TWAS hub - ATRIP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0550	0.0330	9.2e-03	0.063	NA	0.073	NA	0.068	7.4e-06	NA	1.3e-06	NA	3.3e-06
2	GTEx	Esophagus Muscularis	0.1660	0.0640	1.1e-04	0.078	NA	0.049	NA	0.072	1.7e-05	NA	6.0e-04	NA	3.5e-05
3	GTEx	Skin Not Sun Exposed Suprapubic	0.2050	0.0870	1.5e-03	0.108	NA	0.058	NA	0.054	1.6e-06	NA	4.1e-04	NA	6.1e-04
4	GTEx	Skin Sun Exposed Lower leg	0.1960	0.0670	9.9e-07	0.141	NA	0.131	NA	0.143	9.6e-12	NA	5.7e-11	NA	6.8e-12
5	ROSMAP	Brain Pre-frontal Cortex	0.2855	0.0638	1.0e-15	0.177	0.150	0.172	0.170	0.178	3.9e-22	8.3e-19	1.3e-21	2.6e-21	2.6e-22
6	YFS	Blood	0.0803	0.0257	7.4e-15	0.043	0.044	0.051	0.043	0.054	5.3e-14	4.2e-14	2.9e-16	5.0e-14	3.2e-17
7	TCGA	Breast Invasive Carcinoma	0.0279	0.0173	3.7e-06	0.030	0.032	0.030	NA	0.030	8.1e-07	3.7e-07	6.7e-07	NA	6.7e-07
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0596	0.0456	2.1e-03	0.030	0.020	0.018	NA	0.023	2.6e-04	2.4e-03	3.3e-03	NA	1.0e-03
9	TCGA	Brain Lower Grade Glioma	0.1278	0.0608	2.4e-06	0.066	0.056	0.069	NA	0.069	5.1e-08	6.1e-07	3.0e-08	NA	2.8e-08
10	TCGA	Liver Hepatocellular Carcinoma	0.0650	0.0540	7.3e-03	0.018	0.038	0.041	NA	0.034	4.8e-02	7.1e-03	5.1e-03	NA	9.6e-03
11	TCGA	Lung Adenocarcinoma	0.1039	0.0603	9.1e-04	0.029	0.007	0.015	NA	0.016	2.3e-04	4.6e-02	6.8e-03	NA	4.4e-03
12	TCGA	Lung Squamous Cell Carcinoma	0.0540	0.0342	1.1e-04	0.015	0.029	0.037	NA	0.035	6.9e-03	2.7e-04	4.6e-05	NA	6.7e-05
13	TCGA	Pheochromocytoma and Paraganglioma	0.1730	0.0900	9.3e-05	0.057	0.097	0.102	NA	0.098	2.8e-03	1.1e-04	7.4e-05	NA	1.1e-04
14	TCGA	Prostate Adenocarcinoma	0.2783	0.0812	6.1e-14	0.179	0.143	0.157	NA	0.172	2.4e-18	8.5e-15	3.8e-16	NA	1.2e-17
15	TCGA	Thyroid Carcinoma	0.0630	0.0350	5.9e-07	0.036	0.056	0.042	NA	0.046	1.7e-04	3.9e-06	6.0e-05	NA	2.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Friendships satisfaction	8.0	9.9	13.5	-2.5	-2.3	-3.0	-3.1	-3.1	-3.3	-3.6	-3.2	-3.1	-3.3	-2.9	-3.7	-3.5	-2.6	-3.7
Family relationship satisfaction	7.5	9.3	12.8	-3.2	-2.2	-2.6	-3.1	-3.1	-3.4	-3.2	-3.2	-3.1	-3.3	-2.9	-3.6	-2.7	-2.7	-3.1
Primary Biliary Cirrhosis	6.1	8.7	12.5	3.5	3.2	3.3	2.9	3.3	2.9	2.5	2.7	2.9	2.5	2.9	3.0	3.2	2.8	2.4
Pulse rate, automated reading	5.2	16.7	43.2	-5.6	-6.6	-5.7	-4.1	-4.8	-2.1	-0.8	-3.6	-4.1	-2.6	-4.8	-2.6	-1.7	-5.2	0.2
Mean Putamen Volume	5.0	5.7	7.8	2.2	1.8	2.3	2.5	2.2	2.8	2.5	2.4	2.4	2.5	2.3	2.8	2.5	2.1	2.4
Heel T-Score	5.0	39.7	80.8	-8.3	-9.0	-7.3	-6.5	-7.5	-4.5	-3.2	-6.1	-6.5	-5.2	-7.0	-5.0	-4.8	-7.3	-2.5
Major Depression (MDD)	4.9	6.0	8.3	-2.3	-1.7	-1.6	-2.8	-2.6	-2.7	-2.0	-2.9	-2.8	-2.9	-2.7	-2.6	-2.2	-2.6	-1.9
Sitting height	4.3	30.2	47.0	-5.5	-6.7	-6.9	-5.7	-6.0	-4.6	-4.4	-5.5	-5.7	-5.1	-5.9	-5.2	-4.7	-5.9	-3.6
Health satisfaction	4.3	5.6	9.9	-3.2	-2.4	-1.6	-2.6	-2.7	-2.4	-1.5	-2.5	-2.6	-2.3	-2.6	-2.3	-2.3	-2.6	-1.6
Chronotype (morning person)	4.2	9.8	16.2	-3.5	-4.0	-3.1	-3.1	-3.8	-2.9	-2.6	-3.1	-3.1	-2.9	-3.1	-2.8	-3.1	-3.0	-2.4
Eye problems/disorders: Glaucoma	4.2	4.9	9.0	-2.0	-2.5	-1.9	-2.6	-2.7	-1.8	-0.8	-2.4	-2.6	-2.1	-2.9	-1.9	-1.9	-3.0	-0.7
Type 2 Diabetes (T2D) (2012)	4.0	4.7	6.2	-2.2	-1.9	-2.4	-2.4	-2.2	-2.5	-2.2	-2.2	-2.3	-2.2	-2.2	-2.3	-2.1	0.0	-2.0
Hearing difficulty/problems with background noise	3.9	6.3	9.1	-2.4	-2.5	-2.8	-2.7	-3.0	-2.0	-1.8	-2.7	-2.7	-2.5	-2.8	-2.6	-2.2	-2.8	-1.7
Multivitamins +/- minerals	3.7	4.8	6.8	2.3	2.5	2.4	2.4	2.6	2.0	1.5	2.1	2.4	1.7	2.5	2.0	2.1	2.5	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.6	4.3	5.7	-2.4	-2.0	-1.4	-2.4	-2.2	-2.3	-1.6	-2.2	-2.3	-2.0	-2.3	-2.0	-1.8	-2.2	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	7.3	-1.4	-1.9	-2.7	-2.2	-2.1	-1.9	-1.8	-2.2	-2.2	-2.2	-2.2	-2.0	-1.6	-2.2	-1.6
Depression (self-reported)	3.4	4.1	7.0	2.2	2.6	2.4	2.1	2.2	1.7	1.4	2.0	2.1	1.8	2.2	1.6	1.9	2.3	1.1
Bipolar Disorder (2011)	3.3	3.2	9.3	3.0	2.9	2.4	2.2	0.0	1.7	1.1	0.0	2.0	0.0	2.1	1.5	1.8	0.0	0.9
Heel bone mineral density (BMD) T-score, automated (right)	3.3	7.6	18.9	-3.4	-4.4	-3.1	-2.9	-3.1	-1.7	-1.3	-2.7	-2.9	-2.2	-3.2	-1.9	-2.4	-3.4	-0.9
Miserableness	3.2	5.5	9.0	-2.9	-1.0	-0.6	-2.6	-2.2	-3.0	-2.2	-2.7	-2.5	-2.9	-2.2	-2.7	-2.0	-2.0	-2.2
Financial situation satisfaction	3.2	4.0	7.1	-2.7	-1.7	-1.1	-2.2	-2.0	-2.2	-1.7	-2.2	-2.2	-2.2	-2.1	-2.1	-1.6	-2.0	-1.6
Blood White Count	3.0	22.5	44.9	-6.7	-4.7	-3.8	-5.2	-5.6	-5.1	-3.5	-4.9	-5.2	-4.7	-5.1	-4.9	-2.4	-5.0	-2.7
Arm fat-free mass (left)	3.0	15.1	18.5	-4.3	-4.1	-2.7	-4.3	-4.3	-4.0	-3.2	-4.1	-4.3	-3.9	-4.2	-3.9	-3.6	-4.1	-2.9
Comparative body size at age 10	2.9	8.1	13.5	2.3	2.4	3.7	3.0	3.1	2.9	2.5	2.9	3.0	2.7	3.1	2.8	2.7	3.0	2.2
Arm predicted mass (right)	2.9	14.6	18.5	-4.2	-4.2	-2.9	-4.3	-4.3	-3.8	-2.9	-4.0	-4.2	-3.8	-4.2	-3.7	-3.5	-4.2	-2.6
Fasting Glucose	2.8	3.4	7.1	-1.9	-1.4	-1.2	-2.4	-1.9	-2.7	-2.0	-1.7	-1.7	-1.8	-1.5	-1.7	-2.0	0.0	-2.0
Pulse rate	2.8	4.8	15.1	-2.9	-3.9	-2.9	-2.2	-2.5	-0.7	0.3	-1.8	-2.1	-1.2	-2.7	-0.9	-0.6	-3.0	0.9
