TWAS hub - C10orf95

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Skin Sun Exposed Lower leg	0.1640	0.0570	2.6e-07	0.129	NA	0.161	NA	0.116	7.5e-11	NA	2.9e-13	NA	7.6e-10
2	GTEx	Thyroid	0.1020	0.0500	1.1e-03	0.016	NA	0.023	NA	0.007	2.0e-02	NA	6.6e-03	NA	8.4e-02
3	TCGA	Prostate Adenocarcinoma	0.0183	0.0107	6.7e-03	0.027	0.005	0.011	NA	0.018	7.6e-04	0.094	2.5e-02	NA	4.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Allergy or Eczema	16.2	42.6	59.0	4.7	6.9	7.7
Hayfever, allergic rhinitis or eczema	13.6	29.6	42.0	4.0	5.6	6.5
Allergy	12.1	27.8	41.0	-3.7	-5.4	-6.4
Standing height	8.6	85.4	151.3	-6.7	-7.7	-12.3
Height	8.5	164.6	302.8	-9.1	-10.4	-17.4
Hearing difficulty/problems with background noise	8.3	13.2	23.0	-2.5	-3.2	-4.8
Forced expiratory volume in 1-second (FEV1), predicted	8.0	16.6	31.0	-2.1	-3.8	-5.6
Ulcerative Colitis	7.9	11.5	20.5	-2.4	-2.9	-4.5
Sitting height	7.8	55.5	102.0	-4.6	-6.5	-10.1
Prostate Cancer	7.4	10.3	17.4	2.9	2.3	4.2
Past tobacco smoking	7.2	13.3	20.2	4.3	1.0	4.5
Medication: Atenolol	6.4	8.0	11.3	-1.4	-3.4	-3.3
Pain type(s) experienced in last month: Hip pain	6.3	8.0	10.2	2.6	3.2	2.7
Comparative height size at age 10	6.1	33.8	65.1	-4.2	-4.3	-8.1
Qualifications: A levels/AS levels or equivalent	5.1	11.2	16.9	-2.0	-4.1	-3.6
Basal cell carcinoma (self-reported)	5.1	6.1	7.6	-2.8	-2.1	-2.5
Hearing difficulty/problems: Yes	4.8	7.3	12.8	-2.0	-2.2	-3.6
Pulse wave peak to peak time	4.7	5.5	6.5	-2.2	-2.3	-2.5
Ever smoked	4.6	8.1	13.4	-3.2	-0.7	-3.7
Smoking status: Previous	4.4	6.6	10.2	-3.2	-0.6	-3.0
Waist Hip Ratio (WHR)	4.3	19.3	25.3	-3.6	-5.0	-4.4
Hayfever/allergic rhinitis (self-reported)	4.3	5.7	11.0	0.6	2.4	3.3
Length of working week for main job	4.3	4.7	7.3	-1.7	-2.0	-2.7
Reaction Time	4.2	8.0	12.0	3.0	1.6	3.5
Ulcerative Colitis (UC)	4.0	7.5	11.7	-2.3	-2.3	-3.4
Worrier / anxious feelings	4.0	7.5	13.8	3.7	-0.8	2.8
BMI	3.7	21.4	46.6	2.0	6.8	3.7
Hand grip strength (left)	3.7	9.6	15.3	-3.9	-1.0	-3.6
Blood White Count	3.6	26.4	44.8	-3.3	-4.8	-6.7
Body mass index (BMI)	3.6	15.5	36.2	1.5	6.0	2.8
Forced vital capacity (FVC)	3.5	13.3	24.0	-2.8	-2.9	-4.9
Mean Putamen Volume	3.4	3.9	6.9	-2.0	-1.0	-2.6
Irritable Bowel Disease (IBD)	3.3	7.9	11.7	-2.5	-2.4	-3.4
Medication: Ibuprofen (e.g. Nurofen)	3.3	4.2	5.1	2.0	2.3	1.9
Bipolar Disorder (2011)	3.2	3.1	5.7	-0.4	-2.4	-1.9
Schizophrenia (2018)	3.1	6.4	17.1	4.1	-1.5	-0.1
Impedance of leg (right)	3.1	15.0	33.1	-0.5	-5.8	-3.4
Impedance of leg (left)	3.1	15.3	33.6	-0.7	-5.8	-3.4
Smoking Status	3.0	7.2	12.2	-3.0	0.6	-3.5
Body Mass Index (BMI) (2010)	2.9	4.0	9.8	1.0	3.1	1.1
Crohns Disease (2012)	2.9	4.6	8.2	-1.7	-1.6	-2.9
Schizophrenia (2014)	2.9	6.4	17.7	4.2	-1.2	-0.1
Diabetes (mother)	2.8	3.6	4.3	-1.6	-2.1	-2.0
Asthma	2.8	5.5	9.2	0.4	2.6	3.0
