TWAS hub - ATP5G3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.5340	0.0490	0.0e+00	0.221	0.293	0.296	0.365	0.263	2.1e-26	4.9e-36	2.0e-36	1.6e-46	6.2e-32
2	GTEx	Adrenal Gland	0.1681	0.0778	5.4e-03	0.159	NA	0.072	NA	0.135	2.5e-06	NA	1.4e-03	NA	1.4e-05
3	GTEx	Artery Aorta	0.1520	0.0530	8.3e-06	0.113	NA	0.067	NA	0.105	8.5e-07	NA	1.4e-04	NA	2.2e-06
4	GTEx	Artery Coronary	0.3960	0.1610	3.5e-03	0.073	NA	0.014	NA	0.029	1.9e-03	NA	1.1e-01	NA	3.6e-02
5	GTEx	Artery Tibial	0.2445	0.0470	0.0e+00	0.290	NA	0.264	NA	0.293	5.1e-23	NA	9.6e-21	NA	3.4e-23
6	GTEx	Brain Cerebellum	0.2350	0.0770	1.0e-04	0.177	NA	0.175	NA	0.201	6.6e-06	NA	7.3e-06	NA	1.3e-06
7	GTEx	Cells Transformed fibroblasts	0.0710	0.0320	3.0e-03	0.037	NA	-0.002	NA	0.011	8.6e-04	NA	5.2e-01	NA	4.6e-02
8	GTEx	Colon Transverse	0.1210	0.0470	4.1e-04	0.072	NA	0.036	NA	0.051	2.5e-04	NA	7.9e-03	NA	1.9e-03
9	GTEx	Esophagus Gastroesophageal Junction	0.1110	0.0520	6.9e-03	0.051	NA	0.074	NA	0.061	6.1e-03	NA	1.2e-03	NA	3.1e-03
10	GTEx	Esophagus Mucosa	0.1110	0.0410	1.7e-04	0.031	NA	0.063	NA	0.051	3.6e-03	NA	4.8e-05	NA	2.5e-04
11	GTEx	Esophagus Muscularis	0.1740	0.0500	7.7e-09	0.210	NA	0.197	NA	0.205	7.0e-13	NA	4.4e-12	NA	1.4e-12
12	GTEx	Lung	0.0733	0.0299	2.4e-04	0.069	NA	0.033	NA	0.040	6.0e-06	NA	1.4e-03	NA	5.0e-04
13	GTEx	Muscle Skeletal	0.0818	0.0273	4.3e-06	0.078	NA	0.072	NA	0.080	4.7e-08	NA	1.5e-07	NA	2.6e-08
14	GTEx	Nerve Tibial	0.0809	0.0322	5.1e-05	0.073	NA	0.082	NA	0.069	7.0e-06	NA	2.1e-06	NA	1.3e-05
15	GTEx	Skin Sun Exposed Lower leg	0.1050	0.0390	6.2e-05	0.065	NA	0.023	NA	0.040	4.8e-06	NA	4.8e-03	NA	2.7e-04
16	GTEx	Testis	0.3110	0.0770	7.4e-11	0.273	NA	0.225	NA	0.245	1.6e-12	NA	2.5e-10	NA	3.0e-11
17	GTEx	Thyroid	0.1370	0.0430	2.2e-07	0.128	NA	0.123	NA	0.133	5.4e-10	NA	1.2e-09	NA	2.3e-10
18	NTR	Blood	0.0207	0.0082	4.3e-04	0.024	0.010	0.019	0.016	0.021	2.7e-08	3.0e-04	8.0e-07	4.1e-06	1.5e-07
19	ROSMAP	Brain Pre-frontal Cortex	0.0881	0.0299	9.9e-10	0.087	0.091	0.107	0.089	0.087	3.0e-11	9.5e-12	1.3e-13	1.7e-11	2.5e-11
20	TCGA	Kidney Renal Clear Cell Carcinoma	0.0314	0.0190	4.1e-04	0.038	0.027	0.019	NA	0.024	3.7e-05	4.6e-04	2.6e-03	NA	9.1e-04
21	TCGA	Brain Lower Grade Glioma	0.0373	0.0244	1.4e-03	-0.002	0.008	0.007	NA	0.004	6.4e-01	4.1e-02	4.5e-02	NA	1.1e-01
22	TCGA	Prostate Adenocarcinoma	0.0503	0.0268	7.5e-06	0.025	0.034	0.028	NA	0.021	1.0e-03	1.6e-04	5.8e-04	NA	2.6e-03
23	TCGA	Thyroid Carcinoma	0.0550	0.0260	1.7e-06	0.041	0.060	0.062	NA	0.053	7.1e-05	1.7e-06	1.1e-06	NA	6.2e-06
24	TCGA	Uterine Corpus Endometrial Carcinoma	0.2160	0.1280	7.3e-04	0.087	0.067	0.035	NA	0.052	2.0e-03	6.1e-03	3.7e-02	NA	1.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Happiness	12.0	14.5	19.5	1.3	-3.7	-4.1	-4.1	-3.8	-4.3	-4.1	-4.1	-2.4	-3.9	-3.6	-3.9	-3.8	-4.0	-4.1	-3.9	-4.1	-3.9	-3.9	-4.2	-4.4	-3.1	-3.8	-3.4
Medication: Blood pressure	5.5	10.5	15.5	-2.0	2.8	3.1	3.7	3.4	3.9	3.7	3.5	1.7	3.3	3.0	3.2	3.0	3.2	3.5	3.1	3.6	3.6	3.5	3.5	3.4	2.9	3.1	2.9
Bipolar Disorder (2011)	5.4	5.2	8.9	-0.4	-2.7	-2.2	-1.0	-2.4	-2.2	-2.1	-2.1	-1.7	-2.1	-2.6	-2.7	-2.5	-1.9	-2.3	-2.5	-2.3	-2.1	-3.0	-2.2	-2.8	-2.1	-2.3	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	5.4	7.1	13.0	3.0	-2.2	-3.1	-2.8	-3.1	-2.7	-2.7	-3.0	-1.6	-3.0	-2.5	-2.3	-2.6	-1.4	-2.4	-2.6	-3.1	-3.6	-1.9	-3.0	-2.6	-2.4	-2.9	-2.4
Intelligence (Savage-Jansen 2018)	4.9	14.9	17.9	1.0	-4.0	-4.0	-3.6	-4.1	-3.9	-3.9	-4.2	-3.5	-4.1	-4.1	-4.0	-4.2	-3.6	-4.0	-4.1	-4.2	-3.8	-3.8	-3.8	-3.8	-4.2	-3.5	-4.1
Average weekly spirits intake	4.9	6.1	11.5	0.7	2.7	2.6	2.4	2.4	2.2	2.8	2.3	2.3	2.3	2.6	2.7	2.6	3.4	2.5	2.7	2.4	2.1	2.3	2.7	2.1	2.9	2.3	2.5
Health satisfaction	4.8	6.2	9.8	1.4	-2.3	-2.4	-2.4	-2.5	-2.9	-3.1	-3.0	-2.2	-2.7	-2.5	-2.6	-2.5	-1.9	-3.1	-2.5	-2.7	-2.5	-1.7	-2.8	-2.9	-2.0	-2.6	-2.0
Medication for cholesterol	4.7	7.1	10.6	1.1	-2.4	-2.4	-3.3	-2.7	-3.1	-2.8	-2.7	-1.0	-3.0	-2.6	-2.7	-2.6	-2.2	-2.9	-2.6	-2.8	-2.8	-2.9	-3.2	-3.1	-2.1	-3.0	-2.4
Medication: Lansoprazole	4.5	5.1	7.7	0.7	2.6	2.0	2.3	2.0	2.4	2.2	2.2	1.6	2.3	2.5	2.7	2.5	2.4	2.8	2.5	2.1	1.8	2.2	2.7	1.9	2.6	2.3	2.2
Mean time to correctly identify matches	4.4	8.4	12.0	-0.9	3.1	3.5	1.6	3.1	3.1	2.9	3.0	2.6	2.6	3.1	3.0	3.1	3.5	2.6	3.3	3.1	2.7	3.4	2.6	3.1	2.9	2.4	3.0
Impedance of arm (left)	4.1	19.2	27.9	0.7	-4.8	-4.0	-3.0	-4.4	-5.0	-5.2	-4.8	-5.2	-4.3	-4.5	-4.9	-4.6	-4.4	-5.3	-4.7	-4.8	-3.9	-3.5	-4.4	-4.4	-4.7	-3.1	-4.1
Neck or shoulder pain in last month	4.1	5.8	9.1	0.8	2.9	1.9	1.1	2.5	2.0	1.8	2.1	2.0	3.0	3.0	2.7	2.9	2.2	2.2	2.9	2.3	2.1	2.8	2.5	2.4	2.6	2.8	2.8
Reaction Time	4.0	7.6	11.0	-0.8	2.9	3.0	1.4	2.9	2.9	3.0	2.8	2.7	2.2	2.9	2.9	2.9	3.2	2.6	3.1	2.9	2.5	3.3	2.4	3.0	2.8	2.4	3.0
Medication: Ventolin 100micrograms inhaler	4.0	5.2	8.7	-0.6	2.3	2.3	0.8	2.6	2.6	2.4	2.8	2.3	2.4	2.4	2.3	2.4	2.9	2.0	2.5	2.6	2.2	1.8	1.5	2.4	2.6	1.4	2.8
Medication: Bendroflumethiazide	3.8	5.8	9.0	-2.5	1.9	2.3	2.5	2.6	3.0	3.0	3.0	0.8	2.3	1.8	2.3	2.0	2.4	2.6	2.2	2.8	2.9	2.3	2.4	2.6	2.2	2.2	2.3
Sensitivity / hurt feelings	3.7	6.4	8.7	0.2	2.9	2.3	1.8	2.5	2.6	2.5	2.7	2.1	2.5	2.9	2.9	2.8	2.0	2.9	2.8	2.6	2.3	2.5	3.0	2.8	2.5	2.6	2.6
Pulse wave reflection index	3.7	4.6	7.4	-2.4	1.8	2.4	1.2	2.4	2.5	2.7	2.7	2.1	2.2	1.8	1.9	1.9	2.0	2.2	2.0	2.6	2.5	1.6	2.2	2.1	2.0	1.5	1.7
Impedance of whole body	3.7	19.0	28.8	0.7	-4.9	-4.0	-2.9	-4.5	-4.8	-5.1	-4.8	-5.4	-4.3	-4.5	-4.9	-4.6	-4.7	-5.1	-4.7	-4.8	-3.8	-3.6	-4.2	-4.5	-4.6	-2.8	-4.0
Bipolar Disorder (2018)	3.6	5.7	7.3	0.4	-2.7	-2.7	-1.1	-2.6	-2.6	-2.2	-2.6	-1.7	-1.9	-2.7	-2.6	-2.7	-2.2	-2.5	-2.7	-2.6	-2.4	-2.3	-2.5	-2.5	-2.6	-2.3	-2.5
Medication: Atenolol	3.5	4.3	8.4	-0.6	2.2	1.9	2.1	2.0	2.5	2.9	2.4	2.0	1.7	2.0	2.4	2.0	1.3	2.6	2.2	2.3	1.8	1.6	2.4	2.2	2.0	2.0	1.8
Impedance of arm (right)	3.5	16.5	30.2	0.2	-4.6	-3.6	-2.5	-4.1	-4.5	-5.0	-4.4	-5.5	-3.8	-4.3	-4.6	-4.4	-4.2	-4.8	-4.4	-4.5	-3.3	-2.8	-3.9	-4.0	-4.6	-2.5	-3.9
Mouth/teeth dental problems: Mouth ulcers	3.5	5.6	9.8	0.0	-2.5	-2.4	-2.1	-2.3	-2.6	-2.2	-2.5	-1.6	-2.3	-2.4	-2.6	-2.5	-2.4	-2.7	-2.5	-2.4	-2.3	-3.1	-2.5	-2.6	-2.2	-2.3	-2.5
Birth weight of first child	3.2	5.9	11.0	-0.4	-2.9	-2.7	-0.6	-2.4	-2.5	-2.6	-2.7	-2.9	-1.5	-2.5	-2.8	-2.5	-3.3	-2.5	-2.7	-2.5	-1.7	-2.6	-2.0	-2.5	-2.7	-1.6	-2.7
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	6.3	0.8	2.1	2.5	0.7	2.0	1.7	1.4	1.6	1.5	1.5	2.2	1.9	2.1	2.4	1.4	2.1	1.9	1.5	1.9	1.3	1.8	2.2	1.2	2.3
Maternal smoking around birth	3.0	4.3	8.2	1.5	2.4	1.7	2.0	1.8	2.0	1.9	1.8	1.9	2.5	2.3	2.5	2.3	1.3	2.7	2.2	1.9	1.8	2.0	2.9	2.2	1.6	2.1	1.5
Smoking Status	2.8	6.8	11.3	0.9	3.4	2.2	0.2	2.8	2.4	2.4	2.3	3.1	1.8	3.1	3.2	3.1	2.9	2.6	3.0	2.7	2.2	3.0	2.5	2.8	2.8	1.8	2.9
Qualifications: College or University degree	2.8	8.9	15.4	0.3	-3.5	-3.4	-1.9	-3.2	-3.1	-2.6	-3.2	-2.2	-2.6	-3.2	-3.4	-3.3	-3.9	-2.8	-3.4	-3.3	-2.7	-2.5	-2.9	-2.4	-3.9	-2.4	-3.4
