Hub : Genes

ASL

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1800 0.0780 6.3e-15 0.132 0.130 0.133 0.132 0.135 8.0e-16 1.4e-15 6.9e-16 8.8e-16 3.7e-16
2 GTEx Artery Tibial 0.0623 0.0363 1.1e-03 0.029 NA 0.009 NA 0.013 2.5e-03 NA 6.5e-02 NA 3.1e-02
3 GTEx Cells Transformed fibroblasts 0.0770 0.0420 3.0e-03 0.044 NA 0.018 NA 0.030 2.9e-04 NA 1.5e-02 NA 2.3e-03
4 GTEx Esophagus Mucosa 0.0980 0.0460 1.5e-04 0.048 NA 0.037 NA 0.046 3.6e-04 NA 1.6e-03 NA 4.7e-04
5 GTEx Esophagus Muscularis 0.0550 0.0380 2.3e-03 0.017 NA 0.001 NA 0.016 3.1e-02 NA 2.8e-01 NA 3.6e-02
6 GTEx Skin Sun Exposed Lower leg 0.0820 0.0340 1.1e-06 0.010 NA 0.054 NA 0.048 4.7e-02 NA 2.6e-05 NA 7.8e-05
7 GTEx Thyroid 0.0480 0.0290 1.4e-03 0.033 NA 0.038 NA 0.026 1.4e-03 NA 6.5e-04 NA 4.1e-03
8 NTR Blood 0.0107 0.0073 5.1e-04 0.010 0.011 0.012 0.010 0.011 1.9e-04 1.5e-04 6.1e-05 2.5e-04 1.5e-04
9 ROSMAP Brain Pre-frontal Cortex 0.0193 0.0140 4.8e-03 0.005 0.016 0.009 0.016 0.011 6.7e-02 3.7e-03 2.0e-02 2.9e-03 1.2e-02
10 TCGA Breast Invasive Carcinoma 0.0316 0.0172 2.5e-06 0.021 0.018 0.018 NA 0.013 3.0e-05 1.1e-04 8.5e-05 NA 8.7e-04
11 TCGA Glioblastoma Multiforme 0.1280 0.0920 6.1e-03 0.012 0.038 0.005 NA 0.024 1.4e-01 2.6e-02 2.2e-01 NA 6.2e-02
12 TCGA Brain Lower Grade Glioma 0.0706 0.0385 1.8e-05 0.037 0.041 0.045 NA 0.046 4.5e-05 1.6e-05 6.9e-06 NA 5.0e-06
13 TCGA Ovarian Serous Cystadenocarcinoma 0.0620 0.0400 9.9e-04 0.042 0.024 0.034 NA 0.029 7.5e-04 9.0e-03 2.3e-03 NA 4.2e-03
14 TCGA Soft Tissue Sarcoma 0.0890 0.0560 4.3e-03 0.033 0.030 0.028 NA 0.017 4.5e-03 6.8e-03 8.4e-03 NA 3.4e-02
15 TCGA Thyroid Carcinoma 0.1130 0.0530 2.8e-05 0.050 0.071 0.070 NA 0.056 1.2e-05 1.8e-07 2.1e-07 NA 3.6e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 1.7 2.8 11.6 1.6 -0.5 2.0 -3.4 1.7 -2.1 -1.1 1.0 0.6 -0.8 0.3 1.9 -1.3 -2.6 -0.3
Bipolar Disorder or Schizophrenia 0.8 1.9 6.8 0.5 -0.9 1.6 -2.3 0.6 -2.1 -1.3 0.0 -0.3 -1.5 -0.6 1.1 -1.4 -2.6 -0.8
Depressed Affect (Nagel 2018) 0.4 0.9 2.9 0.2 -1.4 1.1 -0.7 -0.0 -1.7 -1.3 -0.1 -0.4 -1.4 -0.9 0.8 -0.6 -1.1 0.8
Depression (Nagel 2018) 0.9 1.3 6.1 -1.2 -1.5 0.1 0.1 -0.9 -1.1 -0.7 0.1 0.2 -2.2 -1.6 -0.0 -0.3 -2.5 -0.4
Intelligence (Savage-Jansen 2018) 0.9 2.7 6.4 2.5 1.0 1.7 -1.8 2.5 -0.2 0.9 1.9 1.4 1.5 1.8 2.3 0.5 0.1 1.7
Neuroticism (Nagel 2018) 0.3 0.6 2.1 0.2 -0.8 0.9 -1.2 0.2 -1.2 -0.6 0.3 0.4 -1.1 -0.2 0.8 0.1 -1.4 0.5
Schizophrenia (2018) 0.3 0.6 1.7 -0.7 -0.8 0.4 -0.3 -0.6 -0.8 -0.7 -0.7 -0.8 -1.3 -1.1 -0.1 -0.7 -1.3 -0.8
Schizophrenia vs Biploar Disorder 1.3 1.8 4.6 -1.5 0.4 -1.7 2.1 -1.6 1.4 0.4 -1.3 -1.3 0.4 -0.5 -2.0 0.4 1.8 -0.9
Worry (Nagel 2018) 0.1 0.3 0.9 -0.2 -0.8 0.4 -0.4 -0.2 -0.8 -0.7 -0.4 -0.2 -0.9 -0.4 0.2 -0.2 -0.9 -0.0
Alzheimer’s Disease (in mother) 0.7 0.8 2.7 -1.2 -0.6 -0.7 -0.2 -1.1 -0.2 -0.1 -0.6 -0.4 -1.4 -1.0 -0.8 -0.3 -1.5 -1.6
Alzheimer’s Disease (in father) 0.1 0.1 0.3 -0.0 0.2 -0.1 -0.0 0.2 0.1 0.2 0.6 0.5 -0.0 -0.1 0.2 -0.1 -0.4 -0.2
Alzheimer’s Disease (including proxy) 0.2 0.3 0.9 -0.9 -0.4 -1.0 0.6 -0.6 0.6 0.6 -0.0 0.4 -0.1 -0.5 -0.6 0.2 -0.4 -0.8
Crohns Disease (2017) 0.7 1.6 3.7 -1.1 -1.5 -0.2 0.2 -1.2 -0.8 -1.4 -1.9 -1.2 -1.9 -1.5 -1.0 -1.1 -1.4 -1.3
Irritable Bowel Disease (IBD) 1.4 3.3 7.2 -1.0 -2.6 0.8 -0.5 -1.1 -2.1 -2.2 -1.7 -2.0 -2.7 -2.3 -0.4 -2.2 -2.2 -1.1
Ulcerative Colitis (UC) 1.9 3.6 7.4 -0.8 -2.7 1.1 -0.9 -1.0 -2.4 -2.3 -1.3 -2.3 -2.6 -2.3 -0.2 -2.6 -2.1 -1.1
Major Depression (MDD) 0.4 0.5 1.5 0.2 0.6 -0.2 -0.7 0.4 0.3 0.9 1.1 1.2 -0.1 0.7 0.7 1.0 -1.2 -0.1
Reaction Time 0.7 1.3 6.0 0.7 -1.6 1.7 0.2 0.6 -1.7 -1.0 -0.1 -0.1 -1.1 -0.8 1.4 -0.3 -0.6 2.4
Verbal and Numeric Reasoning (VNR) 3.2 7.7 16.9 4.0 1.6 3.1 -3.3 4.1 -0.7 1.4 3.3 2.5 2.2 2.9 4.0 1.1 -0.1 3.0
Breast Cancer 0.3 0.7 2.4 -0.1 -1.2 0.5 1.6 -0.2 -0.4 -0.7 -0.5 -0.9 -0.5 -1.0 -0.0 -0.4 0.8 1.3
Ovarian Cancer 0.8 1.0 3.3 -0.5 1.4 -1.4 0.5 -0.1 1.3 1.3 0.8 1.4 0.7 0.9 -0.4 1.8 0.7 0.2
Prostate Cancer 0.4 0.5 1.8 0.6 0.4 0.3 -0.6 0.9 -0.1 0.6 0.5 1.0 0.2 0.8 0.8 1.1 -0.2 1.3
Age at First Birth 0.3 0.5 3.1 0.8 0.0 0.8 -1.8 0.4 -0.9 -0.9 0.5 -0.1 -0.1 0.5 0.5 -0.4 -0.6 -0.1
Bipolar Disorder (2011) 1.9 1.8 4.7 1.8 0.4 1.6 -1.9 1.8 -0.9 0.2 2.2 1.1 0.3 1.1 2.0 0.0 -1.0 1.0
Body Mass Index (BMI) (2010) 0.3 0.4 1.8 -0.1 0.7 -0.7 0.1 0.1 0.4 1.1 0.0 1.3 0.3 0.5 0.4 1.0 -0.8 0.0
Coronary Artery Disease (CAD) 1.2 1.4 3.3 -0.4 -1.7 0.7 -0.9 -0.4 -1.4 -1.3 -1.0 -1.2 -1.7 -1.3 -0.1 -1.6 -1.8 -0.9
Crohns Disease (2012) 0.7 1.1 3.0 0.5 -1.3 1.1 -1.0 0.2 -1.5 -1.4 -0.3 -0.9 -1.3 -0.9 0.5 -1.2 -1.7 -0.6
Mean Putamen Volume 0.7 0.8 2.6 -1.1 0.5 -1.6 0.5 -1.0 1.1 0.5 -0.9 -0.2 0.1 0.0 -1.4 0.3 0.5 -1.6
Fasting Glucose 0.2 0.3 1.0 -0.4 0.7 -0.5 0.0 -0.1 0.8 0.1 1.0 0.6 0.4 0.3 -0.4 0.8 0.4 -0.4
HbA1C 1.3 1.4 3.8 -1.0 -1.9 -0.0 -0.5 -1.3 -1.2 -1.2 -1.0 -0.9 -1.8 -1.6 -0.3 -0.8 -2.0 -0.3
HDL Cholesterol 0.6 0.9 2.7 -0.1 -1.1 0.5 -0.3 -0.3 -1.3 -1.4 -1.6 -1.2 -0.9 -1.2 0.1 -1.5 -0.3 0.3
