Hub : Genes

C11orf35

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Esophagus Mucosa 0.3510 0.0690 1.5e-07 0.024 NA 0.151 NA 0.143 9.9e-03 NA 2.6e-10 NA 8.6e-10
2 GTEx Pancreas 0.3410 0.0940 2.1e-04 0.025 NA 0.048 NA 0.044 3.1e-02 NA 4.2e-03 NA 6.1e-03
3 GTEx Thyroid 0.1570 0.0510 8.2e-04 -0.003 NA 0.065 NA -0.004 8.0e-01 NA 9.8e-06 NA 9.2e-01
4 GTEx Whole Blood 0.1340 0.0500 3.2e-03 0.054 NA 0.017 NA 0.047 9.2e-06 NA 8.6e-03 NA 3.5e-05
5 METSIM Adipose 0.0843 0.0335 5.3e-03 0.026 0.013 0.038 0.033 0.041 7.8e-05 0.0035 2.2e-06 7.6e-06 8.0e-07
6 TCGA Prostate Adenocarcinoma 0.0569 0.0297 1.1e-03 0.027 0.025 0.028 NA 0.025 6.8e-04 0.0010 6.1e-04 NA 1.0e-03
7 TCGA Soft Tissue Sarcoma 0.0430 0.0250 7.5e-03 0.020 0.029 0.010 NA 0.019 2.1e-02 0.0076 7.5e-02 NA 2.6e-02
8 TCGA Thyroid Carcinoma 0.0820 0.0470 3.5e-03 0.000 0.015 0.026 NA 0.002 3.3e-01 0.0120 1.3e-03 NA 1.9e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 5.4 0.8 -2.3 0.3 0.7 0.0 0.0 1.3 -0.3
Bipolar Disorder or Schizophrenia 0.3 0.8 2.0 -1.4 -0.5 0.9 -1.0 0.0 -0.5 -0.6 -1.2
Depressed Affect (Nagel 2018) 0.8 1.7 4.0 -2.0 -1.0 -0.9 -1.6 -1.0 -0.6 -1.8 0.2
Depression (Nagel 2018) 1.3 2.0 3.8 -2.0 -1.1 -1.9 -1.3 -0.5 -0.2 -1.8 1.4
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.1 -1.1 -0.3 1.0 -0.0 0.9 -0.7 -1.8 0.0
Neuroticism (Nagel 2018) 0.4 0.8 2.7 -1.6 -1.1 -0.2 -1.1 -1.1 -0.3 -0.5 -0.0
Schizophrenia (2018) 0.9 2.0 5.8 -2.4 1.0 0.6 -2.1 0.0 -0.9 -1.6 -0.8
Schizophrenia vs Biploar Disorder 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 0.1 0.1 0.4 -0.4 -0.1 0.1 -0.6 -0.1 -0.5 0.4 0.0
Alzheimer’s Disease (in mother) 1.1 1.3 5.0 -0.1 1.6 0.6 0.6 1.3 -0.3 -2.2 -0.4
Alzheimer’s Disease (in father) 1.4 1.5 5.3 -1.4 -0.9 -0.6 -1.8 0.2 -0.5 -0.3 -2.3
Alzheimer’s Disease (including proxy) 0.8 1.2 4.0 -0.6 1.5 0.2 -0.5 1.1 -0.1 -2.0 -1.1
Crohns Disease (2017) 0.6 1.2 5.2 0.4 2.3 0.5 -0.1 0.8 -0.2 -1.7 0.9
Irritable Bowel Disease (IBD) 0.3 0.8 4.1 0.9 2.0 0.1 -0.2 -0.2 0.4 -0.8 0.5
Ulcerative Colitis (UC) 0.3 0.6 1.9 0.4 1.2 -1.0 -0.5 -1.4 0.4 0.3 -0.1
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.7 1.3 5.0 1.5 0.4 0.7 0.1 -0.5 0.7 2.2 -1.1
Verbal and Numeric Reasoning (VNR) 0.4 1.0 4.3 -2.1 -0.8 0.6 0.2 0.3 -0.6 -1.4 0.3
Breast Cancer 1.2 2.9 12.1 -3.5 -0.4 0.6 -1.6 -0.4 1.3 -2.2 0.9
Ovarian Cancer 0.6 0.7 2.0 -0.6 -0.1 -1.4 -0.7 1.0 -1.2 -0.7 -0.0
Prostate Cancer 0.7 1.0 3.3 1.0 0.8 0.6 0.7 -1.1 0.8 1.8 -0.9
Age at First Birth 0.1 0.1 0.6 -0.1 -0.8 0.0 -0.0 -0.2 0.0 0.0 0.0
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.0 0.1 0.5 0.0 0.0 0.0 0.0 -0.7 0.0 0.0 0.0
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.1 0.2 1.3 -0.2 0.0 -1.2 -0.1 0.0 0.0 0.0 0.0
Mean Putamen Volume 1.5 1.7 8.0 0.9 2.8 1.0 -0.1 0.4 -1.8 0.3 -0.6
Fasting Glucose 0.6 0.7 2.9 -1.0 0.5 0.4 1.7 -0.6 -0.1 -1.0 0.3
HbA1C 2.9 3.3 13.1 0.5 -3.6 -0.9 1.0 -1.0 2.5 -1.0 1.6
HDL Cholesterol 0.7 1.2 6.7 2.6 -0.8 1.0 0.3 1.0 0.0 0.0 0.0
