TWAS hub - BMS1P5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.156	0.0560	9.6e-04	0.023	NA	0.020	NA	0.021	1.9e-02	NA	2.8e-02	NA	2.4e-02
2	GTEx	Artery Tibial	0.105	0.0416	6.4e-03	0.000	NA	0.006	NA	0.005	3.3e-01	NA	9.8e-02	NA	1.1e-01
3	GTEx	Brain Cerebellar Hemisphere	0.371	0.1100	2.6e-03	0.132	NA	0.123	NA	0.134	2.9e-04	NA	4.8e-04	NA	2.7e-04
4	GTEx	Brain Cerebellum	0.232	0.0820	3.7e-03	0.150	NA	0.034	NA	0.094	3.4e-05	NA	3.6e-02	NA	1.0e-03
5	GTEx	Brain Frontal Cortex BA9	0.351	0.1024	1.5e-03	0.152	NA	0.165	NA	0.110	7.9e-05	NA	3.8e-05	NA	7.8e-04
6	GTEx	Brain Nucleus accumbens basal ganglia	0.275	0.1000	6.2e-03	0.107	NA	0.101	NA	0.109	8.5e-04	NA	1.2e-03	NA	7.5e-04
7	GTEx	Brain Putamen basal ganglia	0.273	0.0920	3.6e-03	0.199	NA	0.006	NA	0.056	1.8e-05	NA	2.3e-01	NA	1.9e-02
8	GTEx	Cells Transformed fibroblasts	0.101	0.0420	3.4e-03	0.023	NA	0.011	NA	0.024	7.1e-03	NA	4.9e-02	NA	5.7e-03
9	GTEx	Liver	0.222	0.0810	5.1e-03	0.020	NA	0.032	NA	0.036	8.9e-02	NA	4.5e-02	NA	3.6e-02
10	GTEx	Nerve Tibial	0.152	0.0451	3.1e-05	0.012	NA	0.047	NA	0.022	4.6e-02	NA	3.0e-04	NA	1.0e-02
11	GTEx	Skin Sun Exposed Lower leg	0.107	0.0470	6.1e-03	0.054	NA	0.032	NA	0.042	2.9e-05	NA	1.0e-03	NA	1.9e-04
12	GTEx	Testis	0.139	0.0620	7.3e-03	0.084	NA	-0.002	NA	0.126	1.4e-04	NA	4.0e-01	NA	3.3e-06
13	GTEx	Thyroid	0.142	0.0450	1.5e-04	0.118	NA	0.108	NA	0.118	2.7e-09	NA	1.4e-08	NA	2.7e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Medication: Omeprazole (e.g. Zanprol)	4.9	5.9	9.0	-2.4	-3.0	-2.7	-2.4	-2.6	-2.7	-2.3	-1.7	-1.9	-2.8	-2.4	-2.3	-2.2
Average weekly fortified wine intake	4.2	5.0	7.0	2.0	2.3	2.2	2.3	2.6	2.6	2.1	1.4	2.6	1.6	2.2	2.2	2.5
Medication: Omeprazole	4.1	4.9	10.0	-2.5	-2.8	-2.3	-2.2	-2.1	-2.3	-1.9	-1.2	-1.5	-3.2	-2.0	-2.4	-1.9
Illnesses of father: High blood pressure	4.0	5.0	11.1	2.0	1.8	2.0	2.0	3.3	1.7	2.1	2.0	2.7	2.2	2.3	1.9	2.3
Type 2 Diabetes (T2D) (2012)	3.8	4.4	5.7	2.4	1.4	2.3	2.2	2.1	2.4	2.1	1.5	2.1	1.7	2.1	2.4	2.1
Frequency of depressed mood in last 2 weeks	3.7	5.2	10.5	-2.0	-1.8	-2.3	-2.2	-2.1	-1.8	-2.6	-3.2	-2.5	-2.0	-2.6	-1.7	-2.3
Diabetes (father)	3.5	4.3	7.5	1.6	-0.3	2.3	2.5	1.4	2.3	2.6	2.7	2.2	0.5	2.4	2.0	2.4
Medication: Paracetamol	3.5	5.8	7.2	2.1	2.5	2.3	2.5	2.7	2.5	2.6	2.4	2.2	2.3	2.3	2.4	2.5
Neck or shoulder pain in last month	3.5	4.9	7.0	2.6	1.9	2.0	2.4	1.2	2.1	2.4	2.4	2.1	2.2	2.2	2.6	2.3
Comparative height size at age 10	3.3	18.3	28.3	3.6	2.6	4.8	4.9	4.1	5.3	4.9	4.5	4.4	0.9	4.7	4.2	4.8
Medication: Simvastatin	3.1	4.6	7.7	-0.8	-2.8	-2.5	-2.2	-1.8	-2.3	-2.3	-2.4	-2.3	-1.8	-2.4	-1.5	-2.2
Noisy workplace	3.1	3.9	7.5	2.7	1.0	1.8	2.0	1.2	2.1	1.9	1.7	2.3	1.5	2.0	2.5	2.1
Loud music exposure frequency	2.9	3.2	10.8	2.7	2.2	0.8	0.9	3.3	0.5	0.9	0.7	0.9	2.9	1.1	1.8	0.9
Guilty feelings	2.9	4.3	7.9	2.4	1.1	2.5	2.2	2.4	2.8	2.2	1.2	1.9	0.8	1.7	2.5	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.3	7.7	-1.0	-2.8	-1.9	-1.6	-2.5	-1.4	-1.8	-2.1	-0.9	-2.5	-1.5	-1.0	-1.3
Sitting height	2.7	19.0	25.5	4.4	2.3	4.4	4.8	4.8	5.0	4.7	4.5	4.7	0.9	4.4	4.7	4.9
Medication for hormone replacement therapy	2.6	2.9	5.2	-0.9	-0.2	-1.9	-2.0	-0.9	-1.9	-2.1	-2.3	-2.1	0.1	-2.0	-1.4	-2.1
Had other major operations	2.5	3.1	5.7	-1.3	-0.4	-2.3	-2.3	-1.1	-2.0	-1.9	-1.4	-1.7	-0.3	-2.4	-1.9	-2.1
Mouth/teeth dental problems: Loose teeth	2.5	2.9	4.5	1.8	1.0	1.8	2.0	1.5	1.8	1.8	1.2	2.1	0.3	2.0	1.9	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	4.6	2.1	0.7	2.0	1.9	1.2	2.0	1.9	1.6	1.2	1.0	1.7	2.1	1.7
Heart attack/myocardial infarction (self-reported)	2.4	3.1	6.2	-0.1	-1.9	-2.5	-1.6	-2.3	-2.2	-1.9	-1.9	-1.5	-1.8	-1.3	-0.7	-1.6
Bilateral oophorectomy (both ovaries removed)	2.2	2.6	5.8	1.5	0.4	1.5	1.7	1.3	1.4	2.0	2.4	1.6	1.3	1.5	1.6	1.7
Ever depressed for a whole week	2.2	2.8	6.2	-0.8	-0.6	-1.9	-1.7	-1.4	-2.0	-2.1	-2.5	-2.0	-0.6	-1.5	-1.2	-1.9
Ever used hormone-replacement therapy (HRT)	2.1	2.6	6.1	-0.8	-0.8	-2.5	-1.8	-1.8	-2.3	-1.8	-1.4	-1.3	0.1	-1.8	-1.2	-1.7
Cholesterol lowering medication	2.1	3.1	8.1	-1.2	-2.8	-1.6	-1.6	-1.1	-1.6	-1.5	-1.9	-1.7	-2.1	-1.9	-1.4	-1.6
Had menopause	2.0	2.5	5.2	-0.6	-0.8	-2.1	-1.7	-2.3	-2.0	-1.9	-2.1	-1.3	-0.2	-1.6	-1.0	-1.6
Breastfed as a baby	2.0	2.5	4.4	-2.1	-1.6	-1.6	-1.6	-1.0	-1.9	-1.3	-1.0	-1.4	-1.1	-1.9	-2.1	-1.6
Neuroticism (2016)	1.9	2.7	8.1	-0.7	-2.0	-2.1	0.0	-1.3	-1.6	-2.2	-2.8	-2.3	-1.9	0.0	-0.9	0.0
Systolic blood pressure, automated reading	1.9	5.4	9.9	2.6	0.5	2.5	2.4	3.1	2.4	2.5	2.3	2.3	1.1	2.5	2.4	2.4
