Hub : Genes

APPL2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1453	0.0500	2.2e-03	0.013	NA	0.028	NA	0.013	3.1e-02	NA	2.6e-03	NA	3.2e-02
2	GTEx	Brain Cerebellar Hemisphere	0.3010	0.0980	2.4e-04	0.152	NA	0.086	NA	0.120	1.0e-04	NA	3.3e-03	NA	5.7e-04
3	GTEx	Brain Cerebellum	0.2690	0.0700	9.0e-06	0.286	NA	0.204	NA	0.247	4.4e-09	NA	1.2e-06	NA	6.3e-08
4	GTEx	Cells Transformed fibroblasts	0.1960	0.0410	6.7e-11	0.236	NA	0.230	NA	0.242	1.1e-17	NA	3.5e-17	NA	4.1e-18
5	GTEx	Esophagus Gastroesophageal Junction	0.2240	0.0750	6.9e-04	0.064	NA	0.042	NA	0.074	2.5e-03	NA	1.2e-02	NA	1.2e-03
6	GTEx	Esophagus Muscularis	0.1040	0.0490	7.5e-03	0.021	NA	0.002	NA	0.012	1.9e-02	NA	2.5e-01	NA	5.6e-02
7	GTEx	Whole Blood	0.0870	0.0260	4.4e-06	0.101	NA	0.105	NA	0.109	1.5e-09	NA	6.6e-10	NA	3.3e-10
8	NTR	Blood	0.0276	0.0099	2.9e-04	0.015	0.012	0.008	0.013	0.012	1.1e-05	5.8e-05	1.2e-03	3.5e-05	5.7e-05
9	YFS	Blood	0.1487	0.0227	0.0e+00	0.177	0.223	0.229	0.226	0.230	2.1e-55	3.5e-71	1.9e-73	1.7e-72	5.3e-74
10	TCGA	Bladder Urothelial Carcinoma	0.0480	0.0250	1.3e-03	0.024	0.019	0.017	NA	0.016	3.4e-03	9.1e-03	1.2e-02	NA	1.6e-02
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0452	0.0320	2.8e-03	0.017	0.020	0.026	NA	0.015	4.5e-03	2.5e-03	5.7e-04	NA	7.5e-03
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0325	0.0172	8.4e-04	0.025	0.035	0.036	NA	0.035	7.7e-04	7.6e-05	6.0e-05	NA	8.2e-05
13	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1200	0.0620	1.1e-04	0.050	0.077	0.030	NA	0.049	7.3e-04	3.4e-05	8.0e-03	NA	8.2e-04
14	TCGA	Thyroid Carcinoma	0.0960	0.0390	5.9e-09	0.064	0.080	0.098	NA	0.094	7.4e-07	3.3e-08	9.0e-10	NA	1.9e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	1.2	1.9	4.2	1.9	-0.9	-0.9	2.0	1.6	1.9	-1.4	-0.3	-0.9	2.1	0.1	-0.3	-0.4	2.1
Bipolar Disorder or Schizophrenia	0.3	0.7	1.9	-0.0	-0.0	-1.1	0.9	1.0	1.0	-1.0	-0.1	-0.7	0.8	0.8	0.6	0.0	1.4
Depressed Affect (Nagel 2018)	0.5	1.0	3.2	-0.3	-1.4	-1.5	0.0	-0.9	-0.1	-1.3	-0.4	-1.4	-0.0	0.8	1.8	0.9	0.8
Depression (Nagel 2018)	0.3	0.5	1.8	-0.4	0.8	0.5	-0.8	-1.3	-1.1	0.4	-0.0	-0.1	-0.7	0.0	0.1	0.6	-0.9
Intelligence (Savage-Jansen 2018)	0.8	2.3	8.1	-0.8	0.1	0.1	0.1	-1.7	-0.9	-1.0	-2.8	-2.1	-0.5	2.6	1.8	2.1	0.4
Neuroticism (Nagel 2018)	0.5	1.3	3.5	-0.3	-1.5	-1.7	0.4	-0.4	0.1	-1.6	-0.6	-1.7	0.5	0.5	1.9	1.2	1.0
Schizophrenia (2018)	0.2	0.4	2.1	-1.5	0.7	-0.7	-0.4	-0.0	-0.2	-0.1	0.1	-0.2	-0.6	1.0	0.9	0.4	0.1
Schizophrenia vs Biploar Disorder	1.5	2.0	4.7	-0.7	1.4	0.9	-1.9	-1.0	-1.9	1.7	1.2	1.6	-2.2	-1.5	0.2	-0.2	-1.6
Worry (Nagel 2018)	0.4	0.9	2.0	-1.0	-1.2	-1.3	0.6	0.5	0.5	-1.1	-0.6	-1.4	0.9	0.4	1.0	1.0	0.7
Alzheimer’s Disease (in mother)	0.1	0.2	0.9	0.5	0.2	-0.5	-0.3	0.4	-0.1	-0.3	-0.2	-0.3	0.1	1.0	0.3	0.4	-0.2
Alzheimer’s Disease (in father)	1.9	2.0	4.5	-0.6	-1.5	-1.6	1.8	1.0	1.5	-1.8	0.1	-1.6	1.7	1.2	1.3	0.8	2.1
Alzheimer’s Disease (including proxy)	0.4	0.6	1.5	0.6	-0.5	-1.0	0.1	-0.3	-0.4	-1.0	-0.2	-1.2	0.5	0.9	1.0	1.2	0.5
Crohns Disease (2017)	0.2	0.4	2.5	-1.6	0.6	0.4	-0.5	-0.2	-0.6	0.7	-0.3	0.1	-0.3	0.3	-0.3	0.1	-0.7
Irritable Bowel Disease (IBD)	1.3	3.0	5.8	-2.0	2.3	2.0	-1.8	-0.8	-2.1	2.4	0.9	1.5	-2.0	-1.0	-1.2	-1.2	-2.0
Ulcerative Colitis (UC)	1.5	2.9	6.6	-1.7	2.6	1.9	-1.4	-0.6	-2.0	2.3	0.9	1.5	-2.2	-1.2	-0.9	-1.7	-1.4
Major Depression (MDD)	1.2	1.4	3.2	0.4	-1.3	-1.2	1.7	1.2	1.5	-1.3	0.5	-1.2	1.5	0.4	0.5	0.3	1.8
Reaction Time	0.0	0.1	0.4	0.3	-0.1	-0.2	0.4	-0.2	0.7	-0.2	-0.1	-0.2	0.4	0.3	-0.2	0.2	0.0
Verbal and Numeric Reasoning (VNR)	0.8	2.0	6.7	-0.2	-0.2	-0.4	0.2	-1.1	-0.6	-1.0	-2.6	-1.9	0.0	2.6	1.6	2.3	0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	1.4	1.8	5.3	-1.2	1.2	1.0	-2.1	-1.3	-2.3	0.8	0.4	0.4	-1.9	1.4	0.4	0.4	-1.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.2	0.2	0.9	-0.4	-0.4	-0.7	-0.3	0.3	-0.5	-0.3	-0.2	-0.3	-0.5	-0.6	0.9	-0.3	0.6
Bipolar Disorder (2011)	2.1	2.0	5.2	-0.0	-0.4	-0.6	2.1	2.0	2.2	-1.4	0.1	-0.8	1.9	1.6	-0.0	-0.9	2.3
Body Mass Index (BMI) (2010)	1.1	1.5	3.0	0.2	1.7	1.7	-1.1	-0.9	-0.8	1.7	0.7	1.6	-1.1	-0.0	-1.5	-0.7	-1.7
Coronary Artery Disease (CAD)	0.6	0.8	1.8	0.9	0.9	0.8	1.3	1.1	1.0	0.6	0.6	0.4	1.1	0.0	-1.1	-1.0	0.5
Crohns Disease (2012)	0.1	0.1	0.6	-0.8	-0.2	-0.3	-0.3	0.4	-0.2	0.2	-0.3	-0.0	0.2	-0.4	-0.0	0.4	-0.6
Mean Putamen Volume	0.8	1.0	2.3	0.8	-1.2	-1.4	0.8	1.2	0.8	-1.5	-0.3	-0.8	1.0	0.1	1.0	0.6	1.1
Fasting Glucose	0.3	0.4	1.7	0.5	-0.8	-1.3	-0.0	0.3	0.0	-0.6	0.0	-0.3	-0.0	0.0	1.3	0.4	0.6
HbA1C	0.6	0.7	1.6	0.5	-1.2	-1.0	0.9	0.7	1.0	-1.1	-0.3	-0.5	0.9	0.6	0.5	0.1	1.2
HDL Cholesterol	0.2	0.4	1.8	-0.9	-1.4	-0.8	0.2	0.1	0.0	-0.6	0.0	-0.7	0.6	-0.5	0.3	0.8	0.3
LDL Cholesterol	0.5	0.8	2.5	-0.3	-0.2	-0.5	1.2	1.2	1.6	-0.1	0.3	0.3	1.1	-0.1	-0.9	-1.2	1.3