LDL Cholesterol 1.1 1.7 4.9 -1.5 0.6 -2.2 1.1 -1.7 1.4 0.3 -1.9 -0.7 0.2 -0.1 -1.9 0.2 0.9 -1.6
Lupus 1.0 1.5 4.1 1.6 0.6 1.5 -1.7 1.6 -0.7 0.3 2.0 1.0 0.5 1.2 1.8 0.5 -0.7 0.5
Neuroticism (2016) 0.2 0.4 0.8 -0.3 0.7 -0.6 0.5 -0.5 0.7 0.9 -0.3 0.1 0.8 0.7 -0.4 0.8 0.8 -0.1
Primary Biliary Cirrhosis 0.3 0.4 1.8 -0.1 -0.8 0.3 -0.2 -0.0 -0.9 -0.2 -0.6 0.5 -1.0 -0.7 0.4 -0.4 -1.4 0.1
Rheumatoid Arthritis 0.4 0.5 2.5 -0.3 -0.4 0.0 1.3 -0.3 0.2 -0.3 -0.5 -0.9 0.3 -0.5 -0.5 -0.4 1.6 0.9
Schizophrenia (2014) 0.1 0.1 0.3 0.1 -0.3 0.5 -0.1 0.0 -0.6 -0.3 -0.3 -0.5 -0.4 -0.4 0.3 -0.5 -0.4 0.1
Triglycerides 0.8 1.3 4.0 1.1 0.5 0.7 -2.0 1.2 -0.6 0.7 1.3 1.4 0.0 1.0 1.6 0.7 -1.9 0.1
Type 2 Diabetes (T2D) (2012) 0.8 0.9 2.7 1.5 0.4 1.0 -0.4 1.2 -0.5 -0.1 1.0 0.2 0.8 0.9 1.3 0.2 0.9 1.6
Ulcerative Colitis 0.8 1.2 2.4 -0.4 -1.4 0.8 -0.9 -0.3 -1.6 -1.4 -0.8 -0.9 -1.5 -1.3 0.3 -1.5 -1.6 -0.7
Blood Eosinophil Count 0.4 3.2 8.5 -1.6 1.7 -2.5 2.7 -0.7 2.8 2.4 0.7 1.9 0.8 0.3 -0.9 2.9 0.7 0.5
Blood Platelet Count 0.3 3.7 18.7 -2.4 -0.8 -1.9 4.3 -2.2 1.6 0.3 -2.1 -1.3 -0.3 -1.9 -2.4 -0.1 1.9 0.3
Blood Red Count 0.3 2.8 6.7 1.3 2.5 -0.2 -0.4 1.5 1.4 1.6 1.9 1.6 2.6 2.3 0.8 1.8 1.9 0.9
Blood White Count 3.6 26.4 53.3 -7.0 -5.2 -3.7 3.9 -6.6 -1.4 -3.1 -6.0 -3.4 -7.3 -7.1 -5.0 -2.8 -5.4 -4.7
Heel T-Score 0.5 4.2 10.4 2.7 -0.6 3.1 -2.5 2.6 -2.5 -0.7 1.1 1.0 -0.4 0.6 3.2 -0.3 -1.8 2.9
BMI 0.4 2.5 7.5 -2.2 1.4 -2.7 1.1 -1.4 2.0 1.7 0.1 1.6 -0.2 0.3 -1.6 2.1 -0.5 -1.9
Height 1.2 23.9 65.9 -6.6 1.5 -7.9 5.2 -6.5 5.6 1.1 -3.0 -2.8 0.3 -1.7 -8.1 0.7 3.9 -6.9
Waist Hip Ratio (WHR) 0.2 0.7 3.2 -0.4 -0.9 0.3 1.8 -0.5 -0.6 -0.7 -0.3 -1.3 -0.3 -1.3 -0.2 -0.7 0.6 1.1
Systolic Blood Pressure 0.2 1.1 2.9 -1.0 0.7 -1.7 1.3 -1.0 1.4 0.6 -0.8 -0.6 0.8 -0.2 -1.6 0.0 1.7 -0.8
Smoking Status 0.2 0.5 2.3 -0.5 0.9 -1.0 0.3 -0.0 1.0 1.1 -0.1 1.5 0.3 0.4 -0.2 0.9 -0.6 -0.3
Allergy or Eczema 1.5 4.0 8.5 -0.1 -2.9 1.6 -1.3 -0.6 -2.9 -2.9 -1.8 -2.1 -2.5 -2.3 0.4 -2.7 -2.1 -0.2
Cardiovascular Disease 0.1 0.2 1.3 -0.4 -0.4 -0.3 -0.1 -0.4 -0.3 -0.2 -1.2 -0.3 -0.6 -0.5 -0.3 -0.5 -0.6 -0.5
Hypothyroidism (self reported) 0.4 0.9 2.4 -0.8 0.9 -1.3 1.3 -0.3 1.4 1.5 -0.1 1.4 0.5 0.3 -0.4 1.3 -0.0 0.1
Respiratory disease 0.1 0.2 0.6 -0.6 -0.1 -0.7 0.6 -0.4 0.1 0.4 -0.6 0.6 -0.5 -0.5 -0.2 0.3 -0.8 -0.4
Type 2 Diabetes (T2D) (2018) 2.5 4.6 9.8 -3.1 -1.8 -2.0 1.7 -3.1 -0.1 -1.3 -2.9 -1.7 -2.6 -2.6 -2.6 -0.7 -1.2 -2.2
Lung FEV1/FVC ratio 0.9 4.5 14.2 -3.2 1.3 -3.8 2.2 -2.5 2.7 1.6 -0.7 0.7 -0.3 -0.4 -2.9 1.8 0.3 -2.6
Lung FVC 1.5 7.5 23.2 4.1 0.3 3.8 -4.8 3.8 -2.5 -0.7 2.7 1.2 0.9 2.1 3.9 -0.5 -1.1 2.5
Neuroticism 0.1 0.3 0.7 0.3 -0.3 0.7 -0.9 0.3 -0.8 -0.4 0.6 0.4 -0.4 0.1 0.8 0.1 -0.7 0.3
Chronotype (morning person) 0.3 0.6 1.4 -1.0 0.6 -1.1 1.2 -0.7 0.9 1.1 -1.0 0.6 -0.1 0.0 -0.7 1.1 -0.3 -0.0
Hair Pigment 0.0 1.3 3.3 1.4 -0.1 1.6 -1.3 1.6 -1.0 -0.0 1.5 1.0 -0.1 0.5 1.8 0.3 -0.7 1.6
Tanning 0.1 1.7 4.3 1.8 0.5 1.6 -2.0 1.8 -0.7 0.1 2.1 1.2 0.5 1.3 1.8 0.5 -0.7 0.7
Hand grip strength (left) 0.9 2.2 6.7 -0.6 2.2 -2.0 0.2 -0.4 2.6 1.7 0.4 0.7 1.7 1.4 -1.3 1.2 1.4 -2.0
Number of treatments/medications taken 1.1 1.9 5.6 -1.1 -1.7 -0.3 -0.8 -1.3 -1.6 -1.4 -2.3 -0.9 -2.4 -1.3 -0.6 -0.7 -1.9 -0.8
Average weekly spirits intake 1.0 1.3 2.7 -1.6 -0.5 -1.4 1.4 -1.6 0.4 -0.0 -1.6 -1.0 -0.9 -1.0 -1.5 -0.2 -0.3 -1.4
Sensitivity / hurt feelings 0.2 0.3 1.1 -1.0 0.2 -1.1 0.3 -0.8 0.5 0.3 0.1 0.6 -0.4 -0.1 -0.7 0.6 -0.3 -0.4
Frequency of depressed mood in last 2 weeks 0.7 0.9 3.5 -0.7 -1.4 0.5 -0.1 -0.5 -1.2 -0.7 0.7 0.1 -1.8 -1.2 0.3 -0.3 -1.9 0.1
Hearing difficulty/problems: Yes 1.9 3.0 8.4 1.4 1.4 0.9 -1.9 1.9 -0.1 1.4 2.6 2.9 0.7 2.1 2.0 2.1 -0.7 1.4
Relative age of first facial hair 2.2 4.5 11.4 1.2 -2.3 2.5 -3.0 0.7 -3.4 -2.7 -0.1 -1.3 -2.2 -1.3 1.5 -2.6 -3.0 -0.6
Other serious medical condition/disability diagnosed by doctor 2.1 2.7 5.5 2.1 0.9 1.6 -1.9 2.3 -0.5 0.9 1.7 2.1 1.0 1.9 2.3 1.2 -0.2 2.2
Ever used hormone-replacement therapy (HRT) 1.0 1.3 3.2 0.5 1.4 -0.3 -0.1 0.8 1.0 1.7 1.5 1.8 0.9 1.3 0.7 1.7 0.3 0.9
Ever had hysterectomy (womb removed) 0.6 0.7 2.4 1.1 -0.4 1.6 -0.5 1.0 -0.8 -0.1 0.8 0.1 0.0 0.2 1.3 -0.1 -0.1 1.5
Systolic blood pressure, automated reading 0.2 0.5 1.8 -0.7 0.5 -1.4 0.3 -0.7 1.2 0.6 0.2 -0.4 0.3 0.1 -1.1 0.1 0.6 -1.2
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 2.5 -1.6 -0.4 -1.2 1.0 -1.5 0.3 -0.4 -1.1 -0.8 -0.9 -0.9 -1.4 0.3 -0.1 -0.7
Angina 0.5 0.7 1.7 0.3 0.4 0.2 -1.1 0.6 -0.2 0.8 1.3 1.3 -0.3 0.8 0.8 1.1 -1.2 -0.0
Medication for hormone replacement therapy 0.6 0.6 3.0 0.1 0.7 -0.3 -1.7 0.2 0.1 0.8 -0.2 0.8 -0.3 0.9 0.2 0.6 -1.3 -1.1
Vitamin and mineral supplements 0.1 0.1 0.6 0.1 -0.0 0.2 0.1 0.3 0.0 0.2 0.5 0.2 -0.3 -0.3 0.4 0.2 -0.7 0.1
Supplements: Zinc 1.1 1.2 2.6 1.3 1.0 0.7 -0.2 1.4 0.2 0.8 1.5 1.0 1.3 1.3 1.1 1.0 1.1 1.6
Medication: Co-codamol 1.8 2.1 4.4 1.6 1.4 0.8 -1.0 1.8 0.5 1.4 2.1 1.9 1.3 1.8 1.7 1.5 0.1 1.4