Tinnitus: Yes, but not now, but have in the past	2.7	2.9	4.0	-1.9	-1.5	-1.2	-1.9	-1.5	-1.9	-1.5	-2.0	-1.9	-2.0	-1.8	-1.8	-1.2	-1.7	-1.3
Weight	2.6	12.6	24.3	-4.9	-4.4	-2.1	-3.9	-4.0	-3.3	-2.3	-3.7	-3.9	-3.5	-3.9	-3.1	-2.7	-3.9	-1.9
Arm fat-free mass (right)	2.6	13.4	17.4	-4.2	-4.2	-2.6	-4.1	-4.1	-3.6	-2.8	-3.8	-4.0	-3.6	-4.0	-3.5	-3.4	-3.9	-2.5
Wheeze or whistling in the chest in last year	2.5	4.5	12.2	-3.5	-2.6	-1.9	-2.2	-2.9	-1.4	-0.8	-2.1	-2.2	-1.9	-2.4	-1.8	-0.7	-2.5	-0.5
Severe depression (siblings)	2.4	2.7	4.2	1.3	1.8	2.0	1.9	1.8	1.3	1.1	1.6	1.9	1.3	2.0	1.4	1.5	2.0	0.9
Standing height	2.4	23.4	54.9	-3.7	-6.6	-7.4	-4.8	-5.7	-3.1	-3.5	-4.4	-4.9	-3.8	-5.3	-4.3	-4.4	-5.5	-2.8
Height	2.3	44.5	112.4	-5.1	-9.6	-10.6	-6.7	-8.4	-3.1	-3.7	-6.2	-6.8	-4.9	-7.7	-5.6	-4.9	-8.3	-2.4
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	3.8	-1.9	-1.7	-1.8	-1.6	-1.7	-1.4	-1.3	-1.5	-1.7	-1.3	-1.7	-1.7	-1.2	-1.7	-1.1
Exposure to tobacco smoke at home	2.3	2.6	4.1	-1.6	-1.3	-0.2	-2.0	-1.7	-2.0	-1.0	-1.9	-1.9	-1.8	-1.9	-1.5	-1.4	-1.8	-0.8
Handedness (chirality/laterality): Left-handed	2.3	2.8	4.6	-1.3	-1.6	-2.1	-1.9	-1.8	-1.7	-1.2	-1.8	-1.8	-1.6	-1.9	-1.6	-1.4	-1.9	-1.2
Basal metabolic rate	2.3	12.9	17.9	-4.2	-4.2	-2.5	-4.0	-4.1	-3.5	-2.7	-3.8	-3.9	-3.5	-3.9	-3.4	-3.2	-3.9	-2.4
Vitamin and mineral supplements	2.2	2.9	5.5	-2.1	-2.3	-1.6	-1.8	-2.1	-1.5	-0.9	-1.5	-1.8	-1.2	-1.9	-1.4	-1.7	-2.0	-0.9
Whole body water mass	2.2	12.6	17.0	-3.8	-4.1	-2.7	-3.9	-4.0	-3.5	-2.8	-3.7	-3.9	-3.5	-3.9	-3.4	-3.3	-3.8	-2.5
Smoking Status	2.1	5.1	16.0	2.0	3.5	4.0	2.1	2.4	1.3	1.4	2.0	2.1	1.6	2.4	1.9	1.4	2.6	0.9
Leg fat-free mass (left)	2.1	10.9	16.2	-4.0	-3.9	-2.2	-3.6	-3.6	-3.3	-2.7	-3.5	-3.5	-3.4	-3.5	-3.1	-2.8	-3.4	-2.3
Tense / ‘highly strung’	2.1	3.5	6.9	-1.8	-0.7	-1.5	-1.8	-1.6	-2.6	-2.2	-1.9	-1.8	-2.1	-1.5	-2.4	-1.5	-1.3	-2.3
Whole body fat-free mass	2.1	12.2	16.6	-3.8	-4.1	-2.6	-3.9	-4.0	-3.4	-2.8	-3.6	-3.8	-3.4	-3.8	-3.4	-3.2	-3.8	-2.5
Leg fat-free mass (right)	2.1	11.0	16.1	-3.8	-4.0	-2.3	-3.6	-3.7	-3.2	-2.6	-3.5	-3.6	-3.4	-3.6	-3.1	-2.9	-3.5	-2.3
Diabetes diagnosed by doctor	2.1	3.4	8.4	-1.9	-2.9	-1.9	-2.0	-2.4	-1.2	-0.4	-1.7	-2.0	-1.3	-2.3	-1.1	-1.4	-2.5	-0.1
Leg predicted mass (right)	2.1	11.2	16.4	-3.9	-4.0	-2.3	-3.6	-3.7	-3.2	-2.7	-3.5	-3.6	-3.4	-3.6	-3.1	-2.9	-3.5	-2.3
Unable to work because of sickness or disability	2.1	2.8	4.6	1.1	1.7	2.2	1.8	1.5	1.5	1.4	1.9	1.8	1.9	1.8	1.8	1.3	1.8	1.1
Arm predicted mass (left)	2.1	10.8	13.9	-3.7	-3.7	-2.2	-3.7	-3.7	-3.3	-2.4	-3.4	-3.6	-3.2	-3.7	-3.1	-3.0	-3.6	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.6	12.0	-2.6	-3.5	-2.3	-2.1	-2.5	-1.2	-1.0	-2.1	-2.2	-1.7	-2.5	-1.4	-2.1	-2.6	-0.8
Trunk fat mass	2.0	8.4	20.8	-4.6	-3.6	-1.6	-3.2	-3.2	-2.7	-1.8	-3.1	-3.1	-2.9	-3.2	-2.5	-2.0	-3.1	-1.4
Father’s age at death	2.0	2.7	7.9	2.8	0.6	0.5	1.8	1.3	2.3	1.4	1.8	1.7	2.0	1.5	1.7	0.7	1.3	1.2
Qualifications: A levels/AS levels or equivalent	2.0	4.5	13.4	3.7	2.4	0.3	2.4	2.5	1.6	-0.1	2.2	2.4	1.8	2.6	1.3	1.7	2.8	-0.1
Pulse wave Arterial Stiffness index	2.0	2.3	4.9	-2.2	-1.8	-1.5	-1.7	-2.0	-1.1	-0.3	-1.4	-1.7	-1.1	-1.9	-1.3	-0.9	-2.0	-0.2
Trunk predicted mass	2.0	11.2	15.2	-3.3	-3.9	-2.8	-3.7	-3.9	-3.2	-2.6	-3.4	-3.6	-3.1	-3.7	-3.3	-3.2	-3.7	-2.4
Leg predicted mass (left)	1.9	9.9	14.9	-3.9	-3.8	-2.0	-3.4	-3.5	-3.1	-2.6	-3.3	-3.4	-3.2	-3.3	-3.0	-2.7	-3.2	-2.2
Worrier / anxious feelings	1.9	3.6	6.1	-1.9	-1.3	-1.2	-2.2	-1.8	-2.5	-1.5	-2.2	-2.2	-2.2	-2.1	-2.1	-1.4	-2.0	-1.4
Birth weight of first child	1.9	3.4	6.8	1.3	0.5	1.2	1.8	1.3	2.6	2.3	2.0	1.8	2.3	1.5	2.2	2.0	1.3	2.3
Fed-up feelings	1.8	3.2	6.3	-2.1	-0.3	0.1	-2.0	-1.5	-2.5	-1.8	-2.1	-1.9	-2.3	-1.6	-2.0	-1.6	-1.4	-1.9
Trunk fat-free mass	1.8	10.3	14.1	-3.2	-3.8	-2.7	-3.5	-3.7	-3.1	-2.5	-3.3	-3.5	-3.0	-3.5	-3.1	-3.1	-3.5	-2.3
Migraine (self-reported)	1.8	2.3	5.6	1.3	0.3	1.0	1.2	0.9	2.2	2.4	1.4	1.2	1.8	0.8	1.8	1.6	0.5	2.3
Whole body fat mass	1.8	7.4	20.7	-4.5	-3.3	-1.0	-3.0	-2.9	-2.7	-1.6	-2.9	-2.9	-2.8	-2.9	-2.3	-1.8	-2.9	-1.2
Leg fat mass (left)	1.8	7.0	20.8	-4.6	-3.0	-0.5	-3.0	-2.9	-2.6	-1.3	-2.8	-2.9	-2.6	-2.9	-2.2	-1.8	-2.9	-1.1
Hearing difficulty/problems: Yes	1.7	2.6	4.0	-1.8	-2.0	-1.8	-1.7	-1.9	-1.1	-1.1	-1.7	-1.8	-1.5	-1.8	-1.4	-1.2	-1.9	-0.9
Glaucoma (self-reported)	1.7	2.0	3.5	-1.3	-1.7	-1.2	-1.6	-1.8	-1.1	-0.5	-1.4	-1.6	-1.2	-1.8	-1.2	-1.5	-1.9	-0.5
Leg fat mass (right)	1.7	6.4	19.8	-4.5	-2.9	-0.5	-2.8	-2.8	-2.5	-1.2	-2.7	-2.8	-2.5	-2.8	-2.0	-1.6	-2.7	-0.9
Depressed Affect (Nagel 2018)	1.6	3.3	6.9	-1.6	-0.2	0.2	-1.9	-1.3	-2.6	-2.1	-2.0	-1.8	-2.2	-1.4	-2.1	-2.1	-1.2	-2.3
Medication: Metformin	1.6	2.2	6.1	-1.8	-2.5	-1.6	-1.6	-2.0	-1.0	-0.2	-1.2	-1.6	-0.8	-1.9	-1.0	-0.4	-2.0	0.2
Number of full brothers	1.6	2.0	6.2	0.8	2.1	2.5	1.4	1.5	0.6	0.9	1.3	1.4	1.0	1.7	1.1	1.1	1.8	0.6
Worry too long after embarrassment	1.6	2.6	7.5	-2.1	-2.7	-2.6	-1.5	-2.0	-0.9	-0.6	-1.3	-1.5	-1.1	-1.7	-1.1	-0.8	-1.8	-0.3
Medication: Omeprazole	1.6	2.0	4.3	0.1	1.0	1.5	1.3	1.2	1.4	1.7	1.3	1.3	1.3	1.2	1.6	2.1	1.1	1.9
