TWAS hub - ARHGAP29

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.184	0.0470	7.0e-08	0.059	0.058	0.067	0.061	0.072	9.4e-08	1.4e-07	1.5e-08	6.9e-08	4.6e-09
2	TCGA	Brain Lower Grade Glioma	0.045	0.0218	3.8e-03	0.004	0.014	0.009	NA	0.011	1.1e-01	8.1e-03	2.7e-02	NA	1.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Cardiovascular Disease	5.1	17.0	31.8	-1.5	-5.6
Heart disease (mother)	4.7	5.7	6.5	-2.2	-2.5
Ever highly irritable/argumentative for 2 days	4.4	5.3	10.5	-3.2	0.4
Illnesses of father: High blood pressure	4.0	5.0	6.9	2.6	1.8
Illnesses of siblings	3.5	4.9	9.7	-0.2	3.1
Ever depressed for a whole week	3.5	4.3	4.8	-2.2	-1.9
High blood pressure	3.1	8.5	15.4	1.3	-3.9
Number of full sisters	3.1	3.8	7.2	-2.7	-0.6
Relative age voice broke	3.0	4.5	9.0	-0.1	3.0
Stomach or abdominal pain in last month	3.0	3.7	4.6	-2.1	1.7
Number of self-reported non-cancer illnesses	3.0	5.1	9.3	-1.0	-3.0
Type 2 Diabetes (T2D) (2012)	2.9	3.3	6.7	2.6	-0.1
Vascular/heart problems diagnosed by doctor	2.9	8.0	15.4	-0.8	3.9
Hypertension (Self-reported)	2.8	7.7	13.8	1.3	-3.7
Irritable Bowel Disease (IBD)	2.7	6.5	11.3	1.3	3.4
Ever unenthusiastic/disinterested for a whole week	2.7	3.3	4.5	-2.1	-1.5
Prospective memory result	2.6	3.2	6.2	0.5	2.5
Diastolic blood pressure, automated reading	2.6	8.0	8.3	2.8	-2.9
Blood Platelet Count	2.3	26.8	27.9	5.1	-5.3
High blood pressure (siblings)	2.3	3.2	5.4	1.1	-2.3
Tinnitus: Yes, now most or all of the time	2.3	2.7	5.3	2.3	0.1
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	5.2	-2.3	-0.8
Schizophrenia vs Biploar Disorder	2.2	2.9	4.8	2.2	1.0
Alzheimer’s Disease (in mother)	2.2	2.6	2.6	1.6	1.6
Relative age of first facial hair	2.2	4.5	8.8	0.4	3.0
Hair/balding pattern: Pattern 3	2.2	3.3	3.5	1.9	1.8
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	4.4	-2.1	-0.6
Number of live births	2.1	3.0	3.6	-1.9	-1.5
Ulcerative Colitis (UC)	2.0	3.7	6.4	1.0	2.5
Mouth/teeth dental problems: Dentures	2.0	3.4	5.0	-1.3	-2.2
High cholesterol (Self-reported)	2.0	3.5	5.4	-1.2	-2.3
Crohns Disease (2017)	1.9	4.1	7.0	1.1	2.6
Supplements: Zinc	1.9	2.1	3.0	1.7	1.1
Supplements: Glucosamine	1.9	2.5	4.0	1.0	2.0
Blood clot in the leg (DVT)	1.9	2.5	4.2	-2.0	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	3.5	1.9	-0.9
Primary Biliary Cirrhosis	1.8	2.5	4.8	0.6	2.2
Systolic Blood Pressure	1.8	9.1	17.2	1.0	-4.2
Alcohol usually taken with meals	1.8	2.9	3.8	-1.9	1.4
Wheeze or whistling in the chest in last year	1.8	3.1	5.0	2.2	1.1
Medication: Allopurinol	1.8	2.4	4.0	-0.9	-2.0
Mineral and other dietary supplements	1.8	2.4	2.8	-1.7	-1.4
Chronotype (morning person)	1.7	3.9	7.5	-0.5	-2.7
Pulse wave reflection index	1.7	2.1	3.6	1.9	-0.8
Qualifications: College or University degree	1.7	5.5	5.9	2.3	2.4
Medication: Atorvastatin	1.7	2.1	2.5	-1.6	-1.3
Neuroticism (2016)	1.6	2.4	3.1	-1.3	-1.8
Lung FEV1/FVC ratio	1.6	8.1	10.7	-3.3	-2.3