Medication: Metformin 1.7 2.5 5.9 -2.1 -1.4 -1.4 1.6 -2.2 -0.1 -1.2 -2.4 -1.4 -1.6 -1.8 -2.0 -0.7 -0.2 -1.1
Diabetes (father) 0.5 0.6 1.9 -0.5 -0.8 -0.1 0.0 -0.7 -0.3 -1.0 -1.1 -1.4 -0.5 -1.0 -0.7 -0.9 0.2 -0.4
Diabetes (mother) 0.1 0.2 0.6 0.3 0.5 -0.1 -0.4 0.4 0.2 0.5 -0.2 0.6 0.5 0.7 0.2 0.4 0.0 0.4
Severe depression (siblings) 0.8 0.8 2.1 0.7 -1.1 1.4 -1.3 0.4 -1.3 -0.9 0.4 -0.6 -1.0 -0.5 1.0 -0.7 -1.1 0.4
Pack years adult smoking proportion 0.7 1.1 3.1 1.2 -0.5 1.5 -1.8 1.1 -1.5 -0.7 0.3 0.1 -0.4 0.1 1.4 -0.7 -1.2 0.6
Impedance of leg (right) 0.5 2.4 7.6 -1.9 -1.3 -1.2 1.3 -2.1 -0.1 -1.1 -2.8 -1.8 -1.4 -1.9 -1.9 -1.1 -0.1 -1.1
Leg fat-free mass (left) 1.2 6.4 19.4 -3.3 1.7 -4.4 2.0 -2.8 3.4 1.7 -0.5 0.2 0.4 0.1 -3.7 1.5 1.2 -4.2
Trunk fat percentage 1.4 5.4 16.5 -3.7 0.8 -4.1 1.7 -3.1 2.3 1.3 -1.1 0.4 -1.2 -0.7 -3.2 2.0 -0.7 -3.5
Hand grip strength (right) 0.6 1.7 5.3 -0.3 2.1 -1.6 -0.0 -0.2 2.3 1.6 0.6 0.9 1.6 1.2 -0.9 1.0 1.0 -1.8
Townsend deprivation index at recruitment 0.2 0.3 1.2 -0.7 -0.6 -0.1 0.8 -0.5 -0.3 0.2 -0.0 0.0 -0.9 -0.9 -0.1 0.2 -1.1 0.1
Current tobacco smoking 0.1 0.1 0.3 -0.2 0.4 -0.5 0.3 -0.1 0.6 0.2 -0.2 0.1 0.2 0.1 -0.3 0.4 0.2 0.2
Average weekly fortified wine intake 1.1 1.3 2.9 1.5 0.9 0.8 -0.8 1.7 0.2 1.0 1.6 1.3 1.1 1.2 1.5 0.7 -0.2 1.2
Maternal smoking around birth 0.9 1.2 3.6 -1.6 0.8 -1.9 0.9 -1.0 1.3 1.5 -0.4 1.3 -0.4 -0.1 -1.0 1.2 -0.9 -1.0
Fed-up feelings 0.4 0.8 2.4 0.4 -1.3 1.2 -0.4 0.2 -1.6 -1.0 -0.6 -0.7 -1.1 -0.5 0.9 -0.4 -0.8 1.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 3.6 -1.3 -1.3 -0.3 1.2 -1.0 -0.8 -0.3 -0.2 0.3 -1.9 -1.4 -0.2 0.3 -1.8 0.3
Relative age voice broke 0.3 0.5 1.6 0.8 -0.4 1.1 -1.3 0.7 -1.1 -0.2 -0.0 0.6 -0.4 0.1 0.9 -0.5 -0.9 0.4
Taking other prescription medications 4.1 6.3 16.0 0.2 -3.6 2.3 -1.8 -0.3 -4.0 -3.1 -1.9 -1.8 -3.6 -2.6 1.1 -2.7 -3.6 0.5
Age when periods started (menarche) 0.1 0.2 0.7 0.4 -0.3 0.6 -0.2 0.1 -0.5 -0.7 0.4 -0.8 0.2 -0.2 0.2 -0.8 0.6 0.4
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.8 -0.1 0.6 -0.0 0.3 0.1 0.4 0.9 1.2 1.0 0.0 0.5 0.4 1.4 -0.1 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.2 0.8 -0.1 0.7 -1.1 0.7 -0.7 -0.0 0.6 0.3 0.0 0.4 0.7 -0.5 -0.5 0.1
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.3 -0.3 -0.5 0.2 0.5 -0.3 -0.1 0.1 -0.4 -0.4 -0.4 -0.3 -0.2 -0.0 0.1 0.1
Qualifications: CSEs or equivalent 0.1 0.1 0.5 -0.2 -0.1 -0.1 0.2 -0.4 -0.1 0.1 -0.7 -0.6 0.1 -0.3 -0.5 -0.6 0.3 -0.3
Serious illness, injury or assault to yourself 0.5 0.6 1.7 0.5 0.6 0.1 -0.8 0.7 0.1 0.8 0.8 1.0 0.2 1.0 0.6 1.3 0.2 1.0
High blood pressure 0.3 0.8 1.7 -0.4 -1.2 0.0 -0.6 -0.6 -1.1 -1.3 -1.3 -0.8 -1.2 -0.9 -0.3 -1.0 -1.0 -0.5
Hayfever, allergic rhinitis or eczema 1.2 2.6 5.3 -0.4 -2.3 0.9 -0.3 -0.9 -2.0 -2.3 -2.1 -2.0 -1.9 -2.2 -0.1 -2.2 -1.2 -0.3
Multivitamins +/- minerals 0.2 0.3 0.8 0.7 -0.2 0.9 -0.4 0.5 -0.7 -0.3 0.4 0.2 0.3 0.3 0.6 -0.4 0.4 0.8
Stomach or abdominal pain in last month 0.1 0.2 0.6 -0.2 0.2 -0.5 0.6 -0.3 0.7 0.0 0.4 0.0 0.3 0.2 -0.4 0.3 0.8 0.2
Supplements: Glucosamine 0.6 0.7 2.3 -0.5 1.1 -1.2 0.2 -0.6 1.3 0.3 -0.0 -0.2 0.9 0.8 -1.1 0.6 1.5 -0.9
Diverticular disease/diverticulitis (self-reported) 0.0 0.0 0.2 0.0 -0.0 0.0 -0.1 0.1 -0.1 -0.2 -0.2 -0.0 -0.2 0.1 0.1 0.4 -0.3 0.2
Medication: Atenolol 0.3 0.4 0.9 -0.4 -0.8 0.1 -0.2 -0.4 -1.0 -0.9 -0.1 -0.5 -0.9 -0.5 -0.1 -0.5 -0.9 -0.8
Medication: Levothyroxine sodium 0.8 1.3 3.6 -0.5 1.3 -1.2 1.2 -0.3 1.6 1.3 -0.1 0.7 1.3 1.0 -0.8 1.5 1.9 0.5
Sitting height 0.7 5.2 16.6 -2.6 2.1 -4.1 1.0 -2.2 3.4 1.9 -0.4 0.7 0.8 0.6 -3.2 1.4 1.2 -3.6
Chronic bronchitis/emphysema (father) 1.4 1.7 4.8 1.9 -0.5 2.0 -0.8 1.6 -1.1 -0.6 1.7 0.4 0.4 0.3 2.1 -0.1 0.0 2.2
High blood pressure (mother) 0.2 0.3 0.9 0.1 -0.2 0.0 -0.6 -0.2 -0.2 -0.7 -0.1 -0.9 0.2 -0.1 -0.5 -1.0 0.7 -0.7
Body mass index (BMI) 0.3 1.1 3.2 -1.1 1.1 -1.8 0.4 -0.7 1.4 1.2 0.6 1.1 0.2 0.5 -0.9 1.4 -0.0 -1.4
Impedance of leg (left) 0.3 1.7 5.8 -1.5 -0.9 -1.0 1.8 -1.7 0.3 -0.6 -2.4 -1.5 -0.8 -1.4 -1.6 -0.6 0.6 -0.3
Leg predicted mass (left) 1.2 6.6 20.1 -3.3 1.8 -4.5 2.0 -2.9 3.5 1.8 -0.5 0.2 0.5 0.1 -3.8 1.6 1.3 -4.2
Trunk fat mass 1.7 7.1 22.0 -4.1 1.1 -4.7 2.2 -3.5 3.0 1.5 -1.3 0.2 -0.8 -0.6 -3.9 1.9 0.2 -4.0
Waist circumference 0.8 3.0 8.9 -2.7 0.6 -3.0 2.2 -2.3 1.9 0.7 -0.7 -0.4 -0.2 -0.8 -2.6 0.9 0.7 -2.3
Number of incorrect matches in round 0.0 0.1 0.2 -0.3 0.2 -0.4 -0.1 -0.4 0.3 0.3 0.4 -0.0 -0.1 -0.1 -0.5 0.3 0.2 -0.2
Past tobacco smoking 0.3 0.5 2.5 -0.5 -0.1 -0.4 0.7 -0.8 0.3 -0.4 -0.5 -1.6 0.2 -0.3 -1.0 -0.2 1.2 -0.5
Alcohol usually taken with meals 1.7 2.7 6.8 2.5 0.6 2.1 -2.6 2.3 -1.1 -0.5 2.1 0.6 1.2 1.7 2.1 -0.1 0.2 1.1
Nervous feelings 0.1 0.2 0.8 0.4 0.2 0.3 -0.9 0.5 -0.2 0.3 0.7 0.7 -0.0 0.5 0.6 0.4 -0.7 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.0 -0.1 -0.2 0.5 -0.6 0.3 -0.6 0.4 1.1 1.3 -1.0 0.1 1.0 1.4 -1.4 1.2
