Hub : Genes

ARHGAP22

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1950 0.0480 2.2e-07 0.030 0.088 0.114 0.114 0.107 1.2e-04 8.4e-11 1.1e-13 1.0e-13 6.1e-13
2 GTEx Artery Aorta 0.1800 0.0610 2.6e-03 0.165 NA 0.151 NA 0.164 2.1e-09 NA 1.1e-08 NA 2.4e-09
3 GTEx Artery Tibial 0.2485 0.0535 8.1e-06 0.208 NA 0.197 NA 0.118 3.3e-16 NA 2.2e-15 NA 1.6e-09
4 GTEx Colon Sigmoid 0.2460 0.0730 7.0e-04 0.017 NA 0.031 NA 0.022 8.2e-02 NA 2.9e-02 NA 5.6e-02
5 GTEx Colon Transverse 0.1920 0.0640 2.3e-03 -0.001 NA 0.041 NA 0.007 3.6e-01 NA 4.8e-03 NA 1.4e-01
6 GTEx Pancreas 0.2080 0.0830 6.1e-03 -0.005 NA 0.002 NA -0.002 5.8e-01 NA 2.6e-01 NA 4.2e-01
7 GTEx Whole Blood 0.1240 0.0470 5.3e-03 0.089 NA 0.106 NA 0.083 1.5e-08 NA 5.8e-10 NA 4.3e-08
8 METSIM Adipose 0.1504 0.0425 9.9e-06 0.065 0.060 0.085 0.075 0.072 5.7e-10 2.7e-09 9.4e-13 2.1e-11 6.2e-11
9 NTR Blood 0.0241 0.0097 1.1e-03 0.011 0.012 0.016 0.013 0.017 1.2e-04 5.8e-05 4.0e-06 3.2e-05 2.2e-06
10 YFS Blood 0.2742 0.0410 0.0e+00 0.071 0.125 0.151 0.158 0.138 4.3e-22 1.0e-38 4.2e-47 2.7e-49 1.1e-42
11 TCGA Breast Invasive Carcinoma 0.1308 0.0288 2.3e-15 0.098 0.095 0.103 NA 0.097 1.7e-19 9.2e-19 2.4e-20 NA 3.4e-19
12 TCGA Kidney Renal Papillary Cell Carcinoma 0.1770 0.0610 1.4e-03 0.069 0.071 0.088 NA 0.129 8.6e-05 6.8e-05 9.7e-06 NA 8.0e-08
13 TCGA Brain Lower Grade Glioma 0.1145 0.0373 3.2e-06 0.032 0.043 0.052 NA 0.048 1.3e-04 1.0e-05 1.5e-06 NA 3.3e-06
14 TCGA Lung Adenocarcinoma 0.1048 0.0344 1.8e-05 0.053 0.027 0.054 NA 0.052 7.3e-07 3.9e-04 6.1e-07 NA 1.1e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.7 1.2 5.1 -2.1 -0.8 -0.6 -0.6 -0.2 0.5 1.5 0.7 -0.4 0.8 -0.7 0.8 -2.3 -0.5
Bipolar Disorder or Schizophrenia 0.2 0.4 1.4 -0.4 -0.4 -0.3 -0.9 1.1 -0.2 0.9 0.1 -0.9 -0.2 -0.3 0.4 -1.2 -0.1
Depressed Affect (Nagel 2018) 1.0 2.1 4.1 1.8 1.6 1.6 0.0 -1.2 2.0 -1.6 -1.0 -0.5 -1.4 1.9 1.4 1.7 1.4
Depression (Nagel 2018) 0.2 0.4 0.7 -0.9 0.5 0.4 0.2 -0.5 0.4 -0.8 -0.5 -0.7 -0.6 0.4 0.8 -0.8 -0.6
Intelligence (Savage-Jansen 2018) 0.3 1.0 2.7 1.3 -0.6 -0.4 -0.5 1.7 -0.7 1.6 1.5 1.2 1.1 -0.3 0.7 0.4 0.5
Neuroticism (Nagel 2018) 0.5 1.1 2.5 1.6 0.9 1.0 -0.3 -0.8 1.4 -1.5 -0.8 -0.5 -1.4 1.0 1.0 1.2 0.8
Schizophrenia (2018) 0.2 0.5 2.5 1.2 0.1 0.1 -0.7 1.6 -0.7 0.0 -0.4 -0.8 -0.9 0.1 -0.2 0.4 0.3
Schizophrenia vs Biploar Disorder 0.3 0.3 1.0 0.9 -0.1 -0.1 -0.2 -0.9 -0.2 -1.0 -0.4 -0.4 -0.8 -0.1 -0.2 0.9 -0.1
Worry (Nagel 2018) 0.4 0.7 3.2 1.2 0.3 0.4 -1.5 -0.0 0.6 -1.5 -0.6 0.0 -1.8 0.3 -0.1 0.5 0.1
Alzheimer’s Disease (in mother) 1.4 1.7 4.0 1.3 1.4 1.7 0.5 0.7 0.7 -2.0 -0.8 0.0 -1.6 1.7 0.8 1.1 2.0
Alzheimer’s Disease (in father) 0.6 0.7 3.2 0.8 0.6 0.6 0.6 1.3 1.8 0.2 -0.2 -0.2 -0.1 0.9 0.8 0.4 1.0
Alzheimer’s Disease (including proxy) 2.3 3.3 7.7 2.0 2.1 2.3 0.4 1.3 1.6 -2.0 -1.5 -0.4 -1.7 2.5 1.6 1.5 2.8
Crohns Disease (2017) 1.5 3.2 13.1 3.6 1.2 1.1 2.0 2.1 2.3 0.1 -1.2 0.1 -0.6 1.5 0.6 2.7 1.9
Irritable Bowel Disease (IBD) 0.9 2.1 7.5 2.7 0.2 0.2 2.6 2.1 1.9 0.6 -0.8 -0.6 -0.9 0.5 -0.6 1.6 1.1
Ulcerative Colitis (UC) 0.6 1.2 4.4 0.8 -1.3 -1.3 2.0 1.2 0.3 1.2 0.2 -0.5 -0.2 -1.0 -2.1 0.2 -0.4
Major Depression (MDD) 0.7 0.9 3.8 -1.5 0.1 -0.1 -0.3 0.2 -0.1 -0.3 -0.9 -1.5 -0.8 -0.3 0.8 -2.0 -1.1
Reaction Time 0.9 1.8 6.2 0.5 -0.2 -0.1 1.0 0.1 0.3 1.4 1.7 2.5 2.4 0.0 0.8 2.3 0.6
Verbal and Numeric Reasoning (VNR) 0.6 1.5 6.6 0.8 1.3 1.4 -0.2 2.6 -0.5 0.4 -0.1 0.6 0.5 1.3 1.7 -0.3 1.9
Breast Cancer 0.6 1.4 6.8 1.4 1.0 1.1 0.6 2.6 -0.6 -0.0 -0.6 0.2 0.2 1.3 -1.1 1.4 1.6
Ovarian Cancer 1.1 1.4 4.8 -0.2 -1.9 -1.8 0.3 -0.3 -1.1 1.0 1.1 0.1 -0.5 -1.8 -2.2 -0.1 -1.1
Prostate Cancer 0.2 0.3 0.8 0.3 0.3 0.2 -0.6 -0.1 -0.9 -0.4 -0.8 -0.5 0.8 0.0 0.5 0.6 0.3
Age at First Birth 1.1 1.6 5.0 -0.3 1.2 1.4 0.5 -2.2 0.9 -1.1 -0.2 -1.3 -0.5 1.4 1.7 -0.9 1.9
Bipolar Disorder (2011) 1.1 1.1 5.3 -0.3 -1.2 -1.2 -0.7 -0.0 0.3 2.3 1.2 0.9 1.5 -1.2 0.0 0.0 -0.6
Body Mass Index (BMI) (2010) 0.4 0.6 3.0 -0.7 -0.1 -0.1 -1.7 -0.9 -1.3 0.3 0.0 -0.7 -0.4 -0.4 -0.3 -0.6 -0.8
Coronary Artery Disease (CAD) 4.6 5.4 13.1 -0.8 -3.2 -3.0 1.3 1.2 -1.2 2.2 3.6 2.8 1.7 -3.0 -2.8 -0.1 -2.5
Crohns Disease (2012) 2.4 3.9 10.8 3.3 2.1 2.0 1.2 0.7 2.5 -2.2 -2.2 -1.0 -2.2 2.2 1.0 1.2 1.9
Mean Putamen Volume 1.6 1.8 8.7 -1.0 -0.1 -0.3 -3.0 -1.8 -0.1 -1.3 -1.4 -2.1 -0.9 -0.5 -0.4 -1.8 -0.5
Fasting Glucose 1.0 1.2 2.5 0.7 1.3 1.4 1.2 0.0 1.2 -0.4 -0.3 -0.5 -1.1 1.6 1.6 -0.1 1.5
HbA1C 0.9 1.1 4.0 0.1 0.8 1.0 0.0 -1.1 -1.1 -1.2 -0.6 -1.9 -2.0 0.8 0.0 -0.1 0.7
HDL Cholesterol 0.2 0.4 1.9 -1.4 -0.3 -0.4 -0.2 0.7 -0.1 0.7 -0.5 0.4 0.2 -0.5 -1.1 -0.2 -0.2
LDL Cholesterol 1.7 2.6 5.2 1.1 2.1 2.0 -0.5 0.4 0.3 -1.5 -2.3 -2.0 -2.2 1.9 2.2 1.0 0.9
