Hub : Genes

ANO10

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1450 0.0360 2.6e-13 0.112 0.120 0.087 0.120 0.102 1.7e-13 1.9e-14 1.1e-10 2.1e-14 1.9e-12
2 GTEx Nerve Tibial 0.0769 0.0341 3.1e-03 0.043 NA 0.046 NA 0.039 5.3e-04 NA 3.4e-04 NA 9.4e-04
3 GTEx Skin Not Sun Exposed Suprapubic 0.1520 0.0580 2.9e-03 0.026 NA -0.005 NA -0.004 1.3e-02 NA 9.1e-01 NA 6.0e-01
4 GTEx Thyroid 0.0690 0.0320 9.8e-03 -0.003 NA -0.003 NA -0.003 7.4e-01 NA 7.8e-01 NA 8.4e-01
5 GTEx Whole Blood 0.0740 0.0260 1.7e-04 0.016 NA 0.018 NA 0.014 1.1e-02 NA 7.4e-03 NA 1.8e-02
6 METSIM Adipose 0.0288 0.0127 1.9e-03 0.022 0.015 0.016 0.012 0.016 2.7e-04 2.1e-03 1.4e-03 5.0e-03 1.8e-03
7 ROSMAP Brain Pre-frontal Cortex 0.1628 0.0456 6.1e-09 0.057 0.095 0.064 0.095 0.060 7.8e-08 3.0e-12 1.0e-08 3.1e-12 3.6e-08
8 TCGA Thyroid Carcinoma 0.1160 0.0480 1.8e-04 0.035 0.034 0.016 NA 0.029 2.3e-04 2.5e-04 1.1e-02 NA 6.8e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.3 0.4 1.3 -0.2 0.3 -0.6 0.0 0.1 0.9 0.8 -1.1
Bipolar Disorder or Schizophrenia 0.7 1.6 3.8 -1.9 -1.2 1.0 0.0 -1.7 -0.6 -0.6 -1.8
Depressed Affect (Nagel 2018) 1.0 2.0 4.1 0.6 1.1 -2.0 0.0 1.6 1.5 2.0 -1.2
Depression (Nagel 2018) 0.5 0.7 2.9 -1.0 -0.6 -1.3 0.0 -0.2 0.1 -0.2 -1.7
Intelligence (Savage-Jansen 2018) 0.4 1.1 2.7 1.4 1.6 0.7 0.0 1.1 0.6 -0.2 1.5
Neuroticism (Nagel 2018) 1.1 2.6 8.6 1.6 0.8 -2.9 0.0 1.7 1.3 1.8 -0.6
Schizophrenia (2018) 1.3 2.8 5.4 -2.3 -1.5 1.7 0.0 -2.2 -1.5 -1.4 -1.5
Schizophrenia vs Biploar Disorder 1.4 1.9 4.2 -1.7 -1.6 1.0 0.0 -1.5 -1.4 -2.0 -0.2
Worry (Nagel 2018) 1.0 2.0 4.8 2.0 0.7 -2.2 0.0 1.1 1.0 2.0 -0.7
Alzheimer’s Disease (in mother) 0.7 0.8 3.0 -0.5 -0.5 0.6 0.0 -1.0 -1.7 -0.7 0.9
Alzheimer’s Disease (in father) 1.5 1.6 3.2 -1.7 -0.4 1.2 0.0 -1.8 -1.0 -1.7 -1.1
Alzheimer’s Disease (including proxy) 1.4 2.0 4.5 -1.8 -0.9 1.0 0.0 -1.8 -2.1 -1.7 0.3
Crohns Disease (2017) 0.7 1.5 4.8 1.0 1.5 -0.4 0.0 1.3 0.7 1.4 -2.2
Irritable Bowel Disease (IBD) 1.4 3.4 6.7 2.0 2.6 -1.1 0.0 2.2 1.9 2.1 -1.4
Ulcerative Colitis (UC) 0.8 1.4 3.3 1.5 1.8 -0.3 0.0 1.1 1.4 1.6 0.0
Major Depression (MDD) 0.9 1.1 3.0 -1.1 -0.7 -1.1 0.0 -0.3 -1.7 -1.3 -1.3
Reaction Time 0.7 1.3 2.2 -0.1 1.5 1.5 0.0 -1.3 -1.2 -0.8 1.5
Verbal and Numeric Reasoning (VNR) 0.5 1.3 2.9 1.6 1.3 -0.4 0.0 1.7 1.0 0.0 1.5
Breast Cancer 0.2 0.6 1.9 0.5 -0.2 0.2 0.0 0.6 1.0 1.4 -0.9
Ovarian Cancer 0.3 0.4 1.2 -0.4 0.8 0.5 0.0 0.7 0.8 0.2 1.1
Prostate Cancer 1.0 1.4 4.9 -1.3 1.1 1.4 0.0 -0.9 -0.3 0.1 2.2
Age at First Birth 0.5 0.8 3.3 0.7 0.4 -0.9 0.0 1.8 1.0 -0.6 0.3
Bipolar Disorder (2011) 0.4 0.4 1.5 -0.5 -0.6 0.5 0.0 -0.0 -0.7 0.7 -1.2
Body Mass Index (BMI) (2010) 0.2 0.3 0.8 0.2 0.3 -0.9 0.0 0.7 0.8 -0.2 -0.3
Coronary Artery Disease (CAD) 0.7 0.8 4.9 -0.3 -1.2 0.0 0.0 -0.4 -0.2 -0.1 -2.2
Crohns Disease (2012) 1.1 1.8 5.7 0.4 1.3 -1.1 0.0 1.1 1.4 1.6 -2.4
Mean Putamen Volume 1.9 2.2 5.9 -1.5 -2.4 1.1 0.0 -1.6 0.6 -1.0 2.1
Fasting Glucose 0.9 1.1 3.6 -0.8 -1.0 -0.1 0.0 -1.9 -1.7 -0.2 -0.9
HbA1C 0.1 0.1 0.2 -0.3 -0.2 -0.0 0.0 -0.2 -0.5 0.3 0.3
HDL Cholesterol 0.5 0.9 3.3 0.9 0.9 -1.4 0.0 0.6 0.3 0.2 1.8
LDL Cholesterol 0.6 1.0 4.8 -2.2 -0.9 0.7 0.0 -1.1 -0.5 -0.7 -0.1
Lupus 0.6 0.8 2.6 1.1 0.3 -1.6 0.0 1.0 0.8 0.4 1.0
Neuroticism (2016) 1.8 2.5 11.3 1.3 0.3 -3.4 0.0 1.4 1.5 1.5 -1.0
Primary Biliary Cirrhosis 0.7 0.9 2.8 0.1 -1.2 0.7 0.0 -0.1 -1.1 -1.2 -1.7
Rheumatoid Arthritis 0.6 0.8 2.9 1.7 -0.6 -0.2 0.0 1.1 0.4 0.9 1.1
