Hub : Genes

B4GALNT1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.093 0.0300 5.4e-06 0.061 0.046 0.052 0.051 0.050 6.1e-08 2.5e-06 5.7e-07 7.8e-07 8.5e-07
2 GTEx Artery Aorta 0.124 0.0490 7.4e-04 0.042 NA 0.034 NA 0.062 2.2e-03 NA 5.4e-03 NA 2.6e-04
3 GTEx Brain Cerebellar Hemisphere 0.347 0.1190 8.4e-03 0.075 NA 0.072 NA 0.055 5.7e-03 NA 6.7e-03 NA 1.6e-02
4 GTEx Nerve Tibial 0.115 0.0473 4.0e-03 0.063 NA 0.036 NA 0.046 3.1e-05 NA 1.4e-03 NA 3.4e-04
5 GTEx Thyroid 0.155 0.0460 5.5e-06 0.126 NA 0.103 NA 0.121 7.3e-10 NA 2.9e-08 NA 1.7e-09
6 TCGA Breast Invasive Carcinoma 0.025 0.0109 8.9e-07 0.022 0.034 0.032 NA 0.030 1.9e-05 1.3e-07 3.3e-07 NA 8.1e-07
7 TCGA Colon Adenocarcinoma 0.058 0.0390 7.4e-03 0.018 0.032 0.014 NA 0.017 2.9e-02 5.7e-03 5.1e-02 NA 3.6e-02
8 TCGA Thyroid Carcinoma 0.066 0.0440 5.9e-03 0.006 0.011 -0.001 NA 0.002 7.3e-02 2.8e-02 4.6e-01 NA 1.7e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 1.0 2.1 0.1 0.5 1.2 -0.8 -0.7 -1.3 -1.4 -1.2
Bipolar Disorder or Schizophrenia 0.7 1.8 4.4 2.1 -0.1 0.5 -1.4 -1.6 -1.2 -1.8 -0.5
Depressed Affect (Nagel 2018) 3.9 8.2 20.0 -4.5 -0.1 -1.7 3.5 3.8 2.5 2.8 1.5
Depression (Nagel 2018) 1.1 1.6 3.8 -1.7 -1.7 -0.5 1.3 1.9 1.1 0.2 -0.3
Intelligence (Savage-Jansen 2018) 1.3 4.0 9.1 -3.0 -1.4 0.2 2.3 2.5 1.2 2.0 2.0
Neuroticism (Nagel 2018) 1.5 3.4 12.6 -3.6 -2.0 0.2 2.0 2.5 0.1 0.5 0.0
Schizophrenia (2018) 0.7 1.5 6.8 2.6 -0.6 -0.2 -1.1 -1.5 -0.5 -1.1 0.2
Schizophrenia vs Biploar Disorder 1.4 1.9 8.6 2.0 -2.9 -0.0 -0.5 -0.6 -1.1 -0.9 0.1
Worry (Nagel 2018) 1.7 3.6 11.3 -0.9 -3.4 2.5 -0.3 0.3 -2.4 -1.9 -1.0
Alzheimer’s Disease (in mother) 0.4 0.5 2.4 1.5 -0.4 -0.3 -0.5 -0.5 0.1 -0.4 0.8
Alzheimer’s Disease (in father) 0.7 0.8 1.7 0.7 0.2 0.7 -0.9 -0.8 -1.1 -1.0 -1.3
Alzheimer’s Disease (including proxy) 0.5 0.7 3.5 1.9 -0.5 0.2 -0.7 -0.7 -0.4 -0.7 0.3
Crohns Disease (2017) 0.3 0.7 2.8 -0.6 -1.7 0.6 0.3 0.6 -1.0 -0.6 -0.3
Irritable Bowel Disease (IBD) 1.4 3.4 12.6 1.3 -3.5 0.7 -1.0 -0.5 -2.1 -2.3 -1.2
Ulcerative Colitis (UC) 2.1 4.0 9.2 2.3 -3.0 0.6 -1.7 -1.4 -1.9 -2.6 -1.3
Major Depression (MDD) 0.8 0.9 1.9 0.6 -1.4 1.2 -0.5 -0.2 -1.1 -1.1 -1.0
Reaction Time 1.9 3.7 7.9 2.8 0.5 2.4 -2.1 -1.9 -1.4 -1.8 -1.6
Verbal and Numeric Reasoning (VNR) 1.7 4.1 7.6 -2.8 -1.9 -0.3 2.3 2.4 1.0 1.9 2.4
Breast Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ovarian Cancer 0.6 0.8 1.8 0.4 1.2 -0.9 0.3 -0.1 1.0 1.0 1.4
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.3 0.5 1.3 -0.3 0.4 1.2 -0.7 -0.6 -0.8 -0.7 -0.5
Bipolar Disorder (2011) 0.4 0.4 1.8 -1.1 1.3 -0.2 0.3 0.2 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.6 2.2 6.2 1.3 -2.5 2.0 -1.7 -1.2 0.0 0.0 -1.4
Coronary Artery Disease (CAD) 1.2 1.4 3.0 1.3 -0.3 1.7 -1.3 -1.2 -1.1 -1.2 -0.8
Crohns Disease (2012) 0.6 1.0 4.4 -0.1 -2.1 0.9 -0.2 0.2 -1.3 -1.1 -0.3
Mean Putamen Volume 0.3 0.3 1.0 -0.5 -0.3 0.8 0.1 0.4 -0.7 -0.1 -1.0
Fasting Glucose 0.5 0.6 2.5 0.1 -1.6 0.8 -0.4 -0.3 -1.2 -0.4 0.0
HbA1C 0.3 0.3 1.0 -1.0 -0.7 0.7 0.3 0.7 -0.1 -0.3 -0.0
HDL Cholesterol 2.0 3.3 13.6 3.7 -1.2 1.4 -2.1 -2.2 0.0 0.0 -0.7
LDL Cholesterol 0.1 0.2 0.7 0.5 0.3 -0.0 -0.5 -0.6 0.0 0.0 -0.9
Lupus 1.9 2.8 4.9 -2.2 -0.5 0.1 1.9 2.0 1.5 2.2 1.6
Neuroticism (2016) 0.8 1.1 5.0 -2.2 0.4 0.4 0.8 0.8 0.9 1.2 -0.2
Primary Biliary Cirrhosis 1.3 1.8 8.8 -0.9 -3.0 0.5 0.3 1.0 -1.7 -0.8 -0.4
Rheumatoid Arthritis 2.7 3.7 14.2 1.4 -3.8 1.3 -1.1 -0.5 -2.1 -1.6 -1.8