Lupus 0.2 0.3 2.1 0.7 0.2 0.2 -0.3 -1.5 0.4 -0.4 -0.1 0.3 0.2 0.4 -0.5 -0.2 0.0
Neuroticism (2016) 0.8 1.2 6.9 1.7 0.9 0.6 0.6 0.2 2.6 0.1 -0.1 -0.0 -0.1 0.8 2.1 0.4 0.6
Primary Biliary Cirrhosis 1.5 2.2 5.5 1.6 1.7 1.6 0.7 -0.6 1.0 -1.2 -2.0 -2.3 -1.9 1.7 0.9 -0.2 1.8
Rheumatoid Arthritis 1.7 2.3 5.8 2.0 1.6 1.5 -0.9 -0.9 1.9 -2.4 -1.6 -0.2 -2.0 1.4 1.0 0.8 1.7
Schizophrenia (2014) 0.2 0.4 1.7 0.9 0.4 0.3 -0.5 1.2 -0.2 -0.2 -0.7 -0.9 -1.3 0.4 0.2 0.1 0.1
Triglycerides 1.5 2.4 6.5 1.3 2.3 2.1 0.6 -0.3 1.7 -1.9 -1.1 -0.4 -1.0 2.0 2.5 1.4 1.2
Type 2 Diabetes (T2D) (2012) 1.6 1.8 3.7 1.0 1.7 1.8 0.9 0.1 1.9 -1.5 -1.0 -0.6 -1.1 1.7 1.8 0.7 1.5
Ulcerative Colitis 0.6 0.9 3.3 1.8 -0.5 -0.4 1.5 0.9 1.6 0.2 0.3 -0.1 -0.7 -0.2 -1.2 0.9 -0.0
Blood Eosinophil Count 0.4 3.2 6.0 0.9 2.3 2.3 -2.1 1.0 -2.2 -2.1 -1.2 -1.8 -0.6 2.4 2.4 -0.2 1.5
Blood Platelet Count 0.9 9.9 66.3 -2.8 -1.1 -1.2 -8.1 -1.2 -6.5 0.1 0.3 0.4 1.3 -1.6 -0.0 -2.5 -2.6
Blood Red Count 0.3 3.3 15.0 -2.2 0.1 0.3 -2.3 -1.4 -0.1 -2.0 -0.5 -3.0 -2.3 0.0 -0.5 -3.9 -0.6
Blood White Count 1.0 7.4 46.6 -2.1 1.5 1.2 -6.8 0.5 -4.3 -3.3 -2.2 -1.7 -1.6 0.8 1.0 -2.7 -0.8
Heel T-Score 0.4 3.5 13.0 -2.0 -1.5 -1.4 -3.6 0.1 -3.0 0.1 0.6 -0.7 -0.7 -1.5 -1.7 -2.8 -2.1
BMI 0.1 0.6 2.2 -0.3 -0.3 -0.6 -1.5 -0.5 1.0 -0.6 -0.4 -0.8 -0.4 -0.6 0.2 -0.8 -1.3
Height 0.1 2.0 8.5 -1.0 -0.6 -0.8 -1.4 0.8 -1.6 -0.7 1.8 2.6 2.9 -0.4 1.0 -0.0 -0.8
Waist Hip Ratio (WHR) 0.4 1.7 4.5 -1.1 1.2 1.2 -2.1 -1.0 -1.8 -2.1 -1.1 -1.3 -0.7 1.1 0.7 -0.8 0.9
Systolic Blood Pressure 1.0 5.3 18.7 -3.1 -1.4 -1.7 -4.3 -1.9 -2.6 -0.7 0.0 -0.7 0.0 -2.0 -0.8 -4.0 -2.9
Smoking Status 0.2 0.4 1.6 0.3 0.5 0.3 -1.2 -0.4 0.4 -0.6 -1.2 0.4 -0.5 0.3 -0.7 0.2 0.4
Allergy or Eczema 1.8 4.8 13.7 2.5 2.6 2.6 1.8 1.4 2.2 -0.7 -1.4 0.2 -0.5 2.5 3.7 2.9 2.7
Cardiovascular Disease 0.4 1.4 7.5 -1.0 -0.7 -0.7 -2.3 1.0 -1.3 -0.3 1.3 0.3 0.1 -0.7 0.0 -2.7 -0.3
Hypothyroidism (self reported) 0.6 1.4 4.9 -1.5 -1.1 -1.2 0.8 -2.2 0.4 1.2 0.6 1.3 1.4 -1.3 -0.7 -0.3 -1.0
Respiratory disease 0.2 0.5 2.5 0.6 0.3 0.0 0.4 -0.7 1.4 0.2 -0.5 0.5 0.5 0.0 1.1 1.6 -0.2
Type 2 Diabetes (T2D) (2018) 1.0 1.8 5.8 -1.3 0.6 0.7 -2.4 -1.4 -1.6 -2.0 -0.3 -0.8 -0.6 0.6 1.6 -2.0 0.4
Lung FEV1/FVC ratio 0.1 0.4 2.4 0.1 -0.4 -0.3 -0.4 1.6 0.8 0.1 -0.1 -0.1 -1.3 -0.5 -0.4 -0.1 -0.6
Lung FVC 0.2 1.2 3.1 -0.8 1.2 1.0 -0.9 -1.7 1.0 -0.3 -1.2 -1.6 -0.5 0.9 0.6 -1.8 0.3
Neuroticism 0.3 0.8 2.7 1.6 0.4 0.7 -0.5 -0.1 0.3 -1.3 0.5 0.5 -1.0 0.8 0.8 1.3 0.9
Chronotype (morning person) 0.1 0.3 1.1 -0.5 -0.4 -0.4 0.7 0.5 0.5 1.0 0.3 0.4 0.9 -0.4 0.2 0.5 -0.6
Hair Pigment 0.0 0.9 2.5 0.6 1.0 0.8 -0.2 -0.5 0.5 -1.6 -1.5 -1.2 -1.5 0.6 0.9 0.2 0.3
Tanning 0.1 0.7 1.8 -0.0 1.1 1.0 -1.1 0.7 0.9 -0.4 -1.3 -1.3 -0.6 1.0 -0.1 -1.0 0.2
Hand grip strength (left) 0.1 0.3 1.2 -0.6 -0.3 -0.4 0.2 -0.1 0.6 -0.5 -0.1 -0.6 -0.6 -0.3 -0.7 -1.1 -0.3
Number of treatments/medications taken 0.4 0.8 4.9 0.7 0.9 0.8 -1.1 1.0 -0.5 -0.6 -0.6 -0.4 0.2 0.9 2.2 -0.1 0.5
Average weekly spirits intake 1.7 2.2 6.9 2.6 1.1 0.8 0.6 1.1 2.5 0.7 -0.4 1.0 0.5 1.1 1.8 2.4 1.1
Sensitivity / hurt feelings 0.3 0.6 3.3 1.1 -0.9 -0.7 0.6 0.0 0.3 0.3 0.6 0.3 -0.8 -0.7 0.1 1.8 -0.5
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.7 -0.4 -0.9 -1.0 0.9 0.4 0.3 1.0 1.1 1.3 1.1 -1.0 0.3 0.2 -0.9
Hearing difficulty/problems: Yes 0.5 0.8 2.1 0.9 0.9 0.7 -0.3 -1.0 1.4 -0.7 -1.3 -0.4 -0.4 0.7 0.7 1.5 0.0
Relative age of first facial hair 0.3 0.5 2.2 0.8 -0.7 -0.3 0.4 0.3 0.8 -0.2 0.9 0.2 -1.5 -0.5 -1.0 1.0 -0.0
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 4.3 1.1 1.5 1.3 2.1 0.9 1.2 -0.4 -1.7 -0.3 -0.1 1.2 1.6 0.5 0.8
Ever used hormone-replacement therapy (HRT) 3.3 4.2 9.4 -3.1 -2.4 -2.4 -2.3 -0.8 -1.0 0.9 1.3 0.2 -0.1 -2.5 -3.0 -2.4 -2.6
Ever had hysterectomy (womb removed) 0.5 0.6 2.1 -1.1 -0.4 -0.5 -1.0 0.3 -0.9 0.6 0.2 0.4 0.6 -0.5 -1.5 -1.0 -0.8
Systolic blood pressure, automated reading 2.0 5.9 20.8 -3.5 -1.7 -2.1 -4.6 -1.2 -1.3 1.0 0.3 -0.3 0.8 -2.5 -1.3 -4.0 -3.7
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.2 -0.0 0.7 0.6 1.0 0.1 0.0 -1.1 -1.5 -0.6 -0.5 0.5 0.1 -0.1 -0.1
Angina 0.9 1.1 4.8 0.8 1.0 0.9 0.1 -0.4 0.8 -0.6 -2.2 -1.7 -1.9 0.7 0.4 0.1 0.3
Medication for hormone replacement therapy 1.3 1.4 3.3 -0.6 -1.3 -1.4 1.2 -1.3 1.7 0.5 0.2 -0.7 -1.0 -1.4 -1.7 -0.4 -1.8
Vitamin and mineral supplements 0.2 0.2 0.8 0.6 0.2 -0.1 -0.9 0.7 0.5 0.5 -0.3 0.6 0.5 0.1 0.2 0.3 -0.4
Supplements: Zinc 1.6 1.7 3.3 -1.1 -1.8 -1.5 0.5 -0.8 -1.3 1.3 1.8 1.0 1.5 -1.6 -1.3 -0.6 -1.3
Medication: Co-codamol 0.7 0.9 2.4 -1.0 0.9 0.7 -0.6 -1.5 0.3 -1.5 -1.1 -0.9 -0.7 0.6 0.6 -1.1 0.2
Medication: Metformin 1.0 1.4 3.7 0.5 1.3 1.3 -0.6 0.9 -0.9 -1.8 -1.2 -1.2 -1.0 1.2 1.9 -0.7 0.7