Medication: Levothyroxine sodium	1.9	3.2	8.6	2.0	2.2	1.6	1.2	2.8	1.4	1.3	0.4	1.6	2.9	1.3	1.8	1.4
Heart attack	1.9	2.5	5.3	0.1	-1.7	-2.3	-1.4	-2.0	-2.0	-1.8	-1.7	-1.4	-1.5	-1.2	-0.5	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	9.7	-0.6	-2.1	-1.6	-1.1	-3.1	-1.6	-1.5	-1.9	-0.9	-1.6	-1.1	-0.6	-1.0
Qualifications: A levels/AS levels or equivalent	1.8	3.9	6.2	1.5	1.5	2.5	2.2	1.7	2.2	2.3	2.0	2.0	1.3	2.2	1.8	2.2
Height	1.7	32.6	46.8	4.8	4.4	6.4	6.3	5.4	6.8	6.4	6.1	6.3	1.7	5.8	5.6	6.4
Medication: Cholesterol lowering	1.7	2.7	5.6	0.6	-0.8	-2.4	-1.7	-1.8	-2.0	-2.1	-2.2	-1.7	-0.5	-1.5	-0.4	-1.8
Medication for cholesterol	1.7	2.6	5.2	1.1	1.6	1.8	1.6	1.0	1.6	1.8	2.3	1.8	1.5	1.8	1.2	1.7
Medication: Gliclazide	1.7	1.9	3.2	1.1	-0.2	1.8	1.4	1.8	1.5	1.7	1.4	1.0	1.0	1.3	1.3	1.3
Eye problems/disorders: Glaucoma	1.7	2.0	5.5	1.7	2.0	0.9	1.0	2.3	1.3	0.8	1.0	0.9	2.0	1.3	1.3	1.0
Diastolic blood pressure, automated reading	1.7	5.2	8.0	2.8	-0.1	1.9	2.4	2.8	2.4	2.4	2.1	2.5	0.7	2.4	2.8	2.5
Reaction Time	1.6	3.0	4.5	1.6	1.6	1.3	2.0	1.4	1.5	1.7	1.4	2.1	1.8	1.9	2.0	2.1
Lupus	1.6	2.4	5.1	0.2	-0.2	2.0	1.8	1.1	2.3	1.9	1.9	1.7	-0.5	1.9	0.8	1.8
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	6.0	0.5	0.5	1.7	1.4	1.4	1.3	1.9	2.5	1.7	-0.5	1.4	0.7	1.5
Chronic bronchitis/emphysema (mother)	1.6	1.9	5.6	2.4	0.6	1.0	1.5	1.0	1.3	1.1	0.4	1.2	0.9	1.5	2.2	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	3.0	1.7	1.3	1.2	1.1	1.3	1.1	1.0	0.7	1.7	1.2	1.6	1.6	1.3
Family relationship satisfaction	1.5	1.9	8.6	-0.9	-1.3	-1.1	-1.1	-1.0	-1.2	-1.3	-1.6	-0.9	-2.9	-1.2	-1.1	-1.0
Financial situation satisfaction	1.5	1.9	3.1	1.0	-0.0	1.5	1.6	1.0	1.7	1.6	1.5	1.5	-1.1	1.3	1.3	1.6
High cholesterol (Self-reported)	1.5	2.7	5.0	-0.6	-1.4	-1.8	-1.7	-1.7	-1.9	-1.7	-1.7	-2.2	-0.8	-1.6	-1.2	-1.9
Trunk fat percentage	1.4	5.6	13.4	3.7	-0.1	1.6	2.6	1.9	2.0	2.4	2.0	2.6	1.0	2.6	3.3	2.7
Trunk fat mass	1.4	6.0	12.2	3.5	-0.2	1.9	2.8	2.1	2.3	2.6	2.1	2.7	0.6	2.6	3.4	2.8
Medication for pain relief, constipation, heartburn	1.4	2.5	4.8	-1.3	-0.6	-1.3	-1.7	-1.3	-1.5	-1.9	-2.2	-2.1	-0.4	-1.7	-1.6	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	3.0	-0.9	-1.0	-1.7	-1.5	-1.1	-1.7	-1.5	-0.8	-1.2	0.5	-1.5	-1.1	-1.4
Mother’s age at death	1.4	1.8	6.5	-0.6	-0.6	-1.8	-1.2	-2.5	-1.3	-1.5	-1.6	-1.4	0.3	-1.0	-0.6	-1.3
Ever had prostate specific antigen (PSA) test	1.4	1.6	3.0	-1.3	-0.3	-1.6	-1.4	-1.7	-1.7	-1.4	-0.8	-1.0	-0.6	-1.1	-1.5	-1.3
Alzheimer’s Disease (in father)	1.3	1.4	4.4	-0.8	-1.4	-1.5	-0.8	-2.1	-1.2	-1.0	-0.5	-1.0	-1.5	-0.8	-0.9	-0.9
Fasting Glucose	1.3	1.5	11.2	-0.9	-3.4	-0.2	-0.3	-1.1	-0.5	-0.4	-0.9	-0.8	-2.0	-0.7	-0.6	-0.4
Standing height	1.3	13.2	20.0	2.8	2.7	3.9	4.0	3.9	4.5	4.1	4.0	3.7	1.5	3.7	3.3	4.0
Blood clot in the leg (DVT)	1.3	1.7	2.8	-0.8	-1.7	-1.1	-1.3	-1.4	-1.3	-1.3	-1.3	-1.2	-1.6	-1.2	-1.1	-1.3
Loneliness, isolation	1.3	1.8	5.6	-0.8	-0.3	-1.5	-1.3	-1.1	-0.9	-1.8	-2.4	-1.3	-1.2	-1.6	-0.7	-1.3
Systolic Blood Pressure	1.2	6.1	13.3	3.1	-0.4	2.4	2.4	3.6	2.4	2.5	2.6	2.5	0.6	2.6	2.6	2.5
Heart disease (mother)	1.2	1.4	3.1	0.8	-0.7	1.3	1.5	0.1	1.4	1.5	1.8	1.1	-0.3	1.5	1.0	1.4
Whole body fat mass	1.2	5.0	10.8	3.3	-0.3	1.7	2.6	1.9	2.2	2.4	1.8	2.4	0.4	2.4	3.2	2.6
Chest pain or discomfort	1.2	1.7	3.0	-0.1	-0.5	-1.6	-1.4	-1.0	-1.6	-1.6	-1.7	-1.6	-0.6	-1.5	-0.7	-1.5
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	3.1	-0.8	-1.7	-1.0	-1.2	-1.3	-1.1	-1.2	-1.2	-1.1	-1.6	-1.2	-1.0	-1.2
HDL Cholesterol	1.1	1.9	3.4	-1.3	-0.5	-1.6	-1.7	-0.9	-1.8	-1.4	-0.7	-1.4	-0.3	-1.5	-1.7	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	4.9	-0.9	-0.7	-2.2	-1.8	-1.2	-1.9	-1.9	-2.0	-1.8	-0.6	-1.9	-1.2	-1.8
Prospective memory result	1.1	1.3	8.4	0.3	2.4	0.2	0.0	1.6	0.1	0.1	-0.2	-0.1	2.9	0.3	0.1	-0.1
Body fat percentage	1.1	4.5	11.8	3.4	-0.4	1.3	2.3	1.6	1.7	2.1	1.6	2.2	0.8	2.3	3.1	2.4
Eye problems/disorders: None of the above	1.1	1.3	3.9	-0.8	-1.8	-0.5	-0.7	-1.6	-1.0	-0.7	-1.0	-1.1	-2.0	-1.0	-0.8	-0.9
Ever had bowel cancer screening	1.1	1.3	3.2	1.8	-0.5	0.5	1.2	-1.2	0.6	1.0	1.2	1.3	0.1	1.5	1.4	1.3
Medication: Paracetamol	1.1	1.7	3.5	1.0	1.9	1.1	1.2	1.8	1.1	1.4	1.4	0.7	1.6	1.1	1.1	1.1
LDL Cholesterol	1.0	1.7	5.3	-0.7	-1.6	-1.1	-1.0	-1.8	-1.0	-1.2	-1.6	-0.5	-2.3	-1.0	-0.7	-0.9
Rheumatoid Arthritis	1.0	1.4	2.5	0.4	0.8	1.4	1.3	0.5	1.6	1.5	1.4	1.4	0.9	1.2	1.0	1.4
Serious illness, injury or assault to yourself	1.0	1.2	2.7	-0.6	-0.0	-1.2	-1.2	0.6	-1.2	-1.2	-1.4	-1.6	0.3	-1.3	-0.9	-1.3