Schizophrenia (2014) 0.6 1.3 4.6 2.1 -0.8 0.3 -0.9 -1.2 -0.8 -1.3 -0.6
Triglycerides 1.0 1.6 5.4 -2.3 1.4 -0.4 1.6 1.6 0.0 0.0 0.7
Type 2 Diabetes (T2D) (2012) 0.3 0.4 1.3 1.1 -0.0 0.9 -0.6 -0.8 0.0 0.0 -0.2
Ulcerative Colitis 4.7 6.8 16.7 2.5 -4.1 0.1 -1.9 -1.6 -3.0 -3.7 -1.4
Blood Eosinophil Count 0.0 0.2 0.7 -0.2 0.8 0.4 -0.9 -0.2 0.4 0.2 -0.4
Blood Platelet Count 3.9 44.7 102.0 -5.2 10.1 -5.9 5.2 3.3 8.1 7.5 5.9
Blood Red Count 0.4 3.7 7.7 -1.9 -2.4 -1.1 2.4 2.8 -0.6 0.8 2.2
Blood White Count 1.1 7.9 14.9 -3.7 1.4 -1.6 2.6 2.3 3.5 3.9 2.4
Heel T-Score 1.0 8.2 19.9 -4.5 0.9 -2.5 3.9 3.9 1.1 2.1 1.9
BMI 0.3 1.6 8.5 -0.2 2.9 -1.6 -0.0 -0.1 0.2 0.4 1.1
Height 1.8 34.4 83.9 0.8 -8.7 9.2 -2.9 -0.8 -6.8 -5.0 -5.9
Waist Hip Ratio (WHR) 0.7 3.3 7.3 -0.9 -2.1 2.7 -1.4 -0.6 -2.6 -1.6 -1.7
Systolic Blood Pressure 2.5 12.7 20.4 -4.0 2.7 -1.5 4.2 3.9 3.1 4.5 3.7
Smoking Status 2.3 5.5 11.8 1.4 -1.3 1.7 -2.4 -2.1 -3.1 -3.4 -2.4
Allergy or Eczema 2.1 5.5 11.4 1.4 -0.8 2.9 -3.4 -3.2 -1.7 -2.6 -1.4
Cardiovascular Disease 1.4 4.8 16.0 -0.8 4.0 -1.0 1.1 0.6 2.4 2.7 2.4
Hypothyroidism (self reported) 0.6 1.4 7.8 0.2 -2.8 1.5 0.4 0.8 -0.0 0.3 0.4
Respiratory disease 2.8 6.2 11.3 3.1 -2.1 0.6 -2.8 -2.7 -2.6 -3.4 -1.4
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.9 -1.4 -0.3 0.4 0.7 1.1 -0.4 0.3 -0.7
Lung FEV1/FVC ratio 0.8 4.1 8.1 2.2 2.7 1.1 -2.4 -2.8 -0.7 -1.8 -1.1
Lung FVC 1.7 8.8 18.7 3.3 0.1 1.8 -4.0 -4.3 -2.2 -3.3 -2.4
Neuroticism 1.2 2.8 9.7 -3.1 -2.3 1.2 1.3 1.9 -0.4 0.4 -0.4
Chronotype (morning person) 2.7 6.1 9.1 -2.6 3.0 -2.9 1.6 1.1 3.0 2.9 1.7
Hair Pigment 0.3 9.0 18.7 2.3 -4.3 1.6 -2.1 -1.5 -4.3 -4.0 -2.1
Tanning 0.2 2.3 4.9 2.2 0.6 -0.5 -1.5 -1.9 -1.1 -2.2 -1.0
Hand grip strength (left) 0.2 0.5 1.9 0.0 -1.4 0.1 -0.0 -0.1 -1.2 -0.6 0.0
Number of treatments/medications taken 0.5 0.9 3.3 -1.8 0.6 -0.5 0.9 1.1 0.3 0.9 0.5
Average weekly spirits intake 0.9 1.1 4.4 -0.0 2.1 -0.7 0.6 0.2 1.1 1.2 0.9
Sensitivity / hurt feelings 2.4 4.2 13.5 -3.7 -2.4 0.7 1.5 2.5 -1.0 -0.6 -1.9
Frequency of depressed mood in last 2 weeks 0.6 0.8 2.7 -0.7 -1.7 0.3 0.3 0.8 0.5 -0.5 -1.3
Hearing difficulty/problems: Yes 0.7 1.0 2.3 -1.0 -1.4 -0.1 1.3 1.5 0.1 0.4 1.1
Relative age of first facial hair 0.7 1.3 4.7 -0.2 2.2 -0.4 -0.8 -1.5 1.0 1.0 1.1
Other serious medical condition/disability diagnosed by doctor 2.4 3.2 6.5 1.3 -2.3 0.8 -1.4 -1.2 -2.2 -2.6 -1.8
Ever used hormone-replacement therapy (HRT) 1.5 1.9 4.0 0.9 -1.5 1.1 -1.0 -0.7 -2.0 -2.0 -1.1
Ever had hysterectomy (womb removed) 1.0 1.2 2.6 1.2 -0.9 0.4 -0.8 -0.7 -1.5 -1.6 -1.0
Systolic blood pressure, automated reading 3.0 8.7 14.0 -3.5 0.9 -1.1 3.7 3.7 2.2 3.6 3.1
Eye problems/disorders: Diabetes related eye disease 2.0 2.2 3.5 1.8 0.1 1.6 -1.7 -1.9 -1.7 -1.5 -0.4
Angina 0.7 0.9 4.8 -0.3 2.2 -0.2 -0.2 -0.4 0.8 0.9 0.8
Medication for hormone replacement therapy 0.2 0.3 0.7 -0.3 -0.8 0.2 0.4 0.7 -0.6 -0.5 -0.1
Vitamin and mineral supplements 1.4 1.9 6.9 2.6 -1.1 -0.6 -1.3 -1.4 -0.8 -1.4 -0.7
Supplements: Zinc 0.5 0.6 1.6 -1.2 0.3 -0.2 0.6 0.8 0.5 0.1 -1.3
Medication: Co-codamol 0.2 0.3 0.5 0.7 -0.6 -0.3 -0.3 -0.2 -0.5 -0.6 -0.7
Medication: Metformin 0.2 0.2 0.6 0.2 0.3 0.4 -0.4 -0.5 -0.8 -0.6 -0.5
Diabetes (father) 1.3 1.6 5.0 0.6 -0.7 2.2 -1.5 -1.0 -1.4 -1.1 -0.7
Diabetes (mother) 0.2 0.3 1.9 0.1 -0.4 1.4 -0.2 0.1 0.0 0.2 -0.6
Severe depression (siblings) 2.6 2.9 7.9 0.4 -2.8 0.8 -1.0 -0.4 -1.7 -2.4 -2.0
Pack years adult smoking proportion 0.8 1.2 4.3 2.1 0.6 0.1 -1.4 -1.7 -0.1 -0.4 -0.2