Schizophrenia (2014) 1.2 2.6 5.3 -2.1 -1.3 1.4 0.0 -2.3 -2.1 -1.3 -1.0
Triglycerides 2.2 3.7 6.6 -2.5 -1.4 2.2 0.0 -2.4 -2.0 -0.4 -2.6
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.0 -0.4 -1.3 0.2 0.0 -0.2 -0.5 -1.4 -1.3
Ulcerative Colitis 0.8 1.2 3.0 1.7 1.0 -0.7 0.0 0.6 1.5 1.6 0.3
Blood Eosinophil Count 0.5 4.1 13.3 -3.4 -0.0 0.5 0.0 -2.7 -0.9 -0.1 -3.6
Blood Platelet Count 0.0 0.3 1.5 0.2 0.2 0.2 0.0 0.2 -0.6 0.8 -1.2
Blood Red Count 0.1 1.2 4.1 1.3 1.2 -0.2 0.0 2.0 0.6 0.8 -1.1
Blood White Count 0.2 1.3 6.1 -0.2 0.7 -1.2 0.0 0.2 1.1 1.1 -2.5
Heel T-Score 0.1 0.8 2.8 0.1 0.2 -1.7 0.0 0.7 1.5 -0.0 -1.1
BMI 0.9 5.3 14.0 1.8 3.4 -3.0 0.0 3.7 1.9 0.1 0.7
Height 0.3 5.4 24.6 5.0 2.1 0.3 0.0 3.2 1.1 1.4 -0.0
Waist Hip Ratio (WHR) 1.4 6.5 42.5 -1.2 0.0 -1.9 0.0 0.5 0.4 1.9 -6.5
Systolic Blood Pressure 0.1 0.6 2.1 -0.1 -0.5 -0.4 0.0 0.2 0.6 -1.3 1.4
Smoking Status 0.3 0.8 3.1 -0.4 -1.4 1.0 0.0 -1.8 -0.1 0.6 -0.3
Allergy or Eczema 2.1 5.6 11.7 -2.9 -2.6 2.7 0.0 -3.4 -1.9 -2.2 -1.6
Cardiovascular Disease 0.1 0.4 1.1 -0.9 -0.7 -0.4 0.0 -0.1 -0.8 -1.0 -0.4
Hypothyroidism (self reported) 0.1 0.3 1.4 0.1 -0.5 0.2 0.0 0.4 0.7 0.2 1.2
Respiratory disease 0.6 1.3 4.1 -1.0 -2.0 -0.5 0.0 -1.3 -0.9 -1.3 0.9
Type 2 Diabetes (T2D) (2018) 0.1 0.1 0.5 0.0 0.4 -0.3 0.0 -0.7 0.1 -0.6 -0.1
Lung FEV1/FVC ratio 0.7 3.7 6.5 2.2 2.3 -2.3 0.0 2.5 2.5 -0.6 1.0
Lung FVC 1.7 8.5 18.8 3.7 4.3 -2.9 0.0 3.5 3.0 2.2 -1.2
Neuroticism 2.0 4.9 14.1 2.2 1.4 -3.8 0.0 2.3 1.8 3.0 -1.0
Chronotype (morning person) 0.1 0.3 1.2 0.3 -0.6 -0.5 0.0 0.1 -0.2 -0.1 -1.1
Hair Pigment 0.0 1.2 6.6 2.6 0.8 -0.3 0.0 0.3 0.4 1.2 0.5
Tanning 0.1 0.8 2.0 -1.2 -1.0 0.2 0.0 -0.9 -0.9 -1.4 -0.6
Hand grip strength (left) 1.3 3.5 7.1 2.2 2.0 -1.4 0.0 2.3 2.7 2.1 0.3
Number of treatments/medications taken 0.3 0.5 1.3 -0.6 -1.0 0.2 0.0 -0.4 -1.1 -0.6 -0.7
Average weekly spirits intake 0.4 0.5 2.1 -0.6 -0.2 -1.5 0.0 -0.2 0.1 -0.0 -1.1
Sensitivity / hurt feelings 0.2 0.3 1.7 0.3 0.1 -1.3 0.0 0.2 -0.0 0.8 0.0
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.0 -0.0 -0.2 -1.0 0.0 -0.5 -0.0 -0.2 -1.0
Hearing difficulty/problems: Yes 0.4 0.7 3.4 0.2 0.1 -1.4 0.0 0.0 -0.3 -1.9 0.2
Relative age of first facial hair 0.3 0.7 2.5 -1.6 0.6 1.1 0.0 -0.6 -0.6 0.5 -0.6
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 4.4 0.6 0.5 -2.1 0.0 1.1 0.8 -0.7 0.1
Ever used hormone-replacement therapy (HRT) 0.3 0.3 1.2 -0.9 -1.1 0.2 0.0 -0.3 0.2 -0.6 -0.5
Ever had hysterectomy (womb removed) 0.7 0.8 2.4 -0.2 -0.8 1.0 0.0 -0.9 1.1 1.5 -0.5
Systolic blood pressure, automated reading 0.4 1.3 2.6 1.3 1.1 -1.5 0.0 1.5 1.6 -0.3 0.5
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 3.5 -0.2 0.7 1.9 0.0 -0.5 -0.7 -0.0 -0.0
Angina 0.6 0.8 3.1 1.8 1.0 -0.1 0.0 -0.1 0.2 0.6 1.4
Medication for hormone replacement therapy 0.6 0.7 2.7 -1.6 -0.5 0.6 0.0 -1.2 -0.5 -0.7 0.2
Vitamin and mineral supplements 0.2 0.3 0.7 0.4 -0.9 -0.2 0.0 0.4 -0.7 -0.8 -0.1
Supplements: Zinc 0.5 0.6 1.5 0.1 1.2 -0.5 0.0 -0.3 0.9 -0.9 1.0
Medication: Co-codamol 0.3 0.3 1.7 0.0 0.2 1.3 0.0 -0.3 -0.5 0.3 0.6
Medication: Metformin 0.5 0.7 2.3 1.2 1.5 -0.7 0.0 0.8 0.5 -0.1 -0.4
Diabetes (father) 0.2 0.3 0.9 -0.5 0.3 0.4 0.0 -0.9 -0.1 -0.7 0.5
Diabetes (mother) 0.2 0.3 0.9 0.6 -0.2 0.1 0.0 -0.9 0.0 -0.9 -0.0
Severe depression (siblings) 4.8 5.4 11.1 -3.3 -1.5 2.7 0.0 -2.9 -3.0 -2.1 -0.4
Pack years adult smoking proportion 0.2 0.3 1.0 -0.0 -0.6 -1.0 0.0 -0.1 0.5 -0.8 -0.6