Hearing difficulty/problems with background noise	1.0	1.6	4.6	-1.0	-0.9	-1.0	-1.3	-1.0	-1.1	-1.2	-1.2	-1.2	-2.1	-1.4	-1.1	-1.2
Depression (self-reported)	1.0	1.2	3.1	-0.7	-0.7	-1.2	-1.2	0.0	-1.2	-1.3	-1.8	-1.2	-0.3	-1.2	-0.9	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.0	5.1	-2.3	-0.9	-0.9	-1.4	-1.4	-1.5	-1.1	-0.5	-1.7	-0.6	-1.3	-2.1	-1.5
Tinnitus: Yes, now most or all of the time	1.0	1.2	1.9	0.0	-1.4	-1.3	-1.1	-1.1	-1.3	-1.2	-1.1	-1.2	-0.9	-0.8	-0.7	-1.1
Mean Putamen Volume	0.9	1.0	2.3	1.0	1.4	0.9	1.0	0.7	1.0	1.1	1.5	0.6	0.6	1.1	0.8	0.9
HbA1C	0.9	1.0	3.5	-0.8	-1.9	-0.4	-0.6	-1.0	-0.6	-0.5	-1.3	-1.3	-1.1	-1.1	-0.8	-0.8
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	2.2	1.0	0.8	1.4	1.4	0.7	1.5	1.4	1.1	1.3	1.1	1.2	1.2	1.4
Glaucoma (self-reported)	0.9	1.0	3.9	1.2	1.4	0.6	0.5	2.0	0.7	0.5	0.9	0.2	1.6	0.7	0.7	0.5
Leg pain on walking	0.9	1.2	8.6	0.2	-2.9	0.4	0.5	-1.4	0.4	0.3	-0.0	0.1	-1.9	0.4	0.4	0.4
Mineral and other dietary supplements	0.9	1.2	2.4	1.0	0.9	0.9	1.2	1.6	1.3	1.0	0.8	1.3	0.5	1.2	1.1	1.2
Number of self-reported non-cancer illnesses	0.9	1.5	4.7	0.0	-0.9	-1.6	-1.3	-1.1	-1.1	-1.6	-2.2	-1.0	-0.9	-1.2	-0.3	-1.2
Taking other prescription medications	0.8	1.3	3.2	-0.6	-1.1	-1.1	-1.0	-1.8	-1.0	-1.1	-1.4	-1.2	-1.1	-1.0	-0.4	-1.1
Weight	0.8	4.0	6.4	2.3	-0.3	1.8	2.4	1.6	2.3	2.3	1.8	2.0	-0.5	2.1	2.5	2.3
Falls in the last year	0.8	1.1	2.2	-0.3	-1.5	-0.7	-0.9	-1.5	-0.7	-0.9	-1.2	-1.1	-1.1	-1.1	-0.6	-1.0
Tense / ‘highly strung’	0.8	1.3	3.8	-0.2	-0.7	-1.3	-1.1	-1.9	-0.9	-1.4	-1.6	-1.1	-0.7	-1.1	-0.5	-1.1
Mean time to correctly identify matches	0.8	1.5	4.8	1.3	1.9	0.1	1.0	1.1	0.5	0.5	0.5	1.2	2.2	1.1	1.4	1.1
Pulse rate, automated reading	0.8	2.7	5.2	1.3	1.1	1.9	2.0	1.3	2.3	1.7	1.0	1.5	0.7	1.9	1.8	1.9
Hypertension (Self-reported)	0.8	2.4	3.9	2.0	0.6	1.6	1.6	1.8	1.7	1.5	0.9	1.5	1.0	1.7	1.9	1.6
Long-standing illness, disability or infirmity	0.8	1.2	2.9	-0.6	-1.2	-1.0	-1.0	-0.8	-0.9	-1.0	-1.3	-1.1	-1.7	-1.2	-0.7	-1.0
Friendships satisfaction	0.8	1.0	3.3	-1.4	-1.1	-0.7	-0.7	-0.4	-0.8	-0.9	-1.1	-0.6	-1.8	-0.8	-1.1	-0.6
Breast cancer (self-reported)	0.8	0.9	1.3	1.1	1.0	0.9	1.1	0.9	1.0	1.0	0.9	0.7	0.8	1.2	1.1	1.0
Prostate Cancer	0.7	1.0	2.2	0.7	0.9	1.5	1.0	1.2	1.1	1.1	0.9	1.2	-0.2	1.0	0.7	1.1
Blood White Count	0.7	5.0	7.0	-1.8	-1.8	-2.6	-2.4	-1.9	-2.6	-2.5	-2.4	-2.4	-1.0	-2.4	-2.2	-2.4
Hearing difficulty/problems: Yes	0.7	1.1	3.9	2.0	0.7	0.3	0.9	1.5	0.5	0.8	0.9	1.1	0.2	0.9	1.5	1.0
Illnesses of siblings	0.7	1.1	4.0	-0.7	2.0	-0.3	-0.7	1.1	-0.5	-0.6	-0.4	-1.0	1.9	-0.6	-0.8	-0.8
Father’s age at death	0.7	0.9	1.4	-0.7	0.1	-1.1	-1.0	-1.2	-0.9	-1.2	-1.0	-1.1	-0.0	-1.1	-0.8	-1.0
Medication: Lansoprazole	0.7	0.8	1.8	0.0	-0.8	-1.1	-0.9	-1.3	-1.0	-1.1	-1.3	-0.2	-0.6	-0.9	-0.1	-0.7
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.3	-0.5	-0.3	-1.2	-0.9	-1.0	-0.8	-1.3	-1.5	-1.0	-0.7	-0.6	-0.4	-0.9
Comparative body size at age 10	0.7	2.0	5.5	-0.6	-2.3	-1.3	-0.8	-2.3	-1.2	-0.9	-1.1	-1.2	-2.3	-0.9	-0.6	-0.9
Number of children fathered	0.7	0.8	1.6	1.2	-0.1	0.7	1.0	0.1	0.9	1.1	1.2	0.5	0.5	1.0	1.3	0.9
Medication: Ibuprofen	0.7	0.9	3.3	-0.2	1.0	1.2	0.6	1.8	0.7	1.0	1.5	0.7	-0.6	0.5	-0.1	0.6
Leg fat mass (right)	0.7	2.6	6.9	2.6	-0.6	1.1	1.8	1.3	1.5	1.6	1.0	1.6	-0.2	1.7	2.5	1.8
Knee pain experienced in last month	0.7	1.2	2.2	0.7	-0.4	1.1	1.3	0.6	0.9	1.5	1.3	1.4	-0.1	1.2	1.1	1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.2	1.0	-0.5	0.5	1.4	-0.1	1.1	1.4	1.5	1.2	0.2	1.3	1.1	1.3
Arm fat mass (left)	0.7	2.7	5.7	2.4	-0.9	1.3	1.9	0.9	1.6	1.8	1.3	1.6	-0.4	1.7	2.4	1.9
Wears glasses or contact lenses	0.7	0.8	2.1	-0.1	-1.4	-1.5	-0.7	-0.7	-0.9	-0.9	-0.9	-0.1	-1.3	-0.7	-0.2	-0.5
Irritability	0.7	1.2	2.2	1.3	1.3	1.1	1.1	0.8	1.3	1.0	0.2	1.4	0.9	0.9	1.5	1.2
Impedance of whole body	0.7	3.3	10.5	1.9	2.8	1.1	1.2	2.3	1.1	1.2	1.6	1.4	3.2	1.5	1.4	1.3
Leg fat mass (left)	0.7	2.9	7.7	2.8	-0.6	1.2	2.0	1.2	1.6	1.7	1.0	1.7	0.0	1.7	2.7	1.9
Depression (Nagel 2018)	0.6	0.9	2.9	-0.4	-0.2	-1.0	-0.9	0.1	-0.5	-1.2	-1.7	-1.1	-1.0	-1.2	-0.4	-1.0
Ovarian Cancer	0.6	0.8	3.8	-1.1	1.9	-0.1	-0.8	0.8	-0.3	-0.3	0.7	-0.6	1.2	-0.7	-1.1	-0.7
Average weekly spirits intake	0.6	0.7	1.0	-0.7	-1.0	-0.9	-0.9	-0.7	-0.3	-1.0	-0.9	-0.9	-0.6	-1.0	-0.7	-0.9
Pack years adult smoking proportion	0.6	0.9	1.6	-0.5	-0.6	-1.0	-1.2	0.0	-1.2	-1.2	-1.2	-1.3	0.1	-1.2	-0.8	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.2	-0.0	-1.3	-0.5	-0.4	-1.0	-0.3	-0.8	-1.8	-0.7	-1.3	-0.6	0.2	-0.5
Hayfever, allergic rhinitis or eczema	0.6	1.4	3.0	0.5	-0.4	1.7	1.4	0.9	1.7	1.3	1.4	0.7	-0.7	1.4	0.8	1.2
