Hub : Genes

BST1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 METSIM Adipose 0.0350 0.0151 5.5e-03 -0.001 0.011 -0.001 0.010 0.000 4.3e-01 8.4e-03 5.8e-01 1.1e-02 3.3e-01
2 NTR Blood 0.1336 0.0220 0.0e+00 0.057 0.100 0.115 0.107 0.117 9.0e-18 1.7e-30 5.1e-35 1.4e-32 1.1e-35
3 ROSMAP Brain Pre-frontal Cortex 0.0648 0.0216 2.2e-04 0.025 0.013 0.017 0.016 0.019 3.1e-04 7.1e-03 2.3e-03 3.0e-03 1.5e-03
4 YFS Blood 0.2384 0.0281 0.0e+00 0.302 0.335 0.367 0.357 0.367 7.2e-101 3.0e-114 2.1e-127 2.1e-123 1.1e-127
5 TCGA Bladder Urothelial Carcinoma 0.0920 0.0370 3.6e-04 0.022 0.037 0.047 NA 0.044 4.9e-03 4.1e-04 7.8e-05 NA 1.3e-04
6 TCGA Breast Invasive Carcinoma 0.0282 0.0139 2.5e-03 -0.001 0.008 0.000 NA -0.001 5.1e-01 5.9e-03 3.0e-01 NA 5.9e-01
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0375 0.0188 2.1e-03 0.016 0.019 0.007 NA 0.014 5.6e-03 2.9e-03 5.4e-02 NA 9.0e-03
8 TCGA Prostate Adenocarcinoma 0.0912 0.0341 4.9e-05 0.024 0.048 0.046 NA 0.041 1.5e-03 8.3e-06 1.3e-05 NA 3.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.4 0.9 0.4 -0.4 0.9 -0.8 -0.6 0.3 0.7 -0.1
Bipolar Disorder or Schizophrenia 0.5 1.1 2.3 1.3 -1.0 1.5 -1.3 0.8 -0.2 -0.0 1.3
Depressed Affect (Nagel 2018) 0.9 2.0 7.9 -1.4 0.2 1.6 -1.0 1.0 -0.7 2.8 1.0
Depression (Nagel 2018) 1.5 2.2 4.2 -1.8 -0.7 1.8 -2.0 0.4 -1.7 1.5 1.1
Intelligence (Savage-Jansen 2018) 0.4 1.4 2.8 0.9 0.8 -1.7 1.2 -1.5 -0.1 -0.6 -1.6
Neuroticism (Nagel 2018) 1.6 3.9 12.4 -1.6 -0.0 2.6 -1.7 1.6 -0.9 3.5 1.8
Schizophrenia (2018) 0.7 1.5 3.0 1.3 -1.1 1.2 -1.1 1.5 -0.6 -0.8 1.7
Schizophrenia vs Biploar Disorder 1.1 1.4 3.2 1.0 1.3 0.5 1.1 1.7 0.7 0.6 1.8
Worry (Nagel 2018) 1.4 3.0 6.3 0.7 0.3 2.5 -0.9 2.5 -0.3 1.9 2.4
Alzheimer’s Disease (in mother) 1.3 1.5 4.3 -0.2 0.3 1.9 -0.6 1.3 0.6 2.1 1.3
Alzheimer’s Disease (in father) 0.3 0.4 1.7 1.3 -0.6 -0.2 0.1 0.1 0.7 -0.4 0.4
Alzheimer’s Disease (including proxy) 0.3 0.5 1.5 -0.0 0.9 0.3 0.6 0.3 0.8 1.2 0.4
Crohns Disease (2017) 0.4 0.9 4.5 -1.4 0.8 0.2 0.1 0.0 -0.2 2.1 -0.2
Irritable Bowel Disease (IBD) 0.1 0.3 1.2 -0.8 0.3 0.5 -0.2 -0.0 -0.0 1.1 -0.0
Ulcerative Colitis (UC) 0.1 0.2 0.8 0.4 -0.4 0.1 -0.2 -0.3 0.1 -0.9 -0.2
Major Depression (MDD) 2.0 2.4 7.2 0.6 2.7 -1.4 2.4 -0.4 -0.3 1.6 -1.1
Reaction Time 0.5 0.9 2.5 -0.9 -0.7 0.8 -1.2 0.3 -1.6 0.6 1.1
Verbal and Numeric Reasoning (VNR) 0.6 1.4 2.9 0.5 0.2 -1.7 0.5 -1.4 -1.4 -0.8 -1.7
Breast Cancer 0.6 1.5 3.4 0.6 -1.4 1.6 -1.3 1.2 -0.1 -0.7 1.9
Ovarian Cancer 0.2 0.2 0.9 0.4 -0.0 -0.6 0.4 -0.3 -0.1 -0.9 -0.3
Prostate Cancer 1.2 1.7 4.2 -0.1 -0.6 1.8 -0.5 2.0 1.7 -0.4 1.6
Age at First Birth 0.5 0.7 2.2 1.0 -1.3 -0.2 -0.4 -0.1 -0.7 -1.5 0.4
Bipolar Disorder (2011) 1.4 1.4 3.8 0.7 1.3 1.0 0.4 0.1 2.0 1.9 0.2
Body Mass Index (BMI) (2010) 1.1 1.5 3.5 1.8 0.5 0.5 0.9 1.5 1.9 -0.4 1.1
Coronary Artery Disease (CAD) 0.5 0.6 1.8 -0.9 1.3 -0.4 0.8 -0.2 -0.7 0.5 -0.4
Crohns Disease (2012) 1.4 2.3 4.8 -1.1 0.9 1.8 -0.1 2.1 1.1 2.2 1.6
Mean Putamen Volume 0.7 0.8 5.1 -0.4 0.4 0.2 -0.1 -0.6 -0.0 2.3 -0.6
Fasting Glucose 0.2 0.2 0.5 0.7 0.1 0.0 -0.0 -0.7 -0.6 0.5 0.0
HbA1C 0.5 0.6 1.2 -1.1 0.2 -0.6 -0.2 -1.1 -0.8 0.5 -1.0
HDL Cholesterol 0.1 0.1 0.2 -0.0 -0.5 0.1 -0.3 0.2 -0.3 0.1 0.5
LDL Cholesterol 0.4 0.6 1.9 0.5 1.2 -0.9 1.4 -0.2 0.5 -0.2 -0.3
Lupus 0.5 0.7 2.8 -0.7 -1.7 -0.6 -0.6 -0.5 -0.2 -1.2 -0.5
Neuroticism (2016) 0.5 0.8 4.8 0.2 0.8 0.2 0.1 0.0 -0.4 2.2 -0.6
Primary Biliary Cirrhosis 0.2 0.3 1.6 -0.3 -0.2 -0.3 0.3 -0.4 -0.0 -1.3 0.1
