Hub : Genes

C10orf18

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0940 0.0300 0.00012 0.031 0.042 0.031 0.048 0.047 0.0001 6.6e-06 9.6e-05 1.6e-06 1.9e-06
2 TCGA Breast Invasive Carcinoma 0.0198 0.0093 0.00010 0.007 0.017 0.012 NA 0.010 0.0110 1.3e-04 1.1e-03 NA 3.1e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.3 0.4 0.7 -0.4 0.8
Bipolar Disorder or Schizophrenia 0.8 1.9 2.9 -0.9 1.7
Depressed Affect (Nagel 2018) 1.1 2.3 3.3 -1.8 1.1
Depression (Nagel 2018) 0.4 0.6 0.9 -0.9 0.6
Intelligence (Savage-Jansen 2018) 0.6 1.9 3.4 0.6 -1.8
Neuroticism (Nagel 2018) 1.2 2.9 4.5 -2.1 1.1
Schizophrenia (2018) 0.8 1.7 2.5 -1.0 1.6
Schizophrenia vs Biploar Disorder 0.1 0.1 0.2 0.4 0.1
Worry (Nagel 2018) 0.3 0.7 0.9 -0.9 0.7
Alzheimer’s Disease (in mother) 0.5 0.6 0.9 -1.0 -0.5
Alzheimer’s Disease (in father) 0.7 0.7 1.4 -0.2 1.2
Alzheimer’s Disease (including proxy) 0.3 0.4 0.7 -0.8 0.3
Crohns Disease (2017) 0.7 1.6 3.2 -1.8 -0.1
Irritable Bowel Disease (IBD) 0.6 1.4 2.9 -1.7 0.1
Ulcerative Colitis (UC) 0.0 0.1 0.2 -0.4 0.1
Major Depression (MDD) 0.6 0.8 1.2 -0.5 -1.1
Reaction Time 0.4 0.7 1.1 1.0 0.6
Verbal and Numeric Reasoning (VNR) 0.1 0.3 0.5 -0.3 -0.7
Breast Cancer 1.9 4.7 9.1 0.5 -3.0
Ovarian Cancer 0.1 0.1 0.1 -0.3 0.3
Prostate Cancer 0.9 1.2 2.0 -0.7 1.4
Age at First Birth 0.1 0.1 0.1 -0.3 -0.3
Bipolar Disorder (2011) 1.6 1.6 2.0 -1.1 -1.4
Body Mass Index (BMI) (2010) 0.1 0.1 0.2 0.5 0.1
Coronary Artery Disease (CAD) 1.3 1.6 2.0 -1.1 -1.4
Crohns Disease (2012) 0.5 0.7 1.4 -1.2 -0.3
Mean Putamen Volume 0.9 1.0 1.4 -0.8 1.2
Fasting Glucose 1.6 2.0 2.4 -1.6 1.2
HbA1C 0.9 1.0 1.7 0.5 -1.3
HDL Cholesterol 0.9 1.6 2.8 -0.6 1.7
LDL Cholesterol 1.6 2.5 4.0 1.0 -2.0
Lupus 0.5 0.7 1.2 0.4 1.1
Neuroticism (2016) 1.2 1.7 2.3 -1.1 1.5
Primary Biliary Cirrhosis 0.9 1.2 2.3 -1.5 -0.4
Rheumatoid Arthritis 0.4 0.6 1.0 -0.5 -1.0
Schizophrenia (2014) 1.4 3.0 4.8 -1.1 2.2
Triglycerides 1.0 1.7 1.9 1.4 -1.2
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.1 0.0 0.3
Ulcerative Colitis 0.3 0.4 0.5 -0.6 -0.7
Blood Eosinophil Count 0.3 2.3 3.9 -2.0 0.9
Blood Platelet Count 0.2 2.6 4.4 2.1 0.9
Blood Red Count 0.0 0.5 0.6 0.6 -0.8
Blood White Count 0.2 1.3 2.4 -0.5 1.6
Heel T-Score 0.2 1.6 2.1 -1.0 -1.4
BMI 0.2 0.9 1.2 -0.7 -1.1
Height 0.9 17.9 22.0 3.7 -4.7
Waist Hip Ratio (WHR) 0.2 0.9 1.6 0.5 -1.3
Systolic Blood Pressure 0.2 1.2 2.0 -0.6 1.4
Smoking Status 1.5 3.6 6.9 -2.6 0.6
Allergy or Eczema 2.4 6.4 8.6 -2.9 2.1
Cardiovascular Disease 0.0 0.1 0.1 0.2 -0.3