Hearing difficulty/problems with background noise 1.0 1.7 5.2 0.5 0.5 0.5 -1.3 1.0 -0.5 0.9 1.7 2.3 -0.5 1.0 1.5 2.1 -1.8 1.0
Hair/balding pattern: Pattern 2 0.0 0.1 0.3 0.1 -0.1 0.0 0.0 0.0 -0.2 -0.0 0.1 -0.0 -0.1 -0.3 0.2 -0.4 -0.4 -0.5
Had menopause 1.0 1.2 3.4 0.6 -1.6 1.5 -0.1 0.3 -1.8 -1.3 0.4 -0.5 -1.2 -1.0 1.2 -0.7 -1.2 1.4
Had other major operations 0.3 0.4 1.1 0.6 -0.4 0.8 -1.0 0.7 -0.7 -0.3 1.0 0.2 -0.4 -0.2 0.9 -0.4 -0.8 0.3
Forced vital capacity (FVC) 0.4 1.5 9.1 -1.4 0.6 -1.9 -0.8 -1.3 0.9 0.2 -1.1 -0.4 -0.3 0.0 -1.8 -0.3 -0.4 -3.0
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 1.9 0.9 -0.4 1.1 -1.4 0.9 -1.1 -0.2 0.5 0.4 -0.3 0.2 1.0 -0.7 -1.1 0.3
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 0.6 0.0 -0.5 0.4 -0.4 0.0 -0.5 -0.3 0.8 -0.0 -0.5 -0.3 0.3 -0.3 -0.7 -0.2
Qualifications: None of the above 1.1 2.4 10.6 -2.1 -1.4 -1.1 3.2 -2.1 0.2 -0.5 -1.4 -1.4 -1.1 -2.0 -1.7 -0.4 0.6 0.2
Financial difficulties in last 2 years 1.6 2.2 8.1 -0.6 1.8 -1.4 -0.4 0.1 1.8 2.8 1.0 2.1 0.3 1.4 0.0 2.8 -0.9 -0.4
Mouth/teeth dental problems 1.9 3.0 6.2 -1.8 -1.9 -0.5 1.1 -2.0 -0.9 -1.8 -2.2 -2.5 -1.7 -2.1 -1.8 -1.9 -0.4 -1.7
Heart attack 0.2 0.3 1.1 -0.0 -0.1 0.4 -0.4 0.2 -0.6 0.2 0.2 0.8 -0.6 0.2 0.5 0.7 -1.1 0.2
Allergy 0.4 1.0 2.4 -0.4 1.4 -1.0 0.1 0.0 1.5 1.5 1.1 1.1 0.8 1.2 -0.5 1.3 0.4 -0.7
Pain all over the body in last month 0.3 0.3 1.0 -0.3 -0.6 0.0 0.5 -0.5 -0.2 -0.7 -0.5 -1.0 -0.1 -0.6 -0.6 -0.8 0.9 0.1
Diabetes (self-reported) 0.7 1.1 3.6 -1.8 -0.6 -1.3 1.9 -1.5 0.5 -0.1 -1.0 -0.2 -1.0 -1.2 -1.3 0.5 -0.2 -0.5
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 1.6 0.7 -0.9 1.1 -0.6 0.4 -1.2 -0.9 -0.0 -0.7 -0.4 -0.7 0.7 -1.2 -0.3 0.4
Medication: Ramipril 4.0 5.1 11.9 -2.3 -2.7 -0.6 0.0 -2.4 -1.8 -2.3 -2.2 -1.9 -3.5 -3.0 -1.5 -2.0 -2.9 -2.2
Medication: Simvastatin 4.0 5.8 10.4 -2.4 -2.9 -0.8 0.5 -2.7 -1.6 -2.7 -3.0 -2.5 -3.2 -3.2 -2.1 -2.6 -1.8 -2.2
Fluid intelligence score 1.7 3.5 9.2 2.8 0.5 2.5 -3.0 2.8 -1.1 0.4 1.6 1.3 0.8 1.7 2.9 0.2 -0.9 1.4
Illnesses of siblings 0.2 0.3 1.4 -0.4 0.2 -0.2 1.2 -0.2 0.6 0.9 0.4 0.5 0.0 -0.1 0.0 0.4 -0.3 -0.2
Neuroticism score 0.1 0.2 1.1 0.1 0.0 0.2 -1.1 0.2 -0.5 -0.1 0.7 0.8 -0.3 0.3 0.5 0.3 -0.7 0.1
Weight 1.3 6.6 20.7 -3.6 1.4 -4.5 2.2 -3.1 3.2 1.4 -0.8 0.0 0.0 -0.3 -3.9 1.4 0.9 -4.2
Impedance of arm (right) 0.9 4.0 10.2 -2.9 -0.9 -2.1 0.1 -2.6 0.0 -0.1 -2.4 -0.6 -2.6 -1.8 -2.2 -0.3 -2.7 -3.2
Arm fat percentage (right) 0.8 3.1 9.5 -2.7 0.9 -3.1 0.6 -2.1 1.7 1.4 -0.3 0.9 -0.9 -0.2 -2.1 1.5 -1.1 -3.0
Trunk fat-free mass 0.8 4.4 11.4 -2.3 1.4 -3.4 2.0 -2.2 3.0 0.9 -0.4 -0.8 1.2 0.1 -3.3 0.4 2.5 -3.2
Hip circumference 1.0 4.2 13.7 -2.9 1.1 -3.7 1.5 -2.5 2.6 1.2 -0.8 0.2 -0.1 -0.2 -3.1 1.3 0.6 -3.4
Time employed in main current job 1.3 1.5 4.6 -0.1 -1.5 0.6 2.1 -0.5 -1.0 -1.6 -0.8 -1.5 -0.1 -1.2 -0.1 -1.0 1.7 1.9
Alcohol intake versus 10 years previously 0.6 0.9 3.3 0.9 0.5 1.0 -1.8 1.0 -0.5 0.4 0.8 0.7 -0.1 0.9 1.3 0.7 -1.4 0.3
Father’s age at death 0.2 0.3 0.9 0.0 0.4 -0.5 1.0 -0.0 0.8 0.6 -0.5 0.0 0.7 0.4 -0.3 0.4 0.9 0.5
Worrier / anxious feelings 0.5 0.9 3.7 -0.6 -1.1 0.1 -0.9 -0.6 -1.2 -0.8 -0.3 0.3 -1.7 -0.8 0.1 -0.4 -1.9 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 1.7 -1.3 0.2 -1.2 1.3 -0.8 0.7 0.9 0.1 1.1 -0.6 -0.3 -0.7 1.2 -0.6 0.1
Falls in the last year 0.1 0.2 0.7 -0.2 -0.2 -0.0 -0.2 0.0 -0.1 0.3 0.4 0.4 -0.5 -0.0 0.4 0.7 -0.9 0.6
Hair/balding pattern: Pattern 3 1.9 2.9 7.3 -2.1 -0.4 -2.1 0.5 -2.2 0.8 -1.0 -2.4 -1.9 -0.6 -1.3 -2.7 -1.2 0.4 -2.6
Number of live births 1.1 1.6 7.2 -1.8 -0.8 -1.3 2.7 -1.7 0.4 0.0 -1.4 -0.7 -0.8 -1.6 -1.4 -0.1 0.3 -0.4
Forced expiratory volume in 1-second (FEV1) 0.6 2.2 12.7 -1.8 0.4 -2.1 -0.9 -1.7 0.8 -0.0 -1.3 -0.5 -0.7 -0.3 -2.2 -0.5 -0.7 -3.6
Pulse rate 1.8 3.0 8.9 -2.0 -1.1 -1.4 3.0 -2.2 0.6 -0.8 -2.1 -2.1 -0.8 -2.2 -2.2 -1.3 0.8 -1.3
Happiness 3.2 3.9 13.5 2.7 0.1 2.6 -1.0 2.6 -1.1 0.3 2.6 1.4 1.1 1.3 2.8 0.6 0.9 3.7
Noisy workplace 0.1 0.2 1.2 -0.2 0.0 -0.0 1.1 0.0 0.4 0.4 0.6 0.3 0.1 -0.1 0.1 0.5 0.1 0.6
Qualifications: A levels/AS levels or equivalent 1.0 2.1 6.2 2.1 -0.9 2.5 -2.2 1.7 -1.8 -1.3 1.3 -0.7 0.0 0.4 1.8 -1.2 -0.1 1.0
Serious illness, injury or assault of a close relative in last 2 years 3.0 3.4 9.7 2.3 0.8 1.9 -1.1 2.4 -0.4 1.3 2.5 1.9 1.0 1.6 2.6 1.7 -0.0 3.1
Mouth/teeth dental problems: Dentures 3.9 6.6 12.2 3.3 2.1 2.0 -2.1 3.5 0.0 1.6 3.3 2.8 2.4 3.0 3.3 2.0 0.6 3.3
Asthma 0.3 0.6 1.5 0.5 -1.1 1.0 -0.1 0.3 -1.2 -0.7 -0.3 -0.3 -0.8 -1.0 0.8 -1.0 -1.1 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 3.3 0.2 0.5 0.1 -1.8 0.5 -0.2 0.4 -0.3 1.4 -0.4 0.5 0.6 0.4 -1.6 -0.5
Medication: Cholesterol lowering 0.3 0.5 1.7 0.1 -1.2 0.8 -0.4 -0.0 -1.3 -0.8 -0.5 -0.3 -1.2 -0.4 0.5 -0.1 -1.0 0.4
Depression (self-reported) 0.7 0.8 2.1 1.0 -0.4 1.2 -1.4 1.1 -1.1 -0.3 -0.1 0.6 -0.5 0.2 1.3 -0.3 -1.5 0.8
Medication: Lansoprazole 0.7 0.8 2.3 -0.9 -1.1 -0.3 0.8 -1.1 -0.4 -1.1 -1.0 -1.5 -0.9 -1.1 -0.9 -0.5 0.1 -0.2