Qualifications: CSEs or equivalent	2.7	3.6	6.7	1.5	2.4	1.8	1.4	2.0	1.4	1.2	1.2	1.9	1.4	2.6	2.2	2.5	1.5	1.6	2.3	1.7	1.7	1.4	2.2	1.6	2.2	2.2	2.3
Pulse rate	2.7	4.5	8.2	1.4	-2.2	-2.2	-0.9	-2.3	-2.3	-2.3	-2.4	-2.0	-2.3	-2.1	-2.1	-2.2	-2.1	-2.0	-2.3	-2.4	-2.1	-1.9	-2.1	-2.9	-1.7	-1.8	-2.1
Pulse wave peak to peak time	2.7	3.1	5.3	1.6	-1.6	-1.6	-1.1	-1.8	-2.2	-2.3	-2.2	-2.0	-1.8	-1.5	-1.7	-1.6	-1.8	-2.1	-1.6	-2.1	-1.8	-1.8	-1.6	-1.4	-2.0	-0.9	-1.5
Bipolar Disorder or Schizophrenia	2.6	6.4	9.0	-0.5	-2.9	-2.5	-1.4	-2.6	-2.5	-2.2	-2.5	-2.0	-2.4	-3.0	-2.9	-3.0	-2.0	-2.9	-3.0	-2.6	-2.3	-2.5	-2.8	-3.0	-2.4	-2.9	-2.7
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	4.6	1.7	-1.7	-2.0	-1.2	-2.0	-1.8	-1.6	-2.0	-0.8	-1.7	-1.6	-1.7	-1.7	-2.1	-1.6	-1.9	-2.0	-2.0	-1.6	-1.6	-1.7	-1.9	-1.6	-1.9
Impedance of leg (left)	2.6	12.9	21.6	0.4	-4.2	-3.3	-2.3	-3.6	-3.8	-4.1	-3.9	-4.7	-3.6	-3.7	-4.1	-3.8	-4.1	-4.1	-3.9	-4.0	-2.9	-3.1	-3.4	-3.7	-3.7	-2.0	-3.1
Vascular/heart problems diagnosed by doctor	2.5	6.7	10.6	2.0	-2.0	-2.3	-3.0	-2.8	-3.2	-2.7	-3.0	-0.1	-2.3	-2.2	-2.4	-2.3	-2.2	-2.7	-2.4	-2.8	-3.3	-2.9	-3.1	-3.1	-1.9	-3.1	-2.3
Medication: Omeprazole (e.g. Zanprol)	2.5	3.1	5.8	0.7	2.0	1.6	0.7	1.8	1.8	1.3	1.7	1.5	2.0	2.1	2.0	2.1	1.8	1.9	2.1	1.8	1.6	1.3	1.8	1.2	2.4	1.7	1.9
Lung FVC	2.4	12.4	22.8	2.7	4.4	3.0	3.2	3.0	3.2	2.8	3.2	2.7	3.2	4.1	4.1	4.0	4.8	3.4	4.2	3.1	2.0	4.6	3.2	3.4	3.7	3.2	3.9
High blood pressure (mother)	2.4	3.4	5.4	0.1	2.2	1.7	0.2	2.1	1.7	1.4	1.7	1.6	1.4	2.2	2.0	2.2	2.0	1.6	2.1	1.9	2.0	1.4	2.0	2.0	2.1	2.2	2.3
Pulse rate, automated reading	2.4	7.7	13.7	1.1	-3.0	-3.1	-1.4	-3.2	-3.0	-2.8	-3.1	-2.8	-2.3	-2.9	-2.8	-2.9	-3.7	-2.5	-3.2	-3.2	-2.8	-1.8	-2.2	-2.7	-3.2	-2.1	-3.2
Tinnitus: Yes, now most or all of the time	2.4	2.8	4.5	-0.6	1.7	2.0	1.6	1.9	1.2	1.4	1.6	1.1	1.5	1.8	1.6	1.9	1.1	1.3	1.7	1.7	2.0	2.1	1.9	1.9	1.4	2.1	1.8
Pulse wave Arterial Stiffness index	2.3	2.6	4.5	-1.6	1.4	1.5	1.1	1.6	2.0	2.1	2.0	1.8	1.6	1.3	1.6	1.4	1.6	2.0	1.4	1.9	1.7	1.7	1.4	1.3	1.8	0.7	1.4
Breastfed as a baby	2.3	2.8	10.5	-3.2	0.8	1.9	2.5	1.8	1.8	1.8	2.0	0.4	2.1	0.9	1.0	1.1	1.8	1.3	1.2	2.0	2.3	0.9	1.4	0.6	1.9	1.1	1.2
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	8.7	-0.7	-2.0	-1.4	-0.0	-1.6	-1.2	-1.6	-1.4	-2.9	-0.4	-1.8	-1.7	-1.8	-3.0	-1.2	-1.8	-1.6	-1.0	-2.1	-1.3	-1.5	-2.0	-0.9	-1.8
Risk taking	2.3	3.4	6.2	1.5	-1.7	-2.4	-1.0	-2.3	-1.8	-1.7	-2.0	-1.4	-1.5	-1.9	-1.6	-1.9	-1.4	-1.4	-1.8	-2.2	-2.3	-2.4	-1.7	-2.5	-1.4	-1.6	-2.0
Supplements: Fish oil (including cod liver oil)	2.2	2.9	4.9	0.8	2.0	1.3	0.4	1.7	1.9	1.6	1.8	1.2	1.3	1.8	2.1	1.8	2.2	2.0	1.9	1.7	1.4	1.8	1.7	2.1	1.7	1.6	2.0
Impedance of leg (right)	2.1	10.4	15.8	0.8	-3.6	-3.0	-2.3	-3.4	-3.5	-3.6	-3.5	-3.7	-3.1	-3.3	-3.5	-3.4	-4.0	-3.5	-3.4	-3.6	-2.8	-3.0	-3.0	-3.3	-3.4	-1.7	-2.9
Fluid intelligence score	2.1	4.5	7.9	2.0	-1.6	-2.4	-2.8	-2.4	-2.2	-1.7	-2.4	-0.4	-2.5	-2.0	-1.8	-2.1	-2.2	-1.6	-2.1	-2.2	-2.6	-1.9	-2.0	-1.6	-2.3	-2.2	-2.3
Family relationship satisfaction	2.1	2.5	6.6	0.1	-1.5	-1.3	-2.6	-1.3	-1.7	-1.9	-1.6	-0.9	-1.7	-1.4	-1.7	-1.5	-1.3	-2.1	-1.5	-1.5	-1.4	-1.9	-2.0	-2.1	-0.8	-1.6	-1.0
Diabetes (self-reported)	2.0	3.1	5.8	0.8	2.2	1.1	1.3	1.5	1.7	1.8	1.8	1.8	1.8	2.0	2.1	2.0	1.5	2.0	2.0	1.7	1.1	2.1	1.9	2.4	1.2	1.7	1.5
Number of full brothers	2.0	2.5	4.4	1.2	-1.4	-1.8	-1.6	-2.0	-1.3	-1.2	-1.5	-0.8	-1.8	-1.6	-1.2	-1.7	-1.6	-0.7	-1.7	-1.6	-2.1	-2.0	-1.4	-1.1	-1.7	-1.9	-1.7
Number of operations (self-reported)	2.0	3.0	6.1	0.4	-1.7	-1.4	-2.2	-1.7	-1.9	-1.8	-1.9	-0.6	-1.8	-1.8	-1.9	-1.8	-0.6	-1.9	-1.8	-1.8	-2.0	-1.2	-2.2	-1.9	-1.6	-2.5	-1.8
Diastolic blood pressure, automated reading	2.0	6.2	10.2	-2.6	1.9	3.2	3.0	2.7	2.7	2.5	2.6	0.7	2.7	2.1	2.1	2.2	2.2	2.2	2.3	2.7	3.2	2.7	2.9	2.5	2.0	2.8	2.0
Verbal and Numeric Reasoning (VNR)	1.9	4.5	10.1	0.4	-1.9	-2.1	-3.2	-2.1	-2.1	-1.6	-2.1	-0.6	-2.8	-2.3	-2.1	-2.3	-1.6	-2.1	-2.2	-2.0	-2.2	-1.9	-2.5	-1.6	-2.4	-2.6	-2.3
Systolic blood pressure, automated reading	1.9	5.5	8.4	-1.5	2.0	2.8	2.9	2.4	2.8	2.6	2.6	0.5	2.3	2.1	2.2	2.1	2.5	2.3	2.3	2.5	2.6	2.6	2.6	2.5	2.0	2.5	2.1
Taking other prescription medications	1.9	2.9	4.1	-0.5	1.8	1.6	1.0	1.8	1.8	1.8	2.0	1.3	1.7	1.7	1.8	1.8	2.0	1.8	1.8	1.9	1.6	1.8	1.9	1.8	1.8	1.4	1.6
Past tobacco smoking	1.9	3.5	8.4	0.6	-2.2	-1.7	-0.3	-2.2	-1.8	-2.0	-1.7	-2.9	-1.6	-1.9	-2.0	-2.1	-1.9	-1.6	-1.9	-2.1	-1.9	-2.3	-1.6	-2.0	-1.9	-0.9	-1.8
Medication: Simvastatin	1.9	2.8	6.7	-1.3	1.3	1.4	2.2	1.6	2.0	1.8	1.8	-0.1	2.0	1.3	1.6	1.5	1.6	1.8	1.6	1.7	2.0	1.2	2.3	1.5	1.5	2.6	1.3
Time employed in main current job	1.9	2.2	4.4	-0.2	1.7	1.6	1.0	1.6	1.0	1.3	1.4	1.2	1.3	1.7	1.6	1.7	0.7	1.1	1.6	1.4	1.6	1.4	1.7	2.1	1.1	2.1	1.7
Tense / ‘highly strung’	1.9	3.2	5.4	1.9	-1.3	-1.9	-2.0	-2.1	-2.1	-1.7	-2.2	-0.4	-1.9	-1.5	-1.5	-1.7	-1.8	-1.6	-1.8	-2.1	-2.3	-1.3	-1.7	-1.8	-1.7	-1.8	-1.9
High blood pressure	1.8	5.1	8.4	-2.1	1.6	2.0	2.5	2.4	2.9	2.3	2.8	-0.0	1.9	1.8	2.0	1.9	1.9	2.4	2.1	2.4	2.9	2.7	2.6	2.7	1.6	2.6	2.0
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	4.2	-0.0	-1.7	-1.2	-1.8	-1.3	-1.6	-1.4	-1.5	-0.8	-1.6	-1.6	-1.8	-1.6	-1.5	-1.8	-1.7	-1.5	-1.1	-1.7	-1.8	-2.0	-0.9	-1.2	-1.0
Wheeze or whistling in the chest in last year	1.8	3.2	6.4	0.7	2.2	1.9	0.3	1.9	1.4	1.6	1.4	2.5	1.4	2.1	1.9	2.2	2.2	1.4	2.1	1.8	1.5	1.6	1.9	1.3	2.3	1.6	1.9
Medication: Ibuprofen	1.8	2.1	3.6	-1.0	-1.8	-1.5	-1.3	-1.4	-1.3	-1.4	-1.3	-1.7	-1.3	-1.9	-1.8	-1.8	-0.7	-1.7	-1.7	-1.3	-1.3	-0.4	-1.7	-1.3	-1.6	-1.5	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.3	0.4	1.7	1.1	1.1	1.4	1.4	1.7	1.5	2.1	1.2	1.7	1.5	1.7	1.9	1.3	1.8	1.6	0.9	0.7	1.1	1.3	1.8	0.9	1.6
Myopia	1.8	2.6	6.5	2.5	-1.1	-1.7	-1.6	-1.8	-1.5	-1.9	-1.6	-1.1	-1.3	-1.1	-1.1	-1.2	-1.8	-0.9	-1.4	-1.8	-2.1	-2.3	-1.4	-1.3	-1.4	-1.6	-1.5
Current tobacco smoking	1.7	2.7	9.6	3.1	2.3	0.8	-0.3	1.1	1.2	1.2	1.0	2.2	0.6	2.1	2.1	1.9	1.8	1.8	1.9	1.1	0.4	1.8	1.6	2.0	1.3	1.0	1.6
Hypertension (Self-reported)	1.7	4.9	8.2	-2.4	1.6	2.0	2.4	2.4	2.8	2.3	2.7	0.1	1.8	1.7	1.9	1.9	1.8	2.2	2.0	2.4	2.9	2.8	2.6	2.7	1.4	2.4	1.8
Unable to work because of sickness or disability	1.7	2.2	3.4	-0.6	1.4	1.3	1.8	1.5	1.8	1.9	1.7	1.1	1.5	1.3	1.6	1.4	1.5	1.8	1.5	1.6	1.6	1.2	1.7	1.5	1.4	1.5	1.3
Chronotype (morning person)	1.6	3.7	7.6	1.0	-2.0	-1.5	-0.2	-2.4	-2.0	-2.0	-2.0	-1.6	-1.2	-1.8	-1.9	-1.9	-2.8	-1.7	-2.0	-2.3	-2.1	-2.4	-1.6	-2.3	-2.0	-1.6	-2.2
Had other major operations	1.6	1.9	4.0	0.9	-1.4	-1.2	-1.3	-1.5	-1.5	-1.4	-1.4	-0.8	-1.2	-1.5	-1.4	-1.5	-0.4	-1.5	-1.5	-1.4	-1.6	-1.1	-1.7	-1.6	-1.1	-2.0	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.7	5.7	-0.2	-1.8	-1.8	-0.8	-1.6	-1.9	-1.5	-1.9	-1.1	-1.5	-1.8	-1.9	-1.8	-1.5	-1.9	-1.7	-1.7	-1.4	-1.8	-1.5	-2.4	-1.2	-1.2	-1.7
Pain all over the body in last month	1.5	1.6	3.8	0.7	-1.6	-1.3	-0.1	-1.4	-1.1	-1.4	-1.2	-1.9	-1.0	-1.4	-1.4	-1.5	-1.0	-1.1	-1.4	-1.4	-1.0	-1.1	-0.8	-1.7	-1.2	-0.6	-1.5
