TWAS hub - BTRC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1060	0.0420	0.00063	0.017	0.027	0.029	0.030	0.023	3.2e-03	2.5e-04	1.5e-04	1.2e-04	8.0e-04
2	GTEx	Artery Tibial	0.1628	0.0568	0.00012	0.013	NA	0.050	NA	0.034	2.8e-02	NA	8.6e-05	NA	1.1e-03
3	GTEx	Colon Sigmoid	0.1550	0.0690	0.00320	0.167	NA	0.093	NA	0.141	1.6e-06	NA	3.5e-04	NA	1.1e-05
4	GTEx	Stomach	0.1230	0.0570	0.00780	0.041	NA	0.041	NA	0.018	4.6e-03	NA	4.9e-03	NA	4.3e-02
5	METSIM	Adipose	0.0427	0.0191	0.00180	0.054	0.024	0.048	0.045	0.051	1.4e-08	1.2e-04	9.8e-08	2.3e-07	3.3e-08
6	ROSMAP	Brain Pre-frontal Cortex	0.0489	0.0225	0.00110	0.012	0.019	0.024	0.020	0.024	1.0e-02	1.6e-03	3.5e-04	1.3e-03	3.6e-04
7	YFS	Blood	0.0112	0.0075	0.04600	0.007	0.000	0.005	0.002	0.007	1.3e-03	2.8e-01	4.8e-03	4.6e-02	2.4e-03
8	TCGA	Lung Squamous Cell Carcinoma	0.0610	0.0275	0.00049	0.004	0.036	0.033	NA	0.024	1.0e-01	5.4e-05	1.0e-04	NA	8.2e-04
9	TCGA	Skin Cutaneous Melanoma	0.1590	0.0830	0.00200	0.075	0.090	0.036	NA	0.072	4.9e-03	2.2e-03	4.0e-02	NA	5.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Smoking Status	5.9	14.0	26.8	-2.6	-4.3	-4.5	-2.4	-4.5	-4.0	-3.0	-1.8	-5.2
Current tobacco smoking	5.5	9.0	13.3	-2.8	-3.6	-3.6	-2.5	-3.6	-2.8	-2.2	-2.4	-3.1
Systolic Blood Pressure	5.3	26.6	52.6	-1.8	-4.5	-6.2	-4.4	-6.3	-7.2	-4.1	-2.0	-6.7
Smoking status: Current	5.3	8.4	13.6	-2.7	-3.7	-3.5	-2.2	-3.5	-2.7	-1.8	-2.0	-3.2
Suffer from ‘nerves’	5.1	8.0	15.6	-1.0	-3.2	-3.7	-1.9	-3.8	-3.2	-1.7	-0.3	-4.0
Pain type(s) experienced in last month: Hip pain	5.0	6.3	16.8	-2.5	-2.3	-2.2	-3.2	-2.2	0.2	-2.6	-4.1	1.1
Townsend deprivation index at recruitment	4.7	6.6	10.6	-2.2	-3.2	-2.6	-2.5	-2.5	-2.8	-2.0	-2.8	-2.3
Commuting to job workplace: Walk	4.7	5.0	9.0	-2.0	-1.9	-3.0	-2.5	-3.0	-2.3	-1.0	-1.5	-2.1
Fluid intelligence score	4.0	8.2	13.8	2.2	3.0	3.5	2.5	3.5	3.7	1.6	0.4	3.7
Schizophrenia (2014)	3.8	8.4	17.0	-2.1	-2.6	-3.4	-3.2	-3.5	-1.2	-3.4	-4.1	-0.4
Mean Putamen Volume	3.5	4.0	7.6	1.4	1.7	2.8	2.0	2.7	1.7	1.9	0.6	2.3
Migraine (self-reported)	3.5	4.3	6.9	-0.3	2.5	2.6	1.4	2.6	2.6	0.2	1.9	2.5
Worry (Nagel 2018)	3.3	7.0	22.3	0.6	-2.1	-3.4	-0.6	-3.5	-3.1	-0.8	1.2	-4.7
Bipolar Disorder (2011)	3.2	3.1	5.3	-1.2	-2.3	-2.0	-1.6	-2.0	-1.7	-1.3	-1.8	-1.6
Bipolar Disorder or Schizophrenia	3.0	7.3	14.1	-1.6	-2.1	-3.3	-3.0	-3.4	-1.8	-3.0	-3.8	-1.1
Schizophrenia (2018)	3.0	6.2	15.1	-1.5	-2.3	-2.9	-2.5	-3.0	-1.9	-2.4	-3.9	-0.6
Number of incorrect matches in round	3.0	5.0	9.4	-1.6	-2.1	-2.1	-2.4	-2.1	-2.8	-1.8	1.8	-3.1
Qualifications: None of the above	3.0	6.5	10.5	-1.9	-3.2	-2.8	-2.3	-2.8	-3.0	-2.5	-1.7	-2.3
Supplements: Vitamin C	3.0	3.5	5.6	1.4	1.3	2.4	1.0	2.3	2.1	1.7	2.4	1.8
Intelligence (Savage-Jansen 2018)	2.9	8.9	17.3	1.9	4.2	3.0	3.0	3.0	3.9	1.9	0.2	3.7
Hand grip strength (left)	2.9	7.7	18.4	-1.7	-4.0	-2.2	-1.3	-2.1	-4.1	-2.0	-0.3	-4.3
Maternal smoking around birth	2.9	4.2	6.4	-2.2	-2.3	-2.3	-1.8	-2.4	-0.9	-2.4	-2.5	-0.8
Medication: Ventolin 100micrograms inhaler	2.9	3.8	5.8	2.2	1.1	1.8	2.1	1.8	2.3	2.4	2.0	1.4
Osteoporosis (self-reported)	2.9	3.6	5.7	-1.4	-2.1	-2.4	-2.0	-2.4	-1.5	-2.0	-2.0	-0.7
Systolic blood pressure, automated reading	2.8	8.3	14.7	-1.3	-2.4	-3.8	-3.0	-3.8	-3.8	-2.0	-1.3	-2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.7	3.5	7.9	0.5	-1.7	-2.1	-1.8	-2.1	-2.4	-1.2	1.4	-2.8
Mouth/teeth dental problems	2.5	3.9	7.4	1.5	1.0	2.7	2.7	2.7	0.9	1.9	2.1	1.2
Supplements: Fish oil (including cod liver oil)	2.5	3.3	9.7	-1.1	-1.6	-1.7	-1.3	-1.7	-2.1	-3.1	-0.6	-2.0
Age when periods started (menarche)	2.4	5.8	9.3	2.7	3.0	3.0	2.7	3.1	2.0	1.2	1.8	1.1
Number of children fathered	2.4	2.7	4.6	1.3	1.7	1.8	2.1	1.8	1.1	2.2	1.5	0.8