LDL Cholesterol 0.1 0.1 0.6 -0.8 0.4 0.4 0.0 0.4 0.0 0.0 0.0
Lupus 6.3 9.5 40.2 -3.2 2.8 -0.9 -2.7 2.6 -1.2 -6.3 1.5
Neuroticism (2016) 1.6 2.3 8.7 -1.1 0.1 -1.2 -2.9 -0.1 -2.1 1.5 -0.2
Primary Biliary Cirrhosis 1.8 2.6 7.5 -1.2 0.7 -2.7 0.0 1.8 -0.5 -2.6 1.1
Rheumatoid Arthritis 0.3 0.4 1.1 -0.3 0.2 -0.7 -0.1 0.0 0.8 -0.7 1.0
Schizophrenia (2014) 0.5 1.1 4.0 -2.0 -0.3 1.2 -0.7 0.0 -0.9 -0.7 -1.2
Triglycerides 0.2 0.3 0.7 -0.7 -0.6 -0.8 0.7 0.8 0.0 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.2 0.2 1.8 0.0 0.2 0.0 0.0 0.0 0.0 1.3 -0.2
Blood Eosinophil Count 0.3 2.6 10.5 -1.4 1.1 2.0 -1.1 -0.3 -1.4 -3.2 0.1
Blood Platelet Count 1.4 15.8 56.0 2.8 5.3 7.5 4.2 -0.1 3.1 2.1 1.4
Blood Red Count 0.3 2.5 11.4 -1.6 0.2 0.3 1.0 -3.4 1.7 1.2 0.8
Blood White Count 0.4 2.9 15.8 1.0 4.0 1.7 0.4 0.4 0.6 0.3 -1.7
Heel T-Score 0.1 0.8 2.7 -1.0 -0.7 -1.6 -0.5 -0.3 0.9 -0.7 0.7
BMI 0.6 3.5 7.2 1.1 2.7 1.5 1.8 1.3 0.4 -2.4 2.6
Height 0.2 4.1 14.0 -2.2 2.4 0.7 -0.6 2.4 -1.3 -3.7 0.5
Waist Hip Ratio (WHR) 0.5 2.3 10.2 -2.0 0.5 0.9 0.2 1.8 0.3 -3.2 0.6
Systolic Blood Pressure 0.3 1.3 4.3 0.8 2.1 0.3 -1.0 0.1 0.4 2.0 -0.1
Smoking Status 1.1 2.6 5.5 1.9 0.7 2.4 1.6 2.2 1.2 1.5 0.1
Allergy or Eczema 1.5 3.8 11.0 -1.4 1.9 1.4 -3.3 1.1 -2.4 -0.4 -2.3
Cardiovascular Disease 0.7 2.2 6.0 -2.4 1.3 1.1 -2.5 0.1 -0.7 -1.1 0.8
Hypothyroidism (self reported) 2.5 5.8 29.1 -2.3 -0.1 0.1 1.1 -1.2 0.8 -5.4 2.9
Respiratory disease 0.6 1.3 4.3 -0.1 -0.6 0.4 -1.4 0.7 -2.1 0.9 -1.6
Type 2 Diabetes (T2D) (2018) 1.1 2.1 4.1 2.0 1.2 2.0 0.5 1.8 1.1 1.1 -1.3
Lung FEV1/FVC ratio 0.2 1.1 3.8 -0.0 -0.7 -0.9 0.2 -1.5 1.9 0.6 0.7
Lung FVC 0.4 1.8 8.9 -1.6 -0.1 -0.9 -0.7 0.4 -0.6 -3.0 1.0
Neuroticism 0.3 0.7 1.2 -1.0 -0.0 -0.9 -1.1 -0.0 -1.0 -0.9 -0.8
Chronotype (morning person) 0.3 0.8 2.5 -0.8 -0.8 0.3 0.5 -0.5 -1.6 -1.1 0.5
Hair Pigment 0.0 0.9 2.9 0.6 -0.7 0.1 0.2 1.5 -0.4 -1.0 1.7
Tanning 0.0 0.4 1.7 -0.5 -0.6 1.3 0.2 0.4 0.1 0.5 0.3
Hand grip strength (left) 0.9 2.5 6.0 -2.5 -0.3 -1.3 0.1 -1.4 0.6 -2.3 2.1
Number of treatments/medications taken 1.0 1.7 5.6 -0.7 1.6 0.4 -1.3 1.2 -1.4 -2.4 0.3
Average weekly spirits intake 1.2 1.5 8.7 0.9 1.3 0.0 -0.2 3.0 -0.0 -0.6 -0.4
Sensitivity / hurt feelings 0.3 0.5 1.6 -1.0 -0.1 -0.6 0.6 -0.6 1.3 0.1 0.5
Frequency of depressed mood in last 2 weeks 1.7 2.3 9.5 -1.4 -0.0 -3.1 -2.2 -0.1 -0.9 -1.0 0.8
Hearing difficulty/problems: Yes 0.9 1.3 3.6 -0.4 1.9 -1.3 0.9 0.4 -1.1 -1.7 0.5
Relative age of first facial hair 0.7 1.5 3.7 -0.7 -1.9 -1.0 -1.0 1.3 1.9 0.4 -0.5
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.1 -0.5 0.6 -0.5 -1.1 0.3 -0.9 -0.8 -0.1
Ever used hormone-replacement therapy (HRT) 2.1 2.7 8.5 -1.7 -0.2 1.2 -2.1 0.9 -2.9 -0.9 -1.8
Ever had hysterectomy (womb removed) 1.3 1.5 3.3 -1.8 1.8 -0.0 -1.6 1.0 -1.1 -0.8 -0.3
Systolic blood pressure, automated reading 0.6 1.7 5.0 1.1 2.2 0.5 -1.3 1.9 0.1 -0.5 1.1
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 6.2 0.9 0.8 2.5 0.3 0.2 1.6 1.5 0.0
Angina 0.3 0.4 1.2 -1.0 -1.1 0.4 -0.4 0.4 0.6 -0.2 0.3