Comparative body size at age 10	1.5	4.2	9.8	1.0	2.3	1.9	1.9	1.8	2.3	2.2	2.1	2.0	1.6	2.2	2.3	2.2	3.1	2.5	2.3	2.0	1.3	1.5	2.0	2.1	2.2	1.5	1.9
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	3.9	-0.9	-1.7	-1.1	-1.3	-1.0	-1.2	-1.7	-1.1	-1.8	-2.0	-1.5	-1.7	-1.4	-0.6	-1.7	-1.5	-1.1	-0.9	-0.1	-1.8	-1.0	-1.3	-1.7	-1.0
Alcohol intake versus 10 years previously	1.4	2.1	3.7	-1.4	1.2	1.6	1.1	1.5	1.6	1.9	1.7	1.8	1.9	1.2	1.3	1.4	0.5	1.6	1.3	1.7	1.6	1.5	1.6	1.6	1.1	1.1	1.1
Falls in the last year	1.4	1.9	12.4	0.5	-0.8	-0.7	-3.5	-0.7	-1.5	-1.5	-1.3	0.5	-2.0	-0.8	-1.3	-0.8	-0.9	-2.0	-1.1	-1.0	-1.0	-1.2	-1.6	-1.0	-0.9	-1.8	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.7	2.8	-0.1	-1.4	-1.4	-1.5	-1.2	-1.2	-1.4	-1.3	-1.4	-1.5	-1.6	-1.4	-1.5	-0.5	-1.5	-1.3	-1.2	-1.3	-0.9	-1.7	-1.5	-1.0	-1.4	-1.2
Prospective memory result	1.4	1.8	9.5	-3.1	0.5	1.8	1.2	1.6	1.7	1.1	1.5	0.2	1.0	0.6	0.6	0.8	1.7	0.7	0.9	1.6	2.0	1.0	0.6	0.8	1.3	0.5	1.3
Smoking status: Previous	1.4	2.2	4.4	-1.9	1.4	1.5	0.9	1.9	1.5	1.5	1.4	1.5	1.5	1.3	1.3	1.5	1.2	1.2	1.4	1.8	2.1	1.4	1.5	1.2	1.6	1.0	1.3
Smoking status: Current	1.4	2.2	9.6	3.1	2.0	0.5	-0.5	0.8	1.1	1.1	0.9	2.1	0.5	1.8	1.9	1.6	1.8	1.6	1.6	0.9	-0.0	1.9	1.2	1.9	1.0	0.6	1.3
Alzheimer’s Disease (in mother)	1.3	1.5	6.2	2.4	-0.6	-2.0	-0.9	-1.5	-0.6	-0.7	-1.0	-0.6	-0.9	-0.8	-0.5	-0.9	-0.6	-0.2	-0.8	-1.3	-1.9	-2.5	-0.9	-1.6	-0.3	-1.0	-0.9
Systolic Blood Pressure	1.3	6.6	14.2	-1.2	2.1	3.1	3.8	2.6	2.7	2.5	2.8	-0.1	2.5	2.1	2.4	2.2	2.5	2.4	2.3	2.7	3.0	3.1	2.9	3.1	1.8	3.0	2.4
Ever smoked	1.3	2.3	6.3	0.0	1.8	1.2	-0.2	1.8	1.4	1.6	1.3	2.5	1.3	1.7	1.7	1.8	1.4	1.5	1.6	1.7	1.4	1.9	1.5	1.9	1.3	0.7	1.3
Body Mass Index (BMI) (2010)	1.2	1.7	5.4	-2.3	0.6	1.1	1.8	1.4	1.6	1.6	1.5	0.2	1.5	0.9	0.9	0.9	0.9	1.3	1.1	1.4	1.8	0.0	1.5	0.4	1.4	1.5	0.9
Neuroticism score	1.2	2.5	4.3	-0.2	1.8	1.4	0.6	1.7	1.5	1.5	1.4	1.6	1.5	1.8	1.8	1.8	1.3	1.6	1.8	1.6	1.6	1.2	1.9	1.1	2.0	2.1	1.7
Illnesses of mother	1.2	1.5	3.3	-0.7	-1.6	-0.8	0.3	-1.3	-1.4	-1.2	-1.1	-1.8	-0.1	-1.4	-1.5	-1.4	-1.5	-1.2	-1.4	-1.3	-0.9	-0.4	-1.0	-1.0	-1.7	-0.7	-1.5
Pain experienced in last month	1.2	2.0	5.0	-1.7	-1.8	-1.3	-0.6	-1.2	-0.7	-1.0	-0.8	-1.8	-1.5	-1.8	-1.5	-1.7	-2.2	-0.7	-1.7	-1.1	-0.8	-1.8	-1.3	-1.0	-1.7	-1.4	-1.6
Alcohol drinker status: Previous	1.2	1.4	3.4	1.5	1.3	1.2	0.3	0.8	0.7	1.0	0.7	1.8	1.4	1.4	1.2	1.3	1.3	1.0	1.2	0.7	0.6	1.4	1.4	1.4	0.6	1.3	1.0
Schizophrenia vs Biploar Disorder	1.1	1.4	5.9	-2.4	0.8	1.4	1.3	1.5	1.2	1.1	1.3	-0.2	0.8	0.9	0.9	1.0	0.7	0.7	1.1	1.4	1.8	0.2	1.2	0.3	1.6	1.4	1.0
Fasting Glucose	1.1	1.4	2.5	-0.3	-1.6	-0.7	0.6	-0.8	-1.2	-1.2	-1.3	-1.3	-0.7	-1.6	-1.6	-1.5	-1.2	-1.4	-1.5	-1.2	-0.4	-0.9	-0.9	-1.4	-1.1	-0.9	-1.4
Medication for hormone replacement therapy	1.1	1.3	2.6	-0.2	1.1	0.8	0.9	1.0	1.6	1.3	1.2	0.6	1.0	1.1	1.2	1.1	1.3	1.4	1.3	1.2	0.7	1.0	0.9	1.1	1.4	1.0	1.5
Serious illness, injury or assault to yourself	1.1	1.3	4.8	1.2	1.5	0.9	-0.3	1.0	0.5	0.6	0.7	2.2	0.6	1.3	1.1	1.3	2.0	0.5	1.2	0.9	0.4	1.9	0.5	1.1	1.1	0.2	1.2
Peak expiratory flow (PEF)	1.1	2.6	5.1	1.3	-1.6	-2.3	-1.1	-1.9	-1.7	-1.9	-1.7	-1.4	-1.1	-1.6	-1.5	-1.7	-1.9	-1.2	-1.6	-1.9	-1.8	-1.7	-1.5	-2.0	-1.4	-1.2	-1.6
Gout (self-reported)	1.1	1.6	3.0	0.2	-1.2	-1.5	-1.3	-1.2	-1.4	-1.2	-1.2	-0.8	-1.7	-1.4	-1.2	-1.4	-0.9	-1.3	-1.3	-1.2	-1.3	-1.1	-1.6	-0.9	-1.4	-1.5	-1.2
Mood swings	1.1	2.0	3.6	0.8	1.9	1.3	0.4	1.6	1.3	0.9	1.3	0.6	0.7	1.8	1.8	1.8	1.7	1.4	1.7	1.4	1.1	1.3	1.4	1.6	1.7	1.2	1.7
Friendships satisfaction	1.1	1.3	4.6	-0.3	-1.3	-1.1	-1.5	-1.0	-1.1	-1.1	-1.0	-0.6	-0.7	-1.0	-1.3	-1.1	-2.2	-1.0	-1.2	-1.1	-0.8	-1.7	-1.0	-1.6	-0.8	-0.7	-1.0
Mother’s age at death	1.1	1.3	3.5	-0.5	-1.3	-0.9	-1.5	-0.9	-0.9	-0.8	-1.0	-0.1	-1.6	-1.2	-1.4	-1.2	-0.6	-1.4	-1.2	-0.9	-1.0	-1.3	-1.5	-1.2	-0.9	-1.9	-1.3
Ulcerative Colitis (UC)	1.0	1.9	3.3	-1.0	-1.7	-1.4	-0.4	-1.3	-1.0	-0.7	-1.1	-1.0	-1.3	-1.8	-1.6	-1.8	-1.2	-1.3	-1.6	-1.2	-1.3	-1.0	-1.8	-1.6	-1.4	-1.8	-1.7
Ulcerative Colitis	1.0	1.4	3.4	0.2	-1.0	-1.4	-1.3	-1.2	-1.0	-0.4	-1.0	0.3	-1.5	-1.4	-1.0	-1.3	-0.6	-0.8	-1.2	-1.1	-1.5	-1.2	-1.5	-1.4	-0.9	-1.9	-1.4
Diabetes (mother)	1.0	1.3	2.3	-0.1	-1.0	-1.4	-1.1	-1.0	-1.1	-1.4	-1.0	-1.5	-1.3	-1.0	-1.1	-1.0	-1.5	-1.2	-1.1	-1.0	-1.1	-1.4	-1.0	-1.2	-0.8	-1.1	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	4.2	-0.1	-1.6	-0.8	-0.7	-1.6	-1.5	-1.4	-1.3	-1.2	-0.3	-1.6	-1.6	-1.5	-2.0	-1.4	-1.6	-1.6	-1.4	-2.1	-1.5	-1.7	-1.6	-1.6	-1.8
Chronic bronchitis/emphysema (father)	1.0	1.2	4.4	-0.4	1.0	1.3	0.6	1.1	1.1	1.2	1.1	1.1	0.7	0.9	1.1	1.0	2.1	1.1	1.1	1.2	1.1	0.5	1.0	0.2	1.8	0.9	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.6	1.4	1.3	0.8	1.4	0.5	1.1	0.7	0.8	-0.1	1.2	1.2	1.6	1.2	0.4	1.9	1.2	0.7	0.5	0.9	1.8	1.2	0.5	1.5	0.5
Diabetes diagnosed by doctor	1.0	1.6	3.4	0.9	1.6	0.4	0.9	0.9	1.4	1.4	1.2	1.4	1.2	1.3	1.7	1.4	0.8	1.8	1.4	1.2	0.5	1.3	1.4	1.8	0.7	1.1	0.9
Financial situation satisfaction	1.0	1.2	3.4	-0.2	-0.9	-0.7	-1.7	-0.8	-1.1	-1.0	-1.1	-0.3	-1.8	-1.2	-1.1	-1.1	-0.4	-1.5	-1.0	-0.9	-1.0	-1.4	-1.5	-1.4	-0.4	-1.4	-0.6
Cholesterol lowering medication	1.0	1.4	3.7	-0.4	0.9	0.7	1.9	0.9	1.4	1.3	1.2	-0.1	1.9	1.0	1.2	1.0	0.6	1.6	1.1	1.1	1.2	0.7	1.9	1.1	0.7	1.7	0.4
Schizophrenia (2018)	0.9	1.9	3.3	-1.1	-1.6	-1.0	-0.9	-1.2	-1.2	-1.1	-1.0	-1.2	-1.5	-1.7	-1.7	-1.6	-0.8	-1.6	-1.6	-1.2	-1.1	-1.3	-1.6	-1.8	-1.0	-1.8	-1.4
Major Depression (MDD)	0.9	1.0	2.6	-0.2	-1.1	-0.6	-0.6	-1.0	-1.2	-0.8	-1.1	-0.4	-1.6	-1.2	-1.2	-1.0	-0.9	-1.2	-1.2	-1.0	-0.9	-0.9	-1.0	-0.9	-1.3	-1.0	-1.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.2	1.2	-1.0	-1.2	-0.7	-1.4	-0.9	-0.9	-0.9	-0.8	-0.5	-1.0	-0.9	-1.0	-0.9	-0.6	-1.2	-1.3	-1.5	-0.0	-1.0	-0.6	-1.4	-1.1	-1.0
Trunk fat percentage	0.9	3.5	11.1	-2.0	-2.3	-1.8	0.6	-1.9	-1.2	-1.2	-1.5	-3.3	-0.7	-2.1	-2.0	-2.1	-2.9	-1.4	-2.0	-1.7	-1.2	-2.1	-0.7	-1.5	-2.3	-0.4	-2.4
Asthma	0.9	1.7	5.2	0.2	1.6	1.8	0.1	1.5	0.9	1.0	1.0	1.5	0.1	1.4	1.2	1.5	2.3	0.5	1.5	1.3	1.0	1.4	0.6	0.7	2.1	0.6	1.9
Loud music exposure frequency	0.9	0.9	2.0	1.2	-0.8	-0.8	-0.7	-1.1	-1.1	-0.9	-1.2	0.1	-1.4	-0.8	-1.0	-0.9	-0.1	-1.1	-0.9	-1.1	-1.3	-0.1	-1.2	-0.6	-1.1	-1.2	-0.9
Medication: Omeprazole	0.9	1.0	1.9	0.5	1.0	0.8	0.4	1.1	1.1	0.8	0.9	1.1	1.3	1.3	1.0	1.2	1.1	1.0	1.2	1.0	1.0	1.0	1.0	0.6	1.4	0.9	1.1
Illnesses of father: None of the above (group 1)	0.9	1.1	3.5	-0.2	-0.9	-1.2	-1.0	-1.0	-0.9	-0.4	-0.9	0.2	-1.6	-1.1	-1.0	-1.1	-0.7	-1.0	-1.1	-0.8	-1.2	-0.2	-1.6	-0.4	-1.2	-1.9	-1.0
Medication: Paracetamol	0.9	1.5	2.7	-0.8	-1.5	-1.2	-1.0	-1.2	-1.0	-0.9	-1.2	-1.3	-1.6	-1.6	-1.4	-1.6	-0.9	-1.3	-1.4	-1.2	-1.2	-0.1	-1.5	-0.4	-1.6	-0.9	-0.9
Depression (Nagel 2018)	0.8	1.1	2.3	-1.1	-1.3	-0.9	-1.0	-0.9	-0.6	-0.6	-0.7	-1.4	-1.5	-1.3	-1.2	-1.3	-0.6	-1.0	-1.1	-0.9	-0.8	-1.3	-1.2	-1.5	-0.6	-1.1	-0.9
Had menopause	0.8	1.0	1.9	-0.2	0.9	1.1	-0.1	1.0	1.1	0.8	1.1	0.4	1.1	1.1	1.0	1.1	1.4	1.1	1.1	0.9	1.1	1.0	1.1	0.9	1.1	1.3	1.2
