Hub : Genes

ATP5C1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2040 0.0370 4.5e-12 0.185 0.135 0.183 0.192 0.196 5.5e-22 4.5e-16 9.1e-22 7e-23 2.4e-23
2 GTEx Adipose Subcutaneous 0.1110 0.0460 4.9e-03 0.014 NA 0.018 NA 0.019 2.5e-02 NA 1.3e-02 NA 1.0e-02
3 GTEx Adipose Visceral Omentum 0.1890 0.0760 9.5e-03 -0.005 NA -0.005 NA -0.004 8.3e-01 NA 9.5e-01 NA 6.1e-01
4 GTEx Artery Tibial 0.1123 0.0474 7.2e-03 -0.002 NA -0.002 NA -0.001 5.4e-01 NA 4.6e-01 NA 4.3e-01
5 GTEx Lung 0.1143 0.0446 4.4e-03 0.026 NA 0.021 NA 0.033 4.2e-03 NA 9.5e-03 NA 1.5e-03
6 GTEx Muscle Skeletal 0.2098 0.0455 2.2e-08 0.132 NA 0.101 NA 0.114 7.4e-13 NA 3.8e-10 NA 3.2e-11
7 GTEx Whole Blood 0.0850 0.0320 4.5e-03 -0.003 NA 0.009 NA 0.005 9.7e-01 NA 4.2e-02 NA 1.0e-01
8 TCGA Prostate Adenocarcinoma 0.0224 0.0134 4.1e-03 0.011 0.021 0.022 NA 0.017 2.3e-02 2.6e-03 1.8e-03 NA 5.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.3 3.8 -0.3 -1.7 -1.0 0.2 -2.0 0.1 -1.2 -0.9
Bipolar Disorder or Schizophrenia 0.3 0.6 1.9 -0.8 -1.3 -0.7 0.4 -1.4 -0.1 -0.4 0.1
Depressed Affect (Nagel 2018) 0.7 1.6 4.0 -0.6 0.9 1.2 1.9 1.4 0.4 2.0 -0.0
Depression (Nagel 2018) 0.4 0.6 2.5 -0.5 0.4 0.7 0.7 0.8 0.1 1.6 -0.3
Intelligence (Savage-Jansen 2018) 0.4 1.3 5.5 -0.7 0.9 1.2 -0.1 -0.3 -2.4 0.3 1.4
Neuroticism (Nagel 2018) 0.4 1.0 2.6 -0.4 0.7 0.5 1.6 1.6 0.3 1.3 0.1
Schizophrenia (2018) 0.2 0.3 1.0 -0.8 -0.3 -0.1 0.4 -0.2 -0.3 1.0 0.9
Schizophrenia vs Biploar Disorder 0.4 0.5 1.7 0.5 0.8 0.9 -0.1 1.3 0.1 0.7 -0.2
Worry (Nagel 2018) 0.6 1.2 2.1 -1.3 1.0 1.4 1.4 0.0 -1.1 0.9 1.1
Alzheimer’s Disease (in mother) 0.6 0.7 1.9 1.4 0.1 1.0 1.0 1.2 0.4 0.0 -0.4
Alzheimer’s Disease (in father) 2.0 2.1 7.0 -0.9 1.9 0.9 -0.5 -0.5 -2.7 1.4 1.5
Alzheimer’s Disease (including proxy) 0.9 1.3 2.4 0.4 1.3 1.5 1.0 1.0 -1.1 1.3 0.8
Crohns Disease (2017) 0.5 1.2 4.9 -0.9 -0.9 0.0 -2.2 -0.6 1.1 -0.9 -0.5
Irritable Bowel Disease (IBD) 0.6 1.4 5.7 -2.4 -0.5 -0.1 -1.7 -1.5 0.1 0.0 0.6
Ulcerative Colitis (UC) 1.2 2.2 7.7 -2.8 -0.1 -0.3 -1.3 -2.1 -1.1 0.7 1.4
Major Depression (MDD) 1.0 1.2 4.1 0.9 -1.2 -2.0 1.2 0.2 0.9 0.2 -0.8
Reaction Time 0.1 0.3 0.8 -0.5 0.9 0.8 -0.3 0.4 0.3 -0.3 0.3
Verbal and Numeric Reasoning (VNR) 0.8 1.8 5.7 -0.6 1.4 0.5 1.3 -0.2 -2.4 -0.3 2.1
Breast Cancer 0.3 0.7 2.4 0.6 -0.2 0.2 -0.8 -1.3 -1.5 -0.8 -0.1
Ovarian Cancer 0.9 1.2 3.3 1.1 -1.0 -0.1 -1.4 0.0 1.3 -0.9 -1.8
Prostate Cancer 1.3 1.8 3.6 -1.4 1.7 1.4 -0.1 -0.2 -1.9 0.5 1.9
Age at First Birth 0.5 0.7 2.4 -0.2 0.8 1.0 0.2 0.3 -1.2 -0.4 1.6
Bipolar Disorder (2011) 1.9 1.8 5.5 -0.3 -2.1 -1.7 -0.6 -2.3 -0.2 -1.0 -0.1
Body Mass Index (BMI) (2010) 1.8 2.4 3.9 2.0 -1.7 -1.2 -2.0 -0.1 1.6 -1.1 -1.9
Coronary Artery Disease (CAD) 0.5 0.6 1.3 -0.5 0.8 1.1 -1.1 0.9 0.6 0.4 0.2
Crohns Disease (2012) 0.3 0.5 1.3 -1.1 -0.7 0.5 -0.7 -0.7 0.3 -0.3 -0.9
Mean Putamen Volume 0.8 0.9 4.5 -0.1 -0.0 -0.0 -2.1 -0.8 -0.8 -0.1 1.0
Fasting Glucose 1.5 1.8 3.8 1.2 -1.9 -1.2 0.1 -0.1 1.3 1.6 -1.8
HbA1C 0.6 0.7 1.4 0.2 -1.2 0.0 0.4 1.1 1.1 -1.0 -0.7
HDL Cholesterol 0.4 0.7 1.9 -0.3 1.4 0.4 1.2 0.4 -1.1 -0.1 0.8
LDL Cholesterol 0.5 0.8 2.0 0.8 -0.9 -0.7 -0.5 -0.1 1.4 0.6 -1.4
Lupus 0.2 0.3 0.9 -0.8 -0.5 0.3 0.6 -0.9 0.4 0.0 0.4
Neuroticism (2016) 0.5 0.7 2.4 0.7 -1.1 -0.7 -0.7 -0.4 0.5 0.6 -1.5
Primary Biliary Cirrhosis 0.7 0.9 2.8 -0.0 -0.9 -1.2 -1.7 -1.0 -0.2 -1.2 0.1
Rheumatoid Arthritis 1.3 1.8 4.6 -2.1 1.1 2.1 0.1 -0.4 -0.7 1.5 0.9
