TWAS hub - BET1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.1460	0.0490	3.1e-03	0.102	NA	0.048	NA	0.068	2.5e-07	NA	3.7e-04	NA	2.5e-05
2	ROSMAP	Brain Pre-frontal Cortex	0.0764	0.0301	3.1e-03	0.051	0.007	0.028	0.019	0.041	3.4e-07	4.1e-02	1.3e-04	1.3e-03	4.9e-06
3	YFS	Blood	0.0711	0.0158	1.7e-12	0.069	0.034	0.063	0.053	0.068	1.1e-21	3.3e-11	8.4e-20	7.4e-17	3.7e-21
4	TCGA	Breast Invasive Carcinoma	0.0231	0.0109	2.4e-04	0.027	0.019	0.024	NA	0.022	2.8e-06	5.9e-05	9.4e-06	NA	1.7e-05
5	TCGA	Colon Adenocarcinoma	0.0750	0.0390	3.4e-03	0.042	0.011	-0.003	NA	0.011	1.8e-03	7.3e-02	4.9e-01	NA	7.5e-02
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0433	0.0179	2.0e-05	0.059	0.041	0.048	NA	0.054	3.0e-07	2.0e-05	3.8e-06	NA	9.6e-07
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0413	0.0186	8.3e-05	0.026	0.035	0.032	NA	0.038	5.4e-04	7.4e-05	1.3e-04	NA	3.7e-05
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0940	0.0440	1.4e-03	0.054	0.038	0.040	NA	0.033	5.0e-04	3.1e-03	2.3e-03	NA	5.5e-03
9	TCGA	Prostate Adenocarcinoma	0.0685	0.0245	4.0e-08	0.111	0.082	0.085	NA	0.104	1.2e-11	5.8e-09	3.1e-09	NA	5.0e-11
10	TCGA	Stomach Adenocarcinoma	0.0740	0.0430	1.9e-03	0.033	0.030	0.019	NA	0.024	2.0e-03	3.0e-03	1.5e-02	NA	7.5e-03
11	TCGA	Thyroid Carcinoma	0.0820	0.0290	5.0e-08	0.103	0.076	0.093	NA	0.098	3.4e-10	7.7e-08	2.3e-09	NA	8.2e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Prospective memory result	5.9	7.2	9.1	2.8	2.6	2.6	2.9	2.4	2.8	3.0	2.2	2.8	2.7	2.7
Serious illness, injury or assault to yourself	4.5	5.4	7.5	2.4	2.5	2.0	2.7	2.0	2.4	1.9	2.7	2.4	1.4	2.7
Commuting to job workplace: Cycle	4.4	5.3	6.3	-2.5	-2.4	-2.2	-2.4	-2.5	-2.5	-2.1	-1.6	-2.5	-2.2	-2.3
Medication: Seretide 50 evohaler	4.2	4.8	7.1	2.0	2.0	2.7	2.3	2.1	2.1	2.6	1.9	2.0	2.0	2.2
Medication: Gliclazide	3.6	4.1	6.4	2.0	2.1	1.9	2.5	1.9	2.1	2.5	0.9	2.1	1.6	2.1
Vitamin and mineral supplements	3.2	4.4	6.4	-2.5	-1.9	-2.0	-1.6	-2.3	-2.4	-2.0	-1.2	-2.5	-2.0	-2.0
Supplements: Fish oil (including cod liver oil)	3.2	4.2	5.5	2.2	2.1	2.0	2.3	2.1	2.2	1.8	1.5	2.2	1.4	2.2
Crohns Disease (2012)	2.9	4.6	8.7	1.9	2.1	2.4	1.9	2.1	2.0	2.1	3.0	1.9	1.6	2.3
Average weekly fortified wine intake	2.9	3.4	5.5	-1.7	-1.9	-2.1	-2.3	-1.5	-1.7	-1.7	-1.9	-1.7	-1.7	-2.0
Number of operations (self-reported)	2.9	4.3	5.4	2.3	2.2	1.9	1.9	2.0	2.3	1.8	1.8	2.3	1.9	2.3
Breast cancer (self-reported)	2.7	3.3	4.4	1.9	2.0	1.7	2.1	1.7	1.9	1.9	1.3	1.9	1.0	2.1
Bipolar Disorder (2018)	2.5	3.9	6.3	-1.9	-2.1	-1.9	-2.0	-1.8	-1.9	-1.8	-2.5	-1.8	-1.4	-2.3
Had other major operations	2.5	3.1	5.0	2.0	2.0	1.2	2.2	1.5	2.0	1.5	0.6	2.0	1.5	2.1
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	5.6	1.5	2.4	1.5	1.9	0.7	1.6	1.6	1.3	1.5	0.3	2.2
Medication: Co-codamol	2.4	2.8	5.4	1.7	1.7	1.8	1.6	1.8	1.8	1.1	0.6	1.7	2.3	1.8
Exposure to tobacco smoke at home	2.4	2.7	4.9	-2.0	-1.2	-1.5	-1.4	-2.2	-1.9	-1.4	-1.6	-2.0	-1.4	-1.2
Diabetes diagnosed by doctor	2.3	3.8	5.9	1.8	2.4	1.7	1.9	1.8	1.9	1.9	2.0	1.8	1.2	2.4
Shortness of breath walking on level ground	2.2	2.6	4.2	1.7	1.5	1.7	2.0	1.4	1.7	2.1	0.7	1.7	1.0	1.8
Type 2 Diabetes (T2D) (2012)	2.1	2.4	3.8	1.7	1.8	1.5	1.5	0.9	1.7	1.3	1.9	1.7	0.9	1.8
Medication: Simvastatin	2.1	3.1	4.9	1.9	1.3	1.7	1.7	2.2	1.7	1.9	1.6	1.8	1.8	1.4
Alzheimer’s Disease (in mother)	2.0	2.3	3.9	1.5	1.7	1.4	1.4	1.3	1.5	1.7	2.0	1.5	0.9	1.6
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.3	1.0	1.3	1.6	1.4	1.6	1.0	2.0	1.8	1.1	2.1	1.4
Exposure to tobacco smoke outside home	2.0	2.6	3.7	-1.9	-1.9	-1.3	-1.6	-1.8	-1.8	-1.2	-1.5	-1.8	-0.5	-1.9
Townsend deprivation index at recruitment	1.9	2.6	3.9	-1.8	-1.6	-2.0	-1.3	-1.5	-1.7	-1.2	-1.7	-1.7	-1.7	-1.5
Multivitamins +/- minerals	1.9	2.4	3.4	1.8	1.4	1.4	1.7	1.5	1.8	1.6	0.9	1.9	1.4	1.5
Medication: Ramipril	1.9	2.4	4.2	1.3	1.1	2.1	1.8	1.4	1.4	1.7	1.7	1.4	1.7	1.3
Mineral and other dietary supplements	1.9	2.5	3.1	-1.6	-1.6	-1.7	-1.8	-1.7	-1.6	-1.5	-1.1	-1.6	-1.5	-1.7
Alzheimer’s Disease (in father)	1.8	2.0	2.5	-1.3	-1.6	-1.4	-1.4	-1.3	-1.3	-1.4	-1.4	-1.3	-1.2	-1.6