Qualifications: None of the above	0.8	1.8	4.3	-0.1	1.4	1.5	1.6	1.2	1.6	1.4	1.4	1.2	1.1	1.3	1.4	1.3	2.1	1.2	1.5	1.4	0.9	1.1	1.3	0.9	1.6	1.0	1.2
Heart attack	0.8	1.0	6.1	0.8	1.0	0.4	2.5	0.6	0.9	1.1	0.7	0.9	1.2	0.9	1.1	0.9	0.6	1.3	1.0	0.7	0.6	0.2	1.5	0.4	0.8	1.3	0.3
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.2	-0.9	-1.7	-1.3	-1.2	-1.2	-1.2	-0.8	-1.1	-0.7	-1.3	-1.7	-1.6	-1.7	-1.1	-1.3	-1.6	-1.2	-0.9	-0.9	-1.6	-1.0	-1.8	-1.6	-1.6
Standing height	0.8	7.6	10.1	1.3	-2.6	-3.2	-2.4	-3.0	-3.0	-3.1	-3.0	-2.4	-2.5	-2.8	-2.8	-2.8	-2.8	-2.7	-2.9	-3.0	-3.0	-2.6	-2.9	-2.4	-2.9	-2.8	-2.7
Exposure to tobacco smoke at home	0.8	0.9	1.7	-0.0	1.0	1.0	1.0	1.0	1.1	0.9	1.1	0.3	1.0	0.9	1.0	1.0	1.1	1.1	1.0	1.0	0.8	1.0	1.0	1.3	0.8	0.8	0.9
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.0	1.2	-0.6	-1.1	-1.4	-0.9	-1.2	-1.0	-1.2	0.5	-1.3	-0.7	-0.9	-0.7	-0.9	-1.3	-0.8	-1.0	-1.1	-0.4	-1.0	-0.8	-1.0	-0.9	-0.9
Exposure to tobacco smoke outside home	0.8	1.1	4.1	1.0	0.9	0.4	2.0	0.6	1.1	1.0	1.0	0.1	1.1	1.0	1.1	0.9	1.6	1.4	1.0	0.8	0.4	0.9	1.1	0.9	0.9	0.9	0.8
Handedness (chirality/laterality): Left-handed	0.8	0.9	4.1	-1.0	0.2	0.6	2.0	0.6	1.1	1.2	0.9	-0.1	1.8	0.3	0.6	0.4	-0.5	1.5	0.3	0.8	1.2	0.3	1.3	1.2	-0.3	0.9	-0.1
Commuting to job workplace: Walk	0.8	0.9	2.8	-1.2	-0.9	0.0	-1.6	-0.3	-1.0	-1.1	-0.8	-0.2	-1.2	-1.0	-1.2	-0.9	-0.1	-1.7	-0.8	-0.5	-0.3	-0.4	-1.4	-1.3	-0.2	-1.2	-0.4
Guilty feelings	0.8	1.2	2.1	0.2	1.3	0.9	0.3	1.0	1.1	1.2	1.0	1.5	0.8	1.2	1.3	1.1	1.0	1.3	1.2	1.1	0.9	0.5	1.1	0.9	1.4	1.2	1.2
Commuting to job workplace: Cycle	0.8	1.0	1.9	-0.8	-1.3	-0.6	0.0	-1.0	-0.6	-0.6	-0.7	-1.0	-1.2	-1.2	-1.2	-1.2	-0.6	-0.8	-1.0	-0.8	-0.9	-1.3	-0.9	-1.4	-0.7	-1.0	-1.3
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.6	0.8	1.0	0.4	2.4	0.6	0.9	1.1	0.7	0.9	1.2	1.0	1.1	1.0	0.6	1.3	1.0	0.7	0.7	0.2	1.6	0.4	0.9	1.4	0.4
Alzheimer’s Disease (including proxy)	0.7	1.1	5.2	2.3	-0.6	-1.7	-0.1	-1.4	-0.3	-0.6	-0.7	-0.9	-0.2	-0.5	-0.4	-0.7	-0.0	0.1	-0.5	-1.1	-1.6	-2.3	-0.4	-1.5	-0.2	-0.5	-0.9
Age at First Birth	0.7	1.0	2.2	0.5	-1.0	-1.0	-0.4	-1.0	-0.9	-1.1	-0.9	-0.4	-0.6	-1.1	-1.1	-1.0	-1.5	-1.1	-1.1	-1.0	-0.9	-0.6	-1.0	-0.4	-1.5	-1.2	-1.1
HDL Cholesterol	0.7	1.2	3.2	0.2	1.2	1.2	0.8	1.2	0.9	0.8	1.0	0.7	0.6	1.2	1.1	1.2	1.4	0.7	1.1	1.1	1.2	1.8	0.9	1.6	0.7	1.1	1.5
Hand grip strength (left)	0.7	2.0	3.9	-0.2	1.8	0.9	-0.2	1.6	1.4	1.3	1.7	2.0	0.9	1.7	1.6	1.7	1.0	1.4	1.7	1.6	1.4	1.0	1.0	1.3	1.7	0.9	1.7
Frequency of depressed mood in last 2 weeks	0.7	0.9	3.4	-0.2	-0.8	-0.9	-1.9	-0.6	-0.7	-0.8	-0.8	-0.4	-1.6	-0.9	-1.0	-1.0	-0.4	-1.3	-0.9	-0.7	-0.8	-1.0	-1.3	-0.9	-0.4	-1.4	-0.5
Stomach or abdominal pain in last month	0.7	0.9	3.0	1.0	-0.8	-0.6	-1.0	-0.9	-1.2	-0.9	-1.0	-0.1	-0.3	-0.6	-0.9	-0.7	-0.4	-1.1	-0.8	-1.0	-1.0	-1.3	-0.9	-1.7	-0.3	-1.0	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	5.3	-0.7	-1.5	-0.4	0.4	-1.2	-1.0	-0.8	-0.7	-1.2	-0.1	-1.4	-1.3	-1.3	-1.7	-0.9	-1.4	-1.1	-0.8	-2.3	-1.0	-1.7	-1.2	-1.2	-1.7
Illnesses of siblings	0.7	1.0	2.8	-1.1	0.8	1.4	-0.2	1.3	0.7	0.9	1.1	1.7	0.3	0.9	0.6	0.9	1.2	0.2	0.9	1.2	1.0	1.5	0.2	1.2	0.9	0.0	1.2
Length of working week for main job	0.7	0.8	1.7	-0.3	1.0	0.9	1.1	1.2	0.7	0.5	0.9	0.2	0.2	0.9	0.9	1.1	0.6	0.7	0.9	0.9	1.3	0.7	0.9	0.9	1.0	1.1	1.3
Medication: Paracetamol	0.7	1.2	2.5	-0.5	-1.2	-1.1	-1.6	-1.0	-1.0	-1.1	-1.1	-1.2	-1.6	-1.3	-1.2	-1.3	-0.7	-1.3	-1.1	-1.1	-1.1	0.1	-1.4	-0.4	-1.3	-0.7	-0.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.5	2.3	-0.2	1.5	1.2	0.2	1.4	1.2	1.2	1.3	1.3	1.4	1.3	1.4	1.3	1.3	1.2	1.3	1.4	1.1	1.2	1.1	1.2	1.3	0.7	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.4	0.2	1.0	0.4	0.3	0.8	1.4	1.5	1.0	1.5	0.2	0.7	1.1	0.8	0.8	1.5	0.9	1.1	0.7	0.4	0.9	0.9	1.0	0.6	0.6
Number of full sisters	0.7	0.9	1.9	0.7	-0.8	-1.1	-0.6	-1.1	-0.9	-0.7	-1.0	0.1	-1.0	-1.0	-0.9	-1.0	-0.5	-0.7	-0.9	-1.0	-1.4	-1.1	-1.1	-1.4	-0.5	-1.2	-1.0
Chest pain or discomfort	0.7	1.0	3.8	1.9	-0.4	-0.9	-1.7	-1.2	-1.0	-1.4	-1.1	-0.3	-0.8	-0.7	-0.6	-0.7	-0.6	-0.9	-0.7	-1.2	-1.5	-0.6	-1.0	-0.9	-0.8	-0.8	-0.7
Number of self-reported non-cancer illnesses	0.7	1.3	3.2	-1.6	0.8	1.2	1.4	1.2	1.3	1.2	1.2	-0.0	0.9	0.8	0.9	0.9	1.1	1.0	0.9	1.3	1.4	1.8	1.2	1.0	1.0	1.1	0.9
Average weekly champagne plus white wine intake	0.7	1.0	2.8	-0.5	-1.2	-1.3	-0.1	-1.1	-0.4	-0.8	-0.7	-1.1	0.1	-1.2	-1.1	-1.1	-1.4	-0.6	-1.1	-0.9	-0.8	-0.5	-0.9	-0.4	-1.7	-1.4	-1.5
Eye problems/disorders: Glaucoma	0.7	0.9	1.9	0.0	1.1	1.0	-0.1	1.0	0.6	0.9	0.6	1.3	0.8	0.9	0.9	0.9	1.4	0.5	0.9	0.9	1.0	1.4	0.9	0.9	1.0	0.9	1.1
Breast Cancer	0.6	1.4	2.6	-0.7	-1.6	-1.3	-1.0	-1.2	-0.8	-1.0	-0.8	-1.1	-0.9	-1.5	-1.5	-1.5	-1.4	-1.0	-1.4	-1.0	-0.8	-1.0	-1.2	-1.2	-1.3	-0.8	-1.2
Waist Hip Ratio (WHR)	0.6	2.7	6.6	0.1	-1.6	-1.3	-1.8	-1.4	-1.9	-2.2	-1.7	-2.6	-1.9	-1.4	-1.7	-1.5	-1.7	-2.2	-1.5	-1.7	-1.3	-1.8	-1.4	-2.2	-1.1	-0.7	-1.2
Respiratory disease	0.6	1.4	3.3	0.5	1.6	1.6	0.2	1.4	0.7	1.0	0.9	1.8	0.0	1.4	1.2	1.4	1.8	0.6	1.3	1.2	0.8	1.2	0.5	0.9	1.8	0.2	1.6
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.5	0.4	1.0	0.6	1.0	0.6	1.0	0.9	0.9	0.3	1.2	0.9	1.0	0.9	1.0	0.8	1.0	0.7	0.4	0.6	0.8	0.6	1.2	1.2	1.2
Supplements: Zinc	0.6	0.6	2.1	-0.3	-0.6	-0.7	-0.4	-0.6	-0.6	0.0	-0.5	0.5	-1.3	-0.9	-0.7	-0.9	-0.9	-0.8	-0.8	-0.5	-0.8	-0.8	-1.3	-0.3	-0.8	-1.4	-0.6
Diabetes (father)	0.6	0.7	1.4	-0.8	0.7	1.1	0.3	1.0	1.2	1.0	1.0	0.3	0.7	0.9	0.8	0.8	1.0	0.8	0.9	1.0	0.8	0.4	0.5	0.9	1.0	0.4	0.8
Pack years adult smoking proportion	0.6	1.0	2.7	1.6	1.3	0.7	0.8	0.5	0.8	0.9	0.6	1.0	0.5	1.2	1.3	1.1	1.1	1.3	1.1	0.6	0.2	0.3	1.2	0.8	1.1	1.0	0.9
Hand grip strength (right)	0.6	1.8	3.9	-0.3	1.7	0.8	-0.0	1.5	1.3	1.4	1.6	2.0	1.2	1.6	1.4	1.6	0.8	1.1	1.6	1.5	1.1	1.1	0.8	1.3	1.6	0.8	1.6
Number of incorrect matches in round	0.6	0.9	3.4	-0.3	0.8	1.3	1.6	0.9	1.1	0.6	0.7	-0.3	0.5	0.9	0.8	0.8	1.8	0.6	1.1	1.0	0.8	0.5	0.6	-0.2	1.8	0.8	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.5	0.3	-0.9	-1.1	-1.1	-0.9	-0.7	-0.7	-0.8	-0.6	-1.4	-1.0	-0.9	-1.1	-0.0	-1.0	-0.9	-0.9	-1.1	-1.1	-1.2	-1.6	-0.2	-1.4	-0.8
Hair/balding pattern: Pattern 2	0.6	0.7	1.5	-0.8	0.9	0.9	-0.3	1.0	0.8	0.9	1.0	1.1	0.2	0.7	0.8	0.8	0.4	0.7	0.9	1.0	0.9	0.7	0.5	1.2	0.8	0.9	1.2
Mouth/teeth dental problems: Dentures	0.6	1.1	3.1	0.0	0.9	0.9	1.1	0.8	1.4	1.4	0.9	1.0	1.2	0.8	1.0	0.8	1.7	1.2	1.0	1.0	0.7	1.3	1.2	0.7	1.1	0.9	0.9
Depression (self-reported)	0.6	0.7	3.4	1.9	-0.2	-0.8	-0.9	-0.9	-0.7	-1.4	-1.0	-1.4	-0.5	-0.2	-0.3	-0.3	-1.0	-0.4	-0.4	-1.0	-1.2	-0.7	-0.4	-0.3	-0.8	-0.4	-0.6
Body fat percentage	0.6	2.5	7.8	-2.0	-2.0	-1.5	0.9	-1.6	-0.9	-0.7	-1.1	-2.8	-0.3	-1.8	-1.6	-1.8	-2.7	-1.0	-1.7	-1.3	-1.0	-1.9	-0.3	-1.2	-1.9	-0.2	-2.2
Emphysema/chronic bronchitis	0.6	0.7	1.6	0.3	0.9	0.5	0.9	0.6	1.1	1.2	0.6	1.1	0.7	0.8	1.0	0.8	0.4	1.3	0.9	0.8	0.5	0.5	0.6	1.2	0.4	0.5	0.7