Diabetes (father) 0.2 0.2 0.8 -0.3 -0.0 0.0 0.9 0.2 -0.3 0.5 0.4 -0.9 -0.2 0.1 0.3 -0.8 0.2
Diabetes (mother) 0.6 0.7 4.4 0.5 0.5 0.2 -0.2 0.1 2.1 0.2 -0.5 1.2 1.1 0.4 0.7 1.1 0.6
Severe depression (siblings) 1.8 2.0 5.3 -2.2 -0.1 0.1 -1.8 -2.3 -1.6 -1.0 -0.3 -2.1 -0.5 -0.0 -0.2 -2.1 -0.9
Pack years adult smoking proportion 0.2 0.3 1.3 0.0 0.4 0.5 -0.8 -0.2 -0.2 -1.1 -0.5 -0.9 0.0 0.6 -0.2 -0.5 -0.1
Impedance of leg (right) 0.1 0.6 2.3 0.2 0.8 0.9 -0.4 -1.1 -0.0 -0.5 0.3 -0.5 0.2 1.0 1.5 0.4 1.1
Leg fat-free mass (left) 0.0 0.1 0.3 -0.2 -0.1 -0.2 0.2 0.5 -0.3 -0.6 -0.2 0.2 0.2 -0.1 0.5 -0.5 -0.3
Trunk fat percentage 0.1 0.4 2.0 0.1 0.2 -0.0 -1.4 0.5 -0.1 0.0 0.0 0.5 1.2 0.0 1.2 -0.1 -0.1
Hand grip strength (right) 0.3 0.9 2.8 -1.7 -1.0 -0.9 0.8 -0.9 -0.9 -0.2 0.5 -0.8 -0.4 -1.0 -1.1 -1.2 -1.0
Townsend deprivation index at recruitment 1.3 1.8 5.7 -0.8 -1.6 -1.6 -2.4 0.6 -1.7 0.2 0.7 0.3 0.5 -1.7 -0.9 -1.3 -2.2
Current tobacco smoking 0.8 1.3 3.6 -1.2 -1.3 -1.5 -1.9 -0.7 -0.8 0.7 0.9 1.1 0.9 -1.4 -1.0 -0.6 -1.1
Average weekly fortified wine intake 0.4 0.5 1.8 0.4 -0.4 -0.3 0.3 1.2 0.2 0.5 0.7 1.1 1.0 -0.3 -0.4 1.3 -0.3
Maternal smoking around birth 0.5 0.7 2.5 1.6 0.7 0.6 1.0 0.9 0.8 0.4 -0.2 0.8 0.2 0.8 0.9 1.2 0.9
Fed-up feelings 0.2 0.4 2.8 0.3 0.3 0.4 1.0 -0.6 0.7 -0.6 -0.0 0.6 -0.0 0.4 0.4 1.7 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.1 -0.4 -0.7 -0.8 0.2 0.2 0.1 0.0 0.5 0.9 0.5 -0.7 0.1 -0.2 -1.1
Relative age voice broke 1.5 2.3 10.1 -0.2 -2.2 -1.8 0.1 0.0 -0.2 1.3 3.2 2.2 0.5 -1.8 -1.8 0.8 -1.1
Taking other prescription medications 1.0 1.6 4.8 2.1 -0.1 -0.2 1.1 2.2 0.7 1.5 1.0 1.5 1.2 0.1 0.9 1.8 0.5
Age when periods started (menarche) 0.6 1.5 5.0 -1.3 -1.3 -1.0 0.2 -1.0 -0.3 1.1 2.2 0.5 1.7 -0.7 -1.1 -1.9 -0.8
Bilateral oophorectomy (both ovaries removed) 1.7 2.0 5.6 -1.4 -1.9 -1.8 -0.8 0.0 -1.4 0.8 0.8 -0.1 -0.5 -2.0 -2.4 -1.5 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 2.9 0.5 0.0 0.0 -1.7 0.0 -1.4 -0.2 0.9 -0.0 0.7 0.3 1.1 -0.7 0.0
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 3.8 0.1 -0.6 -0.4 0.6 1.9 -0.5 0.9 1.6 1.9 1.4 -0.2 0.1 0.8 0.3
Qualifications: CSEs or equivalent 0.9 1.2 2.2 -1.3 -1.3 -1.4 -0.4 -0.7 -0.7 1.0 1.3 0.4 1.5 -1.5 -1.1 -0.5 -1.1
Serious illness, injury or assault to yourself 0.5 0.7 2.7 0.2 0.3 0.0 1.6 0.4 1.4 0.3 -0.8 -0.2 0.1 -0.1 1.6 0.6 -0.7
High blood pressure 0.3 0.9 3.5 -0.6 -0.2 -0.1 -1.9 1.3 -0.6 0.5 0.9 1.0 0.3 -0.2 1.1 -1.8 0.1
Hayfever, allergic rhinitis or eczema 2.2 4.8 17.6 1.9 2.7 2.7 2.2 0.7 1.8 -0.7 -1.5 0.3 0.1 2.7 4.2 2.3 2.6
Multivitamins +/- minerals 0.3 0.3 1.3 -0.4 -0.6 -0.5 1.1 -0.4 -0.2 -0.1 0.2 -0.4 -0.7 -0.5 -1.0 -0.5 -0.2
Stomach or abdominal pain in last month 1.0 1.2 2.8 -1.4 -1.3 -1.3 -1.3 -0.8 0.4 0.8 0.8 -0.1 0.8 -1.3 -0.5 -1.7 -1.5
Supplements: Glucosamine 0.4 0.5 3.0 -0.2 -0.3 -0.5 -0.8 1.7 -0.2 0.4 -0.1 0.9 0.2 -0.6 -0.4 0.7 -0.4
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 3.0 -1.4 -0.3 -0.4 -0.6 -1.1 -1.1 -0.5 -0.2 -1.0 -0.5 -0.5 0.0 -1.7 -0.7
Medication: Atenolol 0.7 0.8 2.9 0.3 1.2 1.1 -1.2 -0.1 -0.8 -0.7 -1.2 -0.4 0.3 1.0 1.7 -0.7 0.7
Medication: Levothyroxine sodium 0.3 0.6 3.3 -0.7 -0.5 -0.5 0.3 -1.8 0.9 0.5 0.6 0.6 0.3 -0.6 -0.9 -0.6 -0.4
Sitting height 0.2 1.7 5.3 -0.7 -1.9 -1.7 -1.1 -0.1 1.1 0.1 2.3 2.0 0.6 -1.7 -0.9 -0.2 -1.3
Chronic bronchitis/emphysema (father) 0.8 1.0 6.5 0.2 0.5 0.6 -0.2 2.5 -2.2 -0.4 0.2 0.8 -0.2 0.6 -0.3 0.4 0.3
High blood pressure (mother) 1.1 1.5 3.6 0.5 1.6 1.4 -0.8 0.1 -0.1 -1.6 -1.9 -1.8 -1.8 1.3 1.2 -0.4 0.7
Body mass index (BMI) 0.0 0.2 0.6 0.0 0.3 0.1 -0.4 0.4 0.6 0.1 -0.8 -0.6 0.1 0.1 0.8 -0.4 -0.4
Impedance of leg (left) 0.1 0.5 2.2 0.2 0.9 0.9 -0.2 -0.6 0.3 -0.1 0.1 -0.5 0.3 0.9 1.5 0.5 1.0
Leg predicted mass (left) 0.0 0.1 0.4 -0.1 -0.0 -0.2 0.1 0.5 -0.3 -0.6 -0.3 0.1 0.1 -0.1 0.5 -0.5 -0.3
Trunk fat mass 0.1 0.4 2.0 0.1 0.5 0.2 -1.4 0.5 -0.0 -0.5 -0.4 0.1 0.8 0.3 1.4 -0.2 0.1
Waist circumference 0.2 0.6 3.1 0.2 0.8 0.6 -1.8 0.4 -0.1 -0.9 -0.6 -0.3 0.1 0.7 1.5 0.0 0.2
Number of incorrect matches in round 0.3 0.5 1.9 0.1 -1.0 -0.9 -1.0 0.6 0.4 0.1 1.4 0.6 0.2 -0.8 -0.5 -0.3 -0.5
Past tobacco smoking 0.3 0.5 2.7 -0.7 -0.7 -0.7 0.7 0.5 -0.3 0.4 0.9 -0.5 0.4 -0.6 0.2 -1.6 -0.8
Alcohol usually taken with meals 0.3 0.5 1.5 -1.0 -0.6 -0.5 -0.3 -1.2 -0.2 -0.2 -0.4 -0.8 -0.5 -0.7 -0.9 -0.8 -0.4
Nervous feelings 0.6 1.2 2.8 1.7 0.8 0.8 -1.1 0.9 1.1 -0.9 -0.7 -0.0 -1.5 0.7 1.6 0.9 1.2
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 1.1 -1.0 0.3 0.1 -0.1 -0.7 0.8 -1.1 -0.7 -0.1 -0.7 0.1 0.1 -1.0 -0.0
Hearing difficulty/problems with background noise 0.5 0.8 3.3 0.9 0.8 0.8 0.8 0.1 1.5 -0.5 -1.0 -0.7 -1.8 0.6 0.1 1.0 0.5