Ulcerative Colitis	2.3	3.4	5.5	-2.2	-1.6	-1.7	-2.1	-1.6	-1.8	-2.3	-1.4	-1.6
Qualifications: NVQ or HND or HNC or equivalent	2.3	2.8	5.8	-1.3	-1.5	-1.5	-1.7	-1.5	-1.5	-2.4	-2.3	-0.3
Mineral and other dietary supplements	2.3	3.0	8.6	0.6	1.6	1.6	1.3	1.6	2.3	2.9	0.2	2.0
Verbal and Numeric Reasoning (VNR)	2.2	5.4	14.8	0.6	2.6	2.4	1.4	2.3	3.5	1.0	-0.6	3.8
Primary Biliary Cirrhosis	2.2	3.2	8.0	-0.8	0.6	2.0	1.6	2.0	2.8	2.1	1.2	1.8
Number of live births	2.2	3.2	9.0	1.1	1.5	1.8	0.7	1.8	2.5	1.6	0.3	3.0
Lung cancer (father)	2.2	2.5	6.0	-0.6	-1.0	-2.1	-0.1	-2.0	-1.2	-2.4	-2.0	-1.3
Alcohol drinker status: Previous	2.2	2.5	7.3	1.5	1.3	1.2	2.0	1.2	2.7	1.2	0.1	1.6
Relative age of first facial hair	2.1	4.4	8.7	1.8	2.1	2.4	3.0	2.3	2.3	1.4	0.8	2.0
Hearing difficulty/problems with background noise	2.1	3.3	6.8	1.7	2.6	1.9	2.6	1.9	1.9	0.4	0.2	1.4
Mouth/teeth dental problems: Dentures	2.1	3.5	7.1	-0.4	-1.5	-2.6	-1.6	-2.7	-1.9	-1.1	-2.0	-1.9
Prospective memory result	2.1	2.6	7.8	-1.3	-0.8	-1.2	-0.8	-1.2	-2.3	-1.1	1.6	-2.8
Angina (self-reported)	2.1	2.8	5.1	-1.2	-2.3	-2.0	-1.9	-2.0	-1.1	-0.9	0.7	-2.1
Schizophrenia vs Biploar Disorder	2.0	2.6	5.7	-2.0	-1.2	-1.3	-1.4	-1.3	-1.3	-2.4	-2.3	-0.0
Average weekly fortified wine intake	2.0	2.3	7.8	1.0	2.8	1.5	0.7	1.5	1.6	1.1	1.2	1.4
Commuting to job workplace: Public transport	2.0	2.4	3.6	-1.9	-1.9	-1.8	-0.8	-1.8	-1.5	-1.2	-0.6	-1.8
Body Mass Index (BMI) (2010)	1.9	2.6	8.2	-1.4	-0.5	1.3	0.3	1.3	2.4	1.0	-1.5	2.9
Neuroticism	1.9	4.6	15.3	1.9	-1.2	-2.6	0.5	-2.6	-2.6	-0.4	0.9	-3.9
Number of treatments/medications taken	1.9	3.4	5.7	-1.2	-1.0	-2.4	-2.3	-2.4	-2.0	-1.9	-1.1	-1.7
Hair/balding pattern: Pattern 2	1.9	2.4	9.8	-3.1	-1.2	-1.5	-2.0	-1.5	-0.1	-0.4	-1.4	0.3
Noisy workplace	1.9	2.4	6.5	-1.7	0.3	-0.9	-2.6	-0.9	-0.0	-2.4	-1.9	1.0
Qualifications: A levels/AS levels or equivalent	1.9	4.2	11.3	0.9	3.4	2.2	1.6	2.3	2.5	0.9	1.6	1.9
Pulse wave reflection index	1.9	2.4	7.4	1.7	0.1	1.8	0.9	1.8	1.3	1.2	2.7	0.6
Number of operations (self-reported)	1.9	2.8	5.7	1.6	1.6	2.4	1.5	2.3	1.0	0.9	1.5	1.7
Respiratory disease	1.8	3.9	11.3	3.4	1.8	2.1	1.5	2.1	1.6	1.1	1.5	1.9
Impedance of leg (left)	1.8	8.8	28.7	2.6	3.2	3.4	5.4	3.4	-1.4	1.3	2.5	-0.5
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	4.1	0.6	-1.5	-2.0	-0.6	-2.0	-1.4	-1.4	-0.6	-2.0
Breast cancer (self-reported)	1.8	2.1	4.9	-1.0	-1.2	-2.2	-1.3	-2.2	-0.9	-0.7	-1.9	-0.7
Allergy or Eczema	1.7	4.4	11.4	1.7	2.8	1.9	0.9	1.8	2.6	1.3	1.0	3.4
Angina	1.7	2.2	4.2	-0.9	-1.8	-1.8	-1.7	-1.8	-1.1	-0.9	0.8	-2.1
Medication for hormone replacement therapy	1.7	1.8	8.9	-0.2	-0.3	1.7	0.2	1.7	0.4	1.2	3.0	0.4
Serious illness, injury or assault to yourself	1.7	2.1	4.9	1.2	2.2	1.7	0.3	1.6	1.3	1.4	-0.2	1.9
Tense / ‘highly strung’	1.7	2.8	6.3	-0.6	-1.5	-2.5	-0.9	-2.5	-1.7	-0.6	0.5	-2.5
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	10.7	0.3	3.3	1.8	0.3	1.8	1.6	0.5	1.6	1.5
Back pain experienced in last month	1.7	2.5	6.4	-1.5	-1.9	-1.1	-1.6	-1.2	-1.6	-1.5	-2.5	-0.2
Supplements: Calcium	1.7	1.9	4.4	-0.6	-1.7	-2.1	-1.7	-2.1	-0.7	-0.7	-0.9	-0.7
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	3.1	0.8	1.4	1.6	1.4	1.6	1.8	1.4	0.8	1.7
Impedance of leg (right)	1.6	7.8	28.4	2.3	2.8	3.2	5.3	3.2	-1.1	1.3	2.3	-0.3
Medication: Atenolol	1.6	2.0	6.2	1.1	-0.8	-1.7	-0.6	-1.7	-1.5	-1.2	0.0	-2.5
Falls in the last year	1.6	2.2	5.0	-1.0	-0.8	-2.0	-2.0	-2.1	0.5	-0.7	-2.2	-0.1
Qualifications: College or University degree	1.6	5.0	9.7	0.3	1.9	2.2	1.6	2.1	3.0	3.0	1.2	3.1
Vascular/heart problems diagnosed by doctor	1.6	4.4	11.3	0.5	0.8	2.7	1.5	2.7	2.9	1.6	0.3	3.4
Impedance of whole body	1.6	8.1	25.1	2.4	3.9	3.3	5.0	3.3	-0.6	1.1	1.9	0.1
LDL Cholesterol	1.5	2.3	6.5	-1.6	-1.4	-0.7	-2.4	-0.8	-1.0	-1.0	-2.5	1.0