Systolic blood pressure, automated reading	1.6	4.7	4.8	2.1	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	4.2	-2.0	-0.9
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	4.2	1.0	2.1
Medication: Blood pressure	1.6	2.9	5.8	0.1	-2.4
Pack years of smoking	1.6	2.3	4.4	-0.4	-2.1
Blood White Count	1.5	11.2	18.7	-1.9	-4.3
Qualifications: None of the above	1.5	3.2	6.3	0.4	-2.5
Worrier / anxious feelings	1.5	2.8	5.3	0.5	2.3
Medication: Paracetamol	1.5	2.6	3.5	1.3	1.9
Medication: Ventolin 100micrograms inhaler	1.5	1.9	3.1	1.8	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	3.8	-0.3	-1.9
Risk taking	1.5	2.2	3.3	1.8	1.0
Alcohol drinker status: Previous	1.5	1.7	3.2	1.8	0.4
Breast Cancer	1.4	3.4	5.8	-1.0	-2.4
Schizophrenia (2014)	1.4	3.2	3.6	1.7	1.9
High blood pressure (mother)	1.4	2.0	2.8	1.7	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	4.2	0.5	2.1
Ever smoked	1.4	2.4	2.9	-1.4	1.7
Vitamin and mineral supplements	1.3	1.7	2.5	-1.6	-1.0
Pack years adult smoking proportion	1.3	2.0	3.8	-0.5	-1.9
Current tobacco smoking	1.3	2.1	4.0	-2.0	-0.4
Medication: Levothyroxine sodium	1.3	2.2	3.6	-0.9	1.9
Time employed in main current job	1.3	1.5	1.6	1.3	1.2
Happiness	1.3	1.6	2.8	-1.7	0.6
Medication: Amlodipine	1.3	1.8	3.1	-0.7	-1.8
Tinnitus: Yes, but not now, but have in the past	1.2	1.2	2.0	-0.7	1.4
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	1.7	-1.3	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.8	0.2	1.7
Loneliness, isolation	1.2	1.7	2.2	-1.1	-1.5
Alcohol drinker status: Never	1.2	1.4	1.7	-1.0	-1.3
Mean Putamen Volume	1.1	1.3	1.6	1.0	-1.3
Diabetes (mother)	1.1	1.4	2.5	-1.6	-0.4
Medication: Atenolol	1.1	1.4	1.9	1.4	-0.9
Qualifications: A levels/AS levels or equivalent	1.1	2.3	4.5	0.4	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.3	2.1	0.8	1.4
Chronic bronchitis/emphysema (mother)	1.1	1.2	2.5	1.6	-0.1
Breast cancer (self-reported)	1.1	1.3	2.2	1.5	0.6
Major Depression (MDD)	1.0	1.2	2.2	-1.5	-0.4
Fasting Glucose	1.0	1.2	1.3	1.0	1.1
Had other major operations	1.0	1.3	1.7	-1.3	-0.9
Number of full brothers	1.0	1.3	2.0	0.8	-1.4
Age at first live birth	1.0	1.7	2.6	0.9	1.6
Health satisfaction	1.0	1.3	2.7	-1.6	-0.0
Neck or shoulder pain in last month	1.0	1.4	2.8	0.3	1.7
Smoking status: Previous	1.0	1.5	2.1	-1.0	1.4
Ever had bowel cancer screening	1.0	1.2	2.2	1.5	0.4
Eye problems/disorders: Cataract	1.0	1.1	2.2	1.5	-0.2
Financial situation satisfaction	1.0	1.3	2.6	-1.6	-0.0
Bipolar Disorder (2018)	0.9	1.4	2.8	-0.2	1.7
Crohns Disease (2012)	0.9	1.4	2.6	0.5	1.6
Diabetes (father)	0.9	1.1	1.4	1.2	0.9
Forced vital capacity (FVC)	0.9	3.4	6.7	-0.2	2.6
Pulse rate	0.9	1.5	2.7	-1.6	-0.6
Pulse wave Arterial Stiffness index	0.9	1.1	1.4	0.8	-1.2
Number of children fathered	0.9	1.0	1.5	0.7	1.2
Pulse wave peak to peak time	0.9	1.1	1.6	-0.7	1.3
Migraine (self-reported)	0.9	1.2	1.6	-1.3	0.8
Average weekly champagne plus white wine intake	0.9	1.3	2.3	0.6	1.5
Hearing aid user	0.9	1.0	1.9	-1.4	-0.3
