TWAS hub - ATR

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0770	0.0360	1.1e-02	-0.002	0.004	0.036	0.016	0.002	6.5e-01	0.098	3.3e-05	0.0044	1.5e-01
2	GTEx	Adipose Subcutaneous	0.0580	0.0240	9.2e-05	0.035	NA	0.058	NA	0.054	7.5e-04	NA	1.5e-05	NA	3.1e-05
3	GTEx	Artery Tibial	0.0680	0.0298	1.1e-03	0.030	NA	0.033	NA	0.031	1.9e-03	NA	1.2e-03	NA	1.8e-03
4	GTEx	Brain Cerebellar Hemisphere	0.1010	0.0520	8.8e-03	0.056	NA	-0.011	NA	0.035	1.5e-02	NA	9.1e-01	NA	4.5e-02
5	GTEx	Brain Cerebellum	0.1350	0.0760	9.0e-03	0.065	NA	-0.006	NA	0.026	5.7e-03	NA	5.1e-01	NA	5.8e-02
6	GTEx	Esophagus Mucosa	0.0690	0.0310	4.5e-04	0.039	NA	0.018	NA	0.037	1.3e-03	NA	2.2e-02	NA	1.7e-03
7	GTEx	Lung	0.0887	0.0346	9.4e-05	0.034	NA	0.027	NA	0.032	1.2e-03	NA	3.7e-03	NA	1.7e-03
8	GTEx	Nerve Tibial	0.1182	0.0372	5.1e-08	0.109	NA	0.097	NA	0.116	4.1e-08	NA	2.4e-07	NA	1.4e-08
9	GTEx	Testis	0.1460	0.0600	2.5e-04	0.127	NA	0.119	NA	0.102	2.9e-06	NA	6.4e-06	NA	2.9e-05
10	GTEx	Thyroid	0.0620	0.0290	9.2e-04	0.025	NA	0.028	NA	0.029	4.5e-03	NA	3.2e-03	NA	2.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Blood Red Count	18.6	179.4	262.4	-1.3	-14.5	-8.6	-11.4	-16.0	-13.8	-13.7	-16.2	-15.8	-15.2
Fractured/broken bones in last 5 years	7.1	9.2	12.9	0.2	3.4	2.7	3.0	3.3	3.6	2.9	3.1	3.0	3.6
Alzheimer’s Disease (in father)	6.6	7.2	11.3	1.4	2.6	1.9	2.6	3.4	2.8	1.9	3.2	3.1	3.1
Past tobacco smoking	5.3	9.7	15.8	0.0	3.2	1.6	2.2	4.0	3.5	3.5	3.7	3.7	3.4
Financial difficulties in last 2 years	4.3	5.8	12.3	1.2	-2.8	-3.5	-2.1	-1.7	-2.3	-2.9	-2.3	-2.2	-2.4
Number of live births	4.3	6.1	9.1	1.0	-2.3	-1.6	-2.5	-3.0	-2.6	-2.6	-2.8	-2.9	-2.7
Hearing difficulty/problems with background noise	3.6	5.7	8.4	-0.4	-2.8	-2.0	-2.2	-2.6	-2.5	-2.0	-2.9	-2.5	-2.9
Illnesses of siblings	3.6	5.0	7.7	0.6	2.4	1.9	1.9	2.7	1.7	2.3	2.5	2.6	2.8
Medication: Cholesterol lowering	3.6	5.7	10.8	-2.3	2.1	-0.0	2.5	3.3	3.0	2.3	1.9	2.3	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.6	4.3	7.8	2.8	-2.1	-1.1	-2.1	-2.5	-1.8	-1.7	-2.1	-2.1	-1.9
Ever smoked	3.2	5.6	10.1	-0.2	-2.5	-1.3	-1.8	-3.2	-2.6	-2.8	-2.7	-2.6	-2.5
Illness, injury, bereavement, stress in last 2 years	3.1	3.8	9.6	-0.8	2.5	3.1	1.1	1.3	1.9	2.3	1.8	1.7	2.0
Supplements: Zinc	2.9	3.1	6.3	-0.3	-2.1	-1.8	-2.5	-1.8	-1.6	-1.7	-1.7	-1.6	-1.9
Commuting to job workplace: Walk	2.8	3.0	5.7	-2.1	-1.8	-1.7	-0.8	-1.4	-1.1	-2.4	-1.7	-1.7	-2.0
Chronic bronchitis/emphysema (father)	2.7	3.1	4.8	-0.1	1.9	1.4	1.6	1.9	2.0	1.6	2.0	2.2	1.9
Medication for cholesterol, blood pressure or diabetes	2.7	4.5	8.7	2.3	-1.9	-0.4	-2.2	-3.0	-2.5	-2.3	-1.6	-2.0	-2.1
Medication for hormone replacement therapy	2.6	2.9	5.1	0.6	2.3	0.5	0.5	2.0	1.6	2.2	2.1	1.8	2.0
Father’s age at death	2.6	3.5	9.1	-0.6	0.9	-0.6	2.4	3.0	2.0	1.5	1.9	2.2	1.8
Smoking status: Previous	2.5	3.7	7.2	-0.1	-1.8	-0.7	-1.5	-2.7	-2.3	-2.2	-2.2	-2.2	-2.0
Bilateral oophorectomy (both ovaries removed)	2.4	2.8	3.8	-0.9	1.9	1.6	1.9	1.3	2.0	1.8	1.6	1.4	1.9
Commuting to job workplace: Public transport	2.4	2.8	4.3	1.0	2.0	2.1	0.6	1.7	2.0	1.1	1.9	1.7	2.0
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	5.0	-0.8	1.9	1.2	2.2	2.2	1.7	1.7	1.8	1.9	1.5
Townsend deprivation index at recruitment	2.3	3.2	5.5	1.6	-1.9	-0.9	-2.1	-2.0	-1.3	-2.3	-1.7	-1.7	-2.1
Alcohol intake frequency.	2.3	5.4	11.1	-1.5	2.2	0.1	2.8	3.3	2.6	1.9	2.5	2.5	2.1
Medication: Simvastatin	2.2	3.2	8.6	-0.4	1.5	-1.1	1.4	2.9	2.3	0.9	1.9	2.3	1.6
Blood clot in the leg (DVT)	2.2	2.8	4.4	-0.6	1.8	1.3	2.0	2.1	1.5	1.7	1.8	1.9	1.5
Number of full brothers	2.2	2.8	5.3	-0.3	-1.5	-0.9	-1.4	-2.2	-1.5	-1.9	-2.0	-2.3	-1.6
Wheeze or whistling in the chest in last year	2.2	3.9	9.7	-1.7	-2.2	-3.1	-2.1	-1.6	-2.0	-0.3	-1.6	-1.5	-2.4
Medication: Seretide 50 evohaler	2.2	2.5	8.0	1.5	-1.3	-2.3	-2.8	-1.0	-1.3	-0.7	-1.0	-0.6	-1.7
Tinnitus: Yes, now most or all of the time	2.2	2.6	4.3	-0.0	-1.8	-0.7	-1.9	-1.6	-1.2	-2.1	-1.9	-1.6	-2.1