Prospective memory result 1.3 1.6 6.9 -1.4 0.7 -1.8 2.6 -1.2 1.8 1.1 -0.4 0.6 0.4 -0.2 -1.2 1.6 1.1 0.5
Lung cancer (father) 1.8 2.1 4.8 -0.2 1.9 -1.4 1.0 0.2 2.2 2.2 1.1 1.3 1.8 1.4 -0.6 1.7 2.0 0.0
Illnesses of mother 0.4 0.5 1.1 -1.0 -0.4 -0.6 1.0 -1.0 0.2 -0.5 -0.7 -0.8 -0.6 -0.8 -0.9 0.1 0.1 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 3.4 -0.9 0.9 -1.4 -0.7 -0.7 0.9 0.6 -0.3 0.4 0.1 0.5 -1.1 0.4 -0.2 -1.8
Pulse wave Arterial Stiffness index 0.2 0.3 0.8 0.2 0.9 -0.4 -0.5 0.3 0.4 0.3 0.6 0.6 0.6 0.7 -0.1 0.5 0.6 -0.1
Impedance of arm (left) 0.7 3.1 6.8 -2.5 -1.2 -1.6 0.2 -2.2 -0.4 -0.5 -2.2 -0.7 -2.6 -1.8 -1.7 -0.4 -2.6 -2.5
Arm fat mass (right) 1.0 4.2 13.5 -3.0 1.2 -3.7 1.3 -2.4 2.4 1.5 -0.4 0.7 -0.4 -0.1 -2.8 1.6 -0.2 -3.5
Trunk predicted mass 0.8 4.5 11.3 -2.2 1.4 -3.4 2.1 -2.2 3.0 0.9 -0.3 -0.8 1.3 0.2 -3.2 0.5 2.6 -3.1
Standing height 1.5 14.4 39.6 -5.2 1.0 -6.1 3.6 -5.1 4.2 0.9 -2.5 -2.0 -0.1 -1.4 -6.3 0.3 2.2 -6.0
Length of working week for main job 1.4 1.6 3.8 1.7 0.7 1.3 -2.0 1.8 -0.4 0.6 1.8 1.2 0.9 1.4 1.6 0.5 -0.2 0.8
Exposure to tobacco smoke at home 1.2 1.4 3.5 -0.8 -1.7 0.4 0.3 -1.1 -1.2 -1.3 -0.5 -1.6 -1.8 -1.9 -0.5 -1.0 -1.2 -0.7
Breastfed as a baby 2.1 2.6 6.4 2.4 0.3 2.2 -0.7 2.3 -0.5 0.3 2.3 1.0 1.1 1.3 2.5 0.5 0.5 2.5
Tense / ‘highly strung’ 0.2 0.3 1.1 -0.5 -0.5 0.0 -0.7 -0.4 -0.3 -0.2 -0.2 -0.1 -0.9 -0.6 -0.2 -0.6 -1.0 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 2.6 0.3 -1.3 1.0 -0.8 0.2 -1.6 -1.1 -0.1 -0.3 -1.3 -0.9 0.8 -0.7 -1.6 0.6
Hair/balding pattern: Pattern 4 2.6 6.3 19.1 2.8 1.3 2.4 0.5 3.2 0.1 2.0 3.5 2.9 1.9 2.3 3.3 2.4 0.7 4.4
Birth weight of first child 1.1 1.9 10.6 -1.6 -0.5 -1.3 -0.5 -1.7 0.3 -0.4 -1.2 -1.0 -1.3 -1.0 -1.7 -0.9 -1.2 -3.2
Peak expiratory flow (PEF) 0.1 0.3 1.0 0.1 0.8 -0.4 -1.0 0.2 0.4 0.6 0.3 0.6 0.6 0.6 -0.3 -0.0 0.5 -0.7
Pulse wave reflection index 1.8 2.3 6.0 0.2 2.4 -1.3 -1.3 0.6 1.5 1.7 1.7 2.1 1.4 2.1 -0.1 2.1 0.6 -0.3
Ever highly irritable/argumentative for 2 days 0.9 1.1 3.3 -1.6 0.7 -1.8 -0.1 -1.2 1.0 0.6 -0.4 0.5 -0.7 0.0 -1.2 1.4 -0.9 -1.7
Loud music exposure frequency 0.5 0.6 3.1 0.3 0.3 0.3 0.7 0.5 0.4 0.6 1.1 1.1 0.5 0.1 0.6 0.6 0.8 1.8
Qualifications: O levels/GCSEs or equivalent 1.6 2.6 7.3 2.5 -0.6 2.7 -2.5 2.1 -1.9 -1.1 1.2 -0.7 0.3 0.6 2.2 -1.2 -0.4 1.0
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 3.1 -0.6 -0.1 -0.6 -0.7 -0.4 0.1 0.2 0.1 0.2 -0.6 -0.3 -0.4 -0.1 -1.0 -1.8
Blood clot in the leg (DVT) 2.8 3.6 11.0 1.5 1.8 0.2 1.5 1.5 1.6 1.4 2.0 0.9 2.9 2.0 0.9 2.0 3.3 2.6
Medication: Paracetamol 1.3 2.1 5.6 -0.8 -1.7 0.1 -1.1 -0.9 -1.6 -1.6 -2.0 -0.9 -2.4 -1.5 -0.4 -1.4 -2.3 -0.8
Headache pain in last month 0.3 0.5 2.2 0.4 1.1 -0.3 -0.6 0.6 0.5 0.8 0.6 1.5 0.7 0.9 0.4 0.8 -0.0 -0.0
Medication for cholesterol, blood pressure or diabetes 0.1 0.1 0.3 0.1 0.3 -0.1 0.4 0.1 0.5 0.2 0.3 -0.3 0.5 -0.3 -0.1 -0.6 0.3 -0.1
Glaucoma (self-reported) 0.1 0.2 0.6 0.0 -0.6 0.3 -0.0 -0.0 -0.5 -0.5 -0.3 -0.4 -0.4 -0.6 0.1 -0.8 -0.4 -0.2
Gout (self-reported) 0.9 1.2 3.3 0.0 -1.6 1.0 -1.1 -0.2 -1.8 -1.3 -0.1 -1.2 -1.6 -1.1 0.4 -1.2 -1.4 -0.2
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.3 -0.5 0.8 -0.9 0.7 -0.2 1.0 1.1 -0.2 1.0 0.5 0.5 -0.3 1.1 0.3 0.2
Medication: Amlodipine 0.1 0.1 0.4 -0.2 -0.0 -0.1 0.1 -0.1 0.0 0.4 -0.6 -0.5 0.2 -0.3 -0.2 -0.4 -0.1 -0.6
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.1 -0.2 -0.8 0.1 0.3 -0.4 -0.5 -0.6 -0.4 -0.9 -0.5 -0.9 -0.2 -1.1 -0.1 -0.5
Birth weight 1.1 2.4 10.3 -2.2 -0.2 -2.2 -0.0 -2.2 0.9 -0.2 -1.6 -0.9 -1.1 -0.9 -2.3 -0.2 -0.7 -3.2
Chronic bronchitis/emphysema (mother) 2.0 2.3 4.4 -2.0 -1.4 -1.2 1.4 -2.1 -0.0 -0.8 -2.1 -1.2 -1.6 -2.0 -1.7 -1.1 -0.8 -1.6
High blood pressure (siblings) 0.1 0.2 1.0 0.1 -0.1 -0.1 -0.2 -0.1 -0.0 -0.6 -0.3 -0.6 0.3 0.1 -0.4 -0.3 1.0 0.4
Forced vital capacity (FVC), Best measure 0.1 0.4 2.0 -0.1 0.7 -0.5 -1.4 0.0 0.3 0.3 0.1 0.3 0.1 0.6 -0.4 0.1 -0.5 -1.4
Body fat percentage 1.1 4.4 13.7 -3.4 0.8 -3.7 1.8 -2.8 2.2 1.3 -1.0 0.4 -0.9 -0.6 -2.9 1.8 -0.3 -3.0
Leg fat percentage (right) 0.6 2.2 6.8 -2.5 0.3 -2.6 1.6 -2.1 1.4 0.7 -0.8 0.2 -0.7 -0.7 -2.1 1.1 -0.1 -1.8
Arm fat-free mass (right) 0.9 4.4 11.1 -2.3 1.3 -3.3 2.6 -2.2 3.0 0.9 -0.3 -0.6 1.2 0.0 -3.1 0.9 2.8 -2.4
Exposure to tobacco smoke outside home 0.9 1.2 2.9 -0.8 -1.6 0.1 0.6 -1.1 -0.9 -1.4 -1.2 -1.5 -1.4 -1.7 -0.7 -1.1 -0.3 0.1
Comparative body size at age 10 0.3 0.9 2.7 -0.3 -0.7 -0.0 1.6 -0.7 0.0 -0.9 -1.0 -1.6 0.3 -0.8 -0.8 -1.1 1.6 -0.0
Number of full brothers 1.0 1.3 3.0 1.6 1.1 1.0 -1.7 1.6 -0.1 0.6 1.3 1.1 1.2 1.4 1.4 0.2 0.2 0.8
Worry too long after embarrassment 0.4 0.6 1.8 -0.1 1.0 -0.7 -0.6 0.1 0.8 0.9 1.1 1.3 0.5 1.1 0.0 1.0 0.1 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 3.0 0.2 -0.6 0.6 -0.8 0.4 -1.0 -0.3 0.4 0.6 -1.1 -0.3 0.8 0.2 -1.7 0.2
Wheeze or whistling in the chest in last year 0.3 0.6 2.7 0.7 0.1 0.7 0.4 0.8 -0.2 0.5 0.7 0.8 0.3 0.4 1.1 0.9 0.2 1.6