Supplements: Calcium	0.9	1.0	1.6	0.5	1.3
Ulcerative Colitis	0.8	1.2	2.1	0.6	1.4
Townsend deprivation index at recruitment	0.8	1.1	1.4	-0.9	-1.2
Past tobacco smoking	0.8	1.5	1.8	1.3	-1.1
Pain all over the body in last month	0.8	0.9	1.7	1.3	-0.2
Medication: Simvastatin	0.8	1.2	1.3	-1.1	-1.0
Alcohol intake versus 10 years previously	0.8	1.2	2.5	-0.1	1.6
Medication: Omeprazole	0.8	0.9	1.0	-0.9	-1.0
Friendships satisfaction	0.8	1.1	1.5	-0.8	1.2
Asthma (self-reported)	0.8	1.6	3.2	1.8	-0.2
Smoking status: Current	0.8	1.3	2.2	-1.5	-0.6
Miserableness	0.8	1.4	2.5	-1.6	-0.6
Basal cell carcinoma (self-reported)	0.8	1.0	1.1	-1.0	1.0
Alzheimer’s Disease (including proxy)	0.7	1.0	1.2	1.1	0.9
Medication: Co-codamol	0.7	0.8	1.6	-0.0	1.3
Impedance of leg (right)	0.7	3.6	5.4	1.4	-2.3
Impedance of leg (left)	0.7	3.5	4.0	1.7	-2.0
Trunk fat-free mass	0.7	3.9	7.8	-0.1	2.8
Falls in the last year	0.7	0.9	1.5	1.2	0.5
Asthma	0.7	1.4	2.8	1.7	-0.2
Trunk predicted mass	0.7	3.8	7.6	-0.1	2.8
Breastfed as a baby	0.7	0.9	0.9	1.0	-0.9
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	1.6	-1.2	1.1
Forced vital capacity (FVC), Best measure	0.7	2.7	4.5	-0.9	2.1
Medication for pain relief, constipation, heartburn	0.7	1.2	2.1	-0.6	-1.4
Mean time to correctly identify matches	0.7	1.2	1.9	-0.8	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.3	-1.1	-0.6
Illnesses of siblings: Diabetes	0.7	0.9	1.8	-0.1	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.3	-1.5	0.7
Leg fat-free mass (right)	0.7	3.6	7.1	-0.2	2.7
Number of operations (self-reported)	0.7	1.0	1.9	0.3	-1.4
Myopia	0.7	1.0	1.3	0.8	1.1
Heart disease (siblings)	0.7	0.9	1.4	1.2	-0.6
Bipolar Disorder or Schizophrenia	0.6	1.5	2.9	0.5	1.7
Bipolar Disorder (2011)	0.6	0.6	0.6	0.7	0.8
Smoking Status	0.6	1.5	2.7	-1.6	0.6
Respiratory disease	0.6	1.4	2.5	1.6	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	2.7	0.5	-1.6
Medication: Cholesterol lowering	0.6	0.9	1.7	-1.3	-0.2
Standing height	0.6	5.6	11.0	0.4	3.3
Birth weight of first child	0.6	1.0	2.0	-0.2	1.4
Arm fat-free mass (right)	0.6	3.0	5.4	0.7	2.3
Shortness of breath walking on level ground	0.6	0.7	1.4	-1.2	-0.2
Medication: Ibuprofen	0.6	0.8	0.8	0.9	0.8
Arm predicted mass (right)	0.6	3.0	5.6	0.7	2.4
Whole body fat-free mass	0.6	3.5	7.0	0.1	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.2	-1.5	-0.4
Whole body water mass	0.6	3.3	6.6	-0.1	2.6
Leg predicted mass (right)	0.6	3.4	6.8	-0.1	2.6
Ever taken oral contraceptive pill	0.6	0.6	1.1	0.4	-1.1
Medication: Blood pressure	0.6	1.0	1.7	0.6	-1.3
Medication: Lisinopril	0.6	0.8	1.0	-1.0	-0.8
Age started oral contraceptive pill	0.6	0.8	1.4	1.2	0.4
Unable to work because of sickness or disability	0.6	0.7	1.5	0.2	-1.2
Coronary Artery Disease (CAD)	0.5	0.6	0.9	-0.5	0.9
HDL Cholesterol	0.5	0.8	1.5	0.3	-1.2
Sensitivity / hurt feelings	0.5	0.9	1.7	1.3	0.2
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.4	-1.2	0.0