Impedance of leg (right) 0.2 0.9 2.0 0.8 -1.4 1.0 0.0 -1.0 0.9 1.3 0.5
Leg fat-free mass (left) 0.7 3.5 10.1 2.4 2.9 -1.4 0.0 3.2 1.4 -0.1 0.4
Trunk fat percentage 0.4 1.7 5.3 1.7 1.2 -0.0 0.0 2.0 0.3 0.2 2.3
Hand grip strength (right) 2.8 7.6 14.7 3.3 3.2 -1.4 0.0 3.1 3.8 3.4 0.7
Townsend deprivation index at recruitment 2.9 4.1 10.6 -1.7 -2.9 0.3 0.0 -2.4 -2.1 -3.3 -0.5
Current tobacco smoking 0.6 0.9 3.4 1.2 -0.6 -1.3 0.0 -0.1 1.9 0.5 0.4
Average weekly fortified wine intake 0.2 0.2 0.4 -0.6 -0.7 0.3 0.0 -0.5 0.2 -0.5 0.3
Maternal smoking around birth 0.3 0.4 1.1 0.1 -0.9 -1.1 0.0 -0.2 -0.2 -1.0 0.3
Fed-up feelings 3.1 5.7 12.7 2.9 2.2 -3.6 0.0 2.8 2.6 2.1 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.9 -0.8 -1.4 -0.8 0.0 -0.7 0.3 0.2 -1.3
Relative age voice broke 0.2 0.2 0.5 -0.7 0.3 -0.0 0.0 0.2 -0.6 0.7 -0.7
Taking other prescription medications 0.7 1.0 3.0 -0.9 -1.7 -0.3 0.0 -0.7 -1.0 -1.5 -0.9
Age when periods started (menarche) 0.3 0.6 1.7 -0.2 0.4 -1.3 0.0 0.5 1.1 1.1 -0.9
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.7 0.5 0.1 0.9 0.0 0.0 1.0 1.6 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.0 5.8 0.5 0.7 -1.1 0.0 0.6 2.4 -0.5 0.3
Tinnitus: Yes, but not now, but have in the past 1.8 1.9 5.0 -2.0 -0.1 2.2 0.0 -1.7 -1.5 -1.1 -0.4
Qualifications: CSEs or equivalent 0.2 0.3 0.7 0.6 0.8 0.8 0.0 0.0 0.1 0.6 0.3
Serious illness, injury or assault to yourself 1.7 2.1 5.9 -2.2 -1.1 0.8 0.0 -1.8 -1.0 -2.4 -0.4
High blood pressure 0.0 0.1 0.3 -0.4 -0.4 -0.4 0.0 0.2 -0.2 -0.4 -0.6
Hayfever, allergic rhinitis or eczema 1.7 3.6 6.7 -1.9 -2.0 1.9 0.0 -2.5 -2.0 -2.6 -0.2
Multivitamins +/- minerals 0.1 0.2 0.5 -0.6 0.5 0.3 0.0 -0.7 0.1 -0.2 0.4
Stomach or abdominal pain in last month 0.9 1.1 4.0 -0.7 -2.0 -0.3 0.0 -0.5 -1.1 -1.1 -1.1
Supplements: Glucosamine 0.2 0.3 0.9 0.4 -0.9 -0.1 0.0 -0.2 0.6 0.7 0.4
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.3 0.2 -0.4 -0.3 0.0 -0.5 -0.2 -0.5 0.3
Medication: Atenolol 0.4 0.5 2.8 -0.4 -0.3 0.1 0.0 -0.3 0.0 -1.0 1.7
Medication: Levothyroxine sodium 0.3 0.5 1.1 0.3 -1.1 -0.8 0.0 0.9 0.7 1.0 0.6
Sitting height 0.5 3.6 13.2 3.6 2.1 1.0 0.0 2.3 1.2 1.5 1.2
Chronic bronchitis/emphysema (father) 0.5 0.6 1.5 -0.3 -0.7 -1.1 0.0 -0.0 -0.3 -1.2 -1.2
High blood pressure (mother) 1.6 2.2 4.8 2.2 1.6 -1.5 0.0 1.8 1.8 0.6 1.1
Body mass index (BMI) 0.4 1.7 5.4 1.1 1.9 -1.5 0.0 2.3 0.6 -0.3 0.3
Impedance of leg (left) 0.2 1.0 2.4 0.4 -1.6 1.2 0.0 -1.4 0.5 1.2 0.3
Leg predicted mass (left) 0.7 3.8 10.7 2.5 3.0 -1.4 0.0 3.3 1.5 -0.0 0.4
Trunk fat mass 0.7 2.8 8.4 2.4 1.9 -0.6 0.0 2.9 0.9 0.3 1.9
Waist circumference 0.6 2.3 6.8 1.3 1.6 -1.9 0.0 2.6 1.1 0.3 -1.5
Number of incorrect matches in round 0.2 0.4 1.7 -1.3 -0.8 0.5 0.0 -0.6 -0.3 0.1 -0.3
Past tobacco smoking 0.8 1.5 5.0 1.5 1.6 -1.4 0.0 2.2 0.8 0.2 0.1
Alcohol usually taken with meals 0.6 1.0 3.0 1.1 -0.2 1.5 0.0 0.5 -0.2 1.2 1.7
Nervous feelings 1.1 2.1 5.4 2.0 0.7 -1.7 0.0 1.0 1.6 2.3 0.4
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 1.2 0.3 -0.9 -1.1 0.0 -0.7 -0.0 -0.3 -0.4
Hearing difficulty/problems with background noise 0.9 1.4 4.8 -1.7 -1.1 0.1 0.0 -2.2 -1.5 -0.5 -0.1
Hair/balding pattern: Pattern 2 1.6 2.1 7.9 2.8 2.1 -0.7 0.0 1.3 -0.1 1.1 0.8
Had menopause 0.9 1.1 3.8 -1.6 -1.9 0.0 0.0 -0.8 -0.6 -1.1 -0.4
Had other major operations 0.8 1.0 4.2 1.2 0.7 -2.0 0.0 1.2 0.5 0.2 0.1
