Hub : Genes

BOC

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3640	0.0490	5.6e-17	0.134	0.169	0.227	0.207	0.223	4.9e-16	4.0e-20	3.1e-27	1.1e-24	1.0e-26
2	GTEx	Adipose Visceral Omentum	0.1660	0.0670	3.1e-03	0.029	NA	0.033	NA	0.041	1.1e-02	NA	7.5e-03	NA	3.4e-03
3	GTEx	Artery Aorta	0.2190	0.0610	1.3e-05	0.147	NA	0.130	NA	0.137	1.8e-08	NA	1.2e-07	NA	5.5e-08
4	GTEx	Brain Cerebellar Hemisphere	0.4740	0.1160	7.6e-04	0.098	NA	0.142	NA	0.195	1.7e-03	NA	1.7e-04	NA	9.8e-06
5	GTEx	Brain Cerebellum	0.4110	0.1280	2.9e-03	0.084	NA	0.220	NA	0.227	1.8e-03	NA	3.9e-07	NA	2.5e-07
6	GTEx	Pancreas	0.2600	0.0980	6.1e-03	0.127	NA	0.041	NA	0.102	5.1e-06	NA	7.6e-03	NA	4.5e-05
7	GTEx	Skin Not Sun Exposed Suprapubic	0.3140	0.0850	9.7e-05	0.119	NA	0.000	NA	0.081	4.5e-07	NA	3.1e-01	NA	3.4e-05
8	GTEx	Skin Sun Exposed Lower leg	0.1590	0.0530	1.1e-03	0.149	NA	0.129	NA	0.143	2.2e-12	NA	8.2e-11	NA	6.7e-12
9	TCGA	Brain Lower Grade Glioma	0.0469	0.0181	3.5e-05	0.053	0.052	0.056	NA	0.049	1.2e-06	1.4e-06	5.3e-07	NA	2.6e-06
10	TCGA	Thyroid Carcinoma	0.0870	0.0410	1.5e-03	0.050	0.022	0.027	NA	0.024	1.1e-05	3.1e-03	1.1e-03	NA	2.0e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	1.0	1.6	3.5	-1.9	-0.0	-0.9	-1.7	-1.6	-1.2	0.1	0.3	-1.9	1.3
Bipolar Disorder or Schizophrenia	0.3	0.6	4.2	-0.3	-0.1	-1.3	0.0	0.3	-2.0	-0.1	-0.3	-0.5	-0.3
Depressed Affect (Nagel 2018)	0.1	0.3	0.9	1.0	0.1	-0.8	0.2	0.1	-0.2	0.6	0.3	0.3	-0.6
Depression (Nagel 2018)	0.7	1.0	4.1	0.3	0.5	0.1	0.1	-1.0	-1.0	2.0	1.8	0.6	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.9	0.5	-0.2	1.3	1.2	0.9	0.0	-1.3	-0.9	0.2	-1.4
Neuroticism (Nagel 2018)	0.3	0.7	2.4	0.9	-1.6	-0.2	1.4	1.0	0.1	0.3	0.5	-0.8	-0.1
Schizophrenia (2018)	0.6	1.2	2.8	1.2	-0.2	-0.9	1.4	1.7	-1.4	-0.2	-0.6	0.9	-1.5
Schizophrenia vs Biploar Disorder	0.9	1.2	4.2	1.9	-0.4	-0.6	1.5	2.0	0.3	-0.6	-0.8	0.3	-0.7
Worry (Nagel 2018)	1.0	2.1	10.7	1.0	-3.3	-0.4	1.7	1.8	0.6	-0.7	0.0	-1.4	-0.2
Alzheimer’s Disease (in mother)	0.8	1.0	2.7	1.4	-0.8	-1.6	0.8	1.0	0.9	1.0	0.9	-0.3	-0.2
Alzheimer’s Disease (in father)	0.4	0.4	1.6	-0.3	-0.0	-1.0	1.0	0.5	-0.6	-0.2	-0.5	0.0	-1.3
Alzheimer’s Disease (including proxy)	0.4	0.7	2.4	0.1	-0.1	-1.5	0.1	-0.2	0.5	1.4	1.3	-0.1	-0.5
Crohns Disease (2017)	0.4	1.0	5.4	-0.3	-0.0	-2.3	0.8	1.3	0.5	-0.6	-0.8	-0.6	-0.5
Irritable Bowel Disease (IBD)	0.3	0.7	2.6	-0.7	-0.1	-1.6	-0.3	0.3	-0.0	-1.0	-1.1	-0.6	-1.2
Ulcerative Colitis (UC)	0.4	0.8	2.8	-0.9	0.0	-0.3	-1.3	-0.9	-0.2	-1.0	-1.1	-0.1	-1.7
Major Depression (MDD)	0.6	0.7	2.8	-1.7	-0.8	0.5	0.6	-0.3	0.8	0.6	1.1	-0.9	-0.2
Reaction Time	0.5	0.9	5.5	-0.8	-0.3	-0.4	-2.3	-1.2	0.6	0.2	-0.1	0.8	0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.6	1.3	-0.8	-0.6	0.8	0.7	-1.2	-0.1	-0.4	-0.1	-0.6
Breast Cancer	0.8	2.0	8.2	-0.7	2.7	1.1	-0.7	-0.6	-1.0	0.3	-0.3	2.9	-0.9
Ovarian Cancer	0.6	0.7	2.7	-1.6	0.6	0.1	0.0	-0.6	-1.3	-0.0	-0.2	0.6	-1.3
Prostate Cancer	1.1	1.6	4.1	1.9	-1.1	-0.6	0.9	1.7	0.4	-1.3	-0.7	-2.0	0.6
Age at First Birth	0.4	0.6	2.4	-1.0	0.5	0.9	0.6	0.2	-1.5	0.3	0.4	-0.3	-0.9
Bipolar Disorder (2011)	0.9	0.9	3.8	-2.0	0.0	0.9	-1.5	0.0	-0.6	-0.9	-0.8	-0.4	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.0	1.0	0.5	-0.5	-0.7	-0.2	-0.3	0.7	0.3	0.6	-0.0
Coronary Artery Disease (CAD)	0.4	0.5	1.6	0.6	-0.7	0.3	-0.3	0.7	1.3	-0.5	-0.3	-0.6	0.8
Crohns Disease (2012)	0.8	1.3	4.5	-0.3	-0.9	-2.1	-0.0	1.0	-1.0	-1.4	-1.2	-1.4	-0.4
Mean Putamen Volume	1.3	1.5	2.7	-1.6	1.6	0.1	-1.2	-1.6	1.3	1.0	1.0	1.3	0.4
Fasting Glucose	1.6	1.9	6.8	-2.2	0.5	0.6	-2.1	-2.6	-0.9	0.7	0.6	1.0	-0.3
HbA1C	0.3	0.3	1.1	1.1	-0.2	-0.0	-0.2	0.4	-0.4	-0.8	-1.0	0.1	-0.1
HDL Cholesterol	0.4	0.6	3.2	-1.8	0.4	0.4	-0.4	-1.0	-0.9	0.5	0.2	0.8	-0.2
LDL Cholesterol	1.2	1.9	7.1	-0.5	-0.2	0.3	-0.7	-0.2	1.5	-2.0	-2.2	-0.7	-2.7
Lupus	0.8	1.2	5.2	0.3	0.1	1.0	-0.0	-0.4	-0.4	2.0	2.3	0.9	0.7
Neuroticism (2016)	1.3	1.8	5.4	1.3	-0.3	-0.3	2.3	1.5	0.0	1.9	2.0	-0.3	1.2