Hair/balding pattern: Pattern 2 0.3 0.4 1.4 0.5 0.7 0.8 -0.1 0.4 -0.5 -1.2 0.2 -0.5 -0.7 0.7 1.0 0.5 0.6
Had menopause 2.2 2.8 6.9 -1.8 -1.7 -1.8 -2.1 0.2 -1.8 1.5 1.1 1.4 1.9 -1.6 -2.6 -1.1 -1.5
Had other major operations 0.5 0.6 2.0 -0.2 -0.5 -0.4 0.1 1.4 -0.9 1.1 1.0 1.1 0.7 -0.4 0.5 -0.5 -0.4
Forced vital capacity (FVC) 0.1 0.3 1.6 -0.9 0.3 0.1 -0.6 -0.8 -0.1 -0.6 -0.2 -0.3 -0.2 0.1 0.7 -1.3 0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 3.5 0.8 0.6 0.6 -1.9 -0.6 -1.6 -1.1 0.4 -0.1 0.4 0.8 1.1 0.2 0.7
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.2 -0.3 -0.8 -0.9 -0.7 -0.0 0.3 1.0 0.1 0.0 0.3 -1.0 -0.6 0.0 -1.1
Qualifications: None of the above 0.9 2.0 10.3 -0.1 1.1 1.1 -3.2 -0.9 0.2 -2.1 -1.5 -1.6 -1.2 1.0 0.7 -1.1 1.1
Financial difficulties in last 2 years 1.0 1.3 3.4 1.7 1.1 1.1 1.8 1.2 0.5 -0.9 -0.8 -0.6 -1.2 1.1 0.9 1.4 1.2
Mouth/teeth dental problems 0.6 0.9 7.4 -0.0 -0.3 -0.4 -2.7 1.0 -1.5 0.1 0.2 -0.0 -0.9 -0.4 -0.2 -0.4 -0.6
Heart attack 0.3 0.3 1.4 0.4 -0.6 -0.6 -0.9 0.2 -1.2 0.1 0.1 -0.2 -0.5 -0.5 -0.6 -0.6 -0.5
Allergy 1.0 2.2 8.8 -1.2 -1.7 -1.6 -1.5 -0.3 -1.1 0.9 1.2 0.1 0.5 -1.6 -3.0 -2.0 -1.8
Pain all over the body in last month 0.3 0.4 1.1 0.9 0.6 0.5 0.8 -0.3 0.3 -0.8 -1.1 -0.4 -0.7 0.6 0.3 0.5 0.1
Diabetes (self-reported) 0.4 0.6 1.9 -1.2 -0.1 0.0 -0.4 -0.4 -1.3 -0.4 0.8 0.6 0.9 -0.1 1.1 -1.4 -0.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.3 -1.3 -0.1 0.2 0.1 -0.1 -0.0 0.2 0.6 0.7 0.3 -0.2 1.5 -0.5 -0.9
Medication: Ramipril 1.0 1.3 3.2 1.2 0.4 0.3 -1.3 1.8 -0.5 0.5 1.1 1.6 1.8 0.7 1.4 0.0 1.3
Medication: Simvastatin 0.3 0.4 2.0 -0.1 -0.3 -0.4 -1.4 -0.3 -0.3 0.5 0.4 0.4 0.8 -0.3 0.7 -0.6 -0.8
Fluid intelligence score 2.6 5.4 14.1 2.8 2.7 3.0 1.3 3.0 -0.0 -0.4 -0.8 0.6 0.1 3.0 3.8 1.8 3.7
Illnesses of siblings 2.5 3.5 11.4 -1.2 -2.0 -1.5 2.1 2.2 -1.0 1.8 3.4 2.3 2.5 -1.6 -0.9 -0.1 -0.5
Neuroticism score 0.6 1.3 6.1 2.3 0.6 0.7 0.2 0.7 0.8 -0.4 0.1 0.6 -0.6 0.8 1.3 2.5 1.0
Weight 0.1 0.3 1.8 0.1 0.4 0.3 -0.6 0.6 -0.0 -0.6 -0.5 -0.1 0.2 0.3 1.3 -0.3 -0.1
Impedance of arm (right) 0.4 1.7 5.3 1.0 -0.7 -0.4 -0.6 0.4 -2.0 0.0 2.1 2.3 1.4 -0.3 0.5 2.0 0.9
Arm fat percentage (right) 0.0 0.1 0.6 0.4 0.1 -0.1 -0.7 0.4 -0.1 0.1 -0.2 -0.1 0.7 -0.1 0.7 0.2 0.0
Trunk fat-free mass 0.1 0.4 1.5 -0.1 0.6 0.6 0.1 -0.0 -0.2 -1.2 -0.9 -0.8 -0.7 0.6 0.8 -0.7 0.3
Hip circumference 0.1 0.3 1.5 0.6 0.5 0.5 -0.4 0.4 0.5 -0.5 -0.3 -0.2 0.1 0.5 1.2 0.2 0.3
Time employed in main current job 0.7 0.8 3.5 0.7 1.2 1.1 1.9 0.3 0.0 0.8 0.2 0.3 0.7 1.3 0.5 -0.2 1.3
Alcohol intake versus 10 years previously 0.3 0.5 3.8 0.3 0.3 0.3 -0.1 -0.6 -0.1 -0.6 -0.7 -1.0 -2.0 0.0 -0.1 0.6 -0.2
Father’s age at death 0.2 0.3 1.7 -0.3 0.4 0.4 -0.5 -1.3 0.4 -0.6 -0.6 -0.4 -0.6 0.3 0.3 -0.6 -0.0
Worrier / anxious feelings 0.5 1.0 4.0 1.4 0.2 0.5 -0.6 2.0 -0.6 -0.9 0.7 0.8 -0.3 0.5 1.5 1.3 0.8
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.1 0.7 1.2 1.0 1.0 0.4 -0.1 -0.9 -1.4 -0.2 -0.3 1.1 1.2 0.8 0.9
Falls in the last year 3.8 5.1 8.2 2.1 2.7 2.9 1.4 -0.3 1.0 -2.7 -2.9 -2.5 -2.8 2.8 2.3 1.0 2.2
Hair/balding pattern: Pattern 3 1.3 2.0 5.3 -2.3 -1.4 -1.5 -0.0 -1.2 -0.5 1.9 0.5 0.5 0.9 -1.6 -1.9 -1.3 -1.8
Number of live births 0.6 0.9 1.5 -0.9 -1.2 -1.1 -0.9 -1.1 0.4 0.9 1.2 0.9 0.6 -1.1 -0.8 0.7 -0.9
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 1.8 -1.0 0.2 0.0 -0.5 -0.2 0.2 -0.5 0.0 -0.3 -0.7 -0.0 0.8 -1.4 -0.1
Pulse rate 0.9 1.5 8.2 -0.6 -1.0 -0.9 1.2 0.2 2.9 1.6 0.8 -0.6 0.0 -0.9 -1.0 -1.4 -1.0
Happiness 0.5 0.6 2.4 0.1 -0.4 -0.5 -1.6 0.4 -0.3 0.6 0.7 1.2 1.1 -0.4 0.5 0.9 0.4
Noisy workplace 0.6 0.8 4.0 0.3 0.7 0.6 -0.1 -2.0 0.8 0.0 -1.2 -1.8 -0.1 0.5 0.2 -0.1 -0.0
Qualifications: A levels/AS levels or equivalent 0.3 0.6 1.6 -1.0 0.4 0.5 0.6 -0.8 0.6 0.9 0.4 0.4 1.3 0.6 0.8 -1.0 0.8
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.4 0.1 -0.1 0.0 1.2 -1.5 1.2 0.4 0.0 -1.0 0.3 0.1 -0.1 -0.8 0.8
Mouth/teeth dental problems: Dentures 0.1 0.3 1.3 -0.3 -0.1 0.1 1.1 0.4 0.1 -0.1 0.5 -0.4 -0.5 0.1 -0.7 -0.6 0.6
Asthma 0.1 0.2 0.8 -0.1 -0.2 -0.3 0.0 -0.9 0.5 -0.0 -0.5 -0.6 -0.2 -0.3 0.4 0.4 -0.8
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.2 5.5 0.2 1.3 1.2 0.9 -1.0 1.0 -0.6 -1.6 -2.3 -0.3 1.3 0.3 0.2 0.7
Medication: Cholesterol lowering 0.4 0.7 1.8 1.2 -0.3 -0.3 -0.7 1.0 -0.9 0.5 1.0 1.4 1.2 -0.0 0.6 0.5 0.6
Depression (self-reported) 0.8 1.0 2.5 -1.3 -1.3 -1.3 0.2 -1.4 -0.1 0.8 0.3 -0.6 0.1 -1.4 -0.8 -1.1 -1.6
Medication: Lansoprazole 0.4 0.4 2.1 -0.2 0.6 0.5 -0.9 0.6 -1.4 0.4 -0.5 -0.2 0.6 0.6 1.0 -0.4 0.4
Prospective memory result 0.8 1.0 3.8 -1.3 -1.0 -1.0 -0.1 -0.6 -0.2 -0.2 -0.2 -0.9 -0.8 -1.1 -0.9 -1.6 -1.9