Number of full sisters	1.6	2.0	3.4	0.8	1.0	1.8	1.4	1.3	1.3	1.6	1.5	1.4	1.5	1.3	1.7	1.3	1.3	1.6
Osteoporosis (self-reported)	1.6	2.0	9.0	0.1	1.1	-0.1	-0.5	-0.1	-1.7	-2.6	-1.0	-0.5	-1.6	0.0	-1.5	-1.8	0.4	-3.0
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	4.6	-1.6	-0.3	-0.2	-1.6	-1.7	-2.2	-1.6	-1.7	-1.6	-1.8	-1.3	-1.9	-1.1	-1.2	-1.6
Neuroticism score	1.5	3.1	5.7	-2.4	-1.4	-1.0	-2.0	-1.8	-2.2	-1.3	-1.9	-1.9	-1.9	-1.8	-1.8	-1.1	-1.7	-1.2
Medication: Cholesterol lowering	1.5	2.3	4.4	-1.5	-1.9	-1.2	-1.7	-2.1	-1.1	-0.3	-1.6	-1.8	-1.3	-2.0	-1.2	-1.4	-2.1	-0.1
BMI	1.4	8.0	20.2	-4.5	-2.5	0.2	-3.2	-2.8	-3.3	-1.9	-3.2	-3.1	-3.3	-2.9	-2.7	-2.0	-2.7	-1.8
Neuroticism	1.4	3.4	7.5	-2.2	-0.8	-0.7	-2.1	-1.6	-2.7	-1.7	-2.0	-2.0	-2.1	-1.8	-2.1	-1.5	-1.6	-1.7
Diabetes (mother)	1.4	1.8	3.9	-2.0	-1.9	-0.8	-1.5	-1.6	-1.5	-0.8	-1.3	-1.5	-1.2	-1.5	-1.2	-0.9	-1.5	-0.5
Number of incorrect matches in round	1.4	2.2	6.4	-1.8	0.1	-0.1	-1.1	-0.9	-2.5	-2.2	-1.4	-1.1	-1.9	-0.6	-2.0	-0.9	-0.2	-2.3
Medication for cholesterol, blood pressure or diabetes	1.4	2.3	4.5	1.9	1.9	1.1	1.7	2.1	1.2	0.2	1.5	1.7	1.2	1.9	1.0	1.2	2.0	-0.1
Mean time to correctly identify matches	1.4	2.6	9.0	2.8	3.0	1.8	1.4	2.2	0.3	0.1	1.2	1.4	0.8	1.8	0.8	0.5	2.0	-0.3
Mood swings	1.4	2.5	4.4	-1.6	-0.9	-0.2	-1.7	-1.6	-2.1	-1.5	-1.7	-1.7	-1.8	-1.5	-1.7	-1.8	-1.4	-1.7
Wears glasses or contact lenses	1.4	1.6	2.2	-0.2	-0.4	-1.3	-1.4	-1.1	-1.4	-1.3	-1.5	-1.4	-1.5	-1.4	-1.5	-1.3	-1.3	-1.2
Alzheimer’s Disease (in mother)	1.3	1.5	2.7	1.5	1.2	0.7	1.6	1.3	1.0	0.4	1.5	1.5	1.3	1.6	1.2	0.7	1.6	0.3
Lung FEV1/FVC ratio	1.3	6.8	11.2	3.0	1.4	2.0	2.5	2.1	3.3	3.2	2.6	2.5	2.9	2.1	3.1	2.2	1.8	3.3
Lung FVC	1.3	6.5	8.6	2.4	1.6	1.5	2.8	2.9	2.8	2.4	2.8	2.7	2.8	2.6	2.7	2.9	2.4	2.6
Trunk fat percentage	1.3	5.2	16.1	-4.0	-2.8	-1.2	-2.5	-2.4	-2.1	-1.3	-2.4	-2.4	-2.3	-2.4	-1.9	-1.2	-2.4	-0.9
Current tobacco smoking	1.3	2.2	9.0	0.6	2.2	3.0	1.3	1.6	0.8	1.1	1.2	1.4	0.9	1.5	1.3	1.2	1.6	0.8
Ever had bowel cancer screening	1.3	1.5	3.1	1.8	1.4	1.3	1.4	1.4	0.8	0.5	1.4	1.4	1.2	1.5	1.0	0.4	1.6	0.1
Arm fat mass (left)	1.3	5.5	16.5	-4.1	-2.7	-0.5	-2.6	-2.4	-2.4	-1.5	-2.5	-2.5	-2.5	-2.5	-2.0	-1.4	-2.4	-1.1
Alcohol drinker status: Previous	1.3	1.5	2.3	0.6	1.1	1.2	1.3	1.0	1.0	1.2	1.4	1.3	1.5	1.2	1.4	1.5	1.2	1.2
Waist Hip Ratio (WHR)	1.2	5.2	20.3	-2.5	-4.5	-4.5	-0.9	-2.5	1.5	1.8	-0.2	-0.9	0.9	-1.8	0.7	0.8	-2.4	2.6
Waist circumference	1.2	4.3	13.5	-3.7	-3.4	-1.3	-2.2	-2.6	-1.3	-0.4	-1.9	-2.1	-1.5	-2.4	-1.2	-0.8	-2.5	0.0
Alcohol intake versus 10 years previously	1.2	1.8	3.6	0.0	0.7	1.9	1.5	1.3	1.2	1.4	1.3	1.5	1.2	1.4	1.7	0.9	1.4	1.4
Arm fat mass (right)	1.2	5.1	16.3	-4.0	-2.6	-0.2	-2.5	-2.3	-2.4	-1.3	-2.4	-2.5	-2.4	-2.4	-1.9	-1.2	-2.3	-1.0
Breastfed as a baby	1.2	1.4	2.6	0.5	0.8	0.6	1.4	1.2	1.3	0.9	1.4	1.4	1.3	1.4	1.2	1.6	1.4	1.0
Smoking status: Previous	1.2	1.8	2.5	1.4	1.2	1.3	1.5	1.2	1.6	1.4	1.4	1.4	1.4	1.4	1.4	0.8	1.3	1.2
Qualifications: nursing, teaching	1.2	1.8	7.3	0.4	0.3	-1.6	-0.6	-0.2	-1.6	-2.7	-0.9	-0.5	-1.3	-0.1	-1.5	-1.3	0.2	-2.7
Pain type(s) experienced in last month: Hip pain	1.2	1.5	2.4	-1.3	-1.4	-1.4	-1.3	-1.6	-1.1	-0.9	-1.2	-1.3	-1.1	-1.3	-1.2	-1.2	-1.3	-0.8
Alcohol drinker status: Never	1.2	1.4	2.8	0.2	0.4	0.8	1.2	0.9	1.2	1.4	1.3	1.3	1.4	1.2	1.4	1.7	1.1	1.5
Verbal and Numeric Reasoning (VNR)	1.1	2.6	11.6	3.4	2.6	0.3	1.5	2.2	0.8	-0.3	1.4	1.5	1.1	1.7	0.9	-0.1	1.8	-0.6
Age at First Birth	1.1	1.6	6.5	2.6	1.8	0.7	2.2	2.4	1.4	0.2	0.4	0.3	0.5	0.2	0.2	0.2	0.0	0.2
Body Mass Index (BMI) (2010)	1.1	1.5	2.7	-1.4	-0.9	-1.1	-1.6	-1.6	-1.5	-1.2	-1.3	-1.1	-1.4	-1.0	-1.3	-0.9	0.0	-1.2
Hand grip strength (left)	1.1	2.8	4.5	-1.7	-1.8	-1.5	-1.7	-2.1	-1.3	-1.6	-1.7	-1.8	-1.6	-1.8	-1.9	-1.5	-1.8	-1.5
Supplements: Zinc	1.1	1.2	2.4	1.2	1.2	0.9	1.3	1.2	0.7	0.1	1.1	1.3	0.8	1.4	0.8	1.3	1.5	0.1
Pain all over the body in last month	1.1	1.2	5.2	0.6	2.0	2.3	0.9	1.0	-0.3	-0.2	0.8	1.0	0.4	1.3	0.5	0.6	1.5	-0.3
Falls in the last year	1.1	1.5	3.5	0.2	0.0	0.6	1.2	0.6	1.7	1.9	1.3	1.2	1.6	0.9	1.6	1.1	0.7	1.8
Body fat percentage	1.1	4.2	15.4	-3.9	-2.4	-0.4	-2.2	-2.1	-2.0	-1.1	-2.2	-2.2	-2.1	-2.1	-1.6	-1.1	-2.1	-0.8
Mouth/teeth dental problems: Loose teeth	1.1	1.3	4.6	-1.6	-1.6	-0.7	-0.1	-1.0	1.2	1.7	0.2	-0.2	0.8	-0.7	0.4	1.2	-1.0	2.1
Irritability	1.1	1.9	5.4	-0.8	0.2	0.2	-1.3	-0.8	-2.3	-1.8	-1.4	-1.3	-1.7	-0.9	-1.7	-1.5	-0.6	-2.0
Myopia	1.1	1.6	5.0	1.2	0.6	-0.4	-0.8	-0.4	-1.4	-1.9	-0.9	-0.8	-1.2	-0.5	-1.2	-2.2	-0.3	-2.2
Age when periods started (menarche)	1.0	2.4	4.6	-0.3	0.7	-0.2	-1.8	-1.1	-2.1	-1.6	-1.8	-1.7	-1.9	-1.5	-2.0	-1.8	-1.4	-1.7
Medication: Atenolol	1.0	1.3	2.8	-0.1	1.1	1.3	1.1	0.9	0.7	1.4	1.1	1.1	1.1	1.0	1.1	1.7	1.0	1.5
Medication: Levothyroxine sodium	1.0	1.7	4.0	1.4	1.9	1.9	1.4	1.8	-0.0	-0.2	1.2	1.4	0.8	1.8	0.7	0.2	2.0	-0.6
Diabetes (self-reported)	1.0	1.5	5.6	-1.5	-2.4	-1.0	-1.2	-1.6	-0.4	0.5	-0.9	-1.2	-0.5	-1.6	-0.2	-0.3	-1.8	0.9
Fluid intelligence score	1.0	2.1	8.9	3.0	2.9	0.4	1.0	1.9	-0.0	-0.9	0.9	1.0	0.6	1.4	0.2	-0.4	1.7	-1.3