Lupus	1.5	2.3	4.2	0.7	1.7	1.6	1.6	1.7	2.0	1.5	1.4	1.1
Medication: Metformin	1.5	2.1	9.1	0.3	0.8	0.1	0.3	0.2	2.0	0.6	-3.0	2.1
Trunk fat-free mass	1.5	8.4	19.4	-3.1	-4.4	-2.7	-4.2	-2.7	-1.9	-2.4	-1.0	-2.2
Worrier / anxious feelings	1.5	2.9	9.9	0.5	-0.9	-1.9	0.2	-1.9	-2.2	-0.7	1.4	-3.1
Pulse rate	1.5	2.6	8.2	-0.9	0.3	-2.0	-1.8	-2.0	-0.3	-1.6	-2.9	0.2
Impedance of arm (left)	1.5	7.2	20.2	2.1	4.0	3.0	4.5	3.0	0.5	1.4	1.6	0.5
Trunk predicted mass	1.5	8.7	19.6	-3.1	-4.4	-2.8	-4.3	-2.8	-1.9	-2.4	-1.1	-2.2
Hypertension (Self-reported)	1.5	4.1	10.6	-0.2	-0.5	-2.5	-1.5	-2.5	-3.0	-1.6	-0.4	-3.3
Ever taken oral contraceptive pill	1.5	1.7	3.5	0.2	0.3	1.3	1.3	1.3	1.8	1.2	1.9	1.3
Basal cell carcinoma (self-reported)	1.5	1.8	10.3	-1.4	0.1	-1.1	-0.5	-1.0	-0.3	-3.2	-0.3	-1.2
Pack years adult smoking proportion	1.4	2.1	4.3	-1.4	-1.5	-1.1	-2.1	-1.2	-0.5	-1.7	-2.0	0.0
Trunk fat percentage	1.4	5.5	17.4	-0.5	2.1	2.6	0.8	2.7	2.6	1.6	-1.7	4.2
Hand grip strength (right)	1.4	3.7	10.3	-1.5	-3.2	-1.4	-0.9	-1.3	-2.5	-0.9	-0.4	-3.0
Nervous feelings	1.4	2.6	10.6	0.7	-0.7	-1.8	0.7	-1.8	-2.0	0.6	0.6	-3.3
Diabetes (self-reported)	1.4	2.1	5.4	1.3	0.6	0.7	0.8	0.7	2.1	1.2	-1.9	2.3
Depression (self-reported)	1.4	1.7	2.9	-0.5	-1.2	-1.7	-1.6	-1.7	-0.8	-1.2	-1.7	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	5.8	0.7	-0.8	-1.8	-0.5	-1.8	-1.9	-1.3	0.6	-2.4
Number of full sisters	1.4	1.7	4.7	1.7	0.5	0.9	2.2	0.9	0.5	1.6	1.5	-0.7
Overall health rating	1.4	3.0	6.6	-1.5	-1.8	-2.2	-1.9	-2.2	-0.1	-1.5	-2.6	-0.1
Diabetes diagnosed by doctor	1.4	2.4	7.3	1.2	0.4	0.3	0.5	0.3	2.3	1.0	-2.7	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.0	7.2	0.8	-0.2	1.9	2.0	1.9	-0.7	2.7	2.5	-0.6
Whole body water mass	1.4	8.0	20.0	-3.2	-4.2	-2.6	-4.5	-2.5	-1.3	-2.1	-1.6	-1.4
Arm fat-free mass (left)	1.4	6.9	16.8	-3.0	-4.1	-2.3	-4.0	-2.2	-1.3	-1.9	-1.9	-1.0
Major Depression (MDD)	1.3	1.5	4.1	-0.8	-1.4	-1.5	0.2	-1.5	-1.2	-0.9	-0.1	-2.0
Relative age voice broke	1.3	2.0	5.1	1.2	0.4	1.1	2.3	1.1	1.8	1.8	1.1	1.0
High blood pressure	1.3	3.6	9.4	-0.3	0.0	-2.2	-1.3	-2.2	-2.9	-1.7	-0.0	-3.1
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	5.1	0.3	2.3	1.1	0.7	1.1	2.1	0.7	1.1	1.1
Impedance of arm (right)	1.3	6.1	21.8	2.4	3.1	2.7	4.7	2.7	0.2	1.4	1.5	0.2
Length of working week for main job	1.3	1.5	3.6	0.1	1.1	1.9	0.7	1.9	0.5	1.1	-0.0	1.7
Hair/balding pattern: Pattern 4	1.3	3.1	8.1	0.8	0.2	1.4	1.6	1.5	-2.8	-0.6	2.4	-2.6
Body fat percentage	1.3	5.1	17.2	-0.5	1.8	2.3	0.6	2.3	2.6	1.7	-2.0	4.2
Arm fat-free mass (right)	1.3	6.6	19.1	-3.2	-3.8	-2.1	-4.4	-2.0	-1.4	-1.7	-1.4	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.6	3.1	0.4	-0.3	-1.6	-1.1	-1.6	-1.3	0.7	1.5	-1.8
Comparative height size at age 10	1.3	6.9	16.4	-2.5	-2.3	-2.3	-3.6	-2.2	-2.1	-4.0	-1.1	-2.4
Illnesses of father: Heart disease	1.3	1.8	4.2	0.6	0.3	1.4	1.6	1.4	-1.7	1.1	2.1	-1.2
Whole body fat-free mass	1.3	7.5	19.6	-3.2	-4.1	-2.4	-4.4	-2.4	-1.2	-2.0	-1.5	-1.3
Arm fat percentage (left)	1.3	5.0	18.5	-0.8	1.6	1.7	-0.1	1.7	3.0	1.6	-2.5	4.3
Qualifications: nursing, teaching	1.3	2.0	3.5	0.4	1.7	1.9	0.6	1.8	1.0	1.8	0.8	1.7
Eye problems/disorders: Glaucoma	1.3	1.6	4.9	-1.4	0.3	-0.2	-1.7	-0.2	1.5	-0.1	-1.4	2.2
Myopia	1.3	1.9	3.8	0.7	-2.0	-2.0	0.1	-1.9	-0.9	-0.3	-1.4	-1.6
Arm predicted mass (left)	1.3	6.8	16.6	-3.0	-4.0	-2.3	-4.1	-2.2	-1.3	-2.0	-1.8	-0.9
Neuroticism (Nagel 2018)	1.2	2.8	9.1	1.8	-0.7	-1.8	0.9	-1.9	-1.7	-0.2	1.2	-3.0
Sensitivity / hurt feelings	1.2	2.0	7.9	1.1	-1.5	-1.1	1.4	-1.0	-1.4	-0.1	0.9	-2.8
Leg fat-free mass (left)	1.2	6.1	18.8	-3.1	-3.5	-1.9	-4.3	-1.9	-0.3	-1.6	-2.0	-0.2
Glaucoma (self-reported)	1.2	1.4	5.2	-0.8	0.1	0.0	-1.2	0.0	1.7	0.4	-1.4	2.3
