TWAS hub - BEND4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0190	2.1e-04	0.011	0.014	0.000	0.014	0.006	1.3e-02	6.2e-03	2.8e-01	0.0069	5.5e-02
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0588	0.0284	3.9e-05	0.072	0.034	0.061	NA	0.067	1.6e-08	8.9e-05	1.8e-07	NA	4.7e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Mineral and other dietary supplements	15.4	20.7	24.9	4.1	5.0
Major Depression (MDD)	13.7	16.6	20.0	-4.5	-3.6
Vitamin and mineral supplements	12.9	17.5	21.4	3.7	4.6
Supplements: Glucosamine	12.4	16.2	22.7	-3.1	-4.8
Supplements: Fish oil (including cod liver oil)	11.9	15.6	17.1	-3.8	-4.1
Supplements: Zinc	10.4	11.3	17.5	-2.3	-4.2
Neuroticism (Nagel 2018)	10.2	23.9	24.7	-4.8	-5.0
Neuroticism score	9.9	20.6	22.9	-4.8	-4.3
Alcohol usually taken with meals	9.8	15.9	18.9	-3.6	-4.3
Allergy or Eczema	9.5	25.0	25.4	-5.0	-5.0
Neuroticism	9.5	22.9	26.8	-5.2	-4.4
Frequency of tiredness / lethargy in last 2 weeks	9.1	14.8	16.0	-3.7	-4.0
Mood swings	7.7	13.9	13.9	-3.7	-3.7
Worry (Nagel 2018)	7.6	16.0	17.4	-3.8	-4.2
Depressed Affect (Nagel 2018)	7.2	15.1	15.8	-4.0	-3.8
Hayfever, allergic rhinitis or eczema	7.1	15.4	16.6	-4.1	-3.8
Multivitamins +/- minerals	7.1	9.0	11.6	-2.5	-3.4
Frequency of depressed mood in last 2 weeks	6.9	9.6	9.8	-3.1	-3.1
Illness, injury, bereavement, stress in last 2 years	6.9	8.4	9.1	3.0	2.8
Depression (Nagel 2018)	6.3	9.4	11.6	-3.4	-2.7
Supplements: Vitamin C	6.3	7.5	10.2	-2.2	-3.2
Miserableness	6.0	10.4	11.9	-3.5	-3.0
Illnesses of mother	5.9	7.3	10.7	2.0	3.3
Worrier / anxious feelings	5.8	11.0	14.4	-2.7	-3.8
Frequency of unenthusiasm / disinterest in last 2 weeks	5.7	7.6	11.5	-3.4	-1.9
High blood pressure (mother)	5.4	7.6	7.7	-2.8	-2.7
Guilty feelings	5.4	8.1	8.5	-2.8	-2.9
Nervous feelings	5.3	9.9	11.0	-3.3	-3.0
Allergy	5.3	12.3	12.7	3.6	3.4
Long-standing illness, disability or infirmity	5.3	8.0	8.3	-2.8	-2.9
Ever highly irritable/argumentative for 2 days	5.0	6.1	10.9	-1.1	-3.3
Comparative body size at age 10	5.0	13.8	21.1	2.6	4.6
Tense / ‘highly strung’	4.9	8.1	8.8	-3.0	-2.7
Medication: Allopurinol	4.9	6.5	6.9	2.5	2.6
Serious illness, injury or assault to yourself	4.8	5.8	6.9	-2.6	-2.2
Average weekly red wine intake	4.7	7.0	8.1	-2.8	-2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	4.6	7.0	8.9	-2.3	-3.0
Number of children fathered	4.5	5.1	6.7	1.9	2.6
Medication: Gliclazide	4.5	5.1	5.6	2.4	2.1
Medication: Seretide 50 evohaler	4.4	5.0	5.7	-2.4	-2.1
Supplements: Calcium	4.4	4.8	6.5	-1.8	-2.6
Serious illness, injury or assault of a close relative in last 2 years	4.3	4.9	5.6	-2.4	-2.1
Worry too long after embarrassment	4.3	7.3	7.5	-2.7	-2.7
Loneliness, isolation	4.3	6.0	6.4	-2.4	-2.5
Prospective memory result	4.1	5.0	5.4	-2.1	-2.3
Ever unenthusiastic/disinterested for a whole week	4.0	4.9	6.8	-1.7	-2.6
Other serious medical condition/disability diagnosed by doctor	3.9	5.1	6.2	-2.0	-2.5
Trunk fat percentage	3.9	15.6	18.0	4.2	3.6