Medication: Lisinopril	2.2	2.9	5.5	1.9	1.7	1.3	1.4	1.8	2.3	0.8	1.9	1.7	1.8
Primary Biliary Cirrhosis	2.1	3.0	5.8	-1.0	-1.8	-1.8	-2.1	-1.7	-2.4	-0.3	-1.8	-1.5	-1.9
Triglycerides	2.1	3.4	6.5	1.2	1.6	0.3	1.5	2.5	2.1	2.1	1.8	2.3	1.9
Had menopause	2.1	2.6	5.9	-0.5	1.0	2.1	2.4	0.9	1.8	1.9	1.4	1.6	1.4
Mean time to correctly identify matches	2.1	4.0	7.8	0.4	1.6	1.0	1.7	2.4	2.1	2.5	2.4	2.8	1.8
Alcohol intake versus 10 years previously	2.0	2.9	7.1	0.7	1.4	-0.4	1.6	2.7	2.0	1.6	2.1	1.9	1.6
Heart disease (mother)	2.0	2.4	5.4	2.3	1.4	0.6	1.1	1.7	1.5	1.6	1.5	1.7	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	5.6	-0.4	2.1	1.7	1.2	1.2	1.5	2.4	1.3	1.0	1.7
LDL Cholesterol	1.9	3.1	6.3	-0.1	1.6	0.8	1.9	2.5	2.0	1.3	2.0	2.1	1.8
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.5	0.5	1.5	0.5	0.9	2.1	1.5	1.7	1.8	2.0	1.3
Illnesses of father: None of the above (group 1)	1.9	2.3	5.4	0.2	-1.1	-0.2	-2.1	-2.3	-1.6	-1.2	-1.5	-1.8	-1.6
Angina	1.8	2.4	6.3	-0.1	-1.3	-1.4	-2.5	-1.9	-1.4	-0.7	-1.7	-1.4	-1.7
Shortness of breath walking on level ground	1.8	2.1	5.3	-0.5	1.2	1.4	2.3	1.2	1.2	1.6	1.5	1.6	1.6
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	4.6	-0.5	2.2	1.3	1.4	1.8	1.4	0.7	2.0	1.3	1.6
Ever used hormone-replacement therapy (HRT)	1.7	2.1	3.6	-0.1	1.9	1.2	1.0	1.4	1.1	1.9	1.9	1.6	1.7
Pulse rate	1.7	2.9	6.7	-0.7	1.2	0.7	2.6	2.3	2.0	1.4	1.4	1.8	1.8
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	5.5	1.5	-1.1	-0.5	-2.4	-1.6	-2.0	-0.5	-1.0	-1.3	-1.5
Eye problems/disorders: Cataract	1.7	2.0	3.5	-0.2	-1.5	-1.0	-0.7	-1.9	-1.3	-1.8	-1.5	-1.3	-1.9
Miserableness	1.7	3.0	4.6	1.4	-1.7	-2.1	-2.1	-1.5	-1.6	-1.1	-1.8	-1.5	-2.1
Heart disease (siblings)	1.7	2.1	4.1	0.3	-1.6	-0.8	-1.2	-2.0	-1.3	-1.4	-1.7	-1.8	-1.5
Medication: Lansoprazole	1.6	1.8	3.1	-0.1	1.7	1.8	1.3	1.4	1.1	1.5	1.4	0.7	1.5
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	4.9	1.0	-1.9	-1.7	-0.9	-1.0	-1.2	-2.2	-1.5	-1.3	-1.4
Alcohol drinker status: Previous	1.6	1.9	3.0	-0.5	1.5	1.1	1.7	1.7	1.4	0.4	1.6	1.7	1.2
Pack years of smoking	1.6	2.3	3.8	-0.6	1.5	1.5	1.9	1.5	1.9	1.4	1.6	1.5	1.4
Unable to work because of sickness or disability	1.5	1.9	6.2	-2.5	1.1	0.5	1.0	1.6	1.3	0.9	1.3	1.6	1.0
Blood White Count	1.4	10.2	18.7	-4.1	2.1	-0.1	4.1	4.3	3.0	3.4	2.5	3.3	2.7
Multivitamins +/- minerals	1.4	1.8	3.5	0.7	-1.4	-0.5	-0.7	-1.7	-0.8	-1.8	-1.6	-1.4	-1.9
Time employed in main current job	1.4	1.6	3.2	0.7	1.7	1.6	0.6	1.0	0.9	1.0	1.4	1.2	1.8
Hair/balding pattern: Pattern 4	1.4	3.3	6.1	0.5	1.5	-0.3	1.5	2.4	2.0	2.3	2.2	2.5	1.7
Ever highly irritable/argumentative for 2 days	1.4	1.7	4.6	-0.6	1.0	0.5	2.1	1.6	1.2	1.5	1.1	1.4	0.8
Number of children fathered	1.4	1.6	4.6	-0.3	-1.1	-0.3	-1.5	-2.1	-1.5	-0.4	-1.3	-1.2	-1.3
Angina (self-reported)	1.4	1.8	5.0	-0.0	-1.1	-1.3	-2.2	-1.6	-1.1	-0.6	-1.5	-1.2	-1.4
Asthma (self-reported)	1.4	2.8	7.6	-0.9	-1.8	-2.8	-1.9	-0.9	-1.8	-1.0	-1.3	-1.3	-2.0
Respiratory disease	1.3	2.9	6.4	-1.8	-1.7	-2.5	-2.3	-1.0	-2.0	-0.7	-1.1	-1.1	-1.9
Average weekly spirits intake	1.3	1.7	2.8	0.4	1.5	1.6	1.2	1.1	1.7	0.7	1.3	1.1	1.6
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	3.9	-1.0	1.1	0.3	0.8	1.3	1.0	2.0	1.4	1.0	1.1
Vitamin and mineral supplements	1.3	1.7	2.8	-0.8	1.5	1.0	0.2	1.5	1.1	1.6	1.5	1.3	1.7
Asthma	1.3	2.6	7.1	-1.0	-1.8	-2.7	-1.8	-0.9	-1.8	-1.1	-1.3	-1.2	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.4	0.0	1.6	2.1	1.5	1.4	1.8	0.2	1.5	1.2	1.5
Breast cancer (self-reported)	1.3	1.5	2.4	-0.4	-1.5	-0.4	-0.6	-1.4	-1.4	-1.4	-1.5	-1.6	-1.3
Osteoporosis (self-reported)	1.3	1.7	2.8	-0.2	1.5	1.3	1.0	1.7	0.8	1.4	1.6	1.3	1.4
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.5	0.5	-1.4	-0.7	-1.0	-1.8	-1.1	-1.2	-1.4	-1.2	-1.9
Vascular/heart problems diagnosed by doctor	1.3	3.6	9.7	0.2	2.3	3.1	1.6	1.6	1.6	1.0	2.2	1.8	2.1
Loneliness, isolation	1.2	1.6	2.8	0.7	1.6	1.3	0.8	1.1	1.7	0.9	1.6	1.5	1.2