Medication: Lansoprazole	1.0	1.2	1.7	-1.3	-1.0	-1.1	-1.2	-1.2	-1.2	-0.8	-1.1	-1.2	-1.0	-1.2	-0.9	-0.7	-1.2	-0.5
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.2	-1.5	-0.7	-0.1	-1.0	-1.2	-1.3	-1.3	-1.1	-1.0	-1.3	-0.8	-1.2	-1.2	-0.7	-1.3
Chronic bronchitis/emphysema (mother)	1.0	1.1	1.9	-0.1	0.3	1.1	1.1	0.5	1.2	1.3	1.2	1.1	1.4	0.9	1.4	1.0	0.8	1.2
Neuroticism (Nagel 2018)	0.9	2.1	5.3	-1.4	-0.4	-0.5	-1.4	-1.0	-2.3	-1.8	-1.5	-1.4	-1.8	-1.1	-1.7	-1.5	-0.9	-1.9
Triglycerides	0.9	1.5	3.5	0.2	-0.3	0.7	1.0	0.5	1.5	1.7	1.3	1.2	1.5	1.0	1.8	1.4	0.0	1.9
Type 2 Diabetes (T2D) (2018)	0.9	1.7	3.4	-1.4	-1.9	-1.1	-1.5	-1.6	-1.1	-0.3	-1.4	-1.5	-1.1	-1.6	-0.9	-1.0	-1.8	-0.1
Hand grip strength (right)	0.9	2.5	4.2	-1.5	-1.8	-1.5	-1.6	-2.0	-1.2	-1.6	-1.6	-1.7	-1.5	-1.7	-1.6	-1.5	-1.7	-1.4
Maternal smoking around birth	0.9	1.3	3.1	-1.8	-1.6	-1.0	-1.2	-1.5	-0.4	0.3	-1.0	-1.2	-0.7	-1.5	-0.7	-0.2	-1.6	0.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.0	0.2	1.7	1.7	1.0	1.3	-0.3	-0.7	0.8	0.9	0.3	1.4	0.3	0.6	1.7	-0.8
Loud music exposure frequency	0.9	1.0	1.7	0.6	0.8	0.8	1.1	0.9	1.1	1.1	1.0	1.1	0.9	1.0	1.3	1.1	1.0	1.1
Blood clot in the leg (DVT)	0.9	1.2	2.4	1.6	1.0	1.0	1.1	1.0	1.4	1.0	1.0	1.0	1.0	0.9	1.1	0.9	0.9	0.9
Headache pain in last month	0.9	1.5	2.2	0.9	1.3	1.1	1.2	1.2	1.5	1.3	1.3	1.2	1.3	1.1	1.1	1.2	1.1	1.1
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.3	1.5	2.1	1.9	1.4	1.7	-0.2	-0.5	1.2	1.3	0.7	1.8	0.5	-0.3	2.0	-1.0
Eye problems/disorders: None of the above	0.9	1.1	2.3	1.1	1.4	0.7	1.3	1.1	0.9	0.1	1.1	1.2	0.9	1.4	0.6	1.0	1.5	-0.0
Had major operations	0.9	1.0	2.3	-0.2	0.2	-0.1	-1.1	-0.7	-1.5	-1.3	-1.3	-1.1	-1.4	-0.9	-1.0	-1.0	-0.7	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	2.8	-1.7	-1.4	-0.5	-1.2	-1.3	-0.6	-0.0	-0.9	-1.1	-0.6	-1.3	-0.6	-0.8	-1.4	-0.0
Loneliness, isolation	0.9	1.2	2.1	-1.3	-0.3	0.2	-1.2	-1.1	-1.5	-0.9	-1.3	-1.2	-1.5	-1.0	-1.2	-1.1	-0.9	-1.0
Average weekly beer plus cider intake	0.9	1.4	3.4	-1.9	-0.9	-1.0	-1.3	-1.3	-1.2	-0.6	-1.2	-1.2	-1.2	-1.2	-1.3	-0.8	-1.2	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.5	0.5	1.0	1.1	0.9	1.0	0.9	1.1	0.9	0.9	1.0	0.9	1.1	1.6	0.8	1.3
Hypothyroidism (self reported)	0.8	1.8	6.4	0.2	0.8	0.4	-0.8	-0.1	-2.3	-2.1	-1.0	-0.8	-1.5	-0.3	-1.6	-1.9	0.1	-2.5
Angina	0.8	1.1	2.7	-1.6	-1.4	-0.6	-1.1	-1.4	-0.8	-0.3	-1.0	-1.2	-0.9	-1.2	-0.9	-0.3	-1.3	-0.0
Taking other prescription medications	0.8	1.3	3.3	-1.8	-0.4	0.1	-1.1	-1.3	-1.5	-0.9	-1.2	-1.2	-1.2	-1.1	-1.2	-1.0	-1.0	-1.0
Past tobacco smoking	0.8	1.5	2.8	-1.1	-1.6	-1.7	-1.3	-1.1	-1.3	-1.3	-1.2	-1.2	-1.2	-1.2	-1.1	-0.8	-1.2	-1.0
Illnesses of siblings	0.8	1.1	3.2	-0.8	-1.4	-1.8	-1.1	-0.9	-0.4	-0.8	-1.2	-1.1	-1.2	-1.1	-0.9	-0.4	-1.1	-0.5
Birth weight	0.8	1.7	3.8	1.8	1.2	2.0	1.4	1.6	1.2	0.5	1.3	1.3	1.1	1.5	1.1	0.4	1.6	0.3
Medication: Ibuprofen	0.8	0.9	1.6	-1.3	-0.9	-0.1	-1.1	-1.0	-0.9	-0.6	-0.9	-1.1	-0.9	-1.1	-1.0	-1.2	-1.0	-0.7
Illnesses of siblings: Diabetes	0.8	1.0	2.3	-1.1	-0.8	0.6	-0.9	-1.0	-1.4	-1.0	-0.9	-0.9	-0.9	-0.7	-0.9	-1.5	-0.6	-1.1
Medication: Bendroflumethiazide	0.8	1.2	2.8	-1.7	-1.3	-1.0	-1.1	-1.4	-1.2	-0.4	-1.1	-1.1	-1.0	-1.2	-0.9	-1.0	-1.2	-0.5
Intelligence (Savage-Jansen 2018)	0.7	2.1	14.1	3.8	1.4	-0.8	1.3	1.2	1.1	-0.5	1.2	1.2	1.1	1.3	0.7	-1.0	1.4	-0.9
Prostate Cancer	0.7	1.0	3.9	0.8	2.0	1.7	0.8	1.3	-0.0	0.3	0.5	0.9	0.2	1.0	0.5	0.8	1.2	0.1
HDL Cholesterol	0.7	1.2	2.5	1.6	1.4	0.9	1.2	1.5	1.2	0.8	1.2	1.1	1.2	1.1	0.9	0.8	0.0	0.6
Neuroticism (2016)	0.7	1.0	2.2	-1.2	-0.3	0.4	-0.9	-0.7	-1.5	-1.3	-1.0	-0.9	-1.3	-0.6	-1.1	-1.1	-0.4	-1.4
Blood Red Count	0.7	6.8	13.0	-2.6	-3.6	-2.9	-2.8	-2.7	-2.6	-2.0	-2.6	-2.7	-2.3	-2.9	-2.0	-2.5	-2.9	-1.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.5	-0.3	0.1	0.1	-0.9	-0.5	-1.5	-1.6	-1.0	-1.0	-1.1	-0.7	-1.3	-0.8	-0.5	-1.6
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.9	2.0	1.7	0.6	0.8	1.3	0.3	-0.1	0.7	0.8	0.5	1.0	0.4	-0.2	1.1	-0.5
Pack years adult smoking proportion	0.7	1.1	3.6	-0.7	1.1	1.5	-0.7	-0.0	-1.9	-1.5	-0.8	-0.7	-1.2	-0.3	-1.1	-0.7	0.0	-1.6
Average weekly fortified wine intake	0.7	0.8	1.5	-0.5	-0.4	-0.9	-0.9	-0.8	-0.8	-1.1	-0.9	-0.9	-0.9	-0.9	-1.0	-1.2	-0.8	-1.1
Qualifications: CSEs or equivalent	0.7	0.9	1.7	-0.7	-0.5	-0.0	-1.1	-1.0	-1.2	-0.7	-1.0	-1.0	-1.0	-1.0	-0.9	-1.3	-1.0	-0.9
High blood pressure (mother)	0.7	0.9	1.5	0.8	0.6	0.9	1.1	0.8	0.8	0.8	1.2	1.1	1.2	1.1	0.8	0.9	1.1	0.8
Body mass index (BMI)	0.7	3.1	12.4	-3.5	-1.6	1.1	-1.9	-1.7	-2.0	-0.7	-1.9	-1.9	-1.9	-1.8	-1.3	-0.8	-1.6	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	4.0	1.0	2.0	2.0	0.9	1.2	-0.1	-0.2	0.8	1.0	0.4	1.3	0.6	0.4	1.5	-0.4
Angina (self-reported)	0.7	0.9	2.5	-1.6	-1.3	-0.5	-1.0	-1.3	-0.8	-0.2	-1.0	-1.1	-0.9	-1.1	-0.8	-0.2	-1.2	0.0
Knee pain experienced in last month	0.7	1.2	5.0	-0.7	-0.7	0.0	0.3	-0.4	1.3	2.2	0.6	0.4	1.0	-0.1	1.0	1.3	-0.4	2.2
Commuting to job workplace: Walk	0.7	0.7	2.1	0.5	0.8	0.4	0.6	0.9	-0.8	-1.5	0.5	0.7	0.0	1.1	0.1	-0.2	1.4	-1.4
Ever smoked	0.7	1.3	4.1	1.1	2.0	2.0	1.0	1.3	0.8	0.8	0.9	1.0	0.7	1.2	0.7	0.5	1.2	0.4