Wheeze or whistling in the chest in last year	1.8	3.3	5.4	-1.7	-1.4	-2.1	-1.6	-2.1	-1.6	-2.3	-1.6	-1.8	-2.1	-1.3
Medication: Aspirin	1.8	2.4	3.8	-1.5	-1.9	-1.5	-1.8	-1.3	-1.5	-1.1	-1.5	-1.4	-1.3	-1.8
Supplements: Vitamin C	1.8	2.1	3.7	1.7	1.3	1.4	1.0	1.5	1.7	1.2	0.6	1.7	1.9	1.4
Illnesses of siblings: Diabetes	1.8	2.2	3.0	1.5	1.6	1.3	1.5	1.6	1.5	1.2	1.4	1.5	1.7	1.5
Smoking status: Previous	1.8	2.8	5.8	1.7	1.4	1.9	1.6	0.9	1.7	1.7	2.4	1.8	1.4	1.5
Pack years of smoking	1.8	2.7	5.2	-1.4	-1.7	-2.1	-1.9	-1.3	-1.5	-1.3	-2.3	-1.4	-1.0	-1.6
High blood pressure (mother)	1.7	2.4	5.4	-1.6	-1.4	-1.3	-2.3	-1.1	-1.6	-1.9	-1.2	-1.7	-1.0	-1.6
Number of treatments/medications taken	1.6	2.9	4.6	1.8	2.0	1.5	1.8	1.4	1.9	1.5	1.4	1.8	1.2	2.1
Angina	1.6	2.1	4.2	-1.2	-1.3	-1.6	-1.1	-1.7	-1.2	-1.9	-1.0	-1.3	-2.0	-1.1
Impedance of leg (right)	1.6	7.8	10.3	3.1	2.7	2.6	2.6	2.7	3.1	2.9	2.3	3.1	2.2	3.2
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	3.0	-1.7	-1.4	-1.5	-1.1	-1.4	-1.7	-1.4	-0.7	-1.7	-1.6	-1.5
Wears glasses or contact lenses	1.6	1.8	3.4	1.1	1.2	1.8	1.1	1.2	1.1	1.0	1.8	1.1	1.8	1.2
Pack years adult smoking proportion	1.5	2.2	4.5	-1.3	-1.4	-1.9	-1.7	-1.3	-1.3	-1.3	-2.1	-1.3	-1.0	-1.3
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	4.0	1.8	1.6	1.9	1.5	1.7	1.8	2.0	1.1	1.9	1.7	1.6
Angina (self-reported)	1.5	2.0	4.0	-1.1	-1.1	-1.7	-1.1	-1.6	-1.1	-2.0	-1.0	-1.2	-2.0	-0.9
Ovarian Cancer	1.4	1.9	3.0	-1.3	-1.5	-1.6	-1.7	-1.1	-1.4	-0.9	-1.2	-1.3	-1.3	-1.6
Alcohol intake versus 10 years previously	1.4	2.1	3.5	1.5	1.7	1.4	1.7	1.0	1.6	0.5	1.4	1.4	1.1	1.9
Pulse rate	1.4	2.4	10.2	1.0	0.9	1.1	1.0	2.5	1.0	1.0	-1.4	1.0	3.2	0.8
Commuting to job workplace: Car/motor vehicle	1.4	1.6	2.2	1.1	1.2	1.5	1.4	1.3	1.1	1.0	0.9	1.1	1.5	1.4
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.2	-1.3	-1.5	-1.5	-0.9	-0.8	-1.3	-0.9	-1.8	-1.2	-1.1	-1.6
Hearing difficulty/problems with background noise	1.3	2.1	3.9	1.6	1.5	1.5	1.4	0.8	1.6	1.4	2.0	1.5	0.7	1.6
Pulse rate, automated reading	1.3	4.1	27.0	-0.6	-1.1	-1.1	-0.6	1.8	-0.6	-0.8	-5.2	-0.5	3.1	-1.1
Family relationship satisfaction	1.3	1.6	2.5	-1.6	-1.5	-1.3	-1.0	-0.9	-1.6	-1.0	-1.3	-1.5	-0.4	-1.4
Depression (Nagel 2018)	1.2	1.9	3.4	1.5	1.7	1.3	1.6	0.7	1.5	0.9	1.4	1.5	0.1	1.9
Age at First Birth	1.2	1.7	2.6	-1.4	-1.4	-1.3	-1.6	-1.4	-1.4	-1.0	-1.3	-1.3	-0.7	-1.4
Past tobacco smoking	1.2	2.1	4.5	-1.5	-1.2	-1.7	-1.3	-0.7	-1.5	-1.7	-2.1	-1.5	-1.0	-1.3
Diabetes (self-reported)	1.2	1.8	3.6	1.3	1.8	0.9	1.1	1.2	1.4	1.4	1.4	1.4	0.4	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	2.4	1.2	1.4	1.4	1.3	1.2	1.3	0.5	1.2	1.1	1.4	1.5
Qualifications: College or University degree	1.2	3.9	6.9	-2.4	-2.5	-1.6	-1.9	-1.5	-2.5	-1.2	-1.5	-2.3	-0.9	-2.6
Average weekly beer plus cider intake	1.2	1.8	2.7	1.6	1.6	1.0	1.4	1.1	1.5	1.1	1.0	1.5	0.8	1.5
Impedance of whole body	1.2	6.2	8.5	2.6	2.6	2.6	2.3	2.2	2.7	2.5	2.2	2.7	2.0	2.9
Crohns Disease (2017)	1.1	2.5	3.4	1.4	1.7	1.7	1.6	1.8	1.4	1.6	1.8	1.4	1.0	1.7
Body Mass Index (BMI) (2010)	1.1	1.6	2.9	1.3	1.7	1.0	1.3	1.0	1.4	1.0	1.0	1.3	0.6	1.7
Rheumatoid Arthritis	1.1	1.5	2.2	1.2	1.1	1.4	1.3	0.8	1.2	1.3	1.5	1.2	1.3	1.1
Hypothyroidism (self reported)	1.1	2.6	3.9	1.7	1.4	2.0	1.6	1.6	1.7	1.7	1.1	1.8	1.6	1.4
Relative age voice broke	1.1	1.7	2.8	-1.3	-1.7	-1.3	-1.6	-0.7	-1.4	-1.3	-0.8	-1.4	-0.7	-1.6
Medication: Levothyroxine sodium	1.1	1.8	2.4	1.4	1.4	1.5	1.1	1.4	1.4	1.2	1.4	1.4	1.0	1.5
Headache pain in last month	1.1	1.8	3.4	-1.4	-1.2	-1.5	-1.0	-1.3	-1.3	-1.8	-1.8	-1.4	-0.5	-1.0
Comparative body size at age 10	1.1	3.0	4.8	-1.7	-1.7	-2.2	-1.7	-1.3	-1.8	-1.6	-1.5	-1.7	-1.8	-1.7
Migraine (self-reported)	1.1	1.4	2.0	-1.0	-1.1	-1.4	-1.3	-0.8	-1.0	-1.3	-1.4	-1.0	-1.1	-1.2
Medication: Ibuprofen	1.1	1.3	1.9	1.0	1.3	1.1	1.1	1.0	1.1	0.5	1.4	1.0	1.2	1.4
Medication: Aspirin	1.1	1.5	2.4	-1.1	-1.6	-1.3	-1.3	-0.9	-1.2	-1.0	-1.2	-1.1	-1.1	-1.4
Tinnitus: Yes, now most or all of the time	1.1	1.2	3.0	0.9	1.5	1.3	1.0	0.5	1.0	0.3	1.7	0.9	1.0	1.4
High cholesterol (Self-reported)	1.1	2.0	3.1	1.4	1.3	1.2	1.2	1.8	1.4	1.1	1.6	1.4	1.7	1.2