Major Depression (MDD)	1.1	1.3	4.2	0.4	-0.9	-0.1	-0.8	-0.9	-1.2	-2.1	-1.3	-1.3	-1.3
Qualifications: CSEs or equivalent	1.1	1.5	3.2	-0.0	-0.9	-1.6	-1.8	-1.1	-0.9	-0.6	-1.4	-1.5	-1.4
Medication: Amlodipine	1.1	1.5	5.1	-2.3	1.0	-0.2	0.9	1.1	0.6	2.1	0.8	0.8	1.0
Exposure to tobacco smoke outside home	1.1	1.5	13.6	-3.7	-0.1	-0.8	0.5	-0.0	0.5	-0.6	0.0	-0.4	-0.3
Medication: Blood pressure	1.1	1.9	4.0	-1.2	1.3	-0.1	1.2	2.0	1.6	1.9	1.1	1.2	1.4
Had major operations	1.1	1.2	3.1	-0.7	-1.0	-1.8	-1.4	-0.9	-1.2	-0.8	-0.9	-1.2	-0.9
Friendships satisfaction	1.1	1.4	4.1	-0.1	-1.4	-2.0	-1.0	-0.6	-1.0	-1.3	-1.0	-0.7	-1.3
Qualifications: nursing, teaching	1.1	1.7	5.6	-0.1	1.4	2.4	1.1	1.0	1.2	0.5	1.4	1.3	1.5
Basal cell carcinoma (self-reported)	1.1	1.3	3.0	1.7	-1.0	-1.0	-1.4	-1.2	-0.8	-0.8	-1.1	-1.0	-0.9
Ever had hysterectomy (womb removed)	1.0	1.1	2.1	-0.3	1.1	1.1	1.5	1.0	1.2	1.1	1.0	1.0	1.0
Diabetes (father)	1.0	1.2	3.8	0.8	-0.1	-1.7	0.9	1.9	1.2	1.1	0.8	0.9	0.4
Average weekly fortified wine intake	1.0	1.2	6.2	-0.9	0.7	2.5	1.6	-0.2	1.2	-0.2	-0.1	0.4	0.5
Birth weight	1.0	2.1	9.5	1.4	1.9	3.1	0.9	0.1	0.9	0.1	0.9	0.6	1.8
Pulse rate, automated reading	1.0	3.3	10.8	-1.3	1.0	-0.3	3.3	2.8	1.5	1.2	1.3	1.7	1.8
Ever taken oral contraceptive pill	1.0	1.1	2.6	-1.4	0.8	-1.1	-0.1	1.6	0.9	0.9	1.2	1.1	0.7
Financial situation satisfaction	1.0	1.2	3.2	0.3	-0.9	-0.7	-1.8	-1.5	-1.7	-0.6	-0.5	-0.9	-1.1
Body Mass Index (BMI) (2010)	0.9	1.2	6.4	0.5	1.5	2.5	0.1	0.3	0.8	0.3	0.9	0.2	1.3
Smoking Status	0.9	2.2	3.5	0.3	-1.6	-0.4	-0.9	-1.9	-1.4	-1.9	-1.9	-1.8	-1.7
Diabetes (mother)	0.9	1.1	2.5	-1.3	1.0	0.6	1.6	0.7	1.3	1.2	0.7	0.6	1.0
Severe depression (siblings)	0.9	1.0	3.2	0.6	-1.0	-1.8	-1.0	-0.4	-0.3	-1.3	-0.7	-0.4	-1.4
Pack years adult smoking proportion	0.9	1.4	2.2	-0.4	1.1	1.1	1.3	1.2	1.5	1.1	1.4	1.2	1.1
High blood pressure	0.9	2.4	8.6	0.1	-2.0	-2.9	-1.0	-1.0	-1.3	-0.5	-1.7	-1.4	-1.7
Medication: Atenolol	0.9	1.1	3.5	1.3	-0.8	-1.9	-1.7	-0.5	-0.7	-0.4	-0.8	-0.4	-1.0
Peak expiratory flow (PEF)	0.9	2.2	5.2	2.3	0.1	1.4	-1.4	-1.7	-0.8	-2.2	-1.0	-1.4	-0.9
Headache pain in last month	0.9	1.5	6.9	-1.1	-1.1	-2.6	-1.3	-0.3	-0.9	-0.0	-1.1	-0.9	-1.3
High blood pressure (siblings)	0.9	1.3	2.4	-0.2	-1.2	-1.1	-0.9	-1.6	-0.5	-1.2	-1.4	-1.4	-1.4
Commuting to job workplace: Cycle	0.9	1.1	3.4	-0.1	-1.0	-1.2	-1.8	-0.7	-1.2	-0.2	-0.9	-1.1	-1.1
Alzheimer’s Disease (including proxy)	0.8	1.2	2.8	0.9	0.7	0.5	1.3	1.7	1.2	0.8	1.2	1.1	1.1
Reaction Time	0.8	1.5	3.1	0.1	0.9	0.2	0.8	1.6	1.3	1.8	1.3	1.7	1.0
Crohns Disease (2012)	0.8	1.3	3.8	2.0	-0.7	-1.5	-1.8	-0.6	-0.9	-0.9	-0.7	-0.6	-0.9
Hearing difficulty/problems: Yes	0.8	1.3	2.4	-0.8	-1.2	-1.1	-1.0	-1.0	-1.4	-1.0	-1.1	-1.0	-1.6
Medication: Co-codamol	0.8	0.9	2.0	-0.1	1.2	1.4	0.1	0.6	0.6	1.2	1.1	0.9	1.0
Comparative body size at age 10	0.8	2.1	4.8	-0.2	-1.3	-0.0	-1.5	-2.2	-1.7	-1.6	-1.8	-1.4	-1.4
Hypertension (Self-reported)	0.8	2.2	9.0	0.4	-2.0	-3.0	-0.8	-0.8	-1.0	-0.4	-1.5	-1.1	-1.7
Illnesses of siblings: Diabetes	0.8	1.0	2.7	-0.9	-1.2	-1.6	-0.5	-0.5	-0.6	0.2	-1.3	-0.9	-1.3
Diabetes diagnosed by doctor	0.8	1.3	3.3	-1.3	0.7	0.6	1.7	0.9	1.8	1.5	0.6	0.8	0.7
Osteoarthritis (self-reported)	0.8	1.0	3.5	1.9	1.2	1.2	-0.3	0.5	0.6	0.9	1.0	0.5	0.9
Wears glasses or contact lenses	0.8	1.0	2.5	-0.3	0.5	0.3	1.6	1.4	0.8	0.3	1.0	1.4	0.9
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.2	1.2	-0.9	0.4	-1.1	-1.6	-2.1	-1.3	-1.1	-1.6	-0.6
Mean Putamen Volume	0.7	0.8	3.3	0.2	1.1	1.0	-0.2	0.6	0.8	1.8	0.6	0.5	0.8
Hayfever, allergic rhinitis or eczema	0.7	1.6	2.9	1.1	1.1	0.0	1.3	1.6	1.1	1.1	1.7	1.6	1.3
Sitting height	0.7	4.8	13.7	1.0	-0.8	2.1	-0.9	-3.7	-1.4	-3.5	-2.4	-2.5	-1.0
Alcohol usually taken with meals	0.7	1.2	2.0	1.0	1.0	0.9	0.9	1.3	1.1	0.1	1.1	1.4	1.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.4	-0.6	0.9	0.8	0.9	1.2	1.1	1.1	1.1	1.0	0.9