Lupus	0.9	1.4	5.7	-1.6	-0.3	-0.6	-0.7	-2.4	-1.2	-0.4	-0.4	-0.8	-1.1	-0.6	1.8	1.8	-0.3
Neuroticism (2016)	0.3	0.4	2.4	-0.0	0.1	-0.0	-0.8	-0.3	-0.1	0.9	0.9	0.6	-0.3	0.1	-0.7	0.5	-1.6
Primary Biliary Cirrhosis	0.4	0.6	2.0	0.7	0.2	0.2	0.6	0.9	1.0	0.3	1.1	0.9	0.7	-0.2	-1.4	-1.1	0.1
Rheumatoid Arthritis	1.4	1.9	7.3	1.2	-0.3	-0.6	2.2	1.9	2.7	-0.2	-0.8	-0.2	2.2	0.9	-1.3	-0.4	0.9
Schizophrenia (2014)	0.3	0.6	1.9	-0.4	-0.0	-1.1	0.6	1.4	1.0	-0.7	0.2	-0.3	0.6	0.8	0.6	-0.4	1.1
Triglycerides	0.4	0.6	2.7	0.2	1.6	0.8	-0.0	-0.5	-0.3	0.7	0.7	0.9	-0.8	-0.2	-0.5	-1.3	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.8	-0.3	0.4	0.5	-0.4	-0.1	-0.9	0.3	0.9	0.5	-0.6	-0.7	-0.2	-0.4	-0.2
Ulcerative Colitis	2.1	3.0	5.1	-1.3	2.2	1.7	-1.8	-0.7	-2.0	2.3	1.4	2.1	-2.2	-1.4	-1.0	-1.6	-1.8
Blood Eosinophil Count	0.1	0.8	3.1	-1.2	0.5	1.1	-1.1	-1.8	-1.3	0.5	-0.4	0.2	-0.9	0.0	0.0	0.7	-1.1
Blood Platelet Count	0.1	1.2	4.5	-0.1	-0.4	-0.1	1.2	1.9	2.1	-0.2	1.2	0.0	1.4	0.5	-0.9	-0.9	1.1
Blood Red Count	0.3	3.2	8.2	-0.4	1.9	1.9	-2.0	-2.9	-2.8	1.8	-0.6	0.4	-2.1	-1.0	-0.2	1.3	-2.5
Blood White Count	0.0	0.2	1.2	-0.3	0.1	-0.8	-0.2	0.4	-0.0	-0.1	1.1	-0.1	0.2	0.2	0.5	-0.1	0.2
Heel T-Score	0.2	1.3	6.8	-2.6	-0.9	-1.2	-0.6	0.1	-0.4	-1.5	0.6	-1.1	-0.5	0.4	1.9	0.3	1.0
BMI	1.4	8.4	21.9	-0.1	2.0	1.8	-3.5	-1.2	-2.1	3.0	4.7	4.2	-2.9	-4.0	-1.9	-1.9	-3.5
Height	0.3	6.7	15.0	3.9	-2.0	-2.7	1.9	1.5	1.1	-3.4	-2.8	-3.0	1.4	2.7	2.9	0.5	3.7
Waist Hip Ratio (WHR)	1.5	6.6	12.3	1.3	-2.5	-3.5	2.5	1.7	2.2	-3.4	-1.7	-3.3	2.4	2.4	2.9	1.4	3.5
Systolic Blood Pressure	0.7	3.6	11.1	-0.4	2.6	1.5	0.2	1.4	0.6	1.8	2.9	2.8	-0.0	-1.0	-2.6	-3.3	-0.2
Smoking Status	0.7	1.8	4.1	-0.3	-1.1	-1.4	1.6	1.9	2.0	-1.5	0.3	-0.8	1.4	1.1	0.9	-0.5	2.0
Allergy or Eczema	0.9	2.4	4.5	1.4	-1.8	-1.9	1.1	1.2	0.9	-2.1	-1.3	-2.0	1.2	1.0	2.0	0.8	2.1
Cardiovascular Disease	0.3	0.9	2.8	-0.3	0.7	1.0	-0.1	-0.1	-0.1	0.9	1.7	1.1	-0.0	-1.5	-1.5	-1.2	-0.5
Hypothyroidism (self reported)	0.4	0.9	2.4	-0.7	-0.7	-1.2	0.4	-0.1	0.0	-1.3	-1.1	-1.3	0.4	0.2	1.5	1.4	0.8
Respiratory disease	1.5	3.3	6.8	1.7	-2.1	-2.0	1.8	1.8	2.0	-2.6	-0.7	-1.9	2.2	1.1	1.4	0.7	2.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	3.8	0.1	-0.9	-1.1	0.3	0.7	0.5	-0.9	1.9	-0.1	0.6	-0.3	0.8	0.2	0.9
Lung FEV1/FVC ratio	1.2	6.2	14.3	-1.2	2.4	2.6	-1.4	0.2	-0.5	3.3	3.1	3.8	-1.6	-2.9	-3.3	-2.7	-2.4
Lung FVC	0.3	1.4	4.2	-1.9	1.2	1.1	-1.0	-2.1	-1.3	1.1	-0.4	0.2	-1.0	-0.2	-0.6	0.7	-1.5
Neuroticism	0.3	0.7	2.2	-0.2	-1.3	-1.5	-0.5	-0.8	-0.3	-0.9	-0.1	-0.8	-0.2	-0.4	1.4	0.8	0.3
Chronotype (morning person)	0.3	0.7	1.8	0.6	1.0	0.8	0.9	0.7	0.8	0.6	-0.0	0.4	0.5	1.2	-1.3	-1.1	0.4
Hair Pigment	0.0	1.2	3.9	2.0	-1.4	-0.8	0.0	1.5	1.1	-0.2	1.8	1.2	0.5	0.3	-0.7	-1.4	0.2
Tanning	0.0	0.5	1.3	-1.1	-0.4	0.4	1.1	0.6	0.9	-0.2	-0.8	-0.6	0.8	-0.4	-0.5	-0.3	0.6
Hand grip strength (left)	0.4	1.0	5.9	2.4	1.0	0.5	-0.5	-0.1	-0.9	0.8	0.5	0.9	-1.0	-0.6	-0.4	-1.4	-0.0
Number of treatments/medications taken	0.2	0.4	3.8	-2.0	0.2	0.3	0.3	0.5	0.4	-0.2	-0.1	-0.3	0.4	0.4	-0.0	0.6	-0.2
Average weekly spirits intake	0.9	1.2	4.6	-1.2	0.5	0.8	-1.0	-1.2	-1.2	1.3	0.0	0.8	-1.4	-2.2	-0.3	-0.3	-1.1
Sensitivity / hurt feelings	0.3	0.5	1.4	0.4	-1.2	-0.9	0.5	1.0	0.8	-0.8	0.9	-0.0	0.9	0.4	0.1	-0.2	0.5
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.2	-0.3	0.2	-0.4	-0.5	-1.1	-0.4	0.1	0.2	-0.2	-0.3	0.4	0.4	0.9	-0.6
Hearing difficulty/problems: Yes	2.8	4.2	13.7	0.7	-2.5	-2.3	-0.7	-1.5	-1.1	-2.2	-1.7	-2.5	-0.2	2.4	3.2	3.7	0.1
Relative age of first facial hair	0.3	0.6	2.0	0.3	-1.4	-0.5	0.5	1.2	1.0	-0.8	0.3	-0.3	1.0	-0.2	-0.2	-0.6	1.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	4.0	-0.1	-0.2	-1.1	0.2	0.1	-0.2	-0.7	-2.0	-1.3	0.1	0.9	1.1	0.4	0.7
Ever used hormone-replacement therapy (HRT)	2.1	2.7	10.6	0.4	-1.6	-0.4	2.1	3.3	2.5	-0.5	0.8	0.4	2.5	0.3	-1.4	-1.6	1.4
Ever had hysterectomy (womb removed)	0.8	0.9	2.8	-0.2	1.7	1.6	-0.3	-0.8	-0.8	1.5	-0.3	1.0	-0.6	0.4	-1.0	-0.6	-0.9
Systolic blood pressure, automated reading	1.2	3.4	9.7	0.4	2.2	1.5	-0.7	1.0	-0.2	2.0	2.8	3.1	-0.8	-1.5	-2.2	-3.1	-0.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	-0.7	0.5	0.3	0.3	0.5	0.1	0.7	0.1	0.0	0.3	-0.3	-0.9	-0.2	-0.3
Angina	0.1	0.2	0.6	0.5	0.2	0.0	0.8	0.6	0.5	-0.1	-0.5	-0.4	0.6	-0.1	-0.2	-0.2	0.5
Medication for hormone replacement therapy	0.4	0.4	1.9	-0.0	-0.7	-0.4	0.6	1.4	0.9	0.0	0.2	0.1	0.9	0.6	-0.6	-0.1	0.0
Vitamin and mineral supplements	0.2	0.3	1.3	0.4	1.1	0.6	0.2	-0.0	-0.1	0.5	-1.2	-0.4	-0.0	0.6	-0.6	0.2	-0.4
Supplements: Zinc	5.0	5.4	14.6	-0.4	1.4	1.7	-3.4	-3.7	-3.8	1.8	-0.1	1.1	-3.5	-2.2	0.7	0.8	-2.8
Medication: Co-codamol	0.4	0.5	2.0	0.4	0.7	1.4	-0.0	-0.7	-0.4	0.9	0.3	-0.0	-0.0	0.5	-1.0	0.7	-1.1
Medication: Metformin	0.8	1.1	2.1	0.0	-1.2	-1.4	1.0	1.4	1.2	-1.1	1.2	-0.9	1.1	0.6	0.8	0.1	1.4
