 1.9 1.6 1.4 1.0 2.0 -3.0 -0.4 1.8 1.9
Leg fat-free mass (right) 0.7 3.7 8.2 -2.2 1.7 1.2 1.8 -2.5 1.8 -0.7 2.5 2.4 1.8 2.2 -1.9 0.9 0.5 2.4 2.9 1.0 1.7 1.7 1.9 2.2 1.9 2.1 2.2 1.8 1.6 1.2 2.1 -2.9 -0.5 1.9 2.3
Arm fat percentage (left) 0.2 0.9 3.0 -1.7 -1.2 -1.1 0.7 -0.9 0.7 -1.1 0.3 -0.3 0.4 0.5 0.5 -1.2 -0.0 1.4 -0.4 0.1 0.5 1.0 1.0 1.1 1.0 0.8 -0.3 0.4 1.3 1.5 0.6 -1.5 0.6 0.8 1.3
Average weekly red wine intake 1.2 1.7 5.4 1.8 0.4 -0.6 -1.5 1.1 -1.4 1.2 -0.8 -1.6 -1.4 -0.8 -0.5 0.1 -0.9 -1.5 0.6 -2.0 -0.7 -1.5 -1.4 -1.3 -1.8 -1.4 -0.1 -1.6 -1.9 -2.3 -1.5 1.3 -0.9 -1.5 -0.7
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.3 -0.0 -0.9 0.5 0.7 -0.6 0.1 0.7 0.9 0.2 0.5 1.0 -1.1 -0.2 0.3 -0.3 0.5 -0.1 -0.9 -0.2 -0.1 -0.4 0.9 0.3 -0.4 0.9 0.2 -0.1 0.6 -0.3 0.9 0.1 0.4
Mood swings 0.4 0.7 4.1 -1.8 -0.6 0.2 -0.1 -0.2 0.4 -0.6 0.7 0.8 0.6 0.1 -2.0 0.2 1.1 -0.7 0.9 0.1 0.4 0.7 0.5 0.7 0.8 0.4 -0.4 0.5 1.5 1.6 0.5 -0.6 -1.1 0.5 1.2
Loneliness, isolation 1.5 2.0 6.2 -1.3 -0.4 0.4 0.2 -1.1 1.5 -1.0 1.3 -0.7 1.8 0.9 -0.7 0.2 0.5 -0.0 1.2 0.3 1.9 1.9 1.6 1.8 2.0 1.6 1.0 1.9 2.4 2.5 1.6 -1.6 -0.1 1.7 2.2
Long-standing illness, disability or infirmity 0.3 0.4 1.8 0.7 -0.6 0.5 -0.1 0.3 -0.8 0.9 -0.9 0.4 -0.1 -0.2 1.1 -0.8 -0.8 -0.5 -1.4 -0.0 -0.7 -0.2 -0.6 -0.3 -0.1 -0.6 -0.9 -0.9 0.4 -0.2 -0.6 0.7 -0.3 -0.5 0.2
Ever had bowel cancer screening 0.4 0.4 2.4 -1.1 1.2 0.5 0.2 0.1 0.1 -0.6 0.7 0.4 0.0 -0.2 1.4 1.2 1.1 -0.5 -1.0 0.3 -0.8 -0.0 0.2 -0.3 0.0 0.2 0.2 0.5 -0.5 -0.3 0.3 -0.5 -1.6 0.1 0.1
Diabetes diagnosed by doctor 0.4 0.7 1.8 0.8 -1.0 -0.9 -0.9 0.3 -0.6 0.2 -0.8 -0.9 -1.0 -0.4 0.3 -1.3 -1.1 0.7 -0.7 -1.3 -0.9 -0.8 -0.6 -0.4 -0.5 -0.7 -0.9 -1.1 -0.2 -0.7 -1.0 0.8 -1.4 -0.7 0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 5.6 -0.8 1.7 1.5 1.3 -0.7 0.1 -0.0 0.8 0.2 0.1 0.8 2.4 1.6 0.9 -0.0 0.1 0.1 -0.1 0.4 0.1 0.4 0.3 0.2 0.7 0.2 0.2 0.4 0.7 -0.5 -0.9 0.2 -0.2