Leg pain on walking	2.8	3.5	4.7	1.9	2.2	1.5
Cardiovascular Disease	2.7	8.9	16.4	-0.5	-4.0	-3.2
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.2	4.5	-1.5	-2.1	-1.7
Fractured/broken bones in last 5 years	2.7	3.5	6.6	2.6	0.9	1.8
Diastolic blood pressure, automated reading	2.7	8.4	17.2	0.6	-4.1	-2.8
Systolic Blood Pressure	2.6	13.1	24.8	3.8	-5.0	0.2
Headache pain in last month	2.6	4.4	9.8	1.0	3.1	1.6
Arm fat percentage (left)	2.6	10.2	25.1	1.5	5.0	1.8
Type 2 Diabetes (T2D) (2012)	2.5	2.9	4.3	1.4	-2.1	-1.5
Blood Platelet Count	2.5	29.1	51.0	-3.4	-5.0	-7.1
Trunk fat-free mass	2.5	14.2	29.6	-3.5	-0.7	-5.4
Forced vital capacity (FVC), Best measure	2.5	9.0	15.8	-2.3	-2.4	-4.0
Medication: Lisinopril	2.5	3.3	7.0	-0.5	-2.6	-1.6
Systolic blood pressure, automated reading	2.4	7.1	16.6	4.1	-2.0	0.9
Eye problems/disorders: Diabetes related eye disease	2.4	2.7	7.4	-2.7	0.0	-0.8
Hand grip strength (right)	2.4	6.5	9.6	-3.1	-0.7	-3.1
Arm fat percentage (right)	2.4	9.3	23.8	1.2	4.9	1.6
Trunk predicted mass	2.4	13.5	28.5	-3.4	-0.6	-5.3
Asthma (self-reported)	2.4	4.8	8.1	0.4	2.5	2.9
Bipolar Disorder or Schizophrenia	2.3	5.5	13.0	3.6	-1.8	-0.7
Pulse wave Arterial Stiffness index	2.3	2.6	3.1	1.5	1.8	1.6
Medication: Aspirin	2.3	3.0	6.8	-0.0	-1.5	-2.6
Relative age of first facial hair	2.2	4.5	6.5	-2.6	-1.8	-2.0
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	4.7	1.1	1.3	2.2
High blood pressure	2.2	6.0	10.0	-0.2	-3.2	-2.9
Medication for pain relief, constipation, heartburn	2.2	3.8	10.4	-3.2	-0.8	-0.4
Medication: Aspirin	2.2	3.0	6.2	0.2	-1.6	-2.5
Mother’s age at death	2.2	2.8	5.9	-0.7	-2.4	-1.4
Medication: Bendroflumethiazide	2.2	3.4	4.9	-0.8	-2.2	-2.1
Vascular/heart problems diagnosed by doctor	2.2	5.9	10.4	0.1	3.2	2.7
Major Depression (MDD)	2.1	2.5	4.1	0.8	-2.0	-1.7
Exposure to tobacco smoke at home	2.1	2.4	7.0	2.6	0.3	-0.1
Osteoarthritis (self-reported)	2.0	2.6	5.9	1.2	2.4	0.8
Impedance of whole body	2.0	10.3	24.7	-0.0	-5.0	-2.5
Pulse rate	1.9	3.3	3.7	1.9	1.8	1.7
Eye problems/disorders: None of the above	1.9	2.2	3.0	1.7	1.2	1.5
Migraine (self-reported)	1.9	2.3	4.7	-2.2	1.4	-0.5
Hypertension (Self-reported)	1.9	5.3	9.5	0.3	-3.1	-2.5
Ever had bowel cancer screening	1.9	2.2	2.6	-1.3	-1.5	-1.6
Friendships satisfaction	1.9	2.3	5.1	2.3	-0.4	1.3
Forced expiratory volume in 1-second (FEV1)	1.8	5.9	11.3	-2.0	-1.5	-3.4
Lung cancer (father)	1.8	2.1	4.6	-0.3	-1.3	-2.1
Peak expiratory flow (PEF)	1.8	4.1	7.4	-1.8	-1.3	-2.7
Medication: Paracetamol	1.8	3.0	7.4	2.7	0.9	0.9
Birth weight	1.8	3.8	8.6	-2.9	0.0	-1.7
Medication: Ibuprofen	1.8	2.1	2.9	1.7	1.6	0.9
Financial situation satisfaction	1.8	2.3	3.0	-1.0	-1.7	-1.7
Worry (Nagel 2018)	1.7	3.5	5.1	1.1	-2.0	2.3