Diabetes (father)	0.2	0.3	0.9	0.9	-0.0	-0.7	-0.5	-0.0	-0.5	-0.3	-0.1	-0.1	-0.6	0.7	1.0	0.0	0.3
Diabetes (mother)	0.4	0.5	1.9	-0.2	-0.2	-0.5	1.1	1.4	0.8	-0.7	0.4	-0.5	1.1	0.7	0.1	-0.1	0.9
Severe depression (siblings)	0.6	0.7	1.7	0.2	1.1	1.3	-0.2	-1.1	-0.9	1.1	-0.3	0.3	-0.4	0.7	-0.6	1.0	-1.3
Pack years adult smoking proportion	1.4	2.1	5.1	-0.1	1.2	0.7	-1.9	-1.5	-1.3	1.4	2.2	2.1	-1.9	-1.0	-0.4	-0.3	-1.9
Impedance of leg (right)	3.4	16.2	27.2	0.1	-4.6	-4.0	4.9	4.0	4.7	-5.2	-3.4	-4.3	5.2	2.8	2.6	1.9	5.0
Leg fat-free mass (left)	1.7	8.8	15.7	0.6	4.0	3.2	-3.3	-2.2	-3.3	3.8	2.6	3.3	-3.6	-2.1	-2.2	-2.2	-3.3
Trunk fat percentage	0.4	1.6	9.9	0.2	0.2	0.3	-0.5	0.9	0.4	0.8	3.1	1.8	0.2	-1.8	-1.3	-0.8	-1.1
Hand grip strength (right)	0.3	0.8	3.3	1.8	1.2	0.4	0.0	0.5	-0.3	0.5	-0.1	0.6	-0.7	-0.9	-0.4	-1.8	0.6
Townsend deprivation index at recruitment	0.3	0.4	1.7	0.4	0.7	-0.1	-0.3	0.3	0.1	-0.0	1.0	0.6	-0.7	-0.6	0.2	-1.3	0.6
Current tobacco smoking	0.3	0.5	1.4	0.2	-0.5	-0.7	0.7	1.2	1.1	-0.6	0.8	0.3	0.6	0.5	0.2	-0.7	1.0
Average weekly fortified wine intake	0.1	0.2	1.5	-1.2	-0.4	-0.2	-0.1	-0.1	0.1	-0.2	0.1	-0.1	-0.2	-0.4	0.6	0.1	0.0
Maternal smoking around birth	1.1	1.6	5.0	-0.1	-0.2	0.7	1.1	1.3	1.9	0.6	1.8	1.4	1.4	-0.8	-2.2	-1.7	0.2
Fed-up feelings	0.4	0.7	1.6	-0.7	-0.5	-0.6	-0.3	-1.2	-0.3	-0.7	-1.0	-1.2	-0.3	1.3	1.2	1.1	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.4	0.4	0.3	0.4	0.0	-1.2	-0.2	0.1	-0.1	-0.2	0.0	0.3	0.0	0.9	-0.4
Relative age voice broke	0.8	1.3	2.5	-0.7	-1.0	-1.2	1.2	1.2	1.3	-1.2	-0.2	-1.2	1.6	1.6	0.5	0.8	1.2
Taking other prescription medications	0.2	0.3	0.7	-0.5	-0.3	-0.4	0.6	0.3	0.4	-0.6	-0.6	-0.8	0.3	0.4	0.8	0.3	0.8
Age when periods started (menarche)	0.4	1.0	3.5	1.7	0.2	1.7	1.0	0.4	0.9	0.5	-0.2	0.3	1.1	0.1	-1.9	-0.8	-0.0
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.8	-0.1	-1.4	-1.4	1.0	0.4	0.7	-1.2	-1.4	-1.4	1.2	2.0	0.8	1.1	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	5.8	-2.4	1.1	0.1	0.0	-0.7	-0.5	0.1	-0.6	-0.7	-0.6	-0.5	0.7	0.4	0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.3	0.4	-0.3	-0.9	-0.7	-0.3	-0.7	-0.8	-1.3	-0.8	-0.4	0.9	1.5	1.1	-0.0
Qualifications: CSEs or equivalent	0.6	0.8	3.5	0.5	-0.2	-0.6	0.6	1.9	1.4	-0.3	1.3	0.7	0.7	0.3	-0.3	-1.3	0.8
Serious illness, injury or assault to yourself	1.8	2.1	5.4	0.6	-2.1	-2.3	0.6	0.9	0.7	-2.1	-0.7	-1.6	1.0	1.4	1.9	1.3	1.4
High blood pressure	0.3	0.8	3.6	-1.9	1.3	0.8	-0.2	-1.0	-0.5	0.5	1.3	0.6	-0.6	-0.8	-0.3	-0.1	-0.4
Hayfever, allergic rhinitis or eczema	1.4	3.1	5.6	1.6	-2.4	-2.1	1.6	2.0	1.7	-2.2	-0.5	-1.9	1.8	1.5	1.5	0.5	2.3
Multivitamins +/- minerals	0.6	0.8	4.2	-0.2	-0.4	0.3	-0.8	-0.9	-0.3	0.5	2.0	1.1	-0.6	-1.6	-0.5	-0.5	-0.5
Stomach or abdominal pain in last month	0.3	0.4	2.6	-1.6	0.4	0.3	-0.5	-0.6	-0.5	0.7	-0.2	-0.2	-0.3	0.6	-0.3	0.3	-0.9
Supplements: Glucosamine	0.4	0.5	1.4	0.8	0.7	0.1	-0.6	-0.9	-0.7	0.6	1.2	0.8	-0.9	-0.3	-0.1	-0.2	-0.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.3	-0.7	0.2	0.2	0.8	-0.2	0.1	-0.3	-1.1	-1.1	0.6	1.1	0.2	0.9	0.4
Medication: Atenolol	0.3	0.4	1.8	1.4	0.3	0.2	0.9	0.7	0.4	-0.3	-0.6	-0.5	0.5	0.6	0.2	-0.1	0.6
Medication: Levothyroxine sodium	0.1	0.2	1.0	-0.5	0.2	-0.3	0.6	0.6	0.4	-0.3	-0.5	-0.4	0.2	-1.0	0.5	-0.2	0.7
Sitting height	1.0	6.9	17.4	-0.2	4.2	3.8	-2.1	-1.7	-2.5	3.7	0.7	2.6	-2.8	-1.5	-2.7	-2.3	-2.7
Chronic bronchitis/emphysema (father)	1.5	1.8	6.1	-1.1	0.5	0.3	-1.9	-1.1	-1.2	1.2	2.5	1.9	-1.7	-0.7	-0.2	-0.3	-1.6
High blood pressure (mother)	0.2	0.3	1.3	0.4	0.8	0.4	0.3	0.2	0.4	0.4	1.1	0.6	0.3	0.7	-0.8	-0.5	-0.1
Body mass index (BMI)	2.0	8.4	19.8	-0.3	2.7	2.5	-3.2	-1.7	-2.2	3.4	4.5	4.0	-2.9	-3.2	-2.3	-1.8	-3.5
Impedance of leg (left)	3.3	16.0	27.7	0.2	-4.6	-4.0	5.0	4.3	4.8	-5.1	-3.0	-4.0	5.3	2.5	2.5	1.7	5.1
Leg predicted mass (left)	1.8	9.4	16.7	0.5	4.1	3.3	-3.5	-2.2	-3.4	3.9	2.7	3.4	-3.8	-2.3	-2.3	-2.3	-3.3
Trunk fat mass	0.6	2.6	11.1	0.3	1.2	1.0	-1.3	0.2	-0.4	1.6	3.3	2.4	-0.8	-2.2	-1.6	-1.3	-1.7
Waist circumference	0.7	2.4	8.6	0.8	1.4	1.0	-1.7	-0.5	-1.0	1.6	2.9	2.2	-1.3	-1.9	-1.1	-1.1	-1.6
Number of incorrect matches in round	1.2	1.9	4.9	1.3	0.0	0.8	2.2	1.5	2.2	0.4	-0.6	0.2	1.7	-0.2	-2.0	-1.9	1.2
Past tobacco smoking	1.2	2.1	3.5	-0.7	1.3	1.2	-1.9	-0.8	-1.6	1.6	1.6	1.9	-1.7	-1.9	-0.9	-0.7	-1.9
Alcohol usually taken with meals	0.4	0.6	3.3	0.0	-0.4	0.1	1.2	0.3	0.7	-0.3	-1.8	-1.0	0.8	-0.4	-0.2	-0.2	0.9
Nervous feelings	0.7	1.4	11.5	-3.4	-0.1	-0.3	-1.0	-0.8	-0.5	0.6	1.2	0.5	-0.5	-1.0	-0.1	0.6	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.6	-0.3	-0.8	-0.8	-0.5	-1.6	-0.4	-0.7	0.0	-0.5	-0.4	0.2	1.1	1.4	-0.3
Hearing difficulty/problems with background noise	3.0	4.7	11.8	-0.4	-3.4	-3.3	0.4	-0.2	0.7	-3.2	-0.7	-2.6	1.0	1.7	3.2	3.1	1.4
