TWAS hub - AVL9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0610	0.0230	1.2e-03	0.001	0.009	-0.002	0.008	-0.001	2.0e-01	2.6e-02	6.3e-01	2.8e-02	4.0e-01
2	GTEx	Brain Nucleus accumbens basal ganglia	0.3180	0.0950	1.6e-03	0.027	NA	0.074	NA	0.148	6.5e-02	NA	4.9e-03	NA	9.0e-05
3	GTEx	Esophagus Mucosa	0.1280	0.0380	1.8e-05	0.054	NA	0.074	NA	0.072	1.6e-04	NA	1.1e-05	NA	1.6e-05
4	GTEx	Nerve Tibial	0.1099	0.0365	2.1e-04	0.088	NA	0.101	NA	0.113	9.0e-07	NA	1.3e-07	NA	2.2e-08
5	NTR	Blood	0.0241	0.0084	5.3e-05	0.015	0.011	0.007	0.011	0.008	7.6e-06	1.2e-04	2.3e-03	1.5e-04	8.6e-04
6	YFS	Blood	0.1835	0.0263	0.0e+00	0.176	0.186	0.208	0.211	0.207	2.3e-55	1.3e-58	4.0e-66	4.6e-67	8.8e-66
7	TCGA	Cervical Squamous Cell Carcinoma	0.1700	0.0730	4.9e-04	0.085	0.070	0.060	NA	0.042	5.5e-05	2.4e-04	6.6e-04	NA	3.8e-03
8	TCGA	Colon Adenocarcinoma	0.0650	0.0350	4.6e-03	0.077	0.026	0.028	NA	0.050	3.3e-05	1.2e-02	8.9e-03	NA	7.3e-04
9	TCGA	Lung Adenocarcinoma	0.0591	0.0303	3.7e-03	0.014	0.025	0.025	NA	0.018	7.2e-03	5.9e-04	5.3e-04	NA	3.0e-03
10	TCGA	Thyroid Carcinoma	0.0790	0.0390	1.1e-04	0.012	0.041	0.031	NA	0.019	2.3e-02	6.4e-05	5.1e-04	NA	5.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Ever depressed for a whole week	5.5	6.8	18.0	-3.1	-3.4	2.6	2.2	4.2	1.4	0.5	2.3	1.9	2.4
Neuroticism	4.9	11.9	19.4	-3.5	-3.1	4.4	4.3	3.7	3.1	1.2	4.2	2.4	3.4
Depression (self-reported)	4.7	5.6	9.0	-3.0	-2.7	2.6	2.4	2.9	1.7	1.1	2.6	1.3	2.5
Age at First Birth	4.5	6.5	11.4	2.2	2.1	-2.4	-2.7	-0.8	-2.7	-2.5	-3.4	-3.0	-2.8
Heel bone mineral density (BMD) T-score, automated (right)	4.5	10.4	23.3	0.6	0.5	2.4	3.4	-0.5	4.1	4.8	4.1	4.0	3.6
Tense / ‘highly strung’	4.2	7.0	16.1	-1.1	-0.2	3.7	4.0	1.7	3.0	2.3	3.8	1.6	2.4
Lung cancer (father)	4.0	4.6	8.4	-0.3	-2.6	2.9	2.9	2.9	1.4	1.4	2.3	1.3	1.8
Frequency of tiredness / lethargy in last 2 weeks	3.8	6.1	10.3	-1.1	-2.0	2.6	2.9	2.1	2.6	1.9	2.9	3.2	2.5
Tinnitus: Yes, now most or all of the time	3.6	4.2	7.7	-0.6	0.7	-2.5	-2.8	-0.6	-2.3	-2.2	-2.7	-2.1	-2.2
Neuroticism score	3.5	7.2	11.1	-2.7	-2.4	3.3	3.3	2.9	2.4	1.0	3.2	2.0	2.7
Loneliness, isolation	3.3	4.5	14.0	-0.5	-0.6	2.8	2.7	3.7	1.6	1.0	2.4	1.3	2.1
Neuroticism (Nagel 2018)	3.1	7.3	12.8	-2.2	-2.2	3.5	3.3	3.6	2.2	0.9	3.2	2.1	2.6
Primary Biliary Cirrhosis	3.0	4.2	6.9	-1.2	-1.4	2.4	2.5	0.7	2.4	2.5	2.6	2.0	1.8
Medication: Paracetamol	2.9	4.7	8.8	-1.5	-2.1	2.8	3.0	2.1	1.9	1.1	2.9	1.1	2.4
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	7.0	1.1	0.6	-1.7	-2.1	0.3	-2.6	-2.3	-2.6	-2.0	-2.3
Illnesses of siblings: Diabetes	2.7	3.3	7.5	-1.8	-2.7	0.7	1.2	0.6	2.1	1.6	2.0	1.4	2.7
Qualifications: A levels/AS levels or equivalent	2.6	5.7	10.8	2.2	3.1	-1.7	-2.3	0.0	-2.8	-2.6	-2.8	-0.9	-3.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	10.0	-2.1	-2.4	2.4	2.0	3.2	0.8	-0.0	1.8	1.4	2.0
Commuting to job workplace: Public transport	2.6	3.1	6.1	0.0	1.5	-2.2	-2.5	-0.6	-1.8	-2.2	-2.3	-1.6	-1.4
Depression (Nagel 2018)	2.5	3.7	7.5	-0.2	-0.3	2.6	2.7	1.9	1.6	1.9	2.4	2.2	1.6
Qualifications: CSEs or equivalent	2.5	3.3	8.2	0.5	-0.2	2.1	2.9	1.7	2.3	1.5	2.6	1.6	0.6
Body mass index (BMI)	2.5	10.8	28.8	-3.3	-5.4	2.6	3.0	4.3	2.7	1.0	3.5	1.9	3.1
Qualifications: College or University degree	2.5	7.8	16.6	0.5	2.3	-3.4	-4.1	-0.9	-3.4	-3.4	-3.9	-1.1	-2.1
Medication: Paracetamol	2.5	3.9	8.0	-1.3	-1.3	2.7	2.8	1.4	1.7	1.5	2.7	0.7	2.2
Pack years adult smoking proportion	2.4	3.7	18.1	-0.1	-3.6	1.6	1.2	4.3	-0.1	-0.9	0.7	-0.7	0.2
Pain all over the body in last month	2.3	2.5	4.0	0.9	0.4	-1.8	-2.0	-1.1	-1.9	-1.4	-2.0	-1.6	-1.8
Worry too long after embarrassment	2.3	3.8	11.5	-3.4	-2.7	0.8	1.0	0.5	1.9	1.4	1.7	0.7	2.9
Medication for pain relief, constipation, heartburn	2.3	3.9	7.2	2.7	2.7	-1.8	-2.0	-2.3	-1.7	-0.5	-2.2	-0.5	-2.1
Worry (Nagel 2018)	2.2	4.6	12.2	-0.4	-0.1	3.5	3.0	2.7	1.7	0.7	2.7	1.8	1.7
Leg fat percentage (left)	2.2	8.1	18.7	-2.2	-4.3	2.6	2.8	4.3	2.2	1.0	3.1	1.4	2.6