Intelligence (Savage-Jansen 2018)	1.0	3.1	4.9	-1.8	-2.1	-1.9	-2.1	-1.1	-1.9	-1.4	-1.4	-1.9	-1.1	-2.2
Medication: Metformin	1.0	1.4	2.6	1.1	1.5	0.8	1.2	0.6	1.2	1.5	1.3	1.2	-0.0	1.6
Impedance of leg (left)	1.0	4.9	6.5	2.4	2.1	2.2	2.1	2.2	2.5	2.2	1.7	2.4	1.6	2.6
Allergy	1.0	2.2	3.5	1.9	1.3	1.5	1.6	1.5	1.8	1.4	0.5	1.9	1.0	1.3
Father’s age at death	1.0	1.3	2.9	0.8	1.1	1.5	1.3	1.5	0.8	1.7	0.7	0.8	1.1	1.0
Falls in the last year	1.0	1.3	3.3	1.1	1.0	1.1	1.8	1.0	1.1	0.9	1.0	1.1	1.1	1.1
Gout (self-reported)	1.0	1.3	2.1	-1.2	-1.1	-1.4	-1.3	-0.9	-1.3	-1.2	-1.0	-1.2	-0.4	-1.2
Illnesses of father: Heart disease	1.0	1.4	2.2	1.5	1.1	0.8	1.4	1.4	1.4	0.9	0.8	1.4	0.7	1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	1.9	1.1	0.9	1.1	1.0	1.4	1.1	1.0	0.6	1.0	0.4	1.1
Osteoporosis (self-reported)	1.0	1.2	2.1	-1.4	-0.9	-1.3	-1.0	-1.2	-1.4	-1.0	-0.9	-1.4	-0.6	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	3.0	-1.6	-1.7	-1.4	-1.5	-1.3	-1.7	-0.9	-1.2	-1.6	-1.2	-1.7
Medication: Paracetamol	1.0	1.6	2.9	1.2	1.6	0.9	1.7	1.0	1.2	1.2	0.3	1.2	1.3	1.5
Myopia	1.0	1.4	2.5	-1.4	-0.8	-1.0	-1.2	-1.6	-1.3	-1.3	-0.1	-1.4	-1.3	-0.9
Cholesterol lowering medication	1.0	1.5	2.4	1.2	1.1	1.1	1.3	1.6	1.2	1.4	0.7	1.2	1.4	1.1
Lupus	0.9	1.3	2.2	-1.3	-1.5	-1.1	-0.8	-0.8	-1.3	-1.0	-1.0	-1.3	-0.9	-1.3
Triglycerides	0.9	1.5	2.8	-1.2	-1.3	-1.1	-1.1	-1.7	-1.1	-1.6	-1.1	-1.2	-1.3	-1.0
Relative age of first facial hair	0.9	1.9	2.9	-1.7	-1.7	-1.1	-1.6	-0.9	-1.7	-0.8	-1.1	-1.7	-0.7	-1.7
Impedance of arm (left)	0.9	4.3	5.7	2.1	2.1	2.2	1.8	1.9	2.1	2.1	1.8	2.1	2.1	2.4
Birth weight of first child	0.9	1.7	2.3	1.5	1.5	1.0	1.5	1.1	1.5	1.1	1.0	1.5	0.5	1.5
Emphysema/chronic bronchitis	0.9	1.0	1.6	-1.2	-1.1	-0.7	-0.6	-0.8	-1.2	-0.8	-1.0	-1.2	-1.0	-1.0
Friendships satisfaction	0.9	1.1	2.1	-1.2	-1.1	-1.0	-0.5	-1.1	-1.2	-0.7	-1.4	-1.2	-0.8	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.1	-0.8	-1.0	-1.4	-1.4	-1.0	-0.9	-1.1	-1.3	-0.8	-0.8	-0.9
Schizophrenia vs Biploar Disorder	0.8	1.1	2.5	1.0	1.0	1.1	0.9	1.3	0.9	0.9	1.6	0.9	-0.2	1.0
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.4	0.9	1.1	0.7	1.4	0.8	1.0	1.5	-0.4	1.0	0.9	1.1
Ever had hysterectomy (womb removed)	0.8	0.9	2.8	-0.7	-0.4	-1.2	-0.6	-1.1	-0.6	-1.7	-1.4	-0.7	-0.9	-0.3
Qualifications: CSEs or equivalent	0.8	1.1	2.1	-1.0	-1.1	-1.0	-1.0	-0.6	-0.9	-1.4	-1.4	-1.0	-1.1	-0.8
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.3	-1.8	-1.0	-1.3	-1.3	-1.5	-1.7	-1.5	0.0	-1.8	-0.8	-1.1
Supplements: Glucosamine	0.8	1.0	2.1	0.7	1.0	1.3	1.0	0.8	0.7	1.3	1.4	0.7	0.8	0.9
Number of live births	0.8	1.1	1.8	1.3	1.2	0.9	1.0	0.6	1.3	0.0	1.2	1.2	0.2	1.2
Pulse wave reflection index	0.8	1.0	2.8	-0.7	-0.9	-0.7	-1.2	-0.9	-0.8	-1.2	0.9	-0.8	-1.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.5	-1.0	-1.2	-1.1	-0.7	-0.8	-1.0	-1.2	-0.8	-1.0	-0.9	-1.1
Number of full brothers	0.8	1.0	1.6	-0.9	-1.1	-1.3	-1.0	-1.1	-0.9	-0.9	-1.3	-0.9	-0.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.5	-1.0	-1.0	-0.6	-1.2	-1.1	-1.0	-0.8	-1.0	-1.0	-0.6	-1.1
Average weekly champagne plus white wine intake	0.8	1.1	1.4	1.1	1.1	1.1	0.9	1.2	1.2	1.1	0.7	1.2	0.7	1.0
Alcohol drinker status: Never	0.8	1.0	1.7	1.0	1.3	0.9	0.8	1.1	1.0	0.7	1.1	0.9	0.5	1.3
Smoking Status	0.7	1.7	2.4	1.4	1.3	1.4	1.3	1.0	1.4	1.5	1.1	1.4	0.6	1.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	-0.8	-1.2	-1.1	-0.5	-0.6	-0.9	-0.6	-0.8	-0.8	-1.1	-0.9
Nervous feelings	0.7	1.3	2.2	-1.2	-1.2	-0.9	-1.1	-0.6	-1.2	-1.2	-1.5	-1.2	-0.7	-1.2
Impedance of arm (right)	0.7	3.4	4.5	1.9	1.7	2.1	1.8	1.7	1.9	2.0	1.5	1.9	1.8	2.0
Time employed in main current job	0.7	0.8	2.1	0.9	1.5	0.6	1.0	0.6	1.0	0.4	0.8	0.9	0.7	1.2
Illnesses of mother	0.7	0.9	2.5	1.0	0.9	0.9	1.6	0.1	1.1	0.5	0.0	1.1	0.8	1.2
Blood clot in the leg (DVT)	0.7	0.9	1.5	-0.8	-0.9	-1.2	-1.2	-0.9	-0.8	-1.0	-1.2	-0.8	-0.5	-0.8
Knee pain experienced in last month	0.7	1.1	1.8	1.4	1.2	1.2	1.0	0.9	1.3	0.5	0.6	1.3	0.2	1.3
Osteoarthritis (self-reported)	0.7	1.0	1.5	0.8	1.2	1.1	1.2	0.8	0.9	0.8	1.2	0.8	0.6	1.1
Illnesses of father: High blood pressure	0.7	0.8	1.8	-0.7	-1.4	-0.5	-1.2	0.3	-0.8	-1.1	-1.0	-0.8	0.4	-1.2