Friendships satisfaction 3.0 3.7 11.1 0.6 -3.3 -2.7 -3.0 1.9 -1.7 -0.6 -2.0 -2.9 -2.3 -2.2 -1.4 -2.4 -1.6 -1.2 -0.9 -1.7 -1.6 -1.6 -1.2 -1.8 -2.0 -1.8 -3.0 -2.1 -1.3 -0.6 -2.3 1.8 -0.1 -1.6 -1.8
Qualifications: nursing, teaching 0.5 0.8 5.9 0.9 -0.4 -0.3 -1.4 0.8 -0.4 1.7 -0.5 -0.6 -0.5 -0.2 -2.4 -0.6 -1.7 -1.0 0.9 -0.6 0.1 -0.7 -0.8 -0.7 -1.1 -0.6 -0.1 -0.5 -0.7 -1.1 -0.8 0.7 0.3 -0.7 -0.8
Commuting to job workplace: Walk 0.2 0.2 2.6 -0.6 -0.6 0.1 -0.4 -0.0 -0.2 0.1 0.4 -1.6 -0.2 0.4 -0.1 0.3 -0.3 -1.1 0.3 -0.3 -0.6 -0.0 0.0 -0.5 0.4 -0.0 -0.6 0.1 -0.4 -0.1 0.3 -0.6 -0.7 -0.1 0.0
Eye problems/disorders: Cataract 0.3 0.3 1.2 0.2 -0.7 0.3 -0.7 0.9 -0.7 -0.5 -0.8 -0.6 -0.4 -0.6 -0.7 0.3 -0.4 -0.3 -1.0 -0.1 -0.6 -0.7 -0.7 -0.7 -0.3 -0.6 -0.5 -0.4 -0.3 -0.2 -0.4 0.6 -0.5 -0.6 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 7.3 0.1 -0.4 -0.6 -1.2 1.6 -0.6 0.3 -0.5 -0.3 -0.9 -0.6 1.5 -0.0 -1.1 -1.1 -0.6 -0.6 -1.1 -0.5 -0.7 -0.8 -0.4 -0.8 -1.3 -0.9 0.0 -0.6 -1.0 1.1 -2.7 -0.8 0.9
Medication for cholesterol 0.8 1.2 9.3 -0.9 -1.0 -0.8 -0.9 -0.5 1.0 -1.2 -0.1 1.1 0.7 0.3 -3.1 -1.4 -1.6 1.8 0.7 0.2 1.0 0.9 1.0 1.0 0.8 0.8 -0.0 0.7 1.3 1.3 0.6 -0.5 1.1 0.9 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 3.8 0.5 -1.2 -1.4 -0.8 1.0 0.0 -0.1 -0.8 -0.6 -0.3 -0.9 0.1 -1.3 -0.3 -2.0 -0.7 -1.0 -0.0 -0.2 -0.2 -0.2 -0.6 -0.2 -1.0 -0.2 0.1 0.3 -0.7 0.3 0.3 -0.2 -0.3
Back pain experienced in last month 3.0 4.4 8.6 -1.8 2.9 2.5 2.5 -1.6 1.7 0.6 2.4 1.3 2.5 1.6 1.6 2.3 2.9 0.2 2.2 2.6 2.0 2.3 2.0 1.9 2.2 2.0 2.5 2.6 1.9 2.2 2.5 -2.2 1.2 2.1 1.4
Mineral and other dietary supplements 0.4 0.5 3.6 0.2 0.4 0.9 0.8 0.3 -0.5 -0.1 -0.3 -0.4 -0.4 -0.4 -0.0 1.3 1.9 -0.2 -1.5 1.4 -0.5 -0.4 -0.5 -0.7 0.1 -0.7 -0.2 0.0 -0.6 -0.2 -0.1 0.5 1.3 -0.5 -0.2
Breast cancer (self-reported) 2.0 2.4 7.8 1.7 -1.1 -0.7 -0.8 1.4 -1.8 0.4 -1.8 -2.0 -1.8 -1.3 0.2 -0.6 0.3 -0.9 -2.8 -1.1 -2.0 -1.8 -1.9 -2.2 -1.2 -2.1 -1.9 -1.6 -1.7 -1.5 -1.6 1.6 -0.8 -2.0 -1.4