Had menopause	1.7	2.1	2.6	1.6	1.5	1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.9	6.2	-0.6	-2.3	-2.5
Medication: Lansoprazole	1.7	2.0	3.6	1.9	0.7	1.3
Pain experienced in last month	1.7	2.9	7.5	-1.0	-2.7	-0.5
Respiratory disease	1.6	3.5	8.6	0.6	1.3	2.9
Father’s age at death	1.6	2.1	2.9	-0.8	-1.7	-1.7
Blood clot in the leg (DVT)	1.6	2.1	3.3	1.8	0.7	1.6
Chronic bronchitis/emphysema (mother)	1.6	1.9	2.2	-1.3	-1.4	-1.5
Qualifications: College or University degree	1.6	5.1	9.7	1.3	-3.1	-2.0
Qualifications: nursing, teaching	1.6	2.5	5.0	0.3	-1.5	-2.2
Arm fat mass (left)	1.6	6.4	19.0	0.5	4.4	0.1
Leg fat percentage (left)	1.6	5.8	15.3	1.1	3.9	0.9
Ever depressed for a whole week	1.6	1.9	3.6	-0.4	-1.4	-1.9
Arm fat mass (right)	1.5	6.0	17.6	0.6	4.2	0.2
Body fat percentage	1.5	5.8	15.4	1.2	3.9	0.7
Leg fat percentage (right)	1.5	5.5	14.2	1.2	3.8	0.9
Shortness of breath walking on level ground	1.5	1.8	2.7	0.9	1.6	1.3
Neck or shoulder pain in last month	1.5	2.1	4.5	2.1	1.3	0.5
Arm predicted mass (right)	1.5	7.7	18.3	-2.1	0.5	-4.3
Whole body fat-free mass	1.5	8.4	18.1	-2.6	0.6	-4.2
Whole body water mass	1.5	8.3	17.6	-2.6	0.7	-4.2
Average weekly champagne plus white wine intake	1.5	2.1	4.4	1.0	0.9	2.1
Ever had prostate specific antigen (PSA) test	1.5	1.7	2.1	-1.2	1.3	1.4
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	3.5	1.9	0.5	1.4
Blood Eosinophil Count	1.4	10.5	15.8	-1.1	-4.0	-3.8
Age when periods started (menarche)	1.4	3.3	6.5	-2.6	-0.9	-1.6
Serious illness, injury or assault to yourself	1.4	1.7	2.0	1.4	1.1	1.4
Nervous feelings	1.4	2.6	5.1	1.1	-2.3	1.3
Arm fat-free mass (right)	1.4	7.3	17.4	-2.1	0.5	-4.2
Mean time to correctly identify matches	1.4	2.7	5.4	2.3	0.5	1.6
Knee pain experienced in last month	1.4	2.2	5.2	-0.6	2.3	-1.0
Ever taken oral contraceptive pill	1.4	1.5	2.3	-1.4	1.5	-0.4
Commuting to job workplace: Public transport	1.4	1.7	4.1	-0.0	-2.0	-0.9
Fed-up feelings	1.3	2.4	4.4	-0.5	2.1	1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	5.4	0.1	-2.3	-1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	7.7	-1.7	-1.4	-2.8
Birth weight of first child	1.3	2.4	4.7	-2.2	-0.3	-1.6
Angina (self-reported)	1.3	1.7	3.2	0.1	-1.4	-1.8
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.0	-0.9	1.7	0.9
Tinnitus: Yes, now most or all of the time	1.3	1.5	1.8	-1.1	-1.2	-1.3
Basal metabolic rate	1.3	7.3	15.4	-2.3	1.1	-3.9
Arm fat-free mass (left)	1.3	6.8	15.5	-2.0	0.9	-3.9
Arm predicted mass (left)	1.3	6.8	15.9	-2.0	0.8	-4.0
Schizophrenia vs Biploar Disorder	1.2	1.6	3.8	1.9	0.3	1.0
Crohns Disease (2017)	1.2	2.7	3.4	-1.8	-1.2	-1.8
Trunk fat percentage	1.2	4.8	13.2	1.1	3.6	0.4
Stomach or abdominal pain in last month	1.2	1.5	3.2	0.6	1.8	1.0
Medication: Simvastatin	1.2	1.8	3.9	1.2	2.0	-0.4
Hip circumference	1.2	5.2	14.4	-0.6	3.8	-0.8