Forced vital capacity (FVC) 1.4 5.2 13.7 3.7 3.2 -0.9 0.0 3.1 2.0 1.8 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 3.9 0.4 0.2 -0.5 0.0 0.3 2.0 -0.2 0.1
Ever unenthusiastic/disinterested for a whole week 1.6 2.0 4.1 -1.7 -1.4 -0.2 0.0 -1.1 -2.0 -1.5 -1.8
Qualifications: None of the above 0.4 0.8 3.1 -0.5 -1.1 0.4 0.0 -1.8 -1.3 -0.3 -0.4
Financial difficulties in last 2 years 2.3 3.1 9.4 -1.9 -2.1 0.0 0.0 -3.1 -1.5 -2.3 -0.5
Mouth/teeth dental problems 0.3 0.4 1.7 -0.3 -1.3 0.2 0.0 -0.0 0.0 -0.8 1.0
Heart attack 0.3 0.4 1.2 -0.5 0.9 0.7 0.0 -0.4 0.4 -0.0 -1.1
Allergy 2.8 6.3 11.9 3.0 3.2 -1.9 0.0 3.4 2.8 2.9 -0.0
Pain all over the body in last month 0.3 0.3 0.8 0.8 -0.9 -0.2 0.0 0.2 0.4 0.8 0.4
Diabetes (self-reported) 0.7 1.0 3.7 0.6 1.8 0.7 0.0 0.2 -0.7 -0.5 -1.9
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 5.0 -1.8 -1.1 1.3 0.0 -1.4 -0.8 -2.2 -0.3
Medication: Ramipril 0.4 0.5 1.6 0.4 0.7 -1.0 0.0 0.7 0.2 0.3 -1.3
Medication: Simvastatin 0.4 0.7 1.9 1.0 1.4 1.1 0.0 -0.2 -0.8 -0.5 -0.4
Fluid intelligence score 0.5 1.0 4.3 1.4 0.9 -0.2 0.0 2.1 0.6 -0.1 0.8
Illnesses of siblings 0.9 1.3 4.6 1.5 1.3 -0.1 0.0 1.0 0.7 2.1 0.5
Neuroticism score 2.0 4.2 10.4 2.4 1.8 -3.2 0.0 2.0 1.5 2.8 -0.8
Weight 0.9 4.4 13.2 2.9 2.7 -1.5 0.0 3.6 1.7 0.6 0.5
Impedance of arm (right) 0.7 3.5 8.0 -0.7 -2.8 2.7 0.0 -1.9 -1.2 0.1 2.7
Arm fat percentage (right) 0.4 1.5 5.3 1.3 0.9 -0.5 0.0 1.9 0.2 -0.3 2.3
Trunk fat-free mass 0.9 5.4 12.6 3.0 3.1 -2.1 0.0 3.5 2.5 0.7 -0.8
Hip circumference 1.0 4.1 11.4 2.9 2.2 -1.1 0.0 3.4 1.5 0.1 2.2
Time employed in main current job 2.4 2.8 5.3 2.2 1.5 -0.9 0.0 2.1 2.3 2.1 0.5
Alcohol intake versus 10 years previously 0.1 0.1 0.5 -0.1 0.3 -0.4 0.0 -0.2 -0.4 -0.7 -0.1
Father’s age at death 0.8 1.1 4.9 -2.2 -0.3 0.8 0.0 -0.7 -0.3 -1.2 1.1
Worrier / anxious feelings 1.7 3.2 6.3 2.1 1.5 -2.5 0.0 2.0 1.9 2.3 -0.3
Frequency of tiredness / lethargy in last 2 weeks 1.7 2.8 6.0 2.2 0.4 -2.4 0.0 1.7 2.1 1.8 -0.5
Falls in the last year 0.4 0.6 3.6 -0.3 -0.3 -0.6 0.0 0.1 0.3 0.6 -1.9
Hair/balding pattern: Pattern 3 1.1 1.6 3.2 -1.8 -1.7 1.8 0.0 -1.1 -0.8 -0.9 -0.8
Number of live births 0.5 0.7 2.2 0.8 -0.7 -1.0 0.0 -0.6 0.6 0.9 1.5
Forced expiratory volume in 1-second (FEV1) 2.6 8.8 21.3 4.6 3.9 -2.0 0.0 4.3 3.1 1.6 -0.1
Pulse rate 0.3 0.5 2.0 0.0 -0.1 -1.0 0.0 0.6 0.1 -1.0 -1.4
Happiness 0.4 0.5 1.5 -0.9 -1.2 -1.2 0.0 0.5 -0.0 0.4 -0.2
Noisy workplace 0.2 0.2 0.6 0.2 0.7 0.2 0.0 -0.2 -0.8 0.4 -0.6
Qualifications: A levels/AS levels or equivalent 0.5 1.2 2.6 0.7 0.8 -1.6 0.0 1.4 1.3 0.2 1.5
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.1 0.9 0.3 -0.6 0.0 0.5 0.6 -1.0 0.1
Mouth/teeth dental problems: Dentures 0.2 0.3 0.9 0.3 0.7 0.0 0.0 0.2 -0.3 -0.6 -0.9
Asthma 0.6 1.2 3.6 -1.0 -1.4 0.7 0.0 -1.9 -1.4 -0.5 0.3
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.4 -0.7 -1.2 0.0 0.0 -0.0 -0.1 -0.8 -0.4
Medication: Cholesterol lowering 0.4 0.6 2.3 1.2 1.5 0.7 0.0 0.1 0.0 -0.8 -0.0
Depression (self-reported) 1.4 1.7 4.0 -1.9 -1.4 -0.2 0.0 -1.7 -1.0 -0.5 -2.0
Medication: Lansoprazole 1.3 1.4 5.2 -1.4 -1.1 -0.8 0.0 -0.5 -0.3 -1.5 -2.3
Prospective memory result 0.6 0.8 2.4 -1.5 -0.6 0.9 0.0 -1.5 -0.3 0.3 -0.3
Lung cancer (father) 1.8 2.1 9.0 2.0 0.1 -3.0 0.0 1.0 1.4 0.1 0.9
Illnesses of mother 0.7 0.8 2.2 -1.5 -0.5 0.7 0.0 -1.3 -1.1 0.3 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.1 14.5 3.6 3.8 -1.7 0.0 3.5 2.3 0.3 -0.5