Asthma (self-reported) 0.9 1.8 10.8 0.3 0.9 2.1 2.0 -0.8 -1.7 3.3 0.2 0.6 -1.0 1.7 1.1 0.6 -0.3 0.5 -0.5 -1.2 -1.1 -1.4 -2.1 -0.8 -1.0 -1.2 -0.0 -1.4 -1.8 -2.0 -0.3 -1.0 0.0 -1.7 -1.9
Osteoporosis (self-reported) 0.3 0.3 1.4 -0.8 0.8 0.5 -0.2 -0.6 0.9 -0.5 0.4 -0.4 0.6 0.4 0.3 0.7 0.4 0.4 1.2 -0.0 -0.3 0.4 0.5 0.3 0.5 0.7 0.9 0.6 -0.2 0.0 0.8 -0.8 0.5 0.6 -0.2
Osteoarthritis (self-reported) 0.7 0.9 3.6 -0.1 -1.0 -1.6 -1.0 0.3 0.4 0.0 -0.8 -0.1 0.3 0.2 -1.8 -1.9 -1.8 0.7 0.5 -1.3 1.3 0.9 0.6 1.2 0.1 0.4 0.1 -0.7 1.3 0.4 -0.3 -0.1 0.9 0.5 1.2
Medication: Aspirin 0.2 0.3 1.8 0.3 -0.4 -0.1 0.5 -0.4 -0.4 1.4 0.3 -1.0 -0.3 0.8 1.0 -0.6 -0.9 -0.3 0.0 -0.0 -0.1 -0.5 -0.6 -0.2 -0.4 -0.3 0.0 -0.4 -0.4 -0.9 -0.2 -0.2 -0.4 -0.5 -0.1
Medication: Gliclazide 0.4 0.4 3.0 -0.3 -1.5 -0.2 0.9 -0.9 -0.2 1.2 0.2 0.4 -0.2 1.0 -0.1 -1.7 -0.1 -0.7 -1.1 -0.1 -0.4 -0.3 -0.4 -0.1 -0.1 -0.0 -0.7 -0.4 -0.2 -0.7 -0.3 -0.2 0.7 -0.3 0.5
Illnesses of father: None of the above (group 1) 2.9 3.5 9.0 -1.3 0.5 0.8 1.0 -1.6 2.1 -1.8 1.5 2.4 1.8 1.1 -0.3 0.7 0.6 2.6 1.5 3.0 2.6 2.4 2.5 2.2 2.0 2.0 2.1 2.1 1.9 1.8 1.9 -1.5 2.1 2.2 2.3
Smoking status: Current 0.1 0.2 2.8 -0.5 -0.4 0.7 0.8 -0.2 -0.5 1.7 -0.1 -0.8 -0.1 0.3 0.2 -0.1 0.5 -0.1 0.3 -0.2 -0.4 0.0 -0.2 -0.2 0.1 -0.2 -0.4 -0.1 -0.2 0.0 0.1 -0.6 0.7 -0.2 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 7.0 -2.6 -0.9 0.3 1.4 -2.0 1.5 -0.7 2.0 1.9 1.0 1.6 -1.9 -0.5 0.1 0.6 1.2 1.2 0.8 1.1 1.4 1.1 1.5 1.5 0.3 1.8 0.8 1.3 1.6 -2.6 1.3 1.2 0.8
Whole body water mass 0.6 3.6 13.4 -2.5 1.6 1.2 1.4 -2.5 1.8 0.0 2.6 1.4 1.8 2.4 -3.0 0.7 0.2 2.3 3.7 -0.1 1.4 1.6 1.8 2.0 1.7 2.1 1.9 1.7 1.3 0.9 2.1 -3.1 -0.5 1.8 1.9
Leg predicted mass (right) 0.7 3.7 8.5 -2.2 1.7 1.2 1.8 -2.6 1.8 -0.6 2.5 2.3 1.8 2.3 -2.0 0.9 0.4 2.4 2.9 0.9 1.7 1.7 1.8 2.2 1.9 2.1 2.2 1.7 1.6 1.1 2.1 -2.9 -0.5 1.9 2.2
Arm fat mass (left) 0.3 1.3 4.5 -2.1 -0.7 -0.6 0.9 -1.3 1.2 -1.0 1.0 -0.1 0.9 1.2 -0.5 -0.9 -0.2 1.9 0.8 -0.2 0.7 1.2 1.4 1.4 1.3 1.3 0.2 0.7 1.5 1.3 1.0 -2.1 0.3 1.2 1.7