Hair/balding pattern: Pattern 2	0.7	0.9	3.4	0.3	-1.5	-1.5	-0.1	-0.1	-0.1	-1.3	-0.6	-1.1	-0.1	-0.1	1.9	0.8	1.0
Had menopause	0.2	0.3	2.1	1.5	-0.5	-0.1	0.7	0.6	0.4	-0.3	-0.4	-0.0	0.5	-0.3	0.1	0.0	0.5
Had other major operations	0.9	1.0	2.3	-1.1	-0.5	-1.3	0.9	0.8	0.6	-1.1	-1.4	-1.5	0.5	-0.2	1.4	0.5	1.4
Forced vital capacity (FVC)	0.3	1.3	5.9	-1.1	2.4	1.4	-0.6	-0.9	-1.3	1.5	-0.8	0.4	-1.4	-0.3	-0.7	-1.0	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	6.4	-2.5	0.5	-0.7	0.8	0.3	0.4	-1.0	-1.7	-1.4	0.2	0.1	1.3	0.1	1.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.4	1.2	-0.4	-1.0	-0.3	-0.4	-0.2	-1.1	0.5	-0.2	-0.1	0.7	1.2	0.8	0.2
Qualifications: None of the above	0.8	1.6	5.2	-1.0	0.6	1.1	-1.0	-0.4	-0.1	1.1	2.3	2.0	-0.5	-1.9	-1.5	-0.7	-1.4
Financial difficulties in last 2 years	0.3	0.4	2.3	0.0	-0.6	-1.5	-0.3	0.1	-0.2	-0.4	-0.2	-0.6	0.0	-0.0	1.2	0.6	0.2
Mouth/teeth dental problems	0.8	1.2	2.8	1.0	-0.5	-0.0	-1.5	-0.2	-0.7	0.8	1.7	1.6	-1.3	-1.7	-0.2	-0.9	-0.9
Heart attack	0.4	0.5	1.6	-0.6	1.3	0.4	-0.6	-0.5	-1.1	0.6	-0.8	0.0	-1.2	-0.0	0.7	-0.3	-0.2
Allergy	1.1	2.6	5.4	-2.2	2.3	1.8	-1.2	-1.2	-1.3	2.1	-0.0	1.7	-1.7	-1.7	-1.4	-1.2	-1.5
Pain all over the body in last month	0.5	0.5	1.7	1.3	0.4	0.5	0.6	1.0	1.0	0.5	0.1	0.6	0.6	0.5	-1.1	-0.9	-0.0
Diabetes (self-reported)	0.3	0.4	1.8	0.1	-0.5	-0.8	-0.6	-0.3	-0.4	-0.3	1.3	-0.4	-0.3	0.0	0.9	1.0	-0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	2.4	0.3	-1.0	-1.1	0.6	1.3	0.6	-1.3	-0.4	-1.1	0.4	1.5	1.5	0.2	1.3
Medication: Ramipril	0.5	0.6	2.0	-1.0	1.3	0.4	-0.3	-1.2	-0.9	0.1	-0.8	-0.4	-0.4	0.1	0.8	1.4	-0.5
Medication: Simvastatin	0.6	0.9	2.5	0.3	0.1	0.4	1.6	1.6	1.4	-0.3	0.1	-0.1	1.3	-0.1	-0.8	-1.1	1.2
Fluid intelligence score	0.8	1.6	5.8	-0.1	-0.5	-0.6	1.2	0.8	0.7	-1.2	-2.4	-1.8	1.1	2.2	0.8	0.8	1.3
Illnesses of siblings	0.4	0.6	4.9	-2.2	0.0	-0.0	-0.9	0.6	-0.1	0.1	0.6	0.8	-0.4	0.4	-0.2	-0.9	-0.4
Neuroticism score	0.4	0.8	1.9	-1.3	-1.0	-1.4	0.8	-0.1	1.0	-1.1	-0.3	-1.0	0.8	0.6	0.9	0.7	0.9
Weight	1.3	6.3	11.9	0.5	2.7	2.3	-2.7	-1.3	-2.2	2.9	3.4	3.3	-2.7	-2.7	-1.9	-2.1	-2.6
Impedance of arm (right)	3.6	16.8	29.6	0.3	-4.9	-4.1	4.8	3.7	4.7	-5.0	-3.4	-4.7	5.4	3.6	2.5	3.0	4.3
Arm fat percentage (right)	0.6	2.3	13.3	-0.4	0.6	0.7	-1.0	0.2	0.0	1.3	3.7	2.2	-0.4	-2.0	-1.5	-0.9	-1.6
Trunk fat-free mass	1.1	6.2	11.3	0.4	3.3	2.7	-2.8	-2.2	-3.0	3.0	1.5	2.6	-3.4	-2.2	-1.5	-2.3	-2.2
Hip circumference	1.6	6.8	13.2	-0.3	2.9	2.6	-2.5	-0.9	-1.8	3.2	3.6	3.6	-2.3	-3.0	-2.5	-2.2	-2.8
Time employed in main current job	0.7	0.9	2.2	-1.5	-0.6	-0.8	0.3	-0.3	-0.2	-1.2	-1.0	-1.3	0.3	0.6	1.4	1.4	0.6
Alcohol intake versus 10 years previously	1.8	2.8	8.1	-0.2	2.8	2.2	-0.8	0.1	-0.4	2.1	1.1	2.4	-1.2	-0.7	-2.0	-2.6	-0.9
Father’s age at death	0.7	1.0	3.2	0.1	-1.8	-1.3	0.7	0.5	0.8	-1.7	-0.0	-0.8	0.7	0.3	1.3	0.7	1.3
Worrier / anxious feelings	1.1	2.1	5.3	-0.6	-1.4	-1.9	1.7	1.9	2.3	-1.5	-0.9	-1.1	2.1	0.6	0.3	0.3	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.5	0.4	-0.2	0.5	-1.5	-1.6	-1.4	0.5	-0.4	0.3	-0.9	-0.3	-0.1	0.8	-1.6
Falls in the last year	2.2	3.0	6.0	1.3	-2.4	-2.0	1.8	1.7	1.8	-1.8	-1.4	-1.9	2.0	1.4	1.2	0.9	1.7
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	0.6	-0.4	-0.8	-1.2	-0.5	-0.6	-0.3	0.3	-0.0	-0.7	0.7	0.7	0.8	-0.7
Number of live births	0.7	1.1	3.3	0.3	-1.3	-1.2	0.1	0.2	0.1	-1.5	-1.0	-1.2	0.8	0.8	1.4	1.8	0.3
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	10.3	-1.7	3.2	2.3	-0.8	-0.7	-1.2	2.5	-0.4	1.3	-1.7	-1.0	-1.8	-1.7	-1.2
Pulse rate	0.9	1.6	4.8	-0.4	1.4	0.9	-1.8	-1.4	-2.2	1.3	0.2	0.7	-2.2	-0.1	0.5	0.2	-1.5
Happiness	0.4	0.4	2.7	1.6	-0.7	-0.7	0.0	-0.2	0.3	-1.0	-0.5	-0.4	0.1	-0.2	0.8	0.3	0.6
Noisy workplace	0.7	0.9	4.7	2.2	-0.5	-0.3	0.9	1.1	1.1	0.0	1.0	0.5	0.6	-1.1	-0.4	-0.9	0.6
Qualifications: A levels/AS levels or equivalent	0.6	1.2	3.3	-1.4	-0.1	-0.7	0.3	-0.9	-0.9	-0.6	-1.8	-1.8	-0.1	0.2	1.8	1.8	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.2	0.8	0.2	-0.6	-0.4	-0.9	-0.9	-0.2	-0.9	-0.6	-0.9	0.4	1.5	0.8	0.1
Mouth/teeth dental problems: Dentures	1.1	1.8	5.7	-1.0	-0.4	-1.5	0.5	-0.6	-0.2	-1.5	-2.0	-2.1	0.0	1.1	2.4	1.5	1.3
Asthma	1.5	3.0	5.2	2.3	-1.9	-1.7	1.5	1.9	1.9	-2.3	-0.7	-1.7	2.1	1.7	1.1	0.6	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	4.7	-2.2	1.5	1.5	-0.4	0.1	-0.5	0.9	1.0	0.8	-0.5	0.7	-0.8	-0.7	-0.8
Medication: Cholesterol lowering	0.3	0.4	1.5	0.3	0.9	1.2	0.2	0.4	0.1	0.8	0.4	0.5	-0.3	-0.5	-0.7	-1.2	-0.1
Depression (self-reported)	0.3	0.4	2.0	-0.2	1.4	0.3	-0.3	0.2	-0.5	0.5	0.7	0.3	-0.3	1.4	-0.2	-0.1	-0.4
Medication: Lansoprazole	1.1	1.2	4.3	0.1	-0.2	-0.5	1.6	2.1	1.6	-0.4	0.5	-0.0	1.0	0.7	0.1	-1.4	1.8
Prospective memory result	1.4	1.7	4.3	0.3	-1.4	-1.4	-1.7	-1.8	-1.4	-0.8	0.0	-0.4	-1.2	1.2	2.1	1.9	-0.8
