TWAS hub - ATP5O

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0570	0.0260	7.0e-03	0.054	0.013	0.037	0.023	0.050	3.1e-07	9.1e-03	2.5e-05	6.9e-04	1.0e-06
2	GTEx	Brain Frontal Cortex BA9	0.3389	0.1021	1.6e-03	0.032	NA	0.006	NA	0.033	5.0e-02	NA	2.1e-01	NA	4.6e-02
3	GTEx	Cells EBV-transformed lymphocytes	0.2040	0.0760	2.8e-03	0.128	NA	0.041	NA	0.113	5.9e-05	NA	1.7e-02	NA	1.7e-04
4	GTEx	Cells Transformed fibroblasts	0.1500	0.0410	2.3e-06	0.166	NA	0.174	NA	0.177	1.7e-12	NA	4.8e-13	NA	2.7e-13
5	GTEx	Lung	0.1821	0.0449	3.2e-06	0.176	NA	0.147	NA	0.164	1.9e-13	NA	2.5e-11	NA	1.5e-12
6	GTEx	Uterus	0.2340	0.0910	8.1e-03	0.053	NA	0.059	NA	0.021	3.1e-02	NA	2.5e-02	NA	1.2e-01
7	YFS	Blood	0.0211	0.0073	4.4e-05	0.013	0.011	0.018	0.018	0.017	2.2e-05	1.1e-04	1.3e-06	1.3e-06	1.6e-06
8	TCGA	Breast Invasive Carcinoma	0.0351	0.0188	5.4e-04	0.014	0.012	0.005	NA	0.011	4.5e-04	1.3e-03	2.4e-02	NA	2.3e-03
9	TCGA	Brain Lower Grade Glioma	0.0772	0.0278	5.3e-08	0.098	0.085	0.088	NA	0.105	3.1e-11	6.1e-10	3.7e-10	NA	6.0e-12
10	TCGA	Prostate Adenocarcinoma	0.0261	0.0141	1.6e-03	0.015	0.009	0.001	NA	0.008	9.4e-03	3.4e-02	2.4e-01	NA	4.2e-02
11	TCGA	Thyroid Carcinoma	0.0570	0.0290	9.2e-04	0.027	0.018	0.006	NA	0.020	1.1e-03	6.1e-03	7.6e-02	NA	4.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Age when periods started (menarche)	4.8	11.6	20.0	4.4	1.3	2.6	4.5	1.7	3.4	3.5	4.4	3.5	4.3	1.6
Mouth/teeth dental problems: Dentures	4.0	6.8	13.2	2.5	0.1	1.9	3.1	1.6	3.6	3.1	2.3	2.8	3.4	2.3
Medication: Lansoprazole	4.0	4.6	10.3	-0.8	-0.4	-3.2	-1.7	-0.7	-2.4	-2.2	-2.2	-3.0	-1.4	-3.1
Lupus	3.9	5.9	17.1	-1.3	-0.7	-4.1	-1.6	0.4	-2.2	-2.6	-1.6	-3.4	-2.0	-3.6
Medication for hormone replacement therapy	3.5	3.9	7.6	-1.0	1.4	-2.4	-1.7	-0.9	-2.5	-2.3	-0.7	-2.4	-2.1	-2.8
Emphysema/chronic bronchitis	3.3	3.7	11.1	-1.4	0.2	-2.2	-2.2	-3.3	-1.4	-1.2	-1.7	-2.4	-1.0	-2.3
Mother’s age at death	3.3	4.1	6.3	2.3	1.9	2.4	2.5	-0.2	1.7	1.9	2.5	2.3	2.0	1.4
Gout (self-reported)	3.1	4.3	10.1	-3.0	-1.7	-2.3	-2.5	-0.7	-1.8	-1.2	-1.6	-3.2	-2.3	-0.8
Blood clot in the leg (DVT)	2.7	3.5	6.5	2.5	0.4	1.3	1.7	-1.6	2.5	2.1	2.3	1.8	2.4	0.7
Schizophrenia vs Biploar Disorder	2.6	3.4	15.4	-0.6	-2.2	-3.9	-0.9	0.1	-1.3	-1.9	-1.6	-2.9	-0.3	0.0
Ever taken oral contraceptive pill	2.6	2.9	4.3	-1.8	-1.8	-2.1	-1.7	-0.2	-1.9	-1.7	-1.3	-2.0	-1.8	-1.6
Major Depression (MDD)	2.5	3.0	7.0	-0.9	-2.6	-2.0	-1.5	-0.4	-1.7	-2.3	-2.3	-1.8	-1.5	0.0
Blood Red Count	2.4	23.3	64.2	8.0	2.7	4.6	6.2	-1.9	4.3	2.7	5.3	5.2	6.4	-0.3
Lung FEV1/FVC ratio	2.2	11.3	25.4	4.7	4.0	1.8	4.2	4.9	-1.3	-1.8	5.0	2.6	-1.1	-1.3
Had other major operations	2.2	2.7	10.0	1.9	0.9	0.2	1.6	-1.4	1.9	1.9	3.2	0.8	1.7	0.3
Heart disease (mother)	2.2	2.7	6.3	-1.8	-2.5	-1.2	-2.0	-0.7	-1.7	-1.4	-0.5	-1.7	-2.4	-0.6
Blood Platelet Count	2.1	24.3	38.0	-5.2	-2.9	-5.3	-5.9	-2.4	-5.8	-4.8	-4.3	-6.2	-5.3	-4.6
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	4.0	-1.5	1.2	-1.5	-1.6	-0.1	-2.0	-2.0	-1.4	-1.7	-1.9	-1.4
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	6.2	1.9	0.3	1.0	1.4	-1.6	2.5	1.9	1.9	1.5	2.1	0.7
Schizophrenia (2014)	2.0	4.4	13.7	-0.7	-0.6	-3.7	-1.0	0.6	-1.5	-2.0	-2.9	-2.9	-0.4	-3.0
Heart attack	2.0	2.6	12.7	-0.5	-3.6	-1.2	-0.7	0.0	-1.4	-1.3	-2.6	-0.8	-0.2	-1.5
Diastolic blood pressure, automated reading	2.0	6.1	15.3	-3.3	-2.2	-2.4	-2.9	-3.0	-0.4	0.0	-3.9	-3.5	0.0	-0.4
Loud music exposure frequency	1.9	2.1	4.2	-1.2	-0.2	-1.4	-1.7	-1.4	-2.0	-1.5	-1.5	-1.3	-0.6	-2.1
Ever had bowel cancer screening	1.9	2.2	4.4	1.6	0.7	1.2	1.9	2.1	1.6	1.2	1.1	1.6	1.6	1.2
Migraine (self-reported)	1.8	2.2	8.1	-0.6	2.6	-1.7	0.1	2.9	-1.5	-0.7	0.1	-1.2	-1.4	-0.3
Illnesses of father: Heart disease	1.8	2.6	19.0	-1.5	-4.4	-0.1	-1.4	0.1	-1.0	-0.4	-1.3	-1.0	-1.1	0.4
Heart attack/myocardial infarction (self-reported)	1.8	2.3	11.8	-0.5	-3.4	-1.2	-0.6	0.0	-1.2	-1.1	-2.5	-0.8	-0.0	-1.4
Diabetes (self-reported)	1.7	2.7	5.1	2.2	1.8	1.8	2.0	0.7	1.2	1.4	1.6	1.9	1.6	1.0
Prospective memory result	1.7	2.1	4.1	1.0	0.6	1.8	1.2	0.2	1.8	1.7	2.0	1.7	0.7	1.9
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	5.5	-0.7	-1.1	-0.8	-1.1	0.1	-2.0	-2.3	-1.9	-1.1	-1.6	-1.9