Medication for hormone replacement therapy 0.8 0.9 2.7 0.7 1.7 -0.1 -0.0 1.6 -1.0 -0.6 -0.5
Vitamin and mineral supplements 0.8 1.1 2.7 1.2 -1.4 -0.4 0.8 1.6 -0.1 1.0 -0.8
Supplements: Zinc 1.3 1.4 4.3 -1.8 0.7 0.1 -1.3 -2.1 -0.9 -0.4 -0.8
Medication: Co-codamol 1.8 2.1 4.6 -1.6 1.6 -0.7 -2.1 0.1 -1.4 -2.1 -0.0
Medication: Metformin 0.7 1.0 3.0 0.9 1.1 1.7 -0.2 1.1 1.1 0.5 -0.7
Diabetes (father) 0.2 0.3 0.9 0.1 -1.0 -0.4 0.6 -0.3 0.7 -0.6 -0.0
Diabetes (mother) 1.5 1.9 4.8 -2.2 -0.8 0.9 -1.4 -1.4 -0.8 -2.0 0.3
Severe depression (siblings) 1.4 1.6 6.2 1.6 -0.3 1.2 1.0 2.5 0.8 0.3 -0.8
Pack years adult smoking proportion 0.9 1.4 3.6 0.7 -1.9 -0.3 0.1 -1.2 1.3 1.9 -0.1
Impedance of leg (right) 0.6 2.7 12.4 -2.1 -3.5 0.8 -1.1 -0.8 -0.7 0.8 -1.0
Leg fat-free mass (left) 0.6 3.1 10.2 1.9 3.2 0.2 1.5 1.6 0.3 -1.9 1.5
Trunk fat percentage 0.5 2.2 9.2 -1.3 0.7 0.9 -0.7 1.6 -1.1 -3.0 0.9
Hand grip strength (right) 1.0 2.6 7.1 -2.7 -0.2 -0.8 0.0 -1.2 -0.1 -2.6 2.2
Townsend deprivation index at recruitment 0.5 0.8 2.2 0.4 0.7 1.5 -0.5 0.9 -0.2 0.7 -1.3
Current tobacco smoking 0.9 1.5 5.7 0.2 -0.2 1.8 0.5 1.0 1.3 2.4 0.3
Average weekly fortified wine intake 0.4 0.4 1.0 0.2 0.7 0.6 -1.0 0.3 -1.0 -0.0 -0.7
Maternal smoking around birth 1.1 1.5 6.9 -1.2 -0.4 0.3 -2.6 0.6 -1.7 -0.4 -0.4
Fed-up feelings 1.4 2.6 7.6 -2.8 0.0 -1.6 -2.4 -1.2 -0.9 -1.7 0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.7 -0.4 0.6 -1.1 -0.8 0.6 0.0 -1.0 1.3
Relative age voice broke 1.7 2.6 6.5 -1.9 -1.8 0.2 -2.4 0.6 0.1 2.5 -1.0
Taking other prescription medications 2.9 4.5 8.9 -1.1 3.0 -0.7 -2.7 2.3 -1.7 -2.9 -1.4
Age when periods started (menarche) 0.6 1.4 3.8 0.8 -1.3 -1.7 0.4 0.0 1.4 1.9 -0.2
Bilateral oophorectomy (both ovaries removed) 1.1 1.3 3.6 -1.9 1.2 0.3 -1.7 0.2 -1.0 -1.0 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 2.5 -0.8 0.8 -0.6 -1.6 0.9 -0.6 -1.6 -0.2
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 6.6 0.2 0.1 1.1 -0.1 0.3 -2.6 0.2 -0.9
Qualifications: CSEs or equivalent 0.6 0.8 2.7 -0.1 0.9 -1.3 0.7 0.6 0.1 -1.7 0.5
Serious illness, injury or assault to yourself 0.2 0.2 0.6 -0.2 0.2 -0.6 0.3 -0.8 -0.0 -0.7 -0.6
High blood pressure 0.6 1.6 3.6 -1.9 1.5 1.3 -1.5 0.0 -0.7 -0.6 1.3
Hayfever, allergic rhinitis or eczema 1.2 2.6 6.2 -0.6 1.6 1.0 -2.5 0.8 -2.3 0.1 -2.1
Multivitamins +/- minerals 0.7 0.9 2.0 -0.9 1.4 0.8 -0.9 -0.9 -0.0 -0.9 1.4
Stomach or abdominal pain in last month 0.9 1.1 5.4 -2.3 -0.4 -0.1 -1.2 -1.2 -0.3 -0.2 0.4
Supplements: Glucosamine 0.6 0.7 2.9 -0.3 -0.4 -1.2 -0.6 -0.3 -0.8 -1.7 0.2
Diverticular disease/diverticulitis (self-reported) 1.9 2.3 8.8 -3.0 -1.0 0.4 -1.9 -0.6 -1.0 -1.8 0.6
Medication: Atenolol 0.5 0.6 1.2 -1.0 -0.8 -0.4 0.3 -1.1 0.7 -0.8 0.8
Medication: Levothyroxine sodium 2.3 3.8 22.7 -1.9 0.2 -1.1 -1.4 0.0 -0.7 -4.8 0.7
Sitting height 0.4 3.1 18.7 -0.8 1.0 -1.0 0.2 1.0 -0.6 -4.3 1.5
Chronic bronchitis/emphysema (father) 1.1 1.3 2.7 1.5 -0.1 -1.3 1.3 1.3 0.6 -1.6 0.0