Rheumatoid Arthritis 0.8 1.1 3.3 1.1 0.0 -1.8 1.0 -0.1 -0.9 -1.5 -0.1
Schizophrenia (2014) 1.2 2.6 7.0 1.8 -0.4 1.9 -0.8 2.3 0.6 0.7 2.6
Triglycerides 0.1 0.2 0.5 0.4 0.5 -0.2 0.6 0.0 -0.4 0.7 0.1
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.4 1.2 1.2 -0.5 0.8 -0.1 0.3 0.2 -0.5
Ulcerative Colitis 0.2 0.2 0.5 -0.7 0.2 0.6 -0.5 -0.6 0.0 0.3 -0.5
Blood Eosinophil Count 0.1 0.7 2.5 -0.4 -1.0 0.8 -1.6 -0.0 -0.5 0.8 0.2
Blood Platelet Count 0.1 1.0 2.7 -0.2 -1.1 1.3 -1.6 0.3 -0.7 0.2 1.4
Blood Red Count 1.5 14.1 30.0 -2.5 0.1 -5.1 1.6 -5.5 -4.0 1.4 -5.5
Blood White Count 0.3 2.1 5.6 -1.4 -0.2 -1.9 0.6 -2.4 -1.3 -0.6 -1.7
Heel T-Score 0.1 0.5 3.3 1.8 -0.2 -0.1 -0.1 -0.3 0.4 0.6 -0.5
BMI 0.2 1.0 3.0 1.7 0.4 -0.8 1.4 -0.5 1.1 -0.8 0.0
Height 0.1 1.5 3.1 -0.5 0.5 -1.8 1.0 -1.1 -1.1 1.7 -1.5
Waist Hip Ratio (WHR) 0.5 2.3 12.0 -3.5 -1.0 -0.8 -0.5 -1.2 -1.5 -0.6 -0.7
Systolic Blood Pressure 0.5 2.4 4.0 -0.5 2.0 -2.0 1.9 -0.9 -1.7 -0.7 -1.9
Smoking Status 0.6 1.5 6.2 -2.5 0.2 1.1 -0.5 1.3 -0.2 1.5 0.9
Allergy or Eczema 0.3 0.8 2.1 -0.5 -0.6 1.4 -1.5 -0.3 0.7 0.9 -0.2
Cardiovascular Disease 0.4 1.4 4.7 0.1 1.6 -1.4 2.2 -0.1 0.9 -0.8 -0.7
Hypothyroidism (self reported) 0.5 1.1 5.1 0.1 -0.8 -0.8 0.6 0.7 -1.1 -2.2 0.9
Respiratory disease 1.4 3.1 7.1 -0.1 2.5 1.2 1.3 1.5 2.4 2.7 0.8
Type 2 Diabetes (T2D) (2018) 0.5 0.9 2.4 -0.8 -0.2 1.5 -1.0 0.5 0.3 1.5 0.9
Lung FEV1/FVC ratio 0.4 2.3 4.5 1.9 -1.5 2.1 -2.0 0.8 0.8 -0.7 1.4
Lung FVC 0.2 0.9 2.1 1.4 -0.8 0.8 -0.9 0.5 0.3 -1.3 0.7
Neuroticism 2.1 5.1 11.3 -1.7 -0.1 3.4 -2.0 2.9 -0.2 3.0 2.4
Chronotype (morning person) 0.7 1.5 4.1 1.6 1.3 -0.9 2.0 0.2 1.0 -1.4 -0.3
Hair Pigment 0.0 0.6 2.1 -1.4 -0.2 0.6 -0.8 0.5 0.4 0.9 0.5
Tanning 0.1 1.4 3.4 -0.5 -0.0 -1.8 0.9 -1.8 -0.9 -1.0 -1.4
Hand grip strength (left) 0.6 1.6 5.1 1.1 0.8 1.3 0.0 0.9 1.6 2.2 0.8
Number of treatments/medications taken 0.2 0.3 2.0 -0.6 -0.0 -0.3 -0.2 -0.3 -1.4 -0.3 -0.2
Average weekly spirits intake 0.3 0.4 0.9 -0.6 0.8 -0.7 1.0 -0.2 -0.2 0.6 0.1
Sensitivity / hurt feelings 1.4 2.4 5.0 -1.7 -1.6 1.6 -2.2 0.5 -1.5 1.6 1.3
Frequency of depressed mood in last 2 weeks 1.7 2.4 5.4 -2.1 -0.5 1.5 -2.1 0.0 -2.3 1.4 0.8
Hearing difficulty/problems: Yes 0.3 0.5 1.3 0.1 -0.8 0.2 -0.4 1.2 -0.5 -0.6 1.1
Relative age of first facial hair 0.2 0.3 1.1 0.1 1.0 0.1 0.7 0.4 0.9 -0.0 -0.1
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 4.9 -1.9 -0.6 -1.1 -0.1 -0.6 -2.2 -1.5 -1.0
Ever used hormone-replacement therapy (HRT) 0.2 0.3 0.7 0.7 -0.1 0.4 -0.2 0.8 -0.5 0.1 0.8
Ever had hysterectomy (womb removed) 1.1 1.3 3.6 0.1 1.0 -1.9 1.8 -0.5 -0.4 -1.1 -0.6
Systolic blood pressure, automated reading 0.3 0.8 1.8 -0.0 1.1 -1.4 1.1 -0.6 -0.9 -0.3 -0.7
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 1.2 -0.6 -0.1 0.9 -0.9 0.1 -0.1 1.1 0.9
Angina 0.2 0.2 0.8 -0.8 -0.4 -0.3 -0.3 -0.9 0.0 -0.1 -0.4
Medication for hormone replacement therapy 1.9 2.1 5.8 1.1 -0.7 1.6 -0.8 2.4 1.0 0.8 2.1
Vitamin and mineral supplements 1.1 1.5 4.3 2.1 0.9 -1.5 1.9 -0.1 0.1 -1.0 -0.1
Supplements: Zinc 0.4 0.4 0.8 -0.0 -0.8 0.9 -0.6 0.6 0.2 -0.6 0.7
Medication: Co-codamol 0.2 0.3 0.8 -0.6 -0.5 -0.0 -0.3 -0.6 -0.5 -0.9 -0.2
Medication: Metformin 0.4 0.6 1.2 -1.1 0.4 0.5 -0.7 -0.8 -0.7 1.0 -0.7
Diabetes (father) 0.8 1.0 3.0 -0.0 1.7 -0.9 1.6 0.0 1.2 0.9 -0.2
Diabetes (mother) 1.2 1.6 3.0 -1.2 -1.3 1.7 -1.6 0.8 0.4 0.9 1.6