Mouth/teeth dental problems: Loose teeth	1.7	2.0	6.0	0.0	-1.1	-1.5	-1.1	-1.3	-1.4	-2.0	-0.2	-1.4	-1.2	-2.4
Qualifications: nursing, teaching	1.7	2.6	5.3	-1.7	-0.9	-1.3	-2.3	-2.1	-1.6	-1.3	-1.9	-1.5	-1.6	-1.0
Chronotype (morning person)	1.6	3.6	9.2	2.5	-1.3	0.3	3.0	2.8	1.5	1.4	2.1	1.6	2.0	0.5
Wheeze or whistling in the chest in last year	1.6	2.9	9.6	0.8	-2.6	-2.4	-0.6	-2.1	-0.9	-1.2	-1.0	-1.2	0.1	-3.1
Diabetes diagnosed by doctor	1.6	2.6	4.8	2.0	2.2	1.9	1.7	-0.3	1.2	1.4	1.6	1.9	1.8	0.7
Medication for cholesterol	1.5	2.3	7.9	1.2	-2.8	1.4	1.4	1.8	1.2	0.8	1.0	1.9	0.9	1.3
Medication: Atorvastatin	1.5	1.9	3.6	-1.1	-0.8	-0.6	-1.9	-1.9	-1.3	-1.7	-1.4	-0.8	-1.6	-1.2
Risk taking	1.5	2.2	7.2	0.2	0.2	-2.6	-0.4	-0.2	-0.8	-1.6	-0.4	-2.7	-0.7	-2.6
Coronary Artery Disease (CAD)	1.4	1.6	9.4	-1.5	-3.1	-0.1	-1.6	-1.4	-0.4	0.0	-0.8	-0.7	-0.7	0.0
Chronic bronchitis/emphysema (father)	1.4	1.7	5.5	-0.4	1.6	-1.6	-1.0	-2.3	-0.4	-0.5	0.2	-1.4	-0.0	-2.1
Medication: Ibuprofen	1.4	1.7	5.2	0.8	1.6	1.6	1.3	1.7	0.7	0.7	0.7	2.3	0.8	1.1
Medication: Levothyroxine sodium	1.3	2.1	6.1	-1.4	-0.5	-1.0	-2.1	-2.5	-1.6	-1.1	-1.0	-1.7	-1.3	-0.8
Happiness	1.3	1.5	5.6	1.2	0.4	1.4	0.9	-1.0	1.4	1.0	0.9	2.4	1.2	0.9
Pulse wave Arterial Stiffness index	1.3	1.6	3.6	-1.8	1.2	-1.4	-0.6	1.4	-0.8	-0.6	-1.9	-1.7	-0.8	0.1
Medication: Omeprazole	1.3	1.6	4.2	1.1	0.9	0.2	1.1	-0.6	2.0	1.8	0.7	1.0	2.0	0.7
Average weekly champagne plus white wine intake	1.3	1.8	5.5	-0.5	-0.9	-1.6	-0.4	2.3	-1.6	-1.7	-0.8	-0.5	-1.6	-1.4
Financial situation satisfaction	1.3	1.6	4.1	-1.5	-0.5	-1.2	-1.7	-1.6	-0.2	-0.7	-2.0	-1.7	-0.3	-0.8
Vitamin and mineral supplements	1.2	1.7	3.9	0.7	0.6	2.0	1.1	0.2	1.8	1.4	0.4	1.5	1.2	1.7
Medication: Metformin	1.2	1.6	2.7	1.6	0.8	1.4	1.6	0.0	1.2	1.3	1.3	1.4	1.6	0.8
Pulse wave reflection index	1.2	1.5	3.9	-1.6	1.1	-1.6	-1.0	0.1	-0.7	-0.8	-2.0	-1.6	-0.3	-1.0
Worry too long after embarrassment	1.2	2.0	4.5	1.1	0.6	1.3	1.4	-0.1	1.8	1.5	1.8	2.1	1.5	1.2
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	5.4	1.2	-0.4	1.3	1.2	1.3	0.3	0.6	2.3	1.6	-0.0	1.2
Waist Hip Ratio (WHR)	1.1	4.9	15.9	0.2	-1.8	-3.1	-0.8	-0.6	-2.7	-2.9	-0.5	-2.5	-1.5	-4.0
Diabetes (father)	1.1	1.4	5.8	0.9	2.4	0.1	1.2	0.4	1.2	0.9	1.4	0.8	1.4	0.1
Townsend deprivation index at recruitment	1.1	1.6	6.7	-1.4	-2.0	-0.4	-1.3	-2.6	0.1	0.3	-0.9	-1.4	-0.1	-0.3
Nervous feelings	1.1	2.0	3.7	1.0	0.9	1.6	1.5	0.3	1.6	1.9	0.9	1.5	1.9	1.7
Illnesses of mother	1.1	1.4	4.4	2.1	0.7	1.3	1.3	-0.2	0.9	0.5	0.8	1.7	1.4	-0.0
Exposure to tobacco smoke outside home	1.1	1.5	4.4	-0.4	-1.5	-1.8	-0.9	-0.9	-0.4	-1.2	-1.0	-1.5	-0.2	-2.1
Qualifications: College or University degree	1.1	3.5	10.0	-2.0	-2.1	-1.3	-1.8	1.0	-2.5	-1.9	-0.8	-1.9	-3.2	-0.7
Commuting to job workplace: Car/motor vehicle	1.1	1.2	4.2	-1.4	2.0	-0.6	-1.3	-0.6	-0.6	-0.9	-1.0	-1.3	-0.9	-0.6
Commuting to job workplace: Public transport	1.1	1.3	4.5	0.1	0.2	1.6	0.6	0.8	1.1	0.9	0.8	1.9	0.0	2.1
Schizophrenia (2018)	1.0	2.1	7.1	-0.0	-0.9	-2.7	-0.5	1.2	-1.5	-2.0	-2.1	-1.8	-0.4	0.0
Prostate Cancer	1.0	1.3	3.7	-0.2	1.2	-1.0	-0.9	-1.9	-1.0	-0.8	-0.4	-1.5	-0.2	-1.9
HbA1C	1.0	1.1	3.5	1.1	1.9	1.3	0.4	-1.8	-0.0	-0.1	0.5	1.1	0.5	-0.5
Average weekly spirits intake	1.0	1.2	4.3	1.3	-1.7	-1.2	0.5	-0.2	-1.0	-1.1	0.8	-0.3	-0.1	-2.1
Sensitivity / hurt feelings	1.0	1.8	4.3	1.3	1.5	1.4	1.3	-0.2	1.4	1.3	1.1	2.1	1.5	0.8
Serious illness, injury or assault to yourself	1.0	1.2	4.2	1.2	0.7	-0.3	0.8	-2.1	1.5	1.3	0.6	0.4	1.6	-0.3
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.4	-0.0	0.9	-1.8	-0.6	-1.5	-0.7	-0.5	-1.0	-1.2	0.4	-1.6
Financial difficulties in last 2 years	1.0	1.3	4.5	-1.2	0.1	-2.1	-0.9	0.1	-0.8	-1.0	-1.4	-1.5	-0.4	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	3.2	-0.8	-1.5	-1.8	-0.1	1.8	-0.6	-0.7	-1.2	-1.0	-0.4	-0.8
Pulse wave peak to peak time	1.0	1.1	3.0	1.5	-1.2	1.1	0.4	-1.2	0.7	0.4	1.7	1.4	0.5	-0.3
Eye problems/disorders: None of the above	1.0	1.2	3.8	-0.6	-0.2	-0.7	-1.2	-1.8	-0.4	-0.7	-1.9	-1.2	-0.4	-0.9