Hypothyroidism (self reported) 2.3 5.2 9.3 1.1 -3.0
Respiratory disease 1.8 4.0 4.1 -2.0 2.0
Type 2 Diabetes (T2D) (2018) 0.2 0.4 0.8 -0.1 -0.9
Lung FEV1/FVC ratio 0.1 0.3 0.4 -0.5 0.6
Lung FVC 0.4 2.2 2.4 1.6 1.4
Neuroticism 2.7 6.4 8.2 -2.9 2.1
Chronotype (morning person) 0.7 1.7 2.6 1.6 0.9
Hair Pigment 0.1 3.4 3.6 1.9 -1.8
Tanning 2.7 33.3 38.9 -5.3 6.2
Hand grip strength (left) 2.5 6.6 12.9 3.6 -0.5
Number of treatments/medications taken 0.5 0.9 1.2 -1.1 0.8
Average weekly spirits intake 1.0 1.3 1.3 -1.2 1.1
Sensitivity / hurt feelings 5.6 9.5 11.3 -3.4 2.8
Frequency of depressed mood in last 2 weeks 0.6 0.9 1.6 -1.2 0.5
Hearing difficulty/problems: Yes 0.0 0.1 0.1 0.3 0.2
Relative age of first facial hair 0.2 0.5 0.9 -0.1 -1.0
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 1.1 -1.1 -0.9
Ever used hormone-replacement therapy (HRT) 0.4 0.5 0.8 0.9 -0.5
Ever had hysterectomy (womb removed) 1.3 1.5 2.8 -1.7 0.4
Systolic blood pressure, automated reading 0.0 0.0 0.0 -0.1 0.0
Eye problems/disorders: Diabetes related eye disease 3.6 4.0 4.0 2.0 -2.0
Angina 0.1 0.2 0.3 0.0 0.6
Medication for hormone replacement therapy 1.6 1.8 3.5 0.3 -1.9
Vitamin and mineral supplements 1.9 2.6 3.1 -1.8 1.4
Supplements: Zinc 0.2 0.2 0.2 -0.5 -0.4
Medication: Co-codamol 0.0 0.0 0.1 0.3 0.1
Medication: Metformin 0.0 0.0 0.0 0.2 -0.2
Diabetes (father) 0.4 0.6 0.8 -0.5 -0.9
Diabetes (mother) 0.0 0.0 0.0 0.0 0.1
Severe depression (siblings) 0.3 0.4 0.5 -0.7 -0.5
Pack years adult smoking proportion 0.4 0.6 1.1 -1.1 -0.0
Impedance of leg (right) 0.6 2.7 3.9 1.2 -2.0
Leg fat-free mass (left) 0.1 0.8 1.4 0.4 -1.2
Trunk fat percentage 0.8 3.3 5.4 1.1 -2.3
Hand grip strength (right) 1.9 5.2 10.3 3.2 0.1
Townsend deprivation index at recruitment 0.5 0.7 1.3 -1.1 0.3
Current tobacco smoking 1.7 2.8 5.5 -2.3 0.4
Average weekly fortified wine intake 0.3 0.4 0.8 -0.9 -0.0
Maternal smoking around birth 0.6 0.9 1.4 -1.2 0.6
Fed-up feelings 0.9 1.6 3.0 -1.7 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.6 4.1 -2.0 1.1
Relative age voice broke 0.9 1.3 2.0 1.4 -0.8
Taking other prescription medications 1.1 1.7 2.5 -1.6 1.0
Age when periods started (menarche) 0.0 0.1 0.1 -0.3 0.4
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 1.6 -0.8 1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.4 -0.1 -1.2
Tinnitus: Yes, but not now, but have in the past 2.3 2.4 3.7 -1.1 1.9
Qualifications: CSEs or equivalent 0.0 0.0 0.0 0.1 0.2
Serious illness, injury or assault to yourself 0.3 0.3 0.5 -0.7 -0.4