Severe depression (siblings) 0.3 0.3 0.5 -0.7 0.1 0.6 -0.7 0.2 -0.6 0.7 0.3
Pack years adult smoking proportion 0.1 0.2 0.8 0.4 0.1 -0.7 0.9 -0.1 -0.2 -0.3 0.0
Impedance of leg (right) 0.3 1.3 4.4 -2.1 0.1 -0.3 -0.4 -0.7 -2.0 0.2 -0.9
Leg fat-free mass (left) 0.2 1.0 3.0 0.8 0.8 -1.3 1.7 -0.2 1.2 -0.0 -0.5
Trunk fat percentage 0.1 0.4 1.2 0.4 0.3 -0.1 0.8 0.4 -0.2 0.7 1.1
Hand grip strength (right) 0.3 0.9 5.4 0.7 0.4 0.9 -0.5 -0.2 0.6 2.3 0.1
Townsend deprivation index at recruitment 0.8 1.2 2.9 0.4 1.3 -1.4 1.7 -1.2 -0.0 -0.3 -1.2
Current tobacco smoking 0.8 1.2 2.8 -1.7 1.4 -0.9 1.1 -0.6 0.0 1.5 -0.7
Average weekly fortified wine intake 1.1 1.3 3.8 0.4 -0.7 1.9 -1.3 1.2 0.7 0.4 1.3
Maternal smoking around birth 0.8 1.1 2.2 -0.7 -1.2 1.3 -1.4 1.1 0.1 0.2 1.5
Fed-up feelings 0.7 1.3 3.1 -0.7 0.3 1.2 -0.2 1.8 -0.5 1.5 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.1 2.8 -1.7 -0.6 0.7 -1.3 0.0 -1.6 1.1 0.3
Relative age voice broke 0.7 1.0 2.3 0.9 1.5 -0.1 1.4 0.6 1.5 0.0 0.6
Taking other prescription medications 0.3 0.4 0.8 -0.8 -0.1 0.9 -0.6 0.6 -0.6 0.5 0.5
Age when periods started (menarche) 0.3 0.6 2.3 -0.5 0.6 1.5 -0.8 0.8 0.5 0.6 0.6
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.8 1.3 0.8 -0.3 1.0 0.3 0.2 0.4 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 4.6 0.4 0.8 -0.5 0.7 -0.5 0.5 2.1 -0.1
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.5 0.2 0.7 -0.5 0.5 -0.4 -0.2 -0.1 -0.6
Qualifications: CSEs or equivalent 0.6 0.8 2.8 0.2 0.7 0.4 0.5 0.6 0.4 1.7 1.4
Serious illness, injury or assault to yourself 0.9 1.1 2.4 -1.2 -1.3 0.6 -1.1 0.7 -1.6 -0.4 0.9
High blood pressure 0.3 0.7 2.0 1.1 1.2 -0.8 1.4 0.3 0.2 -0.6 -0.1
Hayfever, allergic rhinitis or eczema 0.2 0.5 1.4 -0.6 0.1 0.5 -0.6 -0.9 0.3 0.8 -1.2
Multivitamins +/- minerals 1.2 1.6 4.4 -1.9 -1.1 1.5 -2.1 0.4 -0.2 0.6 0.4
Stomach or abdominal pain in last month 0.2 0.3 0.7 0.9 0.5 0.1 0.6 0.4 0.3 -0.2 0.6
Supplements: Glucosamine 0.4 0.6 1.5 0.3 -1.2 0.9 -1.2 0.3 0.5 -0.1 0.7
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 3.5 1.8 -0.7 -0.1 0.1 0.9 0.6 -1.9 0.8
Medication: Atenolol 0.2 0.2 0.6 -0.0 0.8 0.0 0.4 0.6 0.4 0.5 0.0
Medication: Levothyroxine sodium 1.1 1.8 4.3 1.6 -1.0 0.5 0.1 1.9 0.3 -1.6 2.1
Sitting height 0.3 1.8 4.9 -2.2 0.5 -1.3 0.4 -1.2 -1.1 1.0 -2.0
Chronic bronchitis/emphysema (father) 1.7 2.0 6.4 -2.5 -1.5 -0.0 -1.7 -1.0 -1.8 0.2 -0.4
High blood pressure (mother) 1.5 2.1 4.3 -0.7 2.1 -0.8 1.6 -0.6 1.8 1.5 -1.7
Body mass index (BMI) 0.1 0.6 1.7 1.3 0.5 -0.8 1.1 -0.8 0.6 0.1 0.2
Impedance of leg (left) 0.2 1.2 4.6 -2.1 0.3 -0.0 -0.5 -0.5 -1.8 0.7 -0.8
Leg predicted mass (left) 0.2 1.1 3.2 0.9 0.8 -1.4 1.8 -0.2 1.3 -0.1 -0.4
Trunk fat mass 0.1 0.5 1.5 0.4 0.8 -0.5 1.2 0.1 0.2 0.9 0.6
Waist circumference 0.0 0.1 0.4 0.6 -0.2 -0.3 0.5 -0.2 0.1 -0.2 0.6
Number of incorrect matches in round 0.4 0.7 1.8 0.4 0.0 1.3 -0.7 0.5 0.5 1.1 1.2
Past tobacco smoking 1.9 3.4 7.2 2.7 0.1 -2.7 1.7 -2.1 -0.0 -1.7 -1.7
Alcohol usually taken with meals 1.2 1.9 6.4 -0.2 -2.0 1.0 -2.5 -0.3 -1.8 0.4 -0.0
Nervous feelings 0.4 0.7 1.9 0.0 -0.6 0.9 -1.4 -0.5 -1.1 1.1 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 3.1 -1.2 1.4 0.6 -0.2 0.1 -0.4 1.8 -0.3
Hearing difficulty/problems with background noise 1.1 1.8 3.7 -0.6 -0.3 1.9 -1.2 1.8 -0.3 1.6 1.7
Hair/balding pattern: Pattern 2 1.5 1.9 5.4 1.1 1.9 -1.3 2.3 -0.6 1.6 0.7 -0.1
Had menopause 0.6 0.7 3.0 -0.1 -1.7 -0.2 -1.1 -0.0 -0.7 -1.0 0.6