Had other major operations	3.9	4.8	6.3	-1.8	-2.5
Headache pain in last month	3.9	6.6	7.9	-2.3	-2.8
Wears glasses or contact lenses	3.9	4.5	8.4	-2.9	-0.8
Frequency of tenseness / restlessness in last 2 weeks	3.8	6.0	6.3	-2.4	-2.5
Pack years adult smoking proportion	3.7	5.7	8.4	1.7	2.9
Body fat percentage	3.7	14.7	17.6	4.2	3.4
Seen a psychiatrist for nerves, anxiety, tension or depression	3.7	4.8	5.0	-2.2	-2.1
Medication: Atorvastatin	3.7	4.6	5.2	2.3	2.0
Breast cancer (self-reported)	3.6	4.3	5.9	-1.7	-2.4
Impedance of whole body	3.6	18.4	24.7	5.0	3.5
Leg fat percentage (right)	3.5	12.8	15.2	3.9	3.2
Family relationship satisfaction	3.5	4.3	6.0	-1.6	-2.5
Sensitivity / hurt feelings	3.4	5.8	8.3	-2.9	-1.8
Impedance of leg (left)	3.4	16.7	24.1	4.9	3.0
Impedance of leg (right)	3.3	16.0	21.7	4.7	3.2
Leg fat percentage (left)	3.3	11.8	15.3	3.9	2.9
Wheeze or whistling in the chest in last year	3.2	5.8	7.3	-2.7	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	3.2	3.4	4.9	-1.4	-2.2
Noisy workplace	3.1	3.9	6.2	-1.3	-2.5
Pack years of smoking	3.1	4.5	7.6	1.2	2.8
Reaction Time	3.0	5.7	7.5	-2.0	-2.7
Ever smoked	3.0	5.3	6.4	-2.0	-2.5
Number of treatments/medications taken	2.9	5.2	7.5	-2.7	-1.7
Trunk fat mass	2.9	12.3	14.5	3.8	3.2
Mean time to correctly identify matches	2.9	5.5	6.2	-2.5	-2.2
Ever depressed for a whole week	2.9	3.6	4.4	-1.7	-2.1
Gout (self-reported)	2.8	3.8	5.6	1.4	2.4
Age at last live birth	2.8	4.1	5.1	-1.8	-2.3
Medication: Paracetamol	2.8	4.4	4.5	-2.1	-2.1
Bipolar Disorder or Schizophrenia	2.7	6.5	7.9	-2.3	-2.8
Fasting Glucose	2.7	3.2	4.8	1.3	2.2
Time employed in main current job	2.7	3.1	4.0	-1.5	-2.0
Medication: Lansoprazole	2.7	3.1	5.2	-2.3	-0.9
Chest pain or discomfort	2.7	3.8	4.0	-1.9	-2.0
Commuting to job workplace: Cycle	2.6	3.2	3.7	-1.6	-1.9
HbA1C	2.5	2.7	4.0	-2.0	-1.2
Impedance of arm (right)	2.5	11.8	13.5	3.7	3.2
Qualifications: A levels/AS levels or equivalent	2.5	5.6	6.9	-2.1	-2.6
Impedance of arm (left)	2.5	11.4	14.4	3.8	2.9
Qualifications: nursing, teaching	2.5	3.8	5.7	-1.4	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.3	8.2	-2.9	-1.5
Number of self-reported non-cancer illnesses	2.5	4.4	7.2	-2.7	-1.3
Average weekly beer plus cider intake	2.5	3.5	5.9	1.1	2.4
Schizophrenia (2018)	2.4	5.1	5.6	-2.1	-2.4
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	3.4	-1.6	-1.8
Whole body fat mass	2.4	10.0	11.5	3.4	2.9
Body Mass Index (BMI) (2010)	2.3	3.1	3.6	1.6	1.9
Neuroticism (2016)	2.3	3.3	6.5	-2.5	-0.4
Hearing difficulty/problems with background noise	2.3	3.7	5.5	-2.3	-1.4
Health satisfaction	2.3	3.0	3.2	-1.7	-1.8
Myopia	2.3	3.4	5.3	-1.2	-2.3
Stomach or abdominal pain in last month	2.2	2.8	4.0	-1.2	-2.0
Medication for cholesterol, blood pressure or diabetes	2.2	3.6	3.8	-2.0	-1.9
Medication for pain relief, constipation, heartburn	2.2	3.7	4.2	2.1	1.8
Fed-up feelings	2.1	3.8	4.5	-2.1	-1.8
Lung cancer (father)	2.1	2.4	3.3	1.2	1.8
Medication: Paracetamol	2.1	3.5	3.8	-1.8	-1.9
Medication: Blood pressure	2.1	3.7	4.0	1.8	2.0