High blood pressure 0.1 0.2 0.3 0.2 -0.5
Hayfever, allergic rhinitis or eczema 1.5 3.2 3.6 -1.7 1.9
Multivitamins +/- minerals 3.2 4.1 5.0 2.2 -1.8
Stomach or abdominal pain in last month 0.1 0.1 0.1 0.1 0.4
Supplements: Glucosamine 0.1 0.1 0.2 0.5 -0.2
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.5 -0.4 1.2
Medication: Atenolol 0.8 1.0 1.1 -1.1 1.0
Medication: Levothyroxine sodium 1.1 1.9 2.3 1.2 -1.5
Sitting height 0.2 1.6 2.3 0.9 -1.5
Chronic bronchitis/emphysema (father) 0.7 0.8 1.5 0.3 -1.2
High blood pressure (mother) 0.6 0.9 1.6 0.3 -1.3
Body mass index (BMI) 0.1 0.3 0.6 -0.7 -0.0
Impedance of leg (left) 1.3 6.1 8.3 2.0 -2.9
Leg predicted mass (left) 0.1 0.7 1.3 0.3 -1.2
Trunk fat mass 0.8 3.4 5.8 1.1 -2.4
Waist circumference 0.2 0.6 0.8 -0.7 -0.9
Number of incorrect matches in round 1.7 2.8 3.8 -2.0 1.3
Past tobacco smoking 0.2 0.3 0.5 0.5 0.7
Alcohol usually taken with meals 0.9 1.5 2.1 0.9 1.4
Nervous feelings 0.1 0.2 0.2 -0.4 -0.4
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.2 4.3 -2.1 0.2
Hearing difficulty/problems with background noise 0.6 1.0 1.4 -1.2 -0.8
Hair/balding pattern: Pattern 2 0.8 1.0 1.5 1.2 0.7
Had menopause 0.0 0.0 0.1 -0.3 0.1
Had other major operations 0.3 0.4 0.8 -0.9 0.1
Forced vital capacity (FVC) 1.7 6.4 12.0 3.5 -0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 1.6 0.2 -1.3
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.4 0.7 0.6
Qualifications: None of the above 0.2 0.5 1.0 -1.0 0.2
Financial difficulties in last 2 years 3.3 4.5 7.9 -2.8 1.0
Mouth/teeth dental problems 0.7 1.1 2.0 1.4 0.4
Heart attack 0.1 0.1 0.2 0.1 -0.5
Allergy 2.7 6.3 8.0 2.8 -2.1
Pain all over the body in last month 0.4 0.5 0.7 -0.9 0.4
Diabetes (self-reported) 0.3 0.4 0.8 -0.9 -0.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.4 0.6 -0.6
Medication: Ramipril 0.3 0.4 0.9 0.9 0.2
Medication: Simvastatin 1.0 1.4 2.2 -0.8 -1.5
Fluid intelligence score 0.0 0.0 0.1 0.1 0.3
Illnesses of siblings 0.1 0.1 0.1 0.2 0.4
Neuroticism score 2.2 4.7 7.1 -2.7 1.5
Weight 0.2 1.1 2.2 0.3 -1.5
Impedance of arm (right) 1.3 6.2 7.0 2.6 -2.3
Arm fat percentage (right) 0.1 0.5 1.0 0.3 -1.0
Trunk fat-free mass 0.0 0.1 0.2 -0.2 -0.4
Hip circumference 0.1 0.4 0.7 -0.3 -0.8
Time employed in main current job 1.3 1.5 1.9 1.1 -1.4
Alcohol intake versus 10 years previously 1.6 2.3 3.0 1.3 -1.7
Father’s age at death 0.6 0.7 1.2 -1.1 0.6
Worrier / anxious feelings 0.3 0.6 1.2 -1.1 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.9 3.1 3.1 -1.8 -1.7