Had other major operations 0.4 0.5 1.1 -0.8 0.4 -0.3 0.0 -0.9 -0.7 1.1 -0.6
Forced vital capacity (FVC) 0.3 1.1 2.2 0.3 1.4 -1.0 1.3 -0.9 1.2 -0.1 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 4.2 0.1 1.0 -0.7 0.8 -1.0 0.5 2.0 -0.3
Ever unenthusiastic/disinterested for a whole week 1.5 1.9 7.0 -0.5 -0.6 -1.4 -0.7 -1.3 -2.6 -0.7 -1.6
Qualifications: None of the above 0.7 1.4 3.3 -0.3 -0.8 1.4 -1.3 1.2 -1.3 0.7 1.8
Financial difficulties in last 2 years 0.9 1.2 3.1 -0.9 -0.5 -0.4 -0.8 -1.6 -1.8 0.5 -1.4
Mouth/teeth dental problems 0.7 1.0 2.5 -0.9 -1.2 -1.0 -0.7 -1.1 -0.7 -1.6 -0.6
Heart attack 0.9 1.2 3.2 -1.3 -0.8 1.2 -0.9 1.8 0.2 0.2 1.4
Allergy 0.1 0.3 0.7 0.9 -0.6 -0.6 0.0 -0.2 -0.4 -0.7 0.3
Pain all over the body in last month 1.0 1.1 3.2 0.1 1.8 0.6 0.9 1.4 0.8 1.1 0.8
Diabetes (self-reported) 0.3 0.4 1.6 -1.0 0.5 0.4 -0.3 -0.6 -0.3 1.3 -0.3
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 1.6 -0.4 0.1 -1.0 0.2 -1.1 -0.7 -1.1 -1.3
Medication: Ramipril 0.3 0.4 1.1 -1.0 0.7 -0.7 0.9 0.1 0.2 -0.1 -0.5
Medication: Simvastatin 0.7 1.0 3.0 -0.9 -0.6 -1.2 -0.3 -1.7 -1.1 -0.0 -1.0
Fluid intelligence score 0.7 1.4 4.6 -0.3 0.2 -1.6 0.4 -1.7 -0.8 -0.3 -2.1
Illnesses of siblings 1.3 1.8 4.1 1.0 1.2 1.5 0.8 2.0 1.2 0.3 1.8
Neuroticism score 1.3 2.6 5.7 -1.7 -0.1 2.2 -1.5 1.7 -0.7 2.4 1.4
Weight 0.1 0.7 1.8 0.5 0.8 -1.1 1.4 -0.8 0.4 0.5 -0.4
Impedance of arm (right) 0.2 1.0 3.1 -1.2 -0.2 1.3 -0.6 1.7 -0.6 0.4 1.0
Arm fat percentage (right) 0.2 0.6 1.6 1.2 0.5 0.3 0.8 0.5 0.6 0.7 1.3
Trunk fat-free mass 0.3 1.5 3.2 0.0 1.2 -1.8 1.5 -1.4 0.5 0.1 -1.7
Hip circumference 0.1 0.6 3.0 1.7 0.3 -0.1 0.8 0.2 0.7 0.3 0.6
Time employed in main current job 0.1 0.1 0.7 0.4 -0.3 -0.4 -0.2 -0.8 -0.1 0.0 0.0
Alcohol intake versus 10 years previously 1.1 1.7 5.1 0.8 -0.8 0.6 0.3 2.0 0.6 -1.4 2.3
Father’s age at death 1.1 1.5 4.5 1.9 1.3 -0.2 1.5 0.2 2.1 -0.0 -0.1
Worrier / anxious feelings 1.5 2.9 7.7 0.1 0.0 2.6 -1.1 2.8 0.3 1.4 2.4
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.1 -0.8 1.4 0.4 0.6 0.5 -0.2 1.3 0.5
Falls in the last year 0.7 0.9 3.2 -1.0 -0.3 1.5 -1.8 0.3 -0.1 0.8 0.0
Hair/balding pattern: Pattern 3 0.4 0.7 2.2 -1.5 -1.1 0.5 -0.9 0.5 -0.6 -0.3 0.4
Number of live births 0.1 0.2 0.8 0.9 -0.4 -0.0 -0.1 0.1 0.2 -0.2 0.7
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 1.1 0.4 0.7 -0.3 0.3 -0.7 0.9 -0.1 -1.1
Pulse rate 0.6 1.1 2.6 1.4 1.2 -0.5 1.6 0.1 1.4 -0.4 -0.2
Happiness 3.1 3.7 10.2 -0.6 -0.8 3.2 -2.9 1.6 -0.8 2.1 1.6
Noisy workplace 0.6 0.7 1.3 -0.6 1.0 -0.8 0.6 -1.2 -0.9 0.3 -1.0
Qualifications: A levels/AS levels or equivalent 0.4 0.8 1.6 0.7 0.6 -0.8 0.6 -1.0 1.3 -0.6 -1.3
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 1.7 -0.1 -0.3 -0.8 -0.0 -1.3 -1.2 -1.1 -1.2
Mouth/teeth dental problems: Dentures 0.3 0.6 2.2 -1.5 -0.1 0.6 -0.6 0.3 -1.0 0.7 0.1
Asthma 0.8 1.5 3.6 -0.5 1.9 -0.1 1.7 0.8 1.4 1.7 -0.0
Medication: Ibuprofen (e.g. Nurofen) 1.4 1.8 4.4 -0.2 2.1 -1.5 1.9 -0.8 0.6 0.7 -1.5
Medication: Cholesterol lowering 0.2 0.3 0.7 0.0 -0.5 0.8 -0.9 -0.1 0.5 0.5 0.6
Depression (self-reported) 1.6 1.9 4.4 0.6 0.6 2.1 -0.3 2.0 -0.1 1.9 1.7
Medication: Lansoprazole 0.7 0.8 1.7 0.3 -1.2 0.8 -0.8 0.7 -0.4 -0.9 1.3
Prospective memory result 0.7 0.9 1.7 1.0 1.2 1.1 0.5 0.8 1.3 0.4 0.8
Lung cancer (father) 1.0 1.2 4.0 0.7 2.0 -0.1 1.8 0.3 1.4 -0.0 0.5