Pack years of smoking	2.2	3.2	15.2	0.1	-3.4	1.3	0.8	3.9	-0.5	-1.2	0.3	-0.9	-0.1
Depressed Affect (Nagel 2018)	2.1	4.4	9.9	-1.6	-2.7	2.3	2.3	3.1	1.4	0.8	2.2	1.6	1.9
Frequency of depressed mood in last 2 weeks	2.1	3.0	6.0	0.3	-0.6	2.5	2.5	2.4	1.1	1.7	2.0	1.6	0.9
Hearing difficulty/problems with background noise	2.1	3.4	6.8	-1.2	-0.9	2.6	2.4	1.2	1.7	1.9	2.4	1.8	1.6
Fluid intelligence score	2.1	4.4	14.9	-0.1	1.3	-3.9	-3.4	-2.8	-0.8	-0.2	-2.2	1.2	0.0
Age at first live birth	2.1	3.7	9.4	2.7	2.2	-0.5	-1.1	0.0	-2.3	-1.6	-1.9	-1.4	-3.1
Wears glasses or contact lenses	2.1	2.4	5.2	-0.6	-0.5	-2.0	-2.3	-2.2	-1.7	-1.1	-2.0	-0.2	-1.0
Leg fat mass (left)	2.1	8.2	24.2	-2.5	-4.9	2.1	2.6	3.7	2.3	1.1	3.0	1.8	2.8
Neuroticism (2016)	2.0	2.9	6.2	-1.1	-0.6	2.3	2.4	2.5	1.4	0.5	2.2	1.1	1.3
BMI	2.0	11.8	40.1	-3.3	-6.3	2.4	3.1	4.5	2.8	0.7	3.4	1.6	3.1
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.5	8.4	1.0	0.5	2.1	2.5	0.1	2.4	2.9	2.6	2.8	2.1
Ever unenthusiastic/disinterested for a whole week	2.0	2.5	8.5	-1.0	-1.5	2.0	1.8	2.9	0.4	-0.2	1.3	1.9	0.4
Impedance of arm (left)	2.0	9.2	19.1	2.3	4.4	-2.6	-3.4	-1.8	-3.4	-2.3	-3.6	-3.3	-2.3
Headache pain in last month	2.0	3.5	6.1	-0.8	-1.6	2.2	2.4	1.2	2.1	1.9	2.5	1.4	2.0
Illnesses of father: High blood pressure	2.0	2.5	5.0	-0.1	0.0	-1.5	-1.8	-0.2	-2.2	-2.0	-2.0	-2.2	-1.4
Medication for hormone replacement therapy	1.9	2.2	7.4	-1.6	-1.0	0.2	1.0	-1.4	1.9	0.8	1.4	2.7	1.4
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	10.4	1.6	3.2	-2.2	-2.1	-1.2	-1.0	-0.3	-1.8	-0.7	-1.1
Type 2 Diabetes (T2D) (2012)	1.8	2.1	5.5	-0.1	-0.0	1.6	1.8	0.5	2.0	1.9	2.4	0.3	1.4
Diabetes (mother)	1.8	2.3	6.4	-2.4	-2.3	-0.4	-0.3	-0.3	1.0	1.0	0.6	1.6	2.5
Arm fat percentage (right)	1.8	7.2	20.7	-2.9	-4.5	1.8	2.0	3.8	1.8	0.6	2.6	1.0	3.1
Leg fat percentage (right)	1.8	6.6	22.4	-2.3	-4.7	2.0	2.1	4.0	1.6	0.3	2.4	0.9	2.2
Angina (self-reported)	1.8	2.4	6.1	-0.9	-0.3	2.5	2.1	2.0	1.2	0.8	1.9	-0.1	1.7
Leg fat mass (right)	1.8	6.9	26.7	-2.5	-5.2	1.6	2.0	3.4	1.9	0.6	2.5	1.4	2.4
Pulse rate, automated reading	1.8	5.8	10.2	1.5	1.1	-3.0	-3.0	-2.6	-2.4	-2.2	-3.2	-2.0	-2.2
Diabetes diagnosed by doctor	1.8	3.0	5.0	1.6	-1.4	1.8	1.8	1.6	1.2	1.9	1.9	1.8	2.2
Fractured/broken bones in last 5 years	1.8	2.4	6.5	-1.8	-0.0	1.4	0.2	2.5	-1.4	-2.3	-0.4	-1.8	-1.1
Commuting to job workplace: Cycle	1.8	2.2	9.4	-0.4	0.1	-2.3	-1.9	-3.1	0.2	1.2	-1.0	-0.5	0.9
Bipolar Disorder (2011)	1.7	1.7	7.6	1.4	2.8	0.6	0.7	-1.9	0.6	1.2	0.5	0.1	0.8
Sensitivity / hurt feelings	1.7	2.9	5.9	-1.6	-2.4	1.6	2.0	2.2	1.7	0.3	1.9	1.1	1.2
Average weekly fortified wine intake	1.7	2.0	4.8	0.4	0.7	1.0	1.5	-0.5	1.8	2.2	1.6	2.0	0.9
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	6.0	-0.0	-0.4	2.4	2.5	2.3	1.1	1.0	1.9	1.6	0.8
Hip circumference	1.7	7.2	28.1	-3.0	-5.3	0.9	1.4	3.6	1.6	-0.3	2.1	1.7	2.9
Length of working week for main job	1.7	1.8	6.7	-1.3	-0.5	-2.1	-1.4	-2.6	0.7	1.2	-0.4	-0.3	0.9
Ever highly irritable/argumentative for 2 days	1.7	2.0	10.9	-2.1	-3.3	0.3	0.7	1.5	0.8	-0.4	0.8	0.3	0.5
Gout (self-reported)	1.7	2.4	8.4	-0.5	-0.6	-2.9	-2.7	-1.6	-0.5	-0.4	-1.6	-1.4	0.6
Leg pain on walking	1.7	2.1	5.5	-0.5	-1.2	-1.4	-1.9	0.3	-1.7	-2.4	-1.8	-1.2	-0.7
Knee pain experienced in last month	1.7	2.6	5.8	-1.7	-2.4	1.9	1.8	1.8	1.2	0.4	1.7	-0.2	1.4
Mood swings	1.7	3.1	6.4	-2.4	-2.5	1.8	2.0	2.3	1.3	0.2	1.8	0.4	1.3
Arm fat mass (left)	1.7	7.0	22.6	-2.9	-4.7	1.5	2.0	2.7	2.2	1.0	2.7	1.6	3.0
Medication: Blood pressure	1.7	3.2	7.3	1.3	2.4	-2.7	-2.4	-2.6	-0.8	0.3	-1.7	-0.9	0.1
Supplements: Calcium	1.7	1.9	4.5	-0.3	2.1	-1.4	-1.5	-1.1	-1.4	-1.6	-1.5	-0.6	-1.2
Verbal and Numeric Reasoning (VNR)	1.6	3.8	9.0	0.5	2.5	-3.0	-2.9	-2.7	-1.0	-0.6	-2.0	1.2	-0.4
Chronotype (morning person)	1.6	3.7	14.0	2.2	3.7	-0.3	-0.5	-3.7	-0.4	1.7	-0.4	-0.9	0.2
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	7.1	-1.4	-1.7	1.5	1.2	2.7	0.0	-0.9	0.8	-0.5	0.5