Impedance of leg (right) 0.3 1.7 6.6 -0.2 -2.6 2.5 -0.1 0.1 -0.3 0.3 -0.4
Leg fat-free mass (left) 0.4 2.0 4.1 1.2 -0.1 2.0 -1.4 -1.0 -1.9 -1.5 -1.4
Trunk fat percentage 0.3 1.1 4.3 -1.1 -0.5 2.1 0.0 0.6 -1.5 -0.0 -0.7
Hand grip strength (right) 0.3 0.9 1.4 -1.2 -0.9 -0.0 1.2 1.2 0.1 0.8 1.2
Townsend deprivation index at recruitment 0.5 0.7 1.3 1.1 -0.1 0.8 -0.9 -1.0 -0.9 -1.0 -0.1
Current tobacco smoking 0.8 1.2 3.8 1.2 0.2 0.1 -1.3 -1.3 -0.1 -1.2 -1.9
Average weekly fortified wine intake 0.3 0.4 0.9 0.4 0.7 0.2 -0.7 -0.9 0.8 0.5 0.6
Maternal smoking around birth 1.3 1.9 4.5 0.7 -1.2 0.6 -1.3 -1.3 -1.9 -2.1 -1.1
Fed-up feelings 0.8 1.5 5.1 -2.2 -0.4 0.0 1.2 1.6 1.1 1.3 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 1.0 0.3 -0.4 -0.2 -0.2 -0.0 0.7 -0.3 -1.0
Relative age voice broke 0.9 1.4 2.5 0.8 -1.0 1.1 -1.2 -1.3 -1.6 -1.4 -0.8
Taking other prescription medications 1.9 2.9 8.2 1.1 -0.8 0.9 -1.8 -1.7 -2.3 -2.9 -0.9
Age when periods started (menarche) 0.8 1.8 3.5 1.9 -0.4 1.4 -1.7 -1.8 -0.9 -0.7 1.3
Bilateral oophorectomy (both ovaries removed) 1.7 2.0 2.6 -1.5 1.2 -1.5 1.5 1.3 1.1 1.3 1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 1.8 -1.3 -0.8 -0.7 0.9 0.8 -0.7 0.1 1.4
Tinnitus: Yes, but not now, but have in the past 2.1 2.2 4.3 -1.8 1.1 0.2 1.2 1.2 1.8 2.1 1.7
Qualifications: CSEs or equivalent 0.9 1.2 2.1 0.4 -1.2 -0.1 -1.0 -0.9 -1.4 -1.5 -1.4
Serious illness, injury or assault to yourself 0.9 1.1 2.3 -0.8 0.4 -0.3 1.2 1.5 1.5 1.3 0.2
High blood pressure 0.9 2.4 7.6 -0.7 2.8 -0.6 1.1 0.9 1.3 1.8 1.9
Hayfever, allergic rhinitis or eczema 1.3 2.9 6.0 1.4 -1.1 2.0 -2.5 -2.3 -1.1 -1.9 -0.6
Multivitamins +/- minerals 1.5 2.0 3.8 -1.9 1.3 0.7 1.6 1.6 1.0 1.7 1.0
Stomach or abdominal pain in last month 0.6 0.8 1.5 -1.0 0.0 -1.2 0.9 1.0 0.8 0.6 0.9
Supplements: Glucosamine 0.7 0.9 3.8 -1.9 -0.0 1.3 0.5 0.7 0.3 0.8 0.0
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 3.0 0.6 -1.4 0.8 -1.1 -0.9 -1.5 -1.7 -1.1
Medication: Atenolol 4.4 5.5 9.9 -1.4 3.1 -1.3 1.8 1.5 3.1 3.1 2.4
Medication: Levothyroxine sodium 0.6 1.1 5.3 -0.6 -2.3 1.2 0.6 1.0 -0.0 0.3 -0.0
Sitting height 2.3 16.0 47.3 1.2 -6.9 6.1 -1.7 -0.2 -4.6 -2.9 -3.0
Chronic bronchitis/emphysema (father) 0.3 0.4 1.1 0.2 -1.0 -0.8 0.1 0.3 -0.7 -0.8 -0.4
High blood pressure (mother) 1.1 1.5 3.8 -2.0 0.0 0.1 1.3 1.7 0.5 1.5 1.1
Body mass index (BMI) 0.6 2.7 10.9 -1.1 3.3 -1.1 1.0 0.9 1.1 1.7 1.6
Impedance of leg (left) 0.5 2.3 8.8 0.7 -3.0 2.4 -0.7 -0.6 -1.1 -0.7 -0.7
Leg predicted mass (left) 0.3 1.8 3.7 1.1 0.0 1.9 -1.3 -0.9 -1.8 -1.3 -1.3
Trunk fat mass 0.3 1.2 5.4 -0.5 -0.5 2.3 -0.2 0.4 -1.7 -0.2 -0.5
Waist circumference 0.2 0.8 2.9 -0.5 0.5 1.6 -0.5 -0.1 -1.7 -0.4 -0.4
Number of incorrect matches in round 4.3 7.2 12.7 2.6 -2.5 1.5 -2.7 -2.1 -3.5 -3.6 -2.2
Past tobacco smoking 2.6 4.7 11.0 -1.5 0.1 -1.4 2.4 2.4 3.0 3.3 1.3
Alcohol usually taken with meals 1.0 1.6 3.9 -2.0 0.0 -0.6 1.4 1.5 0.9 1.3 1.4
Nervous feelings 2.1 4.0 6.7 0.8 -2.5 2.6 -1.6 -1.4 -2.6 -2.5 -1.0
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 3.3 0.3 -1.0 1.6 -1.3 -1.0 -0.9 -1.8 -1.6
Hearing difficulty/problems with background noise 0.4 0.6 1.5 -1.1 -0.9 0.2 0.8 1.2 0.2 0.2 0.9
Hair/balding pattern: Pattern 2 1.0 1.2 3.0 -1.7 0.5 -0.7 1.5 1.7 0.5 0.8 -0.3
Had menopause 0.3 0.4 1.6 0.3 -1.3 0.5 -0.2 -0.0 -0.4 -0.4 -1.0
Had other major operations 0.4 0.5 1.0 -0.2 -1.0 0.6 -0.3 -0.1 -1.0 -0.8 -0.8