Past tobacco smoking	0.6	1.1	3.0	-1.6	-0.6	-0.5	-0.8	-1.7	-0.8	-0.5	0.1	-1.4	-0.5	-0.8	-1.4	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.4	-1.1	0.1	-1.5	-1.4	-0.7	-1.3	-1.3	-1.0	-1.3	-0.0	-1.6	-1.2	-1.4
Qualifications: None of the above	0.6	1.3	2.7	0.9	-1.4	0.9	1.4	0.7	1.1	0.9	0.3	1.3	-1.3	1.6	1.2	1.4
Impedance of arm (right)	0.6	2.9	8.7	1.4	2.7	1.1	1.1	2.4	0.9	1.3	2.0	1.1	2.9	1.5	1.0	1.2
Hair/balding pattern: Pattern 3	0.6	0.9	2.4	-1.2	-0.9	-0.7	-0.9	-1.5	-1.0	-0.9	-0.7	-0.7	-0.8	-0.8	-0.8	-0.8
Pulse rate	0.6	1.1	2.4	1.3	1.5	1.1	1.0	0.8	1.3	0.8	0.1	0.7	0.8	1.0	1.3	0.9
Impedance of arm (left)	0.6	2.8	8.2	1.4	2.5	1.1	1.2	2.2	1.0	1.3	1.9	1.2	2.9	1.5	1.0	1.2
Arm fat mass (right)	0.6	2.4	5.2	2.3	-0.9	1.1	1.9	0.9	1.5	1.7	1.3	1.5	-0.4	1.7	2.3	1.8
Length of working week for main job	0.6	0.6	2.8	-0.2	-1.2	-0.7	-0.5	-1.7	-0.9	-0.4	-0.1	-0.8	-0.9	-0.6	-0.5	-0.6
Pulse wave reflection index	0.6	0.7	2.3	-0.2	-1.5	-1.2	-0.9	-0.3	-1.0	-1.0	-0.8	-0.5	-0.4	-0.8	-0.6	-0.7
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.2	-0.5	0.4	1.2	1.0	0.6	1.0	1.2	1.4	1.5	-0.4	0.9	0.2	1.2
High blood pressure (siblings)	0.6	0.9	1.6	0.6	-1.3	0.8	1.0	-1.1	0.8	1.1	0.9	0.8	-0.4	1.0	0.9	1.0
Leg fat percentage (right)	0.6	2.0	6.8	2.6	-0.7	0.8	1.6	0.8	1.1	1.3	0.7	1.3	-0.1	1.4	2.4	1.5
Number of full brothers	0.6	0.7	5.6	0.7	-2.4	-0.6	0.1	-0.9	-0.6	-0.2	-0.5	0.3	-0.8	0.1	0.6	0.2
Worry too long after embarrassment	0.6	1.0	2.9	0.5	0.7	1.7	1.0	0.7	1.4	1.2	0.9	1.1	0.5	0.9	0.8	1.0
Pulse wave peak to peak time	0.6	0.6	2.6	0.1	1.6	0.6	0.6	0.6	0.4	0.6	0.9	0.4	1.5	0.7	0.4	0.6
Alcohol intake frequency.	0.6	1.5	2.2	-1.4	-1.0	-1.2	-1.2	-1.0	-1.1	-1.2	-1.1	-1.3	-1.1	-1.5	-1.5	-1.2
Had major operations	0.6	0.7	1.2	1.1	0.4	0.8	1.0	0.5	0.9	0.8	1.0	0.5	1.0	1.0	0.9	0.9
Osteoarthritis (self-reported)	0.6	0.8	4.3	-0.2	-0.9	0.6	0.7	-0.3	0.3	0.9	1.0	1.1	-2.1	0.8	0.1	0.8
Leg fat percentage (left)	0.6	2.1	7.6	2.8	-0.6	0.8	1.6	0.9	1.1	1.3	0.6	1.3	0.3	1.4	2.5	1.5
Pain experienced in last month	0.6	1.0	2.5	-0.3	-0.9	-1.1	-1.1	-0.1	-1.3	-1.2	-1.6	-1.2	0.1	-1.0	-0.6	-1.1
Basal cell carcinoma (self-reported)	0.6	0.8	2.0	0.2	1.2	0.4	0.7	0.9	0.6	0.8	1.4	0.6	1.4	0.9	0.3	0.7
Heart disease (siblings)	0.6	0.7	2.7	1.3	-1.6	-0.3	0.4	-0.8	0.1	-0.2	-1.0	0.1	-1.3	0.2	1.1	0.3
Depressed Affect (Nagel 2018)	0.5	1.1	2.8	-0.8	0.1	-1.0	-1.1	0.0	-0.5	-1.3	-1.7	-1.0	-1.4	-1.4	-0.6	-1.0
Alzheimer’s Disease (including proxy)	0.5	0.7	1.9	-0.2	-1.4	-1.2	-0.7	-1.1	-1.1	-0.7	-0.5	-0.7	-0.7	-0.6	-0.5	-0.7
Age at First Birth	0.5	0.7	4.9	1.2	0.7	-1.1	-0.2	-0.2	-0.9	-0.5	-0.1	0.1	2.2	0.1	0.6	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.9	1.3	-0.7	-1.4	-0.5	-0.7	-1.0	-0.7	-0.2	-0.5	0.7	-0.3	0.4	-0.5
Primary Biliary Cirrhosis	0.5	0.7	4.5	-0.7	-1.1	-0.3	-0.2	-1.3	-0.5	-0.2	-0.1	-0.1	-2.1	-0.0	-0.4	-0.1
Schizophrenia (2014)	0.5	1.1	2.9	-1.7	-1.3	-0.4	-0.9	-1.2	-1.0	-0.7	-0.4	-1.0	-0.2	-1.2	-1.3	-0.9
Lung FVC	0.5	2.3	9.1	-3.0	0.1	-0.5	-1.5	-1.3	-1.4	-1.1	-0.6	-1.6	-0.9	-0.9	-2.6	-1.5
Sensitivity / hurt feelings	0.5	0.8	2.0	0.8	0.0	1.4	0.9	1.1	1.3	0.9	0.3	0.9	0.3	0.8	1.1	0.9
Severe depression (siblings)	0.5	0.6	1.0	0.6	0.9	0.8	0.9	0.6	1.0	0.7	0.7	0.7	-0.2	1.0	0.7	0.9
Leg fat-free mass (left)	0.5	2.7	4.6	1.0	-0.7	1.8	2.0	1.3	2.2	2.1	1.7	1.6	-1.2	1.7	1.6	1.9
Current tobacco smoking	0.5	0.9	2.2	-1.1	-0.0	-0.7	-0.9	-0.9	-0.6	-0.9	-0.5	-1.5	-0.8	-1.0	-1.2	-1.1
Maternal smoking around birth	0.5	0.7	1.5	-0.1	-0.9	1.2	0.6	0.9	1.0	0.9	1.2	1.0	-0.7	0.6	0.0	0.8
Qualifications: CSEs or equivalent	0.5	0.7	3.7	-1.1	-1.3	0.5	0.1	-0.9	0.1	0.4	0.7	0.0	-1.9	-0.0	-0.7	0.0
High blood pressure	0.5	1.4	3.0	1.7	0.4	1.0	1.1	1.6	1.2	1.0	0.5	1.0	1.1	1.3	1.5	1.1
Impedance of leg (left)	0.5	2.6	8.6	1.9	2.3	1.0	1.0	1.9	1.0	1.0	1.1	1.3	2.9	1.2	1.5	1.2
Leg predicted mass (left)	0.5	2.6	4.4	1.0	-0.6	1.8	2.0	1.3	2.1	2.0	1.6	1.5	-1.2	1.6	1.5	1.9
Diabetes (self-reported)	0.5	0.8	3.1	-0.6	-0.9	-0.8	-0.7	-0.4	-0.6	-0.8	-0.9	-0.9	-1.8	-0.8	-0.7	-0.7
Fluid intelligence score	0.5	1.0	1.9	-1.1	-0.2	-0.7	-1.1	-0.3	-0.9	-1.2	-1.2	-1.4	-0.7	-0.9	-1.2	-1.2
Arm fat percentage (right)	0.5	2.1	5.2	2.3	-0.9	0.9	1.7	0.9	1.1	1.6	1.2	1.4	0.0	1.7	2.1	1.6
Time employed in main current job	0.5	0.5	2.2	-1.0	-0.5	-0.6	-0.6	-1.5	-0.8	-0.6	-0.4	-0.4	-0.2	-0.4	-0.9	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.4	0.3	-1.5	0.4	0.9	-1.1	0.7	0.7	0.4	0.6	-1.6	0.8	0.8	0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.6	1.6	1.1	0.9	0.6	1.5	0.6	0.6	0.1	0.9	1.3	0.7	1.3	0.7