Schizophrenia (2014) 0.1 0.2 0.7 -0.4 -0.5 0.3 0.5 0.3 0.8 0.2 0.1
Triglycerides 0.2 0.3 1.1 -0.1 0.3 -0.3 1.0 0.6 0.6 0.5 0.0
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.8 0.5 1.1 1.3 1.0 0.3 0.2 1.2 -0.0
Ulcerative Colitis 1.4 2.0 11.6 -3.4 0.2 0.2 0.3 -1.1 -0.4 1.2 1.3
Blood Eosinophil Count 0.3 2.3 8.6 -2.0 0.9 1.8 0.5 -0.6 -0.5 2.9 1.0
Blood Platelet Count 0.1 1.4 4.5 1.3 -0.7 0.4 -0.3 0.9 2.1 -0.6 -1.7
Blood Red Count 1.0 9.2 28.5 -1.6 2.3 2.6 -1.5 -4.9 -5.3 1.2 1.6
Blood White Count 0.2 1.5 3.8 -0.9 0.1 1.4 -1.3 -1.9 -0.9 1.7 0.0
Heel T-Score 0.0 0.2 0.6 0.8 0.3 -0.1 -0.3 -0.7 0.0 0.3 -0.5
BMI 0.0 0.3 0.8 -0.9 -0.3 0.1 -0.7 -0.2 -0.8 -0.3 0.3
Height 0.2 3.1 10.0 1.1 -3.2 -1.2 -2.0 -0.4 1.4 0.1 -2.5
Waist Hip Ratio (WHR) 0.2 0.8 3.0 -0.8 -0.3 1.0 0.5 -1.7 -1.2 0.1 0.2
Systolic Blood Pressure 0.1 0.6 3.0 -0.2 0.8 1.7 -0.0 0.2 1.1 -0.0 -0.4
Smoking Status 1.3 3.1 9.6 1.6 -2.2 -0.8 0.8 0.5 3.1 -0.5 -2.5
Allergy or Eczema 0.2 0.5 1.1 0.2 -0.5 -0.5 0.8 1.0 0.8 1.0 -0.5
Cardiovascular Disease 0.2 0.6 2.6 -0.7 0.8 0.5 -0.2 0.2 -0.4 1.6 0.4
Hypothyroidism (self reported) 0.3 0.6 2.0 -0.7 1.4 1.1 0.5 0.5 -0.4 0.7 0.4
Respiratory disease 1.1 2.4 7.0 1.3 -0.8 -1.1 -2.6 -0.3 1.4 0.0 -2.6
Type 2 Diabetes (T2D) (2018) 1.0 2.0 9.6 0.9 -0.4 -0.4 -3.1 -1.3 -1.0 -1.0 -1.1
Lung FEV1/FVC ratio 0.5 2.4 5.9 -1.9 1.1 1.5 0.7 2.4 -0.8 -0.5 2.3
Lung FVC 0.2 1.2 3.9 0.6 -0.6 -0.7 0.2 1.7 1.2 -2.0 0.1
Neuroticism 0.3 0.6 1.3 0.7 -0.6 -1.1 0.9 0.4 0.7 0.5 -1.1
Chronotype (morning person) 0.5 1.1 2.2 0.4 0.3 1.4 -1.5 -1.4 -1.4 -0.5 -0.2
Hair Pigment 0.1 2.7 8.6 2.1 -1.7 -0.9 -1.1 0.4 1.0 -2.9 -1.6
Tanning 0.0 0.3 1.0 -0.5 -0.4 -1.0 0.0 0.1 -0.6 0.3 0.3
Hand grip strength (left) 0.8 2.2 4.7 1.1 -2.2 -1.6 -1.6 -1.8 0.2 -0.0 -1.8
Number of treatments/medications taken 0.1 0.2 0.5 -0.2 -0.7 0.1 0.1 -0.4 0.2 0.5 -0.6
Average weekly spirits intake 0.9 1.1 5.9 -0.0 -0.5 -0.5 2.4 -0.7 -1.1 -0.6 0.4
Sensitivity / hurt feelings 1.0 1.7 4.6 1.6 -1.6 -0.9 -0.2 1.0 1.5 -0.1 -2.1
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.7 -1.1 0.3 -0.1 1.0 -0.6 -1.0 1.3 0.2
Hearing difficulty/problems: Yes 2.5 3.8 8.7 3.0 -1.3 -2.2 -1.9 0.9 1.4 -0.5 -2.9
Relative age of first facial hair 0.6 1.1 2.3 1.3 -0.5 1.0 -1.5 -1.0 -0.3 -1.5 -0.8
Other serious medical condition/disability diagnosed by doctor 2.0 2.6 5.0 -1.4 1.6 1.8 0.2 -2.2 -2.2 1.6 0.8
Ever used hormone-replacement therapy (HRT) 0.7 0.8 4.0 -0.2 0.9 0.7 -0.8 0.4 -0.5 2.0 0.5
Ever had hysterectomy (womb removed) 0.8 0.9 4.2 0.2 -0.0 -0.5 -1.0 0.2 2.0 0.6 -1.3
Systolic blood pressure, automated reading 0.5 1.3 4.6 -0.6 1.3 2.1 -0.1 1.4 1.3 0.5 0.2
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 2.1 -1.4 0.2 0.2 -0.5 -0.7 -0.6 1.0 -0.1
Angina 0.4 0.5 1.4 -0.5 -0.6 -1.0 0.1 1.2 0.9 -0.1 -0.0
Medication for hormone replacement therapy 0.6 0.7 1.8 -0.2 -0.2 -0.6 0.2 1.0 1.3 1.3 -0.6
Vitamin and mineral supplements 0.9 1.2 2.9 0.4 0.1 -1.7 -1.5 -0.9 -0.5 1.5 0.8
Supplements: Zinc 0.8 0.8 4.1 0.1 0.3 -0.1 -0.2 2.0 0.9 1.1 -0.7
Medication: Co-codamol 0.7 0.8 1.8 -1.1 -1.4 -1.0 -0.2 -0.9 -0.3 -1.0 -0.4
Medication: Metformin 0.8 1.1 3.8 0.6 -1.9 -0.9 -0.3 -0.9 -0.2 -1.3 -1.0
Diabetes (father) 0.4 0.4 2.4 0.1 0.5 0.5 0.2 0.5 -0.1 1.6 -0.6
Diabetes (mother) 0.4 0.5 2.0 0.1 -0.5 -0.6 0.8 -0.8 -0.5 -1.4 -0.5
Severe depression (siblings) 0.2 0.2 1.1 -0.2 0.5 -0.7 0.1 -0.2 -1.1 -0.2 0.1
Pack years adult smoking proportion 2.4 3.7 10.5 1.8 -2.5 -1.6 -0.7 -1.6 1.9 -0.3 -3.2