Ever smoked	0.7	1.2	2.0	1.2	1.0	1.1	1.0	0.5	1.2	1.4	1.4	1.2	0.8	1.0
Schizophrenia (2014)	0.6	1.2	1.8	1.2	1.3	0.9	1.0	1.1	1.2	1.0	1.3	1.2	0.4	1.2
Cardiovascular Disease	0.6	2.0	3.8	1.1	1.0	1.6	1.8	1.8	1.2	1.1	1.2	1.0	2.0	1.2
Sitting height	0.6	4.1	6.4	2.2	2.5	1.9	2.1	1.3	2.2	2.1	2.1	2.2	0.2	2.5
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.1	1.0	0.6	1.4	1.1	1.4	0.9	1.0	0.6	0.9	0.9	0.6
Birth weight	0.6	1.2	2.4	-1.3	-0.9	-1.5	-0.7	-0.8	-1.3	-1.6	-0.4	-1.4	-0.7	-1.0
Worry too long after embarrassment	0.6	1.1	1.9	-1.3	-1.1	-0.4	-1.4	-0.4	-1.2	-0.7	-1.2	-1.2	0.2	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.0	0.6	0.6	0.9	0.5	1.3	0.6	1.4	0.8	0.6	0.8	0.6
Major Depression (MDD)	0.5	0.7	1.3	0.7	1.0	0.8	1.1	0.8	0.8	0.7	0.7	0.8	0.0	1.0
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.8	0.7	1.2	0.7	1.3	1.2	0.8	1.2	0.5	0.8	0.4	1.2
Diabetes (father)	0.5	0.6	1.8	0.4	0.5	1.1	0.5	1.2	0.4	0.8	1.4	0.3	0.8	0.5
Alcohol usually taken with meals	0.5	0.8	1.7	0.8	0.8	1.2	0.6	1.3	0.8	0.5	1.0	0.8	1.1	0.9
Pulse wave Arterial Stiffness index	0.5	0.5	2.6	0.7	0.7	0.5	0.2	0.5	0.7	-0.7	1.6	0.6	-0.1	0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	-0.4	-1.1	-0.8	-0.5	-1.1	-0.4	-0.9	-0.9	-0.4	-0.9	-0.7
Chest pain or discomfort	0.5	0.8	1.1	-0.7	-1.1	-1.0	-1.0	-1.1	-0.7	-0.9	-1.1	-0.7	-0.5	-0.9
Had major operations	0.5	0.6	1.2	1.0	0.8	0.4	1.1	0.1	1.0	0.6	0.4	1.0	-0.4	0.8
Long-standing illness, disability or infirmity	0.5	0.7	1.6	0.8	1.1	0.4	1.0	0.8	0.9	0.9	0.2	0.9	0.4	1.2
Smoking status: Current	0.5	0.8	1.6	-0.8	-0.6	-1.0	-1.0	-1.0	-0.8	-0.5	-1.2	-0.8	-1.0	-0.8
Miserableness	0.5	0.8	1.7	0.7	1.3	1.0	1.0	0.4	0.9	-0.1	0.7	0.7	1.3	1.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.2	0.8	1.1	0.6	0.6	-0.1	0.8	0.5	1.1	0.8	-0.1	1.0
Diastolic blood pressure, automated reading	0.5	1.4	3.3	1.2	0.7	1.2	1.5	1.8	1.2	0.1	-0.7	1.0	1.7	0.8
Unable to work because of sickness or disability	0.5	0.6	2.4	-0.5	-0.2	-0.8	-0.4	-1.1	-0.5	-1.5	-0.8	-0.6	-0.9	-0.2
Irritable Bowel Disease (IBD)	0.4	0.9	1.9	0.8	1.0	0.8	0.9	1.4	0.7	1.1	1.3	0.8	0.3	1.0
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.9	-1.0	-1.3	-0.9	-1.3	-0.6	-1.1	-0.7	-0.6	-1.1	-0.3	-1.4
Breast Cancer	0.4	1.0	1.8	-1.1	-1.1	-0.6	-1.0	-1.4	-1.1	-0.8	0.3	-1.1	-1.3	-0.9
Mean Putamen Volume	0.4	0.4	1.4	0.5	0.2	0.8	0.6	0.7	0.6	0.8	-0.1	0.6	1.2	0.2
HbA1C	0.4	0.4	1.2	-1.0	-0.2	-0.5	-0.3	0.2	-0.8	-0.2	-1.1	-1.0	0.1	-0.1
Ulcerative Colitis	0.4	0.6	1.5	0.8	0.6	0.5	0.9	1.2	0.7	0.9	0.7	0.8	0.4	0.7
Lung FEV1/FVC ratio	0.4	2.0	3.1	-1.1	-1.4	-1.4	-1.4	-1.2	-1.2	-1.5	-1.7	-1.2	-1.8	-1.5
Hand grip strength (left)	0.4	1.0	1.8	1.1	0.8	1.3	1.1	1.3	1.1	1.2	0.4	1.1	0.8	0.6
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.3	-0.3	0.3	-0.6	-0.2	-1.0	-0.2	-1.0	0.0	-0.3	-1.5	0.4
Current tobacco smoking	0.4	0.7	1.6	-0.6	-0.6	-1.0	-0.9	-0.8	-0.6	-0.6	-1.3	-0.6	-1.0	-0.7
Hair/balding pattern: Pattern 2	0.4	0.5	1.1	0.9	0.6	0.5	0.2	0.5	0.8	0.6	0.8	0.9	1.1	0.7
Had menopause	0.4	0.5	1.8	0.5	0.4	0.7	0.7	0.7	0.5	1.0	0.4	0.6	1.3	0.5
Noisy workplace	0.4	0.5	2.4	-0.5	-0.4	-0.5	-0.1	-1.6	-0.5	-0.6	0.0	-0.5	-1.1	-0.4
Length of working week for main job	0.4	0.4	1.9	0.5	0.4	0.6	0.8	0.4	0.5	1.4	0.6	0.5	-0.4	0.3
Medication: Paracetamol	0.4	0.6	1.8	0.8	0.9	0.3	1.3	0.5	0.8	0.4	-0.6	0.8	0.8	0.9
Glaucoma (self-reported)	0.4	0.5	1.6	0.7	0.9	0.4	-0.1	0.8	0.7	-0.1	1.3	0.6	0.5	0.8
Health satisfaction	0.4	0.5	1.6	0.6	0.9	0.6	1.2	0.5	0.7	0.6	0.1	0.6	0.4	0.9
Medication: Allopurinol	0.4	0.6	1.2	-0.8	-0.5	-0.8	-1.1	-1.1	-0.8	-0.9	0.1	-0.8	-0.4	-0.6
Number of full sisters	0.4	0.4	1.5	-0.4	-0.1	-1.1	-0.3	-0.1	-0.4	-1.2	-0.8	-0.5	-0.9	-0.1
Ever had bowel cancer screening	0.4	0.5	1.2	0.9	0.7	0.1	0.5	1.1	0.8	0.2	0.1	0.8	0.6	0.8
Medication for cholesterol	0.4	0.6	1.8	-0.5	-0.3	-0.7	-0.8	-1.3	-0.4	-0.9	-0.6	-0.4	-1.2	-0.4
Guilty feelings	0.4	0.5	1.4	0.7	1.2	0.6	0.9	0.2	0.8	0.3	0.3	0.7	-0.1	1.2
Schizophrenia (2018)	0.3	0.7	1.0	0.9	0.9	0.6	0.8	1.0	0.9	1.0	0.8	0.9	0.6	0.8
LDL Cholesterol	0.3	0.5	1.3	-0.5	-0.6	-0.4	-0.3	-1.2	-0.5	-0.8	0.3	-0.6	-1.1	-0.4