Eye problems/disorders: Cataract	0.6	0.7	1.5	0.2	1.1	0.5	-0.0	1.0	0.7	0.9	0.8	1.1	0.7	0.9	1.0	0.9	1.1	0.6	1.0	0.9	0.7	1.0	0.5	0.4	1.2	0.6	1.0
Back pain experienced in last month	0.6	0.9	3.6	1.6	1.4	0.4	-0.5	0.6	0.2	0.6	0.3	1.9	0.5	1.1	1.1	1.1	1.4	0.4	1.1	0.6	-0.0	1.0	0.5	0.7	1.1	0.5	1.0
Asthma (self-reported)	0.6	1.1	4.0	0.5	1.3	1.5	0.1	1.2	0.5	0.7	0.6	1.3	-0.1	1.2	1.0	1.2	2.0	0.1	1.2	1.0	0.7	1.4	0.3	0.5	1.7	0.3	1.6
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.8	-0.4	-0.9	-0.9	-1.3	-0.6	-0.8	-1.0	-0.8	-0.7	-0.8	-0.8	-0.9	-0.8	-1.1	-1.0	-0.9	-0.7	-0.4	-0.9	-0.6	-1.2	-0.5	-0.5	-0.7
Depressed Affect (Nagel 2018)	0.5	1.0	3.0	-0.9	0.8	1.0	0.7	1.1	1.0	1.1	0.9	0.8	1.0	0.9	0.9	0.9	1.1	0.9	1.0	1.0	1.2	0.1	1.0	-0.1	1.7	1.2	1.1
Worry (Nagel 2018)	0.5	1.1	3.7	-0.1	-1.0	-1.0	-1.1	-1.1	-1.2	-1.1	-1.2	-0.8	-1.3	-0.9	-1.0	-1.0	-1.4	-1.0	-1.1	-1.2	-0.9	-1.5	-0.6	-1.9	-0.5	-0.2	-1.0
Schizophrenia (2014)	0.5	1.1	4.5	-2.1	-1.3	-0.2	0.1	-0.7	-0.6	-0.6	-0.4	-1.1	-1.0	-1.4	-1.3	-1.2	-0.4	-1.4	-1.2	-0.7	-0.3	-1.4	-0.9	-1.4	-0.6	-1.1	-1.1
Allergy or Eczema	0.5	1.2	2.9	-1.4	-1.4	-0.5	-1.0	-0.6	-1.0	-0.9	-0.8	-0.7	-1.5	-1.3	-1.6	-1.3	-0.1	-1.7	-1.1	-0.7	-0.6	-0.6	-1.7	-1.3	-0.5	-1.3	-0.7
Number of treatments/medications taken	0.5	1.0	4.2	-1.1	0.7	0.8	0.9	0.9	1.2	0.9	1.1	-0.3	0.5	0.6	0.8	0.7	1.4	0.9	0.7	1.1	0.9	2.0	1.0	1.5	0.4	0.8	0.7
Townsend deprivation index at recruitment	0.5	0.7	4.8	2.2	1.1	-0.2	-1.0	0.2	0.1	0.4	0.1	1.3	0.1	0.9	1.0	0.8	0.2	0.6	0.6	0.2	-0.3	1.1	0.6	1.5	-0.3	-0.0	0.3
Allergy	0.5	1.0	2.7	0.1	-1.1	-1.4	0.3	-1.3	-0.7	-0.6	-0.9	-1.1	0.0	-1.1	-0.8	-1.2	-1.6	-0.2	-1.2	-1.1	-0.9	-1.4	-0.3	-0.6	-1.6	-0.4	-1.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	5.8	2.3	1.1	0.6	-0.7	0.2	-0.1	0.3	0.0	2.4	0.7	1.0	0.8	0.8	0.6	0.4	0.8	0.2	-0.6	0.3	-0.1	0.3	0.8	-0.3	0.6
Worry too long after embarrassment	0.5	0.8	2.7	1.6	1.2	0.5	-0.0	0.6	0.4	0.1	0.5	0.3	0.9	1.1	1.1	1.0	0.7	0.9	1.0	0.5	0.3	0.9	1.0	0.8	0.8	1.3	1.0
Number of children fathered	0.5	0.6	5.9	-2.4	-0.0	0.8	-0.3	0.9	0.5	0.5	0.8	0.2	0.2	0.1	-0.0	0.2	1.1	-0.0	0.2	0.8	1.1	-0.0	-0.1	-0.3	1.1	-0.5	0.5
Medication for pain relief, constipation, heartburn	0.5	0.8	1.6	-0.6	0.9	1.2	1.1	1.0	0.6	0.9	0.9	0.8	1.3	1.0	0.9	1.0	0.0	0.8	0.8	0.8	1.2	-0.1	1.1	0.6	0.8	0.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.1	0.1	-0.8	-1.3	-1.5	-0.9	-1.2	-0.8	-1.0	0.3	-1.1	-1.0	-1.0	-0.9	-1.3	-1.0	-1.0	-0.8	-0.9	-2.0	-1.1	-1.4	-0.5	-1.1	-0.8
Mineral and other dietary supplements	0.5	0.7	1.2	-0.3	-1.1	-0.5	-0.1	-0.9	-0.9	-0.8	-1.0	-0.4	-0.6	-0.9	-1.1	-0.9	-1.0	-0.9	-1.0	-0.9	-0.8	-0.3	-0.8	-0.9	-1.0	-0.9	-1.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.1	-1.5	0.5	0.8	0.1	1.0	1.1	0.9	0.9	0.4	0.4	0.6	0.6	0.6	0.8	0.8	0.7	1.0	1.0	0.5	0.6	0.5	1.1	0.6	0.8
Fractured/broken bones in last 5 years	0.5	0.7	3.9	2.0	-0.1	-1.2	-0.8	-1.0	-1.0	-0.5	-1.0	0.8	-0.7	-0.2	-0.3	-0.3	-0.5	-0.3	-0.4	-1.0	-1.4	-0.2	-0.4	-0.8	-0.5	-0.8	-0.8
Heart disease (siblings)	0.5	0.6	2.4	1.5	-0.7	-1.0	0.1	-0.9	-0.6	-1.0	-0.8	-1.3	-0.3	-0.4	-0.6	-0.5	-0.4	-0.4	-0.5	-0.9	-0.7	-1.5	0.0	-1.1	-0.5	0.2	-0.8
Pack years of smoking	0.5	0.7	2.6	1.6	1.1	0.6	1.0	0.3	0.7	0.8	0.5	0.7	0.4	1.0	1.1	0.9	1.0	1.2	0.9	0.5	0.1	0.1	1.1	0.5	0.9	0.9	0.6
Prostate Cancer	0.4	0.5	2.6	1.6	0.8	-0.0	0.5	0.1	0.6	1.1	0.3	1.2	0.7	0.7	0.8	0.6	0.8	1.0	0.8	0.3	-0.2	-0.4	0.9	0.5	0.5	0.8	0.2
Primary Biliary Cirrhosis	0.4	0.6	1.7	1.3	-0.4	-0.2	-0.9	-0.8	-1.1	-0.9	-0.9	0.3	-0.8	-0.6	-0.6	-0.6	0.4	-1.0	-0.6	-0.9	-1.2	0.7	-1.0	-0.4	-0.7	-1.0	-0.4
Type 2 Diabetes (T2D) (2012)	0.4	0.4	2.1	0.6	-0.8	-1.1	0.2	-0.8	-0.0	-0.2	-0.5	-0.8	0.6	-0.4	-0.4	-0.6	-0.6	0.3	-0.4	-0.6	-0.4	-1.4	0.1	-0.6	-0.6	0.0	-0.9
Height	0.4	7.3	11.5	1.2	-2.7	-3.1	-1.6	-3.1	-2.7	-3.0	-2.9	-3.0	-1.5	-2.7	-2.6	-2.8	-3.1	-2.3	-2.8	-3.0	-2.9	-3.4	-2.3	-2.7	-2.8	-2.3	-3.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.2	-0.8	0.9	0.6	0.9	0.7	0.9	1.4	0.9	1.5	0.8	0.7	0.8	0.8	0.5	0.9	0.9	0.9	0.5	1.2	0.9	1.3	0.2	0.7	0.3
Neuroticism	0.4	1.0	2.7	-0.9	0.9	0.8	0.6	1.0	1.1	1.1	1.0	0.5	0.9	0.9	1.0	1.0	0.8	1.2	1.0	1.0	1.2	0.2	1.3	0.1	1.6	1.6	1.0
Medication: Co-codamol	0.4	0.5	2.0	0.4	0.5	0.4	1.4	0.6	0.8	0.2	0.4	-0.3	1.0	0.7	0.6	0.7	0.3	0.8	0.7	0.5	0.8	0.4	1.1	0.2	0.7	1.2	0.3
Medication: Levothyroxine sodium	0.4	0.7	1.4	0.7	1.2	0.6	-0.4	0.8	0.8	0.7	0.6	1.1	0.8	0.9	1.1	1.0	0.8	1.1	0.8	0.9	0.4	0.9	0.6	0.8	0.9	-0.2	0.6
Body mass index (BMI)	0.4	1.5	3.8	-1.6	0.9	0.8	1.9	0.9	1.6	1.9	1.4	0.6	1.8	0.8	1.1	0.9	0.3	1.7	1.0	1.3	1.0	0.2	1.8	1.2	0.8	1.2	0.3
Trunk fat mass	0.4	1.7	5.1	-1.6	-1.6	-1.4	0.8	-1.4	-0.7	-0.5	-0.9	-2.2	-0.0	-1.5	-1.3	-1.4	-2.2	-0.7	-1.4	-1.1	-0.9	-1.7	-0.2	-0.9	-1.7	-0.2	-1.9
Forced vital capacity (FVC)	0.4	1.6	3.7	1.9	1.7	0.9	0.9	1.0	0.7	0.3	0.9	0.4	1.2	1.6	1.6	1.5	1.5	1.2	1.6	0.9	0.6	1.7	1.2	1.1	1.3	1.4	1.6
Father’s age at death	0.4	0.5	1.6	-1.3	0.6	0.6	-0.6	0.9	1.0	0.8	1.0	0.5	0.1	0.5	0.6	0.5	1.3	0.7	0.7	1.0	0.7	0.2	0.1	0.3	1.1	-0.3	0.7
Number of live births	0.4	0.6	1.4	0.0	-1.2	-0.6	0.0	-1.0	-0.4	-0.4	-0.6	-0.7	-0.4	-1.1	-1.0	-1.1	-0.3	-0.4	-0.9	-0.9	-0.8	-0.8	-0.6	-0.9	-0.9	-0.3	-1.1
Noisy workplace	0.4	0.5	1.2	0.6	1.0	0.6	-1.1	0.8	0.3	0.2	0.4	1.1	-0.0	0.9	0.7	0.8	1.1	0.1	0.8	0.7	0.7	0.6	0.6	0.5	0.8	0.5	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.6	1.2	-0.3	-1.0	-1.9	-0.7	-0.8	-0.5	-0.7	0.7	-1.1	-0.4	-0.5	-0.5	-0.3	-0.7	-0.5	-0.8	-1.0	-0.7	-0.8	-0.9	-0.2	-0.9	-0.3
Blood clot in the leg (DVT)	0.4	0.5	2.6	0.5	-0.4	-0.4	-0.8	-0.5	-1.0	-1.4	-0.9	-0.5	-0.7	-0.2	-0.7	-0.3	-0.1	-1.1	-0.3	-0.7	-0.6	-0.8	-0.5	-1.6	0.2	-0.6	-0.4
Forced vital capacity (FVC), Best measure	0.4	1.5	3.2	1.2	1.6	0.9	1.1	1.2	0.7	0.4	0.9	0.4	1.1	1.4	1.4	1.4	1.8	1.0	1.5	1.0	0.9	1.6	1.0	0.9	1.5	1.3	1.6
Age at first live birth	0.4	0.7	2.1	0.2	-0.4	-0.5	-1.4	-0.5	-1.0	-0.8	-0.8	0.2	-1.3	-0.6	-0.7	-0.6	0.2	-1.1	-0.6	-0.5	-0.8	-1.4	-1.2	-1.5	0.3	-1.4	-0.2
Suffer from ‘nerves’	0.4	0.6	1.9	0.6	0.6	0.7	1.1	0.4	0.5	0.6	0.4	0.8	0.9	0.7	0.7	0.7	1.0	0.9	0.7	0.4	0.5	0.5	1.1	-0.1	0.9	1.4	0.4
Knee pain experienced in last month	0.4	0.6	5.4	2.3	0.4	-0.3	-2.1	-0.2	-0.8	-0.9	-0.7	0.2	-0.6	0.4	0.0	0.2	0.3	-0.6	0.0	-0.5	-0.7	0.2	-0.4	0.5	-0.4	-0.1	0.3
Illnesses of siblings: Diabetes	0.4	0.4	1.1	-0.1	-0.6	-1.1	-0.8	-0.8	-0.4	-0.1	-0.8	-0.1	-0.7	-0.8	-0.5	-0.7	-1.1	-0.2	-0.7	-0.7	-0.6	-1.0	-0.5	-0.7	-0.7	-0.2	-0.7
Osteoporosis (self-reported)	0.4	0.5	1.5	0.2	-0.7	-0.8	-0.7	-0.6	-0.7	-0.8	-0.7	-0.2	-0.5	-0.8	-0.7	-0.7	-0.8	-0.6	-0.8	-0.6	-0.6	-0.1	-0.9	-0.6	-0.8	-1.2	-0.8
Arm fat-free mass (left)	0.4	1.8	4.2	-0.4	1.5	0.7	1.0	1.1	1.7	2.0	1.5	1.8	1.6	1.2	1.6	1.3	0.9	2.0	1.3	1.5	0.9	0.4	1.5	1.5	1.2	0.8	0.9
Irritable Bowel Disease (IBD)	0.3	0.7	1.6	0.1	-1.0	-0.8	-0.5	-0.9	-0.6	-0.5	-0.9	-0.7	-0.9	-1.1	-0.9	-1.1	-0.7	-0.8	-0.9	-0.9	-0.9	-0.4	-1.3	-0.7	-1.0	-1.1	-0.8
Ovarian Cancer	0.3	0.4	1.8	-1.3	0.3	0.7	0.2	0.6	0.6	0.7	0.6	0.9	0.9	0.2	0.3	0.2	0.5	0.3	0.4	0.6	0.7	0.6	0.2	0.9	0.0	0.1	0.4
