Hub : Genes

ARHGAP22

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1950	0.0480	2.2e-07	0.030	0.088	0.114	0.114	0.107	1.2e-04	8.4e-11	1.1e-13	1.0e-13	6.1e-13
2	GTEx	Artery Aorta	0.1800	0.0610	2.6e-03	0.165	NA	0.151	NA	0.164	2.1e-09	NA	1.1e-08	NA	2.4e-09
3	GTEx	Artery Tibial	0.2485	0.0535	8.1e-06	0.208	NA	0.197	NA	0.118	3.3e-16	NA	2.2e-15	NA	1.6e-09
4	GTEx	Colon Sigmoid	0.2460	0.0730	7.0e-04	0.017	NA	0.031	NA	0.022	8.2e-02	NA	2.9e-02	NA	5.6e-02
5	GTEx	Colon Transverse	0.1920	0.0640	2.3e-03	-0.001	NA	0.041	NA	0.007	3.6e-01	NA	4.8e-03	NA	1.4e-01
6	GTEx	Pancreas	0.2080	0.0830	6.1e-03	-0.005	NA	0.002	NA	-0.002	5.8e-01	NA	2.6e-01	NA	4.2e-01
7	GTEx	Whole Blood	0.1240	0.0470	5.3e-03	0.089	NA	0.106	NA	0.083	1.5e-08	NA	5.8e-10	NA	4.3e-08
8	METSIM	Adipose	0.1504	0.0425	9.9e-06	0.065	0.060	0.085	0.075	0.072	5.7e-10	2.7e-09	9.4e-13	2.1e-11	6.2e-11
9	NTR	Blood	0.0241	0.0097	1.1e-03	0.011	0.012	0.016	0.013	0.017	1.2e-04	5.8e-05	4.0e-06	3.2e-05	2.2e-06
10	YFS	Blood	0.2742	0.0410	0.0e+00	0.071	0.125	0.151	0.158	0.138	4.3e-22	1.0e-38	4.2e-47	2.7e-49	1.1e-42
11	TCGA	Breast Invasive Carcinoma	0.1308	0.0288	2.3e-15	0.098	0.095	0.103	NA	0.097	1.7e-19	9.2e-19	2.4e-20	NA	3.4e-19
12	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1770	0.0610	1.4e-03	0.069	0.071	0.088	NA	0.129	8.6e-05	6.8e-05	9.7e-06	NA	8.0e-08
13	TCGA	Brain Lower Grade Glioma	0.1145	0.0373	3.2e-06	0.032	0.043	0.052	NA	0.048	1.3e-04	1.0e-05	1.5e-06	NA	3.3e-06
14	TCGA	Lung Adenocarcinoma	0.1048	0.0344	1.8e-05	0.053	0.027	0.054	NA	0.052	7.3e-07	3.9e-04	6.1e-07	NA	1.1e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.7	1.2	5.1	-2.1	-0.8	-0.6	-0.6	-0.2	0.5	1.5	0.7	-0.4	0.8	-0.7	0.8	-2.3	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.4	-0.4	-0.4	-0.3	-0.9	1.1	-0.2	0.9	0.1	-0.9	-0.2	-0.3	0.4	-1.2	-0.1
Depressed Affect (Nagel 2018)	1.0	2.1	4.1	1.8	1.6	1.6	0.0	-1.2	2.0	-1.6	-1.0	-0.5	-1.4	1.9	1.4	1.7	1.4
Depression (Nagel 2018)	0.2	0.4	0.7	-0.9	0.5	0.4	0.2	-0.5	0.4	-0.8	-0.5	-0.7	-0.6	0.4	0.8	-0.8	-0.6
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.7	1.3	-0.6	-0.4	-0.5	1.7	-0.7	1.6	1.5	1.2	1.1	-0.3	0.7	0.4	0.5
Neuroticism (Nagel 2018)	0.5	1.1	2.5	1.6	0.9	1.0	-0.3	-0.8	1.4	-1.5	-0.8	-0.5	-1.4	1.0	1.0	1.2	0.8
Schizophrenia (2018)	0.2	0.5	2.5	1.2	0.1	0.1	-0.7	1.6	-0.7	0.0	-0.4	-0.8	-0.9	0.1	-0.2	0.4	0.3
Schizophrenia vs Biploar Disorder	0.3	0.3	1.0	0.9	-0.1	-0.1	-0.2	-0.9	-0.2	-1.0	-0.4	-0.4	-0.8	-0.1	-0.2	0.9	-0.1
Worry (Nagel 2018)	0.4	0.7	3.2	1.2	0.3	0.4	-1.5	-0.0	0.6	-1.5	-0.6	0.0	-1.8	0.3	-0.1	0.5	0.1
Alzheimer’s Disease (in mother)	1.4	1.7	4.0	1.3	1.4	1.7	0.5	0.7	0.7	-2.0	-0.8	0.0	-1.6	1.7	0.8	1.1	2.0
Alzheimer’s Disease (in father)	0.6	0.7	3.2	0.8	0.6	0.6	0.6	1.3	1.8	0.2	-0.2	-0.2	-0.1	0.9	0.8	0.4	1.0
Alzheimer’s Disease (including proxy)	2.3	3.3	7.7	2.0	2.1	2.3	0.4	1.3	1.6	-2.0	-1.5	-0.4	-1.7	2.5	1.6	1.5	2.8
Crohns Disease (2017)	1.5	3.2	13.1	3.6	1.2	1.1	2.0	2.1	2.3	0.1	-1.2	0.1	-0.6	1.5	0.6	2.7	1.9
Irritable Bowel Disease (IBD)	0.9	2.1	7.5	2.7	0.2	0.2	2.6	2.1	1.9	0.6	-0.8	-0.6	-0.9	0.5	-0.6	1.6	1.1
Ulcerative Colitis (UC)	0.6	1.2	4.4	0.8	-1.3	-1.3	2.0	1.2	0.3	1.2	0.2	-0.5	-0.2	-1.0	-2.1	0.2	-0.4
Major Depression (MDD)	0.7	0.9	3.8	-1.5	0.1	-0.1	-0.3	0.2	-0.1	-0.3	-0.9	-1.5	-0.8	-0.3	0.8	-2.0	-1.1
Reaction Time	0.9	1.8	6.2	0.5	-0.2	-0.1	1.0	0.1	0.3	1.4	1.7	2.5	2.4	0.0	0.8	2.3	0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	6.6	0.8	1.3	1.4	-0.2	2.6	-0.5	0.4	-0.1	0.6	0.5	1.3	1.7	-0.3	1.9
Breast Cancer	0.6	1.4	6.8	1.4	1.0	1.1	0.6	2.6	-0.6	-0.0	-0.6	0.2	0.2	1.3	-1.1	1.4	1.6
Ovarian Cancer	1.1	1.4	4.8	-0.2	-1.9	-1.8	0.3	-0.3	-1.1	1.0	1.1	0.1	-0.5	-1.8	-2.2	-0.1	-1.1
Prostate Cancer	0.2	0.3	0.8	0.3	0.3	0.2	-0.6	-0.1	-0.9	-0.4	-0.8	-0.5	0.8	0.0	0.5	0.6	0.3
Age at First Birth	1.1	1.6	5.0	-0.3	1.2	1.4	0.5	-2.2	0.9	-1.1	-0.2	-1.3	-0.5	1.4	1.7	-0.9	1.9
Bipolar Disorder (2011)	1.1	1.1	5.3	-0.3	-1.2	-1.2	-0.7	-0.0	0.3	2.3	1.2	0.9	1.5	-1.2	0.0	0.0	-0.6
Body Mass Index (BMI) (2010)	0.4	0.6	3.0	-0.7	-0.1	-0.1	-1.7	-0.9	-1.3	0.3	0.0	-0.7	-0.4	-0.4	-0.3	-0.6	-0.8
Coronary Artery Disease (CAD)	4.6	5.4	13.1	-0.8	-3.2	-3.0	1.3	1.2	-1.2	2.2	3.6	2.8	1.7	-3.0	-2.8	-0.1	-2.5
Crohns Disease (2012)	2.4	3.9	10.8	3.3	2.1	2.0	1.2	0.7	2.5	-2.2	-2.2	-1.0	-2.2	2.2	1.0	1.2	1.9
Mean Putamen Volume	1.6	1.8	8.7	-1.0	-0.1	-0.3	-3.0	-1.8	-0.1	-1.3	-1.4	-2.1	-0.9	-0.5	-0.4	-1.8	-0.5
Fasting Glucose	1.0	1.2	2.5	0.7	1.3	1.4	1.2	0.0	1.2	-0.4	-0.3	-0.5	-1.1	1.6	1.6	-0.1	1.5
HbA1C	0.9	1.1	4.0	0.1	0.8	1.0	0.0	-1.1	-1.1	-1.2	-0.6	-1.9	-2.0	0.8	0.0	-0.1	0.7
HDL Cholesterol	0.2	0.4	1.9	-1.4	-0.3	-0.4	-0.2	0.7	-0.1	0.7	-0.5	0.4	0.2	-0.5	-1.1	-0.2	-0.2
LDL Cholesterol	1.7	2.6	5.2	1.1	2.1	2.0	-0.5	0.4	0.3	-1.5	-2.3	-2.0	-2.2	1.9	2.2	1.0	0.9