Lung cancer (father)	1.2	1.4	6.0	0.5	-2.4	-0.7	1.1	1.1	1.5	-1.5	0.6	-0.2	1.6	-1.1	0.1	-0.1	1.3
Illnesses of mother	0.6	0.8	2.4	-1.2	0.9	1.3	-0.1	-0.4	-0.1	1.4	-0.3	0.7	-0.3	-0.9	-1.5	-0.7	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	9.9	-1.8	3.2	2.3	-0.9	-1.0	-1.2	2.5	-0.5	1.3	-1.7	-1.1	-1.8	-1.5	-1.3
Pulse wave Arterial Stiffness index	0.5	0.5	2.4	0.2	-0.6	0.6	-0.3	-1.5	-1.2	0.4	-0.3	-0.4	-0.5	-0.5	0.6	1.2	-0.6
Impedance of arm (left)	3.4	15.9	28.6	0.7	-4.7	-3.8	4.9	4.0	4.7	-4.9	-3.3	-4.4	5.3	3.3	2.3	2.5	4.3
Arm fat mass (right)	1.0	3.9	13.6	0.0	1.7	1.6	-1.8	-0.4	-1.0	2.2	3.7	2.9	-1.4	-2.4	-2.0	-1.6	-2.1
Trunk predicted mass	1.1	6.0	11.2	0.4	3.3	2.6	-2.8	-2.2	-3.0	3.0	1.4	2.5	-3.4	-2.1	-1.5	-2.3	-2.1
Standing height	0.1	0.9	3.4	1.8	0.6	0.0	0.8	0.9	0.1	-0.4	-1.5	-0.7	0.2	0.7	0.3	-1.2	1.5
Length of working week for main job	0.3	0.4	0.9	0.7	0.9	0.4	-0.3	-1.0	-0.9	0.9	0.3	0.2	-0.9	-0.1	-0.2	-0.4	-0.2
Exposure to tobacco smoke at home	1.6	1.8	4.5	1.4	1.2	1.3	-0.9	-0.5	-0.6	1.6	2.1	1.9	-0.8	-1.3	-1.5	-1.0	-1.3
Breastfed as a baby	1.1	1.3	5.2	0.2	-0.4	-0.5	-0.1	1.5	0.6	-0.1	2.3	1.6	-0.0	-1.9	-0.1	-1.9	0.6
Tense / ‘highly strung’	0.3	0.5	1.7	-0.6	-0.9	-0.3	0.9	-0.1	1.2	-0.4	-0.3	-0.3	1.3	0.7	-0.7	0.5	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.5	-1.2	1.2	0.9	-0.7	-1.2	-1.2	1.2	-0.1	0.2	-1.0	-0.5	-0.1	0.1	-0.9
Hair/balding pattern: Pattern 4	0.7	1.7	5.2	0.9	1.3	1.6	0.1	0.3	0.3	1.6	1.8	1.9	-0.0	-0.5	-2.3	-1.6	-1.0
Birth weight of first child	1.6	3.0	8.1	0.2	1.3	2.5	-0.7	0.4	-0.3	2.2	1.5	2.8	-0.6	-1.6	-2.7	-2.2	-1.7
Peak expiratory flow (PEF)	1.5	3.5	14.2	-0.9	2.6	2.8	0.3	0.7	0.3	2.9	0.2	1.9	-0.1	-0.6	-3.8	-2.4	-1.3
Pulse wave reflection index	0.4	0.5	2.0	1.2	-1.4	-0.1	0.5	-0.7	0.3	-0.3	-0.3	-0.6	1.0	-0.1	-0.0	1.3	-0.1
Ever highly irritable/argumentative for 2 days	2.3	2.8	7.0	0.3	1.8	1.6	-1.6	-1.0	-1.2	2.1	2.5	2.7	-1.5	-0.9	-1.7	-1.4	-1.9
Loud music exposure frequency	0.8	0.9	2.3	1.5	-0.8	0.1	1.2	1.2	1.5	-0.3	0.4	0.3	1.3	0.4	-0.9	-0.8	0.6
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.2	-0.8	0.3	0.1	1.4	0.6	0.5	-0.8	-1.8	-1.2	0.6	1.8	0.8	0.1	1.5
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	3.6	-0.4	0.3	0.8	1.7	0.8	1.3	0.2	0.5	-0.2	1.9	0.5	-1.9	-0.4	0.3
Blood clot in the leg (DVT)	4.1	5.3	9.4	-1.2	1.8	2.5	-2.4	-2.0	-2.1	3.0	2.5	3.1	-2.5	-2.4	-1.7	-1.0	-2.9
Medication: Paracetamol	1.1	1.8	4.2	-1.4	-0.3	-1.1	1.1	0.6	0.8	-1.4	-1.8	-2.0	1.0	1.8	1.5	1.1	1.4
Headache pain in last month	1.5	2.5	4.3	-1.8	-2.0	-1.5	1.4	1.3	1.6	-2.0	-0.9	-1.8	1.4	1.7	1.3	0.3	2.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.2	0.4	-0.8	-1.1	0.2	0.4	0.3	-0.7	-1.1	-0.7	0.3	0.6	0.8	0.4	0.8
Glaucoma (self-reported)	0.4	0.5	1.4	-0.7	-0.9	-0.7	0.6	0.7	0.4	-1.1	-0.1	-0.8	0.5	-0.0	0.9	-0.1	1.2
Gout (self-reported)	0.3	0.4	1.4	0.5	0.3	-0.3	0.9	0.3	0.0	-0.4	-1.0	-1.2	0.5	0.1	0.6	0.6	0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.8	-0.7	0.2	0.0	0.2	0.6	0.1	0.0	0.4	0.2	-0.1	-1.3	0.1	-0.5	0.3
Medication: Amlodipine	1.5	2.2	5.9	-1.6	2.4	0.8	-1.7	-2.3	-2.1	1.4	0.3	0.3	-2.1	-0.5	0.6	0.4	-1.3
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.7	0.2	-1.3	-1.8	-0.1	0.3	0.0	-1.6	-0.6	-1.4	0.0	1.6	2.2	1.2	0.8
Birth weight	0.4	0.8	3.1	-1.5	1.8	1.4	0.0	-0.8	-0.5	0.7	-0.9	0.0	-0.2	0.4	-0.7	0.5	-0.6
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.9	0.2	-0.1	-0.8	0.8	0.9	0.6	-0.9	-0.2	-0.5	0.5	0.3	0.9	-0.5	1.4
High blood pressure (siblings)	0.1	0.2	0.5	0.5	0.3	0.7	0.3	-0.7	-0.4	0.7	0.0	-0.0	-0.1	-0.4	-0.5	0.4	-0.4
Forced vital capacity (FVC), Best measure	0.2	0.9	4.5	-1.1	2.1	1.2	-0.2	-0.7	-0.7	1.1	-1.2	-0.0	-0.9	-0.3	-0.6	-0.6	-0.2
Body fat percentage	0.5	1.9	11.6	-0.1	0.4	0.4	-0.9	0.5	0.1	1.0	3.4	2.1	-0.2	-2.0	-1.3	-0.9	-1.3
Leg fat percentage (right)	0.4	1.4	8.1	-0.7	0.3	0.1	-1.4	-0.3	-0.3	0.7	2.8	1.7	-0.8	-1.9	-0.4	-0.5	-1.2
Arm fat-free mass (right)	1.8	9.3	16.3	0.7	4.0	3.2	-3.5	-2.3	-3.6	3.8	2.2	3.4	-4.0	-2.6	-1.9	-2.7	-2.9
Exposure to tobacco smoke outside home	0.7	1.0	4.5	-1.1	-0.7	0.2	0.9	1.1	1.2	-0.1	2.1	0.7	1.2	-0.8	-0.8	-0.7	0.5
Comparative body size at age 10	3.0	8.3	17.2	-1.3	3.0	2.6	-3.7	-3.6	-4.0	3.4	1.1	2.5	-4.2	-2.8	-0.7	-0.7	-3.5
Number of full brothers	0.1	0.2	0.9	-0.0	0.1	0.4	-0.3	-0.8	-0.2	0.1	0.9	0.4	-0.4	-0.6	-0.1	0.2	-0.3
Worry too long after embarrassment	0.4	0.6	1.7	-0.3	-0.6	-0.9	1.0	0.7	1.3	-0.9	-0.2	-0.7	0.9	-0.1	0.3	-0.4	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.1	-1.4	1.4	0.7	0.1	0.2	-0.0	0.9	-0.3	0.2	-0.1	0.8	-0.8	-0.3	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	0.9	0.7	-0.9	-0.4	0.2	1.0	0.9	-0.9	0.5	-0.1	0.6	0.4	0.2	-0.2	0.6