Pulse wave Arterial Stiffness index 1.1 1.3 6.3 0.2 1.6 0.2 0.0 0.7 1.0 -0.2 -2.5
Impedance of arm (left) 0.6 2.9 7.6 -0.7 -2.3 2.8 0.0 -1.4 -1.9 -0.2 2.1
Arm fat mass (right) 0.6 2.6 8.9 2.1 1.9 -1.3 0.0 3.0 0.9 0.2 1.3
Trunk predicted mass 0.9 4.9 11.7 2.9 2.9 -1.9 0.0 3.4 2.4 0.8 -0.8
Standing height 0.6 5.9 17.8 4.2 2.3 -0.1 0.0 3.5 2.8 2.1 0.4
Length of working week for main job 0.3 0.3 0.8 -0.0 -0.8 -0.7 0.0 0.2 0.9 -0.3 0.7
Exposure to tobacco smoke at home 0.1 0.2 0.9 -0.1 -0.4 -0.1 0.0 0.2 -0.3 -0.2 1.0
Breastfed as a baby 0.7 0.9 3.2 0.0 0.1 -1.8 0.0 1.2 0.8 1.2 0.0
Tense / ‘highly strung’ 0.4 0.6 1.3 0.2 -1.2 -0.8 0.0 -0.9 -0.9 0.1 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 4.1 -0.5 -0.4 0.1 0.0 -1.1 0.3 -1.1 -2.0
Hair/balding pattern: Pattern 4 0.1 0.3 1.4 -0.3 -0.2 0.4 0.0 -0.5 -0.7 -1.2 -0.2
Birth weight of first child 0.5 0.9 3.5 0.2 1.9 -1.1 0.0 1.3 0.4 -0.6 0.7
Peak expiratory flow (PEF) 2.2 5.1 11.5 3.4 2.9 -1.2 0.0 3.0 2.8 1.7 -0.5
Pulse wave reflection index 0.4 0.5 2.5 -0.4 0.2 0.4 0.0 -0.1 0.5 0.9 -1.6
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.9 0.6 0.6 -1.0 0.0 -0.2 0.0 0.8 -0.8
Loud music exposure frequency 2.0 2.2 8.5 1.6 0.4 -2.9 0.0 1.6 1.5 0.5 -1.2
Qualifications: O levels/GCSEs or equivalent 0.7 1.2 3.1 0.5 0.8 -0.6 0.0 1.0 1.6 1.2 1.8
Mouth/teeth dental problems: Bleeding gums 2.1 2.7 5.9 1.4 2.4 -1.9 0.0 1.9 1.7 1.9 -0.4
Blood clot in the leg (DVT) 0.4 0.5 1.5 -1.2 -0.5 0.1 0.0 -0.8 -0.9 -0.5 0.9
Medication: Paracetamol 0.3 0.5 1.4 0.9 0.3 -1.2 0.0 0.9 0.8 0.1 -0.8
Headache pain in last month 0.1 0.2 0.5 -0.4 0.6 -0.2 0.0 -0.3 -0.7 -0.5 0.1
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 1.0 -0.2 -0.5 -0.9 0.0 0.2 0.6 1.0 -0.2
Glaucoma (self-reported) 0.4 0.5 2.4 -0.5 -0.8 -0.1 0.0 0.2 -0.5 -0.8 -1.6
Gout (self-reported) 0.3 0.5 0.9 0.5 0.9 -0.2 0.0 0.9 1.0 0.9 -0.2
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.4 -0.3 -0.3 -0.5 0.0 0.5 0.3 0.7 0.1
Medication: Amlodipine 1.2 1.7 3.2 1.7 1.4 -1.4 0.0 1.6 0.8 1.8 -0.1
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.4 -0.7 -1.0 1.1 0.0 -1.6 -1.3 -0.4 -0.6
Birth weight 0.3 0.6 1.9 0.4 0.1 -0.5 0.0 0.9 1.2 1.4 -0.7
Chronic bronchitis/emphysema (mother) 0.5 0.5 1.6 1.2 0.4 0.8 0.0 0.5 1.3 -0.6 0.2
High blood pressure (siblings) 1.2 1.8 6.6 -1.4 -2.6 0.3 0.0 -1.8 -0.9 -1.2 0.4
Forced vital capacity (FVC), Best measure 1.2 4.3 10.9 3.3 3.3 -0.9 0.0 2.8 1.6 0.8 -0.5
Body fat percentage 0.4 1.7 4.4 1.8 1.2 -0.6 0.0 2.1 0.5 0.1 2.0
Leg fat percentage (right) 0.7 2.4 5.7 2.1 1.3 -1.6 0.0 2.4 1.8 0.4 1.1
Arm fat-free mass (right) 0.9 4.5 10.6 2.6 3.1 -1.9 0.0 3.2 1.9 0.5 -0.9
Exposure to tobacco smoke outside home 1.4 1.9 5.3 2.3 0.8 -1.3 0.0 0.8 1.0 1.9 1.5
Comparative body size at age 10 0.2 0.7 1.9 -1.4 -1.1 -0.3 0.0 -0.5 0.5 -1.2 0.5
Number of full brothers 1.3 1.7 4.0 -0.7 -1.8 1.0 0.0 -2.0 -1.3 -1.1 1.3
Worry too long after embarrassment 1.6 2.6 7.3 2.7 1.5 -1.1 0.0 1.0 0.8 1.8 2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 3.0 3.9 7.4 -2.7 -1.8 1.2 0.0 -2.7 -1.8 -2.6 -1.4
Wheeze or whistling in the chest in last year 0.5 1.0 3.7 -0.4 -1.4 0.3 0.0 -1.1 -1.9 -0.4 -0.7
Number of children fathered 0.3 0.4 1.4 0.5 -0.3 0.9 0.0 0.1 0.1 1.2 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 1.1 -0.4 0.3 -0.5 0.0 -0.6 -0.7 -1.0 -0.7
Age at first live birth 1.8 3.2 8.0 1.9 2.8 -0.6 0.0 2.6 1.6 1.9 -0.9