Leg fat percentage (right)	1.2	4.3	14.7	-0.3	1.4	2.1	0.8	2.2	2.3	1.8	-1.7	3.8
Mouth/teeth dental problems: Loose teeth	1.2	1.4	4.3	-1.3	0.5	0.6	-1.3	0.5	2.1	-0.3	-0.6	1.9
Arm predicted mass (right)	1.2	6.1	17.5	-3.0	-3.6	-2.1	-4.2	-2.0	-1.1	-1.8	-1.5	-0.8
Leg fat-free mass (right)	1.2	6.4	20.6	-3.0	-3.5	-2.1	-4.5	-2.1	-0.6	-1.8	-1.8	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.2	0.1	0.4	1.7	0.1	1.6	1.8	0.4	0.3	1.6
Medication: Gliclazide	1.2	1.4	7.6	-0.5	0.8	0.2	-0.4	0.2	1.2	-0.3	-2.8	1.4
Leg predicted mass (right)	1.2	6.3	20.3	-3.0	-3.5	-2.1	-4.5	-2.0	-0.6	-1.7	-1.8	-0.6
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.1	0.3	-2.3	-1.5	-1.2	-1.4	0.2	1.4	0.5	-0.7
Bipolar Disorder (2018)	1.1	1.7	3.0	-0.7	-0.5	-1.7	-1.6	-1.7	-0.7	-1.7	-1.2	-1.0
Ulcerative Colitis (UC)	1.1	2.2	5.0	-2.1	-1.1	-0.6	-1.9	-0.4	-1.8	-2.2	-0.2	-1.1
Cardiovascular Disease	1.1	3.6	8.5	0.4	-0.7	-2.5	-1.7	-2.5	-2.5	-0.8	-1.0	-2.9
Type 2 Diabetes (T2D) (2018)	1.1	2.0	11.8	-0.0	-0.6	-0.1	-0.0	-0.1	1.5	0.4	-3.4	1.8
Ever had hysterectomy (womb removed)	1.1	1.3	3.5	0.4	-1.2	-1.0	-1.0	-1.0	-1.9	-1.2	-0.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	4.2	0.6	1.9	1.3	2.0	1.3	1.2	1.9	-1.1	2.0
Leg predicted mass (left)	1.1	6.0	18.9	-3.2	-3.4	-1.9	-4.3	-1.8	-0.3	-1.6	-2.0	-0.2
Had other major operations	1.1	1.3	2.2	1.3	0.7	1.4	0.7	1.4	0.8	1.4	0.5	1.5
Heart attack	1.1	1.5	5.4	0.3	-2.3	-1.2	-0.9	-1.2	0.4	1.7	0.7	-0.6
Arm fat percentage (right)	1.1	4.2	16.1	-0.8	1.1	1.5	0.0	1.5	2.7	1.5	-2.5	4.0
Exposure to tobacco smoke at home	1.1	1.2	3.5	-0.8	0.2	-0.4	-1.8	-0.4	-1.9	-1.1	-1.3	-0.2
High blood pressure (siblings)	1.1	1.6	4.3	-0.5	-0.1	-0.4	-0.6	-0.4	-2.0	-1.3	1.8	-2.1
Medication: Ibuprofen	1.1	1.3	5.4	-0.6	-0.1	0.8	-0.7	0.8	0.3	-0.9	-1.7	2.3
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.0	1.0	1.7	1.6	1.4	1.6	0.2	-0.4	0.1	0.7
Medication: Aspirin	1.1	1.5	3.8	-1.1	-1.9	-1.6	-0.6	-1.6	0.2	1.0	-1.4	-0.3
Mother’s age at death	1.1	1.4	4.6	1.3	0.5	0.4	2.1	0.4	-1.3	0.9	0.7	-1.5
Basal metabolic rate	1.1	6.0	16.6	-3.1	-3.6	-2.0	-4.1	-2.0	-0.8	-1.8	-1.8	-0.6
Leg fat percentage (left)	1.1	3.8	13.2	-0.2	1.5	1.9	0.6	2.0	2.3	1.7	-1.8	3.6
Pack years of smoking	1.1	1.6	3.6	-1.2	-1.3	-1.2	-1.9	-1.2	-0.3	-1.4	-1.7	0.0
Irritable Bowel Disease (IBD)	1.0	2.5	6.4	-2.5	-0.9	-1.0	-2.3	-0.9	-1.1	-2.3	-0.6	-0.9
Hypothyroidism (self reported)	1.0	2.3	8.8	-0.5	-1.4	-1.5	0.4	-1.4	-2.0	-0.7	1.0	-3.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	6.6	0.3	0.6	-0.2	0.6	-0.2	2.6	0.3	-0.9	1.2
Hayfever, allergic rhinitis or eczema	1.0	2.1	5.1	1.2	2.1	0.9	0.6	0.9	2.2	0.7	1.1	2.1
Medication: Levothyroxine sodium	1.0	1.7	3.8	0.0	-1.7	-1.7	-0.1	-1.7	-1.7	-0.6	-0.1	-1.9
Neuroticism score	1.0	2.1	6.0	0.8	-0.9	-2.2	0.3	-2.2	-1.5	-0.4	0.2	-2.5
Father’s age at death	1.0	1.3	2.5	1.4	1.6	1.0	1.2	1.1	0.6	1.4	1.3	0.2
Pulse wave Arterial Stiffness index	1.0	1.2	3.5	1.8	-0.5	0.3	-0.1	0.3	1.2	1.6	1.9	-0.0
Pulse wave peak to peak time	1.0	1.2	3.5	-1.9	0.4	-0.2	0.2	-0.2	-1.2	-1.6	-1.8	-0.0
Emphysema/chronic bronchitis	1.0	1.2	3.5	1.2	-1.9	-0.2	1.0	-0.2	0.1	1.3	1.2	-1.1
Medication: Blood pressure	1.0	1.8	3.8	-0.2	0.2	-1.7	-1.9	-1.6	-1.2	-2.0	-0.7	-1.1
Alcohol intake frequency.	1.0	2.3	9.4	-1.2	-3.1	-1.7	-1.2	-1.8	-0.4	-0.5	-1.0	-0.9
Age at last live birth	1.0	1.4	4.1	0.8	0.6	1.5	0.9	1.7	0.9	0.9	2.0	0.1
Average weekly champagne plus white wine intake	1.0	1.3	3.1	-1.4	0.8	0.2	-1.0	0.2	1.6	-0.7	-1.4	1.8
Depression (Nagel 2018)	0.9	1.4	7.1	2.7	0.3	0.4	1.3	0.3	0.1	0.8	1.6	-0.4
Frequency of depressed mood in last 2 weeks	0.9	1.3	3.9	1.8	-0.1	0.4	1.0	0.3	-0.9	1.1	2.0	-1.1
Hearing difficulty/problems: Yes	0.9	1.4	3.4	1.6	1.9	0.9	1.0	0.9	0.6	-0.6	1.8	-0.2