Number of children fathered	1.1	1.3	3.6	-1.1	1.5	1.8	-0.6	-1.9	-1.2	1.3	-0.2	0.6	-1.1	-0.7	-0.7	-0.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.5	-1.6	1.2	-0.0	-1.4	-1.5	-1.4	0.7	0.1	0.1	-1.4	-0.6	0.4	0.6	-1.1
Age at first live birth	0.1	0.2	1.0	-0.2	0.4	-0.2	-0.3	-0.2	-0.2	0.7	-0.1	0.4	-0.4	-1.0	-0.4	-0.4	-0.4
Pulse wave peak to peak time	0.5	0.6	2.8	-0.3	0.6	-0.6	0.5	1.7	1.3	-0.4	0.1	0.3	0.5	0.6	-0.5	-1.3	0.8
Health satisfaction	0.4	0.5	1.2	0.9	-0.2	-0.4	0.7	0.8	0.8	-0.7	-1.1	-0.6	0.9	1.1	0.1	0.2	0.7
Shortness of breath walking on level ground	0.6	0.7	1.5	1.2	-0.9	-1.0	0.2	0.8	0.2	-1.0	-0.6	-0.6	0.6	0.9	1.0	0.9	0.5
Qualifications: College or University degree	0.7	2.2	7.5	-0.2	-0.5	-1.1	-0.8	-1.9	-1.9	-1.2	-1.5	-1.8	-1.1	1.1	2.7	2.2	0.2
Eye problems/disorders: None of the above	0.2	0.3	1.6	-0.3	-0.0	-0.4	-0.4	-0.7	0.1	-0.2	0.6	0.4	-0.4	-1.3	0.4	-0.2	0.2
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.7	-0.9	1.9	1.6	0.5	0.3	-0.0	0.8	0.3	0.7	0.0	-0.8	-1.2	-1.6	0.1
Emphysema/chronic bronchitis	5.0	5.7	13.3	1.1	-2.8	-3.6	1.5	1.5	1.5	-3.1	-2.3	-3.1	1.9	2.0	2.9	2.0	2.4
Medication for pain relief, constipation, heartburn	0.5	0.8	6.9	2.6	-1.5	-1.1	-0.2	-0.1	0.3	-0.7	0.4	0.2	0.2	0.2	0.4	0.3	0.3
Neck or shoulder pain in last month	0.5	0.7	1.9	-0.3	-0.7	-1.2	0.6	0.6	0.8	-0.8	-1.4	-1.1	0.7	1.1	0.7	0.9	0.4
Medication: Blood pressure	0.5	0.9	2.9	-1.7	1.3	1.0	-0.7	-1.3	-0.9	0.9	0.7	0.4	-0.8	-0.6	-0.2	0.6	-1.3
Angina (self-reported)	0.3	0.3	1.1	0.7	0.0	0.1	1.1	0.6	0.8	-0.3	-0.7	-0.5	0.8	-0.1	-0.2	-0.2	0.7
Migraine (self-reported)	0.8	0.9	3.0	-0.6	0.1	-0.8	1.1	0.7	0.5	-1.0	-1.7	-1.1	0.5	1.0	1.1	-0.0	1.6
Medication: Ibuprofen	1.7	2.0	5.3	-2.1	2.3	2.3	-0.6	-0.0	-0.6	1.7	1.2	1.5	-0.9	-0.1	-1.5	-1.1	-1.3
Medication: Allopurinol	0.3	0.4	1.7	0.5	0.3	-0.1	1.0	0.7	0.4	-0.3	-1.3	-0.8	0.4	-0.0	0.3	-0.3	1.0
Medication: Omeprazole	0.4	0.4	1.2	-1.1	-0.5	-0.8	-0.8	-0.6	-0.6	-0.4	0.2	-0.5	-0.7	-0.4	1.1	0.5	-0.0
Medication: Seretide 50 evohaler	0.3	0.3	1.1	-0.2	0.4	0.5	-0.5	0.5	-0.6	-0.1	1.1	0.9	-0.7	-0.2	0.3	-1.0	0.1
Mean time to correctly identify matches	0.5	1.0	2.4	1.6	-1.2	-1.1	0.7	-0.1	0.7	-1.2	-0.5	-1.2	0.9	0.9	0.9	1.3	0.5
Heart disease (mother)	0.8	1.0	2.3	0.3	-1.3	-1.1	1.1	0.4	0.4	-1.2	-0.7	-1.4	0.8	0.9	1.2	0.4	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.6	0.7	0.1	-0.4	0.3	1.0	1.0	0.2	0.4	0.7	0.0	-1.0	-0.6	-1.6	0.5
Whole body fat mass	0.8	3.3	12.7	0.5	1.3	1.1	-1.8	-0.2	-0.8	1.8	3.6	2.7	-1.3	-2.5	-1.5	-1.5	-1.9
Leg fat mass (right)	1.0	4.0	13.5	0.0	1.8	1.3	-2.2	-0.7	-1.2	2.1	3.7	2.9	-1.8	-2.4	-1.5	-1.5	-2.1
Arm predicted mass (right)	1.9	9.9	17.7	0.7	4.2	3.4	-3.4	-2.0	-3.4	4.0	2.5	3.7	-3.9	-2.8	-2.2	-3.1	-2.9
Pulse rate, automated reading	0.1	0.2	0.7	0.2	-0.1	0.1	-0.6	0.5	-0.6	0.1	0.8	0.4	-0.7	-0.5	0.4	-0.7	0.2
Alcohol intake frequency.	0.3	0.8	1.7	-0.1	1.2	1.3	-1.0	-0.2	-0.9	1.0	0.1	1.1	-1.2	-0.9	-0.5	-1.1	-0.7
Comparative height size at age 10	0.1	0.7	5.3	2.3	0.4	0.6	0.0	0.1	-0.3	-0.1	-1.2	0.3	-0.4	-0.9	-0.1	-1.2	0.6
Number of full sisters	1.3	1.5	4.7	1.0	-0.6	-0.5	1.7	2.2	1.9	-0.8	0.1	-0.4	1.6	0.2	-0.5	-1.4	1.8
Suffer from ‘nerves’	0.3	0.4	3.7	-1.9	-0.1	-0.5	0.3	-0.4	0.1	0.1	0.9	-0.4	0.2	0.1	0.2	0.6	-0.2
Overall health rating	0.2	0.4	1.1	0.7	-1.0	-0.8	0.1	0.5	0.5	-0.9	-0.6	-0.4	0.7	0.6	0.3	0.2	0.4
Chest pain or discomfort	0.8	1.2	3.2	-0.9	-0.2	-1.0	1.0	0.6	0.7	-1.3	-1.0	-1.6	0.8	1.8	1.2	0.6	1.5
Had major operations	0.7	0.8	3.3	-0.4	1.2	0.9	-0.2	-0.0	-0.4	1.0	-0.2	0.9	-0.8	-1.6	-0.7	-1.8	0.1
Age at last live birth	0.5	0.7	1.9	-0.0	-0.7	-1.3	0.9	1.2	1.4	-0.8	0.7	-0.3	0.9	-0.5	0.3	-0.3	1.2
Family relationship satisfaction	0.1	0.2	1.2	0.7	-0.0	-0.4	-0.1	-0.2	0.2	-0.2	-1.1	-0.4	-0.0	0.3	0.3	0.3	-0.0
Leg pain on walking	0.3	0.4	2.2	1.3	-0.1	0.1	-0.1	0.3	-0.1	-0.5	-1.5	-0.4	0.2	1.1	0.1	0.5	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.8	0.9	-0.4	-0.9	0.4	0.3	0.3	-0.5	-0.5	-0.7	0.3	0.6	0.7	0.3	0.7
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.9	1.7	0.8	1.7	-1.3	-0.5	-1.2	1.1	0.7	1.3	-1.0	-0.9	-1.1	-0.4	-1.6
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	4.8	-2.2	1.2	1.7	-1.8	-2.2	-1.9	1.3	-0.2	0.9	-1.8	-1.0	-0.6	0.3	-1.9
Medication: Aspirin	0.3	0.4	1.6	-0.2	1.1	1.3	0.8	0.5	0.1	0.5	-0.0	0.0	0.4	-0.2	-0.8	-0.6	0.1
Supplements: Vitamin C	1.2	1.4	5.7	-0.1	-1.2	-0.5	1.4	2.4	1.5	-0.8	0.6	0.3	1.3	-0.8	0.0	-1.5	1.6
Knee pain experienced in last month	1.0	1.5	4.4	0.2	-0.6	-1.1	-0.7	-0.7	-1.0	-1.1	-1.7	-1.6	-0.2	1.4	2.0	2.1	-0.1
Hypertension (Self-reported)	0.4	1.0	2.2	-1.5	1.4	1.2	-0.4	-1.3	-0.7	0.9	1.4	0.9	-0.7	-0.8	-0.8	-0.1	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	-0.0	0.4	-0.2	1.0	1.1	0.7	-0.0	-0.0	-0.6	0.4	0.6	0.1	-0.7	1.0