Falls in the last year 2.6 3.5 5.2 -2.3 1.4
Hair/balding pattern: Pattern 3 0.2 0.3 0.6 0.8 -0.2
Number of live births 1.8 2.6 4.8 -2.2 0.7
Forced expiratory volume in 1-second (FEV1) 1.5 5.1 10.1 3.2 -0.4
Pulse rate 0.8 1.4 2.6 1.6 0.4
Happiness 0.7 0.9 1.7 -0.3 1.3
Noisy workplace 0.5 0.6 0.9 -1.0 -0.6
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.1 -0.3 -0.0
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.1 -0.1 0.4
Mouth/teeth dental problems: Dentures 1.2 2.1 3.6 0.7 -1.9
Asthma 5.3 10.4 11.6 -3.4 3.0
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 0.3 0.0 0.6
Medication: Cholesterol lowering 0.4 0.7 1.4 -1.2 -0.2
Depression (self-reported) 0.8 0.9 1.4 -0.7 -1.2
Medication: Lansoprazole 0.6 0.6 0.8 -0.9 -0.7
Prospective memory result 0.0 0.0 0.0 -0.1 -0.1
Lung cancer (father) 0.6 0.7 1.0 1.0 -0.7
Illnesses of mother 1.3 1.7 3.2 -0.3 1.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.2 9.8 3.1 -0.8
Pulse wave Arterial Stiffness index 0.2 0.3 0.4 0.3 -0.7
Impedance of arm (left) 1.1 5.0 6.0 2.5 -2.0
Arm fat mass (right) 0.2 0.7 1.4 0.2 -1.2
Trunk predicted mass 0.0 0.1 0.2 -0.2 -0.4
Standing height 0.8 7.9 10.2 2.4 -3.2
Length of working week for main job 0.2 0.2 0.3 -0.2 -0.5
Exposure to tobacco smoke at home 0.1 0.2 0.2 -0.5 -0.3
Breastfed as a baby 0.5 0.6 1.0 0.3 1.0
Tense / ‘highly strung’ 0.6 1.0 1.5 -0.7 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 4.0 6.1 10.1 -3.2 1.4
Hair/balding pattern: Pattern 4 1.4 3.5 6.5 -2.5 0.7
Birth weight of first child 0.9 1.6 1.8 -1.2 1.3
Peak expiratory flow (PEF) 1.1 2.6 5.2 2.3 -0.2
Pulse wave reflection index 1.2 1.5 2.9 -1.7 0.3
Ever highly irritable/argumentative for 2 days 0.6 0.8 0.8 -0.8 0.9
Loud music exposure frequency 0.2 0.2 0.3 0.6 -0.3
Qualifications: O levels/GCSEs or equivalent 0.1 0.2 0.4 0.2 -0.6
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.1 -1.0 -0.1
Blood clot in the leg (DVT) 0.9 1.2 2.4 -1.5 -0.2
Medication: Paracetamol 0.1 0.2 0.4 -0.3 -0.6
Headache pain in last month 2.9 5.0 6.4 2.5 -1.9
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 2.7 1.6 0.3
Glaucoma (self-reported) 0.0 0.0 0.0 0.1 -0.1
Gout (self-reported) 0.1 0.2 0.2 0.4 0.4
Hypothyroidism/myxoedema (self-reported) 2.1 4.2 5.1 1.8 -2.2
Medication: Amlodipine 0.3 0.5 0.5 -0.6 -0.7
Medication: Ventolin 100micrograms inhaler 0.8 1.1 2.1 -1.4 0.0
Birth weight 0.2 0.4 0.5 0.4 0.7
Chronic bronchitis/emphysema (mother) 0.5 0.6 0.6 -0.8 0.8