Heart disease (mother)	2.1	2.5	2.6	-1.5	-1.6
Leg fat mass (right)	2.1	8.0	9.1	3.0	2.6
Leg fat mass (left)	2.1	8.3	10.2	3.2	2.5
Eye problems/disorders: None of the above	2.0	2.3	3.8	-1.0	-1.9
Coronary Artery Disease (CAD)	1.8	2.1	2.2	1.4	1.5
Diabetes (father)	1.8	2.2	2.2	-1.5	-1.5
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	2.9	-1.7	-1.4
Arm fat percentage (right)	1.8	7.3	8.2	2.9	2.5
Medication: Cholesterol lowering	1.8	2.8	3.8	1.9	1.3
Alcohol intake frequency.	1.8	4.2	5.9	-2.4	-1.6
Arm fat percentage (left)	1.8	7.3	8.5	2.9	2.5
Irritability	1.8	3.0	3.7	-1.5	-1.9
Schizophrenia (2014)	1.7	3.7	5.9	-1.2	-2.4
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	3.1	-1.8	-1.5
Type 2 Diabetes (T2D) (2012)	1.6	1.9	3.6	0.3	1.9
Type 2 Diabetes (T2D) (2018)	1.6	2.9	3.3	1.8	1.6
Happiness	1.6	1.9	3.0	-0.9	-1.7
Medication: Ventolin 100micrograms inhaler	1.6	2.1	2.7	-1.7	-1.2
Pulse rate, automated reading	1.6	5.2	7.4	-2.7	-1.7
Alzheimer’s Disease (in father)	1.5	1.6	3.1	-1.8	-0.4
Hearing difficulty/problems: Yes	1.5	2.2	4.1	-2.0	-0.6
Medication: Atenolol	1.5	1.9	3.3	0.7	1.8
Eye problems/disorders: Glaucoma	1.5	1.8	2.5	1.1	1.6
Hip circumference	1.4	5.9	7.0	2.6	2.2
Alcohol intake versus 10 years previously	1.4	2.1	4.2	0.0	-2.1
Mouth/teeth dental problems: Dentures	1.4	2.4	3.2	1.2	1.8
Suffer from ‘nerves’	1.4	2.2	2.6	-1.3	-1.6
Handedness (chirality/laterality): Left-handed	1.4	1.7	2.2	-1.5	-1.1
Arm fat mass (left)	1.4	5.9	6.3	2.5	2.3
Pain experienced in last month	1.4	2.4	2.4	1.5	1.6
Age at First Birth	1.3	1.9	3.5	-1.9	-0.6
Lung FEV1/FVC ratio	1.3	6.6	8.3	-2.9	-2.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	5.4	-1.7	-2.3
Arm fat mass (right)	1.3	5.4	5.6	2.4	2.3
Number of full brothers	1.3	1.6	2.3	-1.5	-0.9
Number of operations (self-reported)	1.3	1.9	2.2	-1.5	-1.2
Schizophrenia vs Biploar Disorder	1.2	1.5	2.4	-0.8	-1.5
Lung FVC	1.2	6.1	6.8	-2.6	-2.3
Diabetes (self-reported)	1.2	1.9	2.2	1.5	1.3
Breastfed as a baby	1.2	1.5	2.2	-0.9	-1.5
Overall health rating	1.2	2.6	3.3	-1.8	-1.3
Asthma (self-reported)	1.2	2.3	2.4	-1.5	-1.5
Illnesses of father: High blood pressure	1.2	1.5	1.5	-1.2	-1.2
Bipolar Disorder (2018)	1.1	1.7	2.4	-1.0	-1.5
Alzheimer’s Disease (including proxy)	1.1	1.6	2.7	-1.7	-0.7
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	1.6	1.0	1.3
Medication: Metformin	1.1	1.6	1.6	1.2	1.3
Asthma	1.1	2.2	2.5	-1.6	-1.4
Back pain experienced in last month	1.1	1.6	2.1	-1.5	-1.0
Intelligence (Savage-Jansen 2018)	1.0	3.1	4.0	-1.5	-2.0
Verbal and Numeric Reasoning (VNR)	1.0	2.4	2.4	-1.5	-1.6
Respiratory disease	1.0	2.3	3.1	-1.2	-1.8
Sitting height	1.0	7.1	8.3	2.5	2.9
Qualifications: None of the above	1.0	2.2	4.0	0.7	2.0
Length of working week for main job	1.0	1.1	1.7	-0.7	-1.3
Hair/balding pattern: Pattern 4	1.0	2.3	2.5	1.5	1.6
Qualifications: College or University degree	1.0	3.2	3.6	-1.7	-1.9
Diabetes diagnosed by doctor	1.0	1.6	1.7	1.2	1.3
Medication: Aspirin	1.0	1.2	2.2	0.5	1.5