Qualifications: None of the above	1.6	3.3	14.7	-2.1	-3.8	1.7	1.9	-0.1	1.3	1.1	1.7	-0.4	1.2
Diabetes (self-reported)	1.6	2.5	4.5	1.1	-1.5	1.4	1.6	1.4	1.3	1.7	1.7	1.8	2.1
Impedance of arm (right)	1.6	7.5	16.7	2.9	4.1	-2.4	-3.0	-1.3	-3.0	-1.7	-3.1	-3.0	-1.6
Neck or shoulder pain in last month	1.6	2.2	7.3	-2.7	-1.5	-1.8	-0.7	-1.5	1.9	0.3	0.5	0.5	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	7.1	-1.6	-0.9	1.6	1.6	2.7	0.9	0.2	1.4	-0.1	0.8
Arm fat percentage (left)	1.6	6.6	19.4	-3.2	-4.4	1.7	1.8	3.6	1.6	0.3	2.4	0.8	2.8
Irritability	1.6	2.8	8.8	-3.0	-2.6	0.8	1.2	1.1	1.5	-0.7	1.3	1.3	1.6
Ever had prostate specific antigen (PSA) test	1.6	1.8	8.6	1.7	0.6	1.0	0.2	2.9	-1.2	-1.3	-0.4	-1.1	-1.0
Breast Cancer	1.5	3.7	8.7	0.8	0.4	-1.4	-1.9	1.2	-2.3	-2.6	-2.3	-2.9	-1.7
Schizophrenia (2014)	1.5	3.4	6.4	-1.7	-2.3	2.5	2.3	1.2	1.6	1.0	2.3	0.6	1.7
Angina	1.5	1.9	4.4	-1.1	-0.5	2.1	1.8	1.9	1.0	0.5	1.6	-0.4	1.6
Had menopause	1.5	1.8	3.8	-0.1	0.9	0.3	0.5	-1.9	1.4	2.0	1.0	1.9	1.7
Arm fat mass (right)	1.5	6.2	21.7	-2.5	-4.7	1.5	1.9	3.2	1.8	0.5	2.5	1.4	2.5
Medication: Ventolin 100micrograms inhaler	1.5	1.9	3.8	0.2	1.0	-0.7	-1.1	0.3	-1.6	-2.0	-1.5	-1.8	-1.9
Suffer from ‘nerves’	1.5	2.3	9.9	-0.7	0.5	3.1	2.1	2.4	0.0	-0.8	1.2	0.1	0.3
Guilty feelings	1.5	2.3	7.4	-0.1	1.0	2.7	2.1	2.4	0.5	0.6	1.6	0.4	1.1
Medication: Atorvastatin	1.5	1.9	7.1	0.3	-0.8	2.1	1.7	2.7	0.7	1.0	1.4	0.4	0.7
Age started oral contraceptive pill	1.5	1.8	4.0	0.1	0.6	-1.6	-1.8	-0.5	-1.6	-2.0	-1.8	-0.7	-1.3
Impedance of whole body	1.5	7.6	23.9	3.5	4.9	-1.7	-2.4	-2.2	-2.5	-1.0	-2.8	-2.6	-2.0
Other serious medical condition/disability diagnosed by doctor	1.4	1.9	5.4	-2.3	-1.7	-0.9	-0.1	-1.0	1.6	0.7	0.8	1.4	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	4.2	-0.4	-0.4	1.6	1.8	2.1	0.9	0.8	1.5	2.0	0.9
Forced vital capacity (FVC), Best measure	1.4	5.2	17.9	0.5	1.0	-3.5	-3.2	-4.2	-1.4	-0.6	-2.5	0.3	-1.4
Exposure to tobacco smoke outside home	1.4	1.8	4.0	-0.9	-2.0	-1.9	-1.6	-1.4	-0.2	-1.1	-1.2	-1.3	-0.5
Osteoporosis (self-reported)	1.4	1.7	3.8	1.3	0.2	-0.7	-1.3	0.3	-2.0	-1.5	-1.6	-1.4	-1.6
Coronary Artery Disease (CAD)	1.3	1.5	5.3	0.7	-2.3	0.7	1.2	1.8	1.3	0.5	1.0	0.9	0.4
Mean Putamen Volume	1.3	1.5	3.3	0.0	1.1	-1.8	-1.8	-1.5	-1.2	-0.8	-1.5	-0.4	-0.6
Number of treatments/medications taken	1.3	2.4	6.0	-2.5	-1.3	0.9	1.4	1.2	1.9	1.0	1.9	0.6	1.9
Impedance of leg (right)	1.3	6.3	16.0	4.0	4.0	-1.4	-2.0	-2.0	-2.1	-0.6	-2.5	-2.3	-2.1
Fed-up feelings	1.3	2.4	4.5	-0.2	-2.1	1.1	1.7	2.0	1.6	1.1	1.7	1.4	1.5
Age when periods started (menarche)	1.3	3.2	8.4	2.4	-1.4	0.2	-0.1	1.3	-2.0	-2.6	-1.5	-1.0	-2.9
Breastfed as a baby	1.3	1.6	4.5	1.2	1.6	0.3	0.4	-0.8	0.7	2.1	0.9	1.8	1.5
Ever had bowel cancer screening	1.3	1.5	4.1	0.4	1.8	-1.7	-1.6	-2.0	-0.3	-0.2	-1.1	-0.5	-0.8
Eye problems/disorders: Cataract	1.3	1.5	4.6	-1.9	-2.2	0.3	0.6	0.2	1.3	0.6	1.1	0.1	1.8
Osteoarthritis (self-reported)	1.3	1.7	3.1	-0.4	-0.1	-1.4	-1.5	-0.6	-1.1	-1.7	-1.7	-1.5	-1.8
Smoking Status	1.2	2.8	5.8	-1.0	-2.2	-1.4	-1.6	0.6	-1.6	-2.4	-1.9	-2.0	-1.1
Waist circumference	1.2	4.3	19.1	-2.1	-4.4	0.6	1.2	2.2	1.5	0.8	1.9	0.9	2.3
Heart attack	1.2	1.6	3.4	-1.1	-1.5	1.1	1.0	1.2	0.8	1.0	1.3	1.4	1.9
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	4.2	0.8	-2.0	1.4	1.7	1.9	1.6	1.7	1.7	1.3	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.2	-1.3	0.3	2.1	1.1	1.9	-1.2	-1.4	0.2	-1.1	0.2
Whole body fat mass	1.2	5.1	20.0	-2.0	-4.5	1.2	1.7	2.7	1.6	0.6	2.2	1.4	2.3
Back pain experienced in last month	1.2	1.7	3.4	-0.4	-1.0	1.5	1.9	0.4	1.6	1.0	1.8	1.6	1.1
Medication: Gliclazide	1.2	1.4	3.8	-0.4	-0.2	2.0	1.6	1.0	0.7	1.4	1.5	-0.1	1.1
High cholesterol (Self-reported)	1.2	2.1	5.5	-1.9	-2.4	1.1	1.2	0.9	1.2	1.4	1.4	0.3	1.6
Intelligence (Savage-Jansen 2018)	1.1	3.3	14.1	0.8	3.8	-2.4	-2.3	-1.7	-0.6	0.2	-1.4	1.5	-0.0