Leg fat percentage (left)	0.7	2.7	12.8	-3.6	-1.7	0.7	-1.8	-1.7	-1.6	-0.4	-1.6	-1.7	-1.5	-1.7	-1.1	-1.0	-1.7	-0.3
Alzheimer’s Disease (including proxy)	0.6	0.8	1.6	0.8	0.6	0.1	1.1	0.6	1.1	0.8	1.2	1.0	1.3	1.0	0.9	0.8	0.9	0.8
Ulcerative Colitis (UC)	0.6	1.0	3.4	1.7	-1.5	-1.2	0.8	-0.2	1.8	1.2	0.4	0.3	1.0	-0.3	0.9	-0.5	0.0	1.1
Breast Cancer	0.6	1.6	2.4	1.4	0.7	1.1	1.4	1.0	1.3	1.0	1.6	1.5	1.6	1.4	1.3	0.9	1.4	0.8
Crohns Disease (2012)	0.6	0.9	5.6	2.4	1.1	0.2	0.8	0.7	0.2	-1.0	0.0	0.2	-0.2	0.3	-0.4	-1.6	0.0	-1.4
Ulcerative Colitis	0.6	0.9	4.9	2.2	-0.4	0.0	1.2	0.6	1.7	1.0	0.6	0.6	0.8	0.3	1.0	-0.1	0.0	1.0
Number of treatments/medications taken	0.6	1.1	4.0	-2.0	-0.6	-0.0	-1.1	-1.2	-1.3	-0.4	-1.1	-1.1	-1.0	-1.1	-1.0	-0.4	-1.0	-0.3
Diabetes (father)	0.6	0.8	2.5	-0.1	-0.4	0.3	0.6	0.3	0.9	1.5	0.8	0.7	1.1	0.4	1.2	1.2	0.2	1.6
Hip circumference	0.6	2.5	5.3	-2.3	-1.2	0.4	-1.8	-1.4	-2.0	-1.4	-1.8	-1.7	-1.9	-1.5	-1.6	-1.3	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.1	4.6	1.6	-0.3	-0.1	1.6	1.1	2.1	1.4	1.6	1.5	1.9	1.2	1.8	1.0	1.0	1.6
Pulse wave peak to peak time	0.6	0.8	2.4	1.6	1.0	0.7	0.9	1.2	0.4	-0.4	0.7	0.9	0.5	1.1	0.6	0.2	1.2	-0.4
Qualifications: College or University degree	0.6	1.9	6.9	1.9	-0.6	-2.6	-0.4	-0.7	-0.9	-2.4	-0.6	-0.4	-0.7	-0.3	-1.1	-1.8	-0.1	-2.4
Comparative height size at age 10	0.6	3.2	10.6	-1.4	-2.6	-3.2	-1.7	-1.9	-1.0	-1.6	-1.5	-1.7	-1.3	-1.8	-1.5	-1.4	-1.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.1	-0.4	-1.1	-1.8	-1.2	-1.1	-0.7	-1.0	-1.0	-1.2	-0.8	-1.3	-1.1	-1.2	-1.3	-0.8
Arm fat percentage (left)	0.6	2.4	11.3	-3.4	-1.7	0.6	-1.6	-1.3	-1.7	-0.9	-1.6	-1.5	-1.7	-1.4	-1.1	-0.6	-1.3	-0.6
Guilty feelings	0.6	1.0	2.6	0.1	0.5	1.6	1.1	0.8	0.9	0.8	1.1	1.0	1.0	1.1	1.2	0.9	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.0	0.2	-0.4	0.4	0.7	0.2	1.1	1.3	0.8	0.7	0.9	0.5	1.2	0.8	0.3	1.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.1	1.4	0.9	1.0	0.9	0.8	1.0	0.6	0.8	0.9	0.8	0.8	0.9	0.5	0.8	0.4
Bipolar Disorder (2018)	0.5	0.7	1.9	1.3	1.3	1.4	0.9	0.9	0.2	-0.3	0.6	0.8	0.3	1.1	0.2	0.4	1.2	-0.4
Schizophrenia vs Biploar Disorder	0.5	0.7	1.3	-0.8	-1.1	-1.0	-0.9	-1.0	-0.7	-0.5	-1.0	-0.9	-0.9	-1.0	-0.6	-0.9	0.0	-0.4
Crohns Disease (2017)	0.5	1.0	6.0	2.4	0.5	-1.0	0.8	0.5	0.6	-0.9	-0.6	-0.5	-0.5	-0.6	-0.7	-1.8	0.0	-1.3
Reaction Time	0.5	1.0	4.2	1.8	2.0	0.9	0.7	1.2	-0.3	-0.5	0.6	0.8	0.2	1.1	0.1	-0.3	1.3	-0.8
Coronary Artery Disease (CAD)	0.5	0.6	1.7	-1.3	-1.3	-0.6	-1.0	-1.2	-0.8	-0.4	-0.6	-0.5	-0.5	-0.6	-0.4	-0.8	0.0	-0.4
HbA1C	0.5	0.6	2.3	-0.6	-1.5	-1.3	-0.9	-0.9	-0.2	0.2	-0.3	-0.7	0.4	-1.1	-0.1	0.5	0.0	0.4
Lupus	0.5	0.7	2.2	1.5	0.8	1.4	0.7	1.0	0.7	0.5	0.7	0.7	0.6	0.6	1.0	0.4	0.6	0.6
Rheumatoid Arthritis	0.5	0.7	1.3	1.1	0.8	1.1	0.8	1.1	0.7	0.6	0.8	0.9	0.8	0.9	0.8	0.1	0.9	0.3
Qualifications: None of the above	0.5	1.0	6.4	-0.7	0.7	2.5	0.6	0.7	0.5	1.3	0.5	0.5	0.4	0.6	0.9	1.0	0.6	1.4
Arm fat percentage (right)	0.5	2.0	9.4	-3.1	-1.4	0.9	-1.4	-1.1	-1.6	-0.8	-1.5	-1.4	-1.6	-1.3	-1.0	-0.5	-1.1	-0.6
Hair/balding pattern: Pattern 3	0.5	0.7	1.4	1.2	1.1	0.9	0.8	1.0	1.0	0.9	0.6	0.7	0.7	0.6	0.9	0.6	0.6	0.8
Peak expiratory flow (PEF)	0.5	1.3	3.9	2.0	0.4	1.2	1.0	1.2	1.2	1.0	1.2	1.0	1.4	0.9	1.3	0.4	0.8	0.9
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.4	1.9	0.6	-0.4	1.0	0.8	0.7	-0.2	1.0	1.0	0.9	1.1	0.5	0.0	1.1	-0.5
Leg fat percentage (right)	0.5	1.9	10.8	-3.3	-1.3	0.9	-1.4	-1.3	-1.4	-0.2	-1.3	-1.4	-1.2	-1.3	-0.8	-0.6	-1.3	-0.1
Neck or shoulder pain in last month	0.5	0.7	1.2	-1.0	-0.4	-0.5	-1.0	-0.9	-0.7	-0.1	-0.9	-1.0	-0.8	-1.1	-0.8	-0.6	-1.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.6	0.6	-0.2	0.8	0.4	0.4	1.1	1.6	0.5	0.4	0.7	0.1	1.2	0.2	-0.1	1.4
Alcohol intake frequency.	0.5	1.2	2.4	-0.0	0.1	1.2	1.1	0.7	0.9	1.2	1.3	1.2	1.3	1.1	1.6	1.0	1.0	1.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.4	-0.4	-0.6	-0.1	-0.4	-0.5	0.8	1.5	-0.3	-0.4	0.1	-0.8	0.2	0.8	-1.0	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.7	-0.2	-0.4	0.6	0.5	0.5	1.1	1.3	0.6	0.4	0.8	0.2	1.1	0.5	0.1	1.3
Smoking status: Current	0.5	0.8	5.2	0.1	1.6	2.3	0.7	0.9	0.2	0.6	0.5	0.7	0.3	0.8	0.7	0.6	0.9	0.3
Number of self-reported non-cancer illnesses	0.5	0.8	2.8	0.9	1.2	1.7	0.9	0.9	0.3	0.3	0.9	0.9	0.7	1.0	0.7	0.0	1.1	0.1
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.4	0.8	0.5	0.5	0.9	0.7	1.2	1.1	0.8	0.7	0.9	0.6	0.7	1.2	0.5	1.2
Medication: Paracetamol	0.5	0.7	2.8	-0.3	1.7	1.1	-0.2	0.4	-1.1	-1.1	-0.4	-0.2	-0.7	0.2	-0.8	-0.4	0.5	-1.5
Supplements: Calcium	0.5	0.6	1.1	0.8	1.0	0.9	1.0	0.8	0.7	0.3	0.7	0.9	0.5	1.0	0.5	0.6	1.1	0.2
Pack years of smoking	0.5	0.7	2.1	-0.3	1.0	1.4	-0.4	0.1	-1.5	-1.1	-0.5	-0.4	-0.8	-0.1	-0.7	-0.4	0.2	-1.2
Depression (Nagel 2018)	0.4	0.6	2.2	0.5	0.6	0.4	-0.5	-0.1	-1.1	-1.4	-0.4	-0.4	-0.6	-0.1	-0.8	-0.9	0.1	-1.5
Irritable Bowel Disease (IBD)	0.4	1.0	6.8	2.6	-0.8	-1.3	1.0	0.1	1.5	0.1	-0.2	-0.2	0.2	-0.6	0.0	-1.4	0.0	-0.2
LDL Cholesterol	0.4	0.7	1.5	0.6	0.1	1.2	0.8	0.7	0.8	0.8	1.0	0.9	1.0	0.9	1.2	0.5	0.0	0.8