Tinnitus: Yes, now most or all of the time	1.0	1.1	2.0	-0.5	-1.4
Fractured/broken bones in last 5 years	1.0	1.3	1.8	1.3	0.9
Heart disease (siblings)	1.0	1.2	1.9	-0.7	-1.4
Waist Hip Ratio (WHR)	0.9	4.0	4.2	-2.0	-1.9
Maternal smoking around birth	0.9	1.3	1.3	1.2	1.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	1.8	-0.6	-1.4
Pulse wave peak to peak time	0.9	1.1	1.5	1.2	0.8
Medication: Ibuprofen	0.9	1.0	1.3	-0.9	-1.1
Prostate Cancer	0.8	1.1	1.2	-1.0	-1.1
Mean Putamen Volume	0.8	0.9	1.5	1.2	0.6
Rheumatoid Arthritis	0.8	1.1	1.8	0.6	1.4
Average weekly fortified wine intake	0.8	0.9	1.2	-1.1	-0.8
Taking other prescription medications	0.8	1.3	2.0	-1.4	-0.8
High blood pressure	0.8	2.3	4.2	0.6	2.1
Weight	0.8	3.9	4.6	2.1	1.8
Exposure to tobacco smoke at home	0.8	0.9	1.6	-0.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	3.0	-1.7	-0.5
Hypertension (Self-reported)	0.8	2.2	4.2	0.5	2.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.4	0.6	1.2
Shortness of breath walking on level ground	0.7	0.8	1.4	-1.2	-0.5
Medication: Aspirin	0.7	1.0	1.9	0.2	1.4
Eye problems/disorders: Cataract	0.7	0.9	1.7	-1.3	-0.2
Average weekly champagne plus white wine intake	0.7	1.0	1.6	-0.6	-1.3
Financial situation satisfaction	0.7	0.9	1.8	1.4	-0.1
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.6	-1.3	-0.2
Unable to work because of sickness or disability	0.7	0.9	1.7	-0.2	-1.3
Vascular/heart problems diagnosed by doctor	0.7	1.9	3.6	-0.4	-1.9
Alcohol drinker status: Previous	0.7	0.8	1.5	-0.2	1.2
Lupus	0.6	0.8	1.7	-0.2	-1.3
Primary Biliary Cirrhosis	0.6	0.8	1.3	1.1	0.6
Height	0.6	11.3	12.5	3.5	3.2
Medication: Co-codamol	0.6	0.7	0.7	-0.8	-0.8
Pulse rate	0.6	1.0	1.6	-1.2	-0.6
Cardiovascular Disease	0.5	1.7	2.8	0.8	1.7
Relative age of first facial hair	0.5	1.1	1.8	0.6	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.2	1.0	1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.6	-0.6	-0.8
Mouth/teeth dental problems	0.5	0.7	0.9	-1.0	-0.7
Father’s age at death	0.5	0.7	1.4	-0.2	-1.2
Falls in the last year	0.5	0.6	0.7	0.7	0.8
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	2.2	-1.0	-1.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.0	-1.0	-0.5
Exposure to tobacco smoke outside home	0.5	0.7	0.8	0.8	0.9
Illnesses of father: Heart disease	0.5	0.7	1.3	-0.5	-1.1
Friendships satisfaction	0.5	0.6	0.8	-0.6	-0.9
High cholesterol (Self-reported)	0.5	0.9	1.8	0.1	1.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.9	-0.5	-0.9
Ulcerative Colitis	0.4	0.6	0.7	0.7	0.9
Hypothyroidism (self reported)	0.4	0.8	1.7	-1.3	-0.0
Ever had hysterectomy (womb removed)	0.4	0.4	0.8	-0.1	0.9
Angina	0.4	0.5	1.0	-1.0	0.3
Current tobacco smoking	0.4	0.6	0.6	-0.7	0.8
Medication: Levothyroxine sodium	0.4	0.6	1.0	-1.0	-0.6
Had menopause	0.4	0.5	0.8	-0.9	0.4
Financial difficulties in last 2 years	0.4	0.6	0.8	-0.9	-0.6
Heart attack	0.4	0.5	0.8	-0.5	-0.9
Standing height	0.4	4.1	6.1	2.5	1.4
Loud music exposure frequency	0.4	0.5	0.9	-0.0	-1.0