Forced vital capacity (FVC) 4.9 19.1 24.2 4.3 -2.8 4.6 -4.9 -4.7 -4.8 -4.9 -3.4
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 0.6 -0.6 0.1 0.1 0.2 0.0 -0.6 -0.3 0.8
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.0 -0.8 -0.0 -1.0 0.5 0.8 0.4 -0.1 -0.0
Qualifications: None of the above 0.4 0.8 1.8 1.2 1.4 0.9 -1.0 -1.1 -0.2 -0.6 -0.5
Financial difficulties in last 2 years 0.3 0.4 1.6 0.7 0.5 -1.3 0.2 0.1 0.4 -0.4 -0.9
Mouth/teeth dental problems 0.5 0.8 2.7 0.4 0.3 0.2 0.9 1.1 1.6 1.2 0.2
Heart attack 1.6 2.1 4.8 -1.6 2.0 -0.4 1.0 0.9 1.7 2.2 0.4
Allergy 3.2 7.4 12.1 -2.8 1.9 -2.3 3.5 3.2 2.3 3.2 2.0
Pain all over the body in last month 0.4 0.4 1.4 0.0 -0.8 -1.0 0.4 0.2 0.0 0.1 1.2
Diabetes (self-reported) 0.2 0.3 1.2 0.0 -0.1 1.0 -0.3 -0.1 -1.1 -0.4 -0.3
Hayfever/allergic rhinitis (self-reported) 3.0 4.0 7.6 0.4 -2.3 1.5 -2.0 -1.6 -2.4 -2.8 -2.1
Medication: Ramipril 0.6 0.8 2.1 1.5 0.7 0.3 -1.0 -1.0 -0.8 -0.8 -0.1
Medication: Simvastatin 0.5 0.8 3.9 -0.4 2.0 0.5 -0.0 -0.4 0.7 1.1 -0.2
Fluid intelligence score 0.9 1.8 4.7 -1.4 -2.2 0.0 1.3 1.6 0.3 0.9 1.7
Illnesses of siblings 1.0 1.4 4.4 -0.3 2.1 -1.3 -0.0 -0.4 1.9 0.8 0.4
Neuroticism score 0.7 1.5 4.7 -2.2 -1.7 1.4 0.5 1.1 -0.3 -0.2 -0.8
Weight 0.3 1.3 4.8 0.5 0.2 2.2 -0.9 -0.5 -1.8 -0.8 -0.5
Impedance of arm (right) 1.5 7.1 26.4 -0.3 -5.1 3.9 -0.9 0.1 -2.6 -1.7 -2.2
Arm fat percentage (right) 0.3 1.1 2.6 -1.6 1.6 0.8 0.7 0.9 -0.1 1.2 0.6
Trunk fat-free mass 0.3 1.9 3.4 1.8 -0.3 1.8 -1.4 -1.3 -1.6 -1.3 -0.5
Hip circumference 0.1 0.4 1.1 -0.3 1.0 0.6 0.3 0.5 -0.8 0.4 0.9
Time employed in main current job 2.9 3.3 7.6 2.8 -0.5 2.2 -1.7 -1.7 -1.2 -1.9 -1.6
Alcohol intake versus 10 years previously 0.6 0.9 5.5 -0.1 2.3 -0.4 -0.1 -0.3 0.8 0.4 -0.4
Father’s age at death 1.3 1.7 2.6 1.2 -1.4 1.5 -1.3 -0.9 -1.0 -1.3 -1.6
Worrier / anxious feelings 1.2 2.3 7.2 -2.2 -2.7 1.0 0.6 1.2 -1.3 -0.5 -1.2
Frequency of tiredness / lethargy in last 2 weeks 1.5 2.4 3.8 1.1 -1.6 1.4 -1.8 -1.6 -1.0 -1.9 -1.6
Falls in the last year 1.2 1.6 3.6 0.4 -1.0 1.8 -1.0 -0.6 -1.3 -1.4 -1.9
Hair/balding pattern: Pattern 3 0.1 0.2 0.4 -0.1 0.6 -0.7 0.3 0.2 0.3 0.5 -0.2
Number of live births 0.2 0.3 0.9 -0.8 -1.0 0.8 0.1 0.4 -0.5 -0.2 0.5
Forced expiratory volume in 1-second (FEV1) 4.4 14.8 20.4 4.0 -1.6 4.0 -4.5 -4.5 -4.1 -4.3 -2.8
Pulse rate 1.0 1.7 5.8 2.4 0.7 -0.0 -1.5 -1.8 -0.5 -1.2 0.4
Happiness 1.3 1.5 3.4 -0.5 0.0 -1.4 1.1 1.1 1.7 1.2 1.8
Noisy workplace 0.6 0.8 3.6 0.3 1.9 -1.2 -0.1 -0.4 0.9 0.4 -0.1
Qualifications: A levels/AS levels or equivalent 0.2 0.5 2.9 -0.6 -1.7 0.5 0.4 0.5 -0.2 0.1 -0.7
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.5 -0.5 0.1 -0.4 0.6 0.7 0.6 0.3 0.3
Mouth/teeth dental problems: Dentures 0.3 0.4 2.0 -0.8 0.2 -1.4 0.4 0.2 -0.1 0.4 0.6
Asthma 2.7 5.4 10.4 3.0 -1.9 1.0 -2.6 -2.3 -2.1 -3.2 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.7 0.8 -0.3 1.0 -1.3 -1.3 -1.2 -0.5 -0.6
Medication: Cholesterol lowering 0.6 0.9 1.9 -0.9 1.3 -0.9 0.7 0.6 1.2 1.4 0.0
Depression (self-reported) 1.2 1.4 5.6 -0.3 -2.4 0.9 -0.2 0.2 -1.4 -1.5 -0.4
Medication: Lansoprazole 1.1 1.2 2.9 1.0 -1.4 0.8 -0.9 -0.9 -1.7 -1.2 0.0
Prospective memory result 0.5 0.6 2.5 1.1 1.6 -0.1 -0.5 -0.8 0.5 0.3 0.2
Lung cancer (father) 0.2 0.2 0.5 -0.1 0.4 0.7 -0.5 -0.6 -0.6 -0.3 -0.3
Illnesses of mother 0.5 0.7 1.5 1.2 -0.5 -0.8 -0.7 -0.8 -0.6 -0.9 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 2.9 9.4 13.1 2.9 -1.2 3.1 -3.6 -3.5 -3.3 -3.4 -2.8