Suffer from ‘nerves’	1.0	1.6	5.4	1.0	0.9	0.5	1.4	-0.3	2.1	1.6	0.2	0.8	2.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	7.6	-0.2	-0.4	-1.1	-1.1	-0.8	-1.7	-2.8	-0.3	-0.9	-1.7	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.5	-1.3	0.8	-0.5	-0.7	1.3	-1.1	-1.6	-1.1	-0.5	-1.4	-0.6
Breast cancer (self-reported)	1.0	1.2	3.2	-0.7	-1.3	-1.8	-0.4	1.2	-1.3	-0.8	0.4	-1.1	-1.2	-0.8
Myopia	1.0	1.5	6.8	-1.7	-2.6	-1.3	-0.6	0.9	-0.0	0.3	-1.5	-1.1	0.0	0.3
Neuroticism (Nagel 2018)	0.9	2.2	5.1	1.6	2.3	1.6	1.3	-0.4	1.4	0.7	1.1	2.2	1.8	0.3
Worry (Nagel 2018)	0.9	1.9	4.5	1.4	1.5	1.8	1.3	0.4	1.4	0.9	0.4	2.1	1.7	0.9
Systolic Blood Pressure	0.9	4.7	19.6	-4.4	1.7	-1.8	-3.0	-0.5	-0.7	0.2	-2.4	-2.6	-1.5	1.4
Pain all over the body in last month	0.9	0.9	2.9	0.6	-0.1	-1.7	0.8	1.6	-0.3	-0.2	0.2	-1.1	0.8	-1.3
Worrier / anxious feelings	0.9	1.7	5.2	0.3	0.1	2.2	0.5	-0.3	1.2	1.3	0.6	2.3	0.5	2.0
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.9	0.7	1.3	0.9	1.0	2.0	0.1	0.0	0.6	1.9	0.4	0.4
Peak expiratory flow (PEF)	0.9	2.0	5.1	2.0	1.4	0.2	1.2	1.1	-1.0	-1.6	2.3	0.7	-0.4	-1.9
Number of children fathered	0.9	1.0	2.4	1.1	0.6	0.7	0.4	1.1	-1.0	-1.6	0.8	0.8	-1.1	-1.0
Smoking status: Previous	0.9	1.3	2.4	-0.7	-1.6	-1.2	-0.8	0.8	-1.2	-1.5	-0.6	-1.3	-1.1	-1.2
Commuting to job workplace: Walk	0.9	0.9	2.1	-0.8	-1.4	-0.9	-0.8	0.9	-1.4	-0.6	-0.7	-1.4	-0.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	3.3	1.8	1.4	1.3	1.4	-0.3	1.6	0.8	1.6	1.7	1.7	0.2
Medication: Blood pressure	0.9	1.8	4.4	-2.1	1.4	-1.5	-1.6	-0.7	-0.9	-0.3	-1.4	-2.0	-0.9	-0.3
Medication: Bendroflumethiazide	0.9	1.3	5.3	-2.3	0.7	-0.2	-1.6	-1.0	-0.4	0.5	-1.5	-1.2	-0.5	0.8
Number of operations (self-reported)	0.9	1.3	4.8	2.2	0.4	-0.2	1.7	0.7	0.4	0.4	1.3	0.7	1.4	-1.1
Age started oral contraceptive pill	0.9	1.2	2.8	0.5	1.7	0.9	1.0	0.1	1.0	1.3	1.6	1.1	1.1	0.8
Supplements: Calcium	0.9	1.0	2.0	-0.9	-1.4	0.7	-1.0	-1.2	-1.4	-0.9	-1.2	0.6	-1.0	-0.0
Age at First Birth	0.8	1.1	5.8	0.1	1.0	-0.2	0.9	2.4	1.3	0.8	0.6	0.5	0.5	1.2
Triglycerides	0.8	1.3	3.4	-0.6	-0.1	-1.0	-1.3	-1.9	-0.9	-1.1	-1.0	-1.5	-0.5	-1.5
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	2.1	0.9	1.5	0.7	1.0	1.3	-0.7	0.0	0.6	1.4	0.5	0.2
Mouth/teeth dental problems	0.8	1.2	3.1	-1.6	1.8	0.3	-1.3	-0.9	-1.0	-0.3	-0.5	-0.6	-1.4	0.7
Medication: Ramipril	0.8	1.0	2.9	-1.7	-1.5	-1.0	-1.0	0.4	-0.7	0.3	-1.4	-1.0	-0.3	0.5
Impedance of arm (right)	0.8	3.9	9.2	-0.9	-2.1	-1.8	-0.9	2.5	-2.4	-3.0	0.1	-0.6	-2.9	-2.0
Noisy workplace	0.8	1.0	3.3	0.4	0.9	-1.8	0.9	1.5	0.5	0.2	-0.6	-0.7	1.1	-1.0
Health satisfaction	0.8	1.1	7.3	0.2	-0.2	-1.0	-0.5	-2.7	-0.3	-0.1	-0.7	-0.5	0.8	-1.3
Pulse rate, automated reading	0.8	2.7	6.9	2.5	2.2	0.9	2.1	2.2	-0.4	-0.6	2.6	1.0	-0.2	-0.4
Alcohol intake frequency.	0.8	1.9	6.1	0.2	2.5	1.2	0.1	-2.2	1.2	1.9	0.2	0.3	1.3	1.5
Overall health rating	0.8	1.8	8.2	1.0	-0.7	-1.8	0.2	-1.0	-0.5	-0.9	-1.1	-1.4	1.2	-2.9
Supplements: Vitamin C	0.8	0.9	2.2	-0.9	-1.3	-1.1	-0.7	-0.3	-1.5	-0.7	0.5	-1.0	-1.2	-0.6
Knee pain experienced in last month	0.8	1.3	3.8	-0.5	-0.7	-2.0	-0.8	0.4	-1.1	-1.4	-0.7	-1.2	-0.7	-1.9
Alcohol drinker status: Previous	0.8	0.9	2.3	1.1	-0.2	1.0	0.9	-0.6	0.7	1.5	1.1	0.5	1.3	0.9
Bipolar Disorder (2011)	0.7	0.6	2.1	-0.8	0.1	0.1	-1.2	-0.2	-0.8	-1.0	-1.4	-0.2	-1.2	0.0
HDL Cholesterol	0.7	1.1	3.6	-1.0	-1.7	-0.6	-0.6	0.9	-1.3	-0.9	-1.9	-0.5	-0.8	-0.1
Neuroticism (2016)	0.7	1.0	3.9	-0.2	0.3	-0.6	-0.3	-0.4	-0.0	-1.4	-2.0	-0.4	0.4	-1.9
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.0	1.7	1.0	0.5	1.6	-0.0	0.4	0.6	0.7	-0.0	1.1	0.0
Systolic blood pressure, automated reading	0.7	2.2	6.1	-2.5	1.7	-1.1	-1.4	-0.2	-0.1	0.6	-2.2	-2.2	-0.2	1.1
Angina	0.7	0.9	6.0	0.5	-2.5	-0.3	0.3	-0.3	-0.6	-0.3	-1.3	-0.0	0.5	-0.7
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	3.3	0.7	1.8	0.7	1.2	1.3	-0.3	0.3	1.0	0.6	0.4	0.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.5	1.1	-0.8	-0.6	0.5	-0.7	-0.8	-0.7	0.8	-0.3	-0.0	-1.9
Hearing difficulty/problems with background noise	0.7	1.1	3.8	0.0	1.9	1.0	0.3	-0.2	1.5	1.3	0.2	0.8	1.1	1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.2	-1.4	-0.1	-0.0	-1.4	-1.4	-0.4	-0.3	-1.8	-0.2	-0.5	0.2