Age at last live birth	1.2	1.8	2.5	-1.6	-1.3	-1.1
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.2	0.5	1.8	1.0
Fasting Glucose	1.1	1.3	2.3	-1.1	-0.6	-1.5
Heel T-Score	1.1	8.8	15.4	-0.9	-3.9	-3.2
Angina	1.1	1.5	2.6	0.0	-1.3	-1.6
Maternal smoking around birth	1.1	1.6	3.4	-0.6	1.0	-1.8
Qualifications: CSEs or equivalent	1.1	1.4	3.7	0.0	1.9	0.7
Impedance of arm (right)	1.1	5.2	12.2	-0.4	-3.5	-1.8
Breastfed as a baby	1.1	1.4	2.0	-1.4	-1.4	-0.4
Pulse wave reflection index	1.1	1.3	3.2	-1.8	0.0	-0.9
Medication: Ventolin 100micrograms inhaler	1.1	1.4	2.6	0.5	1.2	1.6
Medication: Blood pressure	1.1	2.0	3.3	0.1	-1.8	-1.6
Leg fat mass (right)	1.1	4.3	12.3	0.3	3.5	-0.8
Supplements: Vitamin C	1.1	1.2	3.2	-0.5	1.8	-0.6
Illnesses of father: Heart disease	1.1	1.5	4.1	0.1	-0.8	-2.0
Leg fat mass (left)	1.1	4.3	12.5	0.3	3.5	-0.6
Breast Cancer	1.0	2.5	5.5	2.4	0.5	1.3
Coronary Artery Disease (CAD)	1.0	1.2	2.9	0.5	-1.7	-0.6
LDL Cholesterol	1.0	1.5	2.9	1.0	1.7	0.8
Ever had hysterectomy (womb removed)	1.0	1.2	2.7	-0.0	0.9	1.6
Supplements: Zinc	1.0	1.1	2.8	-0.5	0.3	-1.7
Fluid intelligence score	1.0	2.1	4.1	-0.3	-2.0	-1.4
Weight	1.0	4.9	7.7	-1.4	2.2	-2.8
Hair/balding pattern: Pattern 3	1.0	1.4	3.3	0.3	-0.9	-1.8
Illnesses of mother	1.0	1.2	2.2	1.0	1.5	0.8
Impedance of arm (left)	1.0	4.8	12.1	-0.1	-3.5	-1.5
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.0	-1.0	-1.4	-1.4
Worry too long after embarrassment	1.0	1.7	3.5	1.1	0.5	1.9
Whole body fat mass	1.0	4.2	12.2	0.1	3.5	-0.7
Suffer from ‘nerves’	1.0	1.6	3.4	1.1	-1.9	0.2
Family relationship satisfaction	1.0	1.3	3.0	0.8	-1.7	-0.4
Commuting to job workplace: Walk	1.0	1.1	2.0	1.4	-1.1	0.2
Mineral and other dietary supplements	1.0	1.3	1.9	0.3	-1.4	1.4
Medication: Blood pressure	1.0	1.8	3.0	-0.4	-1.5	-1.7
Intelligence (Savage-Jansen 2018)	0.9	2.8	4.5	0.2	-1.9	-2.1
Alzheimer’s Disease (in father)	0.9	1.0	1.5	1.2	0.2	1.2
Lung FVC	0.9	4.4	7.1	1.0	2.3	2.7
Neuroticism	0.9	2.1	5.2	1.0	-0.3	2.3
Severe depression (siblings)	0.9	1.0	1.5	1.1	0.4	1.2
Leg fat-free mass (left)	0.9	4.8	7.6	-1.5	2.2	-2.7
Current tobacco smoking	0.9	1.4	3.5	-0.7	0.5	-1.9
Chronic bronchitis/emphysema (father)	0.9	1.1	2.8	0.1	0.7	1.7
Leg predicted mass (left)	0.9	4.8	7.7	-1.6	2.0	-2.8
Trunk fat mass	0.9	3.7	9.5	-0.1	3.1	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.0	1.4	0.6	1.3
Medication: Ramipril	0.9	1.1	2.1	1.1	-1.5	-0.2
High blood pressure (siblings)	0.9	1.3	2.2	0.6	-1.5	-1.2
Leg fat-free mass (right)	0.9	4.8	7.7	-1.7	1.9	-2.8
Average weekly red wine intake	0.9	1.3	3.2	-0.2	-1.8	-0.8
Long-standing illness, disability or infirmity	0.9	1.4	3.4	-0.7	-0.7	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.7	-1.3	-0.4	-1.0
Leg predicted mass (right)	0.9	4.9	7.9	-1.7	1.9	-2.8