Age at last live birth	0.5	0.7	1.9	0.2	0.2	1.4	1.0	0.8	1.2	1.1	0.9	0.8	0.5	0.8	0.5	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.2	0.8	1.5	1.1	1.0	1.2	0.9	1.2	1.4	0.7	0.1	0.9	0.8	0.9
Average weekly champagne plus white wine intake	0.5	0.6	1.2	0.5	0.4	1.1	0.8	0.5	0.7	1.1	0.8	0.9	1.1	0.5	0.7	0.8
Hearing aid user	0.5	0.6	1.7	0.4	1.0	1.1	0.6	1.3	1.0	0.8	0.7	0.6	0.6	0.5	0.5	0.6
Basal metabolic rate	0.5	2.7	5.0	1.1	-0.7	1.9	2.0	1.1	2.2	2.0	1.6	1.6	-1.4	1.6	1.6	1.9
Arm predicted mass (left)	0.5	2.6	5.0	1.3	-0.8	1.8	2.0	0.7	2.2	1.9	1.4	1.4	-1.6	1.5	1.8	1.8
Bipolar Disorder (2018)	0.4	0.6	1.0	-0.9	-0.1	-0.8	-1.0	-0.5	-0.9	-0.8	-0.2	-0.9	0.1	-0.9	-1.0	-1.0
Schizophrenia vs Biploar Disorder	0.4	0.5	2.2	0.0	-1.5	0.7	0.9	-0.6	0.4	0.9	0.8	0.5	-0.3	0.6	0.4	0.8
Body Mass Index (BMI) (2010)	0.4	0.6	2.2	-0.3	-1.0	0.7	0.8	-0.1	0.6	1.1	1.5	0.3	-1.1	0.4	0.1	0.6
Crohns Disease (2012)	0.4	0.7	1.5	0.0	0.6	-1.2	-0.8	-1.1	-1.1	-1.1	-1.0	-0.7	-0.3	-0.6	-0.4	-0.8
Allergy or Eczema	0.4	1.2	3.2	0.4	-0.6	1.7	1.1	0.6	1.7	1.0	0.6	0.6	-1.8	1.0	0.7	1.0
Number of treatments/medications taken	0.4	0.7	2.1	0.3	0.2	-1.1	-0.9	-0.3	-0.7	-1.1	-1.4	-1.1	0.0	-0.7	-0.0	-1.0
Supplements: Zinc	0.4	0.5	1.2	0.5	-0.3	1.0	0.8	0.5	1.1	0.8	0.0	0.5	0.3	0.5	0.8	0.7
Medication: Metformin	0.4	0.6	1.8	0.8	0.0	0.9	0.8	1.3	0.9	0.7	0.1	0.6	0.2	0.7	0.9	0.8
Impedance of leg (right)	0.4	1.7	5.0	1.5	1.9	0.8	0.9	1.6	0.9	0.9	1.2	1.2	2.2	1.1	1.2	1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.0	0.2	-0.8	-0.7	0.2	-0.4	-0.8	-1.1	-0.5	0.8	-0.7	-0.2	-0.6
Waist circumference	0.4	1.3	2.9	1.7	-0.2	0.8	1.4	1.0	1.2	1.2	0.7	1.1	-0.4	1.2	1.7	1.3
Number of incorrect matches in round	0.4	0.7	1.3	-0.5	0.0	-1.0	-0.9	-0.5	-1.0	-1.1	-1.1	-0.9	-0.8	-0.7	-0.8	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.9	-0.2	-0.3	-0.9	-0.7	-0.5	-0.4	-1.1	-1.7	-0.6	-0.6	-1.1	-0.1	-0.7
Pulse wave Arterial Stiffness index	0.4	0.5	2.4	-0.0	-1.5	-0.4	-0.4	-0.5	-0.2	-0.4	-0.7	-0.2	-1.6	-0.6	-0.3	-0.3
Exposure to tobacco smoke at home	0.4	0.5	1.5	-0.6	-0.1	-0.7	-0.6	-1.2	-0.7	-0.7	-0.4	-1.0	0.4	-0.6	-0.5	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.2	0.4	-0.6	-1.1	-0.7	-0.7	-1.0	-0.8	-1.0	-0.4	-1.1	-0.6	-0.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	0.9	0.9	0.7	0.9	0.2	0.9	0.6	0.1	0.7	0.4	0.6	1.1	0.8
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.1	-0.8	-0.5	-0.3	-0.7	0.6	-0.6	-0.6	-1.1	-0.7	-0.7	-1.0	-0.7	-0.7
Arm fat-free mass (right)	0.4	2.2	4.6	1.2	-0.6	1.7	1.8	1.0	2.2	1.8	1.2	1.4	-1.3	1.3	1.6	1.7
Exposure to tobacco smoke outside home	0.4	0.5	1.5	-0.1	0.5	1.2	0.8	0.5	1.2	0.9	0.7	0.4	0.1	0.6	0.3	0.7
Age at first live birth	0.4	0.7	2.2	0.6	0.1	0.7	0.9	0.5	0.8	0.8	0.5	0.8	1.5	0.7	0.9	0.9
Overall health rating	0.4	0.9	1.8	1.3	-0.4	0.7	1.1	0.2	0.9	1.0	0.8	1.3	-0.5	1.2	1.3	1.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.7	1.3	-1.1	0.1	0.5	-1.2	0.6	0.3	0.0	0.2	-0.3	0.3	1.1	0.4
Smoking status: Previous	0.4	0.6	2.5	1.6	0.5	-0.4	0.1	1.3	0.0	-0.3	-0.8	1.0	0.3	0.1	1.2	0.4
Whole body fat-free mass	0.4	2.3	4.4	0.6	-0.8	1.8	1.8	1.0	2.1	1.9	1.4	1.4	-1.6	1.4	1.3	1.7
Leg fat-free mass (right)	0.4	2.2	3.8	0.9	-0.5	1.7	1.8	1.3	2.0	1.9	1.4	1.4	-1.1	1.4	1.4	1.7
Arm fat percentage (left)	0.4	1.8	4.6	2.1	-1.1	0.8	1.5	0.6	0.9	1.4	1.0	1.3	-0.1	1.4	2.0	1.5
Whole body water mass	0.4	2.2	4.2	0.6	-0.9	1.7	1.7	0.8	2.1	1.8	1.4	1.3	-1.8	1.3	1.2	1.6
Leg predicted mass (right)	0.4	2.2	4.0	0.9	-0.6	1.7	1.8	1.2	2.0	1.9	1.4	1.4	-1.1	1.5	1.5	1.7
Miserableness	0.4	0.7	1.8	1.1	0.3	0.6	0.8	1.1	1.2	0.6	-0.2	1.0	0.2	0.4	1.3	0.9
Ever taken oral contraceptive pill	0.4	0.4	1.6	-0.2	-0.4	-0.9	-0.8	-0.1	-0.9	-0.6	-0.5	-0.2	-0.5	-1.3	-0.4	-0.7
Arm fat-free mass (left)	0.4	1.8	3.6	1.0	-1.0	1.4	1.6	0.5	1.9	1.6	1.0	1.3	-1.5	1.2	1.5	1.5
Fractured/broken bones in last 5 years	0.4	0.6	0.9	-0.8	0.4	-0.5	-0.9	-0.2	-0.7	-0.8	-0.9	-0.8	0.6	-0.9	-0.9	-0.8
Age started oral contraceptive pill	0.4	0.5	1.5	-0.5	-0.6	-0.9	-0.5	-1.2	-0.7	-0.9	-1.2	-0.5	0.4	-0.4	-0.4	-0.5
Unable to work because of sickness or disability	0.4	0.5	1.9	0.8	-0.7	-0.8	-0.3	-1.1	-0.3	-0.7	-1.4	-0.3	-0.7	-0.4	0.6	-0.3
Supplements: Calcium	0.4	0.5	1.4	-1.0	-0.2	-0.3	-0.8	0.1	-0.4	-0.5	-0.4	-0.8	-0.6	-1.2	-0.9	-0.8
Irritable Bowel Disease (IBD)	0.3	0.7	3.2	0.2	-0.7	-0.7	-0.4	-1.8	-0.5	-0.7	-1.0	-0.4	-1.7	-0.3	-0.1	-0.4
Cardiovascular Disease	0.3	0.9	3.1	1.8	-0.8	0.7	0.9	1.0	0.6	0.7	0.0	0.5	0.9	0.9	1.4	0.8