Lupus	0.2	0.3	2.1	0.7	0.2	0.2	-0.3	-1.5	0.4	-0.4	-0.1	0.3	0.2	0.4	-0.5	-0.2	0.0
Neuroticism (2016)	0.8	1.2	6.9	1.7	0.9	0.6	0.6	0.2	2.6	0.1	-0.1	-0.0	-0.1	0.8	2.1	0.4	0.6
Primary Biliary Cirrhosis	1.5	2.2	5.5	1.6	1.7	1.6	0.7	-0.6	1.0	-1.2	-2.0	-2.3	-1.9	1.7	0.9	-0.2	1.8
Rheumatoid Arthritis	1.7	2.3	5.8	2.0	1.6	1.5	-0.9	-0.9	1.9	-2.4	-1.6	-0.2	-2.0	1.4	1.0	0.8	1.7
Schizophrenia (2014)	0.2	0.4	1.7	0.9	0.4	0.3	-0.5	1.2	-0.2	-0.2	-0.7	-0.9	-1.3	0.4	0.2	0.1	0.1
Triglycerides	1.5	2.4	6.5	1.3	2.3	2.1	0.6	-0.3	1.7	-1.9	-1.1	-0.4	-1.0	2.0	2.5	1.4	1.2
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.7	1.0	1.7	1.8	0.9	0.1	1.9	-1.5	-1.0	-0.6	-1.1	1.7	1.8	0.7	1.5
Ulcerative Colitis	0.6	0.9	3.3	1.8	-0.5	-0.4	1.5	0.9	1.6	0.2	0.3	-0.1	-0.7	-0.2	-1.2	0.9	-0.0
Blood Eosinophil Count	0.4	3.2	6.0	0.9	2.3	2.3	-2.1	1.0	-2.2	-2.1	-1.2	-1.8	-0.6	2.4	2.4	-0.2	1.5
Blood Platelet Count	0.9	9.9	66.3	-2.8	-1.1	-1.2	-8.1	-1.2	-6.5	0.1	0.3	0.4	1.3	-1.6	-0.0	-2.5	-2.6
Blood Red Count	0.3	3.3	15.0	-2.2	0.1	0.3	-2.3	-1.4	-0.1	-2.0	-0.5	-3.0	-2.3	0.0	-0.5	-3.9	-0.6
Blood White Count	1.0	7.4	46.6	-2.1	1.5	1.2	-6.8	0.5	-4.3	-3.3	-2.2	-1.7	-1.6	0.8	1.0	-2.7	-0.8
Heel T-Score	0.4	3.5	13.0	-2.0	-1.5	-1.4	-3.6	0.1	-3.0	0.1	0.6	-0.7	-0.7	-1.5	-1.7	-2.8	-2.1
BMI	0.1	0.6	2.2	-0.3	-0.3	-0.6	-1.5	-0.5	1.0	-0.6	-0.4	-0.8	-0.4	-0.6	0.2	-0.8	-1.3
Height	0.1	2.0	8.5	-1.0	-0.6	-0.8	-1.4	0.8	-1.6	-0.7	1.8	2.6	2.9	-0.4	1.0	-0.0	-0.8
Waist Hip Ratio (WHR)	0.4	1.7	4.5	-1.1	1.2	1.2	-2.1	-1.0	-1.8	-2.1	-1.1	-1.3	-0.7	1.1	0.7	-0.8	0.9
Systolic Blood Pressure	1.0	5.3	18.7	-3.1	-1.4	-1.7	-4.3	-1.9	-2.6	-0.7	0.0	-0.7	0.0	-2.0	-0.8	-4.0	-2.9
Smoking Status	0.2	0.4	1.6	0.3	0.5	0.3	-1.2	-0.4	0.4	-0.6	-1.2	0.4	-0.5	0.3	-0.7	0.2	0.4
Allergy or Eczema	1.8	4.8	13.7	2.5	2.6	2.6	1.8	1.4	2.2	-0.7	-1.4	0.2	-0.5	2.5	3.7	2.9	2.7
Cardiovascular Disease	0.4	1.4	7.5	-1.0	-0.7	-0.7	-2.3	1.0	-1.3	-0.3	1.3	0.3	0.1	-0.7	0.0	-2.7	-0.3
Hypothyroidism (self reported)	0.6	1.4	4.9	-1.5	-1.1	-1.2	0.8	-2.2	0.4	1.2	0.6	1.3	1.4	-1.3	-0.7	-0.3	-1.0
Respiratory disease	0.2	0.5	2.5	0.6	0.3	0.0	0.4	-0.7	1.4	0.2	-0.5	0.5	0.5	0.0	1.1	1.6	-0.2
Type 2 Diabetes (T2D) (2018)	1.0	1.8	5.8	-1.3	0.6	0.7	-2.4	-1.4	-1.6	-2.0	-0.3	-0.8	-0.6	0.6	1.6	-2.0	0.4
Lung FEV1/FVC ratio	0.1	0.4	2.4	0.1	-0.4	-0.3	-0.4	1.6	0.8	0.1	-0.1	-0.1	-1.3	-0.5	-0.4	-0.1	-0.6
Lung FVC	0.2	1.2	3.1	-0.8	1.2	1.0	-0.9	-1.7	1.0	-0.3	-1.2	-1.6	-0.5	0.9	0.6	-1.8	0.3
Neuroticism	0.3	0.8	2.7	1.6	0.4	0.7	-0.5	-0.1	0.3	-1.3	0.5	0.5	-1.0	0.8	0.8	1.3	0.9
Chronotype (morning person)	0.1	0.3	1.1	-0.5	-0.4	-0.4	0.7	0.5	0.5	1.0	0.3	0.4	0.9	-0.4	0.2	0.5	-0.6
Hair Pigment	0.0	0.9	2.5	0.6	1.0	0.8	-0.2	-0.5	0.5	-1.6	-1.5	-1.2	-1.5	0.6	0.9	0.2	0.3
Tanning	0.1	0.7	1.8	-0.0	1.1	1.0	-1.1	0.7	0.9	-0.4	-1.3	-1.3	-0.6	1.0	-0.1	-1.0	0.2
Hand grip strength (left)	0.1	0.3	1.2	-0.6	-0.3	-0.4	0.2	-0.1	0.6	-0.5	-0.1	-0.6	-0.6	-0.3	-0.7	-1.1	-0.3
Number of treatments/medications taken	0.4	0.8	4.9	0.7	0.9	0.8	-1.1	1.0	-0.5	-0.6	-0.6	-0.4	0.2	0.9	2.2	-0.1	0.5
Average weekly spirits intake	1.7	2.2	6.9	2.6	1.1	0.8	0.6	1.1	2.5	0.7	-0.4	1.0	0.5	1.1	1.8	2.4	1.1
Sensitivity / hurt feelings	0.3	0.6	3.3	1.1	-0.9	-0.7	0.6	0.0	0.3	0.3	0.6	0.3	-0.8	-0.7	0.1	1.8	-0.5
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.7	-0.4	-0.9	-1.0	0.9	0.4	0.3	1.0	1.1	1.3	1.1	-1.0	0.3	0.2	-0.9
Hearing difficulty/problems: Yes	0.5	0.8	2.1	0.9	0.9	0.7	-0.3	-1.0	1.4	-0.7	-1.3	-0.4	-0.4	0.7	0.7	1.5	0.0
Relative age of first facial hair	0.3	0.5	2.2	0.8	-0.7	-0.3	0.4	0.3	0.8	-0.2	0.9	0.2	-1.5	-0.5	-1.0	1.0	-0.0
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.3	1.1	1.5	1.3	2.1	0.9	1.2	-0.4	-1.7	-0.3	-0.1	1.2	1.6	0.5	0.8
Ever used hormone-replacement therapy (HRT)	3.3	4.2	9.4	-3.1	-2.4	-2.4	-2.3	-0.8	-1.0	0.9	1.3	0.2	-0.1	-2.5	-3.0	-2.4	-2.6
Ever had hysterectomy (womb removed)	0.5	0.6	2.1	-1.1	-0.4	-0.5	-1.0	0.3	-0.9	0.6	0.2	0.4	0.6	-0.5	-1.5	-1.0	-0.8
Systolic blood pressure, automated reading	2.0	5.9	20.8	-3.5	-1.7	-2.1	-4.6	-1.2	-1.3	1.0	0.3	-0.3	0.8	-2.5	-1.3	-4.0	-3.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.2	-0.0	0.7	0.6	1.0	0.1	0.0	-1.1	-1.5	-0.6	-0.5	0.5	0.1	-0.1	-0.1
Angina	0.9	1.1	4.8	0.8	1.0	0.9	0.1	-0.4	0.8	-0.6	-2.2	-1.7	-1.9	0.7	0.4	0.1	0.3
Medication for hormone replacement therapy	1.3	1.4	3.3	-0.6	-1.3	-1.4	1.2	-1.3	1.7	0.5	0.2	-0.7	-1.0	-1.4	-1.7	-0.4	-1.8
Vitamin and mineral supplements	0.2	0.2	0.8	0.6	0.2	-0.1	-0.9	0.7	0.5	0.5	-0.3	0.6	0.5	0.1	0.2	0.3	-0.4
Supplements: Zinc	1.6	1.7	3.3	-1.1	-1.8	-1.5	0.5	-0.8	-1.3	1.3	1.8	1.0	1.5	-1.6	-1.3	-0.6	-1.3
Medication: Co-codamol	0.7	0.9	2.4	-1.0	0.9	0.7	-0.6	-1.5	0.3	-1.5	-1.1	-0.9	-0.7	0.6	0.6	-1.1	0.2