Medication: Atorvastatin	0.9	1.1	3.1	-0.3	-1.8	-0.2
Neuroticism (2016)	0.8	1.2	2.0	0.9	0.9	1.4
Lung FEV1/FVC ratio	0.8	3.9	8.8	0.2	3.0	1.7
Number of incorrect matches in round	0.8	1.4	2.0	1.4	0.2	1.4
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.2	-0.9	-1.0	-1.1
Mood swings	0.8	1.4	2.1	0.2	1.4	1.5
Smoking status: Current	0.8	1.3	3.4	-0.7	0.4	-1.8
Verbal and Numeric Reasoning (VNR)	0.7	1.6	2.5	0.4	-1.5	-1.6
Rheumatoid Arthritis	0.7	1.0	1.1	-0.8	-1.1	-1.1
High blood pressure (mother)	0.7	0.9	1.4	1.2	-1.0	0.5
Waist circumference	0.7	2.4	4.3	-1.0	2.1	-1.4
Mouth/teeth dental problems	0.7	1.0	2.4	0.5	-1.6	-0.6
Exposure to tobacco smoke outside home	0.7	0.9	2.6	-0.2	-0.4	-1.6
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.9	-0.8	1.4	0.3
Overall health rating	0.7	1.4	2.5	0.4	1.6	1.3
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.1	-0.1	-1.4	-0.6
Supplements: Calcium	0.7	0.8	1.4	0.8	1.2	0.4
Heart disease (siblings)	0.7	0.9	1.7	0.0	-0.9	-1.3
Depressed Affect (Nagel 2018)	0.6	1.3	2.2	-0.3	1.5	1.3
Neuroticism (Nagel 2018)	0.6	1.4	3.7	0.3	-0.7	1.9
Lupus	0.6	0.8	2.0	-1.4	0.4	-0.6
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.1	-1.1	-0.7	-0.8
Vitamin and mineral supplements	0.6	0.8	0.8	0.9	-0.8	0.9
Medication: Co-codamol	0.6	0.7	1.5	1.2	0.5	0.5
Relative age voice broke	0.6	0.9	1.7	-0.4	-0.9	-1.3
Supplements: Glucosamine	0.6	0.8	1.1	-0.8	0.8	-1.0
Medication: Levothyroxine sodium	0.6	1.0	1.6	1.2	0.3	1.2
Qualifications: None of the above	0.6	1.3	2.0	-1.2	1.4	0.8
Neuroticism score	0.6	1.3	3.5	0.7	0.3	1.9
Happiness	0.6	0.7	1.0	1.0	0.8	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.1	0.0	0.1	1.5
Age at first live birth	0.6	1.0	1.4	-1.2	-1.2	-0.4
Medication: Allopurinol	0.6	0.8	1.4	0.2	-1.2	-1.0
Loneliness, isolation	0.6	0.8	1.3	1.1	0.1	1.1
Eye problems/disorders: Cataract	0.6	0.6	1.5	-1.2	-0.7	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.6	-1.3	0.7	0.8
Medication: Paracetamol	0.6	1.0	2.8	1.7	0.4	0.2
Irritability	0.6	1.0	2.8	-1.7	0.0	-0.5
Commuting to job workplace: Cycle	0.6	0.8	1.6	0.1	-1.3	-0.8
Cholesterol lowering medication	0.6	0.9	2.1	1.4	0.6	-0.4
Bipolar Disorder (2018)	0.5	0.8	1.0	0.6	-1.0	-1.0
Hypothyroidism (self reported)	0.5	1.2	2.9	-0.6	-1.7	-0.7
Alcohol usually taken with meals	0.5	0.8	2.0	1.4	-0.6	-0.0
Hair/balding pattern: Pattern 2	0.5	0.6	0.9	-1.0	0.5	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.3	-0.7	-1.2	-0.1
Medication: Amlodipine	0.5	0.7	1.6	1.3	0.1	0.8
Heart disease (mother)	0.5	0.6	1.6	1.3	-0.1	0.2
Chest pain or discomfort	0.5	0.7	1.7	0.4	1.3	0.3
Had major operations	0.5	0.6	1.3	-1.1	0.4	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.6	0.2	0.0	-1.3
Guilty feelings	0.5	0.7	1.3	0.8	0.3	1.2
Supplements: Fish oil (including cod liver oil)	0.5	0.6	0.8	0.6	0.8	-0.9