Cardiovascular Disease	0.4	1.2	2.7	-1.4	-1.3	-0.2	-1.1	-1.4	-1.7	-0.5	-1.0	-1.1	-0.9	-1.1	-0.9	-1.4	-1.1	-0.6
Serious illness, injury or assault to yourself	0.4	0.4	2.3	0.2	-0.3	0.3	-0.4	-0.5	-0.8	-0.9	-0.3	-0.4	-0.3	-0.3	-0.5	-1.5	-0.2	-1.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.0	-0.1	0.4	0.1	-0.7	-0.6	-0.9	-0.9	-0.9	-0.8	-1.0	-0.6	-1.0	-0.7	-0.5	-1.0
Financial difficulties in last 2 years	0.4	0.5	1.9	-1.4	-1.0	-0.0	-0.7	-1.0	-0.1	0.4	-0.6	-0.7	-0.4	-0.9	-0.1	-0.2	-1.0	0.5
Happiness	0.4	0.4	1.2	-0.4	-0.2	-0.4	-0.7	-0.7	-0.8	-0.7	-0.6	-0.7	-0.6	-0.6	-1.1	-0.4	-0.6	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	-1.1	-0.8	-0.1	-0.8	-0.9	-0.7	-0.4	-0.6	-0.8	-0.5	-0.8	-0.7	-0.9	-0.8	-0.4
Lung cancer (father)	0.4	0.5	3.7	0.1	1.0	1.9	0.3	0.7	-0.5	-0.4	0.1	0.3	-0.2	0.6	-0.1	-0.6	0.8	-0.8
High blood pressure (siblings)	0.4	0.6	1.3	0.6	1.0	0.6	0.8	0.7	0.5	0.8	1.0	0.9	1.1	0.8	0.8	0.6	0.8	0.8
Emphysema/chronic bronchitis	0.4	0.4	1.2	-0.3	0.1	0.6	0.4	0.4	0.8	1.1	0.5	0.5	0.5	0.3	0.7	0.9	0.3	1.0
Age at last live birth	0.4	0.5	3.0	1.7	0.5	-0.9	0.3	0.5	-0.1	-1.0	0.3	0.4	0.1	0.5	-0.2	-0.5	0.6	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.1	-1.4	-1.3	-0.7	-0.5	-0.9	0.1	0.2	-0.5	-0.4	-0.3	-0.6	-0.2	-0.4	-0.8	0.2
Back pain experienced in last month	0.4	0.7	2.0	-0.8	-0.4	0.9	0.6	0.3	0.9	1.4	0.8	0.7	1.0	0.5	1.0	0.1	0.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.6	1.1	0.4	0.5	0.9	1.0	1.2	1.1	0.9	0.9	1.0	0.8	1.2	1.0	0.6	1.3
Mother’s age at death	0.4	0.5	0.8	0.7	0.4	-0.3	0.8	0.7	0.9	0.7	0.8	0.9	0.9	0.8	0.7	0.8	0.7	0.7
Medication: Lisinopril	0.4	0.5	0.9	0.6	0.6	0.5	0.9	0.6	0.3	0.2	0.8	0.9	0.7	0.9	0.9	0.5	0.9	0.3
Ever depressed for a whole week	0.4	0.5	3.5	0.8	1.9	1.0	0.5	0.6	0.1	-0.0	0.3	0.5	0.1	0.7	0.0	0.9	0.8	-0.0
Worry (Nagel 2018)	0.3	0.7	1.6	-1.1	-0.5	-0.9	-0.9	-0.9	-1.3	-0.7	-0.7	-0.9	-0.7	-0.8	-1.1	-0.5	-0.7	-0.7
Alzheimer’s Disease (in father)	0.3	0.4	1.3	0.5	0.2	0.4	0.3	0.2	0.8	1.1	0.5	0.3	0.7	0.1	0.7	0.6	-0.0	1.2
Ovarian Cancer	0.3	0.4	2.0	0.6	1.4	0.9	0.5	0.7	0.1	0.2	0.4	0.5	0.3	0.6	0.1	0.6	0.6	-0.0
Blood Eosinophil Count	0.3	2.5	17.8	-2.1	-4.2	-2.6	-0.2	-1.9	1.0	0.0	-0.0	-0.3	0.5	-0.7	0.6	0.5	-1.0	1.0
Average weekly spirits intake	0.3	0.3	1.1	-0.9	0.2	1.0	0.4	0.5	0.5	0.5	0.3	0.3	0.2	0.4	0.5	0.9	0.4	0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.5	-0.5	-0.6	0.1	0.3	-0.1	0.8	1.2	0.4	0.3	0.7	0.1	0.8	0.3	-0.1	1.2
Hair/balding pattern: Pattern 2	0.3	0.3	1.0	-0.9	-0.9	-0.3	0.1	-0.7	0.6	0.8	0.2	0.1	0.4	-0.1	0.4	0.5	-0.2	1.0
Heart attack	0.3	0.4	1.1	-0.5	-0.1	0.6	-0.7	-0.5	-1.0	-0.4	-0.7	-0.7	-0.7	-0.6	-0.5	-0.5	-0.5	-0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.9	0.6	0.8	0.9	0.7	0.8	0.4	-0.0	0.5	0.7	0.3	0.8	0.4	-0.0	0.9	-0.1
Time employed in main current job	0.3	0.3	1.0	0.8	0.4	1.0	0.5	0.4	0.3	0.2	0.5	0.5	0.5	0.5	0.6	-0.7	0.5	-0.1
Number of live births	0.3	0.5	1.5	-1.2	-0.6	-0.6	-0.8	-0.5	-0.2	0.4	-0.7	-0.8	-0.6	-1.0	-0.4	0.2	-1.0	0.5
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	3.0	1.3	-0.9	-0.8	0.8	0.6	1.7	1.2	1.0	0.8	1.4	0.5	1.3	0.4	0.2	1.5
Noisy workplace	0.3	0.4	1.9	-1.4	-0.5	0.0	-0.4	-0.4	-0.5	-0.2	-0.4	-0.4	-0.5	-0.4	-0.3	-1.1	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.8	-1.4	-0.1	-0.1	-0.6	-1.0	-0.8	-0.4	-0.5	-0.5	-0.5	-0.5	-0.7	-0.3	-0.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.9	0.8	0.5	0.3	0.7	0.2	0.9	0.4	0.7	0.6	0.7	0.6	0.6	-0.2	0.6	0.2
Age at first live birth	0.3	0.5	3.3	1.8	0.2	-1.2	0.3	0.2	0.3	-0.8	0.4	0.4	0.4	0.4	-0.0	-0.7	0.4	-0.8
Medication: Blood pressure	0.3	0.6	1.0	-0.9	-0.6	-0.3	-0.9	-1.0	-1.0	-0.3	-0.8	-0.9	-0.7	-1.0	-0.6	-0.6	-1.0	-0.1
Overall health rating	0.3	0.6	4.1	-2.0	-0.6	0.7	-0.8	-0.9	-0.7	0.3	-0.7	-0.7	-0.6	-0.8	-0.2	-0.2	-0.8	0.3
Leg pain on walking	0.3	0.4	1.3	-0.8	-0.2	0.6	0.5	0.1	0.8	1.2	0.7	0.5	0.8	0.3	0.8	0.4	0.2	1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.6	0.1	0.5	0.6	0.6	0.7	0.6	0.6	0.5	0.7	0.4	0.7	0.5	0.7	0.7	0.6
Illnesses of father: Heart disease	0.3	0.5	0.9	0.2	0.4	0.6	0.9	0.5	0.5	0.5	0.9	0.8	0.9	0.9	0.7	0.5	0.9	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.5	0.3	-0.7	-0.5	0.5	0.2	1.2	1.2	0.6	0.5	0.9	0.2	1.0	0.3	0.0	1.2
Medication: Gliclazide	0.3	0.3	0.8	-0.6	-0.7	-0.6	-0.5	-0.9	-0.3	-0.3	-0.4	-0.6	-0.3	-0.6	-0.6	-0.2	-0.7	-0.1
Ever taken oral contraceptive pill	0.3	0.3	1.3	-1.2	-0.3	-0.2	-0.3	-0.4	-0.9	-0.7	-0.3	-0.3	-0.4	-0.1	-0.7	-0.8	0.1	-0.9
Commuting to job workplace: Public transport	0.3	0.4	1.0	0.6	0.7	0.1	0.6	0.7	-0.2	-0.4	0.6	0.8	0.4	0.9	0.5	0.1	1.0	-0.4
Number of operations (self-reported)	0.3	0.4	1.1	-0.8	-0.0	0.5	-0.5	-0.3	-1.0	-0.7	-0.6	-0.4	-0.7	-0.3	-0.6	-0.8	-0.1	-0.8
Risk taking	0.3	0.4	1.5	-1.0	-1.2	-0.3	-0.3	-0.6	0.3	0.5	-0.2	-0.3	-0.0	-0.6	-0.0	0.7	-0.7	0.8
Age started oral contraceptive pill	0.3	0.4	1.5	1.2	0.7	-0.8	0.5	0.6	0.3	-0.2	0.6	0.5	0.6	0.6	0.1	0.6	0.6	-0.0
Diastolic blood pressure, automated reading	0.3	1.0	3.9	-2.0	-0.8	-0.2	-1.1	-0.8	-1.8	-0.5	-0.8	-0.9	-0.7	-0.9	-0.9	-0.4	-0.8	-0.4