Impedance of leg (right) 0.3 1.2 2.7 1.6 -0.8 0.2 1.6 -1.4 -0.2 -1.2 -0.9
Leg fat-free mass (left) 0.1 0.8 3.9 -0.7 -1.0 -0.2 -2.0 0.4 0.2 0.4 -0.6
Trunk fat percentage 0.2 0.6 2.1 -0.9 0.6 1.5 0.0 0.8 -0.7 -0.1 0.7
Hand grip strength (right) 0.8 2.3 7.8 0.3 -2.1 -0.5 -1.5 -2.8 -0.5 1.3 -1.3
Townsend deprivation index at recruitment 0.3 0.5 1.1 0.8 -0.7 0.6 -0.4 -0.8 0.6 0.0 -1.1
Current tobacco smoking 0.9 1.4 5.5 1.3 -0.9 -0.7 -0.5 -0.4 1.4 0.7 -2.3
Average weekly fortified wine intake 1.5 1.8 4.6 -0.7 2.1 1.9 0.3 1.5 -0.4 0.8 1.5
Maternal smoking around birth 0.5 0.8 2.0 -1.0 1.4 1.4 0.3 0.9 -0.1 0.5 0.3
Fed-up feelings 0.3 0.6 2.6 -0.1 0.2 0.3 1.6 0.1 -0.5 1.2 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 3.2 0.4 -1.8 -1.1 -0.5 -0.2 1.1 0.3 -1.6
Relative age voice broke 0.3 0.5 1.7 0.8 0.6 0.6 1.3 0.4 -0.8 0.3 -0.3
Taking other prescription medications 0.3 0.5 1.2 -0.4 -0.6 -1.1 0.7 -0.8 -0.5 -0.8 -0.7
Age when periods started (menarche) 0.2 0.4 2.5 -0.4 0.3 -0.2 0.3 -1.6 -0.1 -0.3 -0.3
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 3.6 -1.0 0.8 1.9 -0.4 0.8 1.1 1.1 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 0.7 0.6 0.2 -0.2 0.3 0.8 0.6 -0.9 -0.5
Tinnitus: Yes, but not now, but have in the past 0.4 0.5 1.6 -0.1 -0.5 -1.3 0.9 -0.5 -0.3 -0.3 -0.8
Qualifications: CSEs or equivalent 0.5 0.6 2.0 -1.0 -1.4 -0.2 0.5 -0.3 1.0 -0.0 -0.7
Serious illness, injury or assault to yourself 0.7 0.9 2.1 0.8 -1.0 0.0 -0.7 -0.5 1.0 -1.3 -1.4
High blood pressure 0.8 2.1 6.1 -1.9 1.4 2.5 -0.5 0.8 -0.7 1.6 1.0
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.6 0.5 0.1 -0.6 0.6 1.3 0.5 1.6 -0.4
Multivitamins +/- minerals 0.6 0.7 2.6 -0.3 0.3 1.3 1.6 0.4 0.4 -0.9 -0.4
Stomach or abdominal pain in last month 0.9 1.1 5.2 0.5 -0.4 -2.3 -0.3 1.4 0.6 0.6 0.2
Supplements: Glucosamine 0.5 0.7 2.2 0.7 -0.1 -0.9 -1.5 -0.2 -0.1 -0.9 -0.9
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 3.5 0.7 -1.9 -1.2 -0.4 -0.1 1.3 0.2 -1.8
Medication: Atenolol 0.8 1.1 3.2 -0.8 0.6 -1.2 0.2 -0.5 -1.8 0.8 1.4
Medication: Levothyroxine sodium 0.3 0.5 2.8 -0.9 0.7 1.7 -0.3 0.3 0.3 0.1 0.0
Sitting height 0.2 1.4 3.8 0.8 -1.4 -0.6 -2.0 -1.0 -0.1 1.1 -1.5
Chronic bronchitis/emphysema (father) 0.0 0.1 0.3 -0.2 -0.0 0.1 0.2 0.0 -0.1 0.3 -0.5
High blood pressure (mother) 0.5 0.7 2.4 0.3 -1.6 -0.9 -0.0 -0.9 -0.3 -1.2 -0.6
Body mass index (BMI) 0.2 0.6 3.0 -1.7 0.4 0.5 0.0 1.0 -0.6 0.1 0.6
Impedance of leg (left) 0.2 1.2 2.5 1.6 -1.2 -0.2 0.9 -1.3 0.2 -1.3 -1.0
Leg predicted mass (left) 0.2 0.8 4.2 -0.7 -1.0 -0.2 -2.1 0.3 0.1 0.4 -0.6
Trunk fat mass 0.1 0.3 0.9 -0.8 0.1 1.0 -0.5 0.7 -0.5 -0.1 0.2
Waist circumference 0.1 0.5 2.1 -1.4 0.1 1.0 -0.2 0.2 -0.7 0.0 0.2
Number of incorrect matches in round 1.2 2.0 4.7 0.5 -2.1 -1.9 -0.6 -0.1 1.4 -2.2 -1.0
Past tobacco smoking 0.8 1.5 3.6 -0.1 1.9 1.5 -0.7 -1.0 -1.7 0.9 1.2
Alcohol usually taken with meals 0.8 1.2 6.2 1.1 0.7 -0.7 -2.5 0.2 -0.5 -1.1 -0.3
Nervous feelings 0.4 0.7 1.5 -0.7 0.6 1.2 1.2 0.4 -1.0 -0.5 0.4
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 2.3 -1.1 -0.3 0.3 1.3 0.1 -0.2 1.5 0.1
Hearing difficulty/problems with background noise 0.8 1.3 4.1 1.2 -1.5 -0.2 -2.0 0.5 0.0 0.1 -1.6
Hair/balding pattern: Pattern 2 0.3 0.4 1.5 0.7 -0.3 -0.5 0.5 -0.5 -1.2 0.4 0.3
Had menopause 0.2 0.3 1.0 -0.2 0.5 1.0 0.5 0.4 -0.3 0.5 -0.2
Had other major operations 0.9 1.1 3.5 0.1 -0.1 -0.1 -1.2 1.7 1.9 0.0 -0.9