Hair/balding pattern: Pattern 3	0.7	1.0	3.6	-1.9	-1.1	-0.4	0.0	-0.6	-0.9	-0.7	-1.0	-1.0	-1.2
Illnesses of mother	0.7	0.8	3.7	-1.9	-0.4	-0.9	-0.9	-0.7	-1.2	-0.1	-0.5	-0.6	-0.6
Breastfed as a baby	0.7	0.8	3.5	-1.9	0.1	-1.8	0.2	0.9	-0.1	0.4	0.3	0.6	-0.1
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	2.7	0.3	1.6	1.4	0.8	0.8	1.5	0.4	1.1	0.7	1.1
Age at first live birth	0.7	1.2	3.1	-0.6	1.1	1.8	1.4	0.9	0.9	0.7	0.5	1.1	1.5
Migraine (self-reported)	0.7	0.9	1.7	0.6	-1.3	-0.5	-0.5	-0.9	-0.8	-1.3	-1.0	-1.1	-1.1
Comparative height size at age 10	0.7	3.6	9.9	-1.1	-0.8	1.3	-1.3	-2.9	-1.4	-3.1	-2.0	-2.2	-1.2
Family relationship satisfaction	0.7	0.9	2.7	0.6	-1.2	-1.6	-1.3	-0.2	-1.0	-0.1	-0.4	-0.0	-1.1
Supplements: Vitamin C	0.7	0.9	4.1	-0.7	-1.0	-2.0	-0.6	-0.2	-0.7	-0.6	-0.7	-0.7	-0.9
Medication for cholesterol	0.7	1.1	2.4	-1.5	-1.1	0.2	-0.4	-1.3	-1.1	-0.8	-1.3	-1.0	-1.1
Mineral and other dietary supplements	0.7	1.0	2.9	-0.4	1.2	0.6	0.7	1.3	0.5	0.7	1.0	0.8	1.7
Number of operations (self-reported)	0.7	1.0	4.6	-2.2	-0.7	-0.7	-0.9	-1.1	-1.0	-0.1	-0.8	-0.9	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.1	-0.7	-1.5	-1.3	0.2	-0.8	-0.4	-0.2	-1.1	-0.7	-1.0
Pain experienced in last month	0.7	1.1	2.0	-0.1	1.3	1.4	0.8	1.3	0.9	1.0	0.9	0.9	1.4
Schizophrenia vs Biploar Disorder	0.6	0.7	1.5	0.5	1.2	0.1	0.6	1.2	1.0	0.2	1.1	0.6	1.0
Blood Eosinophil Count	0.6	4.9	10.1	-3.2	0.6	-1.1	2.6	3.0	2.1	2.3	1.9	2.4	1.5
Allergy or Eczema	0.6	1.5	2.9	0.4	0.9	-0.1	1.6	1.7	1.3	0.9	1.7	1.6	1.0
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.9	-1.1	0.5	-0.2	1.6	1.3	1.7	0.9	0.6	0.8	0.6
Taking other prescription medications	0.6	0.8	2.6	-1.6	0.5	-0.3	0.6	1.1	0.3	1.5	0.9	0.7	0.6
High blood pressure (mother)	0.6	0.8	2.1	0.8	-0.8	0.0	-0.7	-1.4	-0.5	-0.9	-1.1	-1.3	-0.8
Nervous feelings	0.6	1.1	2.2	-0.6	0.7	0.7	1.4	1.0	1.1	1.5	1.0	1.1	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.9	-0.3	-1.2	-1.4	-0.6	-0.5	-0.9	-0.6	-0.8	-0.7	-1.0
Medication: Ibuprofen	0.6	0.7	3.1	1.8	-0.4	0.1	-1.4	-0.8	-1.0	0.1	-0.0	-0.2	-0.5
Age at last live birth	0.6	0.9	2.0	1.1	-0.7	-0.0	-0.6	-1.0	-0.7	-1.4	-1.4	-0.9	-0.6
Number of self-reported non-cancer illnesses	0.6	1.1	2.5	-1.3	0.7	0.4	1.6	1.4	1.1	0.9	1.0	0.6	0.7
Eye problems/disorders: Glaucoma	0.6	0.7	1.4	-0.8	-0.7	-0.9	-1.1	-0.9	-1.2	0.1	-0.8	-0.6	-0.8
Medication: Blood pressure	0.6	1.1	3.8	0.9	-1.4	-2.0	-1.0	-0.7	-0.8	-0.8	-0.7	-0.6	-1.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	4.9	-2.2	-0.4	-1.0	-0.2	0.4	-0.8	0.0	-0.2	-0.2	-0.5
Ulcerative Colitis (UC)	0.5	0.9	5.6	-1.4	-0.0	2.4	0.7	-0.8	-0.2	-0.4	-0.2	-0.0	-0.0
Ulcerative Colitis	0.5	0.7	1.4	-0.9	-0.7	0.6	-0.1	-0.9	-1.0	-1.2	-0.9	-0.5	-0.8
Maternal smoking around birth	0.5	0.7	1.4	0.7	-0.5	-0.3	-1.1	-1.2	-0.3	-0.3	-1.1	-1.1	-0.9
Age when periods started (menarche)	0.5	1.2	2.2	0.3	1.5	1.3	0.8	1.3	1.1	0.7	1.1	1.1	1.4
Allergy	0.5	1.0	2.1	-0.6	-0.8	0.3	-1.1	-1.4	-0.4	-0.9	-1.4	-1.4	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	3.0	1.7	1.1	1.4	0.1	-0.1	0.7	0.5	0.6	0.5	0.8
Depression (self-reported)	0.5	0.7	1.8	0.3	1.0	-0.4	0.3	1.3	1.0	0.5	1.0	0.9	0.7
Standing height	0.5	4.7	12.9	0.5	-0.6	2.3	-1.0	-3.6	-1.6	-3.5	-2.3	-2.4	-1.0
Exposure to tobacco smoke at home	0.5	0.5	4.1	-2.0	0.1	-0.6	0.4	-0.2	0.1	-0.5	-0.3	-0.2	-0.3
Gout (self-reported)	0.5	0.7	2.9	-0.0	0.1	-1.3	0.6	1.0	0.2	1.7	0.5	0.8	0.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.8	0.7	-0.6	-1.2	-1.7	-0.4	-0.9	0.4	-0.2	-0.1	-0.7
Number of full sisters	0.5	0.5	1.7	0.7	-0.2	-0.3	-1.3	-0.5	-0.7	-0.4	-0.7	-1.2	-0.6
Suffer from ‘nerves’	0.5	0.7	2.0	-0.0	0.2	-0.5	1.2	1.4	1.0	0.7	0.9	1.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	0.9	3.3	1.8	0.4	1.3	-0.9	-1.1	-0.3	-1.3	-0.3	-0.6	0.2
Leg fat-free mass (right)	0.5	2.6	7.9	0.1	-0.4	0.4	-2.8	-2.8	-1.7	-1.1	-1.5	-1.7	-0.9