Sitting height	0.9	6.5	15.9	-2.7	-4.0	-2.1	-2.8	-2.1	-2.7	-1.5	-0.6	-3.0
Body mass index (BMI)	0.9	3.9	14.0	-1.5	-0.2	0.3	-2.0	0.3	2.8	1.1	-2.5	3.7
Allergy	0.9	2.0	6.5	-1.5	-1.8	-0.5	-0.3	-0.5	-2.5	-0.5	-0.7	-2.3
Breastfed as a baby	0.9	1.1	3.2	1.0	-0.2	1.1	0.6	1.1	0.5	1.8	1.5	0.1
Medication: Seretide 50 evohaler	0.9	1.1	4.7	2.2	0.5	0.0	0.7	0.0	-0.3	0.3	1.9	-0.8
Chest pain or discomfort	0.9	1.3	3.8	1.1	0.9	0.9	1.5	0.9	2.0	0.2	0.9	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	4.4	-2.1	-1.8	0.2	-1.0	0.3	-1.9	-1.5	-0.1	-1.3
Osteoarthritis (self-reported)	0.9	1.2	6.3	-0.5	0.2	-0.5	-2.5	-0.6	1.3	-0.4	-0.8	1.1
Wears glasses or contact lenses	0.9	1.0	4.6	0.6	0.6	0.6	-0.1	0.5	2.1	0.5	-0.8	1.6
Financial situation satisfaction	0.9	1.1	4.1	-0.0	-0.4	-0.3	-0.6	-0.3	-1.6	-2.0	0.5	-1.4
Reaction Time	0.8	1.6	5.9	1.4	0.9	0.6	0.8	0.5	1.4	2.4	1.1	1.1
Breast Cancer	0.8	2.0	6.9	-1.5	-1.3	-0.9	-2.6	-1.0	-1.4	-1.5	-0.1	-1.0
BMI	0.8	4.4	14.1	-1.0	0.2	1.6	-0.5	1.6	3.0	2.7	-1.6	3.8
Average weekly spirits intake	0.8	1.0	2.4	-0.6	0.1	1.5	0.8	1.5	0.8	0.9	0.6	1.3
Trunk fat mass	0.8	3.4	11.8	-1.3	0.9	1.9	-0.3	1.9	2.1	1.0	-1.8	3.4
Financial difficulties in last 2 years	0.8	1.0	2.5	-1.0	0.1	-0.7	-1.4	-0.7	0.7	-1.6	-1.4	0.6
Alcohol intake versus 10 years previously	0.8	1.2	3.0	-1.2	-1.0	-0.4	-1.7	-0.5	-1.7	0.2	1.0	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	5.1	0.2	0.4	1.0	-0.3	1.0	0.4	-0.8	-1.0	2.3
Loud music exposure frequency	0.8	0.9	3.9	-0.8	-0.1	0.3	-0.6	0.4	1.6	-0.0	-0.8	2.0
Headache pain in last month	0.8	1.3	4.9	1.2	0.8	0.3	0.3	0.2	2.2	0.7	-0.2	2.1
Worry too long after embarrassment	0.8	1.4	4.0	2.0	0.4	-0.5	1.7	-0.6	0.0	1.9	0.5	-0.8
Shortness of breath walking on level ground	0.8	1.0	3.5	0.2	1.2	0.7	-0.8	0.6	1.5	-0.2	-0.5	1.9
Whole body fat mass	0.8	3.2	11.0	-1.4	0.7	1.6	-0.5	1.7	2.1	1.2	-1.9	3.3
Leg fat mass (right)	0.8	3.0	11.1	-1.6	0.1	1.3	-0.9	1.3	1.9	1.0	-2.1	3.3
Pulse rate, automated reading	0.8	2.7	9.6	0.5	2.2	-0.4	0.9	-0.4	1.9	-0.1	-3.1	2.1
Smoking status: Previous	0.8	1.2	4.1	-0.6	-0.3	-1.1	-0.2	-1.2	-1.2	-1.6	-0.3	-2.0
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.7	-0.2	-1.3	-0.9	-0.5	-0.9	-1.4	-1.6	-0.4	-0.9
Arm fat mass (left)	0.8	3.2	10.9	-1.6	0.1	0.6	-1.4	0.7	2.2	0.6	-2.6	3.3
Tinnitus: Yes, now most or all of the time	0.8	1.0	3.0	0.6	-0.1	-0.5	-0.9	-0.4	-1.3	-0.9	1.7	-1.3
Unable to work because of sickness or disability	0.8	1.1	2.7	0.0	-1.4	-1.0	-0.9	-1.0	-1.7	-0.9	-0.2	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.9	-1.3	0.2	-1.2	-1.4	-1.3	-0.4	-1.4	-0.7	-0.5
Prostate Cancer	0.7	0.9	1.4	-0.8	-1.2	-0.9	-0.5	-1.0	-1.2	-1.1	-0.8	-1.1
Coronary Artery Disease (CAD)	0.7	0.8	3.0	0.7	0.4	0.4	-0.4	0.5	1.6	-0.2	-0.8	1.7
HbA1C	0.7	0.8	1.4	0.4	0.4	1.2	0.9	1.1	0.9	1.2	0.7	0.6
Heel T-Score	0.7	5.3	12.6	2.2	2.7	2.9	3.5	3.0	0.2	0.1	-1.1	2.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	4.0	1.0	0.4	0.7	1.0	0.7	0.2	1.1	2.0	-0.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.4	-0.7	-0.5	-0.2	-0.3	-0.2	-1.6	-1.4	0.4	-1.2
High blood pressure (mother)	0.7	1.0	1.8	-1.4	-1.0	-1.0	-1.1	-1.1	-0.7	-1.0	-0.1	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	5.5	2.3	0.4	0.2	1.0	0.2	1.0	0.6	1.2	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.7	0.7	1.9	1.1	1.7	1.1	0.8	1.0	-1.0	1.8
Medication: Ramipril	0.7	0.9	1.9	-0.6	-1.4	-1.4	-0.6	-1.4	0.9	-0.1	-0.7	-0.5
Arm fat mass (right)	0.7	2.9	10.4	-1.5	-0.2	0.6	-1.2	0.7	2.0	0.6	-2.5	3.2
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.2	0.7	1.1	0.9	0.3	0.8	1.5	-0.8	-0.2	1.3
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.1	0.1	-0.7	-0.8	0.1	-0.8	-0.9	-1.7	-0.4	-1.3