Medication: Metformin	1.0	1.4	3.7	0.5	1.3	1.3	-0.6	0.9	-0.9	-1.8	-1.2	-1.2	-1.0	1.2	1.9	-0.7	0.7
Diabetes (father)	0.2	0.2	0.8	-0.3	-0.0	0.0	0.9	0.2	-0.3	0.5	0.4	-0.9	-0.2	0.1	0.3	-0.8	0.2
Diabetes (mother)	0.6	0.7	4.4	0.5	0.5	0.2	-0.2	0.1	2.1	0.2	-0.5	1.2	1.1	0.4	0.7	1.1	0.6
Severe depression (siblings)	1.8	2.0	5.3	-2.2	-0.1	0.1	-1.8	-2.3	-1.6	-1.0	-0.3	-2.1	-0.5	-0.0	-0.2	-2.1	-0.9
Pack years adult smoking proportion	0.2	0.3	1.3	0.0	0.4	0.5	-0.8	-0.2	-0.2	-1.1	-0.5	-0.9	0.0	0.6	-0.2	-0.5	-0.1
Impedance of leg (right)	0.1	0.6	2.3	0.2	0.8	0.9	-0.4	-1.1	-0.0	-0.5	0.3	-0.5	0.2	1.0	1.5	0.4	1.1
Leg fat-free mass (left)	0.0	0.1	0.3	-0.2	-0.1	-0.2	0.2	0.5	-0.3	-0.6	-0.2	0.2	0.2	-0.1	0.5	-0.5	-0.3
Trunk fat percentage	0.1	0.4	2.0	0.1	0.2	-0.0	-1.4	0.5	-0.1	0.0	0.0	0.5	1.2	0.0	1.2	-0.1	-0.1
Hand grip strength (right)	0.3	0.9	2.8	-1.7	-1.0	-0.9	0.8	-0.9	-0.9	-0.2	0.5	-0.8	-0.4	-1.0	-1.1	-1.2	-1.0
Townsend deprivation index at recruitment	1.3	1.8	5.7	-0.8	-1.6	-1.6	-2.4	0.6	-1.7	0.2	0.7	0.3	0.5	-1.7	-0.9	-1.3	-2.2
Current tobacco smoking	0.8	1.3	3.6	-1.2	-1.3	-1.5	-1.9	-0.7	-0.8	0.7	0.9	1.1	0.9	-1.4	-1.0	-0.6	-1.1
Average weekly fortified wine intake	0.4	0.5	1.8	0.4	-0.4	-0.3	0.3	1.2	0.2	0.5	0.7	1.1	1.0	-0.3	-0.4	1.3	-0.3
Maternal smoking around birth	0.5	0.7	2.5	1.6	0.7	0.6	1.0	0.9	0.8	0.4	-0.2	0.8	0.2	0.8	0.9	1.2	0.9
Fed-up feelings	0.2	0.4	2.8	0.3	0.3	0.4	1.0	-0.6	0.7	-0.6	-0.0	0.6	-0.0	0.4	0.4	1.7	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.1	-0.4	-0.7	-0.8	0.2	0.2	0.1	0.0	0.5	0.9	0.5	-0.7	0.1	-0.2	-1.1
Relative age voice broke	1.5	2.3	10.1	-0.2	-2.2	-1.8	0.1	0.0	-0.2	1.3	3.2	2.2	0.5	-1.8	-1.8	0.8	-1.1
Taking other prescription medications	1.0	1.6	4.8	2.1	-0.1	-0.2	1.1	2.2	0.7	1.5	1.0	1.5	1.2	0.1	0.9	1.8	0.5
Age when periods started (menarche)	0.6	1.5	5.0	-1.3	-1.3	-1.0	0.2	-1.0	-0.3	1.1	2.2	0.5	1.7	-0.7	-1.1	-1.9	-0.8
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	5.6	-1.4	-1.9	-1.8	-0.8	0.0	-1.4	0.8	0.8	-0.1	-0.5	-2.0	-2.4	-1.5	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.9	0.5	0.0	0.0	-1.7	0.0	-1.4	-0.2	0.9	-0.0	0.7	0.3	1.1	-0.7	0.0
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.8	0.1	-0.6	-0.4	0.6	1.9	-0.5	0.9	1.6	1.9	1.4	-0.2	0.1	0.8	0.3
Qualifications: CSEs or equivalent	0.9	1.2	2.2	-1.3	-1.3	-1.4	-0.4	-0.7	-0.7	1.0	1.3	0.4	1.5	-1.5	-1.1	-0.5	-1.1
Serious illness, injury or assault to yourself	0.5	0.7	2.7	0.2	0.3	0.0	1.6	0.4	1.4	0.3	-0.8	-0.2	0.1	-0.1	1.6	0.6	-0.7
High blood pressure	0.3	0.9	3.5	-0.6	-0.2	-0.1	-1.9	1.3	-0.6	0.5	0.9	1.0	0.3	-0.2	1.1	-1.8	0.1
Hayfever, allergic rhinitis or eczema	2.2	4.8	17.6	1.9	2.7	2.7	2.2	0.7	1.8	-0.7	-1.5	0.3	0.1	2.7	4.2	2.3	2.6
Multivitamins +/- minerals	0.3	0.3	1.3	-0.4	-0.6	-0.5	1.1	-0.4	-0.2	-0.1	0.2	-0.4	-0.7	-0.5	-1.0	-0.5	-0.2
Stomach or abdominal pain in last month	1.0	1.2	2.8	-1.4	-1.3	-1.3	-1.3	-0.8	0.4	0.8	0.8	-0.1	0.8	-1.3	-0.5	-1.7	-1.5
Supplements: Glucosamine	0.4	0.5	3.0	-0.2	-0.3	-0.5	-0.8	1.7	-0.2	0.4	-0.1	0.9	0.2	-0.6	-0.4	0.7	-0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.0	-1.4	-0.3	-0.4	-0.6	-1.1	-1.1	-0.5	-0.2	-1.0	-0.5	-0.5	0.0	-1.7	-0.7
Medication: Atenolol	0.7	0.8	2.9	0.3	1.2	1.1	-1.2	-0.1	-0.8	-0.7	-1.2	-0.4	0.3	1.0	1.7	-0.7	0.7
Medication: Levothyroxine sodium	0.3	0.6	3.3	-0.7	-0.5	-0.5	0.3	-1.8	0.9	0.5	0.6	0.6	0.3	-0.6	-0.9	-0.6	-0.4
Sitting height	0.2	1.7	5.3	-0.7	-1.9	-1.7	-1.1	-0.1	1.1	0.1	2.3	2.0	0.6	-1.7	-0.9	-0.2	-1.3
Chronic bronchitis/emphysema (father)	0.8	1.0	6.5	0.2	0.5	0.6	-0.2	2.5	-2.2	-0.4	0.2	0.8	-0.2	0.6	-0.3	0.4	0.3
High blood pressure (mother)	1.1	1.5	3.6	0.5	1.6	1.4	-0.8	0.1	-0.1	-1.6	-1.9	-1.8	-1.8	1.3	1.2	-0.4	0.7
Body mass index (BMI)	0.0	0.2	0.6	0.0	0.3	0.1	-0.4	0.4	0.6	0.1	-0.8	-0.6	0.1	0.1	0.8	-0.4	-0.4
Impedance of leg (left)	0.1	0.5	2.2	0.2	0.9	0.9	-0.2	-0.6	0.3	-0.1	0.1	-0.5	0.3	0.9	1.5	0.5	1.0
Leg predicted mass (left)	0.0	0.1	0.4	-0.1	-0.0	-0.2	0.1	0.5	-0.3	-0.6	-0.3	0.1	0.1	-0.1	0.5	-0.5	-0.3
Trunk fat mass	0.1	0.4	2.0	0.1	0.5	0.2	-1.4	0.5	-0.0	-0.5	-0.4	0.1	0.8	0.3	1.4	-0.2	0.1
Waist circumference	0.2	0.6	3.1	0.2	0.8	0.6	-1.8	0.4	-0.1	-0.9	-0.6	-0.3	0.1	0.7	1.5	0.0	0.2
Number of incorrect matches in round	0.3	0.5	1.9	0.1	-1.0	-0.9	-1.0	0.6	0.4	0.1	1.4	0.6	0.2	-0.8	-0.5	-0.3	-0.5
Past tobacco smoking	0.3	0.5	2.7	-0.7	-0.7	-0.7	0.7	0.5	-0.3	0.4	0.9	-0.5	0.4	-0.6	0.2	-1.6	-0.8
Alcohol usually taken with meals	0.3	0.5	1.5	-1.0	-0.6	-0.5	-0.3	-1.2	-0.2	-0.2	-0.4	-0.8	-0.5	-0.7	-0.9	-0.8	-0.4
Nervous feelings	0.6	1.2	2.8	1.7	0.8	0.8	-1.1	0.9	1.1	-0.9	-0.7	-0.0	-1.5	0.7	1.6	0.9	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.1	-1.0	0.3	0.1	-0.1	-0.7	0.8	-1.1	-0.7	-0.1	-0.7	0.1	0.1	-1.0	-0.0