Forced vital capacity (FVC), Best measure	0.4	1.4	2.2	-0.8	-1.5
Migraine (self-reported)	0.4	0.5	0.5	-0.7	-0.7
Comparative height size at age 10	0.4	2.3	2.5	1.6	1.4
Number of full sisters	0.4	0.5	0.9	1.0	-0.1
Had major operations	0.4	0.5	0.9	-1.0	-0.3
Leg pain on walking	0.4	0.5	0.9	0.2	-1.0
Medication for cholesterol	0.4	0.6	1.0	-0.3	-1.0
Medication: Lisinopril	0.4	0.5	0.6	0.6	0.8
Alcohol drinker status: Never	0.4	0.5	1.0	-1.0	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.9	0.3	1.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.6	0.6	0.8
Breast Cancer	0.3	0.7	1.4	1.2	0.1
Systolic Blood Pressure	0.3	1.4	2.4	0.7	1.5
Body mass index (BMI)	0.3	1.3	1.4	1.1	1.2
Pain all over the body in last month	0.3	0.3	0.6	0.7	-0.4
Depression (self-reported)	0.3	0.4	0.6	0.8	-0.4
Birth weight of first child	0.3	0.5	0.8	0.5	0.9
Peak expiratory flow (PEF)	0.3	0.7	1.2	-0.5	-1.1
High blood pressure (siblings)	0.3	0.4	0.5	-0.7	0.6
Age at first live birth	0.3	0.5	0.6	-0.7	-0.8
Angina (self-reported)	0.3	0.4	0.7	-0.8	0.3
Knee pain experienced in last month	0.3	0.5	0.9	-1.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.2	1.1	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.1	-0.1	-1.0
Smoking status: Current	0.3	0.4	0.6	-0.8	0.6
Risk taking	0.3	0.5	0.9	-1.0	-0.3
Age started oral contraceptive pill	0.3	0.3	0.7	-0.8	0.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	-0.2	-0.6
Ulcerative Colitis (UC)	0.2	0.4	0.6	0.5	0.8
Ovarian Cancer	0.2	0.3	0.4	-0.6	-0.4
Bipolar Disorder (2011)	0.2	0.2	0.2	0.4	0.5
Crohns Disease (2012)	0.2	0.4	0.7	0.3	0.9
HDL Cholesterol	0.2	0.3	0.5	0.7	-0.3
Blood Platelet Count	0.2	2.0	3.5	0.7	1.9
Blood White Count	0.2	1.3	2.4	-1.6	-0.3
BMI	0.2	0.9	1.2	1.1	0.8
Chronotype (morning person)	0.2	0.4	0.7	0.4	0.9
Medication for hormone replacement therapy	0.2	0.2	0.5	-0.2	-0.7
Severe depression (siblings)	0.2	0.2	0.4	-0.1	-0.7
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	-0.3	-0.5
Qualifications: CSEs or equivalent	0.2	0.2	0.4	0.7	-0.2
Chronic bronchitis/emphysema (father)	0.2	0.2	0.4	0.0	-0.6
Waist circumference	0.2	0.9	1.2	1.1	0.7
Forced vital capacity (FVC)	0.2	0.7	1.3	-0.2	-1.1
Illnesses of siblings	0.2	0.2	0.4	0.6	0.1
Trunk fat-free mass	0.2	1.0	1.2	-1.1	-0.8
Trunk predicted mass	0.2	0.9	1.1	-1.0	-0.8
Blood clot in the leg (DVT)	0.2	0.3	0.4	0.5	0.6
Birth weight	0.2	0.3	0.5	0.4	-0.7
Neck or shoulder pain in last month	0.2	0.2	0.4	0.6	0.2
Medication: Omeprazole	0.2	0.2	0.5	-0.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.6	0.8	0.1
Illnesses of siblings: Diabetes	0.2	0.2	0.3	0.3	-0.6
Osteoporosis (self-reported)	0.2	0.2	0.3	0.3	-0.5
Ever taken oral contraceptive pill	0.2	0.3	0.4	0.6	-0.4
Mother’s age at death	0.2	0.3	0.5	-0.7	0.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	-0.3	-0.7
Irritable Bowel Disease (IBD)	0.1	0.1	0.3	-0.1	0.5
LDL Cholesterol	0.1	0.2	0.2	0.5	-0.3
Triglycerides	0.1	0.2	0.4	-0.3	0.6
Blood Red Count	0.1	1.1	2.0	-0.5	-1.4