High blood pressure (mother) 1.0 1.3 5.1 -0.3 1.8 -0.5 -0.7 0.2 -2.3 -1.1 -0.0
Body mass index (BMI) 0.6 2.5 7.6 0.0 2.1 0.8 0.2 1.4 0.2 -2.8 2.3
Impedance of leg (left) 0.5 2.6 9.5 -2.4 -3.1 0.6 -1.4 -0.4 -1.3 0.2 -1.1
Leg predicted mass (left) 0.6 3.2 10.5 2.0 3.2 0.3 1.7 1.6 0.4 -1.8 1.5
Trunk fat mass 0.6 2.7 10.3 -0.7 1.8 0.6 -0.2 2.1 -0.7 -3.2 1.6
Waist circumference 0.8 2.8 8.9 -0.6 2.1 1.2 -0.3 2.0 -0.3 -3.0 1.7
Number of incorrect matches in round 0.7 1.2 3.1 0.8 0.8 1.3 0.7 1.3 -1.8 -0.8 0.6
Past tobacco smoking 1.2 2.1 8.7 -1.7 -0.5 0.7 -0.7 -3.0 -1.6 -0.0 -1.4
Alcohol usually taken with meals 0.6 1.0 3.2 1.3 0.0 0.4 1.8 -0.4 1.3 0.6 0.9
Nervous feelings 0.2 0.4 1.2 -0.5 -0.4 -1.1 -1.0 -0.2 -0.0 0.3 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.5 -0.4 -0.7 -0.2 -0.4 -0.3 -0.4 0.5 0.7
Hearing difficulty/problems with background noise 0.3 0.6 3.3 0.8 1.8 0.4 -0.2 0.3 -0.5 -0.1 0.3
Hair/balding pattern: Pattern 2 1.3 1.6 3.1 0.4 1.8 1.0 1.3 1.6 0.7 -1.1 1.6
Had menopause 1.3 1.6 4.2 -0.1 2.0 0.9 -1.0 1.9 -1.9 0.5 0.2
Had other major operations 1.4 1.7 5.0 -0.9 -1.1 -0.8 -1.2 1.8 -1.2 -2.2 -0.4
Forced vital capacity (FVC) 0.3 1.2 4.8 -0.1 0.8 -1.0 0.8 0.8 0.1 -2.2 1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.3 3.2 -1.2 1.1 0.3 -1.6 0.3 -1.1 -1.8 -0.3
Ever unenthusiastic/disinterested for a whole week 0.9 1.2 3.7 -0.9 -1.6 -0.7 -0.2 0.4 1.9 -0.8 0.9
Qualifications: None of the above 0.5 1.2 2.6 1.1 -0.4 1.5 1.5 0.4 0.7 0.3 1.6
Financial difficulties in last 2 years 0.5 0.7 3.6 0.3 -1.9 -0.0 0.0 -0.2 0.0 0.9 -0.9
Mouth/teeth dental problems 0.7 1.0 2.7 0.1 1.6 1.2 -0.6 0.6 -1.2 -0.3 -1.4
Heart attack 0.8 1.0 3.6 -0.5 -1.9 -0.4 0.3 -1.0 1.5 0.7 0.6
Allergy 1.2 2.8 6.8 0.4 -1.9 0.0 2.6 -1.2 2.0 -0.5 2.5
Pain all over the body in last month 0.6 0.7 2.3 -0.1 -0.0 0.1 0.3 1.0 0.6 -1.3 1.5
Diabetes (self-reported) 0.9 1.5 4.9 1.2 0.9 2.2 0.2 1.4 0.5 0.9 -1.2
Hayfever/allergic rhinitis (self-reported) 1.5 2.0 5.7 -0.7 1.1 -0.2 -2.0 -0.3 -2.0 0.7 -2.4
Medication: Ramipril 1.0 1.2 5.1 -1.1 0.5 -0.9 -2.3 0.3 -0.7 -1.0 -1.0
Medication: Simvastatin 0.2 0.3 0.8 -0.6 -0.2 0.2 -0.4 -0.3 -0.3 -0.7 -0.9
Fluid intelligence score 0.4 0.7 2.4 -1.4 -0.5 1.0 0.4 -0.0 -0.0 -1.5 0.2
Illnesses of siblings 0.9 1.2 2.7 1.0 -1.6 -0.7 -0.3 -0.6 0.6 1.6 -1.5
Neuroticism score 0.5 1.0 2.1 -1.4 0.2 -1.3 -1.5 -0.5 -0.9 -1.0 0.1
Weight 0.8 3.9 9.7 0.5 3.0 0.8 0.6 2.4 -0.1 -3.1 2.2
Impedance of arm (right) 0.7 3.4 10.3 -1.3 -2.4 -1.0 -1.4 -1.7 -0.7 1.8 -3.2
Arm fat percentage (right) 0.4 1.4 6.2 -0.3 1.4 0.3 -0.2 1.2 -0.5 -2.5 1.0
Trunk fat-free mass 0.8 4.8 12.8 2.4 3.6 0.8 2.0 2.5 0.4 -2.2 2.1
Hip circumference 0.4 1.8 5.4 0.5 2.3 1.2 -0.4 1.5 -0.7 -1.7 1.1
Time employed in main current job 2.2 2.5 6.6 -1.5 1.3 -2.1 -2.6 -0.4 -1.5 -1.6 -0.2
Alcohol intake versus 10 years previously 0.7 1.1 3.8 0.4 0.1 1.9 0.6 -0.5 0.9 1.8 0.4
Father’s age at death 0.7 1.0 2.0 0.8 -0.2 1.4 0.6 -0.9 -0.9 1.3 -1.2