Pulse wave peak to peak time 1.0 1.2 6.4 0.1 -1.4 -0.2 0.0 -0.5 -0.9 0.3 2.5
Health satisfaction 2.0 2.6 4.7 -1.9 -1.9 1.3 0.0 -2.2 -1.6 -1.0 1.9
Shortness of breath walking on level ground 0.8 1.0 2.6 -0.8 -1.0 1.1 0.0 -1.6 -1.4 -0.5 0.4
Qualifications: College or University degree 0.2 0.6 1.2 0.4 -0.2 1.1 0.0 0.3 -1.1 -0.9 1.1
Eye problems/disorders: None of the above 1.2 1.4 5.2 1.0 1.5 -0.4 0.0 0.1 1.6 0.3 2.3
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.5 -0.9 -0.0 1.1 0.0 -0.8 -0.2 0.7 -1.2
Emphysema/chronic bronchitis 0.4 0.4 1.3 -0.2 -0.8 -1.1 0.0 0.1 -0.3 -0.7 -0.9
Medication for pain relief, constipation, heartburn 0.2 0.3 0.8 -0.5 0.9 0.5 0.0 0.0 -0.1 0.9 0.1
Neck or shoulder pain in last month 0.4 0.5 1.5 0.3 -0.6 -0.1 0.0 -0.4 -1.2 -1.0 1.0
Medication: Blood pressure 0.1 0.1 0.4 0.5 0.4 -0.1 0.0 0.3 -0.0 -0.6 0.6
Angina (self-reported) 0.6 0.8 3.0 1.7 0.5 0.1 0.0 -0.3 -0.1 0.4 1.7
Migraine (self-reported) 0.7 0.8 2.1 -1.1 -0.5 1.4 0.0 -1.4 -0.8 -0.5 0.2
Medication: Ibuprofen 0.2 0.2 0.5 -0.1 -0.6 -0.7 0.0 0.6 0.6 -0.2 -0.4
Medication: Allopurinol 0.8 1.0 2.4 0.4 1.2 -0.1 0.0 1.3 1.5 1.1 -1.2
Medication: Omeprazole 0.8 1.0 4.3 -1.0 -2.1 -0.3 0.0 -1.3 -0.4 -0.7 0.3
Medication: Seretide 50 evohaler 0.6 0.7 2.4 0.4 -0.2 1.2 0.0 -0.8 -0.2 -1.5 -1.1
Mean time to correctly identify matches 0.5 1.0 4.5 0.3 1.2 1.0 0.0 -0.6 -0.3 -0.3 2.1
Heart disease (mother) 1.9 2.3 4.7 1.6 1.9 -2.2 0.0 2.0 1.5 1.0 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.5 2.2 0.6 -0.5 -1.1 0.0 0.0 0.3 1.5 -0.5
Whole body fat mass 0.7 2.8 8.2 2.5 2.0 -1.0 0.0 2.9 1.0 0.3 1.6
Leg fat mass (right) 0.9 3.5 9.1 2.5 2.4 -1.4 0.0 3.0 1.8 0.4 1.3
Arm predicted mass (right) 1.1 5.8 13.5 3.0 3.6 -2.2 0.0 3.7 2.2 0.9 -1.1
Pulse rate, automated reading 0.5 1.7 8.0 -0.7 -1.2 -1.6 0.0 0.9 -0.1 -0.6 -2.8
Alcohol intake frequency. 1.7 4.0 12.2 -2.1 -1.8 1.4 0.0 -1.3 -3.5 -2.6 -1.3
Comparative height size at age 10 0.7 4.0 12.5 3.5 2.5 -0.7 0.0 2.6 2.0 1.2 0.9
Number of full sisters 1.2 1.5 3.0 -1.4 -1.6 0.4 0.0 -1.7 -1.0 -1.1 1.5
Suffer from ‘nerves’ 0.6 0.9 2.7 1.2 0.4 -1.3 0.0 0.6 0.6 1.6 -0.8
Overall health rating 1.1 2.3 6.2 -1.5 -2.4 -0.5 0.0 -1.3 -2.5 -1.3 -0.8
Chest pain or discomfort 1.4 2.0 4.2 -1.5 -2.0 0.2 0.0 -1.8 -1.7 -1.7 -0.8
Had major operations 0.6 0.8 4.1 0.5 0.0 -2.0 0.0 0.7 -0.9 -0.2 0.6
Age at last live birth 1.6 2.4 5.7 1.1 2.4 -0.4 0.0 1.5 2.1 2.3 -0.3
Family relationship satisfaction 2.2 2.7 9.0 -1.8 -2.2 0.7 0.0 -1.5 -3.0 -1.5 -0.1
Leg pain on walking 0.6 0.8 2.6 -1.1 -0.2 1.2 0.0 -1.6 -0.6 0.0 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 2.3 -0.6 -1.3 1.0 0.0 -0.9 0.0 -0.5 1.5
Commuting to job workplace: Car/motor vehicle 2.3 2.7 5.6 2.4 0.8 -0.6 0.0 1.5 2.2 2.2 1.6
Illness, injury, bereavement, stress in last 2 years 3.0 3.7 8.0 2.4 2.2 -1.1 0.0 2.8 2.0 2.3 1.0
Medication: Aspirin 0.2 0.2 1.1 0.6 0.4 -0.4 0.0 -0.0 -0.1 -1.0 0.3
Supplements: Vitamin C 0.5 0.6 2.7 -0.1 1.6 -0.0 0.0 0.4 1.2 0.4 0.2
Knee pain experienced in last month 0.3 0.4 1.3 0.1 -0.7 -0.2 0.0 -1.1 -1.0 0.7 0.3
Hypertension (Self-reported) 0.1 0.3 0.6 -0.7 -0.7 -0.0 0.0 -0.3 -0.7 -0.7 -0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.1 -0.0 -1.1 -0.3 0.0 -0.5 1.0 -0.8 -0.1
Illnesses of father: Heart disease 0.6 0.8 2.7 -0.2 -0.5 -0.3 0.0 -1.6 0.2 -1.6 1.1
Illnesses of siblings: Diabetes 0.9 1.1 5.3 -0.8 0.3 0.6 0.0 -1.2 -0.9 -2.3 -0.0