Angina	0.3	0.3	1.4	1.2	0.7	0.1	0.3	0.5	0.4	-0.0	-0.5	0.5	-0.4	0.4	1.0	0.4
Diabetes (mother)	0.3	0.4	1.0	-0.1	-0.7	-0.8	-0.5	0.1	-0.6	-0.6	-0.4	-0.7	-1.0	-0.6	-0.4	-0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.1	0.1	-0.4	-0.9	-0.6	-1.1	-0.8	-0.6	-0.9	-0.2	0.3	-0.5	-0.2	-0.5
Medication: Atenolol	0.3	0.3	1.0	0.5	-0.3	-0.9	-0.3	0.1	-0.8	-0.4	-0.8	0.5	1.0	-0.2	0.4	-0.0
Forced vital capacity (FVC)	0.3	1.0	2.8	-0.6	0.5	1.7	1.1	0.9	1.3	1.4	1.4	0.7	-0.5	0.9	0.1	1.0
Medication: Ramipril	0.3	0.4	1.0	-0.7	-0.4	-0.3	-0.6	-0.3	-0.3	-0.4	-0.6	-1.0	0.7	-0.7	-0.6	-0.7
Trunk fat-free mass	0.3	1.6	3.6	0.2	-0.7	1.5	1.5	0.7	1.9	1.5	1.1	1.1	-1.8	1.1	0.9	1.4
Hip circumference	0.3	1.5	2.8	1.7	-1.0	0.7	1.4	0.6	1.0	1.3	1.1	1.3	-1.0	1.3	1.6	1.4
Number of live births	0.3	0.4	3.0	-0.0	-0.5	-0.1	0.0	-1.7	-0.2	-0.1	-0.0	-0.2	-1.2	-0.1	0.2	-0.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.7	-0.5	0.6	1.7	1.0	0.8	1.3	1.4	1.5	0.7	0.1	0.8	0.1	0.9
Happiness	0.3	0.4	3.3	-0.2	-0.4	0.2	0.2	-0.8	0.4	0.0	-0.3	-0.1	-1.8	0.3	0.0	0.1
Trunk predicted mass	0.3	1.8	4.1	0.4	-0.7	1.7	1.6	0.7	2.0	1.7	1.3	1.1	-1.8	1.2	1.0	1.5
Health satisfaction	0.3	0.3	2.5	-0.4	-1.0	-0.2	-0.0	-0.5	0.1	-0.1	-0.4	-0.2	-1.6	-0.0	-0.1	-0.1
Shortness of breath walking on level ground	0.3	0.4	1.2	0.2	0.7	1.0	0.5	1.1	0.9	0.4	-0.1	-0.4	0.5	0.6	0.5	0.2
Emphysema/chronic bronchitis	0.3	0.3	1.1	0.2	0.9	-0.4	-0.2	1.1	-0.1	-0.4	-0.6	-0.5	1.1	-0.2	0.0	-0.3
Angina (self-reported)	0.3	0.4	1.5	1.2	0.9	0.2	0.4	0.8	0.5	0.1	-0.2	0.6	-0.3	0.5	1.1	0.5
Arm predicted mass (right)	0.3	1.3	2.8	0.7	-0.8	1.2	1.4	0.5	1.7	1.3	0.8	1.0	-1.6	0.8	1.2	1.2
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	-0.7	0.4	0.8	0.7	0.4	0.3	0.9	1.0	0.1	0.4	1.1	-0.3	0.5
Illnesses of father: None of the above (group 1)	0.3	0.4	0.9	-0.4	1.0	-0.3	-0.6	-0.3	-0.5	-0.5	-0.6	-0.8	0.6	-0.7	-0.4	-0.7
Commuting to job workplace: Public transport	0.3	0.4	1.3	0.2	1.2	0.7	0.5	0.8	0.4	0.4	0.2	0.3	0.9	0.7	0.3	0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	-0.2	-1.1	-0.5	-0.5	-1.0	-0.8	-0.4	-0.7	-0.8	0.2	-0.6	-0.2	-0.6
Ever smoked	0.3	0.6	1.5	1.1	0.2	0.3	0.7	1.2	0.7	0.5	-0.1	1.2	-0.2	0.7	1.1	0.9
Commuting to job workplace: Cycle	0.3	0.4	1.6	-0.4	1.2	0.1	-0.5	0.6	-0.3	-0.2	-0.5	-0.3	1.3	-0.8	-0.3	-0.4
Myopia	0.3	0.4	1.8	1.1	0.4	-0.1	0.3	1.3	0.1	0.1	0.1	-0.3	1.0	0.2	0.8	0.2
Vascular/heart problems diagnosed by doctor	0.3	0.9	3.3	-1.8	-0.4	-0.5	-0.8	-1.2	-0.7	-0.6	-0.0	-0.6	-1.1	-1.0	-1.5	-0.8
Pack years of smoking	0.3	0.4	0.9	-0.2	-0.5	-0.6	-0.7	0.2	-0.8	-0.7	-0.8	-0.9	0.2	-0.7	-0.4	-0.8
Worry (Nagel 2018)	0.2	0.4	2.6	-0.6	-0.5	-0.5	-0.5	-0.3	0.0	-0.4	-0.2	-0.4	-1.6	-0.7	-0.6	-0.4
Crohns Disease (2017)	0.2	0.4	1.7	0.9	-0.2	-0.6	-0.2	-1.3	-0.5	-0.5	-0.7	-0.1	-0.9	-0.1	0.4	-0.2
Ulcerative Colitis (UC)	0.2	0.4	2.1	0.0	-0.7	0.1	0.2	-1.3	0.3	-0.1	-0.3	-0.0	-1.4	0.2	0.1	0.1
Breast Cancer	0.2	0.5	4.5	0.1	-0.7	0.2	-0.1	-0.8	0.1	-0.0	0.3	-0.3	-2.1	-0.0	-0.1	-0.2
Bipolar Disorder (2011)	0.2	0.2	1.3	0.8	1.1	0.1	0.1	0.2	0.4	0.0	0.6	-0.3	0.1	0.3	0.3	-0.0
Triglycerides	0.2	0.3	2.1	0.3	-0.5	-0.4	0.2	-1.5	-0.4	-0.0	-0.3	-0.4	-0.4	-0.0	0.4	-0.0
Ulcerative Colitis	0.2	0.3	1.5	-0.2	-0.1	-0.4	-0.1	-1.2	0.1	-0.4	-0.6	-0.6	-0.8	-0.0	-0.1	-0.3
Blood Red Count	0.2	1.6	6.5	1.1	0.7	0.8	1.0	1.6	0.6	1.1	1.1	1.5	2.5	1.0	1.0	1.2
Hypothyroidism (self reported)	0.2	0.4	1.6	1.3	0.8	0.2	0.1	1.0	-0.0	0.0	-0.3	-0.0	0.7	0.2	0.8	0.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	4.1	0.1	-2.0	-0.1	0.3	0.3	-0.2	0.1	-0.3	0.1	-0.9	0.1	0.2	0.3
Chronotype (morning person)	0.2	0.4	1.2	-0.5	-0.2	0.7	0.4	-0.0	0.4	0.7	1.1	0.9	1.1	0.3	-0.4	0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.8	0.0	-0.8	-0.3	-0.4	-0.8	-0.3	-0.3	-0.4	-0.2	-0.9	-0.4	-0.1	-0.3
Multivitamins +/- minerals	0.2	0.3	1.5	-0.3	-0.7	-0.2	-0.3	-1.2	-0.2	-0.2	-0.5	-0.2	0.9	-0.4	-0.0	-0.2
Stomach or abdominal pain in last month	0.2	0.3	0.6	0.7	0.5	-0.5	-0.4	0.7	-0.2	-0.5	-0.7	-0.2	0.6	-0.7	0.3	-0.3
Supplements: Glucosamine	0.2	0.2	0.5	-0.7	0.3	-0.1	-0.5	-0.6	-0.1	-0.4	-0.1	-0.6	-0.3	-0.5	-0.6	-0.5
Chronic bronchitis/emphysema (father)	0.2	0.2	1.0	1.0	-0.3	-0.1	0.3	0.1	0.3	-0.0	-0.6	-0.1	-0.0	0.5	1.0	0.2
High blood pressure (mother)	0.2	0.3	1.5	1.2	-0.7	-0.5	0.2	0.1	-0.1	-0.0	-0.3	0.2	0.3	0.2	0.8	0.2
Body mass index (BMI)	0.2	0.7	2.6	1.1	-1.6	0.1	0.7	-0.2	0.4	0.5	-0.0	0.4	-1.3	0.5	1.1	0.6
Financial difficulties in last 2 years	0.2	0.3	1.6	-0.3	-0.8	0.5	0.5	0.1	0.7	0.5	0.2	0.0	-1.3	0.2	0.1	0.3