BMI	0.3	1.7	4.4	-1.0	-1.3	-1.6	-1.0	-1.0	-1.1	-2.1	-1.0	-1.1	-1.2	-1.5
Waist Hip Ratio (WHR)	0.3	1.4	2.8	1.1	1.7	0.9	1.2	0.9	1.2	1.2	1.0	1.2	0.7	1.6
Allergy or Eczema	0.3	0.9	2.1	-1.3	-0.4	-0.7	-0.5	-1.4	-1.2	-0.9	0.6	-1.3	-0.4	-0.6
Lung FVC	0.3	1.6	2.2	-1.2	-1.5	-1.3	-1.2	-1.2	-1.3	-0.6	-1.3	-1.1	-1.5	-1.5
Chronotype (morning person)	0.3	0.6	1.4	0.9	0.7	0.3	0.3	1.2	0.8	0.8	1.2	0.8	0.3	0.8
Hearing difficulty/problems: Yes	0.3	0.5	1.2	0.7	0.6	0.5	0.8	0.2	0.6	0.9	1.1	0.7	0.3	0.7
Hand grip strength (right)	0.3	0.8	1.3	1.1	0.9	0.9	1.1	0.6	1.1	0.9	0.6	1.1	0.6	0.7
Taking other prescription medications	0.3	0.5	0.9	0.5	0.9	0.5	0.4	0.8	0.7	0.8	0.2	0.6	0.7	0.9
Body mass index (BMI)	0.3	1.4	3.2	-0.9	-1.4	-1.3	-0.8	-0.9	-1.0	-1.8	-1.0	-1.0	-1.0	-1.5
Pain all over the body in last month	0.3	0.3	0.6	0.6	0.7	0.1	0.7	0.3	0.6	0.3	0.1	0.6	-0.6	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	0.6	1.1	0.4	0.6	0.5	0.8	0.1	0.5	0.6	0.0	1.2
Hair/balding pattern: Pattern 3	0.3	0.4	1.1	-0.7	-0.3	-0.1	-1.0	-0.2	-0.8	-0.5	0.9	-0.8	0.1	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.6	2.4	-0.3	-0.1	-0.9	-0.5	-1.4	-0.3	-0.6	0.0	-0.3	-1.5	0.1
Depression (self-reported)	0.3	0.3	1.1	-0.5	-0.4	-0.7	-0.4	-0.5	-0.4	-1.0	-0.1	-0.5	-1.0	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	2.4	-0.2	0.5	0.4	0.1	0.2	-0.1	0.6	1.6	-0.1	0.1	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.9	0.9	0.5	0.4	0.4	0.9	0.8	0.7	-0.1	0.9	0.1	0.5
Number of children fathered	0.3	0.3	0.9	0.5	0.7	0.2	0.1	0.3	0.4	0.4	1.0	0.5	0.9	0.6
Pulse wave peak to peak time	0.3	0.4	2.0	-0.4	-0.5	-0.2	0.0	-0.3	-0.4	0.9	-1.4	-0.3	0.3	-0.6
Medication: Blood pressure	0.3	0.5	0.7	0.7	0.3	0.8	0.5	0.8	0.6	0.6	0.8	0.7	0.8	0.5
Suffer from ‘nerves’	0.3	0.5	1.3	-0.8	-0.7	-0.7	-0.9	-0.1	-0.8	-0.6	-1.1	-0.8	-0.1	-0.7
Age at last live birth	0.3	0.4	1.1	0.4	0.5	1.0	0.9	0.6	0.4	1.0	-0.5	0.5	0.4	0.3
Leg fat-free mass (right)	0.3	1.4	2.0	-1.3	-1.1	-1.0	-0.8	-1.3	-1.3	-1.4	-0.8	-1.4	-1.3	-1.4
Average weekly red wine intake	0.3	0.5	1.0	-0.6	-0.8	-1.0	-0.6	-0.5	-0.7	-0.8	-0.9	-0.7	-0.3	-0.7
Loneliness, isolation	0.3	0.4	0.7	0.8	0.7	0.4	0.7	0.3	0.8	0.1	-0.2	0.8	0.0	0.8
Back pain experienced in last month	0.3	0.5	1.1	0.6	0.7	0.7	0.9	0.4	0.7	0.1	0.3	0.6	0.9	1.0
Leg predicted mass (right)	0.3	1.5	2.0	-1.3	-1.1	-1.0	-0.9	-1.3	-1.3	-1.4	-0.8	-1.4	-1.3	-1.4
Financial situation satisfaction	0.3	0.4	1.2	0.4	0.9	0.9	1.1	0.4	0.4	0.6	0.5	0.3	-0.2	0.7
Age started oral contraceptive pill	0.3	0.4	2.1	0.3	-0.1	0.4	0.0	1.0	0.2	0.7	-0.1	0.3	1.4	-0.3
Ever depressed for a whole week	0.3	0.4	1.0	0.7	0.7	0.4	1.0	0.5	0.7	0.7	-0.1	0.7	-0.0	0.6
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	0.4	0.7	0.3	0.1	0.3	0.4	0.5	0.9	0.4	0.9	0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.4	0.5	0.1	0.5	0.2	0.6	0.4	0.7	0.7	0.5	1.5	0.2
Heart disease (siblings)	0.3	0.4	1.2	-0.2	-0.3	-1.1	-0.7	-0.8	-0.2	-0.8	-0.3	-0.2	-1.1	-0.3
Depressed Affect (Nagel 2018)	0.2	0.5	1.5	0.6	1.1	0.4	0.9	-0.1	0.8	-0.2	0.6	0.6	0.4	1.2
Ulcerative Colitis (UC)	0.2	0.5	1.3	0.5	0.7	0.4	0.7	1.0	0.4	0.6	1.1	0.4	0.2	0.7
Reaction Time	0.2	0.4	0.9	-0.8	-0.7	-0.4	-0.6	-0.7	-0.8	-0.4	-0.9	-0.7	-0.4	-0.6
Coronary Artery Disease (CAD)	0.2	0.2	0.4	-0.4	-0.6	-0.5	-0.4	-0.5	-0.5	-0.5	-0.3	-0.5	-0.3	-0.6
Neuroticism (2016)	0.2	0.3	1.3	-0.3	0.4	0.1	-0.5	0.1	-0.2	-1.1	0.7	-0.4	0.5	0.4
Systolic Blood Pressure	0.2	1.2	3.0	1.0	0.8	1.3	1.7	1.7	1.1	0.5	0.3	0.9	0.9	0.9
Sensitivity / hurt feelings	0.2	0.3	0.9	-0.5	-0.3	-0.6	-0.7	-0.4	-0.5	-0.9	0.1	-0.6	-0.5	-0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.6	0.5	0.4	0.8	0.5	0.6	0.5	0.5	0.3	0.5	0.4	0.5
Systolic blood pressure, automated reading	0.2	0.5	1.6	0.6	0.0	0.7	1.2	1.2	0.6	0.3	-0.6	0.5	0.6	0.0
Medication for hormone replacement therapy	0.2	0.2	0.5	0.4	0.2	0.6	0.5	0.7	0.4	0.5	0.2	0.4	0.2	0.4
Supplements: Zinc	0.2	0.3	1.5	0.3	0.4	0.5	0.4	0.5	0.3	0.2	-0.1	0.3	1.2	0.5
Severe depression (siblings)	0.2	0.2	0.5	0.7	0.5	0.1	0.1	0.3	0.7	0.4	0.7	0.7	0.4	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.6	0.1	0.7	-0.2	0.2	-0.5	0.2	-0.6	-0.1	0.1	-0.7	0.8