Worrier / anxious feelings 0.3 0.6 3.6 0.3 -0.6 -0.5 -0.4 -0.3 0.2 1.9 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.2 -0.5 -0.1 -1.1 -0.7 -0.9 0.5 0.1 -0.3
Falls in the last year 1.3 1.7 8.0 0.9 -1.8 1.1 0.2 2.8 -0.1 -0.7 -0.3
Hair/balding pattern: Pattern 3 0.9 1.3 5.7 0.2 -2.4 -0.8 -0.9 -0.6 -0.7 0.8 -1.4
Number of live births 1.2 1.7 7.2 -1.6 0.5 -1.1 -1.3 0.1 0.6 -0.1 2.7
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 4.3 0.1 0.8 -2.0 0.7 -0.3 0.3 -2.1 1.2
Pulse rate 0.3 0.5 2.7 0.2 1.6 0.6 -0.6 0.3 -0.1 0.2 0.3
Happiness 0.7 0.9 2.7 -0.3 0.4 -0.0 -1.4 1.6 0.3 -0.9 1.1
Noisy workplace 0.7 0.9 3.3 -0.0 0.7 -1.8 -1.6 0.3 -0.7 -0.5 0.3
Qualifications: A levels/AS levels or equivalent 0.8 1.7 6.7 -2.6 0.1 -1.4 -1.5 -1.1 0.0 -0.4 -1.2
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.3 4.8 0.8 1.3 -0.7 -0.3 0.5 -2.2 1.2 -1.0
Mouth/teeth dental problems: Dentures 0.4 0.6 3.0 0.2 0.2 -0.6 0.3 0.2 1.2 -0.2 1.7
Asthma 0.9 1.7 4.1 -0.1 1.2 0.7 -1.6 1.5 -2.0 0.2 -1.6
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.2 3.3 1.8 -0.4 -1.0 0.7 1.4 -0.6 -1.5 0.1
Medication: Cholesterol lowering 0.6 1.0 3.3 -1.2 -1.2 -0.8 -1.8 -0.0 -0.2 -0.8 -0.8
Depression (self-reported) 0.7 0.8 2.3 -0.6 -0.5 -0.7 -0.8 0.9 1.2 0.4 1.5
Medication: Lansoprazole 1.7 2.0 8.1 -1.5 1.0 -0.2 -1.1 1.0 0.3 -2.9 1.4
Prospective memory result 0.9 1.1 2.2 1.2 1.3 1.5 0.1 0.6 -1.1 1.5 0.0
Lung cancer (father) 0.5 0.6 1.3 -0.4 0.7 0.1 -1.0 1.1 -1.0 0.7 0.5
Illnesses of mother 2.0 2.5 5.4 1.6 -1.2 1.7 1.1 -0.3 2.2 2.3 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 2.1 -0.7 0.0 -1.3 -0.3 -0.5 0.1 -1.4 0.7
Pulse wave Arterial Stiffness index 1.2 1.4 3.0 -1.7 -1.0 0.6 -0.8 0.9 -1.5 -1.5 -1.0
Impedance of arm (left) 0.9 4.3 11.5 -1.5 -2.8 -1.1 -1.8 -1.7 -0.9 2.1 -3.4
Arm fat mass (right) 0.6 2.6 8.5 0.2 2.2 0.5 0.2 2.0 -0.2 -2.9 1.8
Trunk predicted mass 0.9 5.0 12.6 2.5 3.5 0.8 2.2 2.5 0.5 -2.2 2.1
Standing height 0.2 1.7 5.3 0.8 1.9 0.0 0.9 2.3 -0.5 -1.6 0.4
Length of working week for main job 0.3 0.3 1.5 0.1 -0.3 -0.1 0.2 -1.2 -0.6 -0.3 0.3
Exposure to tobacco smoke at home 0.8 0.8 1.8 1.1 0.3 1.4 1.3 0.7 0.8 0.8 0.1
Breastfed as a baby 0.6 0.7 1.9 -0.7 0.6 0.8 -0.9 -0.0 -0.9 -1.4 -0.9
Tense / ‘highly strung’ 0.4 0.6 1.8 -0.4 1.3 0.3 -0.7 -0.7 -1.3 0.7 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 8.1 0.8 -0.6 -0.3 -0.8 2.8 1.6 -0.5 0.0
Hair/balding pattern: Pattern 4 0.4 1.0 4.2 -0.6 0.3 0.2 1.5 -0.1 0.9 0.1 2.1
Birth weight of first child 0.8 1.4 6.0 -0.0 1.1 -0.8 -0.1 1.6 -0.8 -2.5 -0.5
Peak expiratory flow (PEF) 0.7 1.6 2.9 0.1 -1.6 -1.7 0.7 -1.7 0.9 -0.7 1.5
Pulse wave reflection index 1.9 2.4 5.6 -2.4 -1.4 -0.6 -2.2 0.0 -1.6 -1.3 -1.4
Ever highly irritable/argumentative for 2 days 1.2 1.5 4.5 -1.3 -2.1 -0.4 -1.3 -1.0 1.1 -0.1 1.3
Loud music exposure frequency 2.3 2.5 6.5 1.2 2.5 1.7 0.2 2.1 -0.6 -1.9 0.9
Qualifications: O levels/GCSEs or equivalent 2.7 4.2 10.4 -2.0 2.1 -1.4 -2.8 0.0 -2.2 -0.7 -3.2