Coronary Artery Disease (CAD)	0.3	0.3	1.4	-0.0	-0.8	-0.2	0.1	-0.6	-0.4	-0.7	-0.5	-1.2	-0.4	-0.8	-0.7	-0.7	-0.4	-0.5	-0.7	-0.7	-0.4	-0.4	-0.5	-0.7	-0.6	-0.4	-0.6
Crohns Disease (2012)	0.3	0.4	6.0	2.4	0.7	-0.3	-1.0	-0.0	-0.0	-0.1	-0.2	0.3	-0.1	0.5	0.6	0.5	0.0	0.2	0.4	-0.2	-0.4	-0.0	0.0	0.8	0.0	0.3	0.8
Mean Putamen Volume	0.3	0.3	1.3	0.3	0.6	0.4	-0.6	0.5	0.3	0.6	0.3	1.1	0.4	0.7	0.7	0.7	-0.2	0.7	0.5	0.4	0.5	-0.1	0.4	0.7	0.4	0.8	0.9
Lupus	0.3	0.5	1.2	-0.6	0.3	0.4	0.5	0.8	0.9	0.2	0.8	-1.0	0.1	0.7	0.5	0.6	0.3	0.6	0.7	0.7	0.8	0.4	0.5	0.2	1.1	1.1	1.1
Rheumatoid Arthritis	0.3	0.5	1.3	0.2	0.8	0.7	1.0	0.6	0.6	0.5	0.5	0.5	0.8	0.6	0.7	0.7	1.1	0.6	0.8	0.8	0.3	0.9	0.3	1.0	0.4	0.3	0.5
Blood Red Count	0.3	2.9	6.2	-1.1	-1.9	-1.5	-2.0	-1.5	-1.6	-1.3	-1.5	-0.8	-1.4	-2.0	-1.9	-1.9	-1.7	-1.6	-2.2	-1.5	-1.3	-1.5	-1.8	-1.7	-1.7	-2.5	-1.9
Cardiovascular Disease	0.3	0.9	4.0	-2.0	0.1	0.6	1.7	0.9	1.0	0.8	1.1	-1.0	0.8	0.2	0.4	0.3	0.8	0.5	0.4	0.9	1.3	1.2	1.0	1.1	0.1	1.1	0.4
Hypothyroidism (self reported)	0.3	0.7	1.3	-1.1	0.9	0.8	0.1	1.1	0.8	1.0	1.0	1.1	1.0	0.7	0.7	0.8	1.0	0.6	0.8	1.2	0.9	0.6	0.5	0.7	1.0	0.2	0.7
Lung FEV1/FVC ratio	0.3	1.7	3.4	-0.6	-1.6	-1.8	-1.5	-1.4	-0.7	-0.8	-1.1	-1.2	-1.1	-1.8	-1.2	-1.7	-1.7	-0.5	-1.6	-1.2	-1.1	-0.3	-1.3	-0.5	-1.9	-1.4	-1.5
Relative age of first facial hair	0.3	0.7	2.5	0.9	1.1	0.5	-1.0	0.7	0.5	0.7	0.5	1.6	0.1	0.8	0.9	0.8	1.2	0.6	0.9	0.7	0.2	0.7	0.3	0.7	1.0	0.3	1.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.7	-1.3	-0.7	-0.6	-0.6	-0.2	-0.1	0.0	-0.1	-0.1	-0.7	-0.6	-0.7	-0.6	-0.7	-0.6	-0.6	-0.0	-0.2	-0.7	-0.7	-0.4	-0.4	-1.0	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.1	-0.8	-0.7	-0.7	-0.8	-0.4	-0.3	-0.4	-0.3	-1.0	-0.9	-0.8	-0.7	-0.8	-0.1	-0.8	-0.7	-0.4	-0.4	-0.2	-0.9	-0.5	-0.4	-0.9	-0.4
Waist circumference	0.3	1.1	3.3	-1.7	-1.3	-1.0	0.6	-1.0	-0.5	-0.4	-0.7	-1.8	-0.0	-1.2	-1.2	-1.1	-1.5	-0.7	-1.1	-0.7	-0.7	-1.5	-0.3	-0.9	-1.1	-0.3	-1.5
Arm fat percentage (right)	0.3	1.2	4.2	-2.0	-1.3	-0.7	1.3	-1.0	-0.3	-0.2	-0.5	-2.1	0.4	-1.2	-1.0	-1.1	-1.8	-0.4	-1.0	-0.7	-0.3	-1.2	0.3	-0.7	-1.3	0.2	-1.6
Trunk fat-free mass	0.3	1.5	5.0	0.7	1.6	0.4	0.6	0.9	1.3	1.6	1.2	2.2	1.4	1.2	1.5	1.3	1.0	1.7	1.3	1.2	0.4	0.3	1.1	1.4	1.1	0.3	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	2.3	1.0	0.5	-0.4	-1.5	0.1	0.1	0.2	0.1	1.3	0.1	0.5	0.3	0.5	0.4	0.2	0.3	0.1	-0.2	0.6	0.1	0.8	-0.0	-0.2	0.4
High blood pressure (siblings)	0.3	0.5	2.5	0.7	-0.5	-0.7	0.5	-0.9	-0.4	-0.6	-0.5	-1.2	-0.0	-0.6	-0.3	-0.6	-0.9	-0.0	-0.6	-0.7	-0.7	-1.6	-0.1	-1.1	-0.3	-0.1	-0.9
Leg fat percentage (right)	0.3	1.1	4.8	-1.6	-1.2	-1.0	1.2	-1.1	-0.1	0.2	-0.5	-1.4	0.5	-1.1	-0.9	-1.0	-2.2	-0.0	-1.0	-0.7	-0.5	-1.7	0.3	-0.7	-1.2	0.3	-1.6
Arm fat-free mass (right)	0.3	1.4	4.3	0.5	1.6	0.4	0.4	0.9	1.3	1.6	1.2	2.1	1.1	1.2	1.5	1.3	0.9	1.8	1.2	1.3	0.4	0.3	1.1	1.4	1.2	0.3	0.9
Shortness of breath walking on level ground	0.3	0.3	1.3	0.7	-0.1	-0.1	-1.1	-0.3	-0.7	-0.2	-0.6	1.1	-0.8	-0.3	-0.4	-0.3	0.6	-0.9	-0.2	-0.3	-0.6	0.3	-0.6	-0.5	0.0	-0.5	-0.1
Medication: Blood pressure	0.3	0.5	5.0	-1.6	-0.8	-0.4	0.2	-0.0	0.3	-0.3	0.4	-2.2	-0.9	-0.7	-0.5	-0.6	-0.2	-0.3	-0.5	-0.1	0.5	0.2	0.0	-0.0	-0.5	0.2	-0.3
Heart disease (mother)	0.3	0.4	1.0	-0.9	0.3	0.7	-0.1	1.0	0.7	0.6	0.7	1.0	-0.1	0.4	0.2	0.5	0.6	-0.0	0.4	0.8	1.0	0.5	0.1	0.7	0.5	0.0	0.6
Arm predicted mass (right)	0.3	1.4	4.6	0.5	1.6	0.4	0.4	1.0	1.3	1.6	1.2	2.1	1.1	1.3	1.5	1.4	0.9	1.7	1.3	1.3	0.4	0.4	1.2	1.5	1.1	0.4	0.9
Had major operations	0.3	0.3	4.0	-2.0	-0.3	0.3	-0.7	0.3	0.1	0.5	0.2	0.6	-0.5	-0.3	-0.3	-0.2	0.5	-0.5	-0.1	0.2	0.3	-0.4	-0.7	-0.5	0.6	-0.6	0.2
Supplements: Vitamin C	0.3	0.3	1.4	0.3	0.7	0.3	0.4	0.6	0.5	0.5	0.6	0.5	0.4	0.6	0.6	0.6	1.2	0.6	0.6	0.7	0.3	0.9	0.3	0.6	0.6	0.3	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.9	0.6	-0.5	-0.8	-0.7	-0.6	-0.4	-0.5	-0.6	0.0	-1.4	-0.4	-0.5	-0.4	-0.2	-0.4	-0.5	-0.6	-0.8	-0.8	-0.5	-1.1	-0.0	-0.7	-0.6
Arm fat percentage (left)	0.3	1.3	3.6	-1.5	-1.3	-1.0	1.0	-1.2	-0.6	-0.3	-0.7	-1.9	0.1	-1.3	-1.1	-1.2	-1.9	-0.6	-1.2	-0.9	-0.8	-1.5	-0.0	-0.8	-1.4	-0.2	-1.8
Breast cancer (self-reported)	0.3	0.4	1.1	-1.0	-0.9	-0.3	-0.8	-0.4	-0.5	-0.5	-0.2	-0.8	-0.3	-0.8	-0.8	-0.8	-0.2	-0.6	-0.7	-0.4	-0.1	-0.5	-0.7	-0.8	-0.5	-0.3	-0.6
Medication: Aspirin	0.3	0.4	2.4	0.3	0.6	0.3	0.5	0.4	0.6	0.4	0.3	0.1	0.4	0.4	0.6	0.5	0.8	0.6	0.6	0.5	0.4	1.5	0.9	1.1	0.0	0.7	0.3
Leg fat percentage (left)	0.3	1.1	4.1	-1.7	-1.2	-1.0	1.4	-1.0	-0.1	0.2	-0.4	-1.8	0.4	-1.1	-0.9	-1.0	-2.0	-0.1	-0.9	-0.6	-0.4	-1.6	0.3	-0.6	-1.2	0.4	-1.5
Average weekly beer plus cider intake	0.3	0.5	2.7	0.5	-0.3	-0.6	-0.8	-0.5	-0.7	-0.5	-0.7	0.4	-1.0	-0.6	-0.5	-0.6	-0.0	-0.7	-0.6	-0.5	-0.9	0.0	-1.1	-0.6	-0.3	-1.6	-0.5
Ever depressed for a whole week	0.3	0.4	1.1	0.1	-0.7	-0.6	-0.1	-0.5	-0.8	-0.3	-0.6	0.3	-0.9	-0.6	-0.8	-0.6	-0.6	-0.9	-0.7	-0.6	-0.4	-0.7	-0.7	-1.0	-0.3	-0.5	-0.6
Arm predicted mass (left)	0.3	1.5	3.8	-0.2	1.4	0.6	1.0	1.0	1.6	1.7	1.4	1.5	1.5	1.1	1.5	1.3	0.8	1.9	1.2	1.4	0.8	0.3	1.5	1.4	1.1	0.7	0.8
HbA1C	0.2	0.2	0.6	-0.1	0.5	0.5	0.2	0.3	0.6	0.6	0.6	0.4	0.6	0.4	0.5	0.5	0.6	0.4	0.5	0.4	0.2	0.1	0.5	0.6	0.4	0.8	0.5
Blood White Count	0.2	1.6	3.7	0.1	1.2	1.2	1.1	1.5	0.7	1.1	0.9	1.3	1.6	1.5	1.1	1.5	0.0	0.9	1.2	1.3	1.7	1.1	1.7	1.5	0.8	1.9	1.2
BMI	0.2	1.3	4.0	-1.5	0.6	0.3	1.6	0.7	1.4	1.9	1.1	0.9	2.0	0.7	0.9	0.7	-0.7	1.5	0.8	1.0	1.0	-0.2	1.7	1.2	0.3	1.4	0.1
Hearing difficulty/problems: Yes	0.2	0.3	3.3	1.8	0.8	-0.0	-0.3	-0.0	-0.2	0.1	-0.1	1.1	0.5	0.6	0.6	0.5	0.8	0.2	0.4	0.0	-0.4	0.4	0.1	-0.0	0.6	0.2	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.4	0.3	-0.2	-0.5	-0.0	-0.4	-0.7	-0.7	-0.3	-0.5	-1.2	-0.3	-0.4	-0.3	-0.3	-0.8	-0.4	-0.4	-0.5	0.5	-0.4	-0.2	-0.7	-0.5	-0.6
Medication: Metformin	0.2	0.3	0.8	-0.2	0.5	-0.2	0.9	0.2	0.5	0.9	0.6	0.6	0.3	0.3	0.5	0.4	-0.1	0.7	0.4	0.4	0.2	0.1	0.9	0.6	-0.0	0.7	-0.2
Leg fat-free mass (left)	0.2	1.0	2.1	-0.1	1.3	0.3	0.7	0.8	1.1	1.4	1.0	1.4	1.3	1.0	1.2	1.1	0.6	1.4	1.0	1.1	0.4	0.4	1.1	1.4	0.7	0.3	0.5
Average weekly fortified wine intake	0.2	0.2	2.2	1.0	0.5	0.3	-0.2	0.2	0.1	0.7	0.3	1.5	0.2	0.5	0.4	0.4	0.1	0.4	0.3	0.3	-0.1	0.4	0.1	0.6	0.1	-0.2	0.1
Fed-up feelings	0.2	0.4	1.3	0.0	0.8	0.6	-0.2	0.8	0.4	0.3	0.5	0.4	0.5	0.6	0.7	0.7	0.7	0.4	0.6	0.6	0.8	0.1	0.6	0.2	1.1	0.5	0.9
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.0	-0.6	-0.7	-0.0	0.7	-0.3	-0.2	-0.3	-0.3	-1.0	-0.1	-0.6	-0.5	-0.5	-0.1	-0.4	-0.5	-0.4	-0.2	-0.1	-0.4	-0.3	-0.4	-0.1	-0.2
Multivitamins +/- minerals	0.2	0.3	1.2	0.9	0.5	0.3	-1.1	0.3	0.0	0.1	0.3	0.6	0.8	0.7	0.4	0.6	-0.5	0.3	0.5	0.2	0.3	-0.3	0.5	0.8	0.0	0.9	0.6
Sitting height	0.2	1.4	3.6	0.5	-0.8	-1.2	-1.8	-1.1	-1.5	-1.3	-1.1	0.1	-1.2	-1.2	-1.1	-1.1	-0.9	-1.3	-1.2	-1.0	-1.4	-1.0	-1.6	-0.7	-1.1	-1.9	-1.0
Leg predicted mass (left)	0.2	1.0	2.3	-0.1	1.4	0.3	0.7	0.8	1.1	1.4	1.0	1.5	1.3	1.0	1.3	1.1	0.6	1.4	1.1	1.1	0.4	0.4	1.2	1.5	0.7	0.4	0.5