Fluid intelligence score	0.7	1.4	3.5	-1.1	-0.6	0.7	-1.5	-0.7	-1.7	-1.2	-1.9	-0.4	-1.5	-0.3
Father’s age at death	0.7	0.9	5.5	1.0	2.3	0.3	1.0	0.9	0.7	0.6	0.4	0.3	0.9	0.2
Pulse rate	0.7	1.2	4.5	1.8	-0.0	0.1	1.6	2.1	-0.0	-0.3	0.8	1.3	0.8	-0.5
Impedance of arm (left)	0.7	3.4	8.3	-0.6	-2.0	-1.5	-0.6	2.5	-2.3	-2.9	0.1	-0.3	-2.7	-1.8
Birth weight of first child	0.7	1.3	3.1	1.8	1.1	0.6	1.6	1.3	1.3	0.3	1.0	1.2	1.2	-0.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.0	-1.1	-0.6	-1.7	-0.8	-0.4	-0.3	-0.0	-1.1	-1.4	-0.1	-0.6
Medication for pain relief, constipation, heartburn	0.7	1.1	4.3	-0.8	-2.1	1.1	-1.2	-1.7	0.3	-0.3	-0.4	-0.1	-1.1	0.7
Medication: Allopurinol	0.7	0.9	3.3	-1.3	-0.6	-1.4	-1.1	-0.4	-0.5	-0.0	-0.1	-1.8	-0.7	-0.4
Mean time to correctly identify matches	0.7	1.3	4.7	-0.5	1.8	1.0	0.5	1.5	0.8	1.2	-0.0	0.8	0.5	2.2
Mood swings	0.7	1.2	4.5	1.4	0.3	1.8	1.0	-0.3	0.6	0.5	0.8	2.1	0.9	0.6
Back pain experienced in last month	0.7	1.0	3.7	-0.6	1.1	0.2	-1.2	-1.9	-0.9	-0.8	-0.4	-0.2	-1.4	-0.5
Osteoporosis (self-reported)	0.7	0.8	2.5	-0.7	0.3	0.9	-0.2	-1.4	0.3	1.5	-0.1	0.4	0.7	1.6
Illnesses of father: High blood pressure	0.7	0.9	4.8	-1.0	2.2	0.8	-0.9	-0.8	-0.2	-0.1	-1.2	0.1	-0.1	0.6
Fractured/broken bones in last 5 years	0.7	0.9	1.9	-0.2	0.4	-1.4	-0.5	-0.5	-1.2	-1.1	0.4	-1.3	-1.2	-1.3
Commuting to job workplace: Cycle	0.7	0.9	2.4	-1.6	-0.7	-1.2	-0.8	0.9	-0.4	-0.2	-1.5	-1.2	-0.1	-0.2
Depression (Nagel 2018)	0.6	0.9	4.0	-0.5	1.4	-0.9	-0.7	-0.8	-0.0	-0.5	-2.0	-0.5	0.8	-0.9
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.2	-1.0	-1.9	-0.3	-1.1	0.5	-2.1	-1.6	-0.1	-0.8	-2.3	-0.6
Hand grip strength (right)	0.6	1.6	6.4	1.3	0.4	-0.4	1.5	-0.4	1.6	1.5	1.1	0.3	2.5	-0.3
Current tobacco smoking	0.6	0.9	4.3	-0.8	-1.3	-2.1	-0.6	-0.2	0.2	0.2	-0.9	-1.3	-0.0	-0.6
Average weekly fortified wine intake	0.6	0.7	4.0	-0.7	0.5	-1.2	0.2	2.0	-0.4	0.5	-0.7	-0.5	0.5	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.6	0.1	-0.6	-1.2	0.6	-0.0	1.0	1.1	-0.8	-0.2	1.9	-0.2
Neuroticism score	0.6	1.2	4.2	1.3	0.5	1.4	1.2	0.2	0.8	0.6	1.1	2.1	1.0	0.4
Hair/balding pattern: Pattern 3	0.6	0.9	2.5	0.4	-0.9	1.2	0.5	-0.0	0.3	0.8	1.6	1.5	0.0	1.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.0	-1.7	-0.8	-0.5	-1.6	-0.6	-0.9	-0.8	-1.5	-0.5	-0.9	-0.1
Medication: Paracetamol	0.6	1.0	6.7	0.6	2.6	-0.6	0.4	0.9	-0.6	-0.5	1.0	-0.2	-0.2	-0.9
Neck or shoulder pain in last month	0.6	0.8	2.7	1.6	1.0	-0.6	0.9	-1.4	0.1	0.4	0.8	-0.2	0.8	-1.0
Angina (self-reported)	0.6	0.8	6.1	0.6	-2.5	-0.1	0.4	-0.2	-0.3	-0.0	-1.0	0.2	0.5	-0.5
Medication: Seretide 50 evohaler	0.6	0.7	1.7	-0.7	-0.1	-0.5	-1.2	-0.9	-0.6	-0.7	-0.8	-1.3	-1.0	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.8	0.3	0.5	-1.1	-0.1	-1.0	-1.0	-0.7	0.2	-0.8	0.1	-1.7
Number of full sisters	0.6	0.8	3.3	-0.9	0.1	-1.3	-0.1	1.5	-0.3	-0.2	-0.6	-1.8	-0.3	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.6	-0.7	0.2	-0.6	-0.8	-1.6	0.0	0.0	-1.6	-0.6	0.6	-0.3
Medication: Gliclazide	0.6	0.7	2.9	-1.0	1.7	-1.2	-0.5	0.3	-0.4	-0.0	-0.9	-1.0	-0.1	-0.4
Illnesses of father: None of the above (group 1)	0.6	0.7	2.0	1.0	0.9	-1.0	1.0	1.4	-0.2	-0.6	0.9	-0.0	-0.2	-0.9
Wears glasses or contact lenses	0.6	0.7	2.7	0.4	1.0	1.1	0.1	-0.1	-0.4	0.3	1.7	0.8	-0.7	0.9
Hearing aid user	0.6	0.6	2.2	0.9	-0.1	-0.5	-0.0	-1.4	-0.8	-0.9	-0.4	-0.1	0.1	-1.5
Medication: Lisinopril	0.6	0.7	2.4	-0.4	0.3	-1.5	-0.3	0.6	-0.8	-0.7	-1.0	-1.3	-0.2	-1.0
Leg fat percentage (left)	0.6	2.0	6.1	2.5	-0.6	-0.4	2.1	0.6	1.5	1.2	0.9	0.3	2.4	-0.4
Irritability	0.6	1.1	3.5	0.5	1.0	1.9	0.7	-0.1	0.5	0.9	0.8	1.7	0.5	1.5
Bipolar Disorder or Schizophrenia	0.5	1.2	3.0	0.5	-0.2	-1.7	-0.2	1.1	-1.3	-1.7	-1.6	-1.3	-0.2	0.0
Alzheimer’s Disease (in father)	0.5	0.5	1.9	-0.1	-0.7	0.1	0.7	1.4	0.5	0.6	0.3	0.8	0.5	1.0
Reaction Time	0.5	0.9	2.4	-1.0	1.5	0.7	-0.1	1.4	-0.2	0.2	-1.2	0.5	-0.2	1.6
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.7	-1.2	-1.1	0.4	-1.3	0.4	-1.5	-1.2	-1.0	-0.5	-1.6	-0.2
Body Mass Index (BMI) (2010)	0.5	0.7	2.1	1.5	-0.3	-0.4	1.3	0.2	0.3	0.7	1.3	0.3	1.0	-0.2
Mean Putamen Volume	0.5	0.6	2.6	-1.2	-0.7	-1.2	-0.1	1.6	-0.5	0.3	-0.1	-0.5	-0.3	0.4