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.2 0.5 -0.5 -0.7 -0.5 0.3 0.6 1.1 -1.0
Blood clot in the leg (DVT) 1.4 1.8 6.1 -0.1 -0.4 -2.3 0.1 0.1 2.5 1.5 0.3
Medication: Paracetamol 0.8 1.3 7.7 0.5 0.4 0.5 -0.5 1.1 -0.1 2.8 0.6
Headache pain in last month 0.6 1.0 1.9 -1.0 0.5 -0.3 -0.8 0.8 -1.4 -1.1 1.3
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 5.6 1.8 0.4 1.7 2.4 0.4 -0.0 1.4 0.4
Glaucoma (self-reported) 0.6 0.7 1.7 -1.1 0.8 1.1 -1.3 0.2 0.3 -0.5 -0.7
Gout (self-reported) 0.6 0.9 2.7 -0.7 -0.8 -0.4 -1.6 1.0 -1.1 0.1 -0.9
Hypothyroidism/myxoedema (self-reported) 1.7 3.2 18.2 -1.5 -0.4 0.1 0.7 -0.4 0.5 -4.3 2.1
Medication: Amlodipine 1.2 1.6 6.5 -2.5 -1.1 0.0 -1.1 -1.7 -0.5 -0.8 -0.6
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.9 -0.4 -0.0 -0.4 -0.8 0.4 0.3 0.9 -1.7
Birth weight 0.8 1.8 4.8 1.6 -1.1 -0.8 2.2 1.6 1.4 0.4 -0.6
Chronic bronchitis/emphysema (mother) 0.1 0.2 0.5 -0.1 0.2 -0.0 -0.1 -0.2 -0.7 -0.5 -0.7
High blood pressure (siblings) 1.2 1.8 5.0 -1.7 1.7 0.5 -0.2 0.3 -0.7 -2.2 1.6
Forced vital capacity (FVC), Best measure 0.1 0.4 1.9 -0.5 0.3 -0.6 0.0 0.4 -0.2 -1.4 0.6
Body fat percentage 0.5 2.1 8.6 -1.1 0.8 0.9 -0.6 1.7 -1.1 -2.9 1.2
Leg fat percentage (right) 0.6 2.0 6.2 -1.0 0.6 1.3 -0.4 1.6 -0.8 -2.5 1.9
Arm fat-free mass (right) 0.8 4.1 8.4 1.5 2.9 0.8 1.5 2.3 0.4 -2.7 2.5
Exposure to tobacco smoke outside home 0.2 0.3 0.7 0.2 -0.1 -0.6 0.3 -0.5 0.8 0.8 -0.3
Comparative body size at age 10 0.3 0.9 4.3 0.0 2.1 -0.2 0.4 0.1 -1.0 -1.2 0.5
Number of full brothers 0.5 0.6 1.7 -0.3 0.7 0.7 -0.5 0.8 -0.9 -1.3 -0.3
Worry too long after embarrassment 0.2 0.4 1.5 -1.2 -0.5 -0.4 -0.4 -1.0 0.4 -0.3 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.1 0.3 0.4 -0.3 0.1 1.1 1.4 -0.2 0.4
Wheeze or whistling in the chest in last year 1.1 1.9 6.1 -2.5 -1.7 -0.3 -1.0 -0.2 -1.7 -1.5 0.4
Number of children fathered 1.5 1.7 6.1 0.6 2.2 -2.5 -0.3 0.8 -0.2 -1.2 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.9 2.8 0.7 0.8 -0.1 1.7 0.6 0.3 -1.6 0.2
Age at first live birth 0.5 0.9 2.5 0.6 -0.8 1.6 1.2 -0.3 0.8 0.6 1.1
Pulse wave peak to peak time 1.1 1.2 3.0 1.7 1.2 -0.6 0.9 -1.0 1.3 1.0 0.8
Health satisfaction 1.2 1.5 4.1 -0.1 0.2 0.8 -1.6 1.6 -1.5 -2.0 0.4
Shortness of breath walking on level ground 1.2 1.4 3.1 -1.7 -0.0 1.5 -1.4 0.4 -1.0 -1.4 0.9
Qualifications: College or University degree 0.1 0.4 1.5 -0.6 -1.2 -0.2 -0.1 -0.9 -0.3 -0.2 -0.8
Eye problems/disorders: None of the above 1.6 1.9 8.9 -0.2 0.9 -3.0 -1.3 0.6 -1.5 0.4 -0.8
Mouth/teeth dental problems: Loose teeth 1.1 1.3 2.7 0.5 -1.6 -1.3 -0.1 -0.8 1.1 1.4 1.4
Emphysema/chronic bronchitis 1.0 1.1 2.9 -1.7 -1.2 -0.5 -1.4 -0.4 -0.6 0.4 -1.2
Medication for pain relief, constipation, heartburn 1.0 1.7 5.3 -0.8 -1.6 -1.3 0.7 -2.3 1.6 -0.4 -0.3
Neck or shoulder pain in last month 0.8 1.2 3.7 -0.6 -1.5 -0.2 -0.3 -0.8 1.4 1.9 0.7
Medication: Blood pressure 0.6 1.1 3.6 -1.9 0.6 -1.0 -1.5 -1.0 0.2 -0.9 -0.1
Angina (self-reported) 0.3 0.4 1.3 -1.2 -1.1 0.3 -0.6 0.6 0.2 -0.5 0.1