Angina	0.5	0.7	1.2	-0.3	-1.1
Medication for hormone replacement therapy	0.5	0.6	0.9	-0.5	1.0
Medication: Metformin	0.5	0.8	1.2	-1.1	-0.5
Leg fat-free mass (left)	0.5	2.7	5.4	-0.2	2.3
Taking other prescription medications	0.5	0.7	1.4	-1.2	0.1
Leg predicted mass (left)	0.5	2.5	4.9	-0.2	2.2
Hearing difficulty/problems with background noise	0.5	0.7	0.8	-0.9	0.8
Financial difficulties in last 2 years	0.5	0.7	1.4	-0.0	1.2
Heart attack	0.5	0.6	0.7	0.8	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.0	1.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	1.7	-1.3	1.1
Exposure to tobacco smoke at home	0.5	0.5	1.1	-0.2	1.0
Hair/balding pattern: Pattern 4	0.5	1.3	2.5	0.3	-1.6
Headache pain in last month	0.5	0.9	1.7	0.0	1.3
Gout (self-reported)	0.5	0.7	0.9	-0.7	-1.0
Leg fat percentage (right)	0.5	1.9	3.0	0.9	-1.7
Worry too long after embarrassment	0.5	0.8	1.6	-1.3	-0.1
Eye problems/disorders: None of the above	0.5	0.5	0.8	-0.6	0.9
Chest pain or discomfort	0.5	0.7	1.3	0.4	1.1
Medication for cholesterol	0.5	0.7	1.5	0.0	1.2
Supplements: Fish oil (including cod liver oil)	0.5	0.6	0.7	0.8	0.8
Basal metabolic rate	0.5	2.6	5.2	0.1	2.3
Arm fat-free mass (left)	0.5	2.6	5.1	0.3	2.3
Pain experienced in last month	0.5	0.8	1.4	-0.4	-1.2
Arm predicted mass (left)	0.5	2.6	5.1	0.3	2.3
LDL Cholesterol	0.4	0.6	0.6	-0.8	-0.8
Blood Eosinophil Count	0.4	3.4	6.5	-0.5	-2.5
Height	0.4	7.5	14.4	0.8	3.8
Average weekly spirits intake	0.4	0.5	0.6	-0.6	-0.8
Hearing difficulty/problems: Yes	0.4	0.6	1.2	0.3	1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.8	-0.6	-0.9
Trunk fat percentage	0.4	1.4	1.8	1.0	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.8	-0.9	0.4
Hair/balding pattern: Pattern 2	0.4	0.5	0.9	-0.2	1.0
Medication: Ramipril	0.4	0.5	0.9	0.1	-0.9
Impedance of arm (right)	0.4	1.7	2.8	-0.8	-1.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	1.9	-0.8	1.4
Lung cancer (father)	0.4	0.4	0.6	0.8	-0.5
Illnesses of mother	0.4	0.5	0.8	-0.9	0.5
Body fat percentage	0.4	1.5	2.4	0.7	-1.6
Emphysema/chronic bronchitis	0.4	0.5	0.7	-0.5	0.8
Angina (self-reported)	0.4	0.5	0.9	-0.1	-1.0
Medication: Seretide 50 evohaler	0.4	0.4	0.5	0.7	-0.6
Alcohol intake frequency.	0.4	1.0	1.8	-1.3	-0.5
Family relationship satisfaction	0.4	0.4	0.7	-0.8	0.4
Long-standing illness, disability or infirmity	0.4	0.6	1.0	-1.0	-0.4
Diabetes diagnosed by doctor	0.4	0.7	1.3	-1.1	-0.3
Osteoarthritis (self-reported)	0.4	0.6	1.0	-0.4	-1.0
Leg fat percentage (left)	0.4	1.6	2.1	1.1	-1.4
Commuting to job workplace: Cycle	0.4	0.5	0.8	0.5	0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.6	0.6	0.8
Impedance of whole body	0.4	2.0	3.3	0.8	-1.8
Schizophrenia (2018)	0.3	0.6	0.7	0.7	0.8
Ovarian Cancer	0.3	0.3	0.5	0.7	0.4
Body Mass Index (BMI) (2010)	0.3	0.4	0.5	-0.7	0.5
Triglycerides	0.3	0.4	0.6	-0.7	0.5
Blood Red Count	0.3	2.8	3.7	1.4	-1.9
Hypothyroidism (self reported)	0.3	0.7	0.8	-0.7	0.9
Lung FVC	0.3	1.3	1.8	-1.3	1.0