Primary Biliary Cirrhosis	1.4	2.0	4.3	-2.1	-0.1	-0.3	-1.2	-2.0	-0.2	1.6	1.9	-0.6	1.8
Rheumatoid Arthritis	0.1	0.2	0.5	0.1	-0.3	-0.6	-0.7	-0.5	-0.5	0.2	0.3	0.2	0.4
Schizophrenia (2014)	0.6	1.2	4.6	0.7	0.5	-1.5	1.1	1.1	-2.1	0.0	-0.5	0.4	-1.4
Triglycerides	0.1	0.2	0.6	0.8	0.8	-0.4	-0.1	0.4	-0.1	-0.1	-0.2	0.3	-0.5
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.7	0.3	0.9	0.1	-1.2	-1.3	-0.8	-0.2	-0.7	0.9	-0.9
Ulcerative Colitis	0.9	1.3	3.0	-1.1	-0.8	-0.4	-0.9	-0.2	-0.7	-1.7	-1.5	-1.5	-1.4
Blood Eosinophil Count	0.2	1.3	3.5	1.9	-0.4	-1.0	0.8	1.8	-1.4	-0.7	-0.4	-1.2	-0.8
Blood Platelet Count	0.2	2.0	7.6	0.4	-1.9	-1.0	-0.0	-0.0	-2.2	-1.1	-1.1	-0.4	-2.8
Blood Red Count	0.7	6.5	18.6	-2.9	2.2	2.2	-4.3	-4.3	-1.1	-0.5	-1.0	2.5	-1.2
Blood White Count	0.1	0.8	2.5	-0.0	-0.6	0.7	-1.6	-1.6	-0.8	0.7	0.6	0.3	0.7
Heel T-Score	0.5	4.2	20.7	0.2	0.6	2.1	-1.9	-1.5	-1.1	-0.8	-2.0	4.5	-2.2
BMI	0.3	1.5	6.1	0.3	2.5	0.1	-0.5	-0.6	-1.0	0.9	0.1	2.4	-0.8
Height	1.2	22.5	52.7	-4.8	-5.2	7.3	-3.3	-5.9	4.3	-3.5	0.5	-6.8	-0.6
Waist Hip Ratio (WHR)	0.6	2.7	12.2	-1.3	-0.8	3.5	-2.0	-2.6	0.3	0.3	1.0	0.2	-1.0
Systolic Blood Pressure	0.3	1.3	5.9	0.4	-0.6	-0.6	0.4	-0.1	0.5	2.4	2.3	0.4	0.8
Smoking Status	0.3	0.7	4.2	-2.0	0.6	0.6	0.7	0.6	-0.6	0.4	0.6	-0.3	-0.8
Allergy or Eczema	0.3	0.8	2.8	1.7	-0.4	-0.0	1.3	1.2	-0.5	0.4	0.8	-0.5	0.4
Cardiovascular Disease	0.5	1.5	5.6	0.4	0.9	0.3	0.7	-0.1	-0.3	2.4	1.8	2.2	0.5
Hypothyroidism (self reported)	0.6	1.3	3.8	1.9	0.5	-0.7	1.2	1.0	-1.2	0.8	0.2	1.9	-0.3
Respiratory disease	1.3	3.0	12.5	0.9	-1.9	-3.5	1.7	2.0	0.4	0.6	0.5	-2.0	1.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	8.4	0.0	2.9	1.1	-0.4	-0.6	0.6	0.4	-0.0	2.0	-0.4
Lung FEV1/FVC ratio	0.9	4.7	16.6	-1.1	4.0	0.9	-0.3	-1.5	0.1	2.1	0.8	4.1	-2.3
Lung FVC	0.2	0.9	2.8	0.2	1.3	-1.4	-0.8	-0.1	0.0	1.1	0.4	1.7	-0.3
Neuroticism	0.8	1.8	7.2	1.0	-2.7	-0.9	1.5	1.0	0.0	1.1	1.4	-1.4	1.0
Chronotype (morning person)	0.7	1.7	11.4	0.9	1.7	0.4	-0.6	0.4	-0.7	0.4	-0.3	3.4	0.6
Hair Pigment	0.0	1.2	5.5	-0.6	-0.5	-1.0	-1.3	-1.5	0.3	-0.2	-0.3	0.2	-2.4
Tanning	0.1	0.7	1.3	-1.1	-0.0	0.6	-1.1	-1.1	0.4	-0.9	-0.9	-0.4	-0.8
Hand grip strength (left)	0.6	1.6	4.3	-1.2	-1.0	0.1	0.5	-0.5	1.5	1.5	2.1	-1.7	1.1
Number of treatments/medications taken	0.1	0.1	0.4	0.2	-0.7	0.3	0.4	-0.1	0.2	0.3	0.3	0.1	0.0
Average weekly spirits intake	0.3	0.4	1.1	0.4	-0.3	-1.1	0.4	0.4	-0.9	0.6	0.3	-0.6	-0.7
Sensitivity / hurt feelings	0.4	0.7	2.3	0.4	-0.5	0.5	1.5	1.2	1.0	0.2	0.5	-1.2	-0.1
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.5	0.7	0.6	0.1	0.8	0.1	0.4	1.2	0.9	0.8	-0.6
Hearing difficulty/problems: Yes	0.5	0.8	2.2	-0.8	0.5	1.5	-0.8	-1.3	-0.4	0.8	1.1	-0.3	-0.4
Relative age of first facial hair	0.5	1.1	3.4	-0.2	-0.6	0.6	-1.2	-1.1	-0.7	-1.6	-1.9	0.9	0.2
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	9.6	1.2	2.0	1.6	-0.6	-1.3	0.8	0.3	-0.2	3.1	-0.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.6	-1.6	-0.6	0.5	-0.2	-0.6	-0.8	0.8	0.6	0.1	0.2
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	0.5	-0.3	0.2	0.7	0.5	-0.3	0.3	0.4	-0.6	1.1
Systolic blood pressure, automated reading	0.3	0.9	3.6	0.5	0.9	-0.8	0.1	-0.2	-0.2	1.9	1.4	1.4	-0.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	3.8	0.7	-0.6	2.0	0.1	0.7	0.2	-0.6	-0.5	-0.0	0.7
Angina	1.3	1.7	6.8	1.2	1.9	0.8	-0.1	-0.0	1.3	-0.2	-1.1	2.6	-1.4
Medication for hormone replacement therapy	0.3	0.4	1.2	-0.4	-0.4	-0.9	0.3	0.2	-1.0	-0.3	-0.3	-1.1	-0.5
Vitamin and mineral supplements	0.9	1.2	5.2	0.1	-1.2	-1.4	0.3	0.1	0.1	1.0	1.0	-1.1	2.3
Supplements: Zinc	0.8	0.9	3.0	0.0	-0.3	0.5	0.1	0.4	0.2	-1.6	-1.5	0.8	-1.7
Medication: Co-codamol	0.5	0.6	1.6	-0.2	-0.6	-0.6	-0.1	0.4	-0.7	-1.3	-1.1	-0.8	-1.0
Medication: Metformin	1.4	2.0	6.9	-0.3	2.6	1.5	-0.1	0.0	1.6	0.8	0.6	2.5	-1.1
Diabetes (father)	0.5	0.6	3.3	-1.0	1.8	0.4	0.1	0.0	0.4	0.7	0.4	1.1	-0.1