Schizophrenia vs Biploar Disorder	1.1	1.4	3.1	-1.8	-0.9	0.2	0.2	1.2	1.2	1.0	1.0	1.5	1.7
Alzheimer’s Disease (including proxy)	1.1	1.6	5.0	-1.0	-1.4	1.9	2.2	0.5	1.1	0.6	1.5	0.7	-0.5
Heel T-Score	1.1	9.1	21.4	0.7	1.8	-0.4	1.4	-3.7	4.2	4.6	2.9	2.7	4.0
Cardiovascular Disease	1.1	3.6	11.1	-0.5	-1.0	0.7	1.6	0.4	2.5	2.3	2.3	1.9	3.3
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	6.7	-0.2	-2.6	-0.6	-0.6	-0.9	-0.7	-0.4	-0.7	-1.6	-0.0
Medication: Co-codamol	1.1	1.3	4.2	-0.9	-0.8	2.0	1.6	1.6	0.5	0.3	1.3	-0.0	0.7
Medication: Atenolol	1.1	1.4	3.7	0.1	0.5	0.9	1.2	0.7	1.5	1.9	1.5	0.8	1.4
Impedance of leg (left)	1.1	5.6	22.9	4.1	4.8	-0.6	-1.2	-1.8	-1.5	0.2	-1.7	-1.7	-1.5
Forced vital capacity (FVC)	1.1	4.4	11.7	0.6	1.0	-3.0	-2.9	-3.4	-1.7	-0.7	-2.5	0.7	-1.7
Weight	1.1	5.4	21.3	-2.0	-4.6	1.1	1.8	2.2	1.9	0.9	2.4	2.0	2.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	5.2	1.9	2.3	-1.0	-1.0	-1.3	-0.9	-0.5	-1.2	0.2	-1.6
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.3	0.9	1.1	-0.8	-1.1	0.6	-1.5	-1.0	-1.3	-1.4	-1.4
Body fat percentage	1.1	4.4	15.0	-2.0	-3.9	1.4	1.5	3.1	1.3	0.2	1.9	0.8	2.2
Mean time to correctly identify matches	1.1	2.0	5.5	0.3	-0.3	1.6	1.8	-0.8	1.7	2.3	1.8	0.4	1.5
Overall health rating	1.1	2.3	7.4	-2.3	-1.9	0.6	0.7	-0.2	1.4	1.3	1.3	0.3	2.7
Had major operations	1.1	1.3	4.6	-0.4	-2.1	1.1	0.8	1.9	0.1	-0.3	0.5	1.4	-0.2
Age at last live birth	1.1	1.5	6.4	2.5	1.6	-0.6	-0.5	0.1	-1.0	-1.0	-0.9	-0.3	-1.7
Medication: Aspirin	1.1	1.4	8.2	-2.9	-1.2	0.4	0.3	0.9	0.7	-0.2	0.6	0.5	1.3
Eye problems/disorders: Glaucoma	1.1	1.3	4.5	-2.1	-1.8	0.9	0.9	1.2	0.5	0.4	0.9	-0.3	0.5
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.0	-0.8	-1.3	1.0	1.0	1.5	0.6	0.9	1.2	1.2	1.7
Arm predicted mass (left)	1.1	5.5	15.1	-1.0	-3.9	1.1	2.1	0.3	2.6	2.1	2.7	3.3	2.1
Crohns Disease (2012)	1.0	1.6	6.4	1.7	2.5	-0.5	-0.1	-0.5	1.1	1.7	0.6	1.5	0.3
Hypothyroidism (self reported)	1.0	2.2	3.9	1.0	-0.8	1.5	2.0	1.8	1.7	1.7	1.8	1.4	0.6
Lung FVC	1.0	5.1	11.9	-1.3	0.6	-2.8	-3.5	-2.1	-2.5	-2.0	-3.1	-0.4	-2.1
Diabetes (father)	1.0	1.3	5.9	0.5	-1.6	1.4	0.7	2.4	-0.8	-0.3	0.3	-0.7	0.3
Medication: Levothyroxine sodium	1.0	1.7	5.4	0.0	-2.3	0.9	1.0	2.3	1.1	1.1	1.2	0.4	0.6
Medication: Simvastatin	1.0	1.4	4.6	-2.1	-1.5	0.1	0.2	-0.0	1.0	1.0	0.9	0.5	2.2
Birth weight	1.0	2.2	6.8	0.5	1.8	-2.6	-2.3	-1.8	-0.5	-0.3	-1.6	-0.1	-0.6
Number of full brothers	1.0	1.3	2.8	-1.6	-1.7	-1.3	-0.2	-1.0	1.5	0.5	0.5	0.7	1.2
Supplements: Vitamin C	1.0	1.1	3.0	-1.0	1.2	-0.8	-0.7	-1.0	-0.9	-1.4	-1.0	-0.4	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	4.9	-2.2	-1.5	-1.1	-0.6	0.3	0.5	-0.1	0.1	0.7	1.1
Miserableness	1.0	1.7	3.6	-1.3	-1.9	1.2	1.2	1.0	1.1	0.7	1.4	1.3	1.4
Hearing aid user	1.0	1.1	4.9	-0.2	1.6	-1.3	-1.0	-2.2	0.4	0.3	-0.4	0.5	0.6
Arm fat-free mass (left)	1.0	5.1	15.1	-1.2	-3.9	0.8	1.8	0.1	2.5	2.1	2.5	3.0	2.1
Average weekly beer plus cider intake	1.0	1.4	4.8	0.6	0.9	-0.1	-0.5	1.4	-1.3	-2.2	-1.0	-0.8	-1.5
Alzheimer’s Disease (in father)	0.9	1.0	3.4	0.0	-0.2	0.7	0.8	1.7	-0.5	-1.3	-0.0	0.2	-1.8
Type 2 Diabetes (T2D) (2018)	0.9	1.7	2.8	1.6	-0.5	1.2	1.3	1.3	0.8	1.3	1.4	1.6	1.7
Hearing difficulty/problems: Yes	0.9	1.4	2.9	-1.1	-1.7	1.1	1.1	0.6	1.3	0.9	1.3	1.3	1.1
Systolic blood pressure, automated reading	0.9	2.6	6.5	0.7	1.6	-2.5	-2.4	-2.3	-1.0	-0.5	-1.7	-0.6	-1.0
Medication: Metformin	0.9	1.3	2.1	1.5	-1.1	1.2	1.2	0.9	0.7	1.1	1.2	1.2	1.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.4	0.7	1.2	-0.8	-1.2	-1.5	-0.9	-0.4	-1.1	-1.1	-0.9
Trunk fat mass	0.9	4.0	15.8	-1.7	-4.0	1.1	1.5	2.3	1.4	0.6	1.9	1.2	2.2
Nervous feelings	0.9	1.7	5.2	-1.1	-0.5	2.3	1.5	2.3	0.3	-0.5	1.2	-0.1	0.9
Father’s age at death	0.9	1.2	3.5	0.5	1.1	-0.8	-1.1	-0.5	-1.4	-1.9	-1.3	-0.5	-1.1
Mouth/teeth dental problems: Dentures	0.9	1.5	5.2	-0.3	-1.0	-0.7	-0.3	-2.3	1.1	1.8	0.5	0.2	1.7
Medication: Cholesterol lowering	0.9	1.4	5.6	-2.1	-2.4	0.1	0.1	1.7	0.1	-0.4	0.2	-0.8	0.4