Smoking status: Previous 2.4 3.7 8.4 -2.4 -2.3 2.4 0.0 -2.9 -1.8 -1.0 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.7 6.1 2.5 1.2 -1.3 0.0 2.3 1.9 1.4 -1.1
Whole body fat-free mass 0.8 4.8 12.1 2.8 3.1 -1.9 0.0 3.5 2.1 0.4 -0.4
Leg fat-free mass (right) 0.6 3.0 8.7 2.2 2.8 -1.2 0.0 3.0 1.1 -0.2 0.2
Arm fat percentage (left) 0.4 1.4 4.3 1.2 1.2 -0.5 0.0 2.1 -0.1 -0.4 1.8
Average weekly red wine intake 0.4 0.6 2.8 0.3 0.2 -0.7 0.0 0.2 0.8 1.7 0.7
Handedness (chirality/laterality): Left-handed 0.9 1.1 4.0 -2.0 -0.5 0.2 0.0 -0.9 -0.6 -1.6 -0.9
Mood swings 0.2 0.4 1.1 0.5 -1.0 -0.5 0.0 -0.3 0.2 1.1 -0.8
Loneliness, isolation 0.2 0.3 1.2 0.1 1.1 -0.8 0.0 0.3 0.2 0.0 -0.8
Long-standing illness, disability or infirmity 1.9 2.9 10.6 -0.6 -2.0 0.1 0.0 -2.0 -1.8 -3.3 0.6
Ever had bowel cancer screening 0.2 0.2 0.8 0.1 0.2 -0.5 0.0 0.2 0.9 -0.8 -0.5
Diabetes diagnosed by doctor 0.5 0.9 2.9 1.2 1.7 -0.6 0.0 0.7 0.5 -0.2 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 0.7 -0.9 -0.9 0.0 0.0 -0.9 0.3 0.7 0.4
Friendships satisfaction 0.3 0.4 1.2 -0.1 -0.1 -0.3 0.0 0.2 -1.1 -0.9 1.0
Qualifications: nursing, teaching 0.4 0.6 2.8 -0.3 -0.5 1.7 0.0 0.0 -0.7 -0.5 0.9
Commuting to job workplace: Walk 0.3 0.3 1.1 -0.5 0.2 0.4 0.0 -1.0 -0.4 -0.8 -0.1
Eye problems/disorders: Cataract 0.8 0.9 6.2 0.2 0.1 -0.3 0.0 0.7 -0.3 0.6 -2.5
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 5.2 -0.8 -1.9 1.8 0.0 -1.9 -2.3 0.1 0.0
Medication for cholesterol 0.2 0.3 1.1 1.1 0.7 0.5 0.0 0.6 0.2 0.3 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.1 0.4 0.2 0.2 0.0 0.3 0.8 0.8 -1.0
Back pain experienced in last month 0.2 0.2 1.4 -0.5 -0.1 -1.2 0.0 -0.2 0.5 0.1 -0.2
Mineral and other dietary supplements 0.4 0.5 2.2 1.5 0.3 0.3 0.0 0.9 -0.1 -0.9 0.4
Breast cancer (self-reported) 0.8 1.0 1.9 1.4 1.4 -1.0 0.0 1.2 0.8 0.4 1.0
Asthma (self-reported) 0.8 1.7 4.7 -1.3 -1.7 1.0 0.0 -2.2 -1.6 -0.6 0.5
Osteoporosis (self-reported) 1.4 1.7 4.9 -1.0 -1.6 1.8 0.0 -1.5 -2.2 -0.1 0.1
Osteoarthritis (self-reported) 0.1 0.2 0.7 0.5 -0.1 -0.3 0.0 0.8 -0.0 0.2 -0.4
Medication: Aspirin 0.1 0.2 0.7 0.6 0.4 -0.2 0.0 0.0 -0.3 -0.8 0.1
Medication: Gliclazide 0.5 0.6 1.7 0.4 1.2 -1.3 0.0 0.9 0.7 -0.1 -0.3
Illnesses of father: None of the above (group 1) 1.2 1.5 7.9 0.7 0.9 -0.1 0.0 1.6 0.5 2.8 -0.4
Smoking status: Current 0.5 0.8 3.0 1.1 -0.5 -1.2 0.0 -0.1 1.7 0.8 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 7.4 1.8 2.7 -1.2 0.0 1.8 0.6 0.6 -1.0
Whole body water mass 0.9 5.1 12.6 3.0 3.2 -2.0 0.0 3.6 2.2 0.5 -0.3
Leg predicted mass (right) 0.6 3.2 9.2 2.3 2.9 -1.3 0.0 3.0 1.2 -0.1 0.2
Arm fat mass (left) 0.6 2.5 8.8 2.0 2.0 -1.1 0.0 3.0 0.8 0.2 1.1
Number of self-reported non-cancer illnesses 0.8 1.3 2.5 -1.6 -1.4 0.0 0.0 -1.5 -1.2 -1.6 -0.4
Average weekly champagne plus white wine intake 1.4 1.9 6.1 1.4 1.4 -0.6 0.0 1.2 1.5 2.5 1.2
Miserableness 1.5 2.5 6.0 0.9 1.1 -2.4 0.0 1.4 1.4 2.3 -1.7
Guilty feelings 0.9 1.3 3.3 1.6 0.8 -1.8 0.0 1.1 1.4 0.8 0.3
Wears glasses or contact lenses 0.5 0.5 2.6 0.0 -0.4 -0.8 0.0 0.5 0.9 0.2 1.6
Ever taken oral contraceptive pill 0.6 0.6 2.0 -0.7 -0.8 0.7 0.0 -1.4 -0.0 -0.8 0.9
Hearing aid user 0.6 0.6 3.5 0.7 1.9 0.7 0.0 0.5 0.2 -0.2 -0.4
Mother’s age at death 1.9 2.4 6.7 0.3 2.6 0.5 0.0 1.9 1.9 1.5 -1.6
Financial situation satisfaction 0.3 0.4 2.1 -0.2 0.6 -1.5 0.0 0.1 -0.3 -0.4 -0.6
Tinnitus: Yes, now most or all of the time 0.5 0.6 2.0 -0.1 -0.7 -0.5 0.0 -0.1 1.0 -1.4 -0.8