Pulse wave Arterial Stiffness index 1.2 1.4 3.0 -1.4 -0.4 -0.6 1.6 1.7 0.2 0.5 1.5
Impedance of arm (left) 1.3 6.1 22.5 -1.0 -4.7 3.6 -0.4 0.6 -2.2 -1.2 -2.3
Arm fat mass (right) 0.1 0.5 1.3 -0.9 1.1 0.9 0.2 0.5 -0.6 0.5 0.2
Trunk predicted mass 0.3 1.7 3.3 1.8 -0.2 1.8 -1.3 -1.2 -1.5 -1.2 -0.5
Standing height 2.3 23.0 48.9 2.8 -6.3 7.0 -3.5 -2.3 -5.7 -4.7 -4.0
Length of working week for main job 0.9 1.0 2.7 0.2 1.6 -0.7 0.3 0.1 1.6 1.1 -0.8
Exposure to tobacco smoke at home 0.1 0.2 0.4 0.3 0.3 -0.5 -0.2 -0.0 -0.7 -0.6 -0.1
Breastfed as a baby 2.0 2.5 4.0 -2.0 0.9 -1.6 1.9 1.8 1.7 1.7 0.6
Tense / ‘highly strung’ 3.5 5.7 11.0 1.8 -2.3 3.3 -2.2 -1.7 -2.6 -2.9 -1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 3.8 -0.6 -1.9 1.1 -0.2 0.2 -1.5 -1.7 0.0
Hair/balding pattern: Pattern 4 1.0 2.4 6.3 -2.5 1.0 -0.2 1.6 1.6 1.6 1.7 1.1
Birth weight of first child 0.2 0.4 1.2 -0.4 -0.8 -0.2 -0.1 0.3 -1.1 -0.9 -0.8
Peak expiratory flow (PEF) 2.2 5.0 7.6 2.6 -0.8 2.2 -2.7 -2.7 -2.4 -2.6 -0.5
Pulse wave reflection index 0.5 0.6 1.5 -1.0 -0.7 0.4 0.9 1.2 -0.3 0.4 0.8
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.7 -0.6 -0.8 0.6 -0.3 -0.0 -0.5 -0.3 -0.7
Loud music exposure frequency 2.5 2.7 6.5 -1.3 0.2 -2.5 1.8 1.8 1.8 1.3 1.4
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.0 -1.0 0.0 -0.0 0.6 0.6 0.8 0.9 0.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 0.9 -0.2 0.4 0.9 -0.8 -0.8 -0.6 -0.3 0.2
Blood clot in the leg (DVT) 0.4 0.6 1.3 -0.8 1.0 -0.4 0.7 0.6 0.4 1.2 0.7
Medication: Paracetamol 0.2 0.4 0.8 -0.6 -0.9 -0.9 0.1 0.5 -0.3 -0.2 -0.9
Headache pain in last month 0.2 0.4 1.2 -0.0 -1.1 -0.9 -0.1 -0.1 -0.8 -0.4 -0.7
Medication for cholesterol, blood pressure or diabetes 1.2 2.0 3.3 1.1 -1.6 0.9 -1.4 -1.3 -1.3 -1.8 -1.6
Glaucoma (self-reported) 0.6 0.7 2.3 -0.4 -1.5 -1.0 0.1 0.4 -0.7 -1.0 -0.4
Gout (self-reported) 3.1 4.2 13.1 -2.4 2.0 0.0 1.7 1.4 2.4 3.6 0.7
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 3.5 0.3 -1.9 1.3 0.3 0.5 0.1 0.1 0.0
Medication: Amlodipine 1.4 2.0 3.9 -1.1 2.0 -0.9 1.3 1.4 1.5 1.4 1.3
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.9 1.7 -0.2 -1.3 -0.7 -0.9 -0.1 -0.7 0.9
Birth weight 1.6 3.5 8.0 1.7 -1.1 2.0 -1.8 -1.5 -1.7 -1.8 -2.8
Chronic bronchitis/emphysema (mother) 0.1 0.2 0.6 -0.3 -0.8 -0.1 -0.5 -0.1 -0.2 -0.5 -0.2
High blood pressure (siblings) 1.4 2.0 5.3 0.0 -2.3 2.3 -0.1 0.4 -2.0 -1.0 -0.8
Forced vital capacity (FVC), Best measure 3.3 12.0 15.9 3.0 -2.5 3.4 -3.8 -3.5 -4.0 -3.9 -3.3
Body fat percentage 0.2 0.7 2.1 -1.3 0.6 1.5 0.3 0.8 -0.8 0.6 -0.1
Leg fat percentage (right) 0.3 1.0 5.1 -0.8 2.3 0.6 0.4 0.4 0.4 1.2 0.5
Arm fat-free mass (right) 0.3 1.5 3.0 1.7 0.6 1.4 -1.4 -1.4 -1.3 -0.9 -0.5
Exposure to tobacco smoke outside home 2.4 3.2 11.1 -0.5 3.3 -1.1 0.9 0.6 2.0 2.2 1.9
Comparative body size at age 10 0.2 0.7 3.4 0.7 1.8 -0.7 -0.6 -0.8 0.2 -0.0 0.3
Number of full brothers 3.6 4.5 8.1 2.6 -1.5 0.8 -2.0 -2.1 -2.7 -2.8 -1.7
Worry too long after embarrassment 0.2 0.4 0.9 -0.7 -0.6 0.9 0.6 1.0 0.3 0.4 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 3.2 -1.7 -1.5 -0.8 1.8 1.8 0.0 0.3 1.8
Wheeze or whistling in the chest in last year 0.3 0.5 2.2 -0.0 1.5 -0.3 -0.6 -0.6 -0.3 -0.7 0.4
Number of children fathered 0.1 0.1 0.6 -0.4 -0.2 -0.8 -0.1 -0.1 0.1 -0.1 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 2.7 3.1 4.4 1.7 -0.7 1.9 -1.9 -1.6 -1.9 -2.1 -1.8