Hearing difficulty/problems with background noise	0.5	0.8	3.3	0.9	0.8	0.8	0.8	0.1	1.5	-0.5	-1.0	-0.7	-1.8	0.6	0.1	1.0	0.5
Hair/balding pattern: Pattern 2	0.3	0.4	1.4	0.5	0.7	0.8	-0.1	0.4	-0.5	-1.2	0.2	-0.5	-0.7	0.7	1.0	0.5	0.6
Had menopause	2.2	2.8	6.9	-1.8	-1.7	-1.8	-2.1	0.2	-1.8	1.5	1.1	1.4	1.9	-1.6	-2.6	-1.1	-1.5
Had other major operations	0.5	0.6	2.0	-0.2	-0.5	-0.4	0.1	1.4	-0.9	1.1	1.0	1.1	0.7	-0.4	0.5	-0.5	-0.4
Forced vital capacity (FVC)	0.1	0.3	1.6	-0.9	0.3	0.1	-0.6	-0.8	-0.1	-0.6	-0.2	-0.3	-0.2	0.1	0.7	-1.3	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	3.5	0.8	0.6	0.6	-1.9	-0.6	-1.6	-1.1	0.4	-0.1	0.4	0.8	1.1	0.2	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.2	-0.3	-0.8	-0.9	-0.7	-0.0	0.3	1.0	0.1	0.0	0.3	-1.0	-0.6	0.0	-1.1
Qualifications: None of the above	0.9	2.0	10.3	-0.1	1.1	1.1	-3.2	-0.9	0.2	-2.1	-1.5	-1.6	-1.2	1.0	0.7	-1.1	1.1
Financial difficulties in last 2 years	1.0	1.3	3.4	1.7	1.1	1.1	1.8	1.2	0.5	-0.9	-0.8	-0.6	-1.2	1.1	0.9	1.4	1.2
Mouth/teeth dental problems	0.6	0.9	7.4	-0.0	-0.3	-0.4	-2.7	1.0	-1.5	0.1	0.2	-0.0	-0.9	-0.4	-0.2	-0.4	-0.6
Heart attack	0.3	0.3	1.4	0.4	-0.6	-0.6	-0.9	0.2	-1.2	0.1	0.1	-0.2	-0.5	-0.5	-0.6	-0.6	-0.5
Allergy	1.0	2.2	8.8	-1.2	-1.7	-1.6	-1.5	-0.3	-1.1	0.9	1.2	0.1	0.5	-1.6	-3.0	-2.0	-1.8
Pain all over the body in last month	0.3	0.4	1.1	0.9	0.6	0.5	0.8	-0.3	0.3	-0.8	-1.1	-0.4	-0.7	0.6	0.3	0.5	0.1
Diabetes (self-reported)	0.4	0.6	1.9	-1.2	-0.1	0.0	-0.4	-0.4	-1.3	-0.4	0.8	0.6	0.9	-0.1	1.1	-1.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.3	-1.3	-0.1	0.2	0.1	-0.1	-0.0	0.2	0.6	0.7	0.3	-0.2	1.5	-0.5	-0.9
Medication: Ramipril	1.0	1.3	3.2	1.2	0.4	0.3	-1.3	1.8	-0.5	0.5	1.1	1.6	1.8	0.7	1.4	0.0	1.3
Medication: Simvastatin	0.3	0.4	2.0	-0.1	-0.3	-0.4	-1.4	-0.3	-0.3	0.5	0.4	0.4	0.8	-0.3	0.7	-0.6	-0.8
Fluid intelligence score	2.6	5.4	14.1	2.8	2.7	3.0	1.3	3.0	-0.0	-0.4	-0.8	0.6	0.1	3.0	3.8	1.8	3.7
Illnesses of siblings	2.5	3.5	11.4	-1.2	-2.0	-1.5	2.1	2.2	-1.0	1.8	3.4	2.3	2.5	-1.6	-0.9	-0.1	-0.5
Neuroticism score	0.6	1.3	6.1	2.3	0.6	0.7	0.2	0.7	0.8	-0.4	0.1	0.6	-0.6	0.8	1.3	2.5	1.0
Weight	0.1	0.3	1.8	0.1	0.4	0.3	-0.6	0.6	-0.0	-0.6	-0.5	-0.1	0.2	0.3	1.3	-0.3	-0.1
Impedance of arm (right)	0.4	1.7	5.3	1.0	-0.7	-0.4	-0.6	0.4	-2.0	0.0	2.1	2.3	1.4	-0.3	0.5	2.0	0.9
Arm fat percentage (right)	0.0	0.1	0.6	0.4	0.1	-0.1	-0.7	0.4	-0.1	0.1	-0.2	-0.1	0.7	-0.1	0.7	0.2	0.0
Trunk fat-free mass	0.1	0.4	1.5	-0.1	0.6	0.6	0.1	-0.0	-0.2	-1.2	-0.9	-0.8	-0.7	0.6	0.8	-0.7	0.3
Hip circumference	0.1	0.3	1.5	0.6	0.5	0.5	-0.4	0.4	0.5	-0.5	-0.3	-0.2	0.1	0.5	1.2	0.2	0.3
Time employed in main current job	0.7	0.8	3.5	0.7	1.2	1.1	1.9	0.3	0.0	0.8	0.2	0.3	0.7	1.3	0.5	-0.2	1.3
Alcohol intake versus 10 years previously	0.3	0.5	3.8	0.3	0.3	0.3	-0.1	-0.6	-0.1	-0.6	-0.7	-1.0	-2.0	0.0	-0.1	0.6	-0.2
Father’s age at death	0.2	0.3	1.7	-0.3	0.4	0.4	-0.5	-1.3	0.4	-0.6	-0.6	-0.4	-0.6	0.3	0.3	-0.6	-0.0
Worrier / anxious feelings	0.5	1.0	4.0	1.4	0.2	0.5	-0.6	2.0	-0.6	-0.9	0.7	0.8	-0.3	0.5	1.5	1.3	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	0.7	1.2	1.0	1.0	0.4	-0.1	-0.9	-1.4	-0.2	-0.3	1.1	1.2	0.8	0.9
Falls in the last year	3.8	5.1	8.2	2.1	2.7	2.9	1.4	-0.3	1.0	-2.7	-2.9	-2.5	-2.8	2.8	2.3	1.0	2.2
Hair/balding pattern: Pattern 3	1.3	2.0	5.3	-2.3	-1.4	-1.5	-0.0	-1.2	-0.5	1.9	0.5	0.5	0.9	-1.6	-1.9	-1.3	-1.8
Number of live births	0.6	0.9	1.5	-0.9	-1.2	-1.1	-0.9	-1.1	0.4	0.9	1.2	0.9	0.6	-1.1	-0.8	0.7	-0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.8	-1.0	0.2	0.0	-0.5	-0.2	0.2	-0.5	0.0	-0.3	-0.7	-0.0	0.8	-1.4	-0.1
Pulse rate	0.9	1.5	8.2	-0.6	-1.0	-0.9	1.2	0.2	2.9	1.6	0.8	-0.6	0.0	-0.9	-1.0	-1.4	-1.0
Happiness	0.5	0.6	2.4	0.1	-0.4	-0.5	-1.6	0.4	-0.3	0.6	0.7	1.2	1.1	-0.4	0.5	0.9	0.4
Noisy workplace	0.6	0.8	4.0	0.3	0.7	0.6	-0.1	-2.0	0.8	0.0	-1.2	-1.8	-0.1	0.5	0.2	-0.1	-0.0
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.6	-1.0	0.4	0.5	0.6	-0.8	0.6	0.9	0.4	0.4	1.3	0.6	0.8	-1.0	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.4	0.1	-0.1	0.0	1.2	-1.5	1.2	0.4	0.0	-1.0	0.3	0.1	-0.1	-0.8	0.8
Mouth/teeth dental problems: Dentures	0.1	0.3	1.3	-0.3	-0.1	0.1	1.1	0.4	0.1	-0.1	0.5	-0.4	-0.5	0.1	-0.7	-0.6	0.6
Asthma	0.1	0.2	0.8	-0.1	-0.2	-0.3	0.0	-0.9	0.5	-0.0	-0.5	-0.6	-0.2	-0.3	0.4	0.4	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	5.5	0.2	1.3	1.2	0.9	-1.0	1.0	-0.6	-1.6	-2.3	-0.3	1.3	0.3	0.2	0.7
Medication: Cholesterol lowering	0.4	0.7	1.8	1.2	-0.3	-0.3	-0.7	1.0	-0.9	0.5	1.0	1.4	1.2	-0.0	0.6	0.5	0.6
Depression (self-reported)	0.8	1.0	2.5	-1.3	-1.3	-1.3	0.2	-1.4	-0.1	0.8	0.3	-0.6	0.1	-1.4	-0.8	-1.1	-1.6
Medication: Lansoprazole	0.4	0.4	2.1	-0.2	0.6	0.5	-0.9	0.6	-1.4	0.4	-0.5	-0.2	0.6	0.6	1.0	-0.4	0.4
Prospective memory result	0.8	1.0	3.8	-1.3	-1.0	-1.0	-0.1	-0.6	-0.2	-0.2	-0.2	-0.9	-0.8	-1.1	-0.9	-1.6	-1.9