Lung cancer (father) 0.5 0.6 2.3 -0.7 0.4 0.4 -0.9 -0.6 -0.4 -1.2 0.7 -0.6 0.1 0.6 1.2 -1.5 -0.1
Illnesses of mother 1.1 1.4 2.4 -1.2 -1.5 -1.5 0.1 -0.5 -0.1 1.5 1.2 -0.3 0.6 -1.6 -1.1 -1.5 -1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 2.9 0.7 1.2 1.1 1.2 0.6 1.0 -1.2 -0.8 -0.3 -1.4 1.1 1.7 0.2 1.1
Pulse wave Arterial Stiffness index 0.3 0.3 1.2 0.5 0.2 0.0 -0.3 -1.1 0.7 -0.1 -0.4 0.9 -0.1 0.0 0.8 0.6 0.2
Impedance of arm (left) 0.4 1.9 6.4 0.9 -0.8 -0.6 -0.4 0.9 -2.2 0.3 2.2 2.5 1.5 -0.5 0.6 2.2 0.6
Arm fat mass (right) 0.0 0.1 0.6 0.0 -0.0 -0.3 -0.8 0.3 0.0 0.0 -0.3 -0.1 0.7 -0.2 0.7 -0.1 -0.3
Trunk predicted mass 0.1 0.5 1.7 -0.1 0.7 0.7 0.2 -0.1 -0.3 -1.3 -1.0 -0.9 -0.7 0.7 0.8 -0.7 0.4
Standing height 0.1 0.7 2.6 -0.1 0.0 0.1 -1.0 0.3 -1.4 -1.6 0.8 1.2 0.5 0.2 1.1 0.2 0.3
Length of working week for main job 2.7 3.0 10.8 2.2 1.6 1.9 3.3 1.6 0.0 -0.3 -0.3 -1.1 -1.1 1.8 2.1 2.2 1.9
Exposure to tobacco smoke at home 0.3 0.4 1.0 0.4 0.6 0.7 -0.4 0.3 1.0 -0.6 -0.2 0.4 0.3 0.7 0.9 0.1 0.8
Breastfed as a baby 1.0 1.3 4.4 -1.0 0.3 0.5 -1.8 -2.1 0.2 -0.5 -0.4 -1.9 -1.1 0.2 1.2 -1.4 -0.4
Tense / ‘highly strung’ 0.3 0.4 2.0 1.1 0.3 0.3 0.1 1.4 -0.7 0.8 -0.3 0.3 0.0 0.3 0.4 0.8 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.4 0.3 0.1 -0.1 -1.1 0.9 1.2 0.2 -0.3 0.1 -0.5 0.2 0.3 0.2 0.3
Hair/balding pattern: Pattern 4 0.5 1.3 2.8 -0.3 -1.4 -1.4 1.5 1.7 1.0 1.3 1.0 0.7 0.5 -1.4 -0.7 -0.9 -1.2
Birth weight of first child 0.4 0.8 2.8 -0.1 -0.9 -0.8 1.7 0.5 -0.2 1.2 1.1 0.8 0.6 -0.9 -1.0 1.0 -0.7
Peak expiratory flow (PEF) 0.2 0.4 1.8 -0.1 -0.2 -0.3 -1.3 1.1 0.8 0.4 0.4 0.7 -0.1 -0.3 0.9 -0.3 0.1
Pulse wave reflection index 0.6 0.7 2.7 0.6 0.5 0.5 -0.4 -1.6 -1.4 -1.0 -0.6 0.2 -0.2 0.4 1.4 1.0 0.2
Ever highly irritable/argumentative for 2 days 0.2 0.2 1.2 0.5 -0.2 -0.4 -0.7 1.1 0.3 0.3 -0.2 0.4 -0.3 -0.2 -0.2 0.4 -0.4
Loud music exposure frequency 0.7 0.8 3.0 0.8 0.7 0.5 1.5 1.7 0.3 -0.3 -1.3 -1.0 -1.1 0.5 0.2 0.2 0.0
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 2.3 -1.5 1.1 0.8 1.4 -1.4 0.7 -0.0 -1.0 -0.1 0.6 0.7 -0.1 -1.0 -0.7
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 2.0 -0.0 0.5 0.5 1.4 -0.2 0.9 -0.7 -0.3 0.7 1.3 0.5 1.0 0.7 0.5
Blood clot in the leg (DVT) 1.4 1.8 5.7 -1.0 -1.2 -1.3 -1.6 0.3 -1.8 -0.8 0.0 0.3 -2.0 -1.5 -2.4 0.2 -1.6
Medication: Paracetamol 1.7 2.8 12.0 -1.2 1.1 0.8 -1.3 -3.5 0.4 -2.4 -2.3 -2.1 -1.2 0.6 1.9 -1.2 -0.1
Headache pain in last month 0.3 0.6 1.8 0.3 1.1 1.1 0.3 -0.0 -0.4 -1.2 -1.3 -0.8 -0.7 0.7 0.7 0.6 -0.2
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 5.1 -1.5 -0.8 -0.9 1.1 -0.8 0.8 0.1 -0.5 -0.6 -0.7 -1.0 -2.3 -0.2 -1.5
Glaucoma (self-reported) 0.4 0.4 1.0 -0.8 -0.8 -0.6 1.0 0.7 -0.4 0.0 0.5 -0.3 0.7 -0.7 -0.2 -0.6 -1.0
Gout (self-reported) 0.2 0.2 1.2 0.5 -0.1 0.1 0.6 0.3 0.2 -0.7 0.4 0.1 -0.8 0.1 0.1 1.1 0.4
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 2.4 -1.3 -0.7 -0.7 0.5 -1.5 0.3 1.2 0.6 1.2 0.6 -0.9 -1.0 -0.2 -0.9
Medication: Amlodipine 1.5 2.1 5.2 -1.6 -1.1 -1.1 -2.3 1.1 -1.9 0.6 1.3 2.0 1.0 -1.3 -0.6 -1.8 -1.6
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.2 -1.4 -0.7 -0.8 -0.5 -0.5 -0.3 0.4 -0.1 -0.7 0.6 -0.9 -0.0 -1.1 -1.5
Birth weight 1.6 3.5 7.6 2.1 2.2 2.3 2.2 0.1 1.0 -1.6 -1.9 -1.5 -2.8 2.1 1.6 1.5 1.9
Chronic bronchitis/emphysema (mother) 1.7 1.9 3.9 1.2 1.6 1.7 -0.5 -0.8 0.6 -1.9 -1.7 -2.0 -1.2 1.8 1.1 -0.1 1.6
High blood pressure (siblings) 2.4 3.5 11.7 0.3 1.8 1.3 -2.4 -2.1 1.7 -2.3 -3.4 -1.7 -2.8 1.2 1.4 0.0 -0.0
Forced vital capacity (FVC), Best measure 0.2 0.9 2.9 0.2 1.2 1.1 0.9 -0.1 0.4 -1.3 -0.7 -0.1 -1.0 1.1 1.7 0.4 1.2
Body fat percentage 0.1 0.4 2.5 0.4 0.7 0.4 -1.1 0.7 0.3 -0.2 -0.4 -0.1 0.7 0.5 1.6 0.1 0.3
Leg fat percentage (right) 0.3 1.2 3.8 0.6 1.4 1.3 -1.2 0.0 0.8 -1.0 -1.3 -1.6 -0.3 1.3 1.9 -0.1 0.7
Arm fat-free mass (right) 0.1 0.5 2.5 -0.9 0.4 0.2 -0.4 0.0 0.2 -0.8 -0.9 -1.0 -0.3 0.2 0.5 -1.6 -0.4
Exposure to tobacco smoke outside home 1.1 1.5 3.2 -0.6 -1.8 -1.6 1.1 0.4 -0.0 1.4 1.8 0.8 1.2 -1.6 -1.7 0.3 -1.1
Comparative body size at age 10 0.2 0.7 2.1 -0.1 1.2 1.2 0.7 0.2 0.1 0.0 -0.6 -1.0 -0.1 1.0 1.4 -0.5 1.0
Number of full brothers 0.4 0.5 2.8 0.1 -0.3 -0.4 0.7 -0.8 0.0 0.3 0.1 0.8 0.4 -0.4 -1.7 1.5 -0.3
Worry too long after embarrassment 0.8 1.4 4.5 -0.6 -1.0 -1.0 0.7 0.1 0.5 2.1 1.9 1.3 2.1 -0.8 0.7 -0.3 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.2 0.1 -0.8 -0.9 -0.6 0.6 -0.9 0.5 0.2 0.1 0.3 -0.7 -1.0 0.2 -1.1
Wheeze or whistling in the chest in last year 0.8 1.5 3.9 0.9 1.3 1.1 -0.5 -1.3 -0.6 -1.7 -2.0 -0.9 -1.7 1.0 0.4 1.4 0.5
Number of children fathered 0.3 0.3 1.2 0.9 0.3 0.3 -0.3 -0.8 1.1 0.1 -0.3 -0.3 0.6 0.5 0.2 0.6 0.6