High blood pressure (siblings) 0.0 0.0 0.1 0.2 -0.0
Forced vital capacity (FVC), Best measure 2.0 7.1 13.0 3.6 -1.1
Body fat percentage 0.6 2.3 4.0 0.8 -2.0
Leg fat percentage (right) 0.1 0.4 0.8 -0.1 -0.9
Arm fat-free mass (right) 0.1 0.3 0.3 -0.6 -0.5
Exposure to tobacco smoke outside home 0.4 0.5 0.9 -0.5 0.9
Comparative body size at age 10 0.0 0.1 0.1 0.4 0.2
Number of full brothers 0.5 0.6 1.2 -1.1 -0.0
Worry too long after embarrassment 0.6 1.0 1.7 -1.3 0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 3.7 4.7 6.8 -2.6 1.6
Wheeze or whistling in the chest in last year 4.6 8.2 11.3 -3.4 2.3
Number of children fathered 1.5 1.7 3.3 0.1 1.8
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 0.6 -0.2 0.8
Age at first live birth 0.2 0.4 0.6 0.7 0.5
Pulse wave peak to peak time 0.1 0.1 0.2 -0.1 0.5
Health satisfaction 0.7 0.8 0.9 -0.9 0.9
Shortness of breath walking on level ground 0.7 0.8 0.9 -0.9 -0.9
Qualifications: College or University degree 0.1 0.4 0.4 0.6 0.6
Eye problems/disorders: None of the above 1.8 2.1 3.3 -1.8 1.0
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.5 0.1 0.7
Emphysema/chronic bronchitis 0.3 0.4 0.5 -0.4 -0.7
Medication for pain relief, constipation, heartburn 1.0 1.6 2.1 1.4 -1.1
Neck or shoulder pain in last month 0.5 0.7 1.3 -1.1 -0.4
Medication: Blood pressure 0.7 1.2 1.9 -1.4 -0.7
Angina (self-reported) 0.1 0.1 0.3 0.2 0.5
Migraine (self-reported) 2.3 2.8 4.1 1.2 -2.0
Medication: Ibuprofen 0.1 0.1 0.3 0.5 -0.1
Medication: Allopurinol 0.0 0.1 0.1 -0.3 0.1
Medication: Omeprazole 0.6 0.7 1.1 -1.1 -0.5
Medication: Seretide 50 evohaler 0.8 0.9 1.3 -1.2 0.7
Mean time to correctly identify matches 0.5 1.0 1.7 1.3 0.6
Heart disease (mother) 0.0 0.0 0.0 0.0 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.7 1.2 -1.1 0.4
Whole body fat mass 0.6 2.3 4.3 0.6 -2.1
Leg fat mass (right) 0.4 1.6 3.2 0.1 -1.8
Arm predicted mass (right) 0.1 0.4 0.5 -0.6 -0.7
Pulse rate, automated reading 1.9 6.3 9.3 3.1 -1.8
Alcohol intake frequency. 3.7 8.6 12.1 2.2 -3.5
Comparative height size at age 10 0.2 0.9 1.1 0.9 -1.1
Number of full sisters 0.5 0.6 1.1 0.1 1.1
Suffer from ‘nerves’ 0.8 1.3 2.3 -1.5 0.6
Overall health rating 0.7 1.5 2.9 -1.7 0.2
Chest pain or discomfort 0.4 0.5 0.8 0.9 -0.5
Had major operations 1.2 1.4 2.7 -0.4 1.6
Age at last live birth 0.2 0.2 0.4 0.6 0.2
Family relationship satisfaction 1.2 1.4 1.5 -1.2 1.2
Leg pain on walking 0.0 0.0 0.1 -0.1 0.2
Qualifications: NVQ or HND or HNC or equivalent 2.7 3.3 3.9 -2.0 1.6