Number of children fathered 1.0 1.1 3.2 1.6 -0.2 1.6 -1.8 1.4 -1.0 -0.6 0.9 -0.0 0.1 0.2 1.5 -0.8 -0.9 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.4 -0.3 -0.5 0.1 0.6 -0.2 0.0 0.1 -0.1 -0.0 -0.6 -0.4 0.1 0.3 -0.4 0.6
Age at first live birth 0.6 1.0 3.0 1.4 -0.3 1.7 -1.1 1.3 -1.0 -0.4 1.3 0.1 -0.0 0.5 1.6 0.0 -0.7 1.2
Pulse wave peak to peak time 0.2 0.2 0.5 -0.3 -0.7 0.1 0.6 -0.4 -0.1 -0.2 -0.7 -0.6 -0.5 -0.6 -0.1 -0.4 -0.4 -0.1
Health satisfaction 0.9 1.1 2.8 -1.7 -1.0 -1.0 1.1 -1.6 -0.0 -0.5 -1.2 -0.6 -1.4 -1.3 -1.3 -0.3 -0.5 -0.8
Shortness of breath walking on level ground 2.5 3.0 8.5 -2.9 0.2 -2.8 2.2 -2.3 1.4 0.7 -1.6 0.5 -1.2 -0.9 -2.2 1.4 -0.6 -1.5
Qualifications: College or University degree 0.6 2.0 5.0 1.7 1.3 0.9 -2.1 1.8 0.2 1.0 2.2 1.5 1.3 1.9 1.4 1.0 0.3 0.7
Eye problems/disorders: None of the above 0.6 0.7 1.4 1.2 0.7 0.9 -0.1 1.2 -0.0 0.4 1.1 0.1 1.1 0.9 0.9 0.2 0.9 1.1
Mouth/teeth dental problems: Loose teeth 1.6 1.9 3.8 1.2 1.4 0.2 0.4 1.3 1.0 1.2 1.6 1.6 2.0 1.5 0.8 1.1 2.0 1.8
Emphysema/chronic bronchitis 0.7 0.8 2.8 -1.3 0.1 -1.3 1.7 -1.1 0.5 0.2 -1.3 0.2 -0.2 -0.5 -1.1 0.4 0.4 -0.2
Medication for pain relief, constipation, heartburn 1.8 3.0 8.8 0.3 2.5 -1.2 1.3 0.5 2.6 1.9 1.5 0.6 2.9 1.7 -0.6 1.3 3.0 -0.3
Neck or shoulder pain in last month 0.3 0.4 2.3 -0.3 0.8 -0.5 -0.4 0.0 0.6 0.9 0.5 1.1 0.0 0.6 0.0 1.5 -0.2 0.3
Medication: Blood pressure 0.4 0.6 1.8 -0.3 -0.8 0.1 -1.3 -0.5 -1.1 -1.2 -1.1 -0.6 -1.0 -0.2 -0.4 -0.6 -0.7 -0.7
Angina (self-reported) 0.5 0.6 1.8 0.3 0.3 0.3 -1.2 0.6 -0.3 0.7 1.3 1.2 -0.3 0.8 0.9 1.0 -1.1 0.0
Migraine (self-reported) 2.3 2.9 6.9 2.3 0.4 2.2 -2.6 2.3 -1.4 0.6 1.5 1.3 0.2 1.6 2.6 1.0 -1.2 1.7
Medication: Ibuprofen 0.4 0.5 3.4 -0.3 -0.1 -0.0 -1.1 0.1 -0.4 0.3 -0.6 1.0 -0.9 -0.2 0.3 0.2 -1.8 -0.6
Medication: Allopurinol 0.8 1.1 2.7 -0.6 -1.3 0.1 -1.2 -0.7 -1.2 -1.2 -0.5 -1.1 -1.6 -1.0 -0.3 -0.9 -1.6 -1.1
Medication: Omeprazole 3.4 4.0 7.1 -1.1 -2.4 0.2 -1.1 -1.6 -2.0 -2.4 -1.7 -2.5 -2.7 -2.3 -0.9 -2.6 -2.2 -2.4
Medication: Seretide 50 evohaler 0.6 0.7 3.6 -0.5 0.1 -0.7 1.9 -0.8 0.9 0.4 -0.7 -0.4 0.6 -0.3 -0.7 0.1 1.6 0.2
Mean time to correctly identify matches 1.0 1.9 9.3 0.9 -1.9 1.9 0.7 0.6 -1.9 -1.3 0.1 -0.4 -1.1 -1.0 1.6 -0.4 -0.3 3.0
Heart disease (mother) 0.7 0.9 3.2 1.2 0.0 1.4 -1.8 1.2 -1.1 -0.4 0.7 0.4 0.1 0.6 1.3 -0.0 -0.5 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 2.5 0.0 0.7 -0.4 1.2 0.1 1.1 1.1 0.3 0.2 1.0 0.6 -0.2 0.8 1.6 0.5
Whole body fat mass 1.6 6.5 20.5 -3.8 1.2 -4.5 2.2 -3.2 3.0 1.6 -1.0 0.2 -0.4 -0.4 -3.7 1.9 0.5 -3.8
Leg fat mass (right) 1.3 4.9 15.4 -3.3 1.2 -3.9 2.2 -2.7 2.8 1.5 -0.8 0.4 -0.1 -0.3 -3.2 1.7 0.8 -3.1
Arm predicted mass (right) 1.0 5.1 12.9 -2.5 1.4 -3.6 2.9 -2.3 3.3 1.2 -0.3 -0.6 1.3 0.1 -3.3 1.1 3.0 -2.5
Pulse rate, automated reading 0.8 2.6 6.4 -2.2 -0.7 -1.8 2.2 -2.2 0.8 -0.4 -2.5 -1.3 -0.8 -1.7 -2.3 -0.6 0.5 -1.5
Alcohol intake frequency. 1.0 2.3 5.4 1.4 1.9 0.4 -1.3 1.7 0.5 1.7 2.3 2.0 1.4 2.0 1.5 1.7 -0.1 1.1
Comparative height size at age 10 1.6 8.6 23.7 -3.9 0.6 -4.5 3.0 -3.9 3.1 0.6 -2.6 -2.1 0.1 -1.2 -4.9 -0.3 2.3 -4.3
Number of full sisters 0.4 0.5 1.6 0.1 -0.8 0.5 -0.6 -0.0 -0.9 -0.4 -0.7 -0.7 -1.0 -0.7 0.4 -0.5 -1.3 0.3
Suffer from ‘nerves’ 0.8 1.2 2.7 -0.6 -1.6 0.3 -0.0 -0.8 -1.3 -1.4 -1.6 -1.0 -1.6 -1.4 -0.2 -1.1 -1.1 0.1
Overall health rating 1.6 3.4 8.1 -2.8 -1.2 -2.0 2.1 -2.7 0.4 -0.5 -2.2 -1.1 -2.0 -2.2 -2.3 -0.5 -1.1 -2.0
Chest pain or discomfort 0.3 0.4 0.9 0.5 -0.6 0.6 -0.7 0.5 -1.0 -0.9 0.5 0.3 -0.6 -0.2 0.8 -0.2 -0.9 0.2
Had major operations 1.8 2.1 5.4 -1.3 1.6 -2.0 2.0 -0.8 2.3 1.8 -0.7 0.8 1.1 0.8 -1.5 1.7 1.6 -0.2
Age at last live birth 0.5 0.7 2.0 0.8 0.5 0.6 0.0 0.9 0.2 0.9 1.2 1.0 0.3 0.8 1.1 1.3 -0.2 1.4
Family relationship satisfaction 0.9 1.2 3.7 1.1 0.2 1.3 -0.4 1.3 -0.5 0.7 1.6 1.1 0.3 0.7 1.7 1.0 -0.1 1.9
Leg pain on walking 2.4 3.0 5.5 -2.1 -1.6 -1.3 1.4 -2.3 -0.5 -1.9 -2.0 -2.2 -1.6 -2.1 -2.2 -1.4 0.1 -1.8
Qualifications: NVQ or HND or HNC or equivalent 1.3 1.5 4.5 -1.2 -0.7 -0.8 0.4 -1.4 -0.2 -1.2 -2.1 -1.9 -0.7 -1.0 -1.7 -1.2 0.3 -1.6
Commuting to job workplace: Car/motor vehicle 0.3 0.4 1.5 -0.7 -0.4 -0.5 0.7 -0.7 0.0 -0.6 -1.2 -0.4 -0.3 -0.8 -0.8 -0.7 0.4 -0.3
Illness, injury, bereavement, stress in last 2 years 3.9 4.7 8.1 -2.6 -1.6 -1.8 2.4 -2.8 -0.0 -1.9 -2.8 -2.3 -1.2 -2.5 -2.9 -2.3 0.3 -2.5
Medication: Aspirin 1.1 1.4 3.7 0.8 -1.5 1.7 -0.4 0.7 -1.9 -0.8 0.4 -0.0 -1.2 -0.6 1.6 -0.2 -1.3 1.9
Supplements: Vitamin C 0.5 0.6 3.6 0.5 -0.5 0.6 -1.9 0.3 -1.2 -1.0 -0.2 -0.4 -0.7 0.2 0.4 -0.6 -0.9 -0.5
Knee pain experienced in last month 1.4 2.1 4.6 -1.5 -1.3 -0.8 0.2 -1.7 -0.5 -1.5 -1.8 -2.1 -1.4 -1.6 -1.7 -1.4 -0.4 -2.1
Hypertension (Self-reported) 0.5 1.4 3.1 -0.7 -1.5 -0.1 -0.5 -1.0 -1.2 -1.7 -1.8 -1.3 -1.5 -1.4 -0.7 -1.5 -1.0 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 3.0 3.5 8.2 -0.3 -2.6 1.2 -1.1 -0.7 -2.4 -2.7 -1.3 -2.1 -2.3 -2.4 0.0 -2.9 -2.0 -0.8