Reason for reducing amount of alcohol drunk: Health precaution 2.6 3.0 8.2 1.7 2.0 2.3 -0.3 -1.3 0.4 -2.5 -0.7 -0.8 -1.6 2.4 1.8 0.8 2.9
Age at first live birth 0.2 0.3 1.3 0.8 0.3 0.4 0.3 0.5 -0.6 -1.1 -0.4 -0.4 -1.0 0.4 0.3 -0.1 0.0
Pulse wave peak to peak time 0.2 0.3 1.3 -0.5 -0.2 0.1 0.2 1.1 -0.7 -0.2 0.3 -1.0 -0.0 0.1 -0.7 -0.6 -0.0
Health satisfaction 0.4 0.5 2.2 1.2 -0.3 -0.3 0.4 0.6 0.4 0.7 0.7 0.9 0.6 -0.3 0.1 1.5 0.8
Shortness of breath walking on level ground 0.5 0.6 2.0 -0.1 -1.0 -1.0 0.0 -0.7 -0.1 0.1 0.2 -1.0 -0.7 -1.0 -0.3 -1.4 -1.3
Qualifications: College or University degree 0.2 0.5 1.4 -0.3 -0.7 -0.6 0.2 0.2 0.0 1.2 1.2 1.1 1.0 -0.4 0.6 -0.4 0.3
Eye problems/disorders: None of the above 0.4 0.5 2.6 -0.5 -0.5 -0.6 -1.6 -1.0 -0.3 -0.1 -0.1 0.3 -0.6 -0.6 -0.9 0.1 -0.2
Mouth/teeth dental problems: Loose teeth 0.6 0.7 4.9 -0.2 -0.4 -0.2 0.5 -1.4 2.2 -0.0 -0.3 -1.2 -0.1 -0.2 -0.9 -0.0 -0.2
Emphysema/chronic bronchitis 0.9 1.0 2.3 -0.1 0.9 1.1 -0.5 -1.1 -1.4 -1.4 -0.5 0.6 0.5 1.1 0.5 1.2 1.5
Medication for pain relief, constipation, heartburn 0.5 0.8 4.7 0.6 -0.3 -0.2 1.3 2.2 0.5 0.3 0.2 0.7 -1.5 -0.3 -1.1 0.5 0.1
Neck or shoulder pain in last month 0.8 1.1 2.7 0.7 1.2 1.3 0.9 0.7 1.2 -1.1 -1.1 -0.9 -1.3 1.2 0.6 0.1 1.6
Medication: Blood pressure 1.1 2.0 10.7 1.8 1.6 1.6 -0.7 0.5 -0.2 -0.2 -0.5 -0.3 0.1 1.7 3.3 -0.3 2.3
Angina (self-reported) 0.9 1.2 4.4 0.8 1.0 0.9 0.1 -0.5 0.5 -0.8 -2.1 -1.8 -2.0 0.8 0.5 0.1 0.4
Migraine (self-reported) 0.8 1.0 4.1 -0.6 0.8 0.7 0.2 -2.0 1.4 -0.9 -1.2 -1.4 -0.6 0.6 1.0 -1.0 0.1
Medication: Ibuprofen 1.6 1.9 8.7 -0.3 1.5 1.5 1.1 -1.2 1.2 -0.8 -1.9 -2.9 -0.8 1.5 0.3 -0.4 0.9
Medication: Allopurinol 0.4 0.5 1.5 1.1 0.4 0.4 0.9 1.2 -0.4 -0.7 -0.3 -0.2 -0.1 0.4 0.5 1.1 0.8
Medication: Omeprazole 0.3 0.4 3.6 0.3 0.1 0.3 -1.9 -0.5 0.4 0.2 0.3 -0.6 0.3 0.4 0.7 -0.5 -0.0
Medication: Seretide 50 evohaler 0.5 0.6 1.6 0.6 0.8 1.0 0.0 0.9 0.2 -1.3 -0.4 0.1 0.2 1.0 0.9 1.0 1.0
Mean time to correctly identify matches 0.9 1.7 8.5 -0.1 -0.3 -0.2 -0.2 1.0 0.4 1.3 1.8 2.9 2.3 -0.0 0.5 1.7 0.6
Heart disease (mother) 4.3 5.3 11.4 -0.9 -3.0 -3.4 0.8 0.3 0.0 2.9 2.2 3.1 2.9 -3.2 -1.1 0.0 -3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 3.9 1.7 0.5 0.6 -0.3 2.0 0.1 -0.8 0.4 1.0 -0.1 0.8 0.1 1.1 0.9
Whole body fat mass 0.1 0.3 1.7 -0.0 0.3 0.1 -1.1 0.5 0.0 -0.2 -0.3 0.1 0.9 0.2 1.3 -0.2 -0.1
Leg fat mass (right) 0.2 0.6 2.2 0.1 0.8 0.6 -0.9 0.0 0.5 -0.7 -1.1 -1.1 0.2 0.7 1.5 -0.5 0.2
Arm predicted mass (right) 0.1 0.4 1.6 -0.6 0.5 0.4 -0.0 0.2 0.3 -0.9 -1.0 -1.1 -0.4 0.4 0.6 -1.3 -0.1
Pulse rate, automated reading 0.3 1.1 8.8 -0.9 -0.2 -0.2 0.8 -0.3 3.0 0.1 0.5 -0.4 0.1 -0.1 -0.2 -1.8 -1.1
Alcohol intake frequency. 0.1 0.2 0.8 0.4 -0.2 -0.2 0.6 0.9 -0.0 -0.3 0.1 -0.0 -0.4 -0.1 -0.8 0.4 -0.1
Comparative height size at age 10 0.2 0.9 5.2 -0.9 -0.4 -0.2 -1.3 0.7 -2.3 -1.0 1.0 1.0 0.7 -0.3 0.3 -0.5 -0.2
Number of full sisters 0.9 1.1 5.3 0.1 0.0 0.0 -0.1 -0.8 1.1 -1.5 -1.8 -1.4 -2.3 -0.2 -0.2 0.5 -1.0
Suffer from ‘nerves’ 0.4 0.7 2.5 -0.1 -0.7 -0.8 -0.0 1.6 1.2 -0.1 -0.5 -0.1 -0.9 -0.9 -0.9 -0.9 -0.9
Overall health rating 0.7 1.5 4.9 1.0 1.7 1.5 -0.2 -0.2 -0.4 -1.4 -1.5 -0.6 -0.0 1.5 2.2 1.1 1.4
Chest pain or discomfort 0.3 0.4 2.1 0.3 0.4 0.2 -0.6 -0.5 0.6 -1.0 -1.4 -0.3 -0.5 0.2 0.3 0.4 -0.7
Had major operations 0.6 0.7 1.8 0.8 1.1 1.0 -0.5 -0.9 0.4 -0.7 -1.3 -0.4 -0.4 1.0 0.7 0.6 0.8
Age at last live birth 0.2 0.3 0.7 0.9 0.5 0.6 0.6 0.3 -0.1 -0.7 -0.3 -0.4 -0.5 0.7 -0.0 0.0 0.5
Family relationship satisfaction 0.5 0.6 4.2 -0.6 -0.5 -0.5 -2.0 0.4 -1.4 -0.3 0.1 -0.2 0.0 -0.7 -0.6 -0.2 -0.5
Leg pain on walking 0.8 1.0 4.8 1.1 0.4 0.4 2.2 0.4 1.8 0.3 -0.1 0.8 0.2 0.3 0.6 1.4 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 3.0 -0.0 -0.6 -0.6 1.7 -0.8 0.2 0.7 -0.3 -0.7 -0.8 -0.5 -1.7 0.3 -1.1
Commuting to job workplace: Car/motor vehicle 1.8 2.0 4.6 0.8 1.9 1.7 0.4 1.0 2.0 -1.6 -1.8 -0.6 -1.0 1.7 2.1 0.9 1.0
Illness, injury, bereavement, stress in last 2 years 1.2 1.5 5.2 -1.7 -1.1 -1.0 -2.3 0.1 -1.7 0.1 1.1 0.9 -0.0 -1.0 -1.4 -1.1 -1.1
Medication: Aspirin 0.9 1.2 4.0 -0.8 -0.9 -1.0 -0.6 -0.9 -1.4 0.9 1.1 0.5 2.0 -0.7 -0.6 -2.0 -0.5
Supplements: Vitamin C 0.7 0.8 4.4 -0.8 0.8 0.9 -0.1 -0.6 -0.4 -0.6 -0.7 -2.1 -0.8 0.7 0.5 -1.4 0.5
Knee pain experienced in last month 2.3 3.6 7.1 2.7 2.2 2.1 0.7 2.6 1.5 -1.6 -1.6 -0.0 -0.9 2.2 1.8 2.5 1.9
Hypertension (Self-reported) 0.4 1.1 5.0 -0.8 -0.4 -0.3 -2.2 1.4 -1.0 0.2 0.9 0.9 0.0 -0.3 0.5 -2.1 -0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.5 0.4 0.0 0.3 -0.4 -0.7 -0.1 0.4 0.4 0.0 -0.2 0.3 -0.5 -0.0 0.2
Illnesses of father: Heart disease 0.3 0.5 2.1 0.3 0.4 0.1 -0.3 1.2 0.7 0.1 -1.4 -1.1 -0.6 0.2 -0.3 -0.1 -0.5