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.1	0.8	0.5	-0.3	0.8	1.0	1.8	1.1	0.8	0.8	0.9	0.6	1.0	1.2	0.4	1.1
Pain experienced in last month	0.3	0.5	1.9	0.7	-0.4	-1.2	-0.3	-0.3	-0.5	-1.4	-0.5	-0.4	-0.6	-0.3	-0.7	-0.8	-0.2	-1.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	-0.6	-0.2	0.6	-0.7	-0.5	-1.0	-0.4	-0.7	-0.7	-0.8	-0.6	-0.6	-0.5	-0.5	-0.2
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	1.0	1.1	0.9	0.2	0.4	-0.7	-0.8	0.1	0.2	-0.3	0.5	-0.3	0.2	0.7	-0.8
Medication: Co-codamol	0.2	0.2	1.1	-1.1	0.1	0.3	-0.4	-0.5	-0.5	0.1	-0.4	-0.4	-0.4	-0.4	-0.4	0.1	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	-0.7	-0.4	0.2	-0.6	-0.6	-0.4	-0.0	-0.6	-0.6	-0.5	-0.6	-0.4	-0.1	-0.7	0.1
Relative age voice broke	0.2	0.4	1.0	-0.8	-0.4	-0.3	-0.4	-0.7	-0.8	-0.7	-0.6	-0.4	-0.8	-0.3	-1.0	-0.2	-0.2	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.3	1.8	-0.3	0.3	0.2	0.4	-0.1	-0.2	-1.2	0.0	0.3	-0.3	0.5	-0.4	-0.7	0.7	-1.3
Stomach or abdominal pain in last month	0.2	0.2	0.9	-0.0	0.9	0.9	0.3	0.6	-0.1	0.0	0.2	0.3	0.1	0.4	0.1	0.7	0.5	0.1
Supplements: Glucosamine	0.2	0.2	0.7	-0.8	-0.5	-0.8	-0.5	-0.4	-0.3	-0.0	-0.4	-0.5	-0.3	-0.6	-0.5	0.1	-0.6	0.1
Alcohol usually taken with meals	0.2	0.4	1.2	1.1	0.7	0.2	0.4	0.7	0.6	0.7	0.5	0.5	0.6	0.4	0.5	0.5	0.3	0.7
Had menopause	0.2	0.2	0.7	0.7	0.2	-0.2	0.4	0.4	0.6	0.4	0.4	0.3	0.5	0.3	0.2	0.8	0.2	0.5
Mouth/teeth dental problems	0.2	0.3	1.2	1.1	1.1	0.3	0.3	0.7	-0.4	-0.6	0.1	0.2	-0.2	0.5	-0.2	0.2	0.6	-0.6
Impedance of arm (right)	0.2	0.8	4.4	1.0	-0.4	-2.1	0.8	0.4	1.5	0.3	0.8	0.8	1.0	0.5	0.7	0.4	0.4	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	-0.0	0.3	0.1	0.3	0.1	-0.3	-0.6	0.3	0.4	0.2	0.5	-0.2	-0.2	0.7	-0.9
Mouth/teeth dental problems: Dentures	0.2	0.3	2.3	-1.5	-0.6	0.7	-0.3	-0.4	-0.2	0.5	-0.2	-0.3	-0.0	-0.4	0.1	0.5	-0.4	0.7
Prospective memory result	0.2	0.2	1.6	-1.2	-0.4	0.6	0.3	0.1	0.4	0.6	0.0	0.3	-0.1	0.2	0.4	0.5	0.2	0.7
Illnesses of mother	0.2	0.3	0.9	1.0	0.9	0.1	-0.1	0.6	-0.3	-0.8	-0.3	-0.1	-0.6	0.1	-0.2	-0.6	0.2	-0.9
Impedance of arm (left)	0.2	0.9	5.1	0.9	-0.7	-2.2	0.9	0.4	1.6	0.3	0.9	0.8	1.0	0.6	0.8	0.5	0.4	0.5
Medication: Paracetamol	0.2	0.4	2.5	-0.0	1.6	1.3	0.1	0.5	-0.5	-0.4	0.0	0.1	-0.2	0.4	-0.3	-0.1	0.5	-0.8
Gout (self-reported)	0.2	0.3	0.7	-0.7	-0.6	0.6	0.4	0.2	0.3	0.7	0.3	0.4	0.3	0.3	0.6	0.7	0.3	0.8
Medication: Amlodipine	0.2	0.2	0.9	-0.9	-0.9	-0.3	0.1	-0.3	0.3	0.7	0.2	0.1	0.4	-0.1	0.4	0.4	-0.2	0.8
Exposure to tobacco smoke outside home	0.2	0.3	1.4	0.6	1.2	0.9	0.4	0.7	0.2	0.6	0.3	0.4	0.2	0.4	0.3	0.3	0.4	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.2	-0.6	-0.1	-0.1	-0.2	-0.7	-0.6	-1.0	-0.3	-0.2	-0.5	-0.1	-0.7	-0.5	0.0	-1.1
Medication: Seretide 50 evohaler	0.2	0.2	1.2	-1.1	-0.6	0.4	-0.5	-0.4	-0.6	-0.4	-0.5	-0.5	-0.5	-0.4	-0.2	-0.0	-0.3	-0.3
Heart disease (mother)	0.2	0.3	0.7	-0.0	0.3	0.4	0.4	0.2	0.5	0.8	0.5	0.4	0.7	0.3	0.4	0.8	0.2	0.8
Suffer from ‘nerves’	0.2	0.3	1.5	0.0	0.6	0.3	0.5	0.5	0.1	0.4	0.5	0.5	0.5	0.6	0.2	1.2	0.6	0.5
Chest pain or discomfort	0.2	0.3	0.5	-0.6	0.1	0.1	-0.7	-0.6	-0.7	-0.3	-0.7	-0.7	-0.7	-0.7	-0.7	-0.3	-0.6	-0.3
Medication: Aspirin	0.2	0.2	0.9	-0.6	-0.7	0.5	0.1	-0.4	0.1	0.7	0.3	0.1	0.5	-0.1	0.3	0.8	-0.2	0.9
Supplements: Vitamin C	0.2	0.3	1.6	-0.8	-0.6	-0.6	0.3	-0.2	0.6	0.4	0.2	0.3	0.2	0.2	0.4	1.3	0.1	0.7
Average weekly red wine intake	0.2	0.2	0.8	-0.6	-0.9	-0.6	-0.4	-0.5	-0.2	-0.5	-0.4	-0.4	-0.4	-0.4	-0.4	-0.5	-0.4	-0.5
Asthma (self-reported)	0.2	0.3	0.9	0.3	0.2	0.4	0.8	0.3	1.0	0.0	0.5	0.7	0.4	0.7	0.7	0.1	0.8	0.1
Osteoarthritis (self-reported)	0.2	0.2	1.0	-0.5	0.1	0.4	-0.3	-0.3	0.1	0.8	-0.1	-0.2	0.1	-0.4	0.2	1.0	-0.5	1.0
Medication: Aspirin	0.2	0.3	0.8	-0.3	-0.4	0.6	0.4	-0.1	0.3	0.7	0.5	0.3	0.6	0.3	0.5	0.8	0.2	0.9
Average weekly champagne plus white wine intake	0.2	0.3	0.6	0.3	0.2	-0.2	-0.6	-0.1	-0.7	-0.7	-0.6	-0.5	-0.7	-0.4	-0.7	-0.3	-0.3	-0.8
Illnesses of father: High blood pressure	0.2	0.3	1.4	-0.0	-1.1	0.0	0.3	-0.3	0.4	0.2	0.5	0.4	0.7	0.2	0.6	-1.2	0.1	-0.0
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.9	0.5	-0.2	-0.5	0.2	0.1	0.9	0.9	0.3	0.2	0.5	-0.1	0.4	0.5	-0.2	0.9
Commuting to job workplace: Cycle	0.2	0.3	1.3	0.3	0.1	-0.5	0.2	0.2	-0.4	-1.0	0.0	0.3	-0.2	0.4	-0.2	-0.6	0.6	-1.1
Basal cell carcinoma (self-reported)	0.2	0.3	0.8	0.3	0.2	0.6	0.7	0.6	0.2	-0.3	0.6	0.6	0.4	0.8	0.2	-0.1	0.9	-0.4
Impedance of whole body	0.2	0.9	6.0	0.7	-0.8	-2.4	0.6	0.1	1.5	0.6	0.7	0.6	1.1	0.3	0.7	0.3	0.0	0.8
Schizophrenia (2018)	0.1	0.2	1.2	0.2	0.4	0.0	-0.4	-0.2	-1.1	-0.8	-0.4	-0.3	-0.6	-0.1	-0.6	-0.1	-0.0	-0.7
Schizophrenia (2014)	0.1	0.3	1.1	0.4	0.6	0.0	-0.5	-0.1	-1.1	-0.8	-0.5	-0.4	-0.7	-0.3	-0.7	0.1	-0.1	-0.7
Blood Platelet Count	0.1	1.5	5.1	0.1	-1.1	-0.1	0.6	-0.3	2.0	2.2	0.9	0.5	1.4	0.0	1.4	1.1	-0.3	2.2
Systolic Blood Pressure	0.1	0.6	2.2	-1.4	-0.8	-0.4	-0.8	-0.9	-1.5	-0.0	-0.7	-0.7	-0.6	-0.8	-0.6	-0.3	-0.8	0.1
Allergy or Eczema	0.1	0.3	1.0	0.3	0.6	0.4	0.8	0.2	0.5	-0.5	0.5	0.7	0.3	0.9	0.1	-0.2	1.0	-0.7