Forced vital capacity (FVC) 0.8 3.1 7.5 1.8 -2.7 -1.8 -1.4 0.1 1.9 -1.2 -2.0
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 3.0 1.7 -0.5 -0.6 -0.5 -0.1 0.4 -0.9 -1.6
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.8 0.6 0.2 -0.5 0.5 -1.3 -0.8 -0.7 0.3
Qualifications: None of the above 0.8 1.8 6.3 -2.5 1.0 1.6 0.1 -0.2 -0.6 1.2 1.6
Financial difficulties in last 2 years 1.1 1.5 2.5 1.3 -1.6 -1.2 -1.1 -1.1 0.7 1.0 -1.4
Mouth/teeth dental problems 1.2 1.8 8.5 2.9 0.1 -0.5 -1.4 -1.2 -0.3 0.7 -1.2
Heart attack 0.6 0.7 3.9 1.0 -0.2 -2.0 0.3 0.1 -0.2 0.2 -0.9
Allergy 0.4 1.0 5.4 -0.3 0.1 -0.5 0.1 -0.6 -0.9 -2.3 1.0
Pain all over the body in last month 0.4 0.5 1.4 -0.9 0.3 0.7 -1.2 0.2 0.9 0.1 -0.3
Diabetes (self-reported) 0.4 0.7 2.4 -0.2 1.2 0.7 -0.7 0.0 -1.5 -0.6 0.4
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 3.5 -0.0 0.2 0.2 0.2 -0.3 -0.7 1.9 0.3
Medication: Ramipril 0.7 1.0 4.0 0.5 0.0 0.1 -2.0 0.3 0.9 -1.3 -0.9
Medication: Simvastatin 0.1 0.2 0.6 0.1 -0.4 0.1 0.1 -0.6 0.5 -0.1 -0.8
Fluid intelligence score 0.4 0.8 2.6 0.3 1.3 1.6 -0.2 0.8 -0.9 -0.4 0.9
Illnesses of siblings 0.4 0.6 2.6 -0.1 -1.1 -1.6 0.1 -0.2 0.9 -0.0 0.3
Neuroticism score 0.2 0.4 0.9 0.1 0.0 0.1 0.8 0.9 0.4 0.6 -0.9
Weight 0.1 0.3 0.9 -1.0 -0.4 0.3 -0.9 0.7 -0.2 -0.0 -0.3
Impedance of arm (right) 0.2 1.0 2.7 1.3 0.6 1.0 1.6 -0.1 -0.2 -1.3 0.8
Arm fat percentage (right) 0.3 1.3 2.0 -1.4 1.1 1.4 0.8 1.3 -0.9 -0.4 1.2
Trunk fat-free mass 0.3 1.6 3.6 0.6 -1.7 -1.4 -1.9 0.3 0.8 0.3 -1.8
Hip circumference 0.1 0.4 1.3 -0.8 -0.0 0.5 -1.1 0.9 0.2 0.6 -0.5
Time employed in main current job 1.6 1.9 3.5 -1.5 1.9 1.8 0.9 0.3 -1.4 -0.5 1.7
Alcohol intake versus 10 years previously 0.9 1.4 3.1 0.5 -1.6 -1.8 -0.7 -1.4 -0.3 -0.5 -1.5
Father’s age at death 0.4 0.6 1.6 0.5 1.2 0.4 -1.3 0.1 -1.0 0.3 0.0
Worrier / anxious feelings 0.3 0.5 1.3 -0.6 1.0 1.1 0.3 0.7 -0.4 -0.9 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.1 -0.7 -1.1 -0.1 -0.5 -0.1 0.3 0.5 -0.5
Falls in the last year 1.6 2.2 5.7 1.1 -1.7 -1.2 -1.6 -0.3 1.0 -1.6 -2.4
Hair/balding pattern: Pattern 3 0.4 0.7 1.9 -0.8 -0.9 0.2 -1.4 -1.2 0.4 -0.4 -0.4
Number of live births 0.6 0.8 3.5 0.3 0.1 0.7 0.5 -1.1 -0.9 1.9 -0.2
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 3.4 0.6 -1.8 -0.9 -1.2 0.4 1.1 -1.3 -0.8
Pulse rate 2.1 3.6 11.7 -1.9 0.5 0.5 0.9 -2.6 -3.4 0.7 2.3
Happiness 0.6 0.8 3.4 -0.6 -0.0 0.1 1.0 -0.9 -1.8 0.5 0.7
Noisy workplace 0.2 0.3 0.7 0.6 -0.8 -0.8 0.1 0.1 0.2 0.5 -0.5
Qualifications: A levels/AS levels or equivalent 0.7 1.6 4.6 1.0 -0.3 -0.8 -2.2 -1.2 -1.0 -2.0 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.9 3.6 0.4 -0.8 -0.2 0.8 -0.8 0.1 1.9 -1.1
Mouth/teeth dental problems: Dentures 0.8 1.4 5.8 -2.4 1.1 1.1 1.0 -0.2 -0.7 0.7 1.0
Asthma 0.4 0.7 1.8 -0.0 -0.3 0.2 -1.0 -0.2 1.2 1.2 -1.3
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 5.3 1.0 -2.3 -1.0 -0.7 -0.0 1.8 0.1 -2.0
Medication: Cholesterol lowering 0.1 0.2 0.9 1.0 -0.1 -0.5 -0.2 -0.2 -0.3 -0.3 -0.1
Depression (self-reported) 0.2 0.3 1.5 -1.2 -0.4 -0.3 -0.3 -0.6 0.0 0.4 -0.2
Medication: Lansoprazole 0.3 0.4 1.4 0.6 0.4 -1.2 0.8 0.3 0.1 0.5 -0.3
Prospective memory result 1.3 1.6 3.9 -1.4 1.8 1.8 -0.5 2.0 0.1 -0.3 0.5
Lung cancer (father) 1.3 1.5 4.6 -2.2 1.0 1.2 -0.1 1.6 0.4 -0.1 1.5
Illnesses of mother 0.9 1.1 3.2 -1.8 0.5 1.0 0.0 -0.2 -0.3 0.9 1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.1 3.3 1.8 -1.6 -1.3 -1.5 1.1 1.4 -1.6 -1.3