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.0	0.0	0.5	0.0	0.4	-0.1	0.1	-0.1	1.0	-0.0	-0.3	0.7
High blood pressure	0.2	0.6	2.3	0.4	0.0	0.8	0.7	1.3	0.4	0.8	0.3	0.3	1.5	0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	-0.2	-0.0	-0.4	0.4	-0.2	-0.3	-0.6	-1.0	-0.2	0.2	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.3	0.7	-0.6	-0.1	-0.7	-0.3	-0.3	-0.5	-0.7	-0.8	-0.6	-0.3	-0.2
Waist circumference	0.2	0.8	1.7	-0.8	-0.9	-1.0	-0.7	-0.7	-0.8	-1.3	-0.7	-0.8	-0.8	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.2	-0.3	0.5	-0.4	0.5	-0.6	-0.2	-1.1	-0.1	-0.4	-0.0	0.6
Qualifications: None of the above	0.2	0.4	0.8	0.7	0.9	0.4	0.1	0.0	0.7	0.3	0.9	0.7	0.9	0.8
Financial difficulties in last 2 years	0.2	0.3	0.7	0.6	0.4	0.4	0.7	0.8	0.6	0.2	-0.2	0.6	-0.1	0.4
Mouth/teeth dental problems	0.2	0.3	1.2	0.0	-0.1	0.6	0.5	0.9	0.0	0.1	0.4	-0.0	1.1	-0.3
Heart attack	0.2	0.3	2.0	0.3	-0.1	0.4	0.0	0.5	0.2	0.6	0.6	0.3	1.4	0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.5	-0.7	-0.9	-0.7	-0.7	-0.9	-0.7	-0.3	-0.4	-0.6	-1.2	-0.8
Medication: Lansoprazole	0.2	0.2	0.5	-0.2	-0.2	-0.6	-0.5	0.4	-0.3	-0.7	-0.4	-0.3	-0.6	-0.3
Lung cancer (father)	0.2	0.3	0.6	0.6	0.5	0.3	0.3	-0.1	0.6	0.8	0.2	0.7	-0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	1.7	-0.9	-1.0	-0.7	-0.7	-1.1	-0.9	-0.2	-0.2	-0.9	-1.3	-0.9
Standing height	0.2	2.4	3.6	1.4	1.9	1.7	1.6	0.9	1.5	1.7	1.9	1.4	0.4	1.8
Breastfed as a baby	0.2	0.2	0.4	0.3	0.5	0.2	0.4	0.7	0.3	0.4	0.6	0.3	0.6	0.4
Tense / ‘highly strung’	0.2	0.3	1.2	-0.5	-0.2	-0.4	-0.6	-1.1	-0.4	-0.1	-0.8	-0.4	-0.6	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.7	-0.6	-0.8	0.2	-0.3	-0.4	-0.5	0.4	-0.0	-0.5	0.1	-0.7
Leg pain on walking	0.2	0.3	2.2	0.1	-0.1	-0.1	0.1	0.5	0.1	0.5	-1.5	0.2	0.7	-0.0
Hypertension (Self-reported)	0.2	0.7	2.0	0.5	0.1	1.0	0.9	1.4	0.5	0.8	0.4	0.4	1.4	0.2
Commuting to job workplace: Walk	0.2	0.3	1.3	-0.1	-0.5	-0.6	-0.2	-0.7	-0.1	-0.4	-0.4	-0.1	-1.1	-0.4
Eye problems/disorders: Cataract	0.2	0.2	0.7	0.1	0.8	-0.2	0.2	-0.3	0.1	-0.4	0.5	0.0	-0.7	0.8
Hearing aid user	0.2	0.2	0.5	0.7	0.3	0.1	0.6	0.2	0.6	0.5	0.1	0.7	-0.2	0.5
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	0.5	0.5	-0.1	-0.6	0.2	0.4	-0.6	0.4	0.4	0.1	0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.7	-0.5	-0.4	-0.3	-0.5	-0.7	-0.5	-0.3	-0.8	-0.5	-0.6	-0.2
Medication: Lisinopril	0.2	0.2	0.9	-0.2	-0.0	0.5	0.4	1.0	-0.2	0.8	0.2	-0.2	0.7	-0.0
Irritability	0.2	0.3	1.7	-0.7	0.0	-0.1	-0.4	-1.3	-0.5	-0.0	0.0	-0.6	-0.5	-0.0
Fractured/broken bones in last 5 years	0.2	0.2	0.8	-0.3	-0.9	-0.4	-0.5	-0.3	-0.3	-0.4	-0.4	-0.3	-0.1	-0.7
Bipolar Disorder or Schizophrenia	0.1	0.4	0.9	-0.5	-0.6	-0.7	-0.5	-0.4	-0.5	-0.4	-0.9	-0.5	-0.3	-0.9
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	0.5	0.5	0.4	0.4	0.4	0.5	0.4	0.4	0.4	0.2	0.4
Prostate Cancer	0.1	0.2	0.7	0.0	-0.1	0.4	-0.3	0.5	-0.0	0.1	0.8	-0.0	0.8	-0.1
Bipolar Disorder (2011)	0.1	0.1	0.4	-0.5	-0.4	-0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.1	0.1	0.2	-0.1	-0.1	-0.3	0.4	0.2	-0.1	0.5	-0.5	-0.1	-0.1	-0.0
Blood Eosinophil Count	0.1	0.7	1.6	-0.5	-0.5	-1.2	-1.0	-0.6	-0.5	-0.9	-0.8	-0.5	-1.1	-0.5
Blood Red Count	0.1	1.0	2.3	1.1	1.0	1.0	1.5	1.3	1.1	1.0	0.3	1.1	0.0	0.8
Blood White Count	0.1	0.5	1.3	0.7	0.7	0.6	0.2	1.1	0.7	0.8	0.7	0.7	0.5	0.6
Neuroticism	0.1	0.1	0.5	0.1	0.6	0.6	0.0	0.3	0.3	0.2	0.3	0.2	0.4	0.7
Tanning	0.1	1.3	2.9	-1.1	-1.0	-1.2	-1.0	-1.4	-1.1	-0.8	-0.7	-1.0	-1.7	-1.1
Diabetes (mother)	0.1	0.2	0.5	-0.1	-0.5	-0.3	-0.6	0.1	-0.2	-0.0	-0.4	-0.1	-0.7	-0.7
Leg fat-free mass (left)	0.1	0.7	1.1	-0.8	-0.7	-0.7	-0.5	-0.9	-0.9	-1.0	-0.6	-0.9	-1.0	-1.0
Trunk fat percentage	0.1	0.3	0.8	0.9	0.3	0.5	0.6	0.5	0.8	-0.1	0.7	0.8	0.2	0.4
Maternal smoking around birth	0.1	0.1	0.4	0.2	-0.1	-0.3	0.2	-0.4	0.2	-0.6	-0.1	0.2	-0.1	0.1
Fed-up feelings	0.1	0.2	0.9	-0.2	-0.0	-0.3	-0.7	-0.5	-0.2	-1.0	-0.3	-0.3	-0.7	0.1
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.3	0.1	-0.1	0.3	0.3	-0.2	-0.6	-0.2	-0.3	0.5	0.2
Medication: Atenolol	0.1	0.2	0.5	0.3	0.2	0.3	0.2	0.6	0.3	0.6	0.7	0.3	0.6	0.1