Diabetes (mother)	2.4	3.0	16.2	-0.4	4.0	-0.7	-0.6	-1.1	0.4	0.4	-0.8	3.1	-1.0
Severe depression (siblings)	1.4	1.5	4.3	-1.7	0.6	2.1	1.0	-0.3	0.9	1.3	1.8	0.5	0.5
Pack years adult smoking proportion	0.8	1.2	4.3	-0.7	-1.3	2.1	-1.0	-1.4	-0.5	-1.3	-0.4	-0.4	0.0
Impedance of leg (right)	0.2	1.2	5.0	0.1	-2.2	0.0	-0.2	-0.1	0.8	-0.6	-0.9	0.8	-2.1
Leg fat-free mass (left)	0.3	1.3	4.4	-1.4	0.6	2.1	-0.3	-1.5	0.6	-1.1	0.2	-1.4	0.8
Trunk fat percentage	0.4	1.6	6.2	0.0	2.4	0.4	0.1	-1.0	0.2	1.0	0.1	2.5	-1.3
Hand grip strength (right)	0.4	1.1	2.9	-1.1	-0.4	0.5	0.4	-0.4	1.7	1.2	1.4	-1.0	1.3
Townsend deprivation index at recruitment	1.4	1.9	10.3	-0.9	0.3	0.8	-0.6	-1.2	0.3	-1.6	-1.7	0.3	-3.2
Current tobacco smoking	0.7	1.1	2.2	-1.5	0.6	1.0	0.9	1.0	-1.0	-1.5	-1.0	-0.7	-1.1
Average weekly fortified wine intake	2.9	3.4	10.4	0.6	0.4	-2.2	1.8	1.1	0.6	3.2	2.9	-0.2	2.3
Maternal smoking around birth	0.7	1.0	2.1	0.2	-0.0	0.6	-0.7	-0.7	1.0	1.3	1.2	1.4	1.4
Fed-up feelings	0.7	1.2	4.3	2.1	0.3	-1.1	1.6	1.3	-0.3	0.3	-0.0	0.9	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.5	1.2	-0.8	-0.3	0.6	0.1	-0.5	0.9	1.0	-0.6	-0.2
Relative age voice broke	0.6	1.0	3.0	-0.2	-0.0	-0.3	-0.1	-0.3	-0.9	-1.1	-1.5	1.5	-1.7
Taking other prescription medications	0.3	0.5	1.9	-0.2	-0.6	1.4	0.5	0.1	0.6	-1.1	-0.6	-0.7	0.3
Age when periods started (menarche)	0.3	0.6	1.8	-0.5	-1.4	-0.5	0.3	-0.3	0.1	0.9	1.3	-0.9	0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.7	-1.2	-0.9	0.4	-0.4	-0.4	-0.0	-0.5	-0.1	-1.3	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	4.6	-0.7	1.0	1.2	-1.6	-1.6	-2.0	-0.6	-1.1	1.8	-2.1
Tinnitus: Yes, but not now, but have in the past	1.2	1.2	4.5	1.5	-0.2	-0.7	1.3	2.1	-1.8	-0.1	-0.2	0.3	0.6
Qualifications: CSEs or equivalent	0.4	0.5	2.5	-1.6	0.2	0.1	-0.5	-1.0	-0.4	0.6	0.9	-0.1	-0.5
Serious illness, injury or assault to yourself	0.6	0.7	2.0	-0.8	1.4	0.5	-0.8	-1.3	0.2	0.3	0.1	0.7	1.2
High blood pressure	0.3	0.7	3.2	0.8	-0.3	0.4	0.4	-0.1	0.4	1.8	1.2	1.1	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.2	1.1	-0.5	0.7	0.8	0.6	-1.0	0.1	0.7	-0.4	-0.0
Multivitamins +/- minerals	1.3	1.7	4.3	-1.4	1.5	1.7	-0.2	-0.0	0.1	-1.2	-1.3	1.5	-2.1
Stomach or abdominal pain in last month	0.5	0.6	1.6	-0.0	1.3	0.7	-0.4	-0.9	0.7	-0.8	-1.0	0.8	-0.7
Supplements: Glucosamine	1.1	1.4	4.5	-0.8	-0.4	1.5	-1.7	-2.1	-1.3	-0.1	-0.2	0.9	0.9
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.6	-0.0	0.1	-0.5	0.8	0.5	0.8	0.7	0.6	-0.9	1.3
Medication: Atenolol	1.2	1.5	5.4	-1.1	1.4	-0.5	-0.9	-0.2	1.9	1.0	-0.2	2.3	-0.9
Medication: Levothyroxine sodium	0.6	1.0	2.4	1.0	0.4	1.3	-0.7	-0.6	-0.4	-1.3	-1.5	1.5	-0.7
Sitting height	0.6	4.2	10.4	-3.2	-2.1	1.7	-0.2	-2.1	2.2	0.1	1.9	-3.2	0.8
Chronic bronchitis/emphysema (father)	1.9	2.2	5.5	2.3	-1.5	-0.3	2.1	2.1	1.3	-0.3	0.3	-1.5	1.2
High blood pressure (mother)	0.8	1.2	3.4	1.1	0.4	-0.7	0.7	1.1	1.4	1.1	0.6	0.9	1.9
Body mass index (BMI)	0.4	1.9	10.0	-0.0	3.2	0.1	-0.3	-0.8	-0.5	0.9	0.1	2.5	-1.0
Impedance of leg (left)	0.2	1.0	6.9	0.0	-2.6	-0.1	0.3	0.2	0.7	-0.2	-0.4	-0.2	-1.6
Leg predicted mass (left)	0.3	1.4	4.5	-1.5	0.6	2.1	-0.3	-1.5	0.6	-1.1	0.2	-1.6	0.9
Trunk fat mass	0.3	1.4	5.3	-0.5	2.3	1.1	-0.1	-1.4	0.4	0.6	0.3	1.8	-1.0
Waist circumference	0.4	1.4	3.9	-0.8	1.6	1.7	-1.1	-2.0	0.6	0.2	0.3	1.1	-1.1
Number of incorrect matches in round	0.3	0.6	2.0	-0.1	0.7	0.5	-0.3	-0.3	-0.3	1.0	1.3	-0.1	1.4
Past tobacco smoking	0.2	0.4	1.4	1.2	-0.3	0.1	-0.1	-0.1	-0.2	-0.8	-0.3	-0.4	1.1
Alcohol usually taken with meals	0.3	0.5	2.0	-0.2	0.5	0.7	-0.2	-1.4	0.2	0.5	0.5	0.7	1.0
Nervous feelings	0.6	1.1	5.2	0.9	-2.3	0.3	1.3	1.3	0.1	-0.4	0.3	-1.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.4	-0.7	-0.8	0.2	1.6	1.3	-0.3	-0.8	-0.3	-1.0	-1.1
Hearing difficulty/problems with background noise	0.4	0.7	1.8	-1.3	0.5	0.5	-0.2	-0.8	1.2	1.0	1.4	0.1	0.1
Hair/balding pattern: Pattern 2	0.4	0.6	1.1	-1.0	-0.9	1.0	-0.3	-0.9	1.1	-0.4	0.2	-0.7	-0.5