Number of self-reported non-cancer illnesses 0.5 0.8 5.3 -0.7 0.3 1.1 1.8 -0.9 -0.6 1.5 0.5 -0.4 -0.0 1.8 2.3 0.3 0.5 0.2 -0.1 -0.8 -1.5 -0.2 -0.5 -0.4 0.6 -0.2 -0.0 -0.4 -0.6 -1.0 0.6 -1.2 -0.5 -0.3 -0.3
Average weekly champagne plus white wine intake 0.6 0.9 5.4 -0.5 1.9 1.7 1.0 -0.9 -0.6 2.3 1.5 1.0 -0.0 1.3 0.3 1.5 0.2 -0.2 0.5 0.2 -0.2 -0.6 -0.9 -0.1 -0.7 -0.2 0.8 -0.1 -0.8 -1.0 0.2 -0.7 0.5 -0.6 -1.0
Miserableness 0.6 1.0 5.7 -2.1 -0.4 0.9 -0.1 -0.3 0.4 0.8 1.2 -0.1 0.8 -0.0 -0.0 0.6 0.7 -0.2 0.4 1.4 0.9 1.0 0.5 1.1 0.8 0.5 -0.6 0.9 2.0 2.4 0.4 -0.6 -0.3 0.5 1.9
Guilty feelings 1.8 2.8 7.2 -2.1 1.5 2.7 1.2 -0.9 1.5 0.1 2.4 -0.0 2.3 1.4 -0.3 2.3 2.2 0.1 2.0 1.1 0.7 1.4 1.5 1.2 2.3 1.7 1.4 2.5 1.8 1.7 2.2 -1.4 0.3 1.7 1.9
Wears glasses or contact lenses 0.7 0.9 6.2 1.0 -0.0 -1.0 -1.2 1.0 -0.8 -0.3 -1.3 -0.4 -0.7 -1.5 2.5 0.2 -0.1 -1.2 -0.8 -1.0 -0.7 -0.8 -0.9 -0.8 -0.8 -0.9 -0.7 -0.7 -0.5 -0.1 -1.0 1.0 0.2 -0.8 -0.5
Ever taken oral contraceptive pill 1.5 1.7 8.4 -1.1 1.1 1.5 0.7 -1.5 0.9 -1.4 1.7 2.8 1.1 1.3 -0.7 1.1 -0.5 1.7 2.9 1.4 0.5 0.6 0.9 0.9 1.1 1.2 1.3 1.3 0.5 0.8 1.5 -1.7 -0.1 1.0 -0.2
Hearing aid user 0.6 0.7 3.3 0.5 -0.2 -0.5 -0.5 0.2 -0.7 0.9 -0.7 -0.1 -0.8 -0.7 1.2 -0.6 -0.7 -0.7 -1.8 -1.0 -1.1 -0.9 -0.8 -0.7 -1.0 -0.7 -0.7 -1.1 -0.7 -0.9 -1.0 0.3 -0.7 -0.8 -0.2
Mother’s age at death 2.3 2.9 6.4 1.9 1.2 -0.0 -0.9 2.5 -2.2 0.5 -1.3 -1.1 -1.8 -1.0 0.0 1.0 -0.1 -1.5 -0.9 -1.4 -2.1 -2.4 -2.5 -2.5 -1.5 -2.2 -0.7 -1.3 -2.4 -2.5 -1.4 2.1 -1.8 -2.2 -1.8
Financial situation satisfaction 0.3 0.3 2.9 -0.1 -1.4 0.2 -0.0 0.3 0.1 0.6 0.1 -1.7 0.1 0.2 1.0 -0.6 -0.3 -1.4 -0.1 0.9 0.4 -0.1 0.1 0.0 0.1 0.0 -0.0 -0.1 0.4 -0.0 -0.0 0.1 0.3 0.1 0.3
Tinnitus: Yes, now most or all of the time 2.5 3.0 10.4 2.0 3.2 2.0 1.3 1.3 -2.1 2.6 0.2 -0.6 -1.2 -0.8 1.0 2.8 2.6 -0.8 -2.5 -0.1 -1.9 -1.8 -2.0 -2.3 -1.2 -1.8 -0.6 -0.2 -2.0 -1.4 -0.8 1.8 0.2 -1.8 -1.7