Prospective memory result	0.9	1.2	4.7	-1.3	-0.3	1.3	1.0	2.2	-0.1	-1.0	0.3	-1.0	-0.6
Number of children fathered	0.9	1.0	3.8	1.4	0.4	-0.9	-0.0	-1.9	1.0	1.3	0.3	0.8	-0.0
Shortness of breath walking on level ground	0.9	1.1	4.4	-2.1	-2.1	-0.2	0.1	-0.2	0.8	-0.8	0.3	0.5	0.7
Medication: Blood pressure	0.9	1.6	3.9	-1.0	-0.9	1.4	1.4	1.3	1.3	0.8	1.5	0.4	2.0
Number of full sisters	0.9	1.1	4.5	2.1	2.0	-0.9	-0.8	-0.5	-0.0	0.9	-0.5	0.4	-0.2
Medication: Aspirin	0.9	1.1	7.1	-2.7	-0.9	0.4	0.1	1.3	0.2	-0.5	0.3	0.4	1.0
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.2	2.0	1.7	-0.2	-0.7	1.1	-1.4	-0.3	-1.0	-0.4	-1.6
Myopia	0.9	1.3	4.8	-1.0	-1.0	-0.7	-0.7	1.5	-0.8	-2.2	-0.8	-0.6	-1.0
Cholesterol lowering medication	0.9	1.3	5.8	-0.4	-0.3	0.7	0.7	-0.0	1.2	1.6	1.2	1.0	2.4
Heart disease (siblings)	0.9	1.1	2.8	0.4	-0.6	1.0	1.7	0.7	1.6	0.9	1.5	0.8	-0.2
Bipolar Disorder (2018)	0.8	1.2	2.7	1.4	0.6	1.4	1.6	-0.9	0.7	1.2	1.2	1.0	0.0
Rheumatoid Arthritis	0.8	1.1	3.3	0.4	1.3	-0.5	-0.5	0.4	-0.9	-1.8	-1.0	-1.4	-1.4
Lung FEV1/FVC ratio	0.8	4.3	13.7	-1.3	-3.7	-2.2	-2.2	0.3	-1.8	-1.9	-2.2	-1.9	-1.3
Vitamin and mineral supplements	0.8	1.0	2.4	-0.1	-1.5	0.3	0.4	0.2	1.1	1.1	1.0	1.5	1.5
Leg fat-free mass (left)	0.8	4.1	20.7	-2.3	-4.5	0.4	1.2	1.1	1.5	0.5	1.7	2.1	1.6
Serious illness, injury or assault to yourself	0.8	0.9	4.0	-0.7	-0.3	1.3	1.0	2.0	0.3	0.1	0.8	0.0	1.0
Leg predicted mass (left)	0.8	4.3	21.0	-2.4	-4.6	0.5	1.3	1.1	1.5	0.5	1.8	2.1	1.7
Peak expiratory flow (PEF)	0.8	1.8	7.1	-1.1	-2.7	-0.5	-0.1	2.5	0.1	-1.3	-0.0	0.8	-0.6
Emphysema/chronic bronchitis	0.8	0.9	6.3	-1.5	-2.5	0.1	0.0	0.2	0.3	-0.2	0.1	-0.6	0.2
Medication: Allopurinol	0.8	1.1	4.6	-0.2	-0.3	-2.1	-1.6	-1.4	0.4	0.6	-0.6	-0.9	0.5
Leg fat-free mass (right)	0.8	4.4	16.1	-2.4	-4.0	0.6	1.5	1.0	1.8	0.9	2.1	2.5	1.9
Leg predicted mass (right)	0.8	4.3	16.3	-2.3	-4.0	0.6	1.4	1.0	1.8	0.8	2.0	2.5	1.9
Basal metabolic rate	0.8	4.2	17.1	-1.6	-4.1	0.8	1.6	0.9	1.8	1.1	2.1	2.4	1.9
Irritable Bowel Disease (IBD)	0.7	1.6	6.0	2.1	2.4	-0.9	-0.1	-0.6	1.1	1.2	0.4	1.2	0.1
Fasting Glucose	0.7	0.8	4.0	-0.7	-0.3	-2.0	-1.3	-0.6	-0.2	-0.9	-1.1	-0.0	-0.0
Trunk fat percentage	0.7	3.0	10.9	-1.5	-3.3	1.0	1.2	2.5	0.9	0.1	1.6	0.7	1.9
Maternal smoking around birth	0.7	1.0	4.2	-0.7	-0.8	-2.0	-1.5	-0.7	-0.4	-0.4	-1.1	-0.3	-0.4
Stomach or abdominal pain in last month	0.7	0.9	2.4	0.3	0.7	1.5	1.2	0.3	0.7	1.5	1.1	0.4	0.8
Sitting height	0.7	4.9	19.4	1.2	0.3	-1.7	-0.6	-4.4	1.5	2.3	0.5	3.5	2.2
Number of incorrect matches in round	0.7	1.1	2.1	-1.1	0.8	1.4	1.4	0.5	1.2	0.5	1.4	-0.2	1.2
Alcohol usually taken with meals	0.7	1.1	3.9	-1.2	1.4	0.2	0.2	0.1	0.8	0.8	0.7	2.0	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	4.4	-1.5	-2.1	-0.1	0.1	0.9	0.2	-0.7	0.2	-0.3	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	6.4	0.2	0.0	-2.5	-2.3	-2.5	-1.0	-0.6	-1.8	0.3	-1.0
Arm fat-free mass (right)	0.7	3.8	11.4	-1.3	-3.4	0.9	1.8	0.0	2.1	1.5	2.1	2.8	1.4
Eye problems/disorders: None of the above	0.7	0.8	3.8	1.3	2.0	-0.5	-0.3	-0.5	-0.2	0.1	-0.4	0.6	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.0	0.7	-0.3	0.8	0.9	1.4	0.5	0.3	0.9	1.4	0.8
Family relationship satisfaction	0.7	0.9	1.8	0.6	-0.3	1.3	1.1	1.3	0.6	1.0	0.9	1.1	0.6
Qualifications: nursing, teaching	0.7	1.1	2.8	1.1	0.9	-1.7	-1.5	-0.6	-0.6	-0.6	-1.3	0.5	-0.7
Medication for cholesterol	0.7	1.0	4.3	0.2	-0.3	1.6	1.3	2.1	0.1	-0.2	0.7	0.0	-0.8
Alcohol drinker status: Never	0.7	0.9	2.2	1.5	0.7	1.4	1.2	1.3	0.2	0.4	0.7	0.2	0.0
Pain experienced in last month	0.7	1.2	2.0	1.1	1.4	-1.1	-1.2	-1.1	-1.1	-0.2	-1.2	-0.3	-1.4
Crohns Disease (2017)	0.6	1.4	5.2	1.5	2.3	-1.3	-0.5	-1.4	0.9	1.0	0.1	0.6	0.1
Major Depression (MDD)	0.6	0.7	2.1	-1.4	-1.5	-0.2	0.1	0.8	0.7	0.2	0.4	-0.2	1.2
Reaction Time	0.6	1.1	3.0	0.8	-0.0	1.3	1.4	-0.7	1.0	1.7	1.2	0.0	0.7
Townsend deprivation index at recruitment	0.6	0.8	4.1	-0.9	-2.0	-0.2	-0.1	0.2	0.6	0.4	0.3	1.2	0.9