Lung cancer (father)	0.5	0.6	2.3	-0.7	0.4	0.4	-0.9	-0.6	-0.4	-1.2	0.7	-0.6	0.1	0.6	1.2	-1.5	-0.1
Illnesses of mother	1.1	1.4	2.4	-1.2	-1.5	-1.5	0.1	-0.5	-0.1	1.5	1.2	-0.3	0.6	-1.6	-1.1	-1.5	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.9	0.7	1.2	1.1	1.2	0.6	1.0	-1.2	-0.8	-0.3	-1.4	1.1	1.7	0.2	1.1
Pulse wave Arterial Stiffness index	0.3	0.3	1.2	0.5	0.2	0.0	-0.3	-1.1	0.7	-0.1	-0.4	0.9	-0.1	0.0	0.8	0.6	0.2
Impedance of arm (left)	0.4	1.9	6.4	0.9	-0.8	-0.6	-0.4	0.9	-2.2	0.3	2.2	2.5	1.5	-0.5	0.6	2.2	0.6
Arm fat mass (right)	0.0	0.1	0.6	0.0	-0.0	-0.3	-0.8	0.3	0.0	0.0	-0.3	-0.1	0.7	-0.2	0.7	-0.1	-0.3
Trunk predicted mass	0.1	0.5	1.7	-0.1	0.7	0.7	0.2	-0.1	-0.3	-1.3	-1.0	-0.9	-0.7	0.7	0.8	-0.7	0.4
Standing height	0.1	0.7	2.6	-0.1	0.0	0.1	-1.0	0.3	-1.4	-1.6	0.8	1.2	0.5	0.2	1.1	0.2	0.3
Length of working week for main job	2.7	3.0	10.8	2.2	1.6	1.9	3.3	1.6	0.0	-0.3	-0.3	-1.1	-1.1	1.8	2.1	2.2	1.9
Exposure to tobacco smoke at home	0.3	0.4	1.0	0.4	0.6	0.7	-0.4	0.3	1.0	-0.6	-0.2	0.4	0.3	0.7	0.9	0.1	0.8
Breastfed as a baby	1.0	1.3	4.4	-1.0	0.3	0.5	-1.8	-2.1	0.2	-0.5	-0.4	-1.9	-1.1	0.2	1.2	-1.4	-0.4
Tense / ‘highly strung’	0.3	0.4	2.0	1.1	0.3	0.3	0.1	1.4	-0.7	0.8	-0.3	0.3	0.0	0.3	0.4	0.8	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.3	0.1	-0.1	-1.1	0.9	1.2	0.2	-0.3	0.1	-0.5	0.2	0.3	0.2	0.3
Hair/balding pattern: Pattern 4	0.5	1.3	2.8	-0.3	-1.4	-1.4	1.5	1.7	1.0	1.3	1.0	0.7	0.5	-1.4	-0.7	-0.9	-1.2
Birth weight of first child	0.4	0.8	2.8	-0.1	-0.9	-0.8	1.7	0.5	-0.2	1.2	1.1	0.8	0.6	-0.9	-1.0	1.0	-0.7
Peak expiratory flow (PEF)	0.2	0.4	1.8	-0.1	-0.2	-0.3	-1.3	1.1	0.8	0.4	0.4	0.7	-0.1	-0.3	0.9	-0.3	0.1
Pulse wave reflection index	0.6	0.7	2.7	0.6	0.5	0.5	-0.4	-1.6	-1.4	-1.0	-0.6	0.2	-0.2	0.4	1.4	1.0	0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.2	0.5	-0.2	-0.4	-0.7	1.1	0.3	0.3	-0.2	0.4	-0.3	-0.2	-0.2	0.4	-0.4
Loud music exposure frequency	0.7	0.8	3.0	0.8	0.7	0.5	1.5	1.7	0.3	-0.3	-1.3	-1.0	-1.1	0.5	0.2	0.2	0.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.3	-1.5	1.1	0.8	1.4	-1.4	0.7	-0.0	-1.0	-0.1	0.6	0.7	-0.1	-1.0	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.0	-0.0	0.5	0.5	1.4	-0.2	0.9	-0.7	-0.3	0.7	1.3	0.5	1.0	0.7	0.5
Blood clot in the leg (DVT)	1.4	1.8	5.7	-1.0	-1.2	-1.3	-1.6	0.3	-1.8	-0.8	0.0	0.3	-2.0	-1.5	-2.4	0.2	-1.6
Medication: Paracetamol	1.7	2.8	12.0	-1.2	1.1	0.8	-1.3	-3.5	0.4	-2.4	-2.3	-2.1	-1.2	0.6	1.9	-1.2	-0.1
Headache pain in last month	0.3	0.6	1.8	0.3	1.1	1.1	0.3	-0.0	-0.4	-1.2	-1.3	-0.8	-0.7	0.7	0.7	0.6	-0.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	5.1	-1.5	-0.8	-0.9	1.1	-0.8	0.8	0.1	-0.5	-0.6	-0.7	-1.0	-2.3	-0.2	-1.5
Glaucoma (self-reported)	0.4	0.4	1.0	-0.8	-0.8	-0.6	1.0	0.7	-0.4	0.0	0.5	-0.3	0.7	-0.7	-0.2	-0.6	-1.0
Gout (self-reported)	0.2	0.2	1.2	0.5	-0.1	0.1	0.6	0.3	0.2	-0.7	0.4	0.1	-0.8	0.1	0.1	1.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.4	-1.3	-0.7	-0.7	0.5	-1.5	0.3	1.2	0.6	1.2	0.6	-0.9	-1.0	-0.2	-0.9
Medication: Amlodipine	1.5	2.1	5.2	-1.6	-1.1	-1.1	-2.3	1.1	-1.9	0.6	1.3	2.0	1.0	-1.3	-0.6	-1.8	-1.6
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.2	-1.4	-0.7	-0.8	-0.5	-0.5	-0.3	0.4	-0.1	-0.7	0.6	-0.9	-0.0	-1.1	-1.5
Birth weight	1.6	3.5	7.6	2.1	2.2	2.3	2.2	0.1	1.0	-1.6	-1.9	-1.5	-2.8	2.1	1.6	1.5	1.9
Chronic bronchitis/emphysema (mother)	1.7	1.9	3.9	1.2	1.6	1.7	-0.5	-0.8	0.6	-1.9	-1.7	-2.0	-1.2	1.8	1.1	-0.1	1.6
High blood pressure (siblings)	2.4	3.5	11.7	0.3	1.8	1.3	-2.4	-2.1	1.7	-2.3	-3.4	-1.7	-2.8	1.2	1.4	0.0	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.9	2.9	0.2	1.2	1.1	0.9	-0.1	0.4	-1.3	-0.7	-0.1	-1.0	1.1	1.7	0.4	1.2
Body fat percentage	0.1	0.4	2.5	0.4	0.7	0.4	-1.1	0.7	0.3	-0.2	-0.4	-0.1	0.7	0.5	1.6	0.1	0.3
Leg fat percentage (right)	0.3	1.2	3.8	0.6	1.4	1.3	-1.2	0.0	0.8	-1.0	-1.3	-1.6	-0.3	1.3	1.9	-0.1	0.7
Arm fat-free mass (right)	0.1	0.5	2.5	-0.9	0.4	0.2	-0.4	0.0	0.2	-0.8	-0.9	-1.0	-0.3	0.2	0.5	-1.6	-0.4
Exposure to tobacco smoke outside home	1.1	1.5	3.2	-0.6	-1.8	-1.6	1.1	0.4	-0.0	1.4	1.8	0.8	1.2	-1.6	-1.7	0.3	-1.1
Comparative body size at age 10	0.2	0.7	2.1	-0.1	1.2	1.2	0.7	0.2	0.1	0.0	-0.6	-1.0	-0.1	1.0	1.4	-0.5	1.0
Number of full brothers	0.4	0.5	2.8	0.1	-0.3	-0.4	0.7	-0.8	0.0	0.3	0.1	0.8	0.4	-0.4	-1.7	1.5	-0.3
Worry too long after embarrassment	0.8	1.4	4.5	-0.6	-1.0	-1.0	0.7	0.1	0.5	2.1	1.9	1.3	2.1	-0.8	0.7	-0.3	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.2	0.1	-0.8	-0.9	-0.6	0.6	-0.9	0.5	0.2	0.1	0.3	-0.7	-1.0	0.2	-1.1
Wheeze or whistling in the chest in last year	0.8	1.5	3.9	0.9	1.3	1.1	-0.5	-1.3	-0.6	-1.7	-2.0	-0.9	-1.7	1.0	0.4	1.4	0.5
Number of children fathered	0.3	0.3	1.2	0.9	0.3	0.3	-0.3	-0.8	1.1	0.1	-0.3	-0.3	0.6	0.5	0.2	0.6	0.6