Unable to work because of sickness or disability	0.5	0.7	1.0	-0.6	-1.0	-0.9
Average weekly spirits intake	0.4	0.5	0.9	-0.7	1.0	0.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.1	-0.4	0.2	1.1
Pack years adult smoking proportion	0.4	0.7	1.8	1.3	0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.1	0.3	1.1	0.6
Heart attack	0.4	0.6	1.3	0.5	-0.4	-1.1
Time employed in main current job	0.4	0.5	1.4	-0.3	-1.2	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.5	0.0	0.5	-1.2
Mouth/teeth dental problems: Dentures	0.4	0.7	1.7	-0.5	1.3	-0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	1.2	-1.1	0.7	0.2
Gout (self-reported)	0.4	0.5	0.8	0.7	-0.9	-0.4
Comparative body size at age 10	0.4	1.2	3.6	0.2	1.9	0.2
Alcohol intake frequency.	0.4	0.8	1.8	-0.6	0.5	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.1	0.3	0.3	-1.1
Illnesses of siblings: Diabetes	0.4	0.5	1.2	-0.5	-0.3	-1.1
Number of self-reported non-cancer illnesses	0.4	0.6	0.7	0.8	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.2	0.4	-0.4	-1.1
Triglycerides	0.3	0.6	1.0	-0.6	-1.0	-0.6
Blood Red Count	0.3	3.2	5.6	-0.9	-2.4	-1.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.8	0.6	0.7	-0.9
Chronotype (morning person)	0.3	0.7	1.1	-0.9	0.3	1.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.9	-0.4	-0.9	-0.3
Diabetes (father)	0.3	0.4	1.0	-1.0	0.4	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	0.6	0.5	0.5
Pain all over the body in last month	0.3	0.3	0.4	-0.6	0.3	0.7
Medication: Cholesterol lowering	0.3	0.5	1.3	0.2	1.2	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.1	0.7	-1.0	-0.0
Emphysema/chronic bronchitis	0.3	0.4	0.9	0.2	1.0	0.4
Medication: Seretide 50 evohaler	0.3	0.3	0.8	-0.9	0.1	-0.4
Number of full sisters	0.3	0.3	0.6	-0.5	0.8	0.4
Medication for cholesterol	0.3	0.5	1.1	0.3	0.4	1.1
Breast cancer (self-reported)	0.3	0.4	1.0	1.0	-0.4	-0.2
Wears glasses or contact lenses	0.3	0.3	0.7	-0.1	0.5	-0.8
Eye problems/disorders: Glaucoma	0.3	0.3	0.8	-0.4	-0.3	-0.9
High cholesterol (Self-reported)	0.3	0.5	0.7	0.7	0.8	-0.6
Alcohol drinker status: Never	0.3	0.3	1.0	1.0	0.0	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.8	0.2	0.9	-0.3
Pack years of smoking	0.3	0.5	1.0	1.0	0.2	-0.6
Depression (Nagel 2018)	0.2	0.3	0.8	0.2	0.1	0.9
Age at First Birth	0.2	0.2	0.4	-0.3	-0.6	-0.5
Primary Biliary Cirrhosis	0.2	0.4	0.4	-0.6	-0.6	-0.6
Number of treatments/medications taken	0.2	0.4	0.7	0.7	-0.4	-0.8
Sensitivity / hurt feelings	0.2	0.3	0.8	-0.1	-0.9	0.3
Medication for hormone replacement therapy	0.2	0.2	0.2	-0.5	-0.4	-0.4
Multivitamins +/- minerals	0.2	0.2	0.4	-0.6	0.2	-0.5
Had other major operations	0.2	0.2	0.4	0.6	0.4	0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.5	0.2	-0.7	-0.3