Hand grip strength (left)	0.5	1.3	5.1	1.2	0.4	-1.6	1.4	0.1	1.0	1.0	0.1	-0.7	2.3	-1.0
Diabetes (mother)	0.5	0.7	2.1	-0.8	1.4	0.5	-0.6	-1.0	1.0	0.4	-1.0	-0.5	0.1	0.7
Trunk fat percentage	0.5	1.8	4.9	1.7	-2.2	-1.7	1.3	1.6	-0.2	-0.6	0.3	-0.8	0.7	-1.8
Fed-up feelings	0.5	1.0	2.1	-0.4	-1.1	-0.9	-0.9	-0.5	-1.0	-1.3	-1.4	-0.7	-0.6	-1.2
Sitting height	0.5	3.8	10.7	-2.1	0.0	-1.6	-1.9	1.5	-2.4	-2.9	-0.6	-1.5	-3.3	-1.2
Past tobacco smoking	0.5	0.9	3.3	0.4	1.8	1.5	0.2	-1.1	0.6	0.7	0.2	1.0	0.2	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.5	1.0	0.1	-0.2	0.8	-1.0	1.1	1.0	-0.2	0.4	1.9	-0.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	7.0	1.6	2.6	0.3	1.4	0.6	0.9	0.2	1.6	0.9	1.5	-0.7
Depression (self-reported)	0.5	0.6	1.6	0.8	1.1	0.2	0.7	-0.6	1.0	0.9	1.3	0.4	1.0	0.1
Lung cancer (father)	0.5	0.6	1.3	0.8	0.1	-0.2	0.2	0.4	-1.1	-1.1	0.9	-0.3	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.4	5.9	1.4	2.4	0.7	1.2	0.6	1.0	-0.1	1.6	1.1	0.9	-0.3
Tense / ‘highly strung’	0.5	0.8	1.7	0.4	0.6	1.1	0.9	0.8	1.1	0.9	0.3	1.3	0.9	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.9	-1.0	0.4	1.0	-0.7	-0.9	1.1	0.7	-1.1	0.6	0.3	1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	-1.2	0.5	0.0	-0.9	-1.3	0.2	0.8	-0.3	-0.3	-0.0	1.1
Headache pain in last month	0.5	0.9	5.2	0.6	2.3	0.3	0.9	0.1	0.2	1.1	1.1	0.1	0.5	0.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.2	-0.1	-1.5	0.7	-0.1	-1.2	1.0	1.0	-0.4	0.5	0.6	0.7
Leg fat percentage (right)	0.5	1.9	5.1	2.3	-0.7	-0.6	2.0	0.6	1.6	1.3	0.9	0.1	2.3	-0.4
Number of full brothers	0.5	0.6	2.5	0.7	-0.5	-1.6	0.2	-0.1	-0.1	-0.2	0.4	-0.8	0.4	-1.6
Shortness of breath walking on level ground	0.5	0.6	3.2	-0.2	-0.3	-0.2	-0.3	-1.8	0.7	1.0	-0.3	-0.4	0.9	0.3
Comparative height size at age 10	0.5	2.8	5.2	-1.8	0.8	-2.1	-1.7	-0.1	-1.5	-2.2	-1.1	-2.3	-1.9	-1.7
Chest pain or discomfort	0.5	0.7	1.9	1.4	0.1	-0.0	0.8	-1.1	0.9	1.0	0.5	0.4	1.4	-0.4
Hypertension (Self-reported)	0.5	1.4	6.5	-1.5	2.5	-0.1	-0.2	0.4	0.5	1.2	-1.3	-0.9	0.7	1.4
Long-standing illness, disability or infirmity	0.5	0.8	2.9	-0.5	-0.8	-1.2	-1.0	-1.7	-0.3	0.1	-0.1	-1.1	-0.1	-0.7
Friendships satisfaction	0.5	0.6	2.1	-1.5	0.4	-0.1	-0.9	-1.1	0.5	0.9	-0.8	-0.2	0.4	0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	2.1	1.4	-1.4	-0.8	1.0	0.2	0.6	0.6	1.3	0.1	1.1	-0.3
Medication: Aspirin	0.5	0.6	3.0	0.5	1.7	0.6	0.9	0.4	0.3	0.9	0.2	0.5	0.8	0.7
Supplements: Fish oil (including cod liver oil)	0.5	0.6	3.2	1.1	-0.6	0.5	0.7	-0.8	0.6	0.2	1.8	0.5	0.4	-0.5
Average weekly beer plus cider intake	0.5	0.8	3.8	0.2	-1.9	-0.4	0.6	0.5	1.4	0.7	0.6	0.6	0.7	0.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.4	0.7	0.2	1.2	0.5	1.2	-0.4	-0.4	0.8	1.1	-0.6	0.3
Vascular/heart problems diagnosed by doctor	0.5	1.3	4.3	1.9	-1.6	0.5	1.0	0.3	0.3	-0.5	2.1	1.2	-0.2	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.2	0.7	0.1	-0.9	0.7	-0.2	1.1	1.0	0.6	0.1	1.5	-0.3
Leg fat mass (left)	0.5	1.9	6.0	2.5	-0.6	-0.6	2.1	0.6	1.4	1.1	0.9	-0.1	2.3	-0.6
Ulcerative Colitis (UC)	0.4	0.8	2.3	1.5	-0.3	0.8	1.0	1.5	-0.4	-1.0	0.6	0.7	-0.2	-0.7
Breast Cancer	0.4	1.1	3.2	0.6	-0.6	0.5	1.0	1.2	1.8	0.9	-0.4	0.9	1.7	0.8
Fasting Glucose	0.4	0.5	1.3	0.9	0.3	0.7	1.0	1.1	0.8	-0.0	0.8	0.2	0.8	-0.1
LDL Cholesterol	0.4	0.7	2.2	1.5	1.0	0.4	1.2	1.1	-0.1	-0.1	0.9	0.4	0.4	-0.6
Smoking Status	0.4	1.1	3.9	-0.4	-2.0	-1.8	-0.5	0.6	-0.8	-0.7	-0.4	-1.2	-0.6	-1.0
Hypothyroidism (self reported)	0.4	1.0	3.1	0.1	0.0	-0.7	-0.8	-1.1	-1.8	-1.2	-0.3	-1.3	-0.9	-1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.6	1.2	1.1	0.6	0.8	-0.8	0.2	0.5	1.2	0.7	0.8	-0.3
Lung FVC	0.4	2.0	7.5	-0.7	0.0	0.3	-0.8	-2.7	2.2	1.8	-0.3	0.4	1.9	1.0
Neuroticism	0.4	1.0	3.0	1.3	1.4	1.3	0.7	-0.4	0.5	-0.2	0.8	1.7	0.6	-0.4
Frequency of depressed mood in last 2 weeks	0.4	0.6	3.2	-0.1	0.5	-0.8	-0.0	-0.2	0.9	0.1	-1.8	-0.6	1.2	-0.5
Relative age of first facial hair	0.4	0.7	3.5	1.9	-0.2	-0.5	1.3	0.0	0.6	0.2	1.0	-0.0	0.8	-0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.9	1.4	0.1	0.1	0.4	-0.4	-0.5	-0.6	1.2	0.2	-0.0	-1.0
Supplements: Zinc	0.4	0.4	1.2	-1.1	-0.7	-0.8	-0.1	0.5	0.0	0.6	-0.9	-0.4	-0.0	0.7