Pain all over the body in last month	0.2	0.3	1.4	-0.4	-1.2	0.1	0.3	-0.4	0.3	0.3	0.4	0.3	-0.9	0.1	-0.1	0.3
Neuroticism score	0.2	0.3	1.3	0.5	0.4	0.7	0.5	0.3	1.1	0.3	-0.5	0.5	-0.5	0.1	0.8	0.5
Mouth/teeth dental problems: Dentures	0.2	0.4	1.1	-0.1	-0.2	-1.0	-0.5	-0.2	-0.4	-0.8	-1.0	-0.9	-0.6	-0.6	-0.2	-0.6
Asthma	0.2	0.4	1.7	-1.1	-1.3	0.2	-0.1	-0.4	-0.1	-0.0	0.1	-0.1	-1.2	-0.3	-0.8	-0.1
Illnesses of mother	0.2	0.2	1.0	-1.0	0.8	0.6	-0.2	0.8	0.1	0.1	0.2	-0.1	-0.2	-0.2	-0.7	-0.1
Gout (self-reported)	0.2	0.2	1.1	-0.5	1.0	-0.4	-0.4	0.5	-0.1	-0.4	-0.3	0.2	-0.3	-0.5	-0.5	-0.2
Birth weight	0.2	0.5	1.8	-0.3	-0.9	-0.7	-0.3	-1.3	-0.4	-0.5	-1.1	-0.4	-1.2	-0.5	-0.2	-0.4
Migraine (self-reported)	0.2	0.3	0.8	0.9	0.6	-0.4	-0.1	-0.2	-0.2	-0.2	-0.8	-0.3	0.6	-0.4	0.8	-0.2
Medication: Allopurinol	0.2	0.3	1.7	-0.4	1.3	0.3	-0.0	0.9	0.4	-0.0	0.1	0.7	-0.0	-0.0	-0.2	0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.2	-0.3	-0.3	-0.2	-0.4	-0.2	-0.4	-0.9	-0.5	-0.6	-0.5	0.1	-0.3
Number of full sisters	0.2	0.3	0.8	0.4	-0.9	0.3	0.6	-0.5	0.2	0.5	0.1	0.5	-0.3	0.5	0.7	0.6
Suffer from ‘nerves’	0.2	0.3	1.2	-0.6	-0.8	-0.4	-0.4	0.3	0.0	-0.2	0.0	0.3	-1.1	-0.4	-0.6	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.9	0.3	0.4	0.0	0.2	-0.0	0.0	0.3	0.3	0.1	1.4	0.0	0.3	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.8	-0.5	0.4	0.4	0.0	0.0	-0.2	0.2	0.8	0.1	0.9	0.5	-0.6	0.0
Supplements: Vitamin C	0.2	0.3	0.7	-0.5	-0.1	-0.2	-0.6	-0.4	-0.2	-0.6	-0.4	-0.8	-0.4	-0.6	-0.8	-0.6
Illnesses of father: Heart disease	0.2	0.3	1.2	-1.1	-0.8	0.1	-0.2	-0.4	-0.2	0.0	0.2	0.2	-1.1	-0.2	-0.8	-0.1
Diabetes diagnosed by doctor	0.2	0.2	1.6	0.2	-1.0	0.1	0.2	0.5	0.2	0.0	-0.3	0.1	-1.2	0.0	0.2	0.2
Qualifications: nursing, teaching	0.2	0.4	2.2	0.7	1.5	0.2	0.2	0.5	0.5	0.1	0.2	0.1	1.0	0.3	0.4	0.2
Commuting to job workplace: Walk	0.2	0.2	1.1	-0.4	0.7	-0.0	-0.3	1.0	-0.2	-0.3	-0.8	-0.3	-0.0	-0.1	-0.3	-0.3
Eye problems/disorders: Cataract	0.2	0.3	0.9	0.3	0.8	0.1	0.2	0.9	0.4	0.0	-0.1	0.8	0.8	0.4	0.2	0.4
Osteoporosis (self-reported)	0.2	0.2	0.8	0.5	-0.0	0.3	0.3	0.6	0.3	0.2	-0.4	0.9	0.3	0.1	0.5	0.4
Medication: Aspirin	0.2	0.3	0.8	-0.4	-0.2	-0.6	-0.6	0.7	-0.5	-0.7	-0.9	0.1	-0.0	-0.5	-0.4	-0.4
Smoking status: Current	0.2	0.3	1.1	-0.8	0.3	0.0	-0.4	-0.4	-0.0	-0.3	0.1	-1.0	-0.5	-0.4	-0.8	-0.6
Medication: Bendroflumethiazide	0.2	0.3	0.8	0.1	-0.5	0.6	0.5	0.4	0.9	0.6	0.4	0.8	0.0	0.5	0.3	0.6
Alcohol drinker status: Never	0.2	0.2	0.9	-0.5	-0.2	-0.4	-0.3	-0.0	-0.3	-0.4	-1.0	-0.5	0.1	-0.5	-0.4	-0.4
Average weekly beer plus cider intake	0.2	0.3	1.5	-0.0	0.7	-0.6	-0.3	0.3	-0.2	-0.7	-1.2	0.6	-0.9	-0.1	0.1	-0.0
Risk taking	0.2	0.2	2.1	-0.1	1.4	-0.0	-0.2	0.3	-0.3	-0.1	0.1	0.2	-0.7	-0.3	-0.2	-0.1
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.5	0.6	-0.1	-0.5	0.7	-0.3	-0.2	0.2	-0.2	0.6	-0.6	-0.8	-0.3
Bipolar Disorder or Schizophrenia	0.1	0.4	0.9	-0.7	0.2	-0.4	-0.6	-0.6	-0.8	-0.5	-0.0	-0.6	1.0	-0.7	-0.6	-0.6
Neuroticism (Nagel 2018)	0.1	0.2	1.2	0.2	0.4	0.2	0.0	0.8	0.7	-0.1	-0.4	-0.1	-1.1	-0.2	0.4	0.0
Schizophrenia (2018)	0.1	0.1	1.3	-0.1	0.3	0.2	0.0	-0.3	-0.3	0.0	0.1	-0.0	1.1	-0.1	0.0	-0.0
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	0.4	-0.3	-0.2	0.0	0.2	-0.2	0.0	-0.1	0.1	0.6	0.1	0.2	0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.0	-0.1	0.3	1.0	0.4	0.8	0.7	0.5	0.1	0.0	-0.8	0.4	-0.0	0.3
Blood Eosinophil Count	0.1	0.4	1.8	0.4	-0.8	0.5	0.6	-0.6	-0.1	0.8	1.3	-0.0	-0.2	0.7	0.2	0.4
Heel T-Score	0.1	1.0	5.3	0.8	0.7	-1.4	-0.7	0.5	-0.9	-1.0	-1.0	-0.5	2.3	-0.7	0.3	-0.6
BMI	0.1	0.5	4.8	0.7	-2.2	-0.3	0.3	-0.0	-0.2	0.2	-0.4	0.1	-0.6	0.1	0.7	0.3
Waist Hip Ratio (WHR)	0.1	0.3	1.4	0.2	0.8	0.7	0.6	1.2	0.6	0.4	-0.0	-0.0	0.8	0.4	0.4	0.4
Smoking Status	0.1	0.2	1.5	0.2	0.4	-0.2	-0.2	0.4	0.1	-0.4	-0.3	-0.1	-1.2	-0.2	-0.0	-0.1
Respiratory disease	0.1	0.3	2.1	0.3	-0.1	0.6	0.4	1.4	0.5	0.5	0.6	0.6	0.2	0.2	0.2	0.5
Lung FEV1/FVC ratio	0.1	0.4	1.2	-0.3	-1.1	0.9	0.4	-0.4	0.7	0.7	1.0	0.1	-0.5	0.4	-0.3	0.3
Neuroticism	0.1	0.2	0.9	-0.1	0.0	-0.5	-0.4	0.0	0.0	-0.4	-0.7	-0.4	-0.9	-0.7	-0.1	-0.4
Tanning	0.1	1.1	2.3	-0.3	-0.5	-1.5	-1.1	-1.1	-1.5	-1.3	-1.0	-1.3	-0.3	-0.8	-0.9	-1.2
Hand grip strength (left)	0.1	0.2	0.6	-0.8	-0.7	0.3	-0.2	0.1	0.0	0.1	0.1	-0.3	0.0	-0.2	-0.7	-0.3
Ever had hysterectomy (womb removed)	0.1	0.2	0.8	-0.4	-0.0	-0.2	-0.1	-0.5	-0.3	0.3	0.9	-0.1	-0.7	-0.1	-0.4	-0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.6	0.1	0.6	0.1	-0.0	0.8	-0.0	-0.0	0.3	0.0	-0.3	0.2	-0.1	0.0
Vitamin and mineral supplements	0.1	0.1	0.5	-0.3	0.3	-0.2	-0.1	0.7	-0.1	-0.1	0.1	0.1	-0.5	-0.2	-0.3	-0.1