Hair/balding pattern: Pattern 2	0.6	0.8	2.4	-1.6	-0.1	-1.2	-0.3	-0.6	1.0	0.5	0.3	0.7	1.4
Illnesses of siblings	0.6	0.9	2.3	0.7	1.5	0.4	0.0	-0.8	-1.1	-1.0	-0.9	-0.7	-1.4
Alcohol intake versus 10 years previously	0.6	0.8	2.5	-1.1	-1.6	0.2	0.2	-0.2	1.0	0.8	0.6	0.1	1.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	4.8	0.4	0.0	-2.2	-1.9	-1.8	-1.2	-0.8	-1.7	0.6	-1.6
Happiness	0.6	0.7	3.3	0.7	0.4	0.9	0.7	1.8	0.1	0.0	0.6	1.2	0.4
Birth weight of first child	0.6	1.0	3.6	0.7	1.9	0.1	0.4	-1.2	0.7	1.6	0.5	1.2	0.2
Blood clot in the leg (DVT)	0.6	0.8	2.7	-1.6	-0.7	-1.5	-0.7	-0.9	0.9	0.6	0.1	-0.2	0.5
Glaucoma (self-reported)	0.6	0.7	2.3	-1.5	-1.5	0.5	0.4	1.4	-0.1	0.2	0.4	-0.4	0.2
Medication: Amlodipine	0.6	0.9	1.8	0.8	0.3	-1.3	-1.3	-0.8	-1.1	-0.7	-1.3	-0.1	-0.9
Comparative body size at age 10	0.6	1.6	3.3	-0.9	-1.4	0.0	0.9	1.2	1.8	1.3	1.6	-0.2	1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.2	0.1	0.3	-0.2	0.5	-1.2	1.0	1.5	0.8	0.4	0.9
Arm predicted mass (right)	0.6	3.1	10.9	-1.1	-3.3	0.6	1.4	-0.3	1.8	1.4	1.8	2.6	1.3
Alcohol intake frequency.	0.6	1.4	5.8	-0.4	-2.4	1.2	1.1	1.9	0.7	0.2	0.9	-0.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.3	-0.6	-1.2	-0.2	0.3	-0.9	1.2	1.5	0.8	1.5	1.5
Whole body fat-free mass	0.6	3.6	13.2	-1.3	-3.6	0.7	1.5	0.4	1.8	1.3	2.0	2.5	1.7
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.2	0.8	0.7	-0.1	0.2	-1.5	0.9	1.3	0.6	0.9	0.6
Mineral and other dietary supplements	0.6	0.8	5.0	-0.2	-2.2	0.4	0.1	0.5	0.1	0.4	0.3	0.5	1.2
Whole body water mass	0.6	3.6	13.6	-1.3	-3.7	0.6	1.5	0.3	1.8	1.3	2.0	2.6	1.6
Number of self-reported non-cancer illnesses	0.6	1.0	3.7	-1.7	-1.9	-0.6	-0.5	1.2	0.2	0.2	0.2	-0.4	1.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	3.6	-0.8	-0.7	0.6	0.8	1.9	0.7	-0.5	0.7	-0.1	0.1
Ulcerative Colitis (UC)	0.5	0.9	3.3	1.5	1.8	-0.3	0.3	0.1	0.8	1.0	0.6	1.2	0.1
Body Mass Index (BMI) (2010)	0.5	0.7	2.3	-1.5	-1.0	0.3	0.6	-0.4	1.2	0.5	0.8	-0.2	1.0
Triglycerides	0.5	0.8	1.9	0.7	-0.3	0.5	0.9	0.5	1.2	1.4	1.3	0.7	0.8
Ulcerative Colitis	0.5	0.8	2.0	1.2	0.6	-0.1	0.5	0.1	1.2	1.4	0.9	1.2	0.4
Height	0.5	9.9	46.0	4.1	0.9	-4.3	-2.9	-6.8	-0.7	1.0	-2.2	1.1	-1.1
Waist Hip Ratio (WHR)	0.5	2.2	6.7	2.4	1.9	-0.5	-0.6	-2.6	-0.3	1.8	-0.5	-0.7	-0.9
Systolic Blood Pressure	0.5	2.3	7.8	0.7	2.0	-2.8	-2.2	-2.1	-0.3	-0.0	-1.2	0.2	0.2
Average weekly spirits intake	0.5	0.6	2.0	0.1	-1.4	1.4	1.1	0.5	0.2	-0.5	0.5	0.0	0.1
Current tobacco smoking	0.5	0.8	6.0	-0.5	-2.5	-0.5	-0.2	0.8	0.4	-0.4	-0.2	-0.8	-0.0
Relative age voice broke	0.5	0.7	3.1	-0.4	-0.6	1.2	1.1	1.8	0.1	-0.5	0.5	-0.2	-0.5
Trunk fat-free mass	0.5	2.9	8.5	-0.5	-2.9	0.5	1.4	-0.2	1.8	1.7	1.9	2.5	1.6
Worrier / anxious feelings	0.5	1.0	3.2	-1.5	-1.5	0.7	-0.0	1.8	-0.6	-1.1	-0.0	0.0	0.2
Falls in the last year	0.5	0.7	2.6	0.7	-0.6	-0.2	-0.3	1.6	-0.4	-0.7	-0.5	-1.1	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.6	1.0	1.6	-0.0	-0.2	0.9	-0.5	-0.9	-0.5	0.2	-0.7
Medication: Lansoprazole	0.5	0.6	2.2	-1.5	0.4	0.4	0.2	0.8	-0.4	-0.8	0.0	-1.3	0.1
Trunk predicted mass	0.5	3.1	8.2	-0.5	-2.9	0.5	1.4	-0.3	1.9	1.8	1.9	2.6	1.7
Standing height	0.5	5.0	19.5	2.8	1.4	-2.9	-2.3	-4.4	-1.2	0.3	-1.9	0.6	-1.1
Hair/balding pattern: Pattern 4	0.5	1.2	2.8	-1.7	-1.6	0.6	0.8	0.1	1.4	1.1	1.2	0.4	1.1
Loud music exposure frequency	0.5	0.6	2.1	-0.6	-0.3	-0.9	-0.8	-0.2	-0.7	-1.5	-0.8	-0.5	-0.6
Health satisfaction	0.5	0.6	1.7	-0.1	-0.7	0.7	0.8	0.9	0.7	0.3	0.9	0.5	1.3
Medication: Ibuprofen	0.5	0.6	2.1	-1.4	-1.4	0.3	0.2	0.9	0.0	-0.3	0.3	-0.5	0.6
Medication: Omeprazole	0.5	0.6	1.6	-0.9	-1.3	0.0	0.6	1.0	1.2	-0.1	0.8	0.1	0.7
Heart disease (mother)	0.5	0.5	1.4	0.4	1.0	-0.7	-1.1	-0.1	-1.2	-0.4	-0.9	0.4	-0.2
Average weekly red wine intake	0.5	0.8	2.9	0.2	1.7	-1.0	-0.8	0.1	-0.6	-0.9	-0.9	-0.6	-1.0
Commuting to job workplace: Walk	0.5	0.5	2.3	-0.9	-0.7	-0.2	-0.4	-1.5	-0.1	0.9	-0.1	0.3	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.4	-0.9	-1.0	-0.1	-0.3	-1.2	-0.6	-0.6	-0.5	-1.0	-0.0