Commuting to job workplace: Public transport 1.3 1.6 5.7 1.1 -2.2 -1.5 -1.6 0.7 -1.1 0.7 -1.3 -1.0 -1.3 -1.0 0.6 -1.6 -1.0 -0.8 -1.4 -1.7 -1.2 -1.1 -1.1 -1.5 -0.9 -1.3 -2.4 -1.2 -1.0 -0.5 -1.4 0.9 0.8 -1.3 -0.8
Eye problems/disorders: Glaucoma 1.4 1.7 5.0 2.2 -0.6 -1.1 -1.2 1.9 -1.3 0.2 -1.9 -0.6 -1.1 -1.1 -0.3 -1.4 -1.6 -0.8 -1.4 -0.9 -0.7 -1.7 -1.4 -1.4 -1.2 -1.4 -0.5 -1.4 -1.4 -2.2 -1.5 1.6 0.7 -1.3 -0.4
Medication: Blood pressure 0.9 1.6 3.6 1.1 1.5 0.8 1.2 0.5 -1.5 1.5 -0.2 -0.9 -0.9 -0.0 1.9 1.6 1.6 -1.3 -1.3 -1.4 -1.6 -1.5 -1.7 -1.4 -0.9 -1.4 0.1 -0.8 -1.6 -1.6 -0.5 0.4 -1.8 -1.5 -1.5
Pain type(s) experienced in last month: Hip pain 1.9 2.4 5.4 -2.3 -0.1 0.8 1.7 -1.9 1.9 -0.5 1.7 0.4 1.7 1.9 -0.1 0.2 0.5 0.4 1.8 1.7 1.9 2.0 1.8 2.0 1.6 2.0 1.7 1.4 1.6 1.2 1.8 -2.2 0.9 1.8 1.5
Supplements: Fish oil (including cod liver oil) 0.9 1.2 9.4 0.3 -1.2 -2.1 -2.2 0.3 0.4 -0.4 -0.8 -0.5 -0.3 -0.6 -2.0 -2.0 -3.1 0.3 1.1 -1.8 0.8 0.6 0.6 0.7 -0.8 0.4 -0.2 -0.6 0.5 0.3 -0.6 0.3 -0.2 0.4 -0.1
High cholesterol (Self-reported) 0.1 0.2 3.0 0.2 -0.2 -0.2 0.0 0.5 0.0 -0.2 0.1 -0.2 -0.0 0.0 1.7 -0.2 -0.0 -0.2 -0.2 0.5 -0.2 0.2 0.2 -0.3 0.3 0.1 -0.3 0.0 0.2 -0.1 -0.1 0.6 -0.3 0.1 0.6
Medication: Bendroflumethiazide 0.6 0.9 9.4 -0.3 0.5 0.1 1.1 -0.3 -1.0 0.4 -0.3 -0.1 -0.7 0.1 3.1 0.2 0.1 -0.9 -2.3 -1.3 -1.3 -0.7 -0.8 -0.6 -0.3 -0.8 -0.5 -0.6 -0.8 -0.4 -0.2 -0.5 -0.8 -0.8 -1.0
Medication: Paracetamol 0.6 0.9 3.5 -1.9 -0.6 1.2 1.7 -0.8 0.3 1.6 0.6 -0.3 0.9 1.6 0.5 -0.1 0.8 -0.0 -0.7 0.7 0.5 0.9 0.1 0.9 0.9 0.5 -0.1 0.4 1.4 1.1 0.9 -1.4 0.3 0.4 0.5
Medication: Lisinopril 0.3 0.4 2.4 -0.7 0.0 1.4 0.9 -0.5 -0.6 0.4 0.0 1.2 0.0 0.8 -0.9 0.2 0.4 -0.4 -0.6 -0.6 -1.5 -0.5 -0.5 -0.6 0.7 -0.4 -0.5 -0.3 -0.2 -0.5 0.4 -0.6 -0.3 -0.3 -0.1
Medication: Atorvastatin 0.1 0.1 0.5 -0.1 -0.1 0.1 0.3 -0.7 -0.1 0.1 -0.1 -0.3 -0.0 0.5 0.7 0.3 -0.2 -0.2 -0.5 -0.0 0.2 0.2 -0.5 0.1 0.0 -0.1 0.1 -0.4 0.0 -0.2 0.0 -0.2 0.2 -0.2 0.2