Number of full brothers	0.7	0.9	2.8	1.2	0.5	1.0	-0.2	1.0	0.7	1.0	1.7	0.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	3.5	-0.5	-1.9	-1.3	-0.0	-1.2	-0.2	0.6	-0.5	-0.7
Medication: Aspirin	0.7	1.0	2.2	-1.0	-1.5	-1.2	-0.4	-1.2	0.3	0.8	-1.3	0.0
Guilty feelings	0.7	1.0	5.0	2.2	1.4	-0.2	1.1	-0.3	0.4	0.1	0.7	0.1
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.6	1.0	0.1	-0.0	0.8	-0.0	0.2	-0.2	1.9	-1.5
Ever depressed for a whole week	0.7	0.9	2.9	0.8	-1.7	-0.7	0.3	-0.7	-1.0	-0.8	-0.4	-1.3
Leg fat mass (left)	0.7	2.6	9.4	-1.5	0.1	1.1	-1.0	1.2	1.8	0.9	-2.1	3.1
Fasting Glucose	0.6	0.8	3.9	-1.5	-2.0	-0.2	-0.5	-0.1	0.2	0.6	0.3	0.1
Rheumatoid Arthritis	0.6	0.9	1.7	0.7	1.3	0.9	1.3	0.8	0.4	1.2	1.0	-0.1
Past tobacco smoking	0.6	1.1	4.6	0.3	0.3	1.0	-0.2	1.0	1.0	1.5	0.4	2.1
Illnesses of siblings	0.6	0.9	1.8	0.0	-0.6	0.5	0.7	0.5	1.2	1.3	-1.1	1.3
Hip circumference	0.6	2.5	8.9	-1.4	0.1	1.0	-1.2	1.0	1.9	0.9	-1.9	3.0
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	6.7	-1.3	-2.6	1.4	-0.3	1.5	0.2	0.7	1.9	-0.3
Medication: Lansoprazole	0.6	0.7	2.2	-0.7	0.2	-0.5	-1.1	-0.6	-0.9	-0.7	-1.5	-0.4
Standing height	0.6	5.8	14.5	-2.0	-2.8	-1.0	-1.4	-0.9	-3.5	-3.0	0.6	-3.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	3.4	0.2	1.8	0.5	-0.2	0.5	1.2	-0.7	-0.6	0.6
Blood clot in the leg (DVT)	0.6	0.7	1.5	-1.2	0.3	-0.9	-1.1	-0.9	-0.1	-1.1	-1.0	-0.1
Medication: Amlodipine	0.6	0.8	2.0	0.1	0.4	-0.8	-0.9	-0.8	-1.1	-1.0	0.5	-1.4
Comparative body size at age 10	0.6	1.6	3.6	-1.0	-0.7	0.6	-1.9	0.6	1.6	1.6	-0.1	1.9
Medication: Omeprazole	0.6	0.7	2.3	-1.5	-0.2	-0.4	-0.2	-0.5	0.5	-1.1	-1.2	0.8
Leg pain on walking	0.6	0.8	2.8	-0.6	-0.2	-0.4	-1.5	-0.4	0.7	-0.5	-0.6	1.7
Knee pain experienced in last month	0.6	0.9	2.8	-1.1	-0.6	-0.2	-1.4	-0.1	-0.5	-1.0	-1.7	0.7
Eye problems/disorders: Cataract	0.6	0.7	1.8	1.1	0.1	-0.1	0.9	-0.1	-1.1	0.1	0.8	-1.4
Illnesses of father: None of the above (group 1)	0.6	0.8	1.9	-0.6	1.1	-0.8	-0.7	-0.8	0.2	-1.3	-1.4	0.4
Hearing aid user	0.6	0.7	2.2	0.7	1.3	0.4	-0.0	0.3	1.5	-0.5	0.4	1.0
Medication: Blood pressure	0.6	1.1	3.2	-0.2	-1.0	-1.4	-0.6	-1.4	-1.0	-0.1	-0.3	-1.8
Average weekly beer plus cider intake	0.6	0.8	2.4	0.1	0.7	1.5	0.2	1.5	0.3	-0.8	-0.2	1.2
Fractured/broken bones in last 5 years	0.6	0.8	1.6	-0.6	-1.3	-0.4	-1.1	-0.3	-0.3	1.2	-1.1	1.0
Ovarian Cancer	0.5	0.6	1.1	0.6	-0.7	1.0	-0.2	1.1	0.4	1.1	0.8	0.6
Blood White Count	0.5	3.4	9.4	-1.1	-2.3	-1.5	0.7	-1.4	-2.9	-0.9	-0.9	-3.1
Height	0.5	9.7	20.1	-2.2	-3.8	-1.9	-2.3	-1.8	-4.1	-4.5	0.6	-4.3
Waist Hip Ratio (WHR)	0.5	2.2	7.3	1.6	-1.8	-1.2	1.2	-1.2	-1.4	-0.7	0.5	-2.7
Supplements: Zinc	0.5	0.5	2.6	1.6	0.7	-0.2	-0.5	-0.2	-0.1	-0.8	0.7	-0.4
Medication: Co-codamol	0.5	0.6	1.3	0.6	-1.1	-1.0	-0.7	-1.1	-0.2	-0.1	-0.9	-0.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.1	-0.7	-1.3	-0.2	-0.2	-0.2	0.6	1.5	0.5	-0.5
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.7	-0.7	0.2	0.2	0.0	0.2	0.6	0.8	-1.3	1.3
Medication: Simvastatin	0.5	0.8	4.2	-0.9	0.2	-0.8	-0.5	-0.9	-0.4	-0.0	-2.1	0.4
Weight	0.5	2.5	6.3	-2.3	-1.4	-0.2	-2.5	-0.2	1.0	-0.3	-2.2	1.8
Time employed in main current job	0.5	0.5	1.5	0.4	-0.2	-0.4	0.5	-0.4	-1.2	-1.0	0.5	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.0	1.7	-0.1	0.7	0.7	0.7	1.0	0.4	0.1	1.2
Peak expiratory flow (PEF)	0.5	1.2	4.8	-0.8	-2.2	0.6	-0.7	0.6	-1.1	-0.8	1.2	-1.1
Exposure to tobacco smoke outside home	0.5	0.7	2.9	-0.7	-0.7	-0.4	-1.7	-0.4	-0.7	-1.1	-0.6	-0.2
Medication for pain relief, constipation, heartburn	0.5	0.8	3.2	1.3	0.7	0.4	0.7	0.4	0.6	0.0	1.8	-0.7
Average weekly red wine intake	0.5	0.8	3.8	-1.9	0.4	0.4	-1.0	0.4	1.0	0.2	0.4	0.9
Ever had bowel cancer screening	0.5	0.5	2.0	-0.0	-0.1	-0.6	0.2	-0.6	-0.7	-1.0	0.7	-1.4