Illnesses of mother 0.1 0.2 0.7 0.3 -0.8 -0.2 -0.3 -0.6 -0.0 -0.4 -0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 1.6 1.3 0.8 -0.3 0.6 -0.4 1.2 0.2 -0.8
Pulse wave Arterial Stiffness index 0.6 0.7 2.9 -0.4 1.2 -0.2 0.7 -0.4 0.7 1.7 -0.4
Impedance of arm (left) 0.2 1.1 2.2 -1.5 -0.6 1.2 -1.0 1.3 -1.1 0.3 0.9
Arm fat mass (right) 0.1 0.4 1.3 1.0 0.5 -0.6 1.1 -0.3 0.5 0.4 0.4
Trunk predicted mass 0.3 1.5 3.2 0.2 1.3 -1.8 1.5 -1.4 0.6 0.1 -1.7
Standing height 0.1 0.7 2.1 -1.4 0.8 -0.8 0.6 0.0 -0.3 1.0 -1.1
Length of working week for main job 0.2 0.2 0.6 -0.4 0.6 -0.5 0.8 0.0 -0.1 0.4 -0.4
Exposure to tobacco smoke at home 1.8 2.1 6.2 -1.0 1.9 0.1 1.4 -0.1 1.9 2.5 0.5
Breastfed as a baby 4.0 5.0 10.9 -1.1 -2.4 -1.2 -1.8 -2.1 -3.1 -3.3 -1.8
Tense / ‘highly strung’ 1.3 2.1 7.3 0.1 1.2 1.7 -0.3 1.5 -0.4 2.7 1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 8.6 -0.8 0.3 1.4 -1.3 0.2 -1.5 2.9 0.6
Hair/balding pattern: Pattern 4 0.4 1.0 3.0 -0.0 1.2 1.2 0.0 0.7 0.6 1.7 0.9
Birth weight of first child 0.6 1.1 5.2 2.3 -0.2 -0.6 0.6 -0.4 1.3 -0.7 0.1
Peak expiratory flow (PEF) 0.2 0.5 1.3 0.2 1.1 -0.7 0.7 -0.8 0.3 0.1 -1.0
Pulse wave reflection index 0.2 0.3 1.8 -0.0 -0.0 0.1 -0.6 -0.4 -0.3 1.3 -0.2
Ever highly irritable/argumentative for 2 days 0.7 0.8 4.1 0.9 0.9 0.5 0.1 0.7 -0.1 2.0 0.3
Loud music exposure frequency 0.8 0.9 2.9 -0.5 -1.4 -0.6 -0.4 0.8 -0.8 -1.7 0.2
Qualifications: O levels/GCSEs or equivalent 1.4 2.3 4.1 0.9 1.1 -2.0 2.0 -1.7 1.2 -1.0 -1.7
Mouth/teeth dental problems: Bleeding gums 1.3 1.7 4.6 0.8 2.1 0.3 1.7 1.0 1.6 1.3 0.2
Blood clot in the leg (DVT) 0.2 0.2 0.4 -0.3 0.6 -0.1 0.7 0.6 0.2 0.5 0.4
Medication: Paracetamol 0.2 0.4 0.8 -0.5 0.6 -0.7 0.9 -0.6 0.6 0.4 -0.5
Headache pain in last month 1.3 2.3 6.7 -0.5 0.9 -1.9 1.1 -2.6 0.4 0.1 -2.4
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.7 0.3 0.1 -1.2 0.5 -0.9 -0.7 -0.4 -1.7
Glaucoma (self-reported) 0.3 0.3 1.6 1.2 0.2 0.3 -0.1 0.0 0.1 0.2 0.8
Gout (self-reported) 0.7 0.9 3.3 -1.5 1.0 0.4 0.2 -0.2 0.5 1.8 -0.5
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 7.5 0.6 -1.3 -0.4 0.2 0.7 -0.7 -2.7 1.0
Medication: Amlodipine 0.6 0.9 2.6 -1.6 -1.3 0.1 -0.9 0.0 0.3 -1.2 0.3
Medication: Ventolin 100micrograms inhaler 0.8 1.0 3.9 0.3 2.0 -0.2 1.6 1.0 -0.2 0.4 0.6
Birth weight 0.1 0.2 0.4 0.5 -0.5 0.3 -0.2 -0.3 0.6 0.1 0.5
Chronic bronchitis/emphysema (mother) 0.8 1.0 3.1 -1.0 1.8 0.4 0.6 0.6 0.6 1.6 -0.2
High blood pressure (siblings) 0.4 0.6 2.5 -0.0 -1.6 0.1 -1.3 0.3 -0.3 -0.5 -0.1
Forced vital capacity (FVC), Best measure 0.4 1.5 3.2 1.1 1.8 -1.1 1.6 -0.6 1.3 0.3 -1.3
Body fat percentage 0.1 0.3 1.0 0.5 0.4 -0.2 0.9 0.2 -0.1 0.6 1.0
Leg fat percentage (right) 0.1 0.3 0.6 0.7 0.5 -0.3 0.8 -0.4 -0.1 0.4 0.4
Arm fat-free mass (right) 0.4 1.9 5.2 0.3 0.8 -2.3 1.6 -1.9 0.3 -0.1 -1.8
Exposure to tobacco smoke outside home 0.4 0.5 1.2 -0.7 0.8 -0.9 1.1 -0.4 0.7 0.5 -0.4
Comparative body size at age 10 0.3 0.8 2.8 0.7 1.2 -0.4 1.0 0.0 1.7 0.5 -0.7
Number of full brothers 0.4 0.5 1.2 1.1 -0.1 -0.7 0.9 0.5 0.9 -0.2 0.7
Worry too long after embarrassment 1.5 2.4 11.9 -2.0 0.6 1.0 -1.1 -0.5 -0.6 3.4 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 4.1 -2.0 -0.1 0.4 -0.7 -0.1 -1.2 0.6 -0.1
Wheeze or whistling in the chest in last year 0.5 0.9 2.2 -0.0 1.4 0.7 0.7 1.5 0.5 1.0 0.7
Number of children fathered 0.5 0.5 1.5 -0.3 -0.3 0.8 -0.6 1.1 0.4 0.5 1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.4 0.6 -1.2 0.6 -1.1 -0.2 -0.7 -1.0 0.7