Pulse wave Arterial Stiffness index 2.1 2.5 6.3 -2.2 0.5 1.6 1.6 -1.0 -1.4 2.5 0.4
Impedance of arm (left) 0.2 1.0 2.9 1.2 0.9 1.0 1.7 -0.3 -0.7 -0.5 1.0
Arm fat mass (right) 0.1 0.4 1.2 -1.1 0.2 0.6 -0.2 0.9 -0.7 -0.3 0.5
Trunk predicted mass 0.3 1.5 3.5 0.6 -1.6 -1.3 -1.9 0.4 0.8 0.3 -1.8
Standing height 0.2 2.2 4.9 1.7 -2.1 -0.6 -2.2 -0.3 0.9 -0.4 -2.0
Length of working week for main job 0.8 0.9 2.7 0.9 -1.0 0.6 -1.6 -0.4 -0.1 -1.0 -0.9
Exposure to tobacco smoke at home 5.5 6.2 15.4 -2.9 2.2 2.1 3.9 0.8 -0.4 3.6 1.7
Breastfed as a baby 0.9 1.1 4.1 1.9 0.1 -0.3 0.7 -0.7 -2.0 -0.1 0.4
Tense / ‘highly strung’ 0.2 0.3 1.6 -1.3 -0.6 -0.3 -0.1 0.5 0.2 0.3 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 1.6 0.8 0.9 0.1 1.0 1.3 0.2 -0.1 -0.9
Hair/balding pattern: Pattern 4 0.2 0.5 2.0 -0.3 0.2 0.6 0.6 0.6 0.8 -1.4 -0.2
Birth weight of first child 0.4 0.7 2.1 0.5 -0.5 -1.3 0.4 1.4 0.9 -0.7 -0.4
Peak expiratory flow (PEF) 0.5 1.2 4.5 0.4 -2.1 -1.3 -0.6 0.8 1.3 -0.1 -1.0
Pulse wave reflection index 0.8 1.0 3.6 -0.4 -0.1 1.1 0.9 0.5 1.2 1.9 -0.7
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.9 -0.8 -0.5 -0.3 0.3 0.1 0.0 0.9 -0.2
Loud music exposure frequency 1.1 1.2 3.4 1.2 -1.1 -1.8 0.2 -0.8 0.1 0.3 -1.8
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.4 1.2 -0.0 -0.5 -0.6 -0.3 0.1 -0.1 -0.6
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 5.5 -1.5 0.2 0.2 2.3 1.2 -0.1 -0.7 1.4
Blood clot in the leg (DVT) 0.8 1.1 5.3 1.0 -0.6 0.2 -0.3 0.7 2.3 0.0 -1.2
Medication: Paracetamol 0.9 1.4 4.0 0.8 -1.9 -2.0 0.1 -0.1 0.6 -1.2 -1.1
Headache pain in last month 2.8 4.8 8.4 1.9 -2.9 -2.9 -1.3 -0.5 2.4 -2.3 -2.3
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.6 -0.1 -0.6 0.1 -0.1 -0.7 0.4 -0.7 -0.5
Glaucoma (self-reported) 0.8 1.0 2.6 -0.5 1.5 0.6 1.6 0.4 -0.8 -0.2 1.3
Gout (self-reported) 1.7 2.3 7.1 -1.6 1.0 0.9 1.5 -1.1 -2.7 0.8 1.7
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 3.3 -0.6 1.8 0.7 0.7 0.8 -0.5 1.3 0.6
Medication: Amlodipine 0.8 1.2 5.5 0.1 0.1 0.2 0.9 -0.1 -1.7 2.3 0.3
Medication: Ventolin 100micrograms inhaler 0.9 1.1 2.8 -0.7 -0.2 0.8 -1.7 0.8 1.6 1.2 -0.6
Birth weight 0.2 0.4 1.2 0.2 0.2 -0.4 -0.2 1.1 0.2 -1.0 -0.7
Chronic bronchitis/emphysema (mother) 0.4 0.4 1.3 0.9 -0.6 -1.1 0.4 -0.3 -0.2 -0.3 -0.8
High blood pressure (siblings) 1.0 1.4 4.8 0.6 2.2 2.1 -0.4 1.0 -0.3 0.3 0.1
Forced vital capacity (FVC), Best measure 0.9 3.3 6.8 2.6 -2.0 -1.6 -1.7 0.7 1.9 -1.4 -2.0
Body fat percentage 0.2 0.9 2.0 -1.3 0.8 1.4 0.6 0.8 -1.1 -0.2 0.9
Leg fat percentage (right) 0.2 0.8 2.0 -1.4 0.4 1.2 1.0 0.5 -1.0 0.3 0.4
Arm fat-free mass (right) 0.2 1.3 3.9 -0.2 -1.4 -0.6 -2.0 0.3 0.5 0.9 -1.6
Exposure to tobacco smoke outside home 0.5 0.7 2.3 0.3 -1.5 -1.4 0.2 -0.4 0.5 0.1 -0.8
Comparative body size at age 10 0.3 0.9 2.1 -1.1 1.5 1.2 -0.5 0.7 -0.7 -0.2 1.0
Number of full brothers 1.2 1.6 3.4 1.3 -1.2 -1.5 -0.2 1.2 1.8 -0.4 -1.4
Worry too long after embarrassment 0.8 1.4 5.2 1.1 -0.4 -1.0 -0.5 2.3 1.4 -0.5 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 1.3 0.7 0.9 -0.5 -0.5 1.1 0.5 0.7 -0.7
Wheeze or whistling in the chest in last year 0.5 1.0 1.9 1.2 -0.9 0.3 -0.8 -1.2 0.6 0.9 -1.4
Number of children fathered 0.7 0.7 2.0 -1.4 0.5 1.3 0.1 0.7 0.9 0.7 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 3.4 0.2 0.3 0.6 -1.8 0.6 0.8 0.5 -0.2
Age at first live birth 0.2 0.4 1.4 0.9 -0.4 -0.4 -1.2 -0.0 0.6 -0.8 0.1