Number of treatments/medications taken	0.3	0.5	0.7	-0.6	-0.9
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.6	0.7	-0.3
Average weekly fortified wine intake	0.3	0.4	0.7	0.8	-0.2
Maternal smoking around birth	0.3	0.4	0.4	0.7	0.6
Sitting height	0.3	2.0	2.9	1.1	1.7
Chronic bronchitis/emphysema (father)	0.3	0.4	0.7	-0.8	-0.3
Mouth/teeth dental problems	0.3	0.4	0.8	0.9	0.3
Diabetes (self-reported)	0.3	0.5	0.6	-0.8	-0.5
Fluid intelligence score	0.3	0.6	0.7	-0.9	-0.7
Depression (self-reported)	0.3	0.3	0.5	-0.7	-0.4
Medication: Lansoprazole	0.3	0.3	0.7	0.0	-0.8
Length of working week for main job	0.3	0.3	0.7	-0.0	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.7	-0.9	0.4
Birth weight	0.3	0.6	1.3	1.1	0.1
Exposure to tobacco smoke outside home	0.3	0.4	0.5	0.5	0.7
Comparative body size at age 10	0.3	0.9	1.4	-0.6	-1.2
Comparative height size at age 10	0.3	1.9	3.3	-0.6	1.8
Had major operations	0.3	0.3	0.3	0.6	0.5
Supplements: Vitamin C	0.3	0.4	0.4	0.6	-0.6
Knee pain experienced in last month	0.3	0.5	1.0	0.2	1.0
Mood swings	0.3	0.6	1.1	0.2	1.1
Medication: Gliclazide	0.3	0.3	0.4	-0.7	0.4
Guilty feelings	0.3	0.4	0.5	-0.7	0.6
Medication: Paracetamol	0.3	0.5	0.6	0.6	0.8
Irritability	0.3	0.5	1.0	-1.0	0.0
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.6	-0.5	0.7
Cholesterol lowering medication	0.3	0.4	0.7	-0.4	-0.8
Depression (Nagel 2018)	0.2	0.4	0.5	-0.5	0.7
Worry (Nagel 2018)	0.2	0.4	0.6	0.3	0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.3	-0.4	-0.6
Reaction Time	0.2	0.4	0.6	0.4	-0.8
Lupus	0.2	0.3	0.5	0.4	-0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	-0.3	-0.6
Severe depression (siblings)	0.2	0.2	0.3	0.3	0.5
Fed-up feelings	0.2	0.4	0.7	-0.9	0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.4	-0.2	0.7
Serious illness, injury or assault to yourself	0.2	0.3	0.4	0.6	-0.4
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.8	0.1	-0.9
Number of incorrect matches in round	0.2	0.3	0.4	-0.7	-0.4
Had menopause	0.2	0.2	0.3	0.6	0.4
Noisy workplace	0.2	0.3	0.3	-0.6	0.5
Impedance of arm (left)	0.2	0.8	1.5	-0.4	-1.2
Tense / ‘highly strung’	0.2	0.3	0.3	-0.6	-0.5
Loud music exposure frequency	0.2	0.3	0.3	0.6	-0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	0.1	0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	-0.7	0.3
Pulse rate, automated reading	0.2	0.6	1.1	-1.1	0.1
Overall health rating	0.2	0.4	0.4	-0.7	-0.6
Age at last live birth	0.2	0.3	0.4	0.4	0.6
Leg pain on walking	0.2	0.3	0.5	-0.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.3	-0.5	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	0.4	0.5
Arm fat percentage (left)	0.2	0.7	1.3	-0.2	-1.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.5	0.2	-0.7
Qualifications: nursing, teaching	0.2	0.3	0.3	0.5	-0.5
Back pain experienced in last month	0.2	0.2	0.3	0.5	0.5
Medication: Aspirin	0.2	0.2	0.5	0.7	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.3	0.5	-0.1	0.7