Smoking status: Current	0.5	0.7	4.4	-0.3	-2.1	-0.7	-0.4	0.6	0.1	-0.6	-0.5	-0.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.1	0.3	0.1	-1.4	-1.4	-1.3	-0.7	-0.8	-1.2	0.4	-1.1
Financial situation satisfaction	0.5	0.6	1.5	-1.1	-1.2	0.6	0.6	0.8	0.6	0.0	0.6	0.9	0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	4.1	-1.1	-2.0	-0.4	-0.2	-0.2	0.3	-0.6	0.1	-0.5	0.6
Number of operations (self-reported)	0.5	0.8	2.8	-0.6	-1.7	-0.5	-0.6	1.7	-0.7	-0.2	-0.4	0.8	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.0	-1.4	-0.5	-1.2	-0.5	-0.8	0.9	0.6	0.2	-0.2	0.4
Bipolar Disorder or Schizophrenia	0.4	1.0	3.8	0.2	-0.4	2.0	1.7	-0.1	0.6	0.6	1.2	-0.5	0.2
Schizophrenia (2018)	0.4	0.7	2.0	-0.8	-1.1	1.4	0.9	0.6	0.2	-0.2	0.7	-1.4	0.2
HbA1C	0.4	0.4	1.2	0.9	-1.1	-0.5	0.2	-0.4	0.8	0.6	0.4	0.4	0.1
Relative age of first facial hair	0.4	0.9	3.8	-0.0	-1.3	1.1	1.1	1.9	0.5	-0.1	0.7	0.1	0.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.5	0.4	0.1	0.3	0.5	-0.8	0.6	1.0	0.5	1.2	0.8
Supplements: Zinc	0.4	0.5	1.4	-1.2	-0.9	0.7	0.8	0.5	0.6	-0.3	0.6	0.2	0.3
Severe depression (siblings)	0.4	0.5	1.0	0.1	-1.0	-0.7	-0.8	0.8	-0.8	-0.9	-0.6	0.4	0.3
Supplements: Glucosamine	0.4	0.5	1.8	0.2	1.1	-0.0	-0.3	0.9	-0.8	-0.7	-0.6	-0.3	-1.4
Had other major operations	0.4	0.5	2.7	0.3	0.3	0.3	-0.3	1.6	-1.3	-0.6	-0.6	0.2	-0.1
Pulse rate	0.4	0.7	1.6	-0.8	-1.3	-0.9	-0.9	-0.8	-0.4	-1.0	-0.8	-0.7	-0.2
Noisy workplace	0.4	0.5	1.2	-0.2	-0.3	0.9	0.9	-0.5	0.7	0.8	0.9	0.4	1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	3.3	0.9	-1.8	-0.3	0.0	-0.0	0.4	0.7	0.2	0.2	0.1
Hypertension (Self-reported)	0.4	1.1	5.1	-0.3	0.3	-0.3	0.2	-0.6	1.5	1.4	1.0	0.6	2.3
Illnesses of father: Heart disease	0.4	0.6	1.9	0.3	0.8	-1.4	-1.3	-0.1	-0.8	-0.4	-0.9	-0.2	0.0
Long-standing illness, disability or infirmity	0.4	0.6	2.6	-0.2	-1.6	-0.6	-0.1	-0.1	1.0	0.6	0.6	0.3	1.2
Breast cancer (self-reported)	0.4	0.5	1.9	1.4	0.7	0.9	0.6	-0.7	-0.4	0.3	0.1	-0.7	-0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	1.4	-1.0	-0.2	-0.4	0.1	-1.2	1.0	0.7	0.4	0.4	0.8
Mother’s age at death	0.4	0.5	2.6	0.9	1.6	-0.0	-0.2	-0.8	-0.3	0.1	-0.2	0.7	-0.1
Medication: Lisinopril	0.4	0.6	2.1	0.4	0.2	-0.1	0.4	-0.4	1.0	1.4	0.6	0.8	1.0
Risk taking	0.4	0.6	1.8	-0.2	-1.3	0.5	0.3	1.3	-0.5	-1.3	-0.2	-0.3	-0.5
Ovarian Cancer	0.3	0.3	0.9	0.9	-0.3	0.6	0.9	0.6	0.4	-0.5	0.6	0.3	-0.1
Prostate Cancer	0.3	0.5	1.4	0.7	-0.4	1.2	1.1	0.3	0.5	0.2	0.8	0.6	-0.2
LDL Cholesterol	0.3	0.4	1.5	0.4	0.9	-0.9	-0.4	-0.2	0.6	0.2	-0.2	-1.2	-0.0
Blood Eosinophil Count	0.3	2.0	5.8	-1.1	-1.1	-2.3	-2.4	0.6	-0.8	-1.2	-1.8	-0.1	-0.5
Blood Red Count	0.3	2.5	4.6	-2.1	-1.6	1.3	1.4	2.1	1.7	0.4	1.9	1.2	1.5
Respiratory disease	0.3	0.6	3.7	-1.9	-1.0	-0.4	-0.1	0.1	0.8	0.2	0.3	0.2	0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.9	-0.1	-1.4	0.3	-0.1	0.1	-0.7	-0.7	-0.5	0.7	-0.3
Taking other prescription medications	0.3	0.5	3.6	0.1	-0.5	0.6	0.4	1.9	-0.1	-0.5	0.4	-0.5	0.2
High blood pressure	0.3	0.8	4.2	-0.2	0.4	-0.3	0.1	-0.3	1.2	1.2	0.8	0.3	2.0
Multivitamins +/- minerals	0.3	0.4	1.3	0.4	0.6	1.1	1.1	0.9	0.2	-0.1	0.5	-0.3	-0.2
Mouth/teeth dental problems	0.3	0.5	1.3	-0.8	1.1	0.6	0.4	0.5	-0.3	-1.2	-0.1	0.1	-0.8
Allergy	0.3	0.6	2.5	-0.5	-0.5	1.6	1.1	0.8	-0.0	-0.5	0.7	0.8	0.5
Medication: Ramipril	0.3	0.3	0.8	-0.8	-0.9	0.1	-0.1	0.8	-0.3	-0.8	-0.1	-0.3	0.8
Time employed in main current job	0.3	0.3	1.3	-0.7	-0.4	0.3	0.0	0.4	-0.2	1.1	0.2	-0.6	0.7
Asthma	0.3	0.5	1.7	-0.5	0.4	-1.0	-1.0	-0.5	-0.3	-0.1	-0.7	-1.3	-0.6
High blood pressure (siblings)	0.3	0.4	1.3	-0.1	-0.2	-0.5	-0.2	0.9	0.7	0.9	0.6	0.4	1.1
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.0	-0.0	0.1	-1.0	-0.9	-0.5	-0.4	-0.4	-0.6	-0.4	0.8
Comparative height size at age 10	0.3	1.6	6.1	-0.3	-0.6	-2.2	-1.6	-2.5	-0.2	0.8	-0.8	0.8	0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	-0.0	-0.5	-0.8	-0.7	-0.4	-0.5	-0.2	-0.8	-0.8	-1.0