Asthma (self-reported)	0.5	0.9	2.5	1.4	1.0	0.7	0.0	0.7	1.2	-0.2	0.7	1.6
Age started oral contraceptive pill	0.5	0.6	1.7	1.3	-0.8	0.1	0.4	0.1	1.3	0.5	0.2	0.9
Cholesterol lowering medication	0.5	0.8	3.5	-0.7	-0.2	-1.0	-0.1	-1.0	0.6	0.7	-1.9	0.5
Pain experienced in last month	0.5	0.9	3.0	0.9	0.8	0.6	1.3	0.6	-0.0	0.8	1.7	-0.9
Heart disease (siblings)	0.5	0.6	1.3	0.2	0.2	-1.2	-0.8	-1.2	-0.6	-0.7	0.3	-1.0
Alzheimer’s Disease (in mother)	0.4	0.4	1.5	0.5	-0.9	0.4	1.2	0.4	0.0	-0.6	-0.7	0.5
Alzheimer’s Disease (in father)	0.4	0.5	2.1	0.1	-1.5	-0.5	-0.1	-0.4	-0.9	0.4	0.5	-0.8
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.7	-0.0	-1.7	-0.2	0.6	-0.4	0.2	0.6	-0.8	0.0
Lung FEV1/FVC ratio	0.4	2.0	5.0	-0.6	-1.0	2.2	0.7	2.2	0.3	1.2	2.2	0.2
Chronotype (morning person)	0.4	0.9	2.9	-0.2	1.1	0.6	-0.4	0.5	-1.0	-1.4	1.7	-0.5
Diabetes (mother)	0.4	0.5	1.7	1.1	0.1	0.6	1.3	0.5	0.2	0.7	0.6	-0.6
Taking other prescription medications	0.4	0.6	2.0	1.3	1.4	0.5	0.1	0.5	0.5	0.6	0.4	0.4
Qualifications: CSEs or equivalent	0.4	0.5	1.7	-0.7	-0.1	-0.4	-0.9	-0.4	-0.4	-1.0	-1.3	0.0
Supplements: Glucosamine	0.4	0.5	2.4	-0.3	-0.5	-0.3	-0.2	-0.3	-0.9	-1.6	0.9	-0.3
Chronic bronchitis/emphysema (father)	0.4	0.4	1.1	-0.3	-1.0	-0.7	-0.8	-0.7	-0.2	-0.6	-0.5	-0.6
Waist circumference	0.4	1.3	4.9	-1.0	-1.1	-0.6	-1.4	-0.6	0.9	-0.1	-2.2	1.1
Alcohol usually taken with meals	0.4	0.6	1.9	-1.1	0.6	0.5	-0.8	0.5	0.5	1.4	0.2	0.8
Forced vital capacity (FVC)	0.4	1.5	4.5	-1.5	-2.1	0.9	-0.4	1.0	-0.4	0.2	1.9	-1.1
Asthma	0.4	0.9	2.3	1.5	1.0	0.6	-0.3	0.5	1.1	-0.5	0.6	1.5
Illnesses of mother	0.4	0.5	1.5	-0.5	0.6	0.1	-0.9	0.1	-0.4	0.3	-1.1	1.2
Medication: Paracetamol	0.4	0.6	2.0	0.1	-0.4	-0.3	-1.0	-0.3	-1.4	-1.4	-0.4	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.0	0.2	-0.1	1.1	1.4	1.1	0.6	1.0	0.7	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.0	-0.0	-0.5	-1.0	0.9	-1.0	-1.0	-0.3	0.5	-1.7
Birth weight	0.4	0.9	4.1	-2.0	-0.7	-0.2	-0.6	-0.1	-0.3	-1.6	0.0	-0.3
Health satisfaction	0.4	0.6	2.2	-0.3	-0.3	-0.8	-0.7	-0.8	-0.5	-1.5	-0.6	-0.5
Friendships satisfaction	0.4	0.4	1.0	-0.7	-1.0	-0.2	0.5	-0.2	0.5	0.4	-0.9	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.3	-1.1	0.5	-0.1	-0.3	-0.1	-0.4	1.0	1.1	-0.7
High cholesterol (Self-reported)	0.4	0.6	2.0	1.0	1.4	0.4	-0.2	0.4	-0.0	0.3	-1.4	0.6
Medication: Lisinopril	0.4	0.5	2.5	-0.7	0.9	-0.3	-1.6	-0.3	-0.4	-0.5	-0.7	0.3
Illnesses of father: High blood pressure	0.4	0.5	1.3	0.3	0.7	0.9	0.9	0.8	-0.4	0.5	1.2	-0.2
Irritability	0.4	0.6	2.1	1.2	1.2	0.2	1.4	0.3	0.4	0.2	0.7	-0.1
Risk taking	0.4	0.6	1.1	-0.4	0.4	1.1	-0.7	1.1	-0.6	-1.0	0.6	0.6
Diastolic blood pressure, automated reading	0.4	1.3	5.1	-0.1	-0.2	-1.3	-0.5	-1.4	-2.2	-0.5	-0.1	-1.6
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.6	-1.3	0.0	0.1	-0.1	0.0	0.8	-0.3	-1.0	1.1
Depressed Affect (Nagel 2018)	0.3	0.7	2.4	1.5	-0.6	-1.0	0.7	-1.0	-0.0	0.0	0.2	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	0.8	-1.4	0.2	1.1	0.1	-0.2	-0.1	-0.5	0.4
Age at First Birth	0.3	0.5	1.5	-0.2	1.2	0.3	0.4	0.3	0.5	-0.1	-0.9	1.1
Blood Platelet Count	0.3	3.9	10.8	-0.8	3.3	2.4	0.8	2.4	1.5	-1.1	-1.6	2.4
Diabetes (father)	0.3	0.4	1.4	-0.5	-0.2	-0.6	-1.2	-0.7	-0.4	-0.6	0.3	-0.5
Stomach or abdominal pain in last month	0.3	0.4	1.3	-0.2	-0.1	1.0	-0.1	1.0	-0.1	0.6	1.1	0.2
Had menopause	0.3	0.4	1.1	0.4	-0.2	-0.6	0.3	-0.6	0.7	1.1	-0.4	0.9
Happiness	0.3	0.4	1.3	-0.5	-0.3	0.2	0.3	0.3	1.1	0.7	-0.2	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.9	1.0	0.7	-0.2	0.7	-0.2	-0.3	-0.3	0.6	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	5.0	-1.3	-2.2	0.6	-0.7	0.7	-0.0	-0.1	0.8	-0.2
Forced vital capacity (FVC), Best measure	0.3	1.0	4.2	-1.4	-2.1	0.2	-0.8	0.3	-0.6	-0.3	0.9	-0.8