Illnesses of father: High blood pressure 2.3 2.8 10.0 0.5 -0.7 -1.3 -1.0 1.5 -1.8 1.2 -1.7 -1.5 -2.1 -1.5 0.7 -0.8 -0.4 -2.2 -0.8 -3.2 -2.2 -1.7 -1.8 -1.5 -2.2 -1.9 -2.2 -2.6 -1.6 -1.2 -2.1 1.0 -1.5 -1.9 -1.5
Alcohol drinker status: Never 5.0 5.9 12.9 1.7 -2.5 -3.2 -2.3 2.5 -2.7 0.8 -2.5 -0.3 -2.9 -2.3 -0.2 -2.7 -2.3 -1.9 -3.6 -2.4 -1.9 -2.7 -2.6 -2.4 -3.1 -2.7 -3.2 -3.3 -2.2 -2.2 -3.3 1.9 -0.7 -2.8 -1.7
Ever smoked 1.0 1.7 9.4 -1.4 -0.3 1.2 0.8 -1.4 1.6 -0.9 1.0 0.3 1.8 1.2 0.1 0.0 0.5 -0.6 3.1 1.5 1.2 1.4 1.7 1.2 1.4 1.8 1.3 1.5 1.1 0.8 1.5 -1.1 0.8 1.8 0.9
Basal metabolic rate 0.6 3.5 11.7 -2.6 1.3 0.9 1.4 -2.5 1.8 -0.1 2.5 1.3 1.7 2.3 -2.7 0.4 0.1 2.4 3.4 -0.1 1.4 1.7 1.8 2.1 1.7 2.1 1.7 1.6 1.5 1.2 2.0 -3.1 -0.3 1.8 2.0
Leg fat percentage (left) 0.5 1.6 4.0 -1.8 -1.1 -0.5 0.9 -1.1 1.4 -0.7 0.7 -1.1 1.4 1.1 0.5 -1.1 0.1 1.2 1.2 0.1 1.3 1.6 1.6 1.8 1.5 1.6 0.5 0.9 2.0 1.7 1.1 -1.7 1.1 1.6 1.9
Arm fat-free mass (left) 0.6 3.0 11.9 -2.3 1.1 0.7 1.1 -2.2 1.6 0.2 2.2 0.8 1.6 2.4 -3.0 -0.1 -0.4 2.3 3.5 -0.6 1.5 1.5 1.6 1.9 1.3 1.9 1.6 1.2 1.4 0.7 1.7 -2.9 -0.0 1.7 1.8
Number of operations (self-reported) 0.2 0.3 1.2 -1.1 0.5 0.6 -0.3 -0.3 0.6 0.2 0.2 -0.4 0.4 -0.0 0.9 0.7 0.3 -1.1 1.1 0.0 0.1 0.8 0.4 0.7 0.0 0.5 0.0 0.3 0.7 1.0 0.3 -0.2 0.5 0.5 0.1
Average weekly beer plus cider intake 0.6 0.8 4.6 -0.3 0.3 0.2 0.2 0.7 0.9 -1.2 0.6 -1.3 0.9 -1.0 0.2 1.1 2.1 -1.9 -0.8 1.0 0.3 0.6 1.0 0.3 0.6 0.8 0.2 1.4 0.8 1.6 0.5 0.0 -0.4 1.0 0.7
Irritability 1.0 1.8 5.1 -2.2 0.1 1.1 -0.4 -0.6 1.5 -1.4 1.2 0.3 1.6 0.1 -0.3 0.7 1.2 0.2 1.7 1.6 0.7 1.4 1.6 1.4 1.7 1.6 0.4 1.6 2.3 2.2 1.2 -0.6 -1.0 1.6 2.0
Risk taking 0.6 0.8 3.0 -1.2 0.5 0.8 0.8 -0.6 1.0 -0.2 0.7 0.6 1.4 0.9 -0.3 0.5 0.5 0.3 1.3 1.1 1.4 0.9 0.9 1.5 0.6 0.9 1.7 0.4 1.0 0.3 0.8 -0.8 0.7 1.0 0.7
Ever had prostate specific antigen (PSA) test 1.6 1.8 5.8 -0.3 -1.9 -1.4 -0.7 0.3 -1.5 1.1 -0.5 0.5 -1.6 -0.4 -1.2 -1.8 -0.7 -0.7 -1.8 -2.3 -2.0 -1.5 -1.3 -1.2 -1.3 -1.2 -2.4 -1.6 -0.9 -0.9 -1.4 0.1 -2.1 -1.4 -0.8