Average weekly red wine intake	0.5	0.7	1.2	-1.0	-0.8	-0.6	-1.0	-0.8	-1.1	-0.2	-1.0	-0.7	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.8	1.7	0.3	0.5	0.7	0.6	0.5	-0.6	0.5	0.5	0.7
Back pain experienced in last month	0.5	0.8	1.6	-1.2	1.0	-0.4	0.5	1.1	0.7	0.3	1.3	1.2	0.5
Leg predicted mass (right)	0.5	2.4	7.6	0.1	-0.4	0.5	-2.7	-2.7	-1.7	-1.0	-1.4	-1.6	-0.8
High cholesterol (Self-reported)	0.5	0.8	2.3	-0.7	-0.1	-1.5	0.9	1.5	1.5	-0.0	0.0	0.7	0.2
Average weekly beer plus cider intake	0.5	0.7	3.0	1.7	-0.5	-1.0	-1.0	-0.4	-0.1	-0.7	-0.4	-0.2	-0.9
Age started oral contraceptive pill	0.5	0.6	1.0	-0.6	0.8	0.8	0.9	0.5	0.6	0.7	1.0	1.0	0.8
Bipolar Disorder (2018)	0.4	0.6	2.1	0.2	0.6	1.2	0.5	0.7	1.5	1.2	0.1	0.5	0.3
Ovarian Cancer	0.4	0.5	1.7	-0.9	0.0	1.3	-0.7	-0.7	0.1	-0.6	-0.6	-1.0	-0.4
Prostate Cancer	0.4	0.5	2.5	-0.6	-0.5	-1.6	-0.9	0.7	0.4	0.3	-0.2	0.2	-0.4
Age at First Birth	0.4	0.6	1.6	-1.3	0.5	0.6	0.7	0.8	-0.1	1.1	0.7	0.9	0.6
HbA1C	0.4	0.5	1.8	1.3	-0.2	-0.0	-0.7	-0.7	0.3	-1.2	-0.3	-0.5	-0.1
HDL Cholesterol	0.4	0.7	3.2	-1.8	0.8	0.7	1.0	0.4	0.3	0.2	1.0	0.7	0.6
Lupus	0.4	0.7	3.1	1.8	-0.3	0.7	-0.6	-0.3	-0.8	-1.4	-0.2	-0.2	-0.4
Cardiovascular Disease	0.4	1.2	5.9	-0.0	-1.2	-2.4	-0.9	-0.3	-0.4	-0.6	-1.3	-0.6	-1.1
Sensitivity / hurt feelings	0.4	0.6	2.2	1.5	1.1	1.3	0.2	0.5	0.3	0.5	0.5	0.4	0.6
Relative age of first facial hair	0.4	0.9	1.7	-0.2	0.9	1.2	1.3	0.8	0.7	0.8	1.1	1.0	1.0
Systolic blood pressure, automated reading	0.4	1.1	2.1	1.2	-0.0	-0.6	1.4	1.5	0.9	1.2	0.7	1.2	0.6
Medication: Metformin	0.4	0.6	4.0	-2.0	-0.6	-0.9	0.4	-0.0	-0.1	0.1	-0.6	-0.4	-0.4
Leg fat-free mass (left)	0.4	2.0	7.1	0.4	-0.1	0.4	-2.7	-2.5	-1.5	-0.8	-1.2	-1.4	-0.5
Leg predicted mass (left)	0.4	2.2	7.3	0.3	-0.2	0.3	-2.7	-2.6	-1.6	-0.8	-1.3	-1.5	-0.6
Had other major operations	0.4	0.5	2.5	-1.2	-0.4	0.5	1.6	-0.4	0.2	-0.9	0.0	-0.1	0.2
Forced vital capacity (FVC)	0.4	1.4	3.1	1.7	-0.2	1.1	-1.4	-1.4	-0.5	-1.8	-0.7	-0.9	-0.8
Pain all over the body in last month	0.4	0.4	2.0	-1.4	-0.7	-0.3	0.1	-0.5	-0.4	-0.3	-0.6	-0.7	-0.5
Medication: Ramipril	0.4	0.5	0.9	-0.8	0.2	-0.8	0.9	0.9	0.7	0.8	0.7	0.9	0.4
Impedance of arm (right)	0.4	1.7	6.3	1.5	-1.3	0.8	0.7	-1.2	-0.6	-2.5	-1.3	-1.3	-0.9
Length of working week for main job	0.4	0.4	3.2	1.8	-0.0	-0.3	-0.8	-0.4	0.2	-0.2	0.1	0.0	-0.1
Pulse wave reflection index	0.4	0.5	1.1	1.1	-0.4	-0.8	-0.8	-0.8	-0.8	-0.3	-0.2	-0.1	-0.7
Health satisfaction	0.4	0.5	1.4	-0.4	0.5	-0.5	0.9	1.2	-0.2	0.6	0.7	0.8	0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.4	-0.2	-0.2	0.2	-0.4	-1.2	-0.9	0.2	-1.0	-0.9	-0.6
Knee pain experienced in last month	0.4	0.7	1.8	0.9	-1.0	-1.3	-0.2	-0.9	-0.4	-0.4	-0.7	-0.4	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.9	0.7	0.7	0.4	0.7	0.9	0.7	1.0	0.6	0.5	0.8
Medication: Gliclazide	0.4	0.5	1.2	0.2	-1.0	-1.1	-0.8	-0.4	-0.2	-0.8	-0.7	-0.3	-0.7
Smoking status: Current	0.4	0.7	1.5	0.1	-1.1	-0.5	-0.7	-0.8	-0.6	-0.6	-0.9	-1.2	-0.9
Average weekly champagne plus white wine intake	0.4	0.6	2.0	0.9	-0.6	-0.4	-1.4	-0.4	-0.9	-0.8	-0.5	-0.2	-0.6
Guilty feelings	0.4	0.6	2.5	1.0	-0.2	0.2	-1.6	-0.9	-0.7	0.1	-0.6	-0.6	-0.5
Medication: Paracetamol	0.4	0.7	2.7	-0.2	0.4	-0.6	-1.2	0.2	-0.6	1.7	0.8	0.9	0.3
Illnesses of father: High blood pressure	0.4	0.5	1.3	-0.0	-0.4	-1.0	-1.1	-0.2	-0.7	-0.7	-0.5	-0.5	-0.8
Bipolar Disorder or Schizophrenia	0.3	0.7	2.3	-0.5	0.9	0.4	0.6	1.3	1.5	0.7	0.5	0.7	0.5
Crohns Disease (2017)	0.3	0.6	4.2	2.0	-0.2	-0.2	-0.8	-0.7	-0.3	-0.6	-0.3	-0.5	-0.3
Bipolar Disorder (2011)	0.3	0.3	1.1	-1.1	-0.1	-0.3	-0.2	-0.2	-0.1	1.0	-0.5	-0.1	-0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	0.3	-0.1	-0.1	0.9	0.7	1.0	0.2	0.2	0.4	0.4
Heel T-Score	0.3	2.1	7.5	-2.6	-0.8	-2.7	0.3	1.3	0.1	1.8	0.4	0.7	0.2
Neuroticism	0.3	0.8	1.4	0.4	-0.9	-1.0	-0.9	-1.0	-0.8	0.1	-1.1	-0.9	-1.2
Number of treatments/medications taken	0.3	0.5	2.2	-0.9	0.6	-0.2	0.0	0.8	0.1	1.5	0.7	0.5	0.3