Age at first live birth 0.3 0.6 1.4 0.2 -1.1 0.6 -1.2 -0.3 0.3 -1.1 -0.5
Pulse wave peak to peak time 0.7 0.8 3.1 0.2 -1.3 0.3 -0.8 0.5 -0.7 -1.8 0.4
Health satisfaction 0.9 1.1 3.1 0.9 1.4 0.3 1.2 1.8 0.5 0.2 1.2
Shortness of breath walking on level ground 0.7 0.9 2.7 -0.5 1.7 -0.9 1.2 -0.3 -0.9 0.7 -0.4
Qualifications: College or University degree 0.6 2.0 5.8 2.4 -0.2 -1.0 0.4 -1.1 1.7 -1.1 -1.8
Eye problems/disorders: None of the above 1.7 2.0 5.6 -1.8 0.7 -1.8 0.8 -1.5 -0.6 -0.1 -2.4
Mouth/teeth dental problems: Loose teeth 0.7 0.8 1.6 0.8 0.1 -0.9 0.4 -1.3 -1.2 -0.5 -1.2
Emphysema/chronic bronchitis 0.9 1.0 2.1 1.2 0.5 1.4 0.0 1.5 0.3 0.2 1.3
Medication for pain relief, constipation, heartburn 0.2 0.4 1.2 1.1 -0.7 -0.1 -0.2 -0.1 -0.8 -0.9 0.1
Neck or shoulder pain in last month 0.3 0.4 0.9 0.1 0.7 0.1 0.7 0.4 0.6 0.9 0.7
Medication: Blood pressure 0.4 0.7 2.6 -0.3 0.7 0.5 0.5 1.5 0.3 0.0 1.6
Angina (self-reported) 0.1 0.2 0.4 -0.6 -0.5 -0.0 -0.6 -0.6 0.0 -0.3 -0.1
Migraine (self-reported) 1.5 1.9 3.1 1.6 1.3 -1.5 1.7 -1.1 0.2 1.0 -1.7
Medication: Ibuprofen 1.8 2.2 4.7 0.0 2.1 -2.0 2.2 -1.0 0.4 0.3 -1.8
Medication: Allopurinol 0.8 1.1 3.1 -1.4 1.2 -0.1 0.5 -0.8 0.5 1.8 -1.0
Medication: Omeprazole 0.6 0.7 2.8 0.2 0.5 0.8 0.5 1.7 0.4 -0.6 1.2
Medication: Seretide 50 evohaler 0.3 0.4 1.3 -0.2 0.9 -0.2 0.7 -0.0 -0.4 1.1 -0.5
Mean time to correctly identify matches 1.4 2.6 5.0 -0.3 -1.0 2.1 -2.0 1.5 -1.4 1.6 2.2
Heart disease (mother) 1.0 1.3 3.5 0.3 1.4 -1.9 1.7 -0.6 -0.4 -0.6 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 1.8 0.9 -1.4 1.1 -1.2 1.2 0.0 -0.4 1.3
Whole body fat mass 0.1 0.5 1.5 0.6 0.8 -0.5 1.2 0.1 0.3 0.7 0.6
Leg fat mass (right) 0.1 0.5 1.5 1.0 0.6 -0.9 1.2 -0.6 0.3 0.3 0.1
Arm predicted mass (right) 0.4 1.8 4.8 0.4 1.0 -2.2 1.7 -1.7 0.5 0.1 -1.6
Pulse rate, automated reading 0.8 2.7 9.8 2.7 -0.0 -1.5 1.4 -0.4 -0.4 -3.1 -0.1
Alcohol intake frequency. 1.1 2.4 6.6 0.9 0.1 -2.6 1.7 -2.5 -1.0 -0.6 -1.3
Comparative height size at age 10 0.1 0.6 1.7 -0.1 0.4 -1.3 1.0 -0.5 -0.4 0.7 -0.8
Number of full sisters 0.7 0.8 1.9 -0.7 -1.4 -0.3 -0.8 -0.9 -0.8 -1.3 -0.5
Suffer from ‘nerves’ 0.4 0.6 1.1 0.4 -0.6 1.0 -0.9 0.5 -0.8 0.7 0.9
Overall health rating 0.7 1.5 4.6 0.7 2.1 -1.1 2.1 -0.3 -0.2 0.8 -0.4
Chest pain or discomfort 0.1 0.2 0.5 0.2 0.1 -0.3 0.6 0.2 0.3 0.3 0.7
Had major operations 0.9 1.1 2.9 -1.4 0.1 1.2 -1.0 0.7 -0.4 1.7 0.8
Age at last live birth 0.2 0.3 0.9 0.7 -0.4 0.1 -0.1 -0.2 0.7 -1.0 -0.4
Family relationship satisfaction 1.8 2.3 6.5 -0.7 -1.4 2.1 -2.5 0.8 -1.7 0.9 0.8
Leg pain on walking 0.1 0.1 0.5 -0.1 0.7 -0.2 0.4 0.1 -0.2 0.6 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 1.8 -1.3 -0.7 -0.8 -0.2 -1.2 -1.3 -0.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.5 0.4 -0.4 1.5 -0.6 0.7 1.6 0.4 1.0
Illness, injury, bereavement, stress in last 2 years 2.6 3.2 8.3 1.3 2.7 -0.6 2.6 0.8 2.9 0.5 -0.1
Medication: Aspirin 0.2 0.3 1.6 -0.1 0.2 -0.0 0.2 0.3 1.3 0.6 0.2
Supplements: Vitamin C 0.9 1.1 3.4 -0.9 1.8 -0.1 0.8 -0.2 -0.5 1.8 -0.4
Knee pain experienced in last month 1.1 1.7 3.9 2.0 1.1 0.1 1.7 1.1 1.5 -0.6 1.3
Hypertension (Self-reported) 0.2 0.5 1.1 1.1 1.0 -0.1 0.9 0.7 0.2 -0.3 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.9 2.2 5.4 2.3 -0.0 1.8 -0.4 1.7 1.3 0.5 2.0
Illnesses of father: Heart disease 0.6 0.9 3.7 0.7 1.9 -0.5 1.2 -0.3 0.6 0.7 -0.7
Illnesses of siblings: Diabetes 2.1 2.6 5.6 -1.8 -1.9 -1.5 -0.8 -2.4 -1.7 -0.8 -1.5