Leg predicted mass (left)	0.1	0.8	1.1	-0.9	-0.8	-0.8	-0.5	-0.9	-0.9	-1.0	-0.6	-1.0	-1.0	-1.1
Number of incorrect matches in round	0.1	0.2	0.9	0.1	-0.2	0.2	0.1	0.3	0.1	-0.0	-0.8	0.1	0.9	-0.2
Fluid intelligence score	0.1	0.3	0.5	-0.6	-0.6	-0.2	-0.7	-0.5	-0.6	-0.4	-0.1	-0.6	-0.0	-0.7
Illnesses of siblings	0.1	0.1	0.2	-0.5	-0.2	-0.1	-0.3	0.1	-0.5	0.4	0.0	-0.4	-0.4	-0.2
Neuroticism score	0.1	0.2	0.5	-0.4	0.1	-0.3	-0.5	-0.4	-0.3	-0.4	-0.7	-0.4	-0.3	-0.0
Weight	0.1	0.3	1.0	-0.2	-0.5	-0.6	-0.2	-0.5	-0.3	-1.0	-0.1	-0.4	-0.8	-0.6
Trunk fat-free mass	0.1	0.7	1.6	-0.9	-0.7	-0.8	-0.6	-1.0	-0.9	-0.9	-0.3	-0.9	-1.3	-0.9
Hip circumference	0.1	0.5	1.1	-0.5	-0.9	-0.6	-0.3	-0.7	-0.6	-0.9	-0.5	-0.6	-0.8	-1.0
Happiness	0.1	0.2	0.4	-0.4	0.3	-0.3	0.5	-0.6	-0.2	-0.3	-0.6	-0.3	-0.6	0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.6	-0.3	-0.7	0.1	-0.3	0.3	-0.4	0.3	-0.1	-0.3	-0.0	-0.8
Medication: Cholesterol lowering	0.1	0.1	0.6	0.2	-0.0	-0.1	0.1	-0.1	0.2	-0.2	0.8	0.2	0.3	0.0
Trunk predicted mass	0.1	0.6	1.4	-0.8	-0.6	-0.7	-0.6	-0.9	-0.8	-0.9	-0.1	-0.9	-1.2	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.3	-0.1	0.2	-0.1	0.2	-0.1	-0.1	-0.2	-0.5	-0.1	-1.1	0.1
Hair/balding pattern: Pattern 4	0.1	0.2	1.0	0.0	0.2	-0.1	1.0	-0.0	0.1	0.0	-1.0	0.1	-0.2	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.5	0.2	0.7	0.2	0.7	-0.1	0.3	0.5	0.2	0.2	0.2	0.6
Loud music exposure frequency	0.1	0.2	0.4	-0.6	-0.4	0.1	-0.2	-0.6	-0.6	0.2	-0.1	-0.6	-0.0	-0.3
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.4	-0.5	-0.0	-0.2	-0.1	-0.2	-0.4	-0.0	-0.6	-0.4	-0.3	-0.1
High blood pressure (siblings)	0.1	0.2	0.4	0.5	-0.1	0.5	0.6	0.3	0.5	0.0	-0.3	0.5	0.6	0.1
Forced vital capacity (FVC), Best measure	0.1	0.3	1.2	-0.5	-0.6	-0.3	-0.1	-0.8	-0.5	0.7	0.4	-0.4	-1.1	-0.5
Body fat percentage	0.1	0.2	0.6	0.8	0.2	0.2	0.5	0.4	0.7	-0.3	0.4	0.7	0.1	0.2
Leg fat percentage (right)	0.1	0.3	0.8	0.9	0.2	0.2	0.7	0.9	0.8	-0.0	0.3	0.8	0.4	0.2
Arm fat-free mass (right)	0.1	0.3	1.1	-0.4	-0.1	-0.5	-0.2	-0.6	-0.4	-0.7	-0.0	-0.4	-1.0	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.1	0.6	-0.0	-0.0	0.1	-0.2	-0.4	-0.1	0.3	0.6	-0.0	-0.8	-0.2
Neck or shoulder pain in last month	0.1	0.2	0.4	-0.4	-0.4	-0.6	-0.1	-0.4	-0.4	-0.5	-0.2	-0.4	-0.6	-0.2
Medication: Omeprazole	0.1	0.1	0.3	-0.3	-0.2	-0.2	0.2	0.6	-0.3	0.3	-0.1	-0.3	0.3	-0.2
Mean time to correctly identify matches	0.1	0.2	0.7	-0.3	-0.4	0.3	-0.2	-0.0	-0.3	0.2	-0.8	-0.2	0.6	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.7	-0.3	-0.1	-0.0	-0.3	0.1	-0.3	-0.1	0.8	-0.3	0.1	-0.1
Arm predicted mass (right)	0.1	0.4	1.2	-0.4	-0.3	-0.6	-0.3	-0.8	-0.5	-0.8	-0.1	-0.5	-1.1	-0.6
Comparative height size at age 10	0.1	0.4	0.9	-0.5	-0.5	-0.6	-0.3	-0.9	-0.6	-0.6	-0.0	-0.6	-0.9	-0.6
Overall health rating	0.1	0.2	0.5	-0.0	0.3	-0.2	0.4	-0.2	0.1	-0.5	-0.7	-0.0	-0.7	0.5
Whole body fat-free mass	0.1	0.6	1.3	-0.8	-0.7	-0.7	-0.5	-0.8	-0.8	-0.9	-0.3	-0.9	-1.2	-0.9
Mood swings	0.1	0.2	0.8	-0.4	0.1	-0.5	-0.1	-0.8	-0.2	-0.9	-0.4	-0.3	-0.8	0.2
Qualifications: nursing, teaching	0.1	0.2	0.7	0.0	0.1	0.6	0.2	0.6	0.0	0.9	0.6	0.1	0.6	0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	-0.1	0.2	0.1	0.2	-0.6	-0.1	0.4	0.2	-0.0	-0.7	0.2
Whole body water mass	0.1	0.7	1.5	-0.8	-0.7	-0.7	-0.5	-0.9	-0.9	-0.9	-0.3	-0.9	-1.2	-0.9
Number of self-reported non-cancer illnesses	0.1	0.1	0.8	-0.3	-0.3	-0.5	0.1	0.2	-0.3	-0.2	-0.9	-0.3	-0.2	-0.3
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	0.0	-0.3	-0.1	-0.2	-0.1	-0.5	-0.1	-0.1	-0.5	0.0
Mother’s age at death	0.1	0.1	0.4	0.0	0.5	0.2	0.2	0.5	0.1	0.5	0.5	0.1	0.6	0.4
Commuting to job workplace: Public transport	0.1	0.1	0.2	0.2	0.1	-0.2	-0.4	-0.0	0.1	0.4	0.4	0.2	-0.3	-0.2
Medication: Blood pressure	0.1	0.2	1.0	-0.1	0.0	0.3	0.4	0.9	-0.0	0.4	0.2	-0.1	1.0	0.0
Medication: Atorvastatin	0.1	0.1	0.3	-0.1	-0.1	-0.5	0.1	-0.5	-0.1	-0.4	-0.4	-0.0	0.5	-0.1
Basal metabolic rate	0.1	0.5	1.3	-0.6	-0.5	-0.7	-0.4	-0.8	-0.6	-1.0	-0.2	-0.7	-1.1	-0.8
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.4	-0.0	0.5	-0.4	-0.3	-0.9	0.1	-0.6	0.0	0.0	-1.2	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.5	0.1	0.1	0.0	0.7	0.6	0.1	0.3	-0.4	0.1	-0.0	0.1