Commuting to job workplace: Public transport 1.3 1.5 3.8 -1.4 -1.1 -1.2 0.0 -0.2 -2.0 -1.6 -1.2
Eye problems/disorders: Glaucoma 0.4 0.5 2.0 -0.4 -0.6 0.3 0.0 -0.1 -1.2 -0.3 -1.4
Medication: Blood pressure 0.2 0.4 1.4 -1.2 -0.7 -0.7 0.0 -0.5 -0.4 0.1 -0.8
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.0 -0.3 0.1 0.2 0.0 -0.9 -0.8 -0.9 1.0
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.7 -0.8 -0.1 -0.1 0.0 -0.6 0.3 0.9 -0.5
High cholesterol (Self-reported) 0.6 1.1 2.6 -0.7 0.3 1.5 0.0 -1.1 -1.6 -1.2 -0.9
Medication: Bendroflumethiazide 0.7 1.1 3.2 0.6 1.4 -1.8 0.0 1.7 0.8 -0.0 0.2
Medication: Paracetamol 0.1 0.2 0.5 0.6 0.1 -0.7 0.0 0.5 0.4 -0.3 -0.6
Medication: Lisinopril 0.4 0.5 1.6 -0.9 -0.7 1.2 0.0 -0.2 -0.8 -0.2 -0.7
Medication: Atorvastatin 0.2 0.3 0.6 -0.7 -0.8 -0.6 0.0 -0.1 0.5 -0.6 -0.0
Illnesses of father: High blood pressure 2.2 2.7 6.9 -1.2 -2.4 0.2 0.0 -2.1 -0.7 -2.6 1.5
Alcohol drinker status: Never 3.5 4.2 9.3 -1.8 -2.7 1.7 0.0 -2.4 -3.0 -2.3 -0.4
Ever smoked 0.1 0.2 0.9 -0.5 -0.6 0.5 0.0 -0.9 -0.1 0.3 -0.1
Basal metabolic rate 0.9 4.9 13.0 3.0 3.0 -1.9 0.0 3.6 2.0 0.5 -0.0
Leg fat percentage (left) 0.5 1.9 4.4 1.9 1.3 -1.4 0.0 2.1 1.6 0.3 1.0
Arm fat-free mass (left) 1.0 5.1 11.4 2.8 3.1 -2.1 0.0 3.4 2.5 1.1 -0.7
Number of operations (self-reported) 0.5 0.8 2.7 0.6 0.3 -1.6 0.0 0.7 0.1 -0.8 1.4
Average weekly beer plus cider intake 0.0 0.1 0.2 0.2 0.4 -0.3 0.0 -0.1 0.0 0.3 0.1
Irritability 2.2 3.8 16.4 1.8 1.2 -4.0 0.0 2.0 1.8 1.0 -0.9
Risk taking 0.8 1.2 3.8 -0.6 -1.6 -0.4 0.0 -1.2 -1.0 -1.9 -0.7
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.7 -0.6 -0.6 1.3 0.0 -1.0 -0.7 0.2 -0.6
Fractured/broken bones in last 5 years 0.3 0.4 1.5 -0.2 0.2 -0.7 0.0 0.4 -1.1 -0.1 -1.2
Age started oral contraceptive pill 0.1 0.1 0.3 -0.1 0.3 0.5 0.0 0.2 -0.3 -0.4 0.5
Diastolic blood pressure, automated reading 0.2 0.7 1.5 -0.5 -0.1 -1.2 0.0 0.9 1.1 -1.1 -1.0
Ever depressed for a whole week 1.1 1.3 5.1 -1.0 -1.0 -0.1 0.0 -1.2 -1.3 -2.3 -0.4
Unable to work because of sickness or disability 3.9 5.1 10.7 -2.4 -3.3 1.0 0.0 -3.0 -2.9 -2.2 -1.1
Commuting to job workplace: Cycle 0.3 0.4 1.5 0.3 -0.1 -1.2 0.0 0.2 -0.9 0.2 -0.6
Myopia 0.9 1.2 4.4 -0.0 -1.5 -0.2 0.0 0.0 0.7 -2.1 1.7
Vascular/heart problems diagnosed by doctor 0.0 0.1 0.4 0.3 -0.0 0.2 0.0 0.0 0.3 0.3 0.7
Cholesterol lowering medication 0.2 0.3 0.7 -0.7 -0.2 0.3 0.0 -0.6 -0.2 -0.8 -0.7
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 4.5 -1.1 -2.1 -0.7 0.0 -1.2 -0.0 -1.4 0.1
Pain experienced in last month 0.6 1.0 4.0 -1.0 -0.8 2.0 0.0 -1.2 -0.4 -0.0 -0.7
Supplements: Calcium 2.0 2.2 6.3 -1.3 -0.6 2.5 0.0 -2.2 -1.9 -0.6 0.8
Basal cell carcinoma (self-reported) 0.3 0.4 1.6 0.3 -0.5 0.9 0.0 0.0 0.1 1.3 0.6
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.1 -0.5 0.7 0.6 0.0 -0.3 0.5 0.0 -1.0
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.6 -1.3 -0.9 0.1 0.0 -0.9 -1.1 -1.0 1.1
Heart disease (siblings) 0.5 0.6 2.1 -0.0 -1.1 0.7 0.0 -0.8 -0.8 -1.5 0.0
Alcohol drinker status: Previous 1.8 2.0 6.0 -1.8 -1.8 0.5 0.0 -1.2 -2.5 -1.2 -0.8
Pack years of smoking 0.3 0.4 1.2 0.1 -0.4 -1.1 0.0 0.1 0.6 -0.8 -1.0
Impedance of whole body 0.5 2.6 6.1 -0.3 -2.4 2.5 0.0 -1.9 -1.0 0.6 1.9
Leg fat mass (left) 0.8 3.3 8.6 2.4 2.4 -1.4 0.0 2.9 1.7 0.4 1.1
Arm predicted mass (left) 1.1 5.6 13.0 3.1 3.2 -2.2 0.0 3.6 2.5 0.9 -0.6