Illnesses of father: Heart disease 1.2 1.6 5.4 1.7 -0.9 2.3 -1.3 1.4 -1.5 -0.6 0.6 -0.0 -0.3 0.1 1.8 -0.4 -0.3 2.3
Illnesses of siblings: Diabetes 0.3 0.4 1.2 -0.8 0.2 -1.1 0.4 -0.8 0.6 0.2 -0.7 -0.4 -0.1 -0.2 -0.9 0.4 0.0 -0.9
Smoking status: Previous 0.2 0.3 1.8 -0.5 0.1 -0.6 0.8 -0.2 0.5 0.7 -0.1 1.3 -0.2 -0.3 -0.0 0.3 -0.6 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.4 9.0 -2.1 1.6 -3.0 1.7 -1.7 3.0 1.8 -0.8 0.3 0.8 0.3 -2.6 1.2 1.5 -2.3
Whole body fat-free mass 0.9 5.3 14.9 -2.7 1.6 -3.9 2.1 -2.5 3.3 1.3 -0.3 -0.4 1.0 0.2 -3.5 1.0 2.2 -3.5
Leg fat-free mass (right) 1.1 5.6 16.7 -2.9 1.9 -4.1 1.9 -2.4 3.5 1.9 -0.1 0.3 0.8 0.4 -3.4 1.7 1.5 -3.6
Arm fat percentage (left) 0.7 2.7 8.5 -2.6 0.7 -2.9 0.8 -2.0 1.6 1.2 -0.4 0.7 -0.9 -0.3 -2.1 1.4 -1.0 -2.8
Average weekly red wine intake 2.2 3.2 8.5 -0.8 2.4 -2.4 1.5 -0.3 2.9 2.6 0.7 1.6 1.9 1.5 -1.1 2.4 1.7 -0.7
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.6 0.2 -0.4 0.6 0.2 0.1 -0.3 -0.4 0.1 -0.8 0.1 -0.3 0.0 -0.8 0.3 -0.1
Mood swings 0.7 1.3 3.7 -0.4 -1.5 0.6 -1.2 -0.6 -1.8 -1.5 -0.8 -0.6 -1.9 -1.2 0.2 -0.9 -1.6 -0.1
Loneliness, isolation 0.7 1.0 2.0 1.1 0.5 1.0 -0.9 1.2 -0.6 0.6 1.4 1.1 0.4 0.9 1.4 1.0 -0.1 1.4
Long-standing illness, disability or infirmity 0.5 0.8 2.0 0.6 -0.2 0.9 -1.0 0.8 -1.0 -0.1 0.4 1.2 -0.6 0.3 1.3 0.6 -1.4 1.1
Ever had bowel cancer screening 0.3 0.4 1.9 -0.1 -0.6 0.4 1.4 -0.3 -0.3 -0.6 0.0 -0.5 -0.0 -0.7 0.1 -0.1 0.7 1.2
Diabetes diagnosed by doctor 2.0 3.3 7.4 -2.7 -1.4 -1.8 2.2 -2.6 0.1 -0.9 -2.4 -1.3 -2.0 -2.2 -2.2 -0.3 -0.7 -1.5
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 4.1 0.3 2.0 -1.0 -0.9 0.6 1.5 1.6 1.4 1.6 1.5 1.7 -0.1 1.5 1.0 -0.5
Friendships satisfaction 1.6 2.0 5.7 2.1 -0.2 2.3 -0.2 2.0 -1.1 -0.2 1.4 0.7 0.8 0.5 2.3 -0.2 0.2 2.4
Qualifications: nursing, teaching 2.8 4.3 8.7 2.8 1.3 2.1 -2.3 3.0 -0.2 1.3 2.4 2.5 1.5 2.4 2.9 1.4 -0.0 2.1
Commuting to job workplace: Walk 0.4 0.4 1.8 0.7 0.0 0.7 -1.3 0.7 -0.6 -0.0 0.6 0.4 -0.2 0.6 0.9 0.4 -0.9 0.2
Eye problems/disorders: Cataract 2.6 3.1 6.1 -2.1 -1.5 -1.5 0.2 -2.4 -0.3 -1.7 -2.5 -1.6 -2.1 -2.0 -2.0 -1.1 -1.0 -2.1
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 5.4 -0.2 2.1 -1.4 1.3 -0.0 2.3 1.9 1.0 1.1 2.0 1.3 -0.6 1.6 1.8 0.2
Medication for cholesterol 0.4 0.6 1.5 0.6 0.8 0.4 -0.5 0.7 0.5 0.7 1.2 1.0 0.8 1.1 0.6 1.1 0.6 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.8 6.6 -0.3 -2.0 0.7 2.6 -0.6 -1.0 -1.1 -1.0 -1.1 -1.0 -2.0 0.2 -1.2 0.0 2.0
Back pain experienced in last month 0.4 0.6 3.0 -0.9 -0.5 -0.3 -0.7 -0.6 -0.7 -0.7 -0.5 0.6 -1.6 -0.4 -0.2 0.5 -1.7 -0.3
Mineral and other dietary supplements 0.5 0.7 2.1 0.7 0.7 0.4 -0.3 1.0 0.3 1.2 1.3 1.4 0.5 0.6 1.1 0.7 -0.7 0.6
Breast cancer (self-reported) 0.2 0.2 0.7 0.6 -0.1 0.7 0.1 0.4 -0.1 -0.1 0.7 -0.6 0.5 0.2 0.3 -0.2 0.8 0.3
Asthma (self-reported) 0.2 0.4 1.0 0.5 -0.8 0.9 -0.2 0.4 -1.0 -0.4 -0.2 -0.0 -0.6 -0.7 0.9 -0.8 -1.0 0.4
Osteoporosis (self-reported) 0.3 0.4 2.8 -0.2 -0.3 0.1 -0.7 -0.1 -0.4 0.1 -0.4 0.3 -1.0 -0.4 0.2 -0.0 -1.7 -0.6
Osteoarthritis (self-reported) 0.8 1.1 2.4 -0.6 -1.5 0.1 -0.5 -0.8 -1.0 -1.5 -1.0 -1.3 -1.2 -1.2 -0.8 -1.5 -0.5 -0.9
Medication: Aspirin 0.8 1.0 3.9 0.7 -1.2 1.4 0.1 0.6 -1.4 -0.3 0.6 0.3 -1.0 -0.4 1.5 0.3 -1.0 2.0
Medication: Gliclazide 0.7 0.8 1.4 -0.9 -1.2 -0.2 1.1 -1.0 -0.6 -1.2 -1.2 -0.9 -1.0 -1.0 -0.7 -0.1 0.3 0.6
Illnesses of father: None of the above (group 1) 2.4 2.9 7.6 -2.4 0.7 -2.8 2.4 -2.2 1.9 0.7 -0.9 -0.6 0.2 -0.6 -2.7 0.4 1.4 -2.1
Smoking status: Current 0.2 0.3 0.8 -0.4 0.7 -0.8 0.4 -0.2 0.9 0.4 -0.2 0.3 0.4 0.3 -0.5 0.7 0.4 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.5 0.4 0.2 0.4 -1.2 0.7 -0.7 -0.0 0.5 0.9 -0.2 0.3 0.8 0.2 -1.0 0.3
Whole body water mass 0.9 5.0 14.1 -2.6 1.6 -3.8 2.1 -2.4 3.2 1.3 -0.3 -0.4 1.0 0.2 -3.4 1.0 2.1 -3.4
Leg predicted mass (right) 1.1 5.7 17.0 -2.9 1.9 -4.1 1.9 -2.4 3.5 1.9 -0.1 0.3 0.8 0.4 -3.4 1.7 1.5 -3.7
Arm fat mass (left) 0.9 3.6 11.7 -2.8 1.0 -3.4 1.2 -2.3 2.1 1.2 -0.3 0.6 -0.5 -0.2 -2.6 1.4 -0.3 -3.2
Number of self-reported non-cancer illnesses 0.9 1.6 5.7 0.9 -1.3 1.8 -0.9 0.9 -1.9 -0.9 0.2 0.4 -1.2 -0.4 1.7 -0.1 -1.2 2.4
Average weekly champagne plus white wine intake 0.9 1.2 4.1 0.7 1.4 -0.2 -2.0 1.0 0.4 0.9 1.4 1.5 0.7 1.6 0.6 0.9 -0.6 -0.6
Miserableness 0.4 0.7 1.8 0.5 0.9 -0.1 -0.6 0.7 0.5 1.0 1.2 1.3 0.5 1.0 0.7 1.3 0.1 0.6
Guilty feelings 2.1 3.1 7.6 2.3 0.5 2.0 -2.4 2.4 -1.1 0.4 2.7 1.8 0.7 1.6 2.6 0.5 -0.8 1.5
Wears glasses or contact lenses 0.9 1.0 2.6 1.1 -0.0 1.2 -1.6 1.1 -0.9 -0.2 1.3 1.1 -0.4 0.6 1.6 0.4 -1.4 0.6
Ever taken oral contraceptive pill 0.7 0.8 3.2 -1.0 -0.2 -0.9 -0.2 -0.9 0.1 -0.3 -1.3 -0.4 -0.9 -0.9 -0.9 -0.8 -1.2 -1.8
Hearing aid user 0.2 0.3 1.8 -0.3 -0.4 -0.0 1.4 -0.2 0.3 -0.1 -0.5 -0.1 -0.1 -0.4 0.1 0.4 0.2 0.9
Mother’s age at death 2.2 2.8 5.3 2.2 1.6 1.4 -1.1 2.3 0.7 1.5 2.3 1.6 2.0 2.2 2.0 1.1 0.6 1.4