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.6	0.2	-0.3	-1.6	-1.0	0.4	0.1	0.0	0.0	-0.1	-0.5
Impedance of leg (right)	0.3	1.5	7.7	0.9	0.0	-0.2	2.8	1.8	1.3	-1.0	0.3	0.6	0.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.4	0.5	-0.5	0.6	0.7	-0.5	-0.5	-1.2	-0.1	-0.1	-0.1
Serious illness, injury or assault to yourself	0.3	0.3	1.3	-1.1	-0.2	-0.9	-0.0	0.1	-0.6	-0.2	-0.3	-0.0	-0.6
Medication: Levothyroxine sodium	0.3	0.5	1.4	1.0	-0.4	0.3	-0.8	-1.0	-1.2	-0.1	-0.3	-0.7	-0.7
Impedance of leg (left)	0.3	1.2	6.3	0.8	-0.6	-0.3	2.5	1.3	1.1	-1.4	-0.2	0.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.6	-0.9	0.2	-1.1	0.1	0.8	0.2	1.3	0.4	0.7	0.4
Hair/balding pattern: Pattern 2	0.3	0.4	0.9	0.7	0.8	0.6	-0.9	-0.1	0.5	0.8	0.3	-0.1	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.5	-0.4	0.8	0.4	1.0	1.0	0.5	1.1	1.1	1.2	0.9
Mouth/teeth dental problems	0.3	0.4	1.6	-1.3	-0.0	0.2	1.1	0.5	0.2	0.9	0.2	0.1	0.3
Diabetes (self-reported)	0.3	0.5	1.6	-1.3	-0.3	-0.2	1.2	0.2	1.0	0.8	-0.1	0.1	-0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.3	0.6	0.5	1.1	0.4	0.2	0.6	0.1	0.8	0.6	0.7
Fluid intelligence score	0.3	0.7	4.0	0.8	0.5	2.0	-0.2	-0.9	-0.7	-0.4	-0.1	-0.7	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.1	-0.9	0.6	-0.8	0.2	1.1	0.5	0.8	0.8	0.6	0.5
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	4.0	2.0	0.3	1.1	-1.0	-0.9	-0.1	-1.5	-0.4	-0.7	-0.3
Lung cancer (father)	0.3	0.4	2.4	0.2	0.4	1.5	-0.0	-0.9	0.3	0.3	-0.4	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	5.1	1.4	1.2	2.3	0.4	0.0	0.7	-0.6	0.5	0.2	0.8
Impedance of arm (left)	0.3	1.4	5.9	1.0	-0.9	1.1	0.6	-1.1	-0.6	-2.4	-1.1	-1.3	-0.7
Tense / ‘highly strung’	0.3	0.5	1.9	-0.6	0.4	-0.5	0.3	0.9	-0.3	1.4	0.7	0.8	0.3
Medication: Paracetamol	0.3	0.5	2.1	0.1	0.3	0.1	-1.1	0.1	-0.7	1.4	0.6	0.5	0.2
Leg fat percentage (right)	0.3	1.2	2.5	0.1	0.8	-1.3	0.7	1.6	1.2	1.5	0.8	1.1	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.1	-0.5	0.5	0.8	1.0	0.3	0.6	-0.4	0.4	0.5	0.4
Qualifications: College or University degree	0.3	0.9	3.8	0.8	-0.5	0.7	-0.4	-1.2	-0.8	-1.9	-0.7	-0.9	-0.2
Medication for pain relief, constipation, heartburn	0.3	0.6	2.1	-0.4	-0.0	0.6	1.5	0.8	0.9	-1.1	0.2	0.3	0.6
Medication: Omeprazole	0.3	0.4	0.8	-0.5	-0.9	-0.8	0.4	-0.6	0.1	0.5	-0.7	-0.4	-0.7
Overall health rating	0.3	0.6	4.4	-0.3	-0.0	-2.1	-0.3	0.8	-0.1	0.9	0.4	0.3	-0.1
Chest pain or discomfort	0.3	0.5	2.7	-1.1	-0.6	-1.6	0.2	0.0	0.3	-0.3	-0.3	-0.1	-0.5
Long-standing illness, disability or infirmity	0.3	0.4	2.1	-1.4	0.6	-0.3	-0.1	1.0	0.4	-0.3	0.5	0.5	0.3
Medication: Aspirin	0.3	0.3	1.7	-0.9	0.2	-1.3	-0.6	-0.2	-0.0	0.3	-0.2	-0.3	-0.3
Mother’s age at death	0.3	0.4	1.9	1.3	0.1	1.4	0.5	-0.2	-0.0	-0.1	0.2	0.3	0.3
Medication: Bendroflumethiazide	0.3	0.5	2.4	1.1	-0.6	-1.6	-0.8	0.3	-0.2	-0.4	-0.2	-0.2	-0.5
Medication: Atorvastatin	0.3	0.3	0.9	-0.9	-0.3	-0.6	0.3	0.2	0.8	0.9	-0.4	-0.3	-0.1
Alcohol drinker status: Never	0.3	0.3	1.1	-0.2	0.4	-0.7	-0.1	1.0	0.4	0.3	0.8	0.9	0.1
Myopia	0.3	0.4	1.0	-0.5	0.5	-0.0	0.0	1.0	0.8	1.0	0.5	0.2	0.9
Cholesterol lowering medication	0.3	0.5	2.8	1.7	-0.3	-1.0	0.4	0.6	0.6	-0.6	0.1	0.3	0.0
Supplements: Calcium	0.3	0.3	1.7	-1.3	-0.4	0.2	0.5	-0.4	-0.3	-0.6	-0.1	-0.2	-0.3
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	0.3	-0.2	-1.1	-1.0	-0.4	-0.5	0.5	-0.5	-0.4	-0.7
Depression (Nagel 2018)	0.2	0.2	1.1	-0.6	0.2	-1.1	0.0	0.6	0.5	0.4	0.2	0.4	0.2
Neuroticism (Nagel 2018)	0.2	0.5	1.5	0.2	-0.5	-1.2	-0.9	-0.5	-0.8	0.5	-0.7	-0.6	-0.9
Schizophrenia (2018)	0.2	0.4	1.2	-0.5	0.7	-0.5	0.3	1.1	0.7	-0.1	0.6	0.5	0.3
Worry (Nagel 2018)	0.2	0.5	1.2	-1.1	0.3	-0.7	0.8	0.9	0.4	1.0	0.6	0.7	0.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	0.5	-0.6	-0.5	0.1	0.1	0.1	-0.6	-0.4	-0.5	-0.5
Breast Cancer	0.2	0.4	1.8	-0.8	-0.4	-1.3	-1.0	-0.3	-0.4	-0.6	0.3	-0.3	-0.2
Fasting Glucose	0.2	0.3	1.3	0.8	0.0	1.1	0.5	-0.3	0.7	-0.3	0.1	-0.1	0.3
Rheumatoid Arthritis	0.2	0.2	0.7	0.4	0.7	0.8	0.7	0.3	0.3	0.1	0.5	0.3	0.4