Illnesses of siblings: Diabetes 0.6 0.7 1.7 0.3 -1.1 -1.1 -0.2 -0.4 -0.8 1.2 1.3 0.5 1.0 -0.9 -1.1 0.2 -0.5
Smoking status: Previous 0.7 1.1 2.5 1.1 1.3 1.3 0.1 -0.4 0.8 -1.0 -1.3 -0.4 -1.1 1.2 -0.1 1.6 1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.4 1.3 1.0 0.9 1.5 0.4 0.7 -0.8 -0.0 0.5 0.4 1.2 1.4 1.8 2.1
Whole body fat-free mass 0.0 0.3 1.0 -0.2 0.4 0.3 0.0 0.2 -0.2 -1.0 -0.8 -0.6 -0.4 0.3 0.7 -0.8 0.0
Leg fat-free mass (right) 0.0 0.1 0.7 -0.1 -0.1 -0.2 0.2 0.9 -0.2 -0.4 -0.3 0.3 0.1 -0.2 0.3 -0.4 -0.3
Arm fat percentage (left) 0.0 0.1 0.5 0.4 0.1 -0.1 -0.6 0.6 -0.0 0.1 -0.1 -0.1 0.6 -0.1 0.7 0.3 -0.0
Average weekly red wine intake 1.3 2.0 5.9 -1.5 -1.9 -1.6 0.1 -0.6 -0.8 0.9 2.4 1.4 2.0 -1.6 -0.8 -1.0 -1.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.9 0.6 0.0 -0.1 -0.9 1.4 0.1 -1.2 -0.4 -0.2 -1.4 -0.1 -0.1 0.3 -0.0
Mood swings 0.4 0.7 2.1 1.3 0.6 0.5 0.5 0.0 1.1 -0.6 -0.6 -0.4 -1.1 0.5 0.8 1.5 0.5
Loneliness, isolation 2.0 2.8 6.1 2.4 1.6 1.7 1.3 -0.1 2.3 -1.6 -0.7 0.1 -0.7 1.8 2.5 1.9 2.0
Long-standing illness, disability or infirmity 0.4 0.6 2.7 1.0 0.7 0.8 0.0 1.0 0.8 -0.8 -0.3 0.2 -0.2 0.9 1.7 0.6 0.5
Ever had bowel cancer screening 0.6 0.8 3.4 0.6 1.1 1.0 0.7 0.6 0.9 -0.3 -0.9 0.2 -0.6 0.9 1.8 0.2 1.0
Diabetes diagnosed by doctor 0.5 0.8 4.8 -0.3 0.7 0.8 -0.9 -0.1 -1.1 -1.0 0.1 0.3 0.4 0.7 2.2 -0.8 0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 3.3 -0.6 -1.0 -1.0 0.3 -0.1 0.1 0.8 0.4 0.3 0.2 -0.9 -1.8 -0.9 -0.9
Friendships satisfaction 0.6 0.8 3.9 -1.0 -0.2 -0.1 -2.0 -2.0 0.1 -1.0 0.3 -0.3 -0.1 -0.3 0.2 -0.3 -0.6
Qualifications: nursing, teaching 0.4 0.7 3.2 -1.0 -0.3 -0.4 0.9 -1.8 0.6 0.9 0.4 0.2 1.1 -0.2 1.1 -0.3 -0.1
Commuting to job workplace: Walk 2.9 3.2 5.5 -2.3 -2.1 -2.1 -1.5 -1.9 -0.5 1.3 1.8 0.5 0.9 -2.1 -1.6 -2.4 -2.3
Eye problems/disorders: Cataract 0.5 0.6 2.9 0.4 0.1 0.1 1.7 0.8 0.7 1.1 0.5 0.2 1.0 0.3 0.7 0.4 0.4
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.9 0.8 -0.4 -0.4 1.7 -0.4 0.5 0.8 0.1 0.4 0.7 -0.3 -0.0 0.7 0.1
Medication for cholesterol 3.3 5.0 14.3 3.5 2.1 2.3 2.0 0.1 1.3 -1.3 -1.3 -0.4 -2.1 2.3 1.5 3.8 3.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.8 -0.7 0.2 -0.2 -0.3 -0.2 -0.9 0.3 -0.9 -0.8 -0.1 -0.4 0.1 -0.4 -0.5
Back pain experienced in last month 0.2 0.3 1.3 -0.4 -0.1 -0.0 -1.0 -0.1 -1.2 -0.3 -0.1 -0.0 -0.3 -0.3 0.6 0.8 -0.3
Mineral and other dietary supplements 0.5 0.7 2.5 1.6 0.7 0.8 0.5 -0.2 1.1 -0.1 0.3 -0.0 -0.1 1.0 1.1 1.3 1.2
Breast cancer (self-reported) 2.3 2.7 7.1 2.3 1.8 1.8 1.5 1.4 0.1 -1.3 -1.3 0.8 -0.6 1.9 1.5 2.7 2.1
Asthma (self-reported) 0.1 0.2 0.6 0.1 -0.0 -0.1 -0.0 -0.7 0.5 -0.3 -0.7 -0.6 -0.6 -0.3 0.5 0.8 -0.8
Osteoporosis (self-reported) 0.6 0.8 1.8 -1.3 -1.0 -0.9 -0.4 -1.3 0.9 -0.3 0.5 -0.1 0.7 -0.9 -0.5 -1.3 -0.9
Osteoarthritis (self-reported) 0.6 0.8 2.5 0.1 1.1 1.1 0.1 0.1 0.8 -0.8 -0.8 -1.6 -1.6 1.0 0.0 -0.3 0.6
Medication: Aspirin 1.4 1.8 5.7 -1.1 -1.1 -1.1 -1.0 -0.9 -1.7 1.1 1.4 0.6 2.4 -0.8 -0.9 -2.4 -0.6
Medication: Gliclazide 0.6 0.7 2.8 -1.3 0.4 0.6 -0.4 -1.0 -1.7 -0.6 -0.3 -0.2 -0.0 0.3 1.2 -1.1 0.2
Illnesses of father: None of the above (group 1) 0.5 0.7 2.0 -0.1 -1.1 -0.6 0.6 0.1 -0.6 1.2 1.4 0.7 1.3 -0.6 -1.0 0.1 0.2
Smoking status: Current 1.4 2.2 4.7 -1.5 -1.8 -2.0 -2.2 -0.6 -1.2 1.1 1.1 1.5 1.3 -1.9 -1.2 -0.8 -1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 2.6 -1.0 0.3 0.2 1.0 -1.1 1.5 -0.2 0.1 -0.6 -1.3 0.1 0.6 -1.6 -0.6
Whole body water mass 0.0 0.2 0.9 -0.3 0.4 0.3 -0.0 0.2 -0.2 -1.0 -0.8 -0.5 -0.3 0.3 0.6 -0.8 0.0
Leg predicted mass (right) 0.0 0.1 0.8 -0.1 -0.2 -0.3 0.2 0.9 -0.2 -0.3 -0.2 0.3 0.2 -0.3 0.2 -0.4 -0.4
Arm fat mass (left) 0.0 0.2 0.8 -0.2 -0.1 -0.4 -0.9 0.3 -0.4 0.2 -0.1 -0.2 0.8 -0.3 0.6 -0.4 -0.5
Number of self-reported non-cancer illnesses 0.8 1.3 7.2 2.0 0.8 0.7 -0.5 1.0 0.7 -0.3 0.2 1.0 0.5 0.8 2.7 0.8 1.3
Average weekly champagne plus white wine intake 0.3 0.5 1.8 -1.2 -0.2 -0.1 -0.0 -1.3 -1.2 -0.1 -0.3 -0.6 -0.9 -0.3 -0.3 -0.4 -0.7
Miserableness 0.8 1.4 4.2 1.6 0.9 1.0 0.6 -0.3 1.2 -0.9 -0.2 -0.0 -0.8 1.2 2.1 1.8 1.7
Guilty feelings 0.6 0.9 4.2 1.5 -0.1 0.1 1.1 -0.2 1.4 0.1 0.7 0.8 0.3 0.2 1.3 2.1 0.6
Wears glasses or contact lenses 0.5 0.6 2.1 0.0 -0.5 -0.6 -1.3 0.4 1.4 0.8 0.4 1.5 0.7 -0.5 0.4 0.5 -0.6
Ever taken oral contraceptive pill 1.3 1.4 5.2 1.1 0.2 0.3 2.3 -0.6 1.8 1.3 0.9 1.1 1.1 0.5 0.4 1.6 1.3
Hearing aid user 0.4 0.5 2.3 -0.6 -0.0 -0.3 -0.6 -0.8 1.5 -0.8 0.0 0.5 0.6 -0.2 1.2 -0.3 -0.6
Mother’s age at death 0.4 0.5 1.4 -0.4 1.0 0.9 0.6 -0.2 0.5 -0.6 -1.2 -0.8 -1.0 0.8 0.1 -0.2 0.3
Financial situation satisfaction 0.5 0.6 1.1 -0.1 -0.6 -0.7 -1.0 0.5 -0.7 0.7 0.7 1.0 0.9 -0.7 -0.8 0.9 -1.0