Medication: Co-codamol	0.4	0.4	1.8	0.8	0.9	0.5	0.7	0.1	0.2	0.5	1.4	0.4	-0.1	0.0
High blood pressure	0.4	1.2	4.4	-1.5	2.1	-0.2	-0.3	0.1	0.4	1.2	-1.3	-0.9	0.8	1.2
Stomach or abdominal pain in last month	0.4	0.5	2.1	-0.4	0.8	-0.5	-0.4	-1.4	0.5	0.4	-1.1	-0.3	0.8	-0.3
Supplements: Glucosamine	0.4	0.5	1.9	0.3	1.4	0.1	0.1	0.7	-0.6	-0.9	0.6	-0.0	-0.9	-0.9
High blood pressure (mother)	0.4	0.6	2.5	-1.1	1.6	-0.5	-0.6	-0.3	-0.5	-0.4	-1.2	-0.4	0.2	-0.5
Number of incorrect matches in round	0.4	0.7	2.1	1.2	0.9	0.0	1.2	0.6	0.3	0.7	1.5	0.9	0.7	0.1
Falls in the last year	0.4	0.5	1.1	-0.6	0.3	-0.9	-0.6	-0.8	1.0	0.5	-1.1	-0.5	0.8	0.1
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.8	-1.1	-1.9	0.2	-1.1	-0.6	-1.1	-0.4	-0.5	0.1	-0.8	0.0
Exposure to tobacco smoke at home	0.4	0.4	2.1	-0.2	-1.0	-1.5	-0.2	-0.2	0.3	0.1	-0.2	-0.7	0.4	-0.7
Birth weight	0.4	0.9	4.0	1.3	-0.4	0.5	1.1	0.4	0.9	0.4	2.0	1.0	0.6	-0.0
Body fat percentage	0.4	1.6	3.9	2.0	-1.7	-1.4	1.7	1.2	0.5	0.1	0.5	-0.5	1.4	-1.3
Comparative body size at age 10	0.4	1.2	4.6	1.1	0.0	0.3	1.3	-0.3	1.5	1.4	0.1	0.7	2.2	0.6
Medication: Blood pressure	0.4	0.7	2.8	-0.8	-1.7	-0.4	-0.0	1.2	0.3	0.6	-1.2	-0.4	0.6	0.6
Leg fat mass (right)	0.4	1.7	5.2	2.3	-0.4	-0.7	2.0	0.6	1.4	1.1	0.9	-0.2	2.2	-0.6
Had major operations	0.4	0.4	1.8	0.6	-0.3	0.0	0.7	1.3	0.4	0.2	-0.9	0.2	0.9	0.1
Family relationship satisfaction	0.4	0.5	1.7	-1.2	-0.9	0.4	-0.6	-0.6	0.2	0.4	-0.4	0.5	-0.7	1.3
Leg pain on walking	0.4	0.4	1.1	0.4	0.5	-0.1	0.9	0.8	0.6	1.0	0.1	0.4	1.0	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.6	0.3	0.7	-0.9	-0.4	-1.0	-0.4	-0.7	-0.2	-0.7	-0.2	-1.3
Guilty feelings	0.4	0.6	1.6	0.4	0.4	0.5	0.8	1.3	0.8	0.3	1.2	1.0	0.2	0.5
High cholesterol (Self-reported)	0.4	0.8	2.0	1.0	-0.7	1.4	0.8	-0.5	0.5	0.6	1.4	1.1	0.1	0.7
Medication: Paracetamol	0.4	0.7	5.2	0.4	2.3	-0.2	0.2	0.6	-0.4	-0.5	0.7	0.2	-0.3	-0.7
Ever smoked	0.4	0.7	2.8	-0.6	-1.1	-1.7	0.1	1.6	0.1	0.1	-0.2	-0.7	0.1	-0.1
Ever depressed for a whole week	0.4	0.5	1.7	-1.1	-0.5	-0.3	-0.9	-0.6	0.3	-0.1	-1.3	-0.5	-0.4	0.3
Unable to work because of sickness or disability	0.4	0.5	1.8	0.6	-0.0	-0.8	0.3	-0.8	0.4	0.9	-0.3	-0.7	1.4	-0.6
Cholesterol lowering medication	0.4	0.5	1.4	0.3	0.9	-0.9	-0.2	-1.0	-0.4	-0.6	-0.0	-0.9	-0.4	-1.2
Basal cell carcinoma (self-reported)	0.4	0.5	1.6	0.2	-0.3	1.2	0.1	-0.1	0.5	0.0	1.3	0.9	-0.8	0.8
Impedance of whole body	0.4	2.2	7.3	0.5	-1.1	-1.0	0.3	2.7	-1.4	-2.3	0.8	0.2	-1.8	-1.7
Depressed Affect (Nagel 2018)	0.3	0.7	2.1	1.2	0.7	1.1	0.5	-0.8	0.6	0.0	0.4	1.4	0.9	-0.3
Alzheimer’s Disease (in mother)	0.3	0.3	1.2	-0.6	1.1	-0.1	-0.3	-0.1	0.7	0.6	0.4	-0.3	-0.0	0.7
Primary Biliary Cirrhosis	0.3	0.4	1.1	-0.9	0.3	0.3	-0.6	-0.7	0.7	0.7	-0.3	-0.5	-0.1	1.1
Rheumatoid Arthritis	0.3	0.5	1.5	-0.8	0.1	-1.0	-0.6	0.4	-0.4	-0.4	-1.2	-1.1	-0.2	-0.3
Heel T-Score	0.3	2.0	5.0	1.1	2.0	2.1	0.5	-2.2	0.1	0.7	-1.1	1.5	1.9	-0.1
Cardiovascular Disease	0.3	1.1	6.2	-1.6	2.5	-0.3	-0.6	-0.7	-0.0	0.7	-0.6	-1.0	-0.0	0.8
Respiratory disease	0.3	0.8	4.4	1.0	0.3	0.2	-0.2	-2.1	-0.7	-0.4	0.6	0.1	0.3	-1.3
Ever had hysterectomy (womb removed)	0.3	0.4	2.9	0.1	1.7	-0.3	0.5	0.3	-0.3	0.3	0.6	0.2	0.4	-0.1
Severe depression (siblings)	0.3	0.4	1.3	-0.6	0.9	-0.1	-0.2	0.0	0.6	0.6	-1.1	-0.5	0.5	0.7
Maternal smoking around birth	0.3	0.5	2.4	-0.6	-1.5	-1.0	-0.2	0.1	0.0	0.5	-0.0	-1.0	-0.1	0.1
Relative age voice broke	0.3	0.5	1.8	1.3	-0.9	0.1	0.9	0.6	-0.3	-0.3	0.7	0.3	-0.3	-0.5
Medication: Atenolol	0.3	0.4	1.4	0.0	-0.7	-1.1	-0.2	0.1	-0.5	-0.4	-0.4	-0.2	0.1	-1.2
Body mass index (BMI)	0.3	1.1	3.8	1.5	-1.1	-0.3	1.3	-0.3	1.2	1.3	0.2	-0.2	2.0	-0.1
Impedance of leg (left)	0.3	1.3	3.8	1.7	0.9	0.1	1.2	2.0	0.1	-0.7	1.8	1.0	-0.2	-0.6
Trunk fat mass	0.3	1.4	2.8	1.7	-1.4	-1.5	1.4	1.4	0.2	-0.2	0.5	-0.8	1.0	-1.4
Forced vital capacity (FVC)	0.3	1.1	4.4	1.0	0.9	0.2	0.8	-0.6	1.6	0.9	0.8	0.8	2.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.6	0.9	0.8	-0.5	0.4	-0.9	-0.2	0.1	-1.0	-0.1	1.3	-1.1
Allergy	0.3	0.8	3.9	-0.2	0.2	-0.6	0.0	2.0	-1.2	-0.9	-0.4	-0.9	-0.8	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.5	-0.1	0.6	1.0	0.3	-0.1	0.8	0.3	0.3	1.2	0.3	0.4