Fractured/broken bones in last 5 years 1.7 2.2 8.3 -1.2 2.7 2.6 1.8 -0.5 0.7 1.3 1.6 1.0 1.5 0.9 1.3 2.9 2.7 0.1 1.8 2.1 1.0 1.0 0.6 0.9 1.1 0.9 1.8 1.6 0.7 1.0 1.5 -1.2 0.5 0.9 0.9
Age started oral contraceptive pill 1.5 1.9 5.0 2.1 -0.8 -1.6 -1.8 1.3 -1.1 -0.3 -1.5 -2.0 -1.7 -1.0 -0.5 -0.9 -1.5 -1.2 -0.9 -1.6 -0.9 -1.7 -1.4 -1.6 -1.2 -1.4 -0.7 -1.5 -1.8 -2.2 -1.4 1.2 -0.0 -1.4 -0.4
Diastolic blood pressure, automated reading 1.2 3.7 10.7 -3.3 1.5 0.9 2.1 -2.3 2.2 -0.9 1.7 0.8 1.9 2.4 1.4 0.7 0.2 1.0 0.5 -0.3 2.0 2.5 2.0 3.0 2.0 2.4 2.1 1.7 2.3 2.2 2.3 -3.0 0.2 2.1 1.8
Ever depressed for a whole week 0.5 0.6 2.8 -1.7 0.1 1.2 1.4 -1.1 0.4 0.9 1.6 -0.1 0.5 1.2 -0.3 0.3 0.4 0.1 0.7 0.6 -0.8 0.1 0.5 0.0 0.8 0.6 -0.1 0.6 -0.2 0.1 0.9 -1.5 -0.8 0.4 0.2
Unable to work because of sickness or disability 1.4 1.9 4.9 -1.3 1.9 1.9 1.0 -0.8 1.2 -0.7 1.1 2.2 1.9 0.6 2.2 1.5 0.6 1.2 1.3 1.8 0.8 1.1 1.2 1.2 1.6 1.3 1.3 1.6 1.4 1.4 1.5 -0.8 -0.3 1.4 1.3
Commuting to job workplace: Cycle 0.6 0.7 3.1 1.1 -0.5 -0.4 -1.5 0.5 -0.6 -0.2 -0.7 -1.8 -0.8 -0.9 -0.3 -0.3 -0.8 -0.7 -0.2 -0.2 -0.4 -0.9 -0.9 -1.1 -1.0 -0.9 -0.8 -1.0 -1.1 -1.0 -1.0 0.9 -0.4 -0.9 -0.8
Myopia 0.3 0.4 4.1 -0.4 -0.2 0.5 0.0 -0.3 0.1 -0.7 0.0 2.0 0.4 0.4 -1.0 -0.0 -1.0 0.6 1.2 0.4 -0.3 0.5 0.6 0.2 1.0 0.3 -0.4 0.4 0.8 0.7 0.5 0.1 -0.4 0.5 0.8
Vascular/heart problems diagnosed by doctor 0.5 1.4 13.8 0.1 -2.2 -1.3 -1.7 -0.0 0.7 -0.4 -0.3 -0.3 -0.0 -0.4 -3.7 -1.8 -1.5 0.3 1.8 0.9 1.2 0.6 1.0 0.6 -0.5 0.4 -0.3 0.0 0.4 0.3 -0.4 0.6 2.8 0.6 0.1
Cholesterol lowering medication 0.2 0.3 3.1 0.5 -0.6 0.4 0.2 0.3 -0.4 0.9 0.1 -1.8 -0.2 0.4 0.4 -0.1 -0.4 -0.9 0.0 0.0 -0.4 -0.6 -0.7 -0.6 0.2 -0.3 -0.2 0.0 -0.3 -0.8 -0.1 0.3 0.4 -0.5 0.6
Medication: Omeprazole (e.g. Zanprol) 0.1 0.2 1.0 -0.7 -0.5 -0.2 0.1 -0.7 -0.1 0.2 0.0 0.4 0.0 0.8 -0.8 -0.5 -0.4 1.0 0.1 -0.3 -0.1 0.1 0.0 0.2 0.2 0.0 -0.4 -0.4 0.4 0.2 0.1 -0.4 0.6 0.0 -0.3