Age at first live birth 1.2 2.1 3.6 -1.7 -0.4 -0.0 1.7 1.9 1.1 1.8 1.7
Pulse wave peak to peak time 1.4 1.7 3.2 1.5 -0.0 0.9 -1.8 -1.8 -0.5 -0.8 -1.8
Health satisfaction 0.2 0.3 0.8 0.6 0.0 -0.9 0.1 0.2 -0.7 -0.7 -0.2
Shortness of breath walking on level ground 0.2 0.2 0.6 0.8 0.2 -0.1 -0.5 -0.6 -0.3 -0.4 0.4
Qualifications: College or University degree 0.2 0.7 4.0 0.1 -2.0 0.7 0.2 0.6 -0.6 -0.2 -0.8
Eye problems/disorders: None of the above 0.6 0.7 1.2 -1.1 0.8 -1.1 0.7 0.5 1.0 0.8 -0.3
Mouth/teeth dental problems: Loose teeth 6.3 7.4 12.6 3.6 -0.7 1.2 -3.4 -3.5 -2.6 -3.2 -2.2
Emphysema/chronic bronchitis 0.3 0.4 2.0 1.4 -0.5 -0.6 -0.3 -0.3 -0.3 -0.4 -0.0
Medication for pain relief, constipation, heartburn 0.1 0.1 0.3 0.0 -0.4 0.0 0.2 0.0 -0.1 -0.5 0.6
Neck or shoulder pain in last month 0.2 0.2 1.0 -1.0 0.4 -0.5 0.3 0.2 0.3 0.3 0.5
Medication: Blood pressure 2.0 3.6 7.3 -1.1 2.0 -1.5 1.8 1.5 1.7 2.3 2.7
Angina (self-reported) 0.6 0.8 4.4 -0.3 2.1 -0.0 -0.3 -0.6 0.7 0.8 0.8
Migraine (self-reported) 0.5 0.6 1.1 0.6 -0.6 -1.1 -0.6 -0.9 -0.9 -0.9 0.3
Medication: Ibuprofen 0.5 0.6 1.2 0.6 -0.8 0.9 -0.9 -0.9 -1.1 -0.3 -0.6
Medication: Allopurinol 4.7 6.3 11.8 -3.0 3.1 -0.7 2.3 1.9 2.9 3.4 1.4
Medication: Omeprazole 1.5 1.8 3.4 1.6 -1.8 1.5 -1.0 -0.6 -1.6 -1.2 -0.8
Medication: Seretide 50 evohaler 1.1 1.3 6.1 0.5 -2.5 0.3 -0.4 0.1 -1.2 -1.4 -0.5
Mean time to correctly identify matches 0.7 1.4 3.0 1.7 0.3 1.3 -1.1 -0.9 -1.0 -1.4 -1.2
Heart disease (mother) 0.4 0.5 2.9 -0.7 -0.3 1.7 0.5 0.6 -0.4 0.3 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.8 -0.0 1.7 -1.6 -0.1 -0.4 0.7 0.0 0.6
Whole body fat mass 0.1 0.6 2.8 -0.7 0.3 1.7 -0.0 0.4 -1.2 0.1 -0.3
Leg fat mass (right) 0.1 0.6 2.8 -0.4 1.7 1.1 -0.0 0.1 -0.3 0.6 0.1
Arm predicted mass (right) 0.3 1.5 3.0 1.7 0.3 1.5 -1.3 -1.2 -1.4 -1.0 -0.4
Pulse rate, automated reading 0.8 2.6 6.4 2.5 0.0 0.5 -1.6 -2.1 -1.9 -1.8 -0.4
Alcohol intake frequency. 0.4 1.0 3.3 -1.8 0.6 -0.9 1.1 1.0 0.8 0.9 -0.6
Comparative height size at age 10 1.0 5.3 11.4 1.9 -3.4 3.2 -2.0 -1.3 -2.2 -1.8 -2.0
Number of full sisters 0.4 0.5 3.0 0.1 -0.2 1.7 -0.5 -0.2 0.3 -0.1 -0.8
Suffer from ‘nerves’ 0.8 1.2 3.9 -1.1 -2.0 0.4 0.1 0.4 -1.4 -1.6 -0.3
Overall health rating 0.6 1.2 2.6 1.6 0.0 0.7 -1.1 -1.0 -0.8 -1.4 -1.2
Chest pain or discomfort 1.0 1.4 3.2 -1.6 0.7 -1.8 0.8 0.7 1.0 1.0 1.4
Had major operations 0.4 0.4 1.6 -0.3 -1.3 0.8 -0.1 0.1 -0.6 -0.2 -0.8
Age at last live birth 2.0 2.9 6.0 -1.4 0.8 -0.6 1.9 1.9 1.3 2.3 2.4
Family relationship satisfaction 4.5 5.6 7.9 -2.2 1.3 -1.9 2.6 2.8 2.6 2.8 2.4
Leg pain on walking 0.5 0.7 2.8 0.0 -1.2 0.0 -0.2 0.2 -0.6 -0.8 -1.7
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 4.2 -0.9 0.0 -2.0 1.0 0.9 0.4 1.0 1.2
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.6 -0.7 0.2 0.7 0.2 0.3 -0.6 -0.0 0.1
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.0 -0.1 -0.5 0.7 -0.7 -0.8 -1.0 -0.4 0.3
Medication: Aspirin 0.8 1.1 3.6 -0.8 1.9 0.2 0.7 0.7 1.3 1.4 -0.0
Supplements: Vitamin C 0.5 0.6 1.5 -0.9 -0.5 1.0 -0.6 -0.3 -0.7 -0.6 -1.2
Knee pain experienced in last month 0.4 0.7 3.0 -0.9 0.5 -1.7 0.2 0.2 0.7 0.4 0.6
Hypertension (Self-reported) 1.0 2.9 8.9 -0.7 3.0 -0.7 1.3 1.0 1.4 2.0 2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.1 -0.1 -0.5 1.0 -0.6 -0.3 -0.9 -0.6 0.2
Illnesses of father: Heart disease 0.2 0.3 1.1 -0.7 1.1 0.1 -0.5 -0.6 -0.2 0.2 -0.4
Illnesses of siblings: Diabetes 1.0 1.3 3.3 -0.4 -1.7 0.7 -0.6 -0.1 -1.8 -1.4 -1.0