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.0	8.2	1.7	2.0	2.3	-0.3	-1.3	0.4	-2.5	-0.7	-0.8	-1.6	2.4	1.8	0.8	2.9
Age at first live birth	0.2	0.3	1.3	0.8	0.3	0.4	0.3	0.5	-0.6	-1.1	-0.4	-0.4	-1.0	0.4	0.3	-0.1	0.0
Pulse wave peak to peak time	0.2	0.3	1.3	-0.5	-0.2	0.1	0.2	1.1	-0.7	-0.2	0.3	-1.0	-0.0	0.1	-0.7	-0.6	-0.0
Health satisfaction	0.4	0.5	2.2	1.2	-0.3	-0.3	0.4	0.6	0.4	0.7	0.7	0.9	0.6	-0.3	0.1	1.5	0.8
Shortness of breath walking on level ground	0.5	0.6	2.0	-0.1	-1.0	-1.0	0.0	-0.7	-0.1	0.1	0.2	-1.0	-0.7	-1.0	-0.3	-1.4	-1.3
Qualifications: College or University degree	0.2	0.5	1.4	-0.3	-0.7	-0.6	0.2	0.2	0.0	1.2	1.2	1.1	1.0	-0.4	0.6	-0.4	0.3
Eye problems/disorders: None of the above	0.4	0.5	2.6	-0.5	-0.5	-0.6	-1.6	-1.0	-0.3	-0.1	-0.1	0.3	-0.6	-0.6	-0.9	0.1	-0.2
Mouth/teeth dental problems: Loose teeth	0.6	0.7	4.9	-0.2	-0.4	-0.2	0.5	-1.4	2.2	-0.0	-0.3	-1.2	-0.1	-0.2	-0.9	-0.0	-0.2
Emphysema/chronic bronchitis	0.9	1.0	2.3	-0.1	0.9	1.1	-0.5	-1.1	-1.4	-1.4	-0.5	0.6	0.5	1.1	0.5	1.2	1.5
Medication for pain relief, constipation, heartburn	0.5	0.8	4.7	0.6	-0.3	-0.2	1.3	2.2	0.5	0.3	0.2	0.7	-1.5	-0.3	-1.1	0.5	0.1
Neck or shoulder pain in last month	0.8	1.1	2.7	0.7	1.2	1.3	0.9	0.7	1.2	-1.1	-1.1	-0.9	-1.3	1.2	0.6	0.1	1.6
Medication: Blood pressure	1.1	2.0	10.7	1.8	1.6	1.6	-0.7	0.5	-0.2	-0.2	-0.5	-0.3	0.1	1.7	3.3	-0.3	2.3
Angina (self-reported)	0.9	1.2	4.4	0.8	1.0	0.9	0.1	-0.5	0.5	-0.8	-2.1	-1.8	-2.0	0.8	0.5	0.1	0.4
Migraine (self-reported)	0.8	1.0	4.1	-0.6	0.8	0.7	0.2	-2.0	1.4	-0.9	-1.2	-1.4	-0.6	0.6	1.0	-1.0	0.1
Medication: Ibuprofen	1.6	1.9	8.7	-0.3	1.5	1.5	1.1	-1.2	1.2	-0.8	-1.9	-2.9	-0.8	1.5	0.3	-0.4	0.9
Medication: Allopurinol	0.4	0.5	1.5	1.1	0.4	0.4	0.9	1.2	-0.4	-0.7	-0.3	-0.2	-0.1	0.4	0.5	1.1	0.8
Medication: Omeprazole	0.3	0.4	3.6	0.3	0.1	0.3	-1.9	-0.5	0.4	0.2	0.3	-0.6	0.3	0.4	0.7	-0.5	-0.0
Medication: Seretide 50 evohaler	0.5	0.6	1.6	0.6	0.8	1.0	0.0	0.9	0.2	-1.3	-0.4	0.1	0.2	1.0	0.9	1.0	1.0
Mean time to correctly identify matches	0.9	1.7	8.5	-0.1	-0.3	-0.2	-0.2	1.0	0.4	1.3	1.8	2.9	2.3	-0.0	0.5	1.7	0.6
Heart disease (mother)	4.3	5.3	11.4	-0.9	-3.0	-3.4	0.8	0.3	0.0	2.9	2.2	3.1	2.9	-3.2	-1.1	0.0	-3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	3.9	1.7	0.5	0.6	-0.3	2.0	0.1	-0.8	0.4	1.0	-0.1	0.8	0.1	1.1	0.9
Whole body fat mass	0.1	0.3	1.7	-0.0	0.3	0.1	-1.1	0.5	0.0	-0.2	-0.3	0.1	0.9	0.2	1.3	-0.2	-0.1
Leg fat mass (right)	0.2	0.6	2.2	0.1	0.8	0.6	-0.9	0.0	0.5	-0.7	-1.1	-1.1	0.2	0.7	1.5	-0.5	0.2
Arm predicted mass (right)	0.1	0.4	1.6	-0.6	0.5	0.4	-0.0	0.2	0.3	-0.9	-1.0	-1.1	-0.4	0.4	0.6	-1.3	-0.1
Pulse rate, automated reading	0.3	1.1	8.8	-0.9	-0.2	-0.2	0.8	-0.3	3.0	0.1	0.5	-0.4	0.1	-0.1	-0.2	-1.8	-1.1
Alcohol intake frequency.	0.1	0.2	0.8	0.4	-0.2	-0.2	0.6	0.9	-0.0	-0.3	0.1	-0.0	-0.4	-0.1	-0.8	0.4	-0.1
Comparative height size at age 10	0.2	0.9	5.2	-0.9	-0.4	-0.2	-1.3	0.7	-2.3	-1.0	1.0	1.0	0.7	-0.3	0.3	-0.5	-0.2
Number of full sisters	0.9	1.1	5.3	0.1	0.0	0.0	-0.1	-0.8	1.1	-1.5	-1.8	-1.4	-2.3	-0.2	-0.2	0.5	-1.0
Suffer from ‘nerves’	0.4	0.7	2.5	-0.1	-0.7	-0.8	-0.0	1.6	1.2	-0.1	-0.5	-0.1	-0.9	-0.9	-0.9	-0.9	-0.9
Overall health rating	0.7	1.5	4.9	1.0	1.7	1.5	-0.2	-0.2	-0.4	-1.4	-1.5	-0.6	-0.0	1.5	2.2	1.1	1.4
Chest pain or discomfort	0.3	0.4	2.1	0.3	0.4	0.2	-0.6	-0.5	0.6	-1.0	-1.4	-0.3	-0.5	0.2	0.3	0.4	-0.7
Had major operations	0.6	0.7	1.8	0.8	1.1	1.0	-0.5	-0.9	0.4	-0.7	-1.3	-0.4	-0.4	1.0	0.7	0.6	0.8
Age at last live birth	0.2	0.3	0.7	0.9	0.5	0.6	0.6	0.3	-0.1	-0.7	-0.3	-0.4	-0.5	0.7	-0.0	0.0	0.5
Family relationship satisfaction	0.5	0.6	4.2	-0.6	-0.5	-0.5	-2.0	0.4	-1.4	-0.3	0.1	-0.2	0.0	-0.7	-0.6	-0.2	-0.5
Leg pain on walking	0.8	1.0	4.8	1.1	0.4	0.4	2.2	0.4	1.8	0.3	-0.1	0.8	0.2	0.3	0.6	1.4	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	3.0	-0.0	-0.6	-0.6	1.7	-0.8	0.2	0.7	-0.3	-0.7	-0.8	-0.5	-1.7	0.3	-1.1
Commuting to job workplace: Car/motor vehicle	1.8	2.0	4.6	0.8	1.9	1.7	0.4	1.0	2.0	-1.6	-1.8	-0.6	-1.0	1.7	2.1	0.9	1.0
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	5.2	-1.7	-1.1	-1.0	-2.3	0.1	-1.7	0.1	1.1	0.9	-0.0	-1.0	-1.4	-1.1	-1.1
Medication: Aspirin	0.9	1.2	4.0	-0.8	-0.9	-1.0	-0.6	-0.9	-1.4	0.9	1.1	0.5	2.0	-0.7	-0.6	-2.0	-0.5
Supplements: Vitamin C	0.7	0.8	4.4	-0.8	0.8	0.9	-0.1	-0.6	-0.4	-0.6	-0.7	-2.1	-0.8	0.7	0.5	-1.4	0.5
Knee pain experienced in last month	2.3	3.6	7.1	2.7	2.2	2.1	0.7	2.6	1.5	-1.6	-1.6	-0.0	-0.9	2.2	1.8	2.5	1.9
Hypertension (Self-reported)	0.4	1.1	5.0	-0.8	-0.4	-0.3	-2.2	1.4	-1.0	0.2	0.9	0.9	0.0	-0.3	0.5	-2.1	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	0.4	0.0	0.3	-0.4	-0.7	-0.1	0.4	0.4	0.0	-0.2	0.3	-0.5	-0.0	0.2
Illnesses of father: Heart disease	0.3	0.5	2.1	0.3	0.4	0.1	-0.3	1.2	0.7	0.1	-1.4	-1.1	-0.6	0.2	-0.3	-0.1	-0.5