Arm fat percentage (right)	0.3	1.1	4.7	1.0	-2.2	-1.5	0.8	0.6	0.2	0.0	-0.1	-0.9	0.9	-1.2
Time employed in main current job	0.3	0.4	1.5	0.4	0.7	0.4	0.1	-0.8	1.2	0.6	0.7	0.4	0.7	0.3
Alcohol intake versus 10 years previously	0.3	0.5	2.6	-0.3	1.6	-0.4	-0.5	-0.6	-0.8	-0.4	-0.4	-0.5	-0.4	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.4	0.6	-0.0	-1.1	0.5	-0.4	0.0	0.0	0.6	-0.3	0.9	-1.2
Asthma	0.3	0.5	3.9	0.1	-0.4	0.8	-0.5	-2.0	0.3	0.5	-0.6	0.3	0.6	-0.0
Medication: Cholesterol lowering	0.3	0.5	1.1	-0.4	-1.0	0.8	-0.4	0.4	-1.0	-0.9	-1.0	0.0	-0.9	0.1
Length of working week for main job	0.3	0.3	1.1	-0.2	0.6	0.7	0.2	-0.5	0.6	0.6	-0.0	0.1	0.1	1.0
Breastfed as a baby	0.3	0.3	1.5	1.2	0.4	0.1	0.5	0.2	-0.8	-0.7	-0.0	0.0	-0.0	-0.8
Glaucoma (self-reported)	0.3	0.3	0.7	-0.1	0.7	-0.4	-0.4	-0.2	-0.6	-0.8	-0.3	-0.7	-0.6	-0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.4	-0.1	-0.4	-0.6	-0.9	-1.2	-0.9	-0.9	-0.1	-1.2	-0.7	-0.7
Whole body fat mass	0.3	1.2	3.0	1.7	-1.0	-1.3	1.4	0.8	0.6	0.3	0.5	-0.8	1.4	-1.1
Arm fat percentage (left)	0.3	1.0	3.9	1.2	-2.0	-1.4	0.9	0.6	0.2	-0.0	-0.1	-0.8	0.9	-1.2
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.0	-1.0	-1.0	-0.3	-0.7	-0.3	-0.5	0.2	-0.1	-0.1	-0.6	0.4
Loneliness, isolation	0.3	0.4	1.4	-0.7	-0.5	-0.7	-0.7	0.2	-0.6	-0.7	-1.2	-0.6	-0.3	-0.6
Eye problems/disorders: Cataract	0.3	0.3	1.4	0.7	-0.2	0.6	0.6	0.4	-0.4	0.1	1.2	0.7	0.0	0.1
Mineral and other dietary supplements	0.3	0.4	2.1	-0.7	0.6	0.1	-0.3	0.7	-0.4	-0.0	-1.5	-0.5	-0.0	0.5
Asthma (self-reported)	0.3	0.5	3.9	0.0	-0.3	0.7	-0.5	-2.0	0.3	0.3	-0.7	0.2	0.6	-0.2
Smoking status: Current	0.3	0.5	2.0	-0.4	-1.2	-1.4	0.0	0.3	0.8	0.7	-0.3	-0.5	0.4	-0.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.7	0.3	-0.4	-0.6	-0.3	-0.1	0.5	-0.9	-0.3	-0.7	0.1	-1.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.7	0.5	-0.9	0.6	0.5	0.8	0.1	0.4	0.7	0.8	0.5	0.4
Pain experienced in last month	0.3	0.6	2.4	0.2	-0.9	1.5	0.3	-0.1	0.7	0.4	0.1	0.8	0.3	1.2
Heart disease (siblings)	0.3	0.4	3.8	0.6	-2.0	0.0	-0.1	-0.5	-0.2	0.2	-0.1	-0.3	0.2	-0.0
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	-0.8	0.6	-0.6	-0.2	1.1	0.3	0.4	-0.1	-0.2	-0.1	0.7
Irritable Bowel Disease (IBD)	0.2	0.4	1.0	0.8	0.0	-0.0	0.4	1.0	-0.9	-1.0	0.4	0.6	-0.1	-0.7
Ulcerative Colitis	0.2	0.3	1.0	0.3	-0.2	-0.2	0.1	1.0	-0.4	-1.0	-0.0	-0.3	-0.5	0.0
Blood Eosinophil Count	0.2	1.4	3.4	0.7	-1.3	1.7	0.6	0.7	-1.2	-0.8	1.0	1.5	-1.9	0.9
Blood White Count	0.2	1.6	4.3	-1.5	0.1	-1.5	-1.5	-1.7	0.2	0.0	-2.1	-2.0	-0.1	-0.5
BMI	0.2	1.0	2.4	1.4	-1.4	-0.5	0.7	-1.3	0.5	0.9	-0.3	-0.9	1.6	-0.5
Allergy or Eczema	0.2	0.5	2.1	0.4	-0.4	0.2	0.7	-0.1	0.5	0.3	1.2	1.4	0.4	0.3
Hearing difficulty/problems: Yes	0.2	0.3	0.7	-0.1	0.8	-0.2	0.1	0.4	0.8	0.3	-0.4	0.7	0.7	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.3	-0.3	0.3	0.4	-0.7	-0.1	-0.6	-0.9	-0.2	-0.1	-1.1	-0.2
Pack years adult smoking proportion	0.2	0.3	0.9	-0.4	-0.3	-0.3	-0.4	-0.7	0.2	0.7	0.9	0.3	-0.3	0.9
Impedance of leg (right)	0.2	0.9	4.0	1.2	0.7	-0.2	0.9	2.0	0.2	-0.7	1.5	0.6	-0.4	-0.6
Leg fat-free mass (left)	0.2	0.9	3.5	-0.4	-0.4	-1.9	-0.4	-0.2	-0.4	-0.3	-0.8	-1.8	0.2	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.8	0.9	0.3	-0.8	0.8	-0.0	0.1	0.3	-0.4	-0.5	1.4	-1.0
Qualifications: CSEs or equivalent	0.2	0.3	1.2	-1.1	-0.3	-1.1	-0.5	0.0	0.1	-0.1	-0.7	-0.3	-0.0	-0.2
Multivitamins +/- minerals	0.2	0.3	1.0	0.2	0.5	-1.0	-0.1	-0.1	-0.4	-0.4	-0.1	-0.6	0.1	-1.0
Leg predicted mass (left)	0.2	0.9	3.6	-0.5	-0.4	-1.9	-0.4	-0.3	-0.4	-0.4	-0.8	-1.8	0.1	-1.2
Waist circumference	0.2	0.8	3.0	0.9	-1.7	-1.2	0.6	-0.3	0.2	0.2	-0.2	-1.0	1.0	-1.0
Alcohol usually taken with meals	0.2	0.4	1.5	0.2	1.2	-0.7	0.0	0.6	-0.6	0.1	1.0	-0.5	-0.5	0.0
Had menopause	0.2	0.3	0.9	-0.4	0.7	0.3	-0.0	0.6	0.6	0.7	-0.4	-0.6	0.4	0.9
Qualifications: None of the above	0.2	0.4	1.2	1.0	0.8	0.0	0.7	0.3	-0.2	-0.5	0.5	0.0	0.1	-1.1
Hip circumference	0.2	0.7	3.4	0.7	-1.8	-0.1	0.8	0.7	1.1	0.8	0.1	0.3	0.9	0.6
Number of live births	0.2	0.3	2.5	0.0	1.6	0.3	-0.1	-0.5	-0.2	-0.2	-0.6	-0.1	0.4	-0.4