Smoking status: Previous 1.8 2.8 7.9 0.4 -1.0 1.5 -1.3 -1.1 -2.8 -2.7 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.1 0.9 -1.0 1.4 -0.6 -0.3 -0.6 -0.6 -0.7
Whole body fat-free mass 0.4 2.1 3.6 1.8 -0.2 1.9 -1.5 -1.3 -1.9 -1.5 -1.0
Leg fat-free mass (right) 0.5 2.8 5.3 1.7 -0.3 1.8 -1.7 -1.3 -2.3 -2.0 -1.6
Arm fat percentage (left) 0.3 1.2 3.3 -1.8 1.6 0.7 0.8 1.1 -0.0 1.2 0.4
Average weekly red wine intake 0.3 0.4 2.1 0.4 -1.4 0.4 -0.2 -0.1 -0.6 -0.4 0.4
Handedness (chirality/laterality): Left-handed 1.7 2.0 5.5 2.4 -2.0 -1.0 -1.2 -1.2 -1.1 -1.2 -0.4
Mood swings 0.6 1.1 3.6 -1.9 0.3 -0.9 1.2 1.1 1.1 0.7 0.3
Loneliness, isolation 4.8 6.7 10.3 -3.2 1.2 -1.9 2.9 2.8 2.8 3.2 2.0
Long-standing illness, disability or infirmity 1.1 1.7 5.7 0.2 -2.4 -1.2 -0.0 0.3 -1.4 -2.0 -0.8
Ever had bowel cancer screening 0.6 0.8 2.8 -1.7 -0.9 -0.7 0.8 1.0 0.3 0.3 -0.4
Diabetes diagnosed by doctor 0.2 0.3 1.1 0.3 0.5 1.1 -0.5 -0.3 -0.7 -0.3 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 3.0 1.2 -1.5 0.4 -1.3 -1.0 -1.2 -1.7 -0.9
Friendships satisfaction 1.9 2.4 4.0 -1.4 0.1 -0.3 1.6 2.0 1.8 2.0 1.9
Qualifications: nursing, teaching 0.4 0.6 1.5 0.2 -0.9 0.9 -0.6 -0.4 -1.2 -0.8 -0.8
Commuting to job workplace: Walk 0.7 0.8 1.8 1.3 0.1 0.7 -1.3 -1.3 -0.5 -0.4 -0.3
Eye problems/disorders: Cataract 0.4 0.5 1.7 -0.6 -1.0 1.3 0.3 0.7 -0.0 0.3 0.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 2.4 0.2 -0.4 1.1 -1.1 -1.2 -1.5 -1.2 -0.8
Medication for cholesterol 0.5 0.8 2.4 0.6 -1.5 -0.6 -0.7 -0.6 -0.7 -1.3 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.7 3.6 1.9 -0.6 0.3 -1.4 -1.4 -1.1 -1.6 -1.3
Back pain experienced in last month 0.4 0.6 1.8 -0.2 -1.4 -0.7 0.3 0.2 -1.0 -0.6 1.0
Mineral and other dietary supplements 3.3 4.5 14.3 3.8 -0.8 -0.0 -2.3 -2.4 -1.4 -2.4 -1.3
Breast cancer (self-reported) 0.2 0.3 1.4 -0.3 -0.3 -0.0 0.4 0.5 0.1 0.1 1.2
Asthma (self-reported) 2.4 4.8 9.9 2.9 -1.8 0.7 -2.4 -2.2 -2.0 -3.1 -1.1
Osteoporosis (self-reported) 1.5 1.9 2.7 1.7 -1.5 1.2 -1.5 -1.4 -1.4 -1.4 -0.6
Osteoarthritis (self-reported) 0.8 1.0 1.4 1.2 -1.1 0.6 -0.9 -1.0 -1.1 -1.1 -0.8
Medication: Aspirin 0.4 0.5 1.4 -0.4 1.2 0.7 0.4 0.4 0.9 1.1 -0.1
Medication: Gliclazide 0.4 0.5 1.2 -1.0 1.0 -0.5 0.2 0.1 -0.5 0.1 1.1
Illnesses of father: None of the above (group 1) 0.7 0.8 2.1 0.7 0.3 -1.1 0.6 0.3 1.5 1.0 1.1
Smoking status: Current 0.6 1.0 1.8 1.3 0.4 -0.1 -1.3 -1.4 -0.1 -1.0 -1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.5 5.2 12.6 3.0 0.8 0.6 -3.2 -3.5 -1.5 -2.0 -1.8
Whole body water mass 0.4 2.1 3.4 1.7 -0.1 1.8 -1.5 -1.3 -1.8 -1.5 -1.0
Leg predicted mass (right) 0.5 2.7 5.1 1.6 -0.2 1.8 -1.7 -1.3 -2.2 -1.9 -1.5
Arm fat mass (left) 0.2 0.8 2.1 -1.2 1.4 0.8 0.5 0.8 -0.3 0.9 0.3
Number of self-reported non-cancer illnesses 0.4 0.6 1.9 -1.1 -1.4 -0.6 0.7 0.9 -0.3 -0.0 0.3
Average weekly champagne plus white wine intake 1.2 1.7 4.0 -1.9 -1.7 -0.0 1.4 2.0 0.2 0.9 0.2
Miserableness 0.5 0.8 3.5 -1.9 -0.4 -0.1 0.6 0.9 0.5 0.3 -1.1
Guilty feelings 1.0 1.6 6.4 -2.5 -1.4 0.6 1.0 1.5 -0.0 0.7 0.3
Wears glasses or contact lenses 3.0 3.4 5.3 1.9 -0.5 2.1 -2.3 -2.3 -1.9 -2.1 -1.0
Ever taken oral contraceptive pill 0.4 0.5 1.6 0.4 -1.0 0.6 -0.2 0.0 -0.8 -1.3 -0.3
Hearing aid user 0.6 0.6 1.9 -0.7 -0.9 -0.1 1.2 1.4 0.5 0.4 -0.3
Mother’s age at death 1.8 2.3 3.6 -1.8 1.0 -1.9 1.6 1.5 1.3 1.4 1.4
Financial situation satisfaction 1.4 1.8 5.2 -0.7 0.2 -2.3 1.3 1.5 1.3 1.1 1.3