Nervous feelings	0.2	0.4	1.3	-1.0	0.6	0.6	-0.6	0.7	0.4	0.7	0.4	1.1	0.2	0.6	0.5	0.6	-0.4	0.4	0.5	0.7	0.8	-0.3	0.6	0.1	1.0	1.0	0.8
Hearing difficulty/problems with background noise	0.2	0.3	2.1	1.4	0.7	0.0	-0.4	0.2	-0.1	0.0	-0.0	0.8	0.3	0.7	0.5	0.6	0.6	0.2	0.5	0.1	-0.1	0.2	0.3	0.1	0.6	0.5	0.6
Financial difficulties in last 2 years	0.2	0.3	2.0	1.4	-0.0	-0.4	-0.7	-0.4	-0.6	-0.2	-0.5	0.2	-1.2	-0.2	-0.1	-0.2	0.7	-0.5	-0.2	-0.4	-0.8	-0.2	-0.5	-0.4	0.2	-0.4	0.2
Mouth/teeth dental problems	0.2	0.3	0.9	0.3	0.6	0.4	0.9	0.4	0.4	-0.0	0.5	-0.7	0.9	0.6	0.7	0.6	-0.0	0.7	0.6	0.3	0.5	0.4	0.8	0.2	0.5	0.9	0.4
Medication: Ramipril	0.2	0.2	0.6	0.1	0.4	-0.1	0.3	0.4	0.6	0.5	0.6	0.4	0.3	0.4	0.5	0.4	0.8	0.5	0.4	0.5	0.5	0.5	0.7	0.4	0.3	0.4	0.2
Hip circumference	0.2	0.7	2.1	-1.3	-0.9	-0.8	1.5	-0.7	-0.2	0.1	-0.3	-1.3	0.4	-0.8	-0.7	-0.7	-1.2	-0.1	-0.7	-0.4	-0.4	-1.1	0.2	-0.1	-1.0	-0.1	-1.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.8	-1.3	-0.6	0.2	1.0	-0.1	-0.0	0.1	-0.1	-0.4	0.4	-0.4	-0.5	-0.4	-0.4	-0.2	-0.3	-0.1	0.3	-0.8	-0.0	-0.9	0.1	0.0	-0.4
Medication: Cholesterol lowering	0.2	0.2	2.6	-1.6	-0.0	-0.1	0.5	0.4	0.5	0.3	0.4	-0.7	0.2	-0.0	0.1	0.1	0.1	0.2	0.2	0.4	0.7	0.2	0.6	0.3	0.0	0.7	0.0
Lung cancer (father)	0.2	0.3	1.2	-0.4	-0.5	-0.6	-0.8	-0.5	-0.3	-0.1	-0.4	0.1	-1.1	-0.6	-0.5	-0.6	-0.4	-0.5	-0.5	-0.4	-0.5	-0.3	-0.9	-0.5	-0.2	-0.7	-0.2
Trunk predicted mass	0.2	1.3	5.0	0.8	1.5	0.4	0.5	0.8	1.2	1.5	1.1	2.2	1.3	1.2	1.4	1.3	0.9	1.7	1.2	1.2	0.3	0.2	1.0	1.3	1.1	0.2	0.8
Hair/balding pattern: Pattern 4	0.2	0.5	4.7	-2.2	-0.2	0.8	1.3	0.7	0.6	0.6	0.7	-0.2	1.0	0.1	-0.0	0.2	0.3	0.2	0.1	0.7	1.1	0.3	0.4	0.5	0.1	0.2	0.1
Headache pain in last month	0.2	0.3	1.6	-0.3	-0.2	-0.3	-1.3	-0.1	-0.5	-0.2	-0.4	0.4	-0.9	-0.3	-0.4	-0.3	0.4	-0.8	-0.2	-0.2	-0.4	0.7	-0.8	-0.0	-0.2	-0.7	-0.1
Medication: Amlodipine	0.2	0.2	1.5	-1.2	-0.4	-0.2	0.5	-0.1	-0.0	-0.1	0.0	-0.6	-0.8	-0.5	-0.4	-0.4	-0.1	-0.4	-0.4	-0.1	0.1	0.8	-0.4	0.1	-0.4	-0.4	-0.2
Birth weight	0.2	0.4	1.4	-0.8	-0.7	-0.4	-0.9	-0.3	-0.4	-0.5	-0.4	-0.3	-0.5	-0.6	-0.8	-0.6	-1.2	-0.7	-0.7	-0.2	-0.3	-0.7	-1.1	-0.4	-0.3	-1.1	-0.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.7	0.2	0.5	0.6	0.0	0.4	0.4	0.5	0.3	0.6	0.2	0.5	0.6	0.5	-0.0	0.6	0.5	0.4	0.5	0.2	0.8	0.4	0.4	0.8	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	2.9	-0.1	-0.2	-0.2	-0.5	-0.2	-0.2	-0.1	-0.2	-0.2	0.3	-0.1	-0.0	-0.1	-1.7	0.1	-0.4	-0.2	0.3	-0.2	0.6	0.3	-0.9	0.4	-0.6
Eye problems/disorders: None of the above	0.2	0.2	1.3	-0.6	-0.6	-0.1	0.1	-0.4	-0.2	-0.0	-0.2	-0.2	0.0	-0.4	-0.4	-0.4	-1.1	0.1	-0.5	-0.3	-0.2	-0.6	0.1	0.2	-0.7	-0.1	-0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.2	0.2	-0.3	-0.5	-1.1	-0.3	-0.1	-0.2	-0.2	0.6	-0.9	-0.4	-0.3	-0.4	0.1	-0.2	-0.3	-0.2	-0.5	0.0	-0.7	-0.0	-0.5	-1.1	-0.4
Whole body fat mass	0.2	1.0	3.6	-1.7	-1.1	-1.0	1.3	-1.0	-0.2	0.1	-0.4	-1.6	0.5	-1.1	-0.8	-1.0	-1.9	-0.1	-0.9	-0.6	-0.5	-1.3	0.3	-0.4	-1.3	0.2	-1.6
Leg fat mass (right)	0.2	0.6	2.4	-1.5	-0.6	-0.7	1.3	-0.6	0.3	0.7	0.0	-0.7	0.9	-0.6	-0.3	-0.5	-1.5	0.5	-0.5	-0.1	-0.2	-1.1	0.6	0.0	-0.8	0.3	-1.1
Comparative height size at age 10	0.2	1.3	2.4	0.7	-0.9	-1.4	-1.6	-1.1	-1.3	-1.4	-1.1	-0.7	-1.0	-1.1	-1.1	-1.0	-0.7	-1.0	-1.2	-1.1	-1.3	-1.4	-1.3	-1.4	-0.7	-1.4	-1.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.5	0.6	-0.2	-0.4	0.8	-0.3	0.2	-0.4	0.1	-1.2	0.2	-0.1	0.0	-0.1	-0.1	0.2	-0.1	-0.2	-0.1	-1.1	0.1	-0.6	0.4	0.5	0.3
Illnesses of father: Heart disease	0.2	0.3	1.6	-0.2	-0.3	-0.2	0.5	-0.1	-0.4	-0.6	-0.4	-0.7	1.0	-0.0	-0.3	-0.0	-1.1	-0.6	-0.1	-0.4	0.4	-0.1	0.6	-0.3	-0.4	1.3	0.0
Whole body fat-free mass	0.2	1.2	3.8	0.4	1.5	0.3	0.6	0.9	1.2	1.5	1.1	1.9	1.2	1.1	1.4	1.2	0.8	1.6	1.2	1.2	0.4	0.3	1.1	1.4	0.9	0.3	0.7
Leg fat-free mass (right)	0.2	1.0	2.3	-0.2	1.3	0.3	0.8	0.9	1.1	1.3	1.0	1.3	1.3	1.0	1.3	1.1	0.8	1.4	1.1	1.2	0.5	0.6	1.1	1.5	0.7	0.3	0.6
Long-standing illness, disability or infirmity	0.2	0.3	1.0	-0.3	0.4	0.2	0.6	0.5	0.7	0.7	0.7	0.0	0.2	0.5	0.5	0.5	0.2	0.8	0.5	0.6	0.7	0.5	1.0	0.6	0.3	1.0	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.6	1.2	0.1	-0.2	-0.0	-0.5	-0.3	0.3	-0.4	1.1	-0.0	-0.1	0.0	-0.1	0.1	0.0	-0.0	-0.3	-0.8	-0.8	-0.1	-0.2	-0.1	-0.3	-0.4
Whole body water mass	0.2	1.3	4.2	0.4	1.6	0.4	0.5	0.9	1.2	1.6	1.1	2.0	1.2	1.2	1.5	1.3	1.0	1.7	1.2	1.3	0.4	0.4	1.1	1.5	1.0	0.2	0.7
Leg predicted mass (right)	0.2	1.2	2.5	-0.3	1.4	0.4	0.8	0.9	1.2	1.4	1.1	1.4	1.4	1.1	1.3	1.2	0.8	1.5	1.1	1.2	0.6	0.7	1.2	1.6	0.8	0.4	0.6
Miserableness	0.2	0.4	1.0	-0.6	0.6	0.4	-0.7	0.8	0.8	0.8	0.6	1.0	0.4	0.4	0.6	0.5	0.7	0.6	0.5	0.8	0.8	0.4	0.4	0.3	1.0	0.5	0.8
Ever taken oral contraceptive pill	0.2	0.2	1.4	0.6	-0.2	-0.3	-0.5	-0.3	-0.3	-0.1	-0.2	0.5	-1.2	-0.3	-0.3	-0.3	0.1	-0.4	-0.3	-0.3	-0.6	-0.1	-0.5	0.1	-0.3	-0.7	-0.2
Commuting to job workplace: Public transport	0.2	0.3	2.0	0.9	0.5	0.1	-0.8	0.2	0.1	-0.3	0.1	0.4	0.1	0.5	0.4	0.4	0.6	0.2	0.3	0.1	0.0	1.4	0.1	1.0	-0.4	-0.0	0.2
Medication: Lisinopril	0.2	0.3	2.2	-0.9	-0.6	-0.5	0.3	-0.3	-0.0	-0.3	0.0	-1.5	-0.0	-0.5	-0.4	-0.5	-0.4	-0.1	-0.5	-0.3	-0.2	0.0	-0.3	0.2	-0.7	-0.6	-0.4
Illnesses of father: High blood pressure	0.2	0.3	1.6	1.3	-0.2	-0.3	-0.4	-0.3	-0.5	-1.2	-0.7	-1.2	-0.3	-0.1	-0.2	-0.1	-0.4	-0.5	-0.2	-0.6	-0.3	-0.0	-0.2	-0.4	-0.1	0.1	0.1
Neuroticism (Nagel 2018)	0.1	0.2	1.1	0.1	0.4	0.5	-0.1	0.4	0.2	0.2	0.1	0.2	0.3	0.4	0.4	0.3	0.3	0.4	0.4	0.2	0.4	-0.3	0.5	-0.5	1.0	0.8	0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.4	-0.1	-0.3	-0.3	0.3	-0.1	0.2	0.1	0.2	-0.2	0.3	-0.0	-0.2	-0.1	0.4	0.1	-0.0	-0.0	-0.0	-0.6	0.2	-0.4	0.1	-0.0	-0.3
Crohns Disease (2017)	0.1	0.2	0.7	0.8	0.4	0.5	-0.0	0.4	0.4	0.2	0.2	0.2	0.3	0.4	0.5	0.4	0.4	0.3	0.4	0.3	0.3	0.5	0.2	0.9	0.2	0.4	0.8
LDL Cholesterol	0.1	0.2	1.8	0.6	-0.0	-0.3	-1.3	-0.3	-0.2	-0.2	-0.1	0.4	-0.5	-0.1	0.0	-0.2	-0.1	-0.0	-0.2	-0.2	-0.5	-0.4	-0.4	0.2	-0.5	-0.7	-0.3
Neuroticism (2016)	0.1	0.2	1.1	-0.3	-0.0	0.4	-0.2	0.2	0.3	-0.4	0.4	-1.1	0.3	0.3	0.1	0.3	0.7	0.3	0.3	0.1	0.1	0.3	0.2	-0.2	0.5	0.5	0.3
Blood Eosinophil Count	0.1	0.6	1.6	0.5	-0.5	-0.9	-1.0	-0.7	-1.2	-1.2	-0.9	-1.0	-0.1	-0.4	-0.7	-0.4	-1.0	-0.8	-0.7	-0.8	-0.7	-0.9	-0.2	-0.5	-0.9	-0.3	-0.9
Heel T-Score	0.1	1.1	7.6	-2.8	-1.3	-0.2	-0.7	-0.6	-0.1	-0.0	0.3	-0.9	-0.2	-1.2	-1.1	-1.2	-0.8	-0.8	-1.0	-0.3	-0.4	-1.7	-1.1	-1.3	-0.5	-1.2	-1.0
Tanning	0.1	0.8	1.7	-0.4	1.1	0.6	0.0	1.1	0.8	1.1	1.0	1.3	0.2	1.0	1.1	1.1	1.0	0.9	1.0	1.1	1.0	0.3	1.1	0.6	1.2	0.4	0.7
Angina	0.1	0.1	0.4	0.4	-0.3	-0.5	-0.6	-0.4	-0.3	-0.4	-0.3	-0.6	-0.3	-0.4	-0.1	-0.3	0.3	-0.2	-0.3	-0.4	-0.1	-0.5	0.1	-0.6	-0.3	0.2	-0.4
Vitamin and mineral supplements	0.1	0.2	2.3	-1.5	-0.4	0.1	0.6	0.1	0.3	0.5	0.2	0.1	-0.3	-0.3	-0.2	-0.3	0.3	0.0	-0.2	0.3	0.2	-0.2	-0.1	-0.5	0.3	-0.5	-0.3
Severe depression (siblings)	0.1	0.1	1.3	1.1	0.1	-0.2	-0.9	-0.2	-0.1	-0.1	-0.1	0.5	-0.0	0.2	0.1	0.1	-0.4	0.1	0.1	-0.2	-0.3	-0.0	-0.0	0.3	-0.3	0.4	0.0