Migraine (self-reported) 1.8 2.3 6.7 -1.4 1.6 -1.2 -0.5 1.1 -0.2 -2.0 2.6
Medication: Ibuprofen 0.8 1.0 3.0 1.7 -0.9 -0.6 0.9 0.9 -0.9 -1.1 0.0
Medication: Allopurinol 1.1 1.4 5.2 -1.2 -0.5 -1.3 -2.3 1.0 -1.2 -0.8 0.2
Medication: Omeprazole 0.7 0.8 2.9 -1.7 -0.4 0.4 -0.6 0.7 -0.2 -1.6 0.3
Medication: Seretide 50 evohaler 0.9 1.0 4.2 -0.1 -0.4 1.0 -0.4 0.7 -2.0 -0.5 -1.3
Mean time to correctly identify matches 0.5 0.9 4.7 1.1 -0.3 0.4 -0.3 -0.5 0.0 2.2 -1.1
Heart disease (mother) 1.0 1.2 5.6 -1.0 -1.1 -2.4 -0.5 -0.3 -0.7 -0.9 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 3.8 0.1 -1.8 0.8 0.8 0.9 1.1 0.6 2.0
Whole body fat mass 0.6 2.5 8.6 -0.3 1.8 0.8 -0.1 2.1 -0.5 -2.9 1.7
Leg fat mass (right) 0.7 2.7 8.2 -0.2 1.6 1.1 0.3 2.1 -0.5 -2.9 2.1
Arm predicted mass (right) 0.8 4.1 7.7 1.5 2.7 1.0 1.5 2.3 0.3 -2.8 2.6
Pulse rate, automated reading 0.4 1.4 5.5 1.1 1.4 2.4 0.5 1.4 -0.2 -0.0 0.6
Alcohol intake frequency. 0.3 0.7 3.0 0.4 0.5 0.8 0.7 -0.4 -0.3 1.7 0.6
Comparative height size at age 10 0.4 2.2 4.8 1.4 1.4 2.2 0.7 2.1 -1.5 -1.1 -0.7
Number of full sisters 0.2 0.3 0.7 0.2 0.5 0.7 0.1 0.6 -0.8 -0.5 0.4
Suffer from ‘nerves’ 0.4 0.6 3.0 0.8 0.9 0.0 0.1 1.7 0.3 -0.4 0.3
Overall health rating 0.1 0.3 1.5 -0.5 0.1 0.2 -1.2 -0.0 -0.3 -0.5 -0.1
Chest pain or discomfort 0.9 1.3 2.7 -1.3 -1.6 -0.4 -1.6 1.6 -0.4 -0.9 0.3
Had major operations 0.6 0.7 2.6 0.4 -0.1 0.5 0.5 0.4 0.8 1.1 -1.6
Age at last live birth 1.4 2.0 4.2 2.0 -0.3 1.3 1.8 1.0 1.4 1.6 1.1
Family relationship satisfaction 1.2 1.5 3.8 1.2 -1.1 1.6 1.1 0.2 1.1 1.9 0.4
Leg pain on walking 0.6 0.8 2.9 -1.7 0.2 0.4 -1.1 -1.3 0.1 -0.1 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.7 0.3 1.6 0.1 -0.7 -0.8 -0.1 0.1 -1.4
Commuting to job workplace: Car/motor vehicle 2.7 3.1 8.5 0.4 -1.8 1.8 2.1 -0.6 2.0 2.9 1.2
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.4 -0.6 0.4 0.2 -1.1 -1.2 0.0 -0.9 -0.5
Medication: Aspirin 0.8 1.1 3.5 -0.1 1.2 0.5 0.0 1.6 -0.8 -1.9 -0.5
Supplements: Vitamin C 0.5 0.6 1.4 0.2 1.1 0.6 -0.3 -1.0 -0.1 0.9 -1.2
Knee pain experienced in last month 1.3 2.0 4.6 1.4 -0.6 2.1 2.1 0.3 1.1 1.4 1.1
Hypertension (Self-reported) 0.5 1.3 3.2 -1.8 1.4 1.1 -1.4 0.2 -0.4 -0.7 1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.4 5.1 11.2 -3.2 0.5 0.8 -3.1 1.5 -2.5 -3.3 -1.0
Illnesses of father: Heart disease 1.4 2.0 9.2 0.5 -1.3 1.2 0.6 -0.7 1.3 3.0 -0.9
Illnesses of siblings: Diabetes 0.9 1.1 2.0 0.3 1.1 1.0 1.3 1.4 -0.3 -1.3 1.1
Smoking status: Previous 1.3 1.9 7.2 2.0 0.5 -0.4 0.6 2.7 1.3 0.8 1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 3.1 -0.2 1.8 0.6 0.8 -0.5 -0.5 -1.0 0.4
Whole body fat-free mass 0.8 4.3 11.9 2.2 3.5 0.6 1.9 2.2 0.4 -2.1 2.0
Leg fat-free mass (right) 0.6 3.2 11.8 1.9 3.4 -0.0 1.5 1.6 0.3 -2.0 1.3
Arm fat percentage (left) 0.3 1.2 5.1 -0.3 1.4 0.5 -0.4 1.1 -0.8 -2.2 0.7
Average weekly red wine intake 0.4 0.6 1.5 -0.2 0.9 0.4 -1.0 0.7 -1.2 -0.2 -0.9
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.8 0.8 -0.9 -0.6 0.3 0.4 0.6 1.3 0.3