Had menopause	1.5	1.9	5.2	-2.3	-0.7	1.8	-1.1	-1.5	-0.0	0.5	1.2	-1.4	1.6
Had other major operations	0.5	0.6	1.9	-0.5	-1.4	0.1	-0.6	-0.5	1.3	-0.2	0.2	-1.1	-0.1
Forced vital capacity (FVC)	0.2	0.7	1.6	-1.3	-0.6	1.2	-0.8	-1.1	0.5	-0.1	0.7	-0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	4.2	-1.4	1.2	1.6	-1.7	-1.8	-0.5	-1.6	-2.0	2.1	-1.7
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.1	-1.1	0.4	0.3	1.1	0.4	-0.6	-0.4	-0.5	0.3	-1.4
Qualifications: None of the above	0.2	0.5	1.5	-1.2	-0.6	0.8	-0.8	-0.8	-1.0	-0.1	0.5	-0.5	-0.3
Financial difficulties in last 2 years	1.2	1.6	5.0	0.4	-0.1	2.2	-0.9	-1.4	-0.4	-2.2	-1.7	0.6	-0.6
Mouth/teeth dental problems	0.2	0.3	1.3	-0.5	-0.3	-0.2	-1.2	-0.7	-0.0	-0.0	-0.2	-0.5	-0.2
Heart attack	0.6	0.7	2.3	0.7	0.5	-0.5	1.5	1.5	0.1	0.4	-0.1	-0.1	1.3
Allergy	0.1	0.3	1.0	0.0	1.0	-0.1	-0.1	0.2	0.5	-0.2	-0.9	0.8	-0.4
Pain all over the body in last month	0.6	0.7	2.4	-1.6	0.3	1.5	0.1	-0.6	0.2	0.6	1.1	-0.2	0.2
Diabetes (self-reported)	1.2	1.8	4.5	-0.9	2.1	2.0	-0.8	-0.6	1.4	0.4	0.1	2.1	-1.0
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.5	0.7	1.2	0.0	0.7	0.1	-0.6	1.2	1.2	0.8	0.3
Medication: Ramipril	1.3	1.7	6.3	2.5	0.4	-1.2	1.9	1.7	1.0	1.1	0.4	0.5	0.2
Medication: Simvastatin	0.5	0.8	1.8	1.1	1.1	-0.8	0.8	0.8	-0.0	1.3	0.9	0.8	-0.0
Fluid intelligence score	0.2	0.4	1.6	1.3	-0.2	-0.0	-0.2	-0.3	-0.4	1.0	0.7	0.3	0.5
Illnesses of siblings	0.7	1.0	4.8	2.2	0.3	-0.4	1.7	1.0	-0.2	-0.1	-0.3	0.4	0.6
Neuroticism score	0.9	1.8	5.4	1.6	-1.8	-1.3	2.3	2.2	-0.3	-0.0	0.1	-0.7	-0.4
Weight	0.3	1.4	4.2	-1.6	1.4	1.9	-0.6	-2.1	0.8	-0.1	0.4	0.2	-0.6
Impedance of arm (right)	0.2	0.8	4.4	0.3	-2.1	0.8	0.1	0.2	0.7	-1.2	-1.0	0.2	-0.0
Arm fat percentage (right)	0.7	2.7	12.7	0.2	3.3	0.5	-0.2	-1.0	-0.5	1.1	0.1	3.6	-1.0
Trunk fat-free mass	0.4	2.4	8.2	-2.0	-0.6	2.9	-0.5	-1.9	0.7	-1.0	0.7	-2.3	0.6
Hip circumference	0.1	0.5	3.2	-0.6	1.8	0.5	0.2	-0.8	0.1	-0.2	-0.2	0.4	-0.7
Time employed in main current job	2.4	2.7	7.1	0.4	1.2	1.5	-0.8	-1.4	-0.1	2.6	2.3	2.7	1.2
Alcohol intake versus 10 years previously	2.4	3.6	11.0	3.3	-0.0	-0.7	1.7	2.8	2.4	-1.9	-1.8	-1.0	0.5
Father’s age at death	0.5	0.7	2.4	0.7	-1.3	-0.1	1.5	0.7	-0.3	0.7	0.8	-0.8	0.1
Worrier / anxious feelings	1.2	2.3	6.1	1.3	-2.4	0.2	2.5	2.4	1.6	-0.2	0.5	-1.0	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.1	1.4	-0.6	-0.2	0.8	-0.1	0.9	0.5	0.5	-0.7	0.6
Falls in the last year	0.6	0.8	2.2	0.1	-0.9	0.9	0.2	0.6	0.8	-1.5	-1.4	0.3	-1.2
Hair/balding pattern: Pattern 3	0.7	1.0	3.6	-0.9	1.5	0.0	0.2	-0.2	-0.1	1.9	1.5	1.0	-0.1
Number of live births	1.0	1.5	6.3	-1.7	0.2	2.5	-1.2	-1.7	-0.2	0.5	0.7	0.2	-0.5
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.2	-1.5	1.0	1.2	-0.7	-1.3	0.1	0.5	0.7	1.1	-1.0
Pulse rate	0.6	0.9	3.5	0.7	1.1	0.7	-0.6	-1.2	-1.9	-0.9	-0.7	0.7	-0.7
Happiness	0.7	0.8	3.5	-0.5	-0.5	-0.7	1.9	1.4	0.7	0.4	0.4	0.5	-0.8
Noisy workplace	1.1	1.4	3.9	1.3	-1.3	-0.6	1.0	1.6	0.6	-1.2	-1.0	-2.0	0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.5	0.3	-0.8	0.5	0.1	0.3	0.3	-1.7	-1.9	-0.1	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.8	1.3	0.1	-1.2	-0.6	-0.8	0.5	0.4	0.1	-0.1	0.7
Mouth/teeth dental problems: Dentures	0.6	1.0	2.6	0.8	-1.1	-0.0	1.6	1.5	-0.0	0.7	1.2	-1.2	0.7
Asthma	0.7	1.4	5.9	-0.1	-2.0	-2.4	0.4	0.5	0.3	0.7	0.5	-1.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.1	-0.3	-1.0	-0.3	-0.8	-0.5	1.2	-1.8	-1.4	-0.8	0.2
Medication: Cholesterol lowering	0.7	1.0	2.7	0.9	1.5	-0.9	0.9	0.7	-0.4	1.6	1.1	1.2	0.1
Depression (self-reported)	0.9	1.1	4.4	1.5	-0.7	-0.6	2.1	1.8	0.2	0.3	0.4	0.0	-0.2
Medication: Lansoprazole	0.7	0.8	1.8	-0.2	1.3	-0.9	-0.8	-0.9	-0.8	1.3	1.1	-0.2	0.2
Prospective memory result	0.5	0.6	2.2	1.1	0.2	-0.7	0.2	1.5	0.1	-0.9	-0.8	-0.3	-0.3
Lung cancer (father)	0.3	0.3	1.0	-0.1	-0.9	0.1	-0.9	-0.2	0.5	-0.5	-0.4	-1.0	-0.3