Illnesses of siblings: Diabetes	0.6	0.7	1.7	0.3	-1.1	-1.1	-0.2	-0.4	-0.8	1.2	1.3	0.5	1.0	-0.9	-1.1	0.2	-0.5
Smoking status: Previous	0.7	1.1	2.5	1.1	1.3	1.3	0.1	-0.4	0.8	-1.0	-1.3	-0.4	-1.1	1.2	-0.1	1.6	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	4.4	1.3	1.0	0.9	1.5	0.4	0.7	-0.8	-0.0	0.5	0.4	1.2	1.4	1.8	2.1
Whole body fat-free mass	0.0	0.3	1.0	-0.2	0.4	0.3	0.0	0.2	-0.2	-1.0	-0.8	-0.6	-0.4	0.3	0.7	-0.8	0.0
Leg fat-free mass (right)	0.0	0.1	0.7	-0.1	-0.1	-0.2	0.2	0.9	-0.2	-0.4	-0.3	0.3	0.1	-0.2	0.3	-0.4	-0.3
Arm fat percentage (left)	0.0	0.1	0.5	0.4	0.1	-0.1	-0.6	0.6	-0.0	0.1	-0.1	-0.1	0.6	-0.1	0.7	0.3	-0.0
Average weekly red wine intake	1.3	2.0	5.9	-1.5	-1.9	-1.6	0.1	-0.6	-0.8	0.9	2.4	1.4	2.0	-1.6	-0.8	-1.0	-1.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	0.6	0.0	-0.1	-0.9	1.4	0.1	-1.2	-0.4	-0.2	-1.4	-0.1	-0.1	0.3	-0.0
Mood swings	0.4	0.7	2.1	1.3	0.6	0.5	0.5	0.0	1.1	-0.6	-0.6	-0.4	-1.1	0.5	0.8	1.5	0.5
Loneliness, isolation	2.0	2.8	6.1	2.4	1.6	1.7	1.3	-0.1	2.3	-1.6	-0.7	0.1	-0.7	1.8	2.5	1.9	2.0
Long-standing illness, disability or infirmity	0.4	0.6	2.7	1.0	0.7	0.8	0.0	1.0	0.8	-0.8	-0.3	0.2	-0.2	0.9	1.7	0.6	0.5
Ever had bowel cancer screening	0.6	0.8	3.4	0.6	1.1	1.0	0.7	0.6	0.9	-0.3	-0.9	0.2	-0.6	0.9	1.8	0.2	1.0
Diabetes diagnosed by doctor	0.5	0.8	4.8	-0.3	0.7	0.8	-0.9	-0.1	-1.1	-1.0	0.1	0.3	0.4	0.7	2.2	-0.8	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	3.3	-0.6	-1.0	-1.0	0.3	-0.1	0.1	0.8	0.4	0.3	0.2	-0.9	-1.8	-0.9	-0.9
Friendships satisfaction	0.6	0.8	3.9	-1.0	-0.2	-0.1	-2.0	-2.0	0.1	-1.0	0.3	-0.3	-0.1	-0.3	0.2	-0.3	-0.6
Qualifications: nursing, teaching	0.4	0.7	3.2	-1.0	-0.3	-0.4	0.9	-1.8	0.6	0.9	0.4	0.2	1.1	-0.2	1.1	-0.3	-0.1
Commuting to job workplace: Walk	2.9	3.2	5.5	-2.3	-2.1	-2.1	-1.5	-1.9	-0.5	1.3	1.8	0.5	0.9	-2.1	-1.6	-2.4	-2.3
Eye problems/disorders: Cataract	0.5	0.6	2.9	0.4	0.1	0.1	1.7	0.8	0.7	1.1	0.5	0.2	1.0	0.3	0.7	0.4	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.9	0.8	-0.4	-0.4	1.7	-0.4	0.5	0.8	0.1	0.4	0.7	-0.3	-0.0	0.7	0.1
Medication for cholesterol	3.3	5.0	14.3	3.5	2.1	2.3	2.0	0.1	1.3	-1.3	-1.3	-0.4	-2.1	2.3	1.5	3.8	3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.8	-0.7	0.2	-0.2	-0.3	-0.2	-0.9	0.3	-0.9	-0.8	-0.1	-0.4	0.1	-0.4	-0.5
Back pain experienced in last month	0.2	0.3	1.3	-0.4	-0.1	-0.0	-1.0	-0.1	-1.2	-0.3	-0.1	-0.0	-0.3	-0.3	0.6	0.8	-0.3
Mineral and other dietary supplements	0.5	0.7	2.5	1.6	0.7	0.8	0.5	-0.2	1.1	-0.1	0.3	-0.0	-0.1	1.0	1.1	1.3	1.2
Breast cancer (self-reported)	2.3	2.7	7.1	2.3	1.8	1.8	1.5	1.4	0.1	-1.3	-1.3	0.8	-0.6	1.9	1.5	2.7	2.1
Asthma (self-reported)	0.1	0.2	0.6	0.1	-0.0	-0.1	-0.0	-0.7	0.5	-0.3	-0.7	-0.6	-0.6	-0.3	0.5	0.8	-0.8
Osteoporosis (self-reported)	0.6	0.8	1.8	-1.3	-1.0	-0.9	-0.4	-1.3	0.9	-0.3	0.5	-0.1	0.7	-0.9	-0.5	-1.3	-0.9
Osteoarthritis (self-reported)	0.6	0.8	2.5	0.1	1.1	1.1	0.1	0.1	0.8	-0.8	-0.8	-1.6	-1.6	1.0	0.0	-0.3	0.6
Medication: Aspirin	1.4	1.8	5.7	-1.1	-1.1	-1.1	-1.0	-0.9	-1.7	1.1	1.4	0.6	2.4	-0.8	-0.9	-2.4	-0.6
Medication: Gliclazide	0.6	0.7	2.8	-1.3	0.4	0.6	-0.4	-1.0	-1.7	-0.6	-0.3	-0.2	-0.0	0.3	1.2	-1.1	0.2
Illnesses of father: None of the above (group 1)	0.5	0.7	2.0	-0.1	-1.1	-0.6	0.6	0.1	-0.6	1.2	1.4	0.7	1.3	-0.6	-1.0	0.1	0.2
Smoking status: Current	1.4	2.2	4.7	-1.5	-1.8	-2.0	-2.2	-0.6	-1.2	1.1	1.1	1.5	1.3	-1.9	-1.2	-0.8	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.6	-1.0	0.3	0.2	1.0	-1.1	1.5	-0.2	0.1	-0.6	-1.3	0.1	0.6	-1.6	-0.6
Whole body water mass	0.0	0.2	0.9	-0.3	0.4	0.3	-0.0	0.2	-0.2	-1.0	-0.8	-0.5	-0.3	0.3	0.6	-0.8	0.0
Leg predicted mass (right)	0.0	0.1	0.8	-0.1	-0.2	-0.3	0.2	0.9	-0.2	-0.3	-0.2	0.3	0.2	-0.3	0.2	-0.4	-0.4
Arm fat mass (left)	0.0	0.2	0.8	-0.2	-0.1	-0.4	-0.9	0.3	-0.4	0.2	-0.1	-0.2	0.8	-0.3	0.6	-0.4	-0.5
Number of self-reported non-cancer illnesses	0.8	1.3	7.2	2.0	0.8	0.7	-0.5	1.0	0.7	-0.3	0.2	1.0	0.5	0.8	2.7	0.8	1.3
Average weekly champagne plus white wine intake	0.3	0.5	1.8	-1.2	-0.2	-0.1	-0.0	-1.3	-1.2	-0.1	-0.3	-0.6	-0.9	-0.3	-0.3	-0.4	-0.7
Miserableness	0.8	1.4	4.2	1.6	0.9	1.0	0.6	-0.3	1.2	-0.9	-0.2	-0.0	-0.8	1.2	2.1	1.8	1.7
Guilty feelings	0.6	0.9	4.2	1.5	-0.1	0.1	1.1	-0.2	1.4	0.1	0.7	0.8	0.3	0.2	1.3	2.1	0.6
Wears glasses or contact lenses	0.5	0.6	2.1	0.0	-0.5	-0.6	-1.3	0.4	1.4	0.8	0.4	1.5	0.7	-0.5	0.4	0.5	-0.6
Ever taken oral contraceptive pill	1.3	1.4	5.2	1.1	0.2	0.3	2.3	-0.6	1.8	1.3	0.9	1.1	1.1	0.5	0.4	1.6	1.3
Hearing aid user	0.4	0.5	2.3	-0.6	-0.0	-0.3	-0.6	-0.8	1.5	-0.8	0.0	0.5	0.6	-0.2	1.2	-0.3	-0.6
Mother’s age at death	0.4	0.5	1.4	-0.4	1.0	0.9	0.6	-0.2	0.5	-0.6	-1.2	-0.8	-1.0	0.8	0.1	-0.2	0.3
Financial situation satisfaction	0.5	0.6	1.1	-0.1	-0.6	-0.7	-1.0	0.5	-0.7	0.7	0.7	1.0	0.9	-0.7	-0.8	0.9	-1.0