Mean time to correctly identify matches	0.3	0.5	3.0	0.5	0.2	0.0	0.6	-0.0	0.4	1.7	0.9	0.4
Had major operations	0.3	0.4	0.8	0.3	0.9	0.6	0.4	0.6	0.8	-0.1	-0.2	0.9
Mood swings	0.3	0.5	1.2	0.6	-0.3	-1.1	-0.1	-1.1	-0.3	-0.3	-0.0	-1.1
Loneliness, isolation	0.3	0.4	1.6	1.3	-0.4	-0.0	1.0	-0.1	-0.5	0.5	-0.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.7	-0.1	-0.1	-0.3	-1.1	-0.2	0.3	-1.6	-0.2	0.3
Number of self-reported non-cancer illnesses	0.3	0.6	2.5	0.9	1.6	-0.5	-0.5	-0.5	-0.3	-1.1	0.1	-0.2
Medication: Bendroflumethiazide	0.3	0.4	1.0	-0.9	-0.2	0.1	-0.7	0.1	-0.7	-1.0	-0.4	-0.8
Medication: Atorvastatin	0.3	0.4	1.8	1.3	-0.2	-0.5	-0.5	-0.4	0.1	-0.5	0.0	-0.7
Ever smoked	0.3	0.5	2.1	-0.0	0.2	0.0	0.6	0.0	-0.9	-1.0	-0.3	-1.4
Commuting to job workplace: Cycle	0.3	0.4	0.8	0.4	0.8	-0.6	-0.5	-0.7	-0.3	0.9	0.4	-0.7
Crohns Disease (2017)	0.2	0.4	1.7	-1.1	0.2	-0.3	-1.3	-0.3	0.4	-0.9	0.1	-0.1
Triglycerides	0.2	0.4	2.2	-0.5	-1.5	0.2	0.0	0.2	0.0	0.1	0.8	-0.3
Blood Eosinophil Count	0.2	1.9	6.4	1.8	0.7	1.6	2.5	1.7	0.1	0.7	-0.2	0.6
Severe depression (siblings)	0.2	0.2	0.6	0.7	0.6	-0.5	0.3	-0.5	0.0	-0.8	-0.4	0.0
Fed-up feelings	0.2	0.4	1.0	1.0	0.3	0.1	1.0	0.1	0.9	0.9	-0.1	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.7	0.8	-0.6	-0.1	-0.1	-0.2	-0.4	-0.0	0.8	-0.5
Multivitamins +/- minerals	0.2	0.3	1.1	1.1	0.4	0.2	0.7	0.3	-0.3	0.1	0.6	-0.8
Pain all over the body in last month	0.2	0.2	0.8	-0.1	-0.9	-0.5	-0.4	-0.5	-0.2	0.5	-0.1	-0.5
Hair/balding pattern: Pattern 3	0.2	0.3	0.9	0.3	-0.2	-0.9	0.3	-0.9	0.8	-0.4	0.1	-0.2
Birth weight of first child	0.2	0.4	1.1	-0.0	-0.3	-0.9	-0.4	-0.8	0.5	-1.1	-0.9	-0.1
Gout (self-reported)	0.2	0.3	1.1	-0.2	0.5	0.1	0.2	0.1	1.0	0.8	0.4	0.4
Wheeze or whistling in the chest in last year	0.2	0.3	1.5	1.2	0.5	-0.1	-0.2	-0.2	0.7	0.1	0.7	0.3
Age at first live birth	0.2	0.4	1.3	-0.1	0.3	0.6	0.9	0.7	0.9	0.2	1.2	0.2
Neck or shoulder pain in last month	0.2	0.3	0.9	-0.6	-0.8	-0.2	-0.2	-0.2	-0.9	-0.6	-0.0	-0.3
Medication: Allopurinol	0.2	0.3	0.6	-0.7	-0.4	-0.7	-0.4	-0.7	-0.2	-0.4	0.3	-0.7
Heart disease (mother)	0.2	0.2	0.4	-0.5	0.4	-0.5	-0.2	-0.6	0.1	-0.3	0.4	-0.6
Family relationship satisfaction	0.2	0.2	1.9	0.2	-0.4	-0.1	1.4	-0.1	0.1	0.3	-0.0	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.0	0.6	0.6	-0.1	0.1	-0.1	-1.0	0.3	0.5	-0.3
Long-standing illness, disability or infirmity	0.2	0.3	1.1	0.6	0.2	0.1	0.4	0.1	0.7	-0.1	-0.5	1.1
Medication for cholesterol	0.2	0.3	1.2	0.3	0.8	0.5	0.1	0.4	0.4	-0.7	-0.3	1.1
Medication: Paracetamol	0.2	0.3	1.3	1.2	-0.1	0.5	-0.1	0.5	-0.6	-0.5	0.0	0.5
Alcohol drinker status: Never	0.2	0.2	0.9	-0.3	-0.8	0.2	-0.3	0.2	0.9	0.2	0.4	0.3
Crohns Disease (2012)	0.1	0.2	0.4	-0.5	-0.2	-0.3	-0.6	-0.4	-0.5	-0.5	0.0	-0.4
HDL Cholesterol	0.1	0.2	0.3	-0.6	0.3	0.2	-0.6	0.2	0.5	0.4	0.1	0.2
Neuroticism (2016)	0.1	0.2	0.5	0.3	0.1	-0.5	0.2	-0.5	0.4	0.6	-0.7	0.2
Blood Red Count	0.1	0.8	2.0	1.0	-0.4	-0.7	1.4	-0.7	-0.3	1.0	-1.0	-1.0
Lung FVC	0.1	0.7	3.3	-0.1	-0.3	0.5	0.2	0.6	1.0	1.3	1.8	0.1
Vitamin and mineral supplements	0.1	0.1	0.3	0.0	-0.1	0.2	0.4	0.2	0.6	0.1	-0.4	0.4
Medication: Cholesterol lowering	0.1	0.1	0.5	-0.1	-0.3	-0.3	-0.7	-0.3	-0.3	0.0	-0.7	-0.2
Eye problems/disorders: None of the above	0.1	0.1	0.6	0.0	-0.3	-0.1	-0.1	-0.1	-0.6	0.8	0.0	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.6	0.1	0.5	0.5	0.0	0.5	-0.4	-0.8	0.2	-0.0
Illnesses of siblings: Diabetes	0.1	0.2	0.5	0.6	0.1	0.1	0.3	0.2	-0.6	-0.7	0.2	-0.0
Miserableness	0.1	0.3	1.3	1.1	-0.1	-0.3	0.4	-0.3	0.2	0.6	-0.2	-0.5
Hair Pigment	0.0	0.5	1.4	-0.7	-0.2	0.7	-0.1	0.8	-0.8	0.8	1.2	-0.6
Tanning	0.0	0.5	1.4	0.3	-0.4	0.2	0.6	0.1	1.2	0.7	-0.7	1.0

Hub : Genes

BTRC

Models

Trait associations