Friendships satisfaction	0.3	0.4	1.0	-0.4	0.4	0.1	-0.4	1.0	-0.6	-0.8	-0.2	0.9	0.7
Asthma (self-reported)	0.3	0.5	1.5	-0.3	0.6	-0.9	-0.9	-0.5	-0.4	-0.1	-0.8	-1.2	-0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.2	0.6	1.5	-0.3	0.0	-0.2	0.2	0.2	0.0	0.0	-1.0
Unable to work because of sickness or disability	0.3	0.4	1.4	-1.2	-1.1	0.6	0.5	0.7	-0.1	-0.2	0.3	-0.3	0.7
Vascular/heart problems diagnosed by doctor	0.3	0.8	5.0	0.4	0.1	-0.0	-0.2	-0.1	-1.1	-1.1	-0.9	-0.2	-2.2
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	-1.0	0.2	-0.6	-0.6	-0.3	-0.1	-0.3	-0.3	-1.1	0.7
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	-0.4	-0.0	0.1	0.4	-0.8	0.4	-0.1	0.2	-0.3	-0.9
HDL Cholesterol	0.2	0.4	1.0	0.6	-0.5	0.7	0.5	0.7	-0.4	-0.6	0.1	1.0	-0.6
Lupus	0.2	0.4	1.3	-0.1	0.4	-1.1	-0.7	-0.4	0.4	0.8	-0.2	-0.8	0.5
Blood Platelet Count	0.2	1.8	3.8	1.3	1.0	-1.1	-1.6	1.5	-2.0	-1.2	-1.5	-0.8	-0.8
Blood White Count	0.2	1.8	7.7	-2.2	-2.8	-0.4	-0.1	1.7	0.4	-1.4	0.2	-0.1	0.3
Tanning	0.2	2.2	6.7	-0.1	0.2	2.6	2.4	0.6	1.2	0.8	1.9	0.9	1.6
Hand grip strength (right)	0.2	0.7	1.3	0.0	-0.4	-1.1	-0.9	-1.2	-0.7	-0.6	-1.1	0.2	-1.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.7	-0.3	0.5	-0.5	-0.7	-0.6	-0.3	0.4	-0.4	0.0	0.9
Chronic bronchitis/emphysema (father)	0.2	0.2	0.8	0.6	-0.0	0.4	0.1	0.7	-0.2	-0.9	-0.1	0.1	-0.0
High blood pressure (mother)	0.2	0.3	1.8	0.6	-0.0	0.1	-0.0	0.2	0.4	0.9	0.4	0.1	1.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	-0.1	-0.1	1.1	0.6	1.0	-0.4	-0.1	0.2	-0.4	-0.3
Number of live births	0.2	0.2	1.3	-0.8	-1.1	0.2	0.1	0.3	-0.2	-0.3	0.0	-0.4	-0.0
Pulse wave Arterial Stiffness index	0.2	0.2	1.1	-0.4	-0.2	0.0	-0.1	-1.1	-0.1	0.6	0.1	-0.8	0.4
Exposure to tobacco smoke at home	0.2	0.2	1.2	0.4	0.2	-0.2	0.0	-1.1	0.4	0.3	0.0	0.8	0.3
Wheeze or whistling in the chest in last year	0.2	0.4	1.0	-0.1	-0.5	0.8	1.0	0.7	0.8	0.2	0.9	0.2	0.4
Pulse wave peak to peak time	0.2	0.3	0.9	0.7	0.3	0.2	0.3	0.9	0.2	-0.4	0.0	1.0	-0.4
Migraine (self-reported)	0.2	0.3	1.8	-0.1	-0.1	0.6	0.1	1.4	-0.4	-0.2	0.1	0.6	0.1
Medication: Seretide 50 evohaler	0.2	0.3	0.9	0.2	0.2	-0.7	-0.0	-0.4	1.0	0.1	0.3	1.0	0.2
Chest pain or discomfort	0.2	0.2	0.6	-0.8	0.6	-0.7	-0.5	-0.1	-0.0	-0.6	-0.4	-0.3	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.3	-0.0	-0.2	0.5	0.8	1.2	0.4	-0.1	0.6	0.3	-0.0
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.2	0.1	0.3	0.2	0.2	1.1	-0.1	-0.5	-0.1	-0.3	-0.9
Average weekly champagne plus white wine intake	0.2	0.3	1.5	0.1	0.7	-0.5	-0.1	-0.7	0.3	0.2	0.0	1.2	-0.1
Ever taken oral contraceptive pill	0.2	0.3	0.9	-0.7	-0.9	-0.7	-0.5	-0.1	0.3	0.0	-0.3	0.8	-0.2
Ever smoked	0.2	0.4	1.1	1.0	-0.4	-0.2	-0.2	0.1	-0.9	-0.7	-0.6	-0.8	-0.4
Alcohol drinker status: Previous	0.2	0.2	0.7	0.4	0.8	-0.8	-0.6	-0.0	-0.1	-0.5	-0.5	-0.3	0.1
Allergy or Eczema	0.1	0.3	1.6	-0.8	-1.3	-0.4	0.0	-0.0	0.7	-0.1	0.1	-0.0	-0.4
Hair Pigment	0.1	2.0	11.3	-1.5	-3.4	0.5	0.9	1.4	0.8	1.2	1.1	-0.1	0.5
Hand grip strength (left)	0.1	0.3	0.6	0.5	-0.7	-0.4	-0.2	0.2	-0.3	-0.3	-0.4	0.8	-0.7
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.5	0.5	-0.3	-1.2	-0.7	0.1	0.1	0.1	-0.5	-0.3	-0.3
Past tobacco smoking	0.1	0.2	1.3	-0.3	1.1	0.1	-0.1	0.1	0.5	0.4	0.2	0.3	0.1
Financial difficulties in last 2 years	0.1	0.2	0.8	0.5	-0.0	0.4	0.4	0.9	-0.1	0.1	0.2	0.5	-0.0
Illnesses of mother	0.1	0.2	0.5	-0.6	-0.7	-0.0	0.4	0.2	0.5	-0.4	0.3	0.1	-0.0
Pulse wave reflection index	0.1	0.2	0.3	-0.4	0.6	0.3	0.3	-0.5	0.2	0.5	0.3	0.5	0.2
Smoking status: Previous	0.1	0.1	0.4	0.1	-0.4	0.3	0.3	-0.6	-0.2	-0.2	0.1	0.2	-0.1
Medication: Bendroflumethiazide	0.1	0.2	1.1	-0.1	0.6	-0.0	0.3	-0.3	0.6	0.2	0.5	0.0	1.0
Diastolic blood pressure, automated reading	0.1	0.4	1.0	0.2	1.0	-1.0	-0.5	-0.9	0.7	0.7	0.2	-0.2	0.3

Hub : Genes

AVL9

Models

Trait associations