Age when periods started (menarche)	0.1	0.3	1.9	0.7	0.3	0.3	1.4	0.2	0.3	0.3	0.4	-0.3	1.1	0.5	0.4	0.4	0.2	0.6	0.4	0.2	0.4	0.2	0.8	0.1	0.4	0.6	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.8	-1.3	-0.2	0.7	0.1	0.6	0.2	0.1	0.4	-0.2	-0.5	0.0	-0.3	0.0	0.8	-0.6	0.1	0.5	0.6	0.8	-0.5	0.1	0.5	-0.1	0.6
Supplements: Glucosamine	0.1	0.1	0.8	-0.3	-0.1	-0.3	-0.3	0.1	0.2	0.0	0.3	-0.9	0.1	0.0	-0.0	-0.0	-0.1	0.0	-0.0	0.1	0.1	-0.7	0.0	-0.1	0.2	0.3	0.1
Alcohol usually taken with meals	0.1	0.2	0.8	-0.0	-0.5	-0.3	-0.5	-0.4	-0.4	-0.7	-0.5	-0.9	0.1	-0.5	-0.6	-0.4	-0.3	-0.6	-0.4	-0.4	-0.2	0.1	-0.5	-0.3	-0.5	-0.1	-0.3
Weight	0.1	0.3	1.1	-0.8	-0.4	-0.8	0.7	-0.6	0.1	0.4	-0.1	-0.4	0.6	-0.6	-0.3	-0.5	-1.0	0.3	-0.5	-0.2	-0.5	-1.0	0.3	0.0	-0.7	-0.2	-1.0
Worrier / anxious feelings	0.1	0.2	1.3	1.1	0.2	-0.4	-0.7	-0.4	-0.3	-0.6	-0.5	-0.7	-0.7	-0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.5	-0.7	-0.2	-0.2	-0.0	-0.2	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	4.0	2.0	0.8	-0.1	0.5	0.1	0.1	-0.4	0.1	-0.3	0.6	0.7	0.8	0.6	0.6	0.7	0.7	0.0	-0.1	0.8	0.5	0.3	0.5	0.8	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.7	1.3	0.8	0.2	0.8	0.4	0.2	-0.1	0.3	-0.3	0.5	0.6	0.8	0.6	1.0	0.5	0.7	0.3	0.1	0.9	0.3	0.3	0.8	0.7	0.9
Arm fat mass (right)	0.1	0.5	2.6	-1.6	-0.6	-0.4	1.4	-0.5	0.3	0.5	0.0	-1.0	0.8	-0.6	-0.3	-0.5	-1.1	0.3	-0.4	-0.1	-0.1	-0.8	0.7	0.0	-0.8	0.4	-1.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.6	-0.4	-0.5	-0.5	-0.2	-0.2	-0.3	-0.4	-0.2	-0.8	-0.1	-0.5	-0.4	-0.4	-0.3	-0.5	-0.4	-0.3	0.1	-0.2	-0.5	-0.4	-0.2	0.2	0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.7	-0.7	0.1	0.5	-0.8	0.4	0.0	0.3	0.3	0.6	-0.2	0.1	0.0	0.2	0.3	-0.1	0.1	0.3	0.5	0.5	-0.0	0.9	-0.2	0.1	0.5
Glaucoma (self-reported)	0.1	0.1	0.7	0.6	0.4	0.3	-0.1	0.3	0.1	0.2	0.0	0.8	0.6	0.3	0.4	0.3	0.7	0.2	0.3	0.2	0.3	0.2	0.4	0.1	0.4	0.4	0.3
Angina (self-reported)	0.1	0.1	0.7	0.5	0.3	-0.0	-0.3	0.1	0.1	0.1	0.1	-0.1	0.1	0.2	0.4	0.2	0.8	0.3	0.3	0.1	0.2	-0.2	0.6	-0.2	0.3	0.5	0.0
Migraine (self-reported)	0.1	0.1	0.4	0.3	-0.2	-0.6	0.5	-0.4	0.0	0.3	-0.1	0.2	0.0	-0.1	-0.1	-0.2	-0.2	0.3	-0.1	-0.2	-0.5	0.5	0.2	0.2	-0.5	0.2	-0.5
Medication: Allopurinol	0.1	0.1	1.3	-0.6	0.1	-0.0	-1.1	0.3	0.1	0.0	0.3	0.4	-0.5	0.1	-0.0	0.1	0.7	-0.1	0.1	0.3	0.1	-0.3	-0.3	0.1	0.2	-0.4	0.2
Medication: Seretide 50 evohaler	0.1	0.2	1.0	0.1	-0.1	-0.2	-0.8	-0.1	-0.1	-0.3	-0.0	0.7	-0.0	-0.1	-0.3	-0.1	0.3	-0.2	-0.1	-0.1	-0.4	0.4	-0.8	-0.4	0.1	-1.0	-0.2
Alcohol intake frequency.	0.1	0.3	1.5	0.2	0.8	0.9	-0.8	0.5	-0.1	0.2	0.2	1.2	0.5	0.7	0.6	0.6	0.5	0.2	0.5	0.4	0.2	0.6	0.4	0.5	0.6	0.5	0.7
Overall health rating	0.1	0.1	0.4	-0.1	-0.5	-0.5	0.3	-0.3	-0.4	-0.5	-0.6	-0.6	-0.3	-0.4	-0.5	-0.3	-0.4	-0.6	-0.4	-0.4	-0.1	-0.2	-0.1	-0.5	-0.3	0.3	-0.2
Age at last live birth	0.1	0.1	0.4	0.3	0.1	-0.1	0.5	0.0	-0.1	0.2	-0.1	0.6	-0.4	0.1	0.0	0.1	0.6	-0.1	0.1	0.0	-0.2	-0.7	-0.1	-0.5	0.5	-0.1	0.2
Leg pain on walking	0.1	0.2	1.3	1.0	0.1	-0.5	-1.1	-0.2	-0.5	-0.3	-0.3	0.8	-0.4	0.0	-0.2	-0.1	0.1	-0.6	-0.1	-0.3	-0.4	0.1	-0.2	-0.2	-0.1	-0.2	-0.2
Medication: Aspirin	0.1	0.1	0.8	0.9	-0.0	-0.3	0.4	-0.3	0.1	-0.1	-0.2	-0.4	-0.1	-0.2	0.0	-0.2	0.4	0.2	-0.0	-0.1	-0.4	0.7	0.3	0.3	-0.4	0.0	-0.4
Average weekly red wine intake	0.1	0.2	1.3	0.4	0.2	0.2	0.5	0.3	0.4	-0.3	0.1	-0.9	0.5	0.5	0.3	0.5	-0.0	0.2	0.5	0.2	0.5	0.1	0.7	0.2	0.3	1.1	0.5
Loneliness, isolation	0.1	0.1	0.7	0.4	0.2	-0.1	-0.2	0.1	-0.2	-0.1	-0.0	0.2	0.1	0.1	0.1	0.1	0.6	-0.2	0.2	0.0	-0.1	-0.5	-0.1	-0.8	0.8	0.1	0.2
Ever had bowel cancer screening	0.1	0.1	0.5	-0.7	0.3	-0.1	0.0	0.3	0.5	0.2	0.4	-0.5	0.4	0.3	0.4	0.3	-0.2	0.6	0.2	0.4	0.5	0.0	0.5	0.3	0.2	0.2	0.1
Qualifications: nursing, teaching	0.1	0.2	0.7	0.0	0.2	0.4	-0.1	0.5	0.1	-0.2	0.4	-0.6	0.4	0.5	0.2	0.5	0.3	0.2	0.3	0.4	0.6	0.3	0.4	0.4	0.5	0.8	0.9
Osteoarthritis (self-reported)	0.1	0.2	0.5	-0.1	0.5	-0.0	0.2	0.4	0.4	0.5	0.3	0.2	0.2	0.5	0.5	0.5	-0.7	0.3	0.3	0.4	0.6	0.0	0.7	0.6	-0.1	0.4	0.1
Medication: Gliclazide	0.1	0.1	0.3	0.6	0.1	-0.2	-0.1	-0.3	-0.3	-0.2	-0.3	-0.1	0.0	0.1	-0.0	0.1	-0.3	-0.1	0.0	-0.2	-0.5	0.3	0.1	0.1	-0.4	-0.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.3	0.1	0.1	0.1	1.2	0.1	0.1	-0.0	0.4	-0.8	0.2	0.1	0.3	0.2	0.6	0.5	0.3	0.1	0.5	0.4	0.6	-0.4	0.5	1.0	0.3
Arm fat mass (left)	0.1	0.5	2.2	-1.5	-0.6	-0.5	1.1	-0.5	0.2	0.5	-0.0	-0.8	0.7	-0.6	-0.3	-0.5	-1.1	0.2	-0.5	-0.1	-0.3	-1.0	0.5	-0.1	-0.7	0.2	-1.1
Wears glasses or contact lenses	0.1	0.1	0.7	-0.3	-0.5	-0.4	-0.2	-0.4	-0.1	-0.2	-0.3	-0.3	-0.2	-0.4	-0.5	-0.4	-0.2	-0.4	-0.3	-0.3	-0.2	-0.4	-0.4	-0.8	0.1	-0.2	-0.2
Hearing aid user	0.1	0.1	0.5	-0.7	-0.4	0.1	0.0	-0.3	-0.4	-0.1	-0.4	-0.1	-0.0	-0.5	-0.4	-0.5	-0.5	-0.2	-0.5	-0.3	-0.1	-0.5	-0.2	-0.7	-0.1	-0.2	-0.4
High cholesterol (Self-reported)	0.1	0.2	1.5	-1.2	-0.5	-0.5	-0.1	-0.2	-0.1	-0.1	-0.0	-1.1	-0.4	-0.6	-0.4	-0.6	-0.1	-0.2	-0.5	-0.1	-0.0	0.1	-0.1	-0.0	-0.6	-0.2	-0.6
Medication: Atorvastatin	0.1	0.1	0.8	0.9	0.4	-0.3	0.3	-0.0	-0.2	-0.5	-0.1	-0.1	0.2	0.5	0.3	0.4	-0.2	0.0	0.3	-0.1	-0.1	0.8	0.3	0.3	-0.2	0.1	-0.0
Alcohol drinker status: Never	0.1	0.2	1.3	1.1	0.6	-0.1	-0.7	0.1	-0.4	-0.2	-0.2	0.6	-0.2	0.5	0.4	0.4	0.1	0.1	0.3	-0.0	-0.4	-0.2	-0.0	-0.0	0.4	0.1	0.3
Basal metabolic rate	0.1	0.8	2.0	-0.0	1.1	0.2	0.7	0.6	1.0	1.4	0.9	1.4	1.1	0.8	1.1	0.9	0.4	1.4	0.8	0.9	0.3	0.0	1.0	1.2	0.6	0.2	0.3
Age started oral contraceptive pill	0.1	0.1	0.8	0.5	-0.3	-0.3	-0.2	-0.3	-0.3	-0.4	-0.2	-0.9	0.1	-0.2	-0.1	-0.3	-0.4	-0.1	-0.4	-0.4	-0.2	-0.2	-0.1	-0.1	-0.4	-0.2	-0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.9	0.4	0.3	-0.1	-0.7	-0.0	-0.3	0.0	-0.2	0.5	-0.1	0.2	0.2	0.2	-0.9	-0.2	-0.1	0.0	-0.2	-0.6	-0.0	0.2	-0.2	-0.4	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	1.1	0.5	0.3	0.1	-0.2	0.1	-0.3	-0.6	-0.2	0.2	-0.1	0.4	0.0	0.3	0.6	-0.4	0.3	-0.1	-0.1	-0.3	0.1	-1.1	0.9	-0.1	0.1
Leg fat mass (left)	0.1	0.6	2.3	-1.5	-0.6	-0.7	1.3	-0.5	0.3	0.6	0.0	-1.0	0.8	-0.6	-0.3	-0.5	-1.4	0.5	-0.4	-0.1	-0.2	-1.1	0.6	0.1	-0.7	0.4	-1.0
Triglycerides	0.0	0.1	0.5	-0.4	-0.1	-0.1	0.2	0.1	0.3	0.2	0.2	0.2	-0.1	-0.1	0.0	0.0	0.0	0.3	0.1	0.2	0.3	-0.0	0.3	0.7	-0.3	0.6	0.1
Blood Platelet Count	0.0	0.2	1.1	0.4	-0.2	-0.0	-0.7	0.2	-0.3	-0.7	-0.1	-1.1	-0.4	0.2	-0.1	0.2	-0.6	-0.3	-0.0	-0.1	0.5	-0.0	0.3	0.0	-0.2	1.0	0.4
Hair Pigment	0.0	0.1	0.5	-0.7	-0.1	0.1	0.6	0.2	0.1	-0.2	-0.2	-0.7	0.3	0.1	-0.1	0.1	-0.1	-0.2	0.0	0.1	0.5	0.0	0.1	0.2	-0.1	0.3	0.2
Relative age voice broke	0.0	0.1	0.1	-0.3	0.1	-0.1	-0.1	0.2	0.3	0.2	0.2	-0.2	-0.3	-0.1	0.1	-0.1	0.4	0.3	0.1	0.3	0.2	-0.2	-0.1	0.3	0.3	0.2	0.3
Irritability	0.0	0.1	0.6	0.1	0.0	-0.1	-0.8	-0.1	-0.2	-0.3	-0.3	-0.3	-0.4	-0.1	-0.0	-0.1	-0.0	-0.2	-0.0	-0.2	-0.2	0.1	-0.1	-0.2	0.1	-0.1	-0.1
Supplements: Calcium	0.0	0.1	0.4	0.2	-0.0	-0.7	0.3	-0.1	-0.2	0.0	-0.1	0.2	0.4	-0.1	0.0	-0.1	-0.4	0.2	-0.0	-0.1	-0.1	0.1	0.2	-0.1	0.1	0.3	-0.1

Hub : Genes

ATP5G3

Models

Trait associations