Illnesses of mother	0.4	0.6	2.5	-0.3	0.4	1.6	-0.1	-0.3	-0.2	-1.2	-0.8	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.4	-1.8	0.3	0.8	-1.2	-1.4	1.0	-0.1	0.0	0.7	-0.9
Pulse wave Arterial Stiffness index	1.3	1.5	5.7	-2.4	0.1	0.7	-1.1	-2.2	-1.1	0.8	0.8	-0.3	-0.4
Impedance of arm (left)	0.2	0.8	4.0	0.4	-2.0	0.3	0.1	0.3	0.9	-1.1	-1.1	0.0	-0.2
Arm fat mass (right)	0.5	2.0	8.7	-0.5	3.0	1.3	-0.4	-1.5	0.2	0.6	0.1	2.4	-1.0
Trunk predicted mass	0.4	2.4	8.0	-1.9	-0.6	2.8	-0.6	-2.0	0.7	-0.9	0.8	-2.3	0.7
Standing height	0.8	8.4	23.6	-3.5	-3.3	4.1	-0.5	-2.8	2.7	-1.9	0.8	-4.9	0.7
Length of working week for main job	0.5	0.6	1.7	-0.5	1.1	0.2	-0.7	-0.5	-0.2	-0.4	-1.0	1.3	-0.5
Exposure to tobacco smoke at home	0.2	0.2	0.7	0.1	-0.1	0.1	-0.3	0.2	0.9	-0.5	-0.4	-0.6	0.6
Breastfed as a baby	0.5	0.6	2.6	-1.0	-1.2	-0.4	-0.1	-0.3	0.4	0.2	0.3	-1.6	-0.8
Tense / ‘highly strung’	0.8	1.4	5.5	0.5	-2.3	-0.2	1.7	1.9	0.6	-0.4	0.1	-1.1	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.4	-1.4	-2.1	0.8	-0.7	-0.8	0.5	-1.2	-1.0	-0.4	-0.9
Hair/balding pattern: Pattern 4	0.8	1.9	6.0	1.9	2.4	-0.5	0.4	1.6	-0.8	-0.3	-0.9	2.2	0.1
Birth weight of first child	1.0	1.8	6.0	-0.5	-2.2	-0.2	0.3	-0.7	0.5	2.4	2.4	0.1	0.5
Peak expiratory flow (PEF)	0.8	1.8	4.4	-1.5	2.1	0.9	-0.2	-1.5	0.0	1.6	1.3	1.9	0.5
Pulse wave reflection index	0.2	0.3	1.0	-0.1	-0.3	0.2	0.2	-0.0	0.1	1.0	0.8	0.8	-0.0
Ever highly irritable/argumentative for 2 days	1.2	1.5	4.0	-1.2	-0.1	0.5	-0.8	-1.6	0.1	2.0	1.9	1.0	-0.9
Loud music exposure frequency	0.9	0.9	3.3	-0.2	1.6	1.3	-0.4	-1.8	0.5	0.4	0.8	0.8	-0.0
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.4	1.5	-0.8	-0.5	1.3	1.5	-0.4	-0.7	-0.8	-0.4	1.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	4.1	1.1	0.7	-0.5	0.4	0.3	-0.5	-0.2	-0.6	2.0	-1.0
Blood clot in the leg (DVT)	1.9	2.4	5.4	-1.2	1.1	2.3	-1.8	-2.0	2.1	-0.9	-0.6	1.6	-0.8
Medication: Paracetamol	0.5	0.8	2.5	0.6	0.6	0.8	-0.6	-0.7	0.9	-1.6	-1.6	0.4	-0.4
Headache pain in last month	0.7	1.3	4.8	0.4	-1.1	1.3	-0.3	-0.2	0.8	-2.2	-1.6	-0.7	-0.9
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	4.0	-1.9	-1.4	1.5	-1.6	-1.6	-0.1	-2.0	-1.1	-1.6	-1.1
Glaucoma (self-reported)	0.4	0.5	1.8	0.2	0.6	1.3	0.6	0.8	-0.2	0.3	0.5	1.2	0.1
Gout (self-reported)	1.0	1.4	5.4	-2.3	0.6	0.5	-1.0	-0.6	-1.8	-0.5	-0.8	0.7	-1.6
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.5	1.1	1.1	-0.2	0.2	-0.0	-0.9	0.9	0.2	2.1	0.1
Medication: Amlodipine	1.3	1.8	5.5	0.3	-0.6	0.1	0.5	-1.0	-0.7	2.2	2.3	-0.3	2.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.4	0.9	-1.8	-0.5	-0.0	0.4	0.4	-0.3	-0.2	-1.9	0.4
Birth weight	1.3	2.8	9.7	-0.2	-2.9	-1.6	0.5	0.8	-1.2	-1.8	-1.2	-3.1	0.6
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.6	-0.7	-0.9	0.2	-1.1	-0.5	-1.3	-1.2	-0.9	-1.0	-0.8
High blood pressure (siblings)	0.5	0.7	2.5	-1.6	-1.5	0.2	-0.6	-0.6	0.1	0.6	0.9	-0.6	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.1	3.8	-1.9	-0.9	0.6	-1.5	-1.3	1.2	-0.3	0.1	-0.5	-0.2
Body fat percentage	0.6	2.3	9.8	-0.0	2.9	0.5	-0.2	-1.1	-0.0	1.1	0.1	3.1	-1.6
Leg fat percentage (right)	0.8	2.7	12.8	-0.2	2.5	0.6	-0.7	-1.3	-0.1	1.2	0.1	3.6	-2.0
Arm fat-free mass (right)	0.3	1.4	4.4	-1.6	-0.1	1.7	-0.3	-1.5	1.0	-0.4	0.9	-2.1	0.4
Exposure to tobacco smoke outside home	0.7	1.0	2.1	-0.9	0.8	0.1	-1.4	-0.8	-0.7	-0.4	-0.9	1.4	-1.4
Comparative body size at age 10	0.4	1.2	4.1	0.2	1.4	-0.4	1.9	2.0	-0.9	-0.4	-1.0	0.6	-0.0
Number of full brothers	0.8	1.0	3.2	0.5	1.5	0.3	-0.9	0.1	-0.1	-1.4	-1.8	1.0	-0.3
Worry too long after embarrassment	0.1	0.2	0.8	-0.0	-0.8	-0.7	0.0	0.2	0.1	0.0	0.1	-0.9	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	5.1	0.1	-1.7	1.5	2.3	1.2	0.8	1.1	1.7	-0.6	1.3
Wheeze or whistling in the chest in last year	0.5	1.0	2.3	0.9	-0.5	-0.4	1.5	1.4	-0.8	0.4	0.7	-0.9	1.5
Number of children fathered	2.6	2.9	9.8	-0.3	2.7	0.3	-1.7	-1.3	-2.0	1.2	0.3	3.1	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.6	1.5	0.3	1.2	1.1	1.1	0.6	1.1	0.1	0.7	0.1	-0.6