Tinnitus: Yes, now most or all of the time	2.8	3.3	7.3	-2.5	-1.8	-1.9	-2.7	-1.9	-0.6	0.8	0.5	0.2	0.8	-2.0	-1.9	-2.4	-2.6
Commuting to job workplace: Public transport	0.7	0.8	3.5	-1.8	0.2	0.2	-0.8	-1.6	-0.1	-0.0	-0.0	-0.6	0.8	0.1	0.6	-1.9	-0.5
Eye problems/disorders: Glaucoma	0.1	0.2	0.7	-0.2	0.1	0.2	0.8	0.5	-0.3	-0.7	-0.0	0.0	0.8	0.1	0.3	-0.2	-0.0
Medication: Blood pressure	2.4	4.6	9.5	-3.1	-1.9	-1.8	-2.6	1.1	-2.7	1.1	1.7	1.8	2.2	-1.8	-1.4	-2.9	-2.7
Pain type(s) experienced in last month: Hip pain	0.3	0.3	2.3	0.3	0.1	0.1	0.5	0.1	0.4	0.1	-0.8	-0.0	-0.3	-0.1	-0.1	1.1	-1.5
Supplements: Fish oil (including cod liver oil)	0.3	0.5	2.1	-0.7	0.3	0.2	0.7	-0.2	-0.4	-0.6	-1.5	-0.9	-1.0	0.0	-0.2	-0.7	-0.4
High cholesterol (Self-reported)	1.6	2.8	4.9	-2.1	-2.0	-1.8	-2.1	-0.6	-1.5	0.7	2.1	0.9	0.9	-1.9	-1.2	-2.0	-2.2
Medication: Bendroflumethiazide	0.7	1.0	4.6	-0.5	1.0	0.9	-1.1	0.1	0.4	-1.5	-0.9	-0.7	-0.7	0.9	1.0	-2.1	0.7
Medication: Paracetamol	2.1	3.3	8.6	-0.9	1.7	1.4	-0.1	-2.9	1.0	-2.3	-2.9	-2.5	-1.6	1.2	2.1	-1.1	0.9
Medication: Lisinopril	0.3	0.4	1.5	-0.5	-0.0	-0.1	-1.2	-0.6	-0.5	-0.2	-0.5	-0.0	-0.4	-0.2	0.9	-1.1	-0.8
Medication: Atorvastatin	0.4	0.5	3.2	-0.4	-0.3	-0.2	-1.0	0.0	-1.8	0.2	0.5	0.0	1.1	-0.2	0.8	-0.3	-0.0
Illnesses of father: High blood pressure	0.7	0.8	2.2	0.2	1.2	0.9	-0.2	-1.0	0.9	-1.1	-1.4	-1.1	-1.5	0.8	0.5	-0.1	0.2
Alcohol drinker status: Never	1.3	1.6	6.2	-1.7	0.6	0.5	0.7	-1.7	-0.0	-0.6	-1.2	-2.5	-0.6	0.2	0.5	-2.5	-0.4
Ever smoked	0.2	0.4	2.6	0.3	0.1	0.1	-0.6	-0.7	1.0	0.1	-0.3	1.1	-0.1	-0.0	-0.3	1.6	0.3
Basal metabolic rate	0.0	0.2	0.8	-0.0	0.5	0.3	0.0	0.4	-0.1	-0.9	-0.7	-0.4	-0.2	0.3	0.9	-0.5	0.1
Leg fat percentage (left)	0.3	1.1	3.3	0.7	1.4	1.2	-1.1	0.3	1.0	-0.6	-1.3	-1.6	-0.2	1.2	1.8	-0.1	0.7
Arm fat-free mass (left)	0.1	0.6	2.0	-0.7	0.7	0.5	-0.3	-0.3	0.2	-1.0	-1.2	-1.1	-0.4	0.5	0.8	-1.4	-0.1
Number of operations (self-reported)	0.5	0.7	2.8	0.8	-0.2	-0.3	1.7	1.0	0.0	1.5	0.2	1.3	0.5	-0.3	0.3	1.0	0.0
Average weekly beer plus cider intake	0.3	0.4	1.7	1.3	-0.1	-0.0	-0.7	1.0	-0.2	0.2	0.3	-0.8	-1.1	-0.1	0.3	-0.2	1.0
Irritability	0.6	1.0	4.1	1.4	0.4	0.4	2.0	0.7	1.4	0.5	-0.3	-0.2	-0.8	0.2	0.8	1.9	0.2
Risk taking	1.5	2.2	5.3	0.9	-0.8	-0.8	1.9	2.2	1.5	1.7	1.4	2.3	1.3	-0.7	-0.2	2.3	0.1
Ever had prostate specific antigen (PSA) test	1.6	1.8	8.3	2.1	-0.3	-0.1	0.9	1.6	2.1	0.7	1.2	1.5	-0.3	0.0	-0.1	2.9	0.5
Fractured/broken bones in last 5 years	0.5	0.7	2.5	0.3	0.2	0.2	-0.3	-0.4	1.4	0.9	0.2	0.6	1.4	0.4	1.6	1.0	0.8
Age started oral contraceptive pill	1.9	2.4	10.2	-1.9	-1.1	-1.1	-1.9	0.1	-1.9	0.3	0.2	-0.9	-0.1	-1.2	-3.2	-2.4	-1.5
Diastolic blood pressure, automated reading	1.3	4.0	14.1	-1.3	2.0	1.7	-3.8	-1.2	0.2	-2.4	-2.4	-2.0	-1.2	1.5	2.2	-2.8	0.1
Ever depressed for a whole week	0.3	0.4	1.6	-0.2	0.1	-0.1	-0.2	0.7	0.3	0.2	-1.2	-1.1	-1.2	-0.3	-0.7	-0.2	-0.6
Unable to work because of sickness or disability	0.6	0.7	3.3	-0.9	-0.3	-0.6	-1.0	-0.2	1.0	0.2	-1.3	-0.6	-0.2	-0.8	-0.1	-1.1	-1.8
Commuting to job workplace: Cycle	0.6	0.7	2.0	-0.0	1.1	1.2	0.5	-1.0	0.5	-0.2	-1.1	-0.2	0.1	1.2	1.4	0.4	1.1
Myopia	2.3	3.3	13.0	-1.3	-1.7	-1.4	-0.0	0.5	-0.2	2.0	3.1	3.2	3.6	-1.2	0.6	0.4	-1.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	5.0	0.9	0.5	0.4	2.2	-0.9	0.8	-0.4	-1.0	-1.0	-0.5	0.5	-1.0	2.0	0.4
Cholesterol lowering medication	2.1	3.1	10.0	-3.1	-0.9	-1.1	-2.4	-1.4	-0.8	0.7	0.4	-0.5	1.2	-1.3	0.1	-3.2	-2.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.0	-0.4	-0.5	-0.3	-1.4	-0.7	-0.0	0.9	1.0	-0.0	0.4	-0.3	-0.2	-0.7	-0.4
Pain experienced in last month	0.6	1.1	3.0	-1.2	-1.0	-1.0	0.2	-0.3	-0.3	1.5	1.2	0.8	1.4	-0.8	-0.7	-1.7	-0.6
Supplements: Calcium	0.5	0.5	2.3	-0.8	-0.5	-0.1	-0.9	-1.5	-0.5	-0.4	0.8	-1.0	0.3	-0.3	0.6	-0.7	-0.5
Basal cell carcinoma (self-reported)	0.5	0.6	1.5	-1.2	0.0	-0.2	-0.7	-0.6	-0.9	0.5	-0.7	-0.2	0.6	-0.1	-1.2	-1.1	-1.0
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	0.2	-0.7	-0.7	-0.8	-0.2	-0.9	0.1	0.1	-0.3	-0.5	-0.6	-0.6	-0.8	-0.5
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.6	-0.8	-0.8	-0.8	-1.2	0.4	-1.4	-0.9	-0.3	0.1	-2.1	-1.1	-2.1	0.3	-1.4
Heart disease (siblings)	0.6	0.7	3.9	0.0	-0.3	-0.4	-1.3	-2.0	-0.5	0.0	-0.8	-1.0	-0.7	-0.4	-0.1	-0.9	-1.0
Alcohol drinker status: Previous	0.9	1.0	3.5	1.3	1.0	1.0	-1.2	0.4	0.1	-1.9	-0.6	-0.6	-1.8	1.0	0.5	0.7	0.6
Pack years of smoking	0.3	0.4	1.3	0.2	0.7	0.7	-1.1	-0.1	-0.4	-1.1	-0.5	-0.8	0.2	0.9	-0.1	-0.6	0.1
Impedance of whole body	0.1	0.7	2.4	0.5	-0.1	-0.0	-0.4	0.1	-0.7	0.2	1.3	1.5	1.1	0.0	0.9	1.5	0.6
Leg fat mass (left)	0.1	0.5	1.9	-0.0	0.7	0.4	-0.8	0.3	0.4	-0.4	-1.0	-1.0	0.4	0.5	1.4	-0.5	0.1
Arm predicted mass (left)	0.1	0.6	2.0	-0.8	0.7	0.5	-0.5	-0.4	0.3	-1.0	-1.3	-1.2	-0.4	0.5	0.8	-1.4	-0.3