Tinnitus: Yes, now most or all of the time 0.4 0.5 2.6 -0.0 -0.2 -1.6 0.5 0.4 0.3 -0.3 -0.6
Commuting to job workplace: Public transport 0.4 0.5 2.3 -0.3 -1.5 0.8 0.3 0.6 0.1 0.5 0.6
Eye problems/disorders: Glaucoma 0.5 0.6 1.6 -0.0 -1.3 -0.1 -0.3 0.0 -0.9 -1.2 -1.1
Medication: Blood pressure 0.8 1.6 6.7 -0.6 2.6 0.6 0.7 0.6 1.2 1.5 0.7
Pain type(s) experienced in last month: Hip pain 0.4 0.4 0.8 0.1 -0.9 0.3 -0.6 -0.4 -0.8 -0.9 -0.8
Supplements: Fish oil (including cod liver oil) 3.3 4.3 10.6 -3.3 1.6 -0.2 2.3 2.3 1.6 2.6 1.2
High cholesterol (Self-reported) 0.6 1.1 3.6 -0.6 1.9 0.0 0.3 -0.1 1.1 1.8 0.2
Medication: Bendroflumethiazide 0.4 0.7 2.0 1.0 1.4 0.6 -0.8 -0.8 -0.4 -0.7 -0.1
Medication: Paracetamol 0.7 1.0 2.0 -1.4 -1.1 -0.9 1.0 1.4 0.3 0.8 -0.5
Medication: Lisinopril 1.5 2.0 5.4 -1.5 2.3 -0.2 1.0 0.9 1.1 1.6 1.6
Medication: Atorvastatin 1.3 1.6 3.0 -1.1 0.4 -1.3 1.2 1.2 1.6 1.7 1.4
Illnesses of father: High blood pressure 0.5 0.6 2.0 -0.1 -1.1 0.8 -0.4 -0.2 -1.4 -0.9 0.1
Alcohol drinker status: Never 0.1 0.1 0.3 -0.5 -0.6 0.3 0.4 0.4 0.1 -0.2 -0.2
Ever smoked 2.1 3.7 8.7 1.5 0.2 0.7 -2.3 -2.5 -2.4 -3.0 -1.1
Basal metabolic rate 0.4 2.2 4.1 1.6 -0.1 2.0 -1.5 -1.2 -2.0 -1.4 -1.0
Leg fat percentage (left) 0.2 0.7 4.1 -0.3 2.0 0.5 0.1 0.1 -0.1 0.7 0.4
Arm fat-free mass (left) 0.3 1.5 2.9 1.6 0.0 1.4 -1.2 -1.1 -1.7 -1.1 -0.3
Number of operations (self-reported) 1.4 2.0 5.2 -2.3 -1.3 -0.3 1.9 2.1 0.5 1.0 0.5
Average weekly beer plus cider intake 0.6 0.8 1.7 0.7 0.2 0.1 -1.2 -1.3 -1.2 -0.9 -0.8
Irritability 0.4 0.7 2.1 -0.0 0.9 1.4 -0.9 -1.1 0.1 -0.1 -0.9
Risk taking 1.8 2.7 6.4 -2.2 2.5 0.1 1.2 1.2 1.4 1.8 1.5
Ever had prostate specific antigen (PSA) test 2.0 2.3 4.1 -1.2 -0.5 -1.9 1.9 2.0 1.3 1.6 0.8
Fractured/broken bones in last 5 years 3.5 4.6 8.3 2.9 -0.3 2.1 -2.5 -2.7 -1.4 -2.1 -1.9
Age started oral contraceptive pill 0.9 1.1 2.0 -1.3 1.4 1.1 0.8 0.8 0.3 1.4 0.9
Diastolic blood pressure, automated reading 0.8 2.4 5.0 -2.0 -0.4 -0.9 2.2 2.2 0.2 1.3 1.7
Ever depressed for a whole week 0.9 1.1 2.4 -1.5 0.6 -1.4 0.9 1.0 1.1 0.6 0.5
Unable to work because of sickness or disability 1.1 1.5 2.2 1.4 -1.2 1.0 -1.1 -0.8 -1.3 -1.5 -1.3
Commuting to job workplace: Cycle 1.3 1.6 3.0 -0.6 1.6 -1.6 0.9 0.6 1.7 1.5 0.9
Myopia 0.7 1.1 3.2 -1.2 -1.8 0.6 0.6 1.0 -0.2 0.1 -1.4
Vascular/heart problems diagnosed by doctor 1.4 3.8 9.7 1.1 -3.1 1.0 -1.5 -1.2 -1.9 -2.4 -2.4
Cholesterol lowering medication 1.9 2.8 6.8 -1.8 2.0 -0.3 1.5 1.2 1.9 2.6 1.2
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 2.5 1.6 -0.9 1.5 -1.2 -0.8 -1.1 -1.1 -0.7
Pain experienced in last month 0.7 1.2 2.4 1.4 0.5 1.5 -1.0 -1.0 -0.3 -0.8 -1.6
Supplements: Calcium 0.3 0.4 0.8 0.3 -0.7 0.1 -0.5 -0.3 -0.9 -0.8 -0.8
Basal cell carcinoma (self-reported) 0.4 0.4 1.4 -1.0 -0.3 -0.2 0.4 0.8 0.1 -0.1 -1.2
Heart attack/myocardial infarction (self-reported) 1.4 1.8 4.3 -1.5 1.8 -0.3 1.0 1.0 1.6 2.1 0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.3 -0.7 1.0 -0.1 0.5 0.4 0.4 1.1 0.6
Heart disease (siblings) 0.4 0.4 1.6 0.0 -0.7 0.2 -0.2 0.0 -1.3 -0.9 -0.7
Alcohol drinker status: Previous 0.9 1.0 2.2 0.9 -1.0 1.2 -1.1 -1.1 -1.5 -0.8 -0.2
Pack years of smoking 0.7 1.0 3.3 1.8 0.5 -0.0 -1.2 -1.6 -0.2 -0.4 -0.3
Impedance of whole body 1.1 5.4 22.5 -0.3 -4.7 3.4 -0.5 0.2 -2.1 -1.2 -1.7
Leg fat mass (left) 0.1 0.5 2.5 -0.1 1.6 1.1 -0.3 -0.1 -0.7 0.2 0.1
Arm predicted mass (left) 0.3 1.7 3.4 1.8 0.4 1.6 -1.4 -1.4 -1.6 -1.1 -0.3