Respiratory disease	0.1	0.3	0.9	-0.7	-0.9	-0.5	-0.4	-0.9	0.1	-0.4	-0.5	-0.5	-0.5	-0.5	-0.2	-0.5	-0.6	-0.2
Hair Pigment	0.1	1.7	2.5	1.1	1.1	1.3	1.5	1.4	1.6	1.0	1.2	1.5	1.0	1.4	1.6	1.2	1.4	1.0
Tanning	0.1	0.8	1.6	0.4	0.6	1.3	0.8	0.9	0.9	1.1	0.9	0.8	1.0	0.7	1.1	0.8	0.7	1.1
Sensitivity / hurt feelings	0.1	0.2	1.3	-0.6	-1.2	-0.6	-0.2	-0.4	0.1	0.4	0.1	-0.2	0.4	-0.3	0.3	0.2	-0.4	0.5
Relative age of first facial hair	0.1	0.2	0.8	-0.9	-0.4	0.2	0.4	-0.2	0.1	0.3	0.4	0.4	0.3	0.5	-0.0	0.4	0.5	0.2
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	-0.3	-0.4	-0.4	0.1	-0.4	0.4	0.5	0.3	0.1	0.4	-0.0	0.2	0.6	-0.1	0.7
Ever had hysterectomy (womb removed)	0.1	0.1	0.5	0.5	0.7	0.2	0.3	0.6	0.0	0.1	0.3	0.4	0.3	0.5	0.3	-0.0	0.5	0.0
Systolic blood pressure, automated reading	0.1	0.4	2.1	-1.1	-0.2	0.6	-0.6	-0.5	-1.4	-0.2	-0.4	-0.5	-0.4	-0.4	-0.6	-0.2	-0.4	-0.2
Impedance of leg (right)	0.1	0.6	3.3	0.6	-0.1	-1.8	0.6	0.1	1.2	0.8	0.7	0.5	1.0	0.3	0.6	0.3	0.1	0.9
Townsend deprivation index at recruitment	0.1	0.2	1.1	-1.0	0.2	0.8	-0.2	0.0	-0.6	-0.1	-0.3	-0.2	-0.4	-0.0	-0.1	-0.3	0.0	-0.2
High blood pressure	0.1	0.3	1.5	-0.5	-0.4	0.2	-0.4	-0.7	-1.2	-0.7	-0.3	-0.3	-0.4	-0.3	-0.6	-0.9	-0.2	-0.7
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	-0.7	-0.0	-0.1	-0.2	-0.2	-0.2	0.2	-0.1	-0.2	-0.0	-0.2	-0.2	0.6	-0.2	0.2
Impedance of leg (left)	0.1	0.6	4.4	0.4	-0.6	-2.1	0.2	-0.3	1.1	0.7	0.4	0.1	0.8	-0.2	0.4	-0.1	-0.4	0.8
Nervous feelings	0.1	0.1	0.4	-0.5	-0.6	-0.5	-0.1	-0.3	-0.2	0.0	-0.0	-0.0	-0.0	-0.1	0.1	0.5	-0.1	0.3
Forced vital capacity (FVC)	0.1	0.3	2.3	0.3	-1.4	-1.5	-0.0	-0.2	0.5	-0.0	0.1	-0.1	0.4	-0.2	0.2	-0.4	-0.4	0.2
Allergy	0.1	0.3	0.7	-0.3	-0.3	-0.4	-0.7	-0.1	-0.6	0.6	-0.4	-0.6	-0.2	-0.8	-0.3	0.6	-0.9	0.8
Medication: Ramipril	0.1	0.2	0.4	-0.6	-0.2	0.5	-0.4	-0.5	-0.4	0.2	-0.5	-0.3	-0.5	-0.4	-0.3	0.2	-0.4	0.3
Medication: Simvastatin	0.1	0.2	0.4	0.4	-0.1	0.5	0.5	0.2	0.6	0.6	0.5	0.4	0.6	0.3	0.6	0.1	0.2	0.7
Asthma	0.1	0.3	0.8	0.3	0.2	0.5	0.8	0.3	0.9	-0.0	0.5	0.6	0.4	0.7	0.7	0.0	0.7	-0.0
Length of working week for main job	0.1	0.1	0.4	-0.6	-0.2	0.4	-0.2	0.1	-0.0	0.3	-0.2	-0.2	-0.2	-0.2	0.2	0.1	-0.2	0.4
Hair/balding pattern: Pattern 4	0.1	0.1	1.1	-1.0	0.2	0.1	-0.3	-0.1	-0.5	0.0	-0.2	-0.3	-0.2	-0.2	-0.3	0.1	-0.2	-0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.3	-0.4	-0.2	0.2	0.4	0.1	0.3	0.3	0.4	0.4	0.4	0.4	0.5	0.5	0.4	0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.3	0.7	-0.9	-1.1	0.7	0.3	1.1	0.4	0.8	0.6	1.0	0.4	0.8	0.1	0.3	0.5
Number of children fathered	0.1	0.1	0.7	-0.3	0.4	0.8	-0.3	-0.1	-0.2	0.3	-0.4	-0.3	-0.4	-0.3	-0.0	0.0	-0.3	0.3
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.3	-0.1	-0.0	0.2	0.1	0.5	0.5	0.2	0.2	0.3	0.1	0.4	0.6	0.1	0.6
Medication for pain relief, constipation, heartburn	0.1	0.2	1.2	0.6	-0.3	-1.1	0.3	0.1	0.5	0.1	0.1	0.4	0.1	0.2	0.2	0.0	0.2	0.2
Medication: Allopurinol	0.1	0.1	0.5	-0.7	-0.7	0.1	0.0	-0.2	0.0	0.7	0.1	0.1	0.2	-0.1	0.4	0.2	-0.2	0.7
Long-standing illness, disability or infirmity	0.1	0.2	0.9	-0.1	-0.7	-0.4	-0.4	-0.8	0.0	0.3	-0.1	-0.4	0.1	-0.6	0.0	-0.9	-0.7	0.1
Eye problems/disorders: Cataract	0.1	0.2	0.6	0.7	0.3	0.4	0.2	0.7	-0.0	0.3	0.3	0.4	0.2	0.3	0.6	0.1	0.4	0.3
Medication for cholesterol	0.1	0.1	0.4	0.7	0.5	-0.1	-0.2	0.3	-0.2	-0.5	-0.2	-0.2	-0.3	-0.1	-0.3	-0.3	-0.0	-0.6
Mineral and other dietary supplements	0.1	0.2	0.7	-0.1	-0.1	-0.0	-0.3	-0.3	-0.6	-0.7	-0.3	-0.2	-0.3	-0.2	-0.2	-0.8	-0.1	-0.8
Breast cancer (self-reported)	0.1	0.1	0.3	-0.2	-0.4	-0.4	-0.4	-0.2	0.1	0.3	-0.2	-0.3	-0.0	-0.5	0.2	-0.1	-0.6	0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	0.2	-0.4	-0.3	0.2	0.0	-0.3	-0.4	-0.3	-0.4	-0.3	-0.2	-0.0	-0.3	-0.2
Hearing aid user	0.1	0.1	0.5	0.0	-0.7	-0.2	-0.3	-0.6	0.2	0.0	-0.2	-0.3	-0.0	-0.5	-0.0	-0.5	-0.5	0.0
Medication: Blood pressure	0.1	0.1	0.3	-0.5	-0.5	0.2	0.2	-0.4	-0.0	0.6	0.2	0.2	0.3	0.1	0.3	0.1	-0.0	0.5
High cholesterol (Self-reported)	0.1	0.2	0.6	0.0	-0.7	0.4	0.2	-0.3	0.6	0.8	0.3	0.2	0.5	-0.0	0.6	-0.2	-0.1	0.7
Fractured/broken bones in last 5 years	0.1	0.2	0.4	0.7	0.6	0.6	0.3	0.5	-0.2	-0.4	0.2	0.3	-0.0	0.5	0.2	-0.4	0.5	-0.5
Cholesterol lowering medication	0.1	0.1	0.3	-0.3	-0.5	-0.1	0.3	-0.2	0.3	0.3	0.4	0.2	0.5	0.2	0.3	0.0	0.1	0.4
Heart disease (siblings)	0.1	0.2	0.6	-0.3	0.5	0.6	-0.4	-0.3	-0.8	-0.1	-0.4	-0.4	-0.5	-0.3	-0.6	-0.2	-0.2	-0.2
Medication for hormone replacement therapy	0.0	0.0	0.1	-0.3	0.0	0.0	-0.1	-0.0	-0.3	-0.3	-0.2	-0.0	-0.3	0.0	-0.1	0.3	0.1	-0.2
Had other major operations	0.0	0.0	0.1	-0.4	0.1	0.2	0.0	-0.0	-0.1	0.1	0.0	0.0	0.0	0.0	-0.1	-0.2	0.0	-0.1
Pulse wave reflection index	0.0	0.1	0.5	-0.2	0.7	0.1	-0.1	-0.4	-0.1	0.2	0.0	-0.1	0.1	-0.1	-0.2	0.2	-0.1	0.0
Hypertension (Self-reported)	0.0	0.1	0.8	-0.2	-0.2	0.5	-0.1	-0.4	-0.9	-0.2	-0.1	-0.1	-0.1	-0.0	-0.3	-0.5	0.0	-0.3
Medication: Atorvastatin	0.0	0.0	0.1	-0.2	-0.4	-0.2	-0.2	-0.3	-0.2	0.1	-0.1	-0.2	-0.1	-0.2	-0.0	-0.2	-0.3	0.2

Hub : Genes

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Models

Trait associations