Tinnitus: Yes, now most or all of the time 2.8 3.3 7.3 -2.5 -1.8 -1.9 -2.7 -1.9 -0.6 0.8 0.5 0.2 0.8 -2.0 -1.9 -2.4 -2.6
Commuting to job workplace: Public transport 0.7 0.8 3.5 -1.8 0.2 0.2 -0.8 -1.6 -0.1 -0.0 -0.0 -0.6 0.8 0.1 0.6 -1.9 -0.5
Eye problems/disorders: Glaucoma 0.1 0.2 0.7 -0.2 0.1 0.2 0.8 0.5 -0.3 -0.7 -0.0 0.0 0.8 0.1 0.3 -0.2 -0.0
Medication: Blood pressure 2.4 4.6 9.5 -3.1 -1.9 -1.8 -2.6 1.1 -2.7 1.1 1.7 1.8 2.2 -1.8 -1.4 -2.9 -2.7
Pain type(s) experienced in last month: Hip pain 0.3 0.3 2.3 0.3 0.1 0.1 0.5 0.1 0.4 0.1 -0.8 -0.0 -0.3 -0.1 -0.1 1.1 -1.5
Supplements: Fish oil (including cod liver oil) 0.3 0.5 2.1 -0.7 0.3 0.2 0.7 -0.2 -0.4 -0.6 -1.5 -0.9 -1.0 0.0 -0.2 -0.7 -0.4
High cholesterol (Self-reported) 1.6 2.8 4.9 -2.1 -2.0 -1.8 -2.1 -0.6 -1.5 0.7 2.1 0.9 0.9 -1.9 -1.2 -2.0 -2.2
Medication: Bendroflumethiazide 0.7 1.0 4.6 -0.5 1.0 0.9 -1.1 0.1 0.4 -1.5 -0.9 -0.7 -0.7 0.9 1.0 -2.1 0.7
Medication: Paracetamol 2.1 3.3 8.6 -0.9 1.7 1.4 -0.1 -2.9 1.0 -2.3 -2.9 -2.5 -1.6 1.2 2.1 -1.1 0.9
Medication: Lisinopril 0.3 0.4 1.5 -0.5 -0.0 -0.1 -1.2 -0.6 -0.5 -0.2 -0.5 -0.0 -0.4 -0.2 0.9 -1.1 -0.8
Medication: Atorvastatin 0.4 0.5 3.2 -0.4 -0.3 -0.2 -1.0 0.0 -1.8 0.2 0.5 0.0 1.1 -0.2 0.8 -0.3 -0.0
Illnesses of father: High blood pressure 0.7 0.8 2.2 0.2 1.2 0.9 -0.2 -1.0 0.9 -1.1 -1.4 -1.1 -1.5 0.8 0.5 -0.1 0.2
Alcohol drinker status: Never 1.3 1.6 6.2 -1.7 0.6 0.5 0.7 -1.7 -0.0 -0.6 -1.2 -2.5 -0.6 0.2 0.5 -2.5 -0.4
Ever smoked 0.2 0.4 2.6 0.3 0.1 0.1 -0.6 -0.7 1.0 0.1 -0.3 1.1 -0.1 -0.0 -0.3 1.6 0.3
Basal metabolic rate 0.0 0.2 0.8 -0.0 0.5 0.3 0.0 0.4 -0.1 -0.9 -0.7 -0.4 -0.2 0.3 0.9 -0.5 0.1
Leg fat percentage (left) 0.3 1.1 3.3 0.7 1.4 1.2 -1.1 0.3 1.0 -0.6 -1.3 -1.6 -0.2 1.2 1.8 -0.1 0.7
Arm fat-free mass (left) 0.1 0.6 2.0 -0.7 0.7 0.5 -0.3 -0.3 0.2 -1.0 -1.2 -1.1 -0.4 0.5 0.8 -1.4 -0.1
Number of operations (self-reported) 0.5 0.7 2.8 0.8 -0.2 -0.3 1.7 1.0 0.0 1.5 0.2 1.3 0.5 -0.3 0.3 1.0 0.0
Average weekly beer plus cider intake 0.3 0.4 1.7 1.3 -0.1 -0.0 -0.7 1.0 -0.2 0.2 0.3 -0.8 -1.1 -0.1 0.3 -0.2 1.0
Irritability 0.6 1.0 4.1 1.4 0.4 0.4 2.0 0.7 1.4 0.5 -0.3 -0.2 -0.8 0.2 0.8 1.9 0.2
Risk taking 1.5 2.2 5.3 0.9 -0.8 -0.8 1.9 2.2 1.5 1.7 1.4 2.3 1.3 -0.7 -0.2 2.3 0.1
Ever had prostate specific antigen (PSA) test 1.6 1.8 8.3 2.1 -0.3 -0.1 0.9 1.6 2.1 0.7 1.2 1.5 -0.3 0.0 -0.1 2.9 0.5
Fractured/broken bones in last 5 years 0.5 0.7 2.5 0.3 0.2 0.2 -0.3 -0.4 1.4 0.9 0.2 0.6 1.4 0.4 1.6 1.0 0.8
Age started oral contraceptive pill 1.9 2.4 10.2 -1.9 -1.1 -1.1 -1.9 0.1 -1.9 0.3 0.2 -0.9 -0.1 -1.2 -3.2 -2.4 -1.5
Diastolic blood pressure, automated reading 1.3 4.0 14.1 -1.3 2.0 1.7 -3.8 -1.2 0.2 -2.4 -2.4 -2.0 -1.2 1.5 2.2 -2.8 0.1
Ever depressed for a whole week 0.3 0.4 1.6 -0.2 0.1 -0.1 -0.2 0.7 0.3 0.2 -1.2 -1.1 -1.2 -0.3 -0.7 -0.2 -0.6
Unable to work because of sickness or disability 0.6 0.7 3.3 -0.9 -0.3 -0.6 -1.0 -0.2 1.0 0.2 -1.3 -0.6 -0.2 -0.8 -0.1 -1.1 -1.8
Commuting to job workplace: Cycle 0.6 0.7 2.0 -0.0 1.1 1.2 0.5 -1.0 0.5 -0.2 -1.1 -0.2 0.1 1.2 1.4 0.4 1.1
Myopia 2.3 3.3 13.0 -1.3 -1.7 -1.4 -0.0 0.5 -0.2 2.0 3.1 3.2 3.6 -1.2 0.6 0.4 -1.0
Vascular/heart problems diagnosed by doctor 0.4 1.1 5.0 0.9 0.5 0.4 2.2 -0.9 0.8 -0.4 -1.0 -1.0 -0.5 0.5 -1.0 2.0 0.4
Cholesterol lowering medication 2.1 3.1 10.0 -3.1 -0.9 -1.1 -2.4 -1.4 -0.8 0.7 0.4 -0.5 1.2 -1.3 0.1 -3.2 -2.9
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 2.0 -0.4 -0.5 -0.3 -1.4 -0.7 -0.0 0.9 1.0 -0.0 0.4 -0.3 -0.2 -0.7 -0.4
Pain experienced in last month 0.6 1.1 3.0 -1.2 -1.0 -1.0 0.2 -0.3 -0.3 1.5 1.2 0.8 1.4 -0.8 -0.7 -1.7 -0.6
Supplements: Calcium 0.5 0.5 2.3 -0.8 -0.5 -0.1 -0.9 -1.5 -0.5 -0.4 0.8 -1.0 0.3 -0.3 0.6 -0.7 -0.5
Basal cell carcinoma (self-reported) 0.5 0.6 1.5 -1.2 0.0 -0.2 -0.7 -0.6 -0.9 0.5 -0.7 -0.2 0.6 -0.1 -1.2 -1.1 -1.0
Heart attack/myocardial infarction (self-reported) 0.2 0.3 0.9 0.2 -0.7 -0.7 -0.8 -0.2 -0.9 0.1 0.1 -0.3 -0.5 -0.6 -0.6 -0.8 -0.5
Deep venous thrombosis (DVT) (self-reported) 1.0 1.3 4.6 -0.8 -0.8 -0.8 -1.2 0.4 -1.4 -0.9 -0.3 0.1 -2.1 -1.1 -2.1 0.3 -1.4
Heart disease (siblings) 0.6 0.7 3.9 0.0 -0.3 -0.4 -1.3 -2.0 -0.5 0.0 -0.8 -1.0 -0.7 -0.4 -0.1 -0.9 -1.0
Alcohol drinker status: Previous 0.9 1.0 3.5 1.3 1.0 1.0 -1.2 0.4 0.1 -1.9 -0.6 -0.6 -1.8 1.0 0.5 0.7 0.6
Pack years of smoking 0.3 0.4 1.3 0.2 0.7 0.7 -1.1 -0.1 -0.4 -1.1 -0.5 -0.8 0.2 0.9 -0.1 -0.6 0.1
Impedance of whole body 0.1 0.7 2.4 0.5 -0.1 -0.0 -0.4 0.1 -0.7 0.2 1.3 1.5 1.1 0.0 0.9 1.5 0.6
Leg fat mass (left) 0.1 0.5 1.9 -0.0 0.7 0.4 -0.8 0.3 0.4 -0.4 -1.0 -1.0 0.4 0.5 1.4 -0.5 0.1
Arm predicted mass (left) 0.1 0.6 2.0 -0.8 0.7 0.5 -0.5 -0.4 0.3 -1.0 -1.3 -1.2 -0.4 0.5 0.8 -1.4 -0.3