Commuting to job workplace: Car/motor vehicle 1.2 1.4 2.2 -0.8 -1.5
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 2.6 1.6 -0.7
Medication: Aspirin 0.2 0.2 0.3 -0.5 0.4
Supplements: Vitamin C 0.7 0.8 1.0 1.0 -0.8
Knee pain experienced in last month 0.6 1.0 1.7 -1.3 -0.6
Hypertension (Self-reported) 0.0 0.1 0.1 -0.0 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.4 -0.7 0.0
Illnesses of father: Heart disease 1.3 1.8 3.4 0.5 -1.9
Illnesses of siblings: Diabetes 0.5 0.6 1.2 -0.3 -1.1
Smoking status: Previous 0.1 0.2 0.3 -0.0 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.0 0.0 0.0 0.2 -0.1
Whole body fat-free mass 0.1 0.4 0.8 0.1 -0.9
Leg fat-free mass (right) 0.2 1.2 2.0 0.7 -1.4
Arm fat percentage (left) 0.1 0.4 0.8 0.1 -0.9
Average weekly red wine intake 1.4 2.0 3.5 0.8 1.9
Handedness (chirality/laterality): Left-handed 1.9 2.3 3.5 1.1 -1.9
Mood swings 0.7 1.3 2.3 -1.5 0.5
Loneliness, isolation 6.0 8.3 10.3 -3.2 2.5
Long-standing illness, disability or infirmity 2.2 3.3 4.9 -2.2 1.3
Ever had bowel cancer screening 3.0 3.5 7.1 -2.7 0.2
Diabetes diagnosed by doctor 0.5 0.7 1.3 -1.1 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 2.5 -1.6 0.4
Friendships satisfaction 3.6 4.5 7.7 -1.1 2.8
Qualifications: nursing, teaching 0.1 0.1 0.1 -0.3 -0.4
Commuting to job workplace: Walk 2.0 2.2 3.3 1.8 -1.0
Eye problems/disorders: Cataract 0.8 0.9 1.7 1.3 -0.4
Mouth/teeth dental problems: Mouth ulcers 2.3 3.6 5.2 -2.3 1.4
Medication for cholesterol 0.1 0.1 0.2 -0.2 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 1.8 -1.3 0.0
Back pain experienced in last month 2.1 3.1 4.7 2.2 -1.2
Mineral and other dietary supplements 2.7 3.6 3.7 -1.9 1.9
Breast cancer (self-reported) 6.5 7.8 9.4 -3.1 2.5
Asthma (self-reported) 4.9 9.7 10.7 -3.3 2.9
Osteoporosis (self-reported) 0.2 0.3 0.4 0.6 0.3
Osteoarthritis (self-reported) 1.6 2.1 3.5 -1.9 0.9
Medication: Aspirin 0.2 0.2 0.4 -0.6 0.2
Medication: Gliclazide 1.1 1.2 2.5 0.1 -1.6
Illnesses of father: None of the above (group 1) 1.2 1.5 3.0 -0.1 1.7
Smoking status: Current 1.6 2.5 4.8 -2.2 0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.6 1.7 1.3 1.2
Whole body water mass 0.1 0.4 0.7 0.0 -0.9
Leg predicted mass (right) 0.2 1.1 1.9 0.6 -1.4
Arm fat mass (left) 0.2 0.7 1.3 0.1 -1.1
Number of self-reported non-cancer illnesses 0.3 0.5 0.7 -0.9 -0.4
Average weekly champagne plus white wine intake 2.7 3.7 6.2 -1.1 2.5
Miserableness 0.7 1.2 2.3 -1.5 0.3
Guilty feelings 3.4 5.1 9.3 -3.0 0.9