Smoking status: Previous 3.1 4.7 11.3 -1.8 -0.1 3.4 -1.7 2.9 0.7 1.9 2.6
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 1.6 -1.3 0.6 -0.8 0.6 -0.5 -0.5 0.8 -1.2
Whole body fat-free mass 0.2 1.3 3.0 0.5 1.1 -1.7 1.7 -0.9 0.9 0.1 -1.2
Leg fat-free mass (right) 0.2 0.8 2.3 0.8 0.7 -1.1 1.5 -0.1 1.3 0.2 -0.4
Arm fat percentage (left) 0.1 0.4 1.1 1.0 0.5 0.0 0.9 0.1 0.5 0.5 1.1
Average weekly red wine intake 1.0 1.4 4.8 -1.0 -0.2 2.2 -1.7 1.3 0.2 0.3 0.9
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.5 0.3 0.4 0.3 -0.1 -0.1 0.7 0.6 -0.1
Mood swings 0.5 0.9 1.4 -0.6 -0.9 1.0 -1.2 1.1 -1.1 0.4 1.1
Loneliness, isolation 0.3 0.4 1.0 -0.4 -0.0 0.8 -0.6 0.6 -0.3 1.0 1.0
Long-standing illness, disability or infirmity 0.4 0.6 3.3 -0.1 0.1 -0.2 0.2 0.3 -1.8 -1.1 0.2
Ever had bowel cancer screening 1.3 1.5 3.4 1.8 0.6 1.1 0.2 1.6 1.1 0.6 1.6
Diabetes diagnosed by doctor 0.2 0.4 1.1 -1.0 0.2 0.7 -0.7 -0.4 -0.2 0.9 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 1.8 1.3 1.1 -0.7 1.3 -0.1 0.5 0.7 -0.5
Friendships satisfaction 4.0 4.9 14.8 -0.9 -2.2 3.0 -3.9 1.3 -2.3 0.8 1.5
Qualifications: nursing, teaching 1.5 2.3 6.7 0.7 0.5 -2.1 0.9 -2.2 -0.0 -1.0 -2.6
Commuting to job workplace: Walk 1.3 1.4 3.0 -1.7 1.2 -1.0 0.4 -1.2 -0.7 1.1 -1.5
Eye problems/disorders: Cataract 2.0 2.3 6.3 1.9 -0.6 1.7 -0.5 1.9 0.9 -0.7 2.5
Mouth/teeth dental problems: Mouth ulcers 2.6 4.2 7.8 2.8 0.3 2.4 -0.1 2.8 2.3 1.3 2.2
Medication for cholesterol 0.2 0.3 1.3 -0.7 0.2 0.3 0.1 -0.4 1.1 0.1 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 2.5 -0.8 0.9 -1.0 0.8 -1.3 0.8 -0.3 -1.6
Back pain experienced in last month 0.1 0.1 0.7 -0.8 -0.2 0.2 0.1 0.1 0.3 0.1 0.4
Mineral and other dietary supplements 0.5 0.7 1.8 0.1 1.3 -0.7 1.1 -0.4 0.6 1.2 -0.7
Breast cancer (self-reported) 2.4 2.8 9.2 1.2 -1.1 2.0 -1.3 2.2 -0.1 0.4 3.0
Asthma (self-reported) 0.8 1.6 3.6 -0.4 1.9 -0.1 1.8 1.0 1.5 1.5 0.3
Osteoporosis (self-reported) 1.5 1.9 4.9 1.0 -1.1 1.6 -1.0 2.1 0.4 -0.0 2.2
Osteoarthritis (self-reported) 0.4 0.5 1.8 1.0 -0.7 -0.4 0.2 -0.2 -0.1 -1.3 0.9
Medication: Aspirin 0.2 0.3 1.8 0.1 0.1 -0.3 0.3 0.2 1.4 0.4 0.3
Medication: Gliclazide 1.7 1.9 4.7 -1.2 -1.8 1.6 -2.2 0.4 -1.3 -0.6 1.3
Illnesses of father: None of the above (group 1) 0.2 0.2 0.8 -0.6 -0.6 0.0 0.0 0.3 0.5 -0.9 0.2
Smoking status: Current 1.0 1.5 3.1 -1.8 1.5 -1.0 0.9 -0.9 -0.3 1.7 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.5 0.2 -0.8 1.1 -1.9 -0.9 -0.3 0.9 -0.3
Whole body water mass 0.2 1.2 2.5 0.5 1.1 -1.6 1.6 -0.9 0.9 0.2 -1.1
Leg predicted mass (right) 0.1 0.8 2.2 0.8 0.7 -1.0 1.5 0.0 1.3 0.1 -0.3
Arm fat mass (left) 0.1 0.4 1.0 0.9 0.5 -0.5 1.0 -0.3 0.3 0.4 0.5
Number of self-reported non-cancer illnesses 0.1 0.1 0.5 -0.3 0.5 -0.4 0.4 0.1 -0.7 -0.2 -0.0
Average weekly champagne plus white wine intake 0.7 1.0 1.8 -0.6 -1.3 0.9 -1.2 1.3 0.7 -0.8 0.8
Miserableness 0.9 1.6 6.9 -1.5 -0.2 1.2 -1.2 0.4 -0.8 2.6 0.4
Guilty feelings 0.7 1.0 2.3 -1.2 -0.2 1.2 -0.9 1.5 -0.6 1.0 1.0
Wears glasses or contact lenses 0.5 0.5 1.1 1.1 0.9 -0.4 0.7 -0.6 0.8 0.3 -0.8
Ever taken oral contraceptive pill 2.6 2.9 6.0 -2.0 -2.0 -0.7 -1.7 -1.1 -2.4 -1.8 -1.2
Hearing aid user 0.4 0.5 1.9 -0.6 0.0 0.2 -0.5 -0.4 -0.8 1.4 -0.5
Mother’s age at death 1.7 2.1 4.8 0.9 -1.6 2.2 -1.9 1.3 0.2 0.1 1.9
Financial situation satisfaction 0.7 0.9 1.9 -0.4 -0.4 1.4 -1.1 1.2 -0.7 1.2 0.6