Age at first live birth	0.3	0.5	1.1	1.1	-0.2	-0.7	1.1	0.4	-0.5	0.9	0.6	0.7	0.1
Pulse wave peak to peak time	1.0	1.2	3.2	1.8	-0.7	-0.2	1.0	1.8	1.5	-1.0	-0.7	-0.3	0.4
Health satisfaction	0.5	0.7	1.4	-0.3	-0.4	-0.8	0.9	-0.2	1.1	1.1	1.2	-1.1	-0.1
Shortness of breath walking on level ground	0.4	0.4	2.7	0.6	-0.3	-1.6	0.3	0.1	-0.9	0.1	-0.4	0.1	-0.3
Qualifications: College or University degree	0.3	1.0	2.1	-0.6	-1.3	-0.8	0.6	0.3	-1.4	-1.4	-1.4	0.0	-0.8
Eye problems/disorders: None of the above	0.4	0.5	1.9	1.4	-0.0	-0.1	0.9	1.0	-0.0	-0.6	-0.4	-0.9	-0.2
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.2	-0.8	0.4	1.8	0.8	0.4	0.6	-1.3	-0.7	-0.3	-0.6
Emphysema/chronic bronchitis	0.9	1.0	3.4	-0.4	-1.1	-0.9	0.6	0.1	0.7	1.5	1.9	-1.1	0.6
Medication for pain relief, constipation, heartburn	0.7	1.2	4.1	-0.9	-0.4	-1.0	0.0	-0.0	-1.1	1.8	2.0	-0.8	0.3
Neck or shoulder pain in last month	1.2	1.8	4.5	2.1	0.8	1.3	0.4	1.4	1.6	-1.7	-1.5	0.7	-0.4
Medication: Blood pressure	2.1	3.7	9.1	3.0	0.9	-2.2	2.5	2.9	0.7	2.0	0.9	1.3	1.1
Angina (self-reported)	1.4	1.9	7.7	0.9	2.1	0.6	0.0	0.1	1.4	-0.2	-1.1	2.8	-1.4
Migraine (self-reported)	0.5	0.6	3.0	-0.3	-0.1	0.7	0.4	0.5	-0.5	-1.7	-1.0	-0.7	0.3
Medication: Ibuprofen	0.8	1.0	2.4	-0.2	-1.5	0.7	-1.1	-1.1	0.7	-1.5	-1.0	-1.0	0.1
Medication: Allopurinol	0.5	0.6	2.2	-0.9	0.3	0.7	-0.8	-0.1	-1.5	-0.6	-0.8	0.9	-0.5
Medication: Omeprazole	0.3	0.4	1.6	0.3	-0.3	0.7	-0.5	-0.2	0.2	-1.0	-1.3	0.5	-0.1
Medication: Seretide 50 evohaler	0.7	0.8	3.3	0.3	-0.7	0.5	1.8	0.9	0.3	-0.6	-0.2	-1.1	-1.2
Mean time to correctly identify matches	1.0	2.0	9.1	-1.1	0.3	0.1	-3.0	-2.2	0.2	1.2	0.7	1.5	0.4
Heart disease (mother)	0.9	1.1	2.5	-1.0	-1.6	-0.7	-0.4	-1.2	0.2	1.2	1.3	-1.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.5	0.3	-0.5	1.8	-1.9	-1.0	0.2	-0.8	-0.5	-0.6	-0.5
Whole body fat mass	0.4	1.6	6.1	-0.6	2.5	1.4	-0.2	-1.4	0.4	0.5	0.1	1.9	-1.2
Leg fat mass (right)	0.5	1.8	6.1	-0.5	2.5	1.3	-0.2	-1.2	0.1	0.5	-0.1	2.5	-1.3
Arm predicted mass (right)	0.2	1.2	3.5	-1.4	-0.1	1.7	-0.3	-1.4	1.2	-0.6	0.6	-1.9	0.0
Pulse rate, automated reading	0.4	1.4	4.9	-0.3	-0.7	1.0	-1.9	-2.2	-1.3	-0.6	-0.1	-0.9	0.9
Alcohol intake frequency.	0.4	0.9	4.8	-0.5	1.0	2.2	-0.1	-0.2	1.2	-0.6	-0.2	0.7	-0.2
Comparative height size at age 10	0.6	3.2	11.5	-2.2	-1.4	2.5	-0.7	-1.7	1.2	-1.4	0.3	-3.4	0.2
Number of full sisters	2.0	2.4	6.1	-2.5	-0.1	1.0	-1.1	-2.4	2.5	0.8	1.2	-1.5	-0.1
Suffer from ‘nerves’	2.6	4.1	10.0	2.5	-3.2	-2.2	2.6	2.8	-0.2	-1.1	-1.0	-1.5	-0.6
Overall health rating	0.1	0.3	0.9	-0.0	0.6	0.1	-0.6	-0.9	0.7	0.6	0.5	0.3	0.4
Chest pain or discomfort	0.3	0.4	2.0	-0.1	0.9	1.4	0.1	-0.7	0.5	0.3	0.4	0.6	-0.1
Had major operations	0.5	0.6	2.9	-1.2	0.6	0.3	0.9	0.2	1.7	0.5	0.3	0.4	0.4
Age at last live birth	0.6	0.9	2.4	-0.5	-1.5	-0.9	0.4	-0.4	-0.8	1.1	1.4	-1.0	0.0
Family relationship satisfaction	0.4	0.5	1.6	-0.2	-1.3	-0.7	0.9	1.1	-0.4	-0.0	-0.0	-1.0	0.1
Leg pain on walking	0.7	0.8	3.5	-1.2	-1.0	0.4	-0.2	-0.6	0.9	-0.8	-0.1	-1.9	-0.5
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	6.3	0.1	2.5	-0.1	-0.0	-0.3	0.3	1.5	0.9	1.5	1.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.5	-1.0	0.0	1.2	-0.5	-0.1	1.0	-0.6	-0.3	-0.2	1.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	-0.2	-0.9	0.2	0.0	0.7	-0.6	0.1	0.2	-1.0	-0.4
Medication: Aspirin	0.6	0.9	2.6	0.7	0.9	-0.9	1.0	1.5	0.4	0.2	-0.6	1.6	-0.0
Supplements: Vitamin C	1.2	1.4	4.8	-1.4	-0.6	-0.6	-2.2	-2.0	0.5	0.6	0.5	-0.4	-1.1
Knee pain experienced in last month	1.7	2.7	7.2	-1.9	1.2	2.7	-1.7	-2.5	1.9	0.6	0.9	1.0	-0.1
Hypertension (Self-reported)	0.3	0.9	3.0	1.3	0.0	0.4	0.8	0.3	0.3	1.7	1.2	1.3	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.8	2.7	0.7	1.4	1.1	-0.5	-0.1	0.0	0.8	0.7	1.6	0.4
Illnesses of father: Heart disease	0.3	0.4	0.8	-0.3	-0.8	-0.7	-0.4	-0.4	0.5	-0.7	-0.7	-0.9	0.5