Pain experienced in last month 0.8 1.4 3.6 0.9 -0.9 -0.8 -1.7 0.1 -1.0 0.2 -0.9 0.2 -1.1 -0.5 -1.2 -0.9 -1.9 -0.0 -0.8 -1.8 -1.5 -1.6 -1.4 -1.2 -1.4 -1.1 -1.0 -1.5 -1.6 -1.6 -1.2 0.5 0.6 -1.3 -1.8
Supplements: Calcium 1.7 1.9 6.9 -2.6 1.1 2.0 1.9 -1.5 1.3 0.2 2.2 0.7 1.5 2.1 0.8 1.2 0.2 -0.7 2.1 0.5 -0.2 0.6 0.8 1.0 1.4 1.5 1.5 1.5 0.5 0.1 1.9 -1.8 -0.6 1.2 0.5
Basal cell carcinoma (self-reported) 0.7 0.8 3.7 1.3 -1.3 -1.9 -1.3 0.9 0.5 -1.3 -1.4 -1.8 -0.1 -1.0 -0.5 -1.1 -1.1 -0.1 -0.0 -0.5 1.0 0.4 0.6 0.1 -0.0 0.2 0.5 0.3 0.1 -0.1 -0.3 1.4 0.7 0.5 0.1
Heart attack/myocardial infarction (self-reported) 0.5 0.6 2.8 -0.1 -0.4 1.2 1.0 -0.5 -0.9 1.7 0.6 0.4 -0.3 1.0 -0.1 0.2 0.7 -1.1 -0.5 0.5 -1.1 -0.8 -1.0 -0.9 -0.1 -0.6 -0.5 -0.3 -0.7 -1.1 -0.1 -0.4 -1.1 -0.8 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 5.0 -0.6 -0.5 1.1 1.7 -1.3 1.2 -0.9 1.0 1.7 1.5 1.4 0.0 0.5 0.8 1.3 0.6 2.2 1.3 1.2 1.5 1.3 1.7 1.4 1.4 1.4 1.4 0.5 1.4 -0.6 -0.5 1.5 1.8
Heart disease (siblings) 0.4 0.5 3.7 0.4 -0.1 0.9 1.2 0.1 -0.5 1.4 -0.1 -1.9 -0.0 1.2 -0.5 -0.0 -0.3 0.4 -1.3 -0.4 0.0 -0.4 -0.9 -0.2 0.1 -0.3 0.2 -0.4 -0.3 -0.9 0.2 -0.2 -0.2 -0.6 -0.3
Alcohol drinker status: Previous 0.5 0.5 2.0 -0.8 0.7 1.3 0.7 0.2 0.2 0.9 0.6 -0.5 1.2 0.3 -1.0 0.7 0.9 -0.0 0.9 0.9 0.4 0.6 0.2 0.4 0.8 0.5 -0.1 1.0 1.2 1.4 0.6 -0.1 0.4 0.5 0.5
Pack years of smoking 0.5 0.8 3.5 0.3 -0.3 0.2 0.9 0.1 1.2 -1.2 0.0 -0.2 1.1 -0.1 1.9 0.4 1.1 0.1 -0.4 0.9 0.2 0.9 1.2 0.5 1.2 1.0 0.9 1.0 1.0 0.3 0.7 0.8 -1.2 1.2 1.4
Impedance of whole body 0.2 0.9 6.0 0.7 1.2 1.8 -0.1 0.6 0.0 0.6 0.2 -0.1 0.4 -0.6 2.4 2.4 1.2 -0.8 0.6 1.7 0.4 0.5 0.1 0.3 0.2 -0.0 0.9 0.6 0.3 0.9 0.3 0.7 1.6 0.2 -0.2
Leg fat mass (left) 0.5 1.8 4.8 -2.0 -0.6 -0.4 1.0 -1.4 1.5 -0.9 1.2 -0.5 1.3 1.4 -0.4 -1.0 -0.2 1.9 1.7 -0.0 1.2 1.6 1.7 1.8 1.5 1.7 0.8 1.0 1.8 1.3 1.3 -2.0 0.7 1.6 2.2
Arm predicted mass (left) 0.6 3.0 11.3 -2.4 1.2 0.9 1.3 -2.2 1.6 0.2 2.4 0.9 1.6 2.4 -2.9 0.1 -0.1 2.2 3.4 -0.5 1.3 1.4 1.6 1.8 1.4 1.9 1.5 1.2 1.3 0.6 1.7 -2.9 -0.5 1.6 1.8