Tinnitus: Yes, now most or all of the time 0.2 0.3 1.5 0.5 -0.3 -0.2 0.1 0.0 -0.3 -1.2 0.2
Commuting to job workplace: Public transport 0.7 0.9 3.4 -0.8 -1.0 0.2 -1.2 0.3 -1.8 -0.5 0.4
Eye problems/disorders: Glaucoma 0.6 0.7 1.9 1.1 0.2 1.1 -0.6 0.3 -0.1 1.4 1.0
Medication: Blood pressure 0.4 0.8 2.1 1.0 -0.9 -0.6 -0.1 -0.1 -1.3 -1.4 -0.6
Pain type(s) experienced in last month: Hip pain 1.0 1.3 2.7 -0.2 1.6 0.6 1.1 0.6 1.4 1.6 1.0
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.2 -0.2 -1.5 0.4 -1.2 0.1 -1.3 -1.1 0.7
High cholesterol (Self-reported) 0.1 0.2 1.0 0.4 0.6 0.0 0.4 0.3 0.2 1.0 0.4
Medication: Bendroflumethiazide 0.4 0.6 1.8 0.9 -0.6 0.2 0.1 1.1 -0.0 -1.4 0.6
Medication: Paracetamol 0.4 0.6 1.5 0.2 0.7 -1.1 1.2 -0.5 1.0 0.2 -0.6
Medication: Lisinopril 0.4 0.5 1.3 -0.5 0.7 -0.5 0.3 -0.9 -0.7 1.1 -0.6
Medication: Atorvastatin 0.3 0.4 0.9 -0.9 0.3 0.9 -0.6 0.7 0.2 0.8 0.2
Illnesses of father: High blood pressure 0.6 0.7 1.3 1.1 1.0 -0.9 1.0 -0.6 -0.3 -0.1 -1.1
Alcohol drinker status: Never 0.7 0.9 4.6 0.8 -0.3 -0.7 0.0 -2.1 0.5 -0.1 -0.9
Ever smoked 1.3 2.3 7.9 -2.8 -0.1 1.9 -1.4 1.1 0.1 1.7 0.9
Basal metabolic rate 0.2 1.1 2.8 0.4 1.1 -1.5 1.7 -0.9 0.8 0.2 -1.0
Leg fat percentage (left) 0.1 0.3 0.8 0.7 0.7 -0.2 0.9 -0.2 0.2 0.6 0.6
Arm fat-free mass (left) 0.2 1.2 2.9 0.8 0.8 -1.7 1.5 -1.2 0.4 0.0 -1.1
Number of operations (self-reported) 0.1 0.2 0.4 -0.5 0.0 0.5 -0.5 0.2 -0.7 0.2 0.4
Average weekly beer plus cider intake 0.1 0.1 0.4 0.4 0.1 0.3 0.1 0.1 -0.1 0.2 0.6
Irritability 1.2 2.1 10.2 -1.7 1.3 1.2 -0.6 0.5 -0.3 3.2 0.0
Risk taking 0.4 0.6 1.8 -0.2 -0.6 -0.8 -0.3 -1.3 -0.9 0.2 -1.0
Ever had prostate specific antigen (PSA) test 1.3 1.5 3.1 -1.2 1.1 1.7 -0.1 1.3 1.0 1.8 0.8
Fractured/broken bones in last 5 years 0.8 1.1 3.9 -0.3 -1.1 -0.4 -1.0 -0.4 -2.0 -1.3 -0.4
Age started oral contraceptive pill 0.4 0.5 1.7 0.6 -1.1 -0.3 -0.5 -0.2 -0.2 -1.3 0.0
Diastolic blood pressure, automated reading 1.1 3.5 7.6 1.5 1.8 -2.8 2.6 -1.3 -0.5 -1.7 -1.8
Ever depressed for a whole week 0.9 1.1 3.1 -0.1 -1.4 0.2 -1.8 -0.7 -1.7 -0.6 -0.6
Unable to work because of sickness or disability 0.4 0.5 1.3 -1.1 0.1 0.7 -0.4 0.4 -0.9 1.1 0.4
Commuting to job workplace: Cycle 1.5 1.9 5.2 -0.6 0.5 -2.1 0.7 -1.7 -1.1 -0.1 -2.3
Myopia 1.4 2.0 5.1 -1.7 -2.1 0.6 -2.3 -0.8 -1.5 -0.8 -0.1
Vascular/heart problems diagnosed by doctor 0.1 0.4 1.0 -0.8 -0.8 0.7 -1.0 -0.2 -0.2 0.5 0.1
Cholesterol lowering medication 0.2 0.3 1.3 -0.2 0.3 0.4 -0.4 -0.1 -0.6 1.1 0.3
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.5 0.7 0.3 0.9 0.3 1.6 0.3 -0.6 1.5
Pain experienced in last month 0.7 1.1 3.1 -0.2 -1.4 -0.3 -1.1 -0.1 -1.8 -1.4 -0.7
Supplements: Calcium 0.4 0.4 1.4 1.2 -0.3 -0.4 0.2 0.2 -0.5 -1.1 -0.0
Basal cell carcinoma (self-reported) 0.7 0.8 2.3 -1.0 -1.5 -0.2 -1.0 -1.2 -0.6 -0.4 -0.3
Heart attack/myocardial infarction (self-reported) 0.9 1.1 3.2 -1.4 -0.7 1.1 -0.8 1.8 0.2 0.2 1.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.0 -0.3 0.5 0.3 0.6 1.0 0.4 0.6 1.0
Heart disease (siblings) 1.0 1.3 3.2 -1.2 -0.6 -1.5 -0.0 -1.0 -1.8 -1.0 -0.9
Alcohol drinker status: Previous 0.3 0.4 1.0 0.2 0.2 -0.4 0.8 1.0 0.3 -0.3 1.0
Pack years of smoking 0.2 0.3 0.8 0.6 0.0 -0.8 0.9 -0.3 -0.2 -0.8 -0.2
Impedance of whole body 0.2 1.1 3.8 -1.9 -0.4 0.9 -1.0 0.8 -1.6 0.3 0.4
Leg fat mass (left) 0.1 0.6 1.8 1.0 0.8 -0.8 1.3 -0.4 0.5 0.3 0.1
Arm predicted mass (left) 0.2 1.2 2.7 0.8 1.0 -1.6 1.6 -1.0 0.8 0.2 -1.0