Pain experienced in last month	0.1	0.2	0.9	-0.4	-0.6	0.1	-0.5	-0.1	-0.5	0.1	0.2	-0.4	-0.2	-0.9
Supplements: Calcium	0.1	0.1	0.6	-0.3	-0.2	-0.3	-0.3	-0.4	-0.3	-0.8	0.1	-0.3	-0.3	-0.2
Alcohol drinker status: Previous	0.1	0.1	1.0	0.1	-0.1	-0.7	-0.1	0.1	0.1	0.2	-1.0	0.2	0.0	-0.1
Arm predicted mass (left)	0.1	0.3	1.1	-0.3	-0.4	-0.5	-0.2	-0.6	-0.4	-0.7	0.0	-0.4	-1.1	-0.6
Neuroticism (Nagel 2018)	0.0	0.1	0.3	0.3	0.4	0.0	0.0	-0.5	0.3	-0.2	0.4	0.3	-0.2	0.4
Worry (Nagel 2018)	0.0	0.1	0.3	-0.0	0.2	0.3	-0.1	0.3	0.0	0.5	0.3	0.1	0.1	0.2
HDL Cholesterol	0.0	0.0	0.2	-0.0	0.1	0.0	-0.1	0.2	-0.1	0.1	0.4	-0.0	-0.2	-0.1
Primary Biliary Cirrhosis	0.0	0.0	0.2	0.2	0.1	-0.1	0.2	0.4	0.1	-0.1	0.0	0.2	0.4	-0.0
Blood Platelet Count	0.0	0.1	0.3	0.2	0.5	0.2	0.1	0.5	0.3	0.5	0.2	0.2	0.4	0.5
Heel T-Score	0.0	0.2	1.0	-0.1	-0.0	-0.2	-0.2	-0.5	-0.2	-0.1	0.9	-0.2	-1.0	-0.1
Height	0.0	0.4	0.9	0.4	1.0	0.8	0.7	0.0	0.4	0.7	0.2	0.4	0.3	0.8
Respiratory disease	0.0	0.1	0.3	0.2	0.2	0.2	0.5	0.1	0.1	0.0	0.6	0.1	-0.4	0.4
Hair Pigment	0.0	0.1	0.5	0.1	0.2	0.1	0.2	0.7	0.1	-0.0	0.2	0.0	0.4	0.1
Average weekly spirits intake	0.0	0.0	0.1	-0.1	-0.3	-0.1	0.1	-0.4	-0.1	-0.0	0.3	-0.1	-0.0	-0.2
Age when periods started (menarche)	0.0	0.0	0.1	0.0	-0.0	-0.2	-0.3	0.0	-0.0	0.1	0.2	0.0	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.4	0.4	-0.1	-0.4	0.2	-0.4	0.3	-0.0	0.3	0.4	-0.6	-0.0
Trunk fat mass	0.0	0.1	0.2	0.5	0.0	0.0	0.3	0.1	0.4	-0.5	0.4	0.3	-0.2	-0.0
Forced vital capacity (FVC)	0.0	0.1	0.6	0.0	-0.3	-0.1	0.2	-0.3	0.0	0.8	0.1	0.1	-0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.3	0.4	0.2	-0.0	0.6	0.1	0.4	0.2	0.5	0.4	-0.1	0.2
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.1	-0.2	-0.1	-0.4	-0.0	0.1	-0.2	0.2	-0.3	-0.2	-0.3	-0.2
Arm fat percentage (right)	0.0	0.1	0.6	0.2	-0.4	-0.2	0.2	0.2	0.1	-0.8	-0.1	0.1	-0.0	-0.3
Worrier / anxious feelings	0.0	0.1	0.3	-0.2	0.2	0.3	0.1	0.2	-0.1	0.5	0.2	-0.1	-0.1	0.0
Asthma	0.0	0.0	0.1	-0.1	-0.2	0.1	0.3	0.1	-0.1	-0.1	0.1	-0.1	-0.3	-0.1
Arm fat mass (right)	0.0	0.1	0.8	0.1	-0.4	-0.3	0.1	-0.0	0.0	-0.9	-0.1	0.0	-0.3	-0.5
Peak expiratory flow (PEF)	0.0	0.1	0.6	-0.0	-0.1	-0.1	-0.3	0.4	-0.1	0.3	0.8	-0.0	-0.4	-0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.2	-0.1	-0.1	0.1	-0.5	0.0	-0.1	0.2	-0.1	-0.1	-0.2	0.0
Medication: Amlodipine	0.0	0.0	0.1	-0.1	-0.3	0.2	0.2	0.0	-0.1	0.0	0.2	-0.1	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.5	0.0	0.1	-0.1	0.0	-0.0	0.1	-0.7	-0.1	-0.0	0.1	0.1
Age at first live birth	0.0	0.1	0.3	-0.2	-0.2	0.0	-0.0	-0.0	-0.2	-0.1	-0.5	-0.2	-0.3	-0.3
Heart disease (mother)	0.0	0.1	0.3	0.1	-0.0	-0.3	-0.1	0.2	0.1	-0.3	-0.2	0.1	-0.6	-0.0
Whole body fat mass	0.0	0.1	0.2	0.4	-0.0	-0.1	0.3	0.1	0.4	-0.5	0.2	0.3	-0.2	-0.1
Leg fat mass (right)	0.0	0.1	0.3	0.4	-0.1	-0.3	0.3	0.2	0.3	-0.5	-0.1	0.3	-0.3	-0.2
Alcohol intake frequency.	0.0	0.1	0.4	-0.2	0.2	-0.5	-0.2	0.0	-0.1	-0.4	-0.3	-0.2	-0.6	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	-0.3	-0.3	-0.0	0.1	-0.2	-0.2	-0.0	-0.3	-0.2	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.2	-0.1	0.1	-0.0	0.1	-0.2	-0.1	-0.1	0.5	-0.2	-0.5	0.1
Arm fat percentage (left)	0.0	0.1	0.5	0.3	-0.2	-0.1	0.2	0.3	0.2	-0.7	0.0	0.2	0.1	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.1	-0.2	-0.3	-0.3	-0.2	0.1	-0.3	0.3	-0.2	-0.2	-0.3	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	0.2	0.1	0.2	0.2	-0.0	0.3	0.1	-0.4	0.2	0.3	0.2
Asthma (self-reported)	0.0	0.0	0.1	0.0	-0.0	0.0	0.4	0.1	-0.0	-0.1	0.2	-0.0	-0.2	0.1
Arm fat mass (left)	0.0	0.1	0.7	0.1	-0.2	-0.3	0.1	-0.0	0.1	-0.9	0.0	-0.0	-0.3	-0.3
Medication: Bendroflumethiazide	0.0	0.1	0.6	-0.1	-0.0	0.3	0.1	0.4	0.0	0.0	-0.2	-0.0	0.8	0.0
Leg fat percentage (left)	0.0	0.1	0.2	0.5	-0.2	0.0	0.4	0.5	0.4	-0.5	-0.1	0.4	0.1	-0.2
Arm fat-free mass (left)	0.0	0.2	0.9	-0.3	-0.3	-0.4	-0.2	-0.6	-0.3	-0.6	0.0	-0.4	-1.0	-0.6
Risk taking	0.0	0.1	0.3	0.2	0.1	0.1	0.6	-0.3	0.2	0.0	-0.2	0.2	-0.0	-0.0
Leg fat mass (left)	0.0	0.1	0.5	0.1	-0.4	-0.4	0.1	-0.1	0.0	-0.7	-0.3	0.0	-0.4	-0.4

Hub : Genes

BET1

Models

Trait associations