Illnesses of father: Heart disease	0.9	1.2	3.3	0.7	-0.5	-0.6	1.5	1.0	0.7	-0.9	-1.8	-1.8	1.2	1.1	0.8	0.6	1.4
Illnesses of siblings: Diabetes	0.2	0.2	0.7	0.5	0.7	0.3	0.3	-0.4	0.1	0.7	0.2	0.4	-0.1	-0.8	-0.5	-0.0	-0.2
Smoking status: Previous	0.4	0.6	1.8	0.2	-0.5	-0.2	1.0	0.2	0.8	-0.7	-0.8	-1.0	0.9	1.3	0.2	0.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.6	1.9	0.6	-0.1	1.2	1.4	1.0	-0.4	-1.5	-0.6	0.9	1.3	-0.1	-0.3	1.0
Whole body fat-free mass	1.4	8.0	14.8	0.5	3.9	3.0	-3.2	-2.2	-3.2	3.6	2.1	3.1	-3.7	-2.3	-1.9	-2.4	-2.7
Leg fat-free mass (right)	1.8	9.7	17.6	0.7	4.2	3.3	-3.4	-2.3	-3.5	4.1	2.7	3.5	-3.9	-2.2	-2.3	-2.3	-3.4
Arm fat percentage (left)	0.7	2.7	13.7	-0.3	0.9	0.9	-1.4	0.1	-0.3	1.5	3.7	2.4	-0.7	-2.1	-1.6	-1.0	-1.8
Average weekly red wine intake	0.2	0.3	1.3	-0.4	-1.1	-0.5	0.5	0.5	0.2	-0.4	-0.5	-0.9	0.7	0.6	0.3	0.6	0.2
Handedness (chirality/laterality): Left-handed	1.9	2.3	5.0	0.4	-1.9	-1.9	0.5	-0.2	-0.2	-1.9	-2.0	-2.2	0.7	0.9	2.2	1.9	1.2
Mood swings	0.1	0.3	0.7	-0.4	-0.2	-0.5	0.4	-0.3	0.7	-0.6	0.7	0.0	0.2	0.6	0.3	-0.6	0.8
Loneliness, isolation	0.7	1.0	3.2	0.0	-0.9	-1.4	0.3	0.1	0.6	-1.3	-0.3	-1.2	0.7	1.8	1.2	1.2	0.6
Long-standing illness, disability or infirmity	2.0	3.0	6.1	0.9	-2.0	-2.5	0.8	1.0	0.8	-2.4	-1.2	-2.4	1.4	1.9	2.1	2.2	1.2
Ever had bowel cancer screening	0.7	0.9	3.1	-0.5	-1.5	-1.8	0.2	-0.5	0.1	-0.8	-0.3	-1.1	0.5	-0.9	1.0	1.4	0.4
Diabetes diagnosed by doctor	0.1	0.2	1.6	-0.5	-0.2	-0.5	0.4	0.5	0.5	-0.2	1.3	-0.2	0.3	0.1	0.3	0.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	4.8	-0.0	-1.9	-2.2	0.9	0.4	1.1	-2.1	0.0	-1.7	1.2	1.6	1.8	1.4	1.6
Friendships satisfaction	0.1	0.1	0.3	0.4	-0.3	-0.5	-0.2	0.3	0.2	-0.5	-0.1	-0.2	0.0	-0.2	0.4	0.1	0.2
Qualifications: nursing, teaching	0.2	0.3	1.1	-0.1	-0.1	-0.5	-0.2	-0.6	-0.5	-0.3	-0.5	-0.6	-0.1	-0.3	0.8	1.1	-0.3
Commuting to job workplace: Walk	1.1	1.2	3.3	-0.1	-0.6	-1.1	1.2	-0.1	0.7	-1.0	-1.6	-1.8	1.1	1.0	1.1	1.6	0.8
Eye problems/disorders: Cataract	0.4	0.5	3.6	1.9	-0.4	0.0	0.2	0.4	0.1	-0.0	0.3	-0.1	0.7	1.4	-0.4	0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.2	1.4	0.6	0.2	1.3	-0.2	0.7	-0.2	-2.0	-1.1	0.9	2.0	-0.2	0.9	0.5
Medication for cholesterol	0.3	0.4	1.6	0.8	-1.3	-0.9	-0.0	0.1	0.1	-0.7	-0.1	-0.7	0.1	0.1	1.0	0.5	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	5.5	1.2	-1.4	-1.9	2.1	1.9	2.3	-1.6	-0.9	-1.5	2.1	0.9	0.5	-0.0	2.1
Back pain experienced in last month	0.6	0.9	2.5	-1.1	0.5	0.0	-1.5	-1.3	-1.6	0.2	-0.5	-0.2	-1.5	0.6	1.1	0.8	-0.8
Mineral and other dietary supplements	0.2	0.3	0.9	-0.2	0.5	0.5	0.7	0.6	0.5	-0.1	-0.9	-0.4	0.7	0.5	-0.5	-0.2	0.6
Breast cancer (self-reported)	0.4	0.5	1.6	1.3	0.1	0.6	-1.0	-0.4	-0.9	0.3	-0.2	0.4	-0.5	-0.3	-0.4	0.5	-1.3
Asthma (self-reported)	1.3	2.5	4.3	2.0	-1.5	-1.5	1.5	1.8	1.7	-2.1	-0.8	-1.7	1.9	1.7	1.1	0.5	1.8
Osteoporosis (self-reported)	0.7	0.9	2.9	0.5	-1.3	-1.0	1.0	1.7	1.2	-0.7	-0.4	-0.5	1.1	0.4	-0.0	-0.8	1.3
Osteoarthritis (self-reported)	0.4	0.5	1.9	-1.1	-0.4	-0.0	-0.6	-0.8	-0.7	-0.2	-1.4	-0.4	-0.6	1.0	0.8	0.3	-0.2
Medication: Aspirin	0.4	0.5	1.6	-0.5	1.0	1.1	1.3	0.7	0.6	0.1	-0.4	-0.3	0.8	0.1	-0.6	-0.5	0.6
Medication: Gliclazide	0.3	0.4	1.1	0.1	-0.7	-0.5	0.8	0.8	1.0	-0.7	0.2	-0.4	0.9	0.2	0.0	-0.1	0.9
Illnesses of father: None of the above (group 1)	0.3	0.4	1.8	-0.4	0.3	0.2	-0.9	-0.6	-0.8	0.3	-0.6	0.3	-0.7	-1.4	0.0	0.1	-0.8
Smoking status: Current	0.3	0.4	1.4	-0.0	-0.4	-0.6	0.8	1.2	1.1	-0.5	0.7	0.3	0.6	0.3	0.1	-0.7	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.7	8.6	-0.8	2.4	2.9	-1.6	-1.4	-1.8	2.5	0.7	2.0	-1.6	-2.2	-2.1	-1.0	-2.3
Whole body water mass	1.5	8.8	16.0	0.5	4.0	3.2	-3.3	-2.2	-3.3	3.8	2.3	3.3	-3.8	-2.4	-2.1	-2.7	-2.9
Leg predicted mass (right)	1.8	9.6	17.0	0.7	4.1	3.3	-3.4	-2.3	-3.5	4.0	2.6	3.5	-3.8	-2.3	-2.3	-2.2	-3.4
Arm fat mass (left)	1.2	4.9	15.3	-0.0	1.9	1.8	-2.1	-0.5	-1.0	2.5	3.9	3.2	-1.6	-2.6	-2.3	-2.0	-2.3
Number of self-reported non-cancer illnesses	0.5	0.9	4.0	-0.5	-0.1	-0.1	0.6	-0.4	0.2	-0.9	-2.0	-1.6	0.4	1.4	0.8	0.9	0.8
Average weekly champagne plus white wine intake	1.1	1.5	5.9	0.3	-0.2	1.3	0.5	0.8	1.0	1.1	1.3	1.5	0.7	-1.6	-2.4	-1.5	-0.6
Miserableness	0.8	1.4	3.7	-1.9	-0.9	-0.9	0.1	-1.5	-0.2	-1.1	-0.9	-1.8	-0.1	0.8	1.8	1.8	0.4
Guilty feelings	0.3	0.5	2.5	0.4	-0.9	-1.1	0.1	0.4	0.8	-0.4	1.6	0.3	0.4	-0.5	0.1	-0.2	0.4
Wears glasses or contact lenses	1.1	1.3	4.3	-0.8	-0.1	0.1	2.1	1.1	1.5	-0.7	-0.6	-1.4	1.6	1.6	-0.1	0.2	1.3
Ever taken oral contraceptive pill	2.5	2.8	8.7	0.0	-1.1	-1.4	2.1	3.0	2.7	-1.5	-0.1	-0.8	2.3	1.6	0.1	-0.6	2.2
Hearing aid user	2.5	2.8	8.9	0.2	-2.2	-3.0	-0.2	-0.2	-0.1	-2.2	-0.8	-1.8	0.5	0.8	2.9	2.8	0.6
Mother’s age at death	0.3	0.4	1.7	0.1	-0.1	-0.4	0.1	1.1	0.5	-0.0	1.3	0.7	-0.1	-0.2	0.1	-1.1	0.6