Wears glasses or contact lenses	0.2	0.2	0.3	-0.6	0.1
Commuting to job workplace: Public transport	0.2	0.2	0.5	0.1	0.7
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	0.7	0.3
Average weekly beer plus cider intake	0.2	0.3	0.4	-0.7	-0.3
Fractured/broken bones in last 5 years	0.2	0.2	0.2	-0.5	-0.5
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	-0.7	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	-0.6	-0.3
Age at First Birth	0.1	0.1	0.2	0.4	-0.2
HbA1C	0.1	0.1	0.2	-0.5	0.0
Rheumatoid Arthritis	0.1	0.2	0.4	0.6	0.2
Heel T-Score	0.1	0.7	0.8	0.8	-0.9
BMI	0.1	0.4	0.9	0.9	0.1
Allergy or Eczema	0.1	0.3	0.6	0.8	-0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	-0.1	-0.5
Hair Pigment	0.1	1.9	2.4	1.6	1.1
Hand grip strength (left)	0.1	0.4	0.7	0.0	-0.8
Hand grip strength (right)	0.1	0.1	0.2	-0.3	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.3	0.2	-0.6
Multivitamins +/- minerals	0.1	0.1	0.2	0.1	0.4
Trunk fat mass	0.1	0.4	0.7	0.8	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	-0.6	0.1
Allergy	0.1	0.1	0.1	-0.3	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	0.6	0.0
Weight	0.1	0.7	1.2	0.4	1.1
Arm fat percentage (right)	0.1	0.6	1.1	-0.2	-1.0
Hip circumference	0.1	0.3	0.3	0.6	-0.5
Father’s age at death	0.1	0.2	0.3	-0.5	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.4	-0.6	-0.1
Peak expiratory flow (PEF)	0.1	0.3	0.6	-0.8	-0.2
Glaucoma (self-reported)	0.1	0.1	0.2	0.5	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.2	-0.3
Whole body fat mass	0.1	0.3	0.4	0.6	-0.5
Leg fat mass (right)	0.1	0.2	0.4	0.6	-0.3
Medication: Aspirin	0.1	0.1	0.2	0.4	-0.3
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.4	-0.3
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.5	0.1
Osteoporosis (self-reported)	0.1	0.2	0.3	0.2	-0.5
Mother’s age at death	0.1	0.1	0.1	0.4	0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	-0.1	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	-0.2	-0.3
Leg fat mass (left)	0.1	0.3	0.5	0.7	-0.0
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	0.3	0.2
Neuroticism (Nagel 2018)	0.0	0.0	0.1	-0.2	0.1
Prostate Cancer	0.0	0.0	0.1	-0.1	0.2
Waist Hip Ratio (WHR)	0.0	0.2	0.3	-0.6	0.0
Neuroticism	0.0	0.1	0.1	-0.1	0.3
Tanning	0.0	0.2	0.3	0.2	0.6
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.0	0.1
Age when periods started (menarche)	0.0	0.0	0.0	-0.2	0.0
Qualifications: CSEs or equivalent	0.0	0.0	0.1	0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	-0.3	0.0
Body mass index (BMI)	0.0	0.1	0.2	0.2	-0.4
Waist circumference	0.0	0.0	0.0	0.0	-0.2
Nervous feelings	0.0	0.1	0.1	0.3	-0.1
Neuroticism score	0.0	0.1	0.2	-0.4	0.2
Arm fat mass (right)	0.0	0.0	0.0	0.2	-0.1
Suffer from ‘nerves’	0.0	0.0	0.0	-0.2	-0.1
Average weekly red wine intake	0.0	0.0	0.0	-0.1	0.2
Arm fat mass (left)	0.0	0.0	0.0	-0.0	-0.0
Medication: Bendroflumethiazide	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ARHGAP29

Models

Trait associations