Illnesses of siblings: Diabetes	0.3	0.3	0.7	-0.7	0.2	0.6	-0.7	-0.1	0.8	-0.5	-0.5	0.8	0.4
Smoking status: Previous	0.2	0.4	1.3	-0.3	0.1	-0.6	0.5	0.4	0.8	1.1	0.8	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.3	-1.8	0.3	1.8	-0.6	-1.1	0.7	-1.8	-0.8	-0.3	-1.8
Whole body fat-free mass	0.3	1.9	6.1	-1.6	-0.2	2.5	-0.3	-1.6	0.8	-1.0	0.6	-2.2	0.8
Leg fat-free mass (right)	0.3	1.5	4.8	-1.4	0.3	1.9	-0.0	-1.2	0.5	-1.1	0.3	-2.2	1.0
Arm fat percentage (left)	0.7	2.7	11.8	0.3	3.3	0.4	-0.4	-1.0	-0.6	1.0	-0.1	3.4	-1.2
Average weekly red wine intake	0.5	0.8	3.5	-0.5	-1.2	1.9	0.5	-0.0	-1.2	-0.0	0.4	-0.6	0.2
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.4	-1.6	0.5	-1.4	-0.4	0.0	-0.6	0.9	0.2	1.0	-1.2
Mood swings	0.7	1.3	3.4	1.6	-0.4	-1.8	1.3	1.7	-0.1	-0.2	-0.8	-0.2	-1.0
Loneliness, isolation	0.7	1.0	2.2	1.2	0.7	0.4	0.4	0.5	0.8	-1.0	-1.3	1.3	-1.5
Long-standing illness, disability or infirmity	0.3	0.4	1.1	1.0	0.6	0.7	0.1	-0.6	0.7	0.6	0.4	1.0	0.2
Ever had bowel cancer screening	2.0	2.3	5.7	-2.0	1.2	0.0	-1.3	-2.2	-0.6	2.4	2.1	1.0	-0.4
Diabetes diagnosed by doctor	1.6	2.6	10.2	-0.3	3.2	2.1	-0.5	-0.6	1.8	0.4	-0.1	2.6	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.2	-1.5	0.4	0.5	-1.0	-1.3	-0.3	0.3	0.3	0.8	-0.3
Friendships satisfaction	0.9	1.1	2.9	-0.5	-0.8	-0.8	1.6	1.2	1.7	1.0	1.0	-0.6	0.1
Qualifications: nursing, teaching	0.5	0.8	2.1	0.6	0.2	0.9	1.3	1.4	-0.2	-1.0	-1.0	0.8	0.4
Commuting to job workplace: Walk	1.1	1.2	3.0	-1.7	0.9	0.8	-0.7	-0.7	-0.8	-0.2	-0.4	1.7	-1.6
Eye problems/disorders: Cataract	0.5	0.6	2.0	-1.4	-0.3	-0.4	-0.5	-0.8	-1.4	-0.5	-0.8	-0.1	0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.6	0.0	1.6	0.0	-1.4	-1.4	0.5	0.8	0.4	1.5	1.3
Medication for cholesterol	0.4	0.7	2.0	-0.2	1.4	0.2	-0.9	-0.4	1.0	-1.0	-1.1	0.4	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	8.4	-1.5	-0.2	2.9	-2.1	-1.8	0.7	-1.9	-1.8	0.3	-1.4
Back pain experienced in last month	0.2	0.3	1.0	-0.6	-0.3	-0.7	-0.1	-1.0	0.9	0.2	0.3	-0.0	0.5
Mineral and other dietary supplements	0.4	0.6	2.9	0.1	-0.6	0.2	0.4	0.8	1.7	-0.1	0.2	-0.9	0.9
Breast cancer (self-reported)	1.2	1.4	3.9	-0.8	-0.7	1.4	-0.4	-0.2	-0.8	-2.0	-1.6	0.4	-1.8
Asthma (self-reported)	0.9	1.7	6.0	0.4	-2.1	-2.5	0.9	1.0	0.1	0.9	0.7	-1.7	1.0
Osteoporosis (self-reported)	1.1	1.4	4.9	0.4	-2.2	0.4	0.5	0.8	-1.4	-0.7	-0.0	-2.0	1.0
Osteoarthritis (self-reported)	1.1	1.5	4.0	-0.6	1.2	1.3	-1.1	-2.0	0.6	1.1	0.7	1.8	0.9
Medication: Aspirin	0.6	0.8	2.2	0.7	0.9	-0.7	1.2	1.4	0.1	0.3	-0.4	1.5	-0.3
Medication: Gliclazide	1.1	1.2	4.0	-0.6	0.8	1.8	-0.5	-0.4	0.4	-1.1	-0.8	1.2	-2.0
Illnesses of father: None of the above (group 1)	0.7	0.9	2.4	-1.0	0.4	1.5	-1.5	-1.4	0.2	-0.7	-0.5	-0.2	-0.5
Smoking status: Current	0.7	1.2	2.8	-1.7	0.7	0.8	0.6	0.6	-1.0	-1.4	-1.1	-0.4	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.4	8.6	0.4	1.9	0.4	-0.4	0.0	0.4	0.7	-0.1	2.9	-0.5
Whole body water mass	0.3	1.9	5.9	-1.7	-0.2	2.4	-0.3	-1.7	0.8	-0.8	0.7	-2.1	0.8
Leg predicted mass (right)	0.3	1.6	4.8	-1.5	0.3	2.0	-0.1	-1.3	0.7	-1.2	0.3	-2.2	1.0
Arm fat mass (left)	0.4	1.8	7.3	-0.4	2.7	1.3	-0.6	-1.5	0.0	0.5	0.0	2.3	-1.0
Number of self-reported non-cancer illnesses	0.9	1.5	3.2	1.4	1.5	0.1	1.2	0.3	0.7	1.8	1.5	1.2	1.3
Average weekly champagne plus white wine intake	0.3	0.5	2.7	0.2	-0.1	-0.1	1.6	0.4	1.1	0.5	0.1	-0.6	-0.1
Miserableness	0.5	0.8	1.9	1.4	1.0	-0.7	0.9	0.6	-0.3	1.2	0.6	1.3	0.1
Guilty feelings	0.3	0.5	1.2	-0.8	-0.9	0.2	0.6	-0.0	0.0	0.8	1.1	-0.9	0.6
Wears glasses or contact lenses	0.2	0.3	1.4	-0.5	1.2	0.2	-0.2	-0.3	-0.4	0.3	-0.1	0.3	-0.7
Ever taken oral contraceptive pill	0.8	0.9	3.1	-0.7	0.3	-0.3	-1.4	-1.2	0.8	1.0	0.4	1.8	0.3
Hearing aid user	0.6	0.6	1.8	-0.9	-0.5	-0.1	1.2	1.0	-1.3	0.3	0.7	-0.7	-0.2
Mother’s age at death	0.4	0.5	2.3	0.1	-0.4	0.9	0.7	1.0	1.5	-0.5	-0.3	-0.3	0.6