Height	0.2	4.2	18.2	2.5	1.2	4.3	-0.5	-3.0	-0.1	-2.0	-0.7	-1.1	0.7
Waist Hip Ratio (WHR)	0.2	0.7	3.5	1.9	0.5	-1.0	-0.2	1.1	0.2	0.7	0.6	0.6	0.4
Hypothyroidism (self reported)	0.2	0.4	2.0	1.4	-0.2	0.4	-0.6	-0.4	-0.8	0.5	-0.0	-0.4	-0.1
Lung FEV1/FVC ratio	0.2	1.1	4.1	2.0	0.9	0.7	0.9	0.8	1.0	-1.0	0.8	0.4	1.1
Chronotype (morning person)	0.2	0.5	2.0	1.4	-0.6	-0.5	-1.0	-0.5	-0.3	-0.7	-0.4	-0.3	-0.6
Relative age voice broke	0.2	0.4	1.1	-1.1	-0.6	-0.8	-0.0	-0.5	-0.5	0.7	-0.5	-0.2	-0.5
Stomach or abdominal pain in last month	0.2	0.2	1.0	-0.7	-0.3	-1.0	0.4	-0.1	-0.4	-0.1	0.4	0.1	-0.3
Number of incorrect matches in round	0.2	0.3	1.3	0.1	-0.4	-0.7	0.7	0.3	-0.0	1.1	0.4	0.3	0.1
Trunk fat-free mass	0.2	1.0	3.1	-0.4	0.2	0.2	-1.7	-1.8	-1.1	-0.6	-0.9	-0.9	-0.3
Noisy workplace	0.2	0.2	1.5	-1.2	0.2	-0.4	0.6	-0.0	0.4	-0.2	-0.0	0.1	-0.3
Pulse wave Arterial Stiffness index	0.2	0.3	1.7	1.3	0.4	0.4	0.2	-0.0	0.6	-0.0	0.4	0.5	0.2
Trunk predicted mass	0.2	1.1	3.6	-0.5	0.1	0.2	-1.7	-1.9	-1.1	-0.8	-1.0	-1.0	-0.4
Birth weight of first child	0.2	0.3	1.3	0.7	0.8	1.1	0.1	-0.1	-0.5	-0.7	-0.0	-0.1	0.3
Glaucoma (self-reported)	0.2	0.3	1.3	0.6	-0.2	-1.1	-0.4	0.1	-0.0	0.6	0.3	0.5	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.7	4.4	0.9	0.9	2.1	0.1	-0.3	0.4	-0.7	0.3	0.0	0.4
Worry too long after embarrassment	0.2	0.3	0.9	1.0	-0.3	-0.2	-0.2	-0.5	-0.4	-0.3	-0.5	-0.5	-0.7
Pulse wave peak to peak time	0.2	0.3	1.4	-1.2	-0.3	-0.1	-0.2	-0.2	-0.6	-0.1	-0.4	-0.6	-0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	-0.4	0.1	-0.7	0.7	0.8	0.3	-0.7	0.3	0.5	0.2
Emphysema/chronic bronchitis	0.2	0.3	1.0	0.5	0.4	-0.1	-1.0	-0.2	-0.6	0.8	0.3	0.0	0.3
Medication: Allopurinol	0.2	0.2	1.1	-0.5	-0.4	-0.8	-0.1	-0.1	-0.4	1.0	-0.0	0.1	-0.2
Medication: Aspirin	0.2	0.2	1.6	0.1	0.3	-1.3	-0.8	-0.0	0.1	0.1	-0.1	-0.1	-0.2
Illnesses of father: Heart disease	0.2	0.3	0.7	0.5	0.3	0.4	0.9	0.7	0.7	-0.2	0.4	0.2	0.4
Whole body fat-free mass	0.2	1.3	4.6	-0.2	0.1	0.3	-2.1	-2.0	-1.2	-0.6	-1.0	-1.1	-0.4
Mood swings	0.2	0.4	2.4	0.9	-0.3	-1.5	-0.4	-0.2	-0.1	0.3	-0.3	-0.1	-0.8
Ever had bowel cancer screening	0.2	0.2	0.6	0.2	0.3	0.8	0.4	0.1	0.1	-0.6	0.6	0.4	0.2
Whole body water mass	0.2	1.2	4.4	-0.3	0.1	0.3	-2.1	-2.0	-1.2	-0.5	-0.9	-1.0	-0.3
Hearing aid user	0.2	0.2	0.8	0.6	-0.3	-0.9	-0.3	0.1	0.5	-0.6	-0.3	-0.1	-0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.8	-0.1	0.1	0.6	0.5	-0.9	0.3	-0.4	-0.3	-0.6	0.0
Basal metabolic rate	0.2	1.2	4.6	-0.0	0.1	0.1	-2.1	-1.9	-1.2	-0.6	-0.9	-1.0	-0.4
Leg fat percentage (left)	0.2	0.7	2.0	-0.2	0.4	-1.4	0.5	1.1	1.0	1.1	0.4	0.8	0.6
Irritability	0.2	0.3	1.2	-0.8	-0.3	-0.4	-0.2	-0.3	-0.6	1.1	-0.3	-0.2	-0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.0	0.3	0.4	-0.5	-0.3	0.6	1.0	0.2	0.4	0.6	-0.2
Impedance of whole body	0.2	1.1	4.2	1.1	-1.0	0.4	1.5	-0.1	0.1	-2.1	-0.8	-0.8	-0.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.6	0.9	0.7	1.3	0.1	-0.1	-0.4	-0.3	0.6	0.3	0.7
Irritable Bowel Disease (IBD)	0.1	0.3	1.5	0.3	-0.1	1.2	-0.1	-0.9	-0.3	-0.5	-0.3	-0.2	-0.2
Coronary Artery Disease (CAD)	0.1	0.1	0.5	0.1	-0.4	-0.5	0.0	-0.2	-0.7	0.1	-0.2	-0.2	-0.2
Neuroticism (2016)	0.1	0.2	0.4	0.6	-0.4	-0.6	-0.2	-0.5	-0.6	0.5	-0.0	-0.1	-0.5
Schizophrenia (2014)	0.1	0.2	0.8	-0.3	0.6	0.1	0.2	0.8	0.9	0.0	0.1	-0.1	0.4
Blood Platelet Count	0.1	0.7	3.2	0.4	0.3	-1.8	0.4	1.4	0.4	-0.5	0.3	-0.0	0.8
BMI	0.1	0.6	1.9	-0.7	0.9	-0.6	-1.1	0.3	0.4	1.4	0.4	0.6	0.6
Systolic Blood Pressure	0.1	0.7	1.8	1.3	-0.0	-1.2	0.6	1.3	0.1	0.7	0.4	0.8	0.5
Tanning	0.1	0.8	1.8	-0.8	0.6	-0.0	0.9	1.1	0.7	1.3	1.0	0.8	0.9
Hand grip strength (left)	0.1	0.3	2.4	-1.6	-0.0	-0.5	0.1	0.3	0.2	-0.3	0.0	0.0	-0.3
Hand grip strength (right)	0.1	0.2	0.8	-0.9	-0.0	-0.7	-0.6	0.1	-0.3	0.0	0.1	-0.1	-0.2
Current tobacco smoking	0.1	0.2	0.6	0.3	-0.6	-0.0	-0.6	-0.3	-0.2	-0.2	-0.5	-0.8	-0.4