Pulse wave peak to peak time 2.1 2.5 6.0 2.2 -0.4 -1.4 -1.7 1.1 1.5 -2.5 -0.5
Health satisfaction 1.8 2.4 7.2 -1.9 -0.5 -0.0 0.3 -1.9 -2.7 0.8 1.9
Shortness of breath walking on level ground 0.2 0.3 0.6 -0.3 -0.6 -0.7 0.1 -0.5 -0.6 -0.8 0.2
Qualifications: College or University degree 0.6 2.0 4.7 1.3 2.0 1.2 -2.2 1.7 -0.2 -1.0 0.5
Eye problems/disorders: None of the above 0.6 0.7 1.6 -0.3 1.2 -0.8 -0.2 0.9 -1.3 -0.0 1.0
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.8 -1.2 -1.3 -1.0 1.7 -0.2 -0.1 0.6 -0.1
Emphysema/chronic bronchitis 0.2 0.2 1.2 -0.1 -0.3 0.0 -1.1 -0.0 0.3 0.6 -0.2
Medication for pain relief, constipation, heartburn 0.7 1.1 3.0 -0.4 1.7 1.5 0.0 -0.2 -0.6 1.3 1.1
Neck or shoulder pain in last month 0.4 0.5 1.5 -0.2 -1.2 -0.7 1.0 0.4 -0.2 -0.5 -0.8
Medication: Blood pressure 0.1 0.2 0.6 0.1 0.4 -0.0 -0.8 0.6 -0.3 0.7 0.0
Angina (self-reported) 0.3 0.3 1.4 -0.5 -0.3 -0.6 0.2 1.2 0.7 0.3 0.1
Migraine (self-reported) 0.5 0.6 1.4 -0.1 1.2 0.3 0.9 -0.2 -1.1 -0.0 1.0
Medication: Ibuprofen 1.6 1.9 5.1 0.9 -1.9 -0.5 -0.8 0.4 2.2 0.4 -2.3
Medication: Allopurinol 2.6 3.4 9.1 -1.9 1.0 1.6 1.4 -2.2 -3.0 0.5 1.9
Medication: Omeprazole 2.2 2.7 7.9 1.4 -2.8 -1.9 -0.4 -0.9 0.0 -1.6 -2.0
Medication: Seretide 50 evohaler 0.1 0.1 0.4 0.3 -0.1 0.3 -0.5 0.6 0.6 -0.1 -0.0
Mean time to correctly identify matches 0.5 1.0 2.6 0.1 1.6 1.5 -0.4 1.6 0.6 -0.3 0.2
Heart disease (mother) 1.2 1.5 4.1 1.2 -0.9 -0.7 -1.9 -1.1 -0.1 0.1 -2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 2.7 0.1 -1.6 -0.8 -1.2 -1.5 0.3 0.6 -1.2
Whole body fat mass 0.1 0.4 1.0 -1.0 -0.0 0.8 -0.5 0.6 -0.8 -0.1 0.3
Leg fat mass (right) 0.1 0.3 1.4 -1.2 -0.4 0.8 -0.0 0.3 -0.7 -0.0 -0.1
Arm predicted mass (right) 0.2 1.2 3.8 -0.1 -1.5 -0.6 -2.0 0.1 0.6 0.5 -1.6
Pulse rate, automated reading 1.2 3.8 10.6 -2.1 -0.3 -0.2 0.9 -2.8 -3.3 0.7 2.3
Alcohol intake frequency. 0.8 1.9 5.8 -2.4 1.2 1.5 0.3 -1.4 -1.5 -0.0 1.3
Comparative height size at age 10 0.3 1.8 3.7 0.7 -1.9 -0.6 -1.9 0.3 1.5 -1.1 -1.8
Number of full sisters 1.1 1.4 4.3 0.4 -0.1 -1.1 1.3 -1.4 -2.1 1.1 0.5
Suffer from ‘nerves’ 0.6 1.0 2.4 -1.6 0.9 1.0 1.2 -0.3 -1.1 0.8 0.7
Overall health rating 0.5 1.1 2.5 -1.4 -0.7 -0.1 0.8 -1.6 -0.9 1.4 0.4
Chest pain or discomfort 0.1 0.1 0.5 -0.7 0.3 -0.3 0.3 0.0 0.1 0.1 0.4
Had major operations 1.1 1.3 3.2 0.4 1.3 1.4 -0.4 1.8 1.3 0.9 -0.7
Age at last live birth 0.5 0.7 3.1 1.0 -0.8 -0.3 -1.8 -0.7 -0.2 -0.1 -0.2
Family relationship satisfaction 0.6 0.7 3.8 -0.7 0.3 0.4 -0.3 -0.2 -0.9 2.0 0.4
Leg pain on walking 0.1 0.1 0.6 -0.1 0.0 -0.5 0.8 0.1 -0.4 -0.3 -0.0
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.6 -0.9 -1.2 -0.8 -0.7 -0.4 0.4 -0.5 0.0
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.6 -0.9 -1.3 -0.4 0.5 -1.2 0.3 -0.1 -0.8
Illness, injury, bereavement, stress in last 2 years 1.9 2.3 7.0 -1.7 2.2 0.6 0.0 0.4 -1.7 0.2 2.6
Medication: Aspirin 0.4 0.5 1.8 -0.6 0.5 1.3 -0.1 -0.4 -1.0 -0.3 0.6
Supplements: Vitamin C 1.6 1.9 7.5 0.7 -0.4 -0.0 -0.4 1.6 1.3 -2.7 -1.5
Knee pain experienced in last month 0.6 1.0 2.5 0.5 -0.8 -0.6 0.4 1.5 0.9 1.6 -0.8
Hypertension (Self-reported) 1.0 2.7 5.2 -2.0 2.0 2.3 -0.1 0.9 -1.2 1.8 1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.9 0.1 -0.1 0.3 -0.3 0.5 0.1 0.4 -0.9
Illnesses of father: Heart disease 1.4 2.0 6.0 -0.9 1.2 2.5 1.5 -1.2 -1.1 1.1 1.2
Illnesses of siblings: Diabetes 0.3 0.4 1.8 -0.3 -1.4 -0.9 -0.0 0.4 -0.1 -0.4 -0.3