Medication: Co-codamol	0.1	0.1	0.8	0.1	-0.5	-0.1	-0.2	-0.5	-0.3	-0.1	-0.0	-0.2	-0.9	-0.4	0.0	-0.1
Hand grip strength (right)	0.1	0.4	2.5	-0.1	1.2	0.1	-0.2	0.9	0.1	-0.1	-0.2	-0.4	1.6	-0.2	-0.2	-0.3
Townsend deprivation index at recruitment	0.1	0.2	0.5	0.1	0.6	0.5	0.5	0.7	0.2	0.5	0.3	0.3	0.1	0.4	0.3	0.4
Fed-up feelings	0.1	0.1	0.6	0.3	0.7	0.1	0.1	0.5	0.3	-0.0	-0.7	-0.1	-0.1	-0.2	0.6	0.1
Relative age voice broke	0.1	0.2	1.0	0.1	-0.7	0.0	0.1	-1.0	-0.3	0.1	0.3	0.6	0.2	0.2	0.1	0.3
Age when periods started (menarche)	0.1	0.2	1.2	-0.1	0.7	-0.0	0.1	0.8	-0.2	0.3	0.3	-0.0	1.1	0.2	0.0	0.1
Alcohol usually taken with meals	0.1	0.2	1.1	0.5	-0.8	-0.4	-0.0	-1.1	-0.4	-0.0	0.0	-0.2	0.6	-0.1	0.3	-0.1
Nervous feelings	0.1	0.2	1.4	-0.7	-0.0	0.2	-0.2	0.2	0.5	-0.3	-0.2	-0.1	-1.2	-0.2	-0.4	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.7	0.2	0.5	-0.4	-0.3	-0.3	-0.3	-0.3	-0.8	-0.1	0.3	-0.4	0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.4	0.2	0.6	-0.1	-0.2	0.3	-0.0	-0.4	-0.6	-0.4	0.6	-0.1	0.1	-0.2
Mouth/teeth dental problems	0.1	0.1	0.7	-0.3	-0.1	0.8	0.0	0.3	0.0	0.4	0.8	0.1	0.0	0.3	-0.3	0.1
Allergy	0.1	0.2	1.2	0.3	0.9	-0.6	-0.2	-0.1	-0.6	-0.2	-0.2	0.3	1.1	-0.3	0.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	-0.2	0.3	0.1	0.1	0.7	-0.0	0.1	0.1	-0.6	0.4	0.1	-0.1	-0.1
Alcohol intake versus 10 years previously	0.1	0.2	0.6	-0.4	0.5	-0.1	-0.3	0.8	0.2	-0.4	-0.4	-0.3	-0.5	-0.0	-0.4	-0.3
Worrier / anxious feelings	0.1	0.2	0.9	-0.4	-0.0	0.8	0.2	0.3	0.7	0.4	0.2	0.4	-0.9	0.0	-0.1	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	0.1	0.2	0.1	0.1	0.4	0.1	0.3	0.2	0.6	-0.4	-0.1	0.2	0.3
Lung cancer (father)	0.1	0.2	0.5	0.2	-0.2	-0.5	-0.2	-0.5	-0.7	-0.1	0.3	-0.7	0.5	-0.2	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.4	-1.2	0.9	0.8	0.2	0.2	0.4	0.6	1.0	-0.0	-0.0	0.1	-0.7	0.1
Hair/balding pattern: Pattern 4	0.1	0.1	0.6	0.3	-0.4	0.2	0.2	0.3	0.1	0.4	0.8	0.1	-0.7	0.3	0.2	0.2
Birth weight of first child	0.1	0.2	1.7	0.4	0.7	0.1	0.2	0.4	-0.2	0.3	0.3	0.4	1.3	0.2	0.4	0.3
Peak expiratory flow (PEF)	0.1	0.3	0.8	0.4	-0.9	0.6	0.5	0.2	0.3	0.8	0.9	0.4	0.3	0.3	0.5	0.5
Headache pain in last month	0.1	0.1	0.2	0.2	0.1	0.2	0.4	0.3	0.4	0.3	0.1	0.1	0.5	0.1	0.4	0.3
Medication: Amlodipine	0.1	0.1	0.4	0.0	0.2	0.4	-0.1	0.6	0.4	-0.1	-0.2	-0.2	0.0	-0.1	-0.1	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.5	2.1	-0.9	1.4	1.0	0.5	0.5	0.6	0.8	1.0	0.1	0.2	0.3	-0.4	0.3
Wheeze or whistling in the chest in last year	0.1	0.2	0.9	0.7	-1.0	-0.0	0.4	0.1	0.4	0.1	-0.6	0.2	0.0	0.1	0.8	0.4
Medication: Blood pressure	0.1	0.2	0.9	1.0	-0.2	0.0	0.1	0.9	0.4	-0.1	-0.3	-0.3	0.6	0.2	0.6	-0.0
Medication: Aspirin	0.1	0.1	0.4	-0.2	0.2	-0.4	-0.3	0.4	-0.3	-0.3	-0.5	0.7	0.0	-0.1	-0.1	0.0
Illnesses of siblings: Diabetes	0.1	0.2	0.6	0.3	-0.7	-0.0	0.2	-0.3	-0.2	0.3	0.5	0.5	-0.8	-0.1	0.3	0.3
Average weekly red wine intake	0.1	0.1	0.9	0.0	0.5	0.3	-0.0	0.6	-0.1	0.2	0.2	-0.1	0.9	-0.0	-0.0	-0.0
Mood swings	0.1	0.2	1.5	-0.2	-0.3	-0.0	-0.1	0.1	0.0	-0.4	-1.2	-0.0	-1.0	-0.3	0.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.1	0.4	-0.3	0.0	0.0	-0.3	0.2	0.6	0.3	-0.2	0.1	0.1	0.1
Asthma (self-reported)	0.1	0.2	1.0	-0.8	-1.0	0.2	-0.1	-0.0	-0.1	0.0	0.2	0.0	-0.9	-0.3	-0.7	-0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.9	-0.6	0.1	-0.1	-0.1	-1.0	-0.2	-0.0	0.5	0.2	-0.5	0.1	-0.4	0.0
Medication: Lisinopril	0.1	0.2	0.6	0.2	0.7	-0.5	-0.5	0.2	-0.3	-0.4	-0.1	-0.0	0.8	-0.4	-0.2	-0.4
Medication: Atorvastatin	0.1	0.2	1.2	0.2	1.1	-0.3	-0.2	-0.3	-0.2	-0.2	0.1	-0.2	-0.9	0.3	-0.1	-0.2
Number of operations (self-reported)	0.1	0.1	0.5	0.4	0.2	-0.2	-0.1	-0.7	-0.1	0.0	0.4	-0.0	0.0	-0.2	0.0	-0.1
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.7	-0.3	0.2	0.4	-0.2	0.2	0.1	-0.1	-0.4	-0.5	-0.8	-0.3	-0.3	-0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.1	0.4	-0.5	-0.5	0.0	-0.3	-0.7	-0.5	-0.2	-0.4	0.0	-0.3	-0.2	-0.4	-0.2
Hair Pigment	0.0	1.4	2.2	1.1	-0.5	1.4	1.1	0.0	0.9	1.3	1.5	1.5	-1.1	1.5	1.0	1.3
Relative age of first facial hair	0.0	0.1	0.2	-0.2	-0.1	-0.2	-0.0	-0.4	-0.1	-0.3	-0.4	-0.0	0.4	0.1	0.0	-0.0
Qualifications: College or University degree	0.0	0.1	0.4	-0.6	-0.0	0.3	0.1	0.1	-0.1	0.3	0.6	-0.1	0.2	0.2	-0.5	0.0
Back pain experienced in last month	0.0	0.1	0.3	-0.2	0.4	-0.1	0.1	-0.5	0.2	0.1	0.4	0.4	-0.2	0.1	-0.0	0.2
Medication: Blood pressure	0.0	0.0	0.1	0.3	-0.3	-0.2	0.0	-0.3	-0.0	0.1	0.1	0.1	0.0	0.1	0.2	0.1

Hub : Genes

BMS1P5

Models

Trait associations