Fed-up feelings	0.1	0.1	0.5	0.1	-0.1	-0.4	-0.7	-0.5	-0.1	0.5	-0.2	-0.3	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.0	0.5	0.2	-0.4	0.1	0.4	0.3	0.4	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.8	-0.7	0.1	-0.4	0.9	0.7	-0.0	0.1	0.4	0.5	0.2
Supplements: Glucosamine	0.1	0.2	0.6	0.8	0.0	0.0	-0.5	-0.3	0.4	0.1	0.1	0.2	-0.6
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.7	-0.7	0.1	-0.2	-0.2	0.1	-0.3	0.9	0.1	0.4	0.1
Body mass index (BMI)	0.1	0.5	1.7	0.2	0.4	-1.3	-1.0	0.3	0.0	1.2	0.3	0.4	0.3
Waist circumference	0.1	0.5	1.2	0.9	0.5	-1.1	-0.5	0.6	0.4	1.1	0.3	0.6	0.5
Qualifications: None of the above	0.1	0.3	1.8	-1.4	-0.2	-0.5	-0.0	0.1	-0.3	0.7	0.0	0.2	-0.0
Heart attack	0.1	0.2	0.6	0.4	0.2	-0.6	-0.4	0.2	0.8	0.1	0.1	0.3	-0.4
Neuroticism score	0.1	0.2	0.7	0.6	-0.3	-0.8	-0.5	-0.2	-0.4	0.6	-0.1	-0.1	-0.6
Weight	0.1	0.4	1.3	0.2	0.2	-0.0	-1.1	-1.1	-0.5	-0.3	-0.6	-0.5	0.0
Arm fat percentage (right)	0.1	0.4	2.2	0.8	-0.3	-1.5	-0.9	-0.1	-0.3	0.1	-0.3	-0.2	-0.2
Worrier / anxious feelings	0.1	0.1	0.4	0.2	0.2	-0.1	0.2	0.0	0.3	0.6	0.3	0.5	0.1
Falls in the last year	0.1	0.1	0.3	-0.4	-0.3	-0.5	0.6	0.0	0.3	0.2	-0.3	-0.1	-0.3
Happiness	0.1	0.2	0.6	0.8	-0.5	-0.5	-0.4	-0.3	-0.3	-0.1	-0.2	0.2	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	-0.4	0.3	0.3	-0.6	-0.3	-0.1	-0.7	0.1	-0.4	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	-0.8	-0.1	-0.2	-0.2	0.2	0.5	0.4	0.3	0.5	0.0
Prospective memory result	0.1	0.1	0.5	0.2	-0.2	-0.3	0.4	0.3	0.7	-0.2	-0.1	0.2	-0.0
Arm fat mass (right)	0.1	0.4	1.7	0.7	0.1	-1.0	-1.3	-0.4	-0.3	0.2	-0.3	-0.2	0.0
Loud music exposure frequency	0.1	0.2	0.9	1.0	0.2	0.1	-0.3	-0.2	0.3	0.1	-0.2	-0.5	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.9	0.8	0.5	0.4	0.1	0.2	0.1	1.0	0.7	0.2	0.5
Body fat percentage	0.1	0.2	1.1	0.7	0.1	-1.0	-0.0	0.6	0.3	0.3	0.0	0.2	0.4
Arm fat-free mass (right)	0.1	0.5	1.8	-0.3	0.3	0.3	-1.4	-1.2	-0.6	-0.1	-0.5	-0.6	-0.0
Neck or shoulder pain in last month	0.1	0.2	0.9	0.5	-0.3	-0.9	0.3	0.2	-0.1	-0.8	0.0	0.0	-0.5
Whole body fat mass	0.1	0.2	0.7	0.9	0.3	-0.8	-0.8	0.0	0.0	0.2	-0.1	0.1	0.3
Leg fat mass (right)	0.1	0.4	1.0	0.4	0.6	-1.0	-0.3	0.6	0.6	0.9	0.3	0.5	0.8
Arm predicted mass (right)	0.1	0.5	2.1	-0.3	0.3	0.1	-1.5	-1.1	-0.8	-0.2	-0.5	-0.6	-0.0
Leg pain on walking	0.1	0.2	0.7	-0.8	0.1	-0.4	0.5	0.4	-0.1	0.6	0.0	0.2	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.0	0.2	0.0	0.4	-0.1	0.6	-0.1	-0.1	-0.4	-0.4
Arm fat percentage (left)	0.1	0.3	1.3	0.6	0.1	-1.1	-0.8	0.2	-0.0	0.4	-0.0	0.0	0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.5	0.5	0.2	0.4	0.0	0.4	0.4	0.4	0.1	0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.4	0.0	0.3	-0.6	-0.4	-0.1	-0.0	0.1	0.1	0.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.2	0.2	-0.1	0.1	0.8	0.7	0.4	0.6	0.1	0.0
Arm fat mass (left)	0.1	0.3	1.5	0.6	0.2	-1.0	-1.2	-0.1	-0.2	0.3	-0.2	-0.0	0.2
Arm fat-free mass (left)	0.1	0.4	1.7	-0.5	0.2	-0.2	-1.3	-1.1	-0.6	-0.0	-0.5	-0.5	-0.1
Risk taking	0.1	0.2	0.8	-0.4	0.4	0.9	-0.4	0.1	-0.5	-0.6	-0.1	-0.3	0.0
Diastolic blood pressure, automated reading	0.1	0.3	0.8	0.8	-0.9	-0.2	0.6	-0.2	0.4	0.7	-0.5	0.0	-0.4
Ever depressed for a whole week	0.1	0.1	0.4	-0.0	-0.1	-0.2	-0.6	-0.3	-0.3	-0.6	0.1	-0.1	-0.5
Leg fat mass (left)	0.1	0.3	1.2	0.3	0.4	-1.1	-0.4	0.3	0.4	0.7	0.1	0.3	0.5
Arm predicted mass (left)	0.1	0.5	2.0	-0.5	0.1	-0.2	-1.4	-1.3	-0.7	-0.2	-0.7	-0.7	-0.2
Lung FVC	0.0	0.2	0.5	0.3	0.2	0.6	0.2	0.6	0.6	0.4	0.7	0.3	0.1
Hair Pigment	0.0	0.6	3.0	-1.4	-0.3	-0.4	-0.8	-0.3	-0.1	-1.7	-0.0	-0.0	-0.7
Trunk fat percentage	0.0	0.1	0.9	0.9	0.1	-0.5	-0.2	0.3	0.1	-0.2	-0.1	0.0	0.3
Trunk fat mass	0.0	0.1	0.7	0.8	0.4	-0.2	-0.5	0.0	0.1	-0.1	-0.1	-0.0	0.5
Hip circumference	0.0	0.1	0.5	0.2	0.2	-0.7	-0.6	-0.4	-0.1	-0.0	-0.2	0.1	0.1
Eye problems/disorders: None of the above	0.0	0.0	0.1	-0.1	0.1	0.2	-0.2	0.1	0.0	-0.0	-0.3	-0.4	0.2

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