Heel T-Score	0.1	0.4	0.9	0.9	-0.2
Smoking Status	0.1	0.4	0.5	-0.7	-0.4
Average weekly spirits intake	0.1	0.1	0.1	0.0	0.4
Systolic blood pressure, automated reading	0.1	0.4	0.9	-0.0	0.9
Diabetes (mother)	0.1	0.2	0.2	0.4	-0.5
Hand grip strength (right)	0.1	0.3	0.6	0.8	0.1
Townsend deprivation index at recruitment	0.1	0.2	0.3	0.3	0.6
Relative age voice broke	0.1	0.2	0.4	0.1	0.6
Age when periods started (menarche)	0.1	0.1	0.2	-0.3	-0.5
Number of incorrect matches in round	0.1	0.2	0.3	-0.1	0.6
Past tobacco smoking	0.1	0.3	0.5	-0.1	0.7
Hair/balding pattern: Pattern 2	0.1	0.2	0.3	-0.1	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.3	0.5	0.5
Fluid intelligence score	0.1	0.1	0.1	-0.3	-0.3
Number of live births	0.1	0.2	0.2	0.5	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.2	0.1	-0.5
Medication: Amlodipine	0.1	0.1	0.1	0.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	0.1	0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.4	0.2
Emphysema/chronic bronchitis	0.1	0.1	0.1	0.0	-0.3
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	0.4	0.3
Smoking status: Previous	0.1	0.2	0.2	0.5	-0.4
Whole body fat-free mass	0.1	0.4	0.6	-0.8	-0.5
Commuting to job workplace: Walk	0.1	0.1	0.1	-0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.3	-0.1	-0.6
Osteoarthritis (self-reported)	0.1	0.2	0.3	-0.5	0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	0.2
Whole body water mass	0.1	0.5	0.8	-0.9	-0.5
Leg predicted mass (right)	0.1	0.3	0.4	-0.6	-0.6
Hearing aid user	0.1	0.1	0.2	-0.1	-0.4
Medication: Blood pressure	0.1	0.3	0.5	-0.7	0.2
Cholesterol lowering medication	0.1	0.1	0.2	-0.2	0.4
Basal cell carcinoma (self-reported)	0.1	0.2	0.3	-0.2	-0.5
Crohns Disease (2017)	0.0	0.1	0.1	-0.4	0.3
Blood Eosinophil Count	0.0	0.1	0.3	0.5	0.1
Hair Pigment	0.0	1.0	1.6	1.3	0.6
Tanning	0.0	0.5	1.0	1.0	0.2
Hand grip strength (left)	0.0	0.0	0.0	0.0	-0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.1	0.3	-0.1
Leg fat-free mass (left)	0.0	0.0	0.0	-0.2	0.0
Leg predicted mass (left)	0.0	0.0	0.0	-0.2	-0.0
Medication: Ramipril	0.0	0.1	0.1	0.1	0.3
Medication: Simvastatin	0.0	0.1	0.1	-0.3	-0.1
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	0.0	-0.0
Pulse wave reflection index	0.0	0.0	0.1	0.1	-0.3
Glaucoma (self-reported)	0.0	0.0	0.1	-0.0	0.3
Arm fat-free mass (right)	0.0	0.1	0.1	-0.3	-0.3
Arm predicted mass (right)	0.0	0.2	0.2	-0.4	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.0	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.1	0.3	-0.1
Leg fat-free mass (right)	0.0	0.3	0.3	-0.5	-0.5
Ever had bowel cancer screening	0.0	0.0	0.1	0.3	0.1
Commuting to job workplace: Public transport	0.0	0.0	0.1	0.0	-0.3
Medication: Bendroflumethiazide	0.0	0.1	0.1	0.1	0.3
Basal metabolic rate	0.0	0.0	0.0	0.1	0.1
Arm fat-free mass (left)	0.0	0.0	0.0	-0.2	0.1
Diastolic blood pressure, automated reading	0.0	0.0	0.0	-0.2	0.1
Arm predicted mass (left)	0.0	0.1	0.2	-0.5	-0.1

Hub : Genes

BEND4

Models

Trait associations