Financial situation satisfaction 1.0 1.3 3.3 -0.6 -1.8 0.8 0.7 -0.6 -1.5 -1.1 -0.9 -0.8 -1.6 -1.7 0.2 -1.2 -1.3 0.7
Tinnitus: Yes, now most or all of the time 2.5 2.9 6.2 1.6 1.6 0.9 -0.0 2.0 0.7 1.7 2.5 2.4 1.5 1.6 1.9 1.8 0.3 2.5
Commuting to job workplace: Public transport 2.1 2.5 5.6 2.1 0.7 1.7 -1.9 2.3 -0.5 0.7 1.9 1.6 0.9 1.7 2.4 0.9 -0.4 1.9
Eye problems/disorders: Glaucoma 0.4 0.5 1.2 -0.5 -0.7 -0.3 1.1 -0.7 0.1 -0.5 -0.6 -0.9 -0.2 -1.0 -0.6 -1.0 0.3 -0.5
Medication: Blood pressure 0.8 1.6 3.4 -1.6 -1.2 -1.2 1.1 -1.6 -0.2 -0.7 -1.9 -0.8 -1.4 -1.7 -1.3 -1.0 -0.8 -1.1
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.8 0.2 0.3 0.3 -1.1 0.5 -0.4 0.6 0.3 0.7 -0.5 0.3 0.7 0.6 -1.7 -0.4
Supplements: Fish oil (including cod liver oil) 0.9 1.1 3.2 -0.6 -1.3 0.0 0.0 -1.0 -0.9 -1.8 -1.4 -1.6 -0.9 -1.1 -0.9 -1.3 0.2 -0.5
High cholesterol (Self-reported) 0.8 1.4 4.4 -0.0 -1.7 1.0 -1.0 -0.1 -1.9 -1.2 -1.0 -0.5 -1.8 -1.1 0.6 -1.0 -2.1 0.1
Medication: Bendroflumethiazide 1.2 1.8 4.1 -1.0 -1.9 -0.1 0.0 -1.1 -1.3 -1.4 -2.0 -1.0 -1.9 -1.8 -0.7 -1.5 -1.4 -0.7
Medication: Paracetamol 1.6 2.5 6.3 -1.6 -1.6 -0.8 -0.4 -1.7 -1.0 -1.6 -2.5 -1.0 -2.3 -1.7 -1.3 -1.3 -1.8 -1.5
Medication: Lisinopril 0.7 0.9 2.0 1.2 0.8 0.6 -1.1 1.3 0.0 0.4 1.2 1.3 0.9 1.4 1.0 0.7 0.5 0.9
Medication: Atorvastatin 0.4 0.5 1.8 0.3 0.4 0.1 0.8 0.5 0.3 1.0 0.2 1.0 0.5 0.7 0.7 1.3 0.3 1.2
Illnesses of father: High blood pressure 1.1 1.4 3.5 -1.5 -0.6 -1.3 0.4 -1.6 0.3 -0.6 -1.5 -1.2 -1.0 -1.1 -1.6 -0.7 -0.7 -1.9
Alcohol drinker status: Never 0.6 0.7 2.2 -0.3 1.1 -0.9 0.9 0.1 1.0 1.4 0.1 1.1 0.6 0.7 -0.1 1.5 0.3 0.6
Ever smoked 1.4 2.5 6.1 2.1 -0.3 2.1 -2.5 2.1 -1.7 -0.6 1.3 1.4 -0.1 0.7 2.4 -0.5 -1.7 1.4
Basal metabolic rate 1.2 6.4 18.7 -3.2 1.6 -4.3 2.3 -2.9 3.5 1.4 -0.6 -0.3 0.8 -0.0 -3.9 1.2 1.9 -3.9
Leg fat percentage (left) 0.5 1.7 5.1 -2.1 0.5 -2.3 1.7 -1.7 1.4 0.8 -0.5 0.3 -0.4 -0.5 -1.7 1.3 0.3 -1.2
Arm fat-free mass (left) 1.0 4.8 13.4 -2.5 1.5 -3.7 2.4 -2.4 3.2 1.3 -0.3 -0.4 1.1 0.2 -3.3 1.1 2.4 -2.9
Number of operations (self-reported) 1.4 2.1 6.0 0.0 2.0 -1.0 0.3 0.5 1.8 2.5 1.5 1.9 1.3 1.6 0.1 2.2 0.8 0.4
Average weekly beer plus cider intake 0.5 0.8 2.3 -1.1 0.4 -1.3 -0.6 -0.7 0.5 0.5 -0.8 0.8 -0.7 -0.0 -0.7 0.6 -1.5 -1.5
Irritability 0.3 0.5 2.6 0.2 0.4 0.1 -1.6 0.4 -0.4 0.3 0.7 1.1 -0.3 0.6 0.5 0.3 -1.4 -0.6
Risk taking 0.1 0.1 0.8 -0.1 0.2 -0.0 -0.9 -0.0 0.1 0.2 -0.4 0.1 -0.2 0.1 -0.0 0.2 -0.4 -0.9
Ever had prostate specific antigen (PSA) test 1.1 1.2 3.3 1.3 0.7 0.9 -0.7 1.2 0.1 0.4 1.6 0.8 1.2 1.2 1.1 0.8 1.3 1.8
Fractured/broken bones in last 5 years 0.4 0.5 1.2 0.8 0.4 0.5 -1.0 0.9 -0.3 0.5 1.1 0.5 0.1 0.6 1.0 0.5 -0.8 0.1
Age started oral contraceptive pill 1.2 1.5 3.9 1.1 -1.5 1.9 -0.5 0.8 -2.0 -1.5 0.3 -0.5 -0.8 -0.9 1.4 -1.4 -1.2 1.2
Diastolic blood pressure, automated reading 1.5 4.6 13.4 -2.9 1.1 -3.7 2.1 -2.6 2.9 1.5 -1.2 -0.4 0.1 -0.4 -3.3 0.9 1.1 -2.9
Ever depressed for a whole week 0.1 0.1 0.3 -0.1 -0.5 0.2 0.3 -0.1 -0.2 0.0 0.6 0.0 -0.4 -0.3 0.2 0.0 -0.2 0.3
Unable to work because of sickness or disability 0.4 0.5 3.8 -0.3 -0.2 -0.1 1.9 -0.3 0.5 0.1 -0.1 -0.1 0.4 -0.5 -0.3 0.1 1.3 1.1
Commuting to job workplace: Cycle 0.2 0.3 0.7 -0.0 0.6 -0.3 -0.1 0.2 0.5 0.8 0.9 0.8 0.2 0.5 0.1 0.7 -0.4 -0.2
Myopia 1.3 1.9 4.4 -0.2 -2.1 1.1 -0.5 -0.5 -2.1 -2.0 -0.3 -1.6 -2.0 -1.6 0.2 -1.6 -1.7 -0.2
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.7 0.1 0.5 -0.1 0.7 0.1 0.8 0.5 0.7 0.0 0.8 0.2 -0.1 0.0 0.8 -0.0
Cholesterol lowering medication 1.5 2.2 4.6 -1.6 -1.4 -0.9 1.4 -1.7 -0.7 -1.5 -2.1 -1.7 -1.4 -2.1 -1.6 -1.7 -0.6 -1.1
Medication: Omeprazole (e.g. Zanprol) 4.3 5.2 9.5 -1.0 -2.8 0.5 -1.5 -1.5 -2.4 -2.8 -2.1 -2.8 -2.9 -2.4 -0.9 -3.1 -2.6 -2.7
Pain experienced in last month 0.3 0.5 1.4 0.7 -0.9 1.2 0.6 0.4 -0.7 -0.6 -0.1 -1.0 0.0 -0.6 0.6 -1.2 0.2 0.5
Supplements: Calcium 0.1 0.1 0.2 -0.5 0.2 -0.5 0.1 -0.4 0.0 -0.3 -0.3 0.4 -0.2 -0.0 -0.4 0.4 -0.1 -0.3
Basal cell carcinoma (self-reported) 0.5 0.5 1.9 -0.8 0.7 -1.1 1.1 -0.5 1.4 0.7 -0.3 0.1 0.6 -0.1 -0.8 0.4 0.8 -0.2
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.3 0.0 0.0 0.4 -0.6 0.3 -0.5 0.3 0.3 0.9 -0.6 0.3 0.6 0.8 -1.2 0.2
Deep venous thrombosis (DVT) (self-reported) 2.6 3.4 10.3 1.5 1.8 0.2 1.4 1.5 1.5 1.4 2.0 0.8 2.8 2.0 0.9 1.9 3.2 2.4
Heart disease (siblings) 1.8 2.2 6.5 1.2 -1.6 1.9 -1.6 0.8 -2.5 -2.2 0.0 -1.3 -0.8 -0.9 1.1 -2.1 -0.6 0.8
Alcohol drinker status: Previous 0.4 0.5 1.3 1.1 0.4 0.7 -1.1 1.0 -0.2 0.0 0.9 0.8 0.6 0.7 0.9 -0.2 -0.0 0.6
Pack years of smoking 1.0 1.4 3.6 1.4 -0.7 1.9 -1.8 1.3 -1.8 -0.8 0.4 0.1 -0.5 0.1 1.7 -0.8 -1.4 0.9
Impedance of whole body 0.5 2.5 6.1 -2.4 -0.9 -1.7 1.1 -2.3 0.2 -0.3 -2.5 -1.0 -1.9 -1.6 -2.0 -0.1 -1.2 -1.6
Leg fat mass (left) 1.2 4.6 14.3 -3.1 1.2 -3.8 2.3 -2.6 2.7 1.4 -0.8 0.3 -0.1 -0.3 -3.1 1.7 0.9 -2.9
Arm predicted mass (left) 1.1 5.5 14.8 -2.6 1.6 -3.9 2.6 -2.5 3.4 1.3 -0.3 -0.5 1.2 0.2 -3.5 1.2 2.8 -2.9