Financial difficulties in last 2 years	0.2	0.3	0.5	0.6	0.1	-0.7
Diabetes (self-reported)	0.2	0.4	1.0	0.1	0.2	-1.0
Illnesses of siblings	0.2	0.2	0.5	-0.4	0.0	0.7
Falls in the last year	0.2	0.3	0.7	0.3	0.4	-0.8
Noisy workplace	0.2	0.3	0.6	0.3	0.8	0.3
Depression (self-reported)	0.2	0.3	0.7	0.0	0.8	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.8	0.2	-0.5	-0.9
Hair/balding pattern: Pattern 4	0.2	0.5	0.7	-0.8	-0.2	-0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.0	0.4	0.1	1.0
Number of full brothers	0.2	0.2	0.5	0.2	-0.2	0.7
Wheeze or whistling in the chest in last year	0.2	0.4	0.7	-0.6	0.8	0.5
Number of children fathered	0.2	0.2	0.6	-0.2	0.0	-0.8
Medication: Omeprazole	0.2	0.3	0.8	-0.1	0.0	-0.9
Diabetes diagnosed by doctor	0.2	0.4	0.6	-0.0	0.7	-0.8
Back pain experienced in last month	0.2	0.4	0.8	0.0	0.5	-0.9
Osteoporosis (self-reported)	0.2	0.3	0.6	0.5	0.1	0.8
Medication: Gliclazide	0.2	0.2	0.5	0.7	-0.0	0.2
Miserableness	0.2	0.4	0.6	-0.4	0.8	-0.6
Number of operations (self-reported)	0.2	0.3	0.8	0.0	0.9	0.1
Average weekly beer plus cider intake	0.2	0.3	0.5	-0.6	-0.7	-0.2
Risk taking	0.2	0.4	1.0	0.1	0.3	-1.0
Myopia	0.2	0.3	0.5	0.5	0.5	0.7
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.4	-0.6	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.2	0.4	-0.0
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	0.6	0.0	0.1
Ovarian Cancer	0.1	0.1	0.3	0.6	0.1	0.3
HbA1C	0.1	0.1	0.1	0.3	0.3	0.2
Medication: Metformin	0.1	0.2	0.4	-0.3	0.3	-0.6
Townsend deprivation index at recruitment	0.1	0.2	0.4	-0.3	0.6	-0.3
Average weekly fortified wine intake	0.1	0.2	0.3	0.3	0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.3	0.6	-0.2	0.5
Taking other prescription medications	0.1	0.1	0.2	0.4	0.1	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.1	0.2	-0.4	-0.3
Prospective memory result	0.1	0.1	0.4	-0.1	0.2	0.6
Tense / ‘highly strung’	0.1	0.2	0.6	-0.1	-0.2	0.8
Loud music exposure frequency	0.1	0.1	0.2	-0.3	-0.1	-0.5
Glaucoma (self-reported)	0.1	0.1	0.3	0.5	0.2	0.1
Health satisfaction	0.1	0.1	0.2	0.5	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.3	-0.0	0.6
Pulse rate, automated reading	0.1	0.4	1.0	1.0	0.4	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	-0.2	0.5	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.0	-0.1	0.8
Hearing aid user	0.1	0.1	0.4	-0.6	-0.2	-0.1
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.4	-0.5	-0.0
Age started oral contraceptive pill	0.1	0.1	0.2	-0.4	0.2	-0.5
HDL Cholesterol	0.0	0.0	0.1	-0.2	0.3	-0.0
Hair Pigment	0.0	0.2	0.2	0.5	-0.4	-0.2
Tanning	0.0	0.5	1.3	-0.1	0.3	-1.2
Number of live births	0.0	0.0	0.0	0.1	0.1	0.0
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	0.1	-0.2	-0.2

Hub : Genes

C10orf95

Models

Trait associations