Financial situation satisfaction	0.4	0.4	3.8	1.9	-0.6	-0.0	-0.2	0.3	0.3	-0.3	-0.6	0.0	-0.0	1.1	0.2	-0.2	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.1	-1.1	-0.3	0.1	-0.0	-0.3	-0.0	0.1	0.9	0.3	0.0	-0.2	0.1	0.5	-0.5
Commuting to job workplace: Public transport	0.9	1.1	4.7	-0.9	-1.3	-2.2	0.2	0.7	0.3	-1.1	0.5	-0.7	0.4	1.3	1.5	0.1	1.0
Eye problems/disorders: Glaucoma	1.0	1.2	3.2	-0.8	-1.0	-0.9	1.4	1.6	1.1	-1.3	-0.3	-1.1	1.2	0.4	0.8	-0.3	1.8
Medication: Blood pressure	0.1	0.3	1.2	-0.1	0.7	0.1	-0.2	-1.1	-0.6	-0.4	-0.4	-0.4	-0.4	0.7	0.6	0.8	0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	0.8	0.2	0.0	1.1	0.4	0.6	-0.3	-0.6	-1.0	0.6	-0.3	0.5	-0.2	1.2
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.9	-0.1	-0.7	0.0	-0.9	-0.5	-0.3	0.7	1.4	1.2	-0.6	-1.7	-0.3	-0.2	-1.0
High cholesterol (Self-reported)	0.5	0.9	3.1	0.7	0.3	1.1	0.6	0.8	0.9	0.8	1.0	1.2	0.6	-0.8	-1.8	-1.4	-0.2
Medication: Bendroflumethiazide	0.5	0.7	4.7	0.0	0.3	0.7	-0.7	-0.5	-0.4	0.3	2.2	1.0	-0.4	-1.5	-0.5	-0.3	-0.6
Medication: Paracetamol	1.1	1.7	3.3	-1.3	-0.1	-0.9	1.4	0.8	1.1	-1.4	-1.8	-1.8	1.2	1.8	1.3	0.9	1.5
Medication: Lisinopril	0.6	0.8	3.0	-0.6	1.7	1.0	0.5	0.1	0.7	0.8	0.3	1.1	-0.3	-0.3	-1.1	-1.6	0.3
Medication: Atorvastatin	0.7	0.8	2.7	0.9	1.7	1.6	-0.2	-0.5	-0.5	1.2	-0.7	0.3	-0.5	-0.8	-1.1	-0.7	-0.6
Illnesses of father: High blood pressure	1.4	1.7	5.5	-0.6	0.0	0.1	2.1	1.6	1.5	-0.8	-1.2	-1.0	1.6	2.4	-0.3	-0.1	1.6
Alcohol drinker status: Never	0.2	0.2	1.1	1.1	-0.5	-0.4	-0.2	0.7	0.1	-0.1	-0.1	0.2	0.3	-0.8	-0.2	-0.2	-0.1
Ever smoked	1.3	2.3	4.4	-0.0	-1.1	-1.4	1.9	0.6	1.4	-1.8	-1.8	-2.1	1.5	1.9	1.3	0.9	2.0
Basal metabolic rate	1.4	7.8	13.4	0.6	3.7	2.9	-3.1	-2.0	-3.0	3.5	2.5	3.2	-3.5	-2.4	-2.0	-2.4	-2.8
Leg fat percentage (left)	0.5	2.0	9.8	-0.6	0.6	0.3	-1.6	-0.2	-0.5	1.0	3.1	2.0	-1.0	-2.3	-0.6	-0.8	-1.4
Arm fat-free mass (left)	1.6	8.3	14.2	0.7	3.8	3.0	-3.2	-1.9	-3.1	3.5	2.5	3.4	-3.6	-2.6	-2.0	-2.8	-2.6
Number of operations (self-reported)	0.4	0.6	2.6	-1.2	0.2	0.5	1.1	-0.0	0.7	-0.1	-1.6	-0.5	0.6	-0.0	-0.4	-0.8	1.1
Average weekly beer plus cider intake	0.7	1.0	3.2	-0.4	1.8	1.1	-0.1	0.8	0.0	0.8	1.3	1.1	-0.4	-0.7	-1.0	-1.8	-0.0
Irritability	0.4	0.7	2.4	-1.2	1.3	1.1	-0.5	-1.5	-0.9	0.3	-0.7	-0.1	-1.0	-0.0	0.3	0.2	-0.4
Risk taking	0.2	0.2	0.6	-0.4	0.4	0.6	0.7	0.3	0.4	0.3	0.2	0.3	0.3	-0.8	-0.6	-0.7	0.4
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.4	0.3	-0.9	-0.5	-0.9	-1.6	-0.5	-0.2	1.0	0.3	-0.6	-1.1	0.2	0.9	-0.7
Fractured/broken bones in last 5 years	1.3	1.7	3.1	-1.2	-1.6	-1.8	1.1	1.6	1.6	-1.6	0.2	-0.7	1.1	1.2	1.0	-0.5	1.7
Age started oral contraceptive pill	0.6	0.7	2.1	-0.6	0.6	1.0	-1.0	-1.1	-1.4	0.3	-1.2	-0.5	-0.9	0.3	0.5	0.7	-0.7
Diastolic blood pressure, automated reading	1.0	3.0	7.8	-1.2	2.3	1.6	0.2	1.4	0.6	1.8	2.4	2.4	-0.1	-1.5	-2.3	-2.8	-0.4
Ever depressed for a whole week	0.2	0.3	1.9	0.4	-0.2	-0.4	-0.5	-0.2	-0.2	-0.2	1.4	0.6	-0.3	0.6	0.3	0.5	-0.5
Unable to work because of sickness or disability	1.3	1.6	4.9	-0.5	0.0	-1.3	-0.4	-1.3	-0.7	-0.7	-2.2	-1.6	-0.2	1.8	1.7	2.2	-0.2
Commuting to job workplace: Cycle	0.5	0.6	1.8	-0.2	-0.4	-0.8	1.2	1.2	1.2	-0.4	-0.4	-0.7	1.4	0.6	-0.4	0.1	0.7
Myopia	0.3	0.4	1.2	-0.2	0.4	0.6	0.9	0.6	1.0	0.6	0.8	0.4	0.6	-0.2	-1.1	-0.8	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.5	1.2	-1.1	-0.6	0.3	0.9	0.5	-0.4	-0.7	-0.4	0.6	0.7	0.2	0.1	0.4
Cholesterol lowering medication	0.1	0.2	0.9	0.9	0.2	0.4	0.1	0.2	0.2	0.3	0.0	0.5	0.3	-0.2	-0.7	-0.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.3	-1.1	-1.1	-1.5	-0.2	-0.1	-0.0	-0.9	-0.1	-0.9	-0.1	-0.3	1.5	0.6	0.6
Pain experienced in last month	1.3	2.1	5.0	1.2	1.6	1.8	-0.1	-0.1	-0.2	1.6	1.4	2.1	-0.5	-2.2	-2.1	-1.8	-0.7
Supplements: Calcium	0.2	0.2	0.7	0.0	-0.6	0.4	0.2	0.2	0.2	0.3	0.5	0.4	0.5	-0.8	-0.9	-0.5	-0.3
Basal cell carcinoma (self-reported)	1.1	1.3	4.0	-1.0	0.6	0.6	-1.5	-1.7	-2.0	0.8	0.4	0.0	-2.0	-0.3	1.0	0.3	-1.0
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	-0.3	1.2	0.4	-0.7	-0.5	-1.2	0.6	-0.9	0.0	-1.3	-0.1	0.7	-0.2	-0.3
Deep venous thrombosis (DVT) (self-reported)	3.2	4.1	8.4	-0.7	1.4	2.3	-1.9	-1.5	-1.6	2.7	2.4	2.9	-2.0	-2.3	-1.8	-1.1	-2.5
Heart disease (siblings)	3.1	3.8	7.3	2.3	-2.3	-1.8	1.9	0.2	0.8	-2.3	-2.5	-2.7	1.4	-0.2	2.3	1.4	2.5
Alcohol drinker status: Previous	0.2	0.2	1.1	0.1	0.3	0.2	-0.2	0.4	0.1	0.1	0.5	0.4	-0.5	-1.1	0.3	-0.7	0.1
Pack years of smoking	0.9	1.4	4.2	-0.5	0.9	0.5	-1.5	-1.4	-1.0	1.0	2.0	1.6	-1.5	-0.7	-0.1	0.1	-1.5
Impedance of whole body	3.5	17.9	31.6	0.4	-4.8	-4.2	5.2	4.4	5.0	-5.2	-3.5	-4.6	5.6	3.2	2.6	2.4	4.9
Leg fat mass (left)	1.2	4.7	15.4	0.2	1.9	1.5	-2.3	-0.6	-1.4	2.3	3.9	3.1	-2.0	-2.7	-1.7	-1.8	-2.2
Arm predicted mass (left)	1.6	7.9	12.8	0.4	3.6	2.9	-3.2	-1.9	-3.0	3.5	2.5	3.4	-3.5	-2.6	-2.0	-2.7	-2.7