Wears glasses or contact lenses 0.6 0.6 1.3 0.1 1.1
Ever taken oral contraceptive pill 0.2 0.2 0.3 -0.0 -0.6
Hearing aid user 0.5 0.6 1.1 0.1 -1.0
Mother’s age at death 0.2 0.2 0.4 0.6 -0.2
Financial situation satisfaction 1.3 1.6 1.7 -1.3 1.2
Tinnitus: Yes, now most or all of the time 1.4 1.7 3.3 0.3 -1.8
Commuting to job workplace: Public transport 1.9 2.3 2.7 1.4 1.6
Eye problems/disorders: Glaucoma 0.2 0.2 0.4 0.2 -0.6
Medication: Blood pressure 0.4 0.8 1.6 -0.2 1.3
Pain type(s) experienced in last month: Hip pain 0.3 0.4 0.4 0.6 -0.6
Supplements: Fish oil (including cod liver oil) 2.2 2.9 3.3 1.8 -1.6
High cholesterol (Self-reported) 0.2 0.4 0.5 -0.5 -0.7
Medication: Bendroflumethiazide 0.3 0.5 0.7 0.9 -0.5
Medication: Paracetamol 0.3 0.4 0.8 0.3 -0.9
Medication: Lisinopril 0.7 0.9 1.0 -0.9 1.0
Medication: Atorvastatin 0.0 0.1 0.1 -0.1 0.3
Illnesses of father: High blood pressure 0.1 0.1 0.2 -0.3 -0.4
Alcohol drinker status: Never 0.2 0.2 0.2 0.5 -0.4
Ever smoked 0.3 0.5 0.8 -0.9 -0.4
Basal metabolic rate 0.1 0.7 1.3 0.1 -1.2
Leg fat percentage (left) 0.3 1.2 2.1 0.5 -1.4
Arm fat-free mass (left) 0.1 0.5 0.9 -0.4 -0.9
Number of operations (self-reported) 1.7 2.5 3.4 -1.8 1.3
Average weekly beer plus cider intake 0.9 1.3 2.4 -1.5 -0.4
Irritability 0.1 0.1 0.2 -0.2 -0.5
Risk taking 0.6 0.9 1.7 -1.3 -0.1
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.4 0.6 0.1
Fractured/broken bones in last 5 years 0.4 0.5 0.7 0.6 -0.8
Age started oral contraceptive pill 0.3 0.4 0.6 -0.8 0.4
Diastolic blood pressure, automated reading 1.3 4.1 5.6 2.4 -1.6
Ever depressed for a whole week 1.2 1.5 2.7 -0.6 1.6
Unable to work because of sickness or disability 0.6 0.7 1.5 -0.1 -1.2
Commuting to job workplace: Cycle 0.0 0.1 0.1 0.2 0.2
Myopia 2.1 3.0 4.3 -1.3 2.1
Vascular/heart problems diagnosed by doctor 0.2 0.5 1.0 -0.2 1.0
Cholesterol lowering medication 0.2 0.3 0.5 -0.2 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 0.8 -0.9 -0.1
Pain experienced in last month 0.1 0.2 0.3 0.4 0.5
Supplements: Calcium 0.3 0.3 0.5 0.7 0.1
Basal cell carcinoma (self-reported) 0.4 0.5 0.8 0.9 0.4
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.1 -0.0 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.3 -1.1 -0.1
Heart disease (siblings) 0.4 0.5 0.6 -0.6 0.8
Alcohol drinker status: Previous 0.8 0.9 1.2 -0.8 -1.1
Pack years of smoking 0.2 0.2 0.4 -0.6 -0.3
Impedance of whole body 1.4 7.2 8.1 2.5 -2.8
Leg fat mass (left) 0.6 2.4 4.6 0.5 -2.1
Arm predicted mass (left) 0.1 0.6 1.0 -0.4 -1.0