Smoking status: Previous 0.4 0.5 1.9 -0.5 -0.9 -0.6 1.4 0.8 0.5 -0.3 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.5 1.6 0.3 -0.8 -0.9 -1.3 -1.0 0.1 0.6 -0.2
Whole body fat-free mass 0.2 1.4 4.6 0.1 -1.6 -0.9 -2.1 0.4 0.7 0.4 -1.5
Leg fat-free mass (right) 0.2 1.1 5.9 -0.6 -1.2 -0.4 -2.4 0.3 0.5 0.3 -0.7
Arm fat percentage (left) 0.3 1.0 2.0 -1.4 0.9 1.2 0.7 1.0 -1.0 0.1 1.2
Average weekly red wine intake 0.8 1.1 5.7 0.2 2.4 1.0 0.3 0.6 -1.0 -0.0 1.0
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.9 0.3 1.4 0.2 1.2 -0.6 -0.3 -0.1 0.3
Mood swings 0.9 1.7 4.2 0.1 -0.6 -0.4 2.0 1.5 1.1 2.0 -1.0
Loneliness, isolation 0.2 0.3 0.8 0.2 0.6 -0.0 -0.4 -0.3 -0.9 0.9 -0.4
Long-standing illness, disability or infirmity 0.7 1.0 6.0 -0.7 -0.1 0.2 0.2 -2.5 -1.1 -0.0 -0.3
Ever had bowel cancer screening 0.9 1.1 2.9 0.2 -0.7 -0.4 -1.2 0.6 1.7 -0.5 -1.7
Diabetes diagnosed by doctor 0.3 0.4 1.3 0.1 0.0 -0.1 -0.9 -0.4 -1.0 -1.1 -0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.0 2.8 0.3 -1.7 -0.8 -1.0 -1.6 -1.0 0.4 -0.2
Friendships satisfaction 1.5 1.8 6.1 -1.2 1.2 0.7 -0.7 -0.3 -1.8 2.5 1.2
Qualifications: nursing, teaching 0.4 0.7 2.0 1.4 -0.6 -1.1 -1.3 0.4 0.2 -0.4 0.3
Commuting to job workplace: Walk 0.5 0.6 1.7 -0.1 0.9 0.1 -1.3 0.6 -0.7 0.8 0.6
Eye problems/disorders: Cataract 0.8 1.0 2.2 1.1 -1.3 -0.8 0.6 -0.2 1.2 0.3 -1.5
Mouth/teeth dental problems: Mouth ulcers 0.5 0.9 3.3 0.1 0.0 0.7 -0.2 1.8 1.5 -0.4 -0.7
Medication for cholesterol 0.6 0.9 2.6 1.0 0.0 -0.6 -0.8 -1.3 -1.6 -1.1 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.1 -0.3 0.9 -0.4 1.1 0.7 -0.3 -0.1 -0.2
Back pain experienced in last month 1.1 1.7 5.7 1.4 -1.2 -2.4 -0.1 1.1 0.6 -1.1 -1.4
Mineral and other dietary supplements 0.2 0.3 0.7 -0.1 -0.1 -0.8 -0.6 -0.8 -0.0 0.3 0.8
Breast cancer (self-reported) 0.6 0.7 1.8 -0.9 -0.1 1.3 0.5 0.1 1.2 1.1 -0.4
Asthma (self-reported) 0.4 0.8 2.4 0.3 -0.3 0.0 -1.4 0.0 1.3 0.8 -1.5
Osteoporosis (self-reported) 0.5 0.6 1.8 1.3 -0.1 -0.4 0.2 -0.7 -0.0 -1.1 -0.9
Osteoarthritis (self-reported) 0.7 1.0 2.1 -0.4 -1.2 0.1 0.7 0.6 1.4 -1.0 -1.5
Medication: Aspirin 0.6 0.8 2.6 -0.8 0.3 1.2 0.1 -1.0 -1.6 0.2 0.9
Medication: Gliclazide 2.4 2.8 8.2 1.1 -2.9 -1.3 -1.0 -2.3 0.1 -1.4 -1.6
Illnesses of father: None of the above (group 1) 2.9 3.6 7.1 0.5 -2.7 -2.7 -1.9 -0.2 2.2 -2.1 -1.1
Smoking status: Current 1.5 2.3 7.5 1.8 -1.3 -1.2 -0.9 -0.0 2.0 0.2 -2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.2 4.8 0.8 -0.6 -0.1 -0.7 1.3 1.1 -2.2 -0.8
Whole body water mass 0.2 1.2 4.7 -0.0 -1.4 -0.8 -2.2 0.4 0.5 0.3 -1.4
Leg predicted mass (right) 0.2 1.0 5.6 -0.7 -1.1 -0.4 -2.4 0.3 0.4 0.4 -0.7
Arm fat mass (left) 0.1 0.4 1.4 -1.2 0.3 0.6 -0.2 0.8 -0.8 0.0 0.5
Number of self-reported non-cancer illnesses 0.4 0.6 2.5 0.3 1.0 -0.2 -0.2 -0.6 -1.6 0.9 -0.6
Average weekly champagne plus white wine intake 0.3 0.3 0.9 -0.5 0.2 0.9 0.7 -0.3 -0.5 0.8 0.4
Miserableness 0.3 0.4 1.6 0.7 -0.5 -0.6 -0.1 0.7 0.5 0.3 -1.3
Guilty feelings 0.3 0.5 0.9 0.5 -0.6 -0.7 0.8 0.5 0.8 0.6 -1.0
Wears glasses or contact lenses 0.8 0.9 1.7 -1.0 0.2 1.0 1.2 0.9 1.3 1.0 -0.4
Ever taken oral contraceptive pill 0.7 0.7 2.0 0.4 -1.2 -1.4 -0.3 0.8 0.9 -0.8 -0.4
Hearing aid user 0.9 1.0 4.0 -0.0 1.3 1.1 0.5 2.0 0.1 0.7 0.4
Mother’s age at death 1.6 2.0 6.0 0.5 -2.4 -2.5 -1.4 -1.3 -0.2 -0.3 -0.7
Financial situation satisfaction 0.8 1.0 4.4 -0.2 -2.1 -1.4 -0.3 -0.5 -0.8 -0.4 -0.7