Financial situation satisfaction	1.9	2.3	6.2	-1.3	1.7	1.3	-1.2	-1.1	1.9	0.1	-0.3	2.5	-2.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.7	-0.2	0.1	-0.9	0.8	0.8	-0.3	-0.1	0.0	-1.3	1.1
Commuting to job workplace: Public transport	0.2	0.3	0.8	-0.4	0.1	-0.5	0.6	0.4	-0.1	-0.5	-0.7	0.9	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	1.8	-0.3	1.1	0.8	0.3	-0.1	0.1	1.2	1.3	0.8	0.7
Medication: Blood pressure	0.5	0.9	2.7	0.7	-1.3	0.5	0.4	-0.2	0.3	1.6	1.6	0.3	0.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	5.1	-0.0	0.6	2.3	-0.1	-0.5	1.0	0.6	0.8	1.3	0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	3.1	0.1	0.5	-0.5	-0.4	-0.4	-0.1	-0.0	-0.3	-0.1	-1.8
High cholesterol (Self-reported)	0.1	0.2	0.9	0.2	0.4	-0.1	-0.2	-0.2	-0.5	0.4	0.2	1.0	-0.6
Medication: Bendroflumethiazide	0.7	1.0	2.5	0.9	-1.1	-0.6	0.7	0.1	-0.7	1.3	1.6	-0.7	1.5
Medication: Paracetamol	0.4	0.6	1.6	0.5	0.8	1.0	0.6	-0.0	0.5	-1.1	-1.3	0.8	-0.5
Medication: Lisinopril	1.0	1.2	3.6	1.8	-0.5	-0.3	0.4	0.5	1.9	0.9	1.1	-0.1	1.7
Medication: Atorvastatin	1.2	1.5	3.2	-0.2	1.0	1.7	-0.8	-0.5	1.2	-1.7	-1.8	1.4	-0.9
Illnesses of father: High blood pressure	1.3	1.7	5.6	2.4	-0.5	-1.0	1.9	1.8	-1.2	-0.3	-0.3	-0.5	1.0
Alcohol drinker status: Never	0.3	0.3	2.6	0.0	-0.2	1.6	-0.4	-0.6	-0.2	-0.3	0.2	0.1	0.3
Ever smoked	0.3	0.6	2.9	-1.7	0.5	-0.2	0.3	0.4	-0.8	1.0	0.6	0.4	-0.8
Basal metabolic rate	0.3	1.6	6.0	-1.8	0.3	2.5	-0.4	-1.8	0.8	-0.8	0.6	-1.5	0.3
Leg fat percentage (left)	0.6	2.2	8.8	-0.2	2.5	0.5	-0.4	-1.2	-0.4	1.5	0.5	3.0	-1.5
Arm fat-free mass (left)	0.3	1.5	5.2	-1.7	0.0	2.3	-0.4	-1.8	0.9	-0.3	0.9	-1.6	-0.2
Number of operations (self-reported)	1.3	1.9	6.2	-2.1	0.0	2.5	-0.1	-1.1	2.0	0.7	1.1	0.3	-1.0
Average weekly beer plus cider intake	1.0	1.5	3.5	-1.9	-0.9	1.2	-1.0	-1.9	0.4	0.6	1.0	-0.5	-1.7
Irritability	1.5	2.5	8.2	2.0	0.5	-1.4	2.6	2.9	-0.8	0.8	0.2	1.5	-0.4
Risk taking	0.4	0.6	1.4	-0.5	0.1	0.0	1.1	-0.3	0.6	1.2	0.9	1.2	-0.5
Ever had prostate specific antigen (PSA) test	1.1	1.3	3.1	0.9	0.6	-0.5	1.1	0.7	-0.9	1.8	1.5	0.6	1.7
Fractured/broken bones in last 5 years	1.6	2.1	8.4	1.0	-0.3	0.8	0.2	1.4	-0.3	-2.9	-2.0	-2.1	-0.4
Age started oral contraceptive pill	0.4	0.5	1.7	0.6	-1.2	0.1	-0.8	-0.1	1.3	-0.7	-0.5	-0.1	-0.1
Diastolic blood pressure, automated reading	0.3	0.8	2.5	1.0	0.7	0.2	0.1	0.2	-1.4	-0.7	-0.9	0.9	-1.6
Ever depressed for a whole week	0.5	0.7	1.7	-0.7	-0.8	-0.5	1.1	0.6	1.2	-0.1	-0.5	0.5	-1.3
Unable to work because of sickness or disability	0.2	0.3	1.0	1.0	0.2	0.4	0.3	-0.1	0.4	0.7	1.0	0.3	0.2
Commuting to job workplace: Cycle	1.2	1.5	5.0	-1.3	-0.3	-0.2	-2.2	-1.9	-1.1	-0.4	-0.7	0.4	-1.4
Myopia	0.4	0.6	2.1	0.4	-1.4	0.7	0.0	0.1	-0.6	-1.1	-0.8	-0.6	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.5	-1.1	0.1	-0.0	-0.1	0.0	-0.0	-1.2	-0.5	-1.2	0.1
Cholesterol lowering medication	0.6	0.9	3.5	0.0	-0.3	1.6	0.5	0.1	0.5	-1.1	-0.8	0.1	-1.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.2	-0.1	0.1	0.4	-1.1	-0.7	-0.2	-0.5	-0.7	0.7	0.3
Pain experienced in last month	1.1	1.8	7.9	0.6	0.2	-2.8	0.2	1.2	-2.7	1.1	0.3	0.1	0.2
Supplements: Calcium	0.5	0.5	1.4	0.3	-0.5	0.7	-0.7	-0.4	-0.2	-1.1	-1.2	0.8	-0.4
Basal cell carcinoma (self-reported)	0.7	0.9	2.1	-0.5	-0.8	-1.1	1.2	0.8	-1.3	0.4	0.7	-1.4	0.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.9	1.1	0.5	-0.5	1.7	1.7	0.2	0.3	-0.2	-0.0	1.0
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	5.0	-0.9	1.3	2.2	-1.5	-1.7	2.0	-0.9	-0.6	1.6	-0.6
Heart disease (siblings)	0.5	0.6	2.3	-0.5	1.1	0.0	-1.5	-0.9	-0.1	-0.0	-0.3	0.7	-1.0
Alcohol drinker status: Previous	1.5	1.8	5.9	-2.2	1.1	2.4	-0.7	-1.4	-0.5	0.0	0.1	1.2	-1.1
Pack years of smoking	1.0	1.4	6.0	-0.9	-1.1	2.4	-1.2	-1.6	-0.0	-1.2	-0.3	-0.2	0.4
Impedance of whole body	0.2	0.9	5.8	0.2	-2.4	-0.1	0.2	0.2	0.8	-0.8	-0.9	-0.2	-1.0
Leg fat mass (left)	0.4	1.6	5.9	-0.5	2.4	1.4	-0.2	-1.3	-0.1	0.6	0.2	2.1	-1.2
Arm predicted mass (left)	0.3	1.7	6.5	-1.7	-0.1	2.5	-0.4	-1.9	0.8	-0.6	0.7	-1.4	0.0