Arm fat mass (right)	0.2	1.0	2.5	1.2	-1.4	-1.6	0.8	0.2	0.4	0.2	0.0	-1.2	1.1	-1.2
Standing height	0.2	1.6	4.3	-0.3	1.2	-1.6	-0.3	2.1	-0.8	-1.8	0.6	-1.0	-1.5	-1.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.2	1.0	1.1	-0.0	0.5	-0.4	0.3	0.0	0.9	0.4	0.2	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	2.8	0.5	1.0	0.4	0.4	-1.1	1.7	0.6	0.5	0.8	1.5	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.0	-0.6	-0.3	-0.3	-0.1	0.4	0.4	0.3	-1.0	-0.2	0.3	0.4
Age at first live birth	0.2	0.4	1.5	0.3	-0.6	0.5	0.3	-0.5	0.9	0.8	1.2	0.5	0.5	0.4
Age at last live birth	0.2	0.3	1.1	-0.4	0.9	0.1	-0.4	-1.1	0.3	0.4	0.0	0.0	0.6	0.0
Medication: Aspirin	0.2	0.3	2.0	0.3	1.4	0.3	0.6	0.6	-0.3	0.2	-0.2	0.1	0.3	0.2
Leg fat-free mass (right)	0.2	0.8	3.0	-0.4	-0.3	-1.7	-0.4	-0.5	-0.6	-0.5	-0.9	-1.6	0.1	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.2	0.8	0.1	-0.0	0.2	-0.3	0.5	-0.1	0.5	0.5	0.6
Osteoarthritis (self-reported)	0.2	0.3	1.1	0.4	1.1	0.5	-0.1	-0.3	-0.9	-0.3	0.6	0.5	-0.5	-0.0
Leg predicted mass (right)	0.2	0.9	3.3	-0.5	-0.4	-1.8	-0.5	-0.5	-0.7	-0.6	-1.0	-1.7	0.0	-1.2
Arm fat mass (left)	0.2	0.8	1.8	1.1	-1.3	-1.3	0.8	0.1	0.5	0.3	-0.0	-1.0	1.1	-0.9
Eye problems/disorders: Glaucoma	0.2	0.3	0.6	0.8	0.6	-0.0	0.2	-0.5	-0.5	-0.5	0.8	-0.1	-0.4	-0.6
Alcohol drinker status: Never	0.2	0.2	1.3	0.4	1.1	0.6	0.1	-0.2	0.0	-0.2	-0.3	0.2	-0.5	0.2
Pack years of smoking	0.2	0.3	1.1	-0.3	-0.2	-0.2	-0.3	-0.4	0.3	0.9	0.9	0.4	-0.2	1.0
Bipolar Disorder (2018)	0.1	0.2	0.6	0.8	0.8	0.5	0.3	0.2	-0.2	-0.3	0.1	0.2	0.1	0.0
Crohns Disease (2017)	0.1	0.2	0.9	-0.2	0.2	-0.6	-0.3	0.3	-0.9	-0.3	-0.0	0.5	0.2	-0.1
Ovarian Cancer	0.1	0.2	1.0	-0.2	-0.3	-0.6	0.0	0.7	-0.1	-0.1	0.3	-1.0	-0.0	-0.2
Crohns Disease (2012)	0.1	0.2	1.2	-0.5	0.0	0.0	0.2	0.8	-0.3	0.6	0.2	1.1	0.1	0.0
Height	0.1	2.5	10.0	0.9	3.2	-0.2	1.3	2.3	1.7	0.3	2.4	0.1	0.6	0.3
Tanning	0.1	1.0	2.9	-1.2	0.1	-1.6	-1.1	-1.7	-0.2	0.2	0.0	-1.7	-0.2	-0.5
Number of treatments/medications taken	0.1	0.2	1.8	0.0	1.4	0.5	-0.0	0.1	-0.2	-0.1	0.2	0.2	-0.3	0.1
Taking other prescription medications	0.1	0.2	1.3	0.3	1.1	0.0	0.2	0.1	0.9	0.2	0.3	-0.3	0.2	0.3
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.6	-0.4	-0.2	-0.0	-0.0	-0.3	0.4	0.2	0.6	0.8	-0.0	0.4
Hair/balding pattern: Pattern 2	0.1	0.1	0.3	0.6	0.0	0.2	0.3	0.2	0.0	-0.3	0.3	-0.1	0.1	-0.2
Medication: Simvastatin	0.1	0.2	0.8	0.5	0.9	0.5	0.5	0.0	0.4	0.3	0.0	0.2	0.6	0.2
Illnesses of siblings	0.1	0.2	0.5	0.1	0.7	-0.3	0.7	0.2	0.3	0.5	0.5	0.1	0.5	0.3
Weight	0.1	0.7	1.5	1.2	-0.5	-1.0	1.1	0.5	0.8	0.5	0.4	-0.6	1.2	-0.5
Trunk fat-free mass	0.1	0.6	2.9	-0.3	1.7	-0.9	-0.2	-0.3	0.6	0.6	-0.2	-1.2	0.5	0.2
Trunk predicted mass	0.1	0.6	2.9	-0.3	1.7	-0.9	-0.2	-0.3	0.5	0.6	-0.1	-1.3	0.4	0.2
Medication: Amlodipine	0.1	0.2	1.1	-0.3	1.0	0.5	-0.1	-0.2	-0.5	0.0	-0.1	-0.2	-0.0	-0.2
High blood pressure (siblings)	0.1	0.2	0.4	-0.5	-0.2	0.6	-0.6	-0.6	-0.1	-0.1	-0.3	-0.0	-0.4	0.2
Arm fat-free mass (right)	0.1	0.6	1.5	0.8	1.2	-0.7	0.6	-0.7	0.7	0.6	-0.0	-0.9	1.2	-0.4
Arm predicted mass (right)	0.1	0.6	1.7	0.6	1.3	-0.9	0.5	-0.4	0.6	0.6	-0.1	-1.1	1.1	-0.3
Illnesses of siblings: Diabetes	0.1	0.2	0.7	-0.4	0.7	-0.0	-0.4	0.5	0.8	0.0	-0.2	-0.3	-0.2	0.1
Whole body fat-free mass	0.1	0.5	2.4	-0.3	0.9	-1.4	-0.2	-0.3	0.0	0.1	-0.5	-1.5	0.4	-0.5
Average weekly red wine intake	0.1	0.2	1.0	0.6	-1.0	0.1	0.5	0.2	0.2	0.2	0.2	0.0	0.5	-0.2
Whole body water mass	0.1	0.5	2.0	-0.1	0.9	-1.2	-0.1	-0.5	0.2	0.2	-0.4	-1.4	0.5	-0.5
Number of self-reported non-cancer illnesses	0.1	0.2	1.0	-0.3	1.0	-0.2	-0.2	-0.2	-0.6	0.4	0.6	-0.3	-0.1	0.2
Miserableness	0.1	0.2	0.7	-0.5	-0.4	-0.0	-0.5	-0.8	-0.0	-0.0	-0.8	0.6	0.1	-0.2
Basal metabolic rate	0.1	0.5	2.2	0.1	0.5	-1.4	0.1	-0.2	0.3	0.2	-0.3	-1.5	0.6	-0.7
Arm fat-free mass (left)	0.1	0.5	1.5	0.5	0.9	-0.9	0.3	-0.4	0.7	0.6	0.2	-1.2	0.9	-0.3
Arm predicted mass (left)	0.1	0.6	1.4	0.9	1.0	-0.9	0.7	-0.2	0.7	0.6	0.2	-1.1	1.2	-0.5
Hair Pigment	0.0	0.3	1.9	-0.6	-1.4	0.4	-0.5	0.2	-0.4	-0.2	-0.7	0.4	-0.2	0.5
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	-0.4	0.4	0.1	0.1	0.5	0.5	0.2	0.5	-0.1	-0.3	0.2

Hub : Genes

ATP5O

Models

Trait associations