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.4 -0.3 0.3 0.2 -0.5 0.6 0.1 0.1 0.3
Commuting to job workplace: Public transport 1.1 1.4 5.2 -0.5 1.0 2.3 -1.0 0.5 -0.6 0.4 1.6
Eye problems/disorders: Glaucoma 0.7 0.8 2.0 -0.9 0.9 1.3 1.4 -0.3 -0.2 -0.1 1.0
Medication: Blood pressure 0.1 0.3 1.1 0.0 0.6 0.5 0.1 1.0 0.6 0.0 -0.2
Pain type(s) experienced in last month: Hip pain 3.0 3.8 9.8 1.7 -3.1 -3.1 -1.4 -0.8 0.6 0.1 -2.1
Supplements: Fish oil (including cod liver oil) 0.3 0.4 2.0 -0.1 -0.4 0.5 1.4 0.4 -0.2 0.4 -0.2
High cholesterol (Self-reported) 0.3 0.5 1.5 -0.0 0.2 -0.4 1.2 -0.5 -0.8 1.0 -0.2
Medication: Bendroflumethiazide 0.5 0.8 2.4 1.2 -0.4 0.5 -1.6 0.5 0.3 -0.1 -1.3
Medication: Paracetamol 0.5 0.7 2.1 0.8 -1.4 -1.3 0.3 0.3 0.3 -0.6 -0.8
Medication: Lisinopril 0.8 1.0 3.5 -1.9 0.5 0.6 0.0 1.2 -0.2 0.5 1.5
Medication: Atorvastatin 0.2 0.3 0.8 0.7 0.3 -0.3 0.2 -0.3 -0.7 0.9 0.1
Illnesses of father: High blood pressure 1.2 1.4 2.9 -0.8 1.6 1.7 0.5 1.4 -1.2 0.6 1.1
Alcohol drinker status: Never 0.5 0.6 3.3 0.5 0.8 0.2 0.8 -0.1 0.2 -1.8 0.3
Ever smoked 1.1 1.9 5.4 0.6 -2.3 -1.8 0.3 0.6 1.5 -0.8 -1.7
Basal metabolic rate 0.2 1.0 3.9 -0.2 -1.4 -0.7 -2.0 0.4 0.4 0.3 -1.2
Leg fat percentage (left) 0.1 0.5 2.1 -1.4 0.3 0.8 0.5 0.5 -0.8 0.3 0.4
Arm fat-free mass (left) 0.2 1.0 2.7 -0.2 -1.2 -0.7 -1.6 0.7 0.7 0.2 -1.4
Number of operations (self-reported) 0.4 0.6 2.9 -0.0 0.8 0.0 -0.7 1.7 0.8 0.5 -0.4
Average weekly beer plus cider intake 0.3 0.4 1.6 -0.5 -0.8 0.2 -0.8 -0.4 1.3 0.2 -0.3
Irritability 0.3 0.6 1.9 -1.4 -0.6 -1.2 0.3 0.7 -0.2 0.6 0.1
Risk taking 2.3 3.3 7.3 1.0 -2.7 -1.9 -1.8 -2.4 -0.1 1.4 -1.8
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.7 -0.2 0.3 -0.4 -1.0 1.6 1.2 -0.9 -0.9
Fractured/broken bones in last 5 years 2.9 3.7 7.4 1.8 -2.7 -1.5 -1.4 -1.8 1.5 -1.8 -2.5
Age started oral contraceptive pill 0.9 1.1 5.2 2.3 -0.3 -0.9 0.6 0.4 -0.2 0.0 -1.4
Diastolic blood pressure, automated reading 0.4 1.3 3.0 -1.5 0.6 1.7 0.7 0.1 -0.6 1.2 1.4
Ever depressed for a whole week 0.2 0.3 1.3 1.2 0.4 -0.1 0.1 0.5 0.1 -0.1 -0.6
Unable to work because of sickness or disability 1.0 1.3 6.4 -0.9 -0.2 0.4 -1.3 -2.5 -0.9 0.4 -0.5
Commuting to job workplace: Cycle 0.5 0.6 3.1 0.5 -0.2 -0.4 -0.2 1.2 0.4 -1.8 0.0
Myopia 0.5 0.7 1.7 0.4 0.5 0.6 -1.3 1.3 0.3 -1.0 -0.5
Vascular/heart problems diagnosed by doctor 0.5 1.3 2.1 1.3 -1.3 -1.4 0.1 -1.5 0.0 -1.5 -0.7
Cholesterol lowering medication 0.4 0.6 1.7 -0.6 0.8 0.7 1.3 -0.5 -0.7 1.0 0.3
Medication: Omeprazole (e.g. Zanprol) 1.9 2.4 4.3 1.2 -2.1 -1.9 -0.3 -1.3 -0.7 -2.1 -1.8
Pain experienced in last month 1.3 2.1 6.9 -0.7 1.5 2.6 -0.6 -1.1 -1.7 -0.5 1.6
Supplements: Calcium 0.4 0.4 2.2 0.3 -0.5 -0.1 1.5 -0.4 0.2 -0.5 -0.6
Basal cell carcinoma (self-reported) 2.4 2.8 5.7 -1.8 2.4 2.3 1.5 0.5 -0.5 0.8 2.3
Heart attack/myocardial infarction (self-reported) 0.6 0.7 4.1 0.8 -0.3 -2.0 0.3 0.1 -0.2 0.4 -0.9
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 5.0 1.0 -0.4 0.2 -0.2 1.0 2.2 -0.2 -0.9
Heart disease (siblings) 0.4 0.5 1.4 -0.7 0.1 0.5 0.8 -0.8 -1.2 -0.5 -0.2
Alcohol drinker status: Previous 1.5 1.7 4.0 -1.2 1.5 2.0 0.5 -0.9 -1.6 1.2 1.1
Pack years of smoking 2.3 3.3 10.2 1.7 -2.3 -1.5 -0.6 -1.3 1.9 -0.5 -3.2
Impedance of whole body 0.2 1.0 3.2 1.3 0.1 0.8 1.8 -0.9 -0.4 -1.0 0.2
Leg fat mass (left) 0.1 0.3 1.4 -1.2 -0.4 0.7 -0.2 0.3 -0.7 0.1 -0.1
Arm predicted mass (left) 0.2 0.9 2.6 -0.2 -1.1 -0.5 -1.6 0.5 0.6 0.3 -1.4