Mood swings 1.2 2.2 5.5 -0.9 0.9 -1.4 -2.3 -0.8 -2.1 -1.7 -0.2
Loneliness, isolation 0.6 0.9 2.7 -1.2 -0.3 -0.4 -1.5 0.1 0.1 -1.6 0.4
Long-standing illness, disability or infirmity 0.5 0.8 1.8 -0.4 0.7 0.6 -1.3 1.3 -0.5 -1.0 0.5
Ever had bowel cancer screening 0.4 0.5 1.7 -1.3 0.4 0.2 -0.9 0.9 -0.2 -0.4 0.4
Diabetes diagnosed by doctor 0.7 1.2 3.6 0.7 1.1 1.9 0.3 1.8 0.3 -0.2 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 2.6 0.6 0.3 -1.6 0.6 -0.5 0.9 -0.6 0.6
Friendships satisfaction 0.4 0.5 2.3 -0.2 0.1 1.5 0.3 -0.7 0.5 0.9 0.6
Qualifications: nursing, teaching 0.4 0.7 1.9 0.3 1.4 -0.2 -0.0 1.2 -0.3 0.6 -1.2
Commuting to job workplace: Walk 0.5 0.6 1.8 0.5 1.1 0.5 0.9 1.3 0.4 -0.4 -0.2
Eye problems/disorders: Cataract 2.6 3.0 8.1 1.6 -0.2 2.8 1.6 -0.3 2.2 1.8 1.5
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 3.9 -1.2 -2.0 -1.6 -0.8 -0.9 1.1 -0.1 0.4
Medication for cholesterol 1.5 2.2 6.3 0.6 -2.3 -2.5 0.4 -1.2 1.3 1.5 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 4.3 -1.3 0.5 -0.0 -0.9 -0.0 -1.1 -2.1 1.4
Back pain experienced in last month 1.2 1.8 3.9 1.2 1.8 2.0 -1.0 0.7 -1.5 0.0 -1.4
Mineral and other dietary supplements 0.3 0.4 1.2 -0.5 0.2 -1.1 -0.5 0.4 -0.6 -0.7 0.2
Breast cancer (self-reported) 1.0 1.2 2.9 1.7 1.0 -0.4 1.6 0.9 0.5 0.0 1.4
Asthma (self-reported) 0.7 1.4 3.0 0.2 0.8 1.1 -1.2 1.5 -1.7 0.7 -1.6
Osteoporosis (self-reported) 0.9 1.1 3.8 -0.7 -0.8 -0.0 -0.9 0.4 1.9 -0.3 1.6
Osteoarthritis (self-reported) 1.1 1.5 6.9 -0.2 -0.8 1.8 0.6 0.3 0.4 0.7 2.6
Medication: Aspirin 0.8 1.1 3.2 -0.2 0.8 0.8 -0.1 1.2 -1.3 -1.8 -0.8
Medication: Gliclazide 0.2 0.2 0.6 -0.4 -0.0 0.8 -0.5 0.7 0.5 0.4 -0.2
Illnesses of father: None of the above (group 1) 0.2 0.2 0.9 0.1 0.0 0.2 -0.5 -0.4 -0.9 -0.6 0.3
Smoking status: Current 0.6 0.9 2.8 -0.2 -0.3 1.7 0.3 0.5 1.2 1.5 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 7.0 -2.0 0.6 -0.8 -0.8 0.1 -1.6 -2.6 0.8
Whole body water mass 0.8 4.5 12.7 2.3 3.6 0.6 1.9 2.3 0.4 -2.2 2.0
Leg predicted mass (right) 0.6 3.3 11.9 1.9 3.5 -0.0 1.5 1.6 0.3 -2.1 1.3
Arm fat mass (left) 0.6 2.5 8.6 0.2 2.2 0.7 0.2 1.8 -0.3 -2.9 1.7
Number of self-reported non-cancer illnesses 1.7 3.0 10.3 -1.7 1.1 0.8 -3.2 1.7 -1.9 -1.3 -0.6
Average weekly champagne plus white wine intake 0.5 0.7 2.0 -0.5 0.7 0.7 -1.1 0.6 -0.6 -1.4 0.8
Miserableness 1.1 1.9 3.5 -1.9 -1.5 -1.0 -1.8 -1.4 -0.7 -1.5 -0.2
Guilty feelings 0.2 0.3 0.8 0.4 -0.9 -0.3 0.6 -0.1 0.9 0.6 0.4
Wears glasses or contact lenses 0.5 0.6 1.7 -0.6 -1.3 -0.3 -0.4 0.4 -1.2 -0.5 0.5
Ever taken oral contraceptive pill 0.6 0.6 1.5 1.0 -1.1 -1.2 -0.0 0.9 -0.4 -0.3 -0.3
Hearing aid user 1.4 1.6 3.4 -1.4 1.8 -1.5 -1.2 0.4 -1.2 -0.9 0.9
Mother’s age at death 1.3 1.6 4.6 0.6 -1.9 0.3 0.7 0.7 1.9 2.1 -0.0
Financial situation satisfaction 0.6 0.8 3.8 0.9 -2.0 -0.4 0.1 -0.4 0.3 -0.4 1.1
Tinnitus: Yes, now most or all of the time 1.0 1.2 3.6 -1.9 1.0 -0.2 -0.6 -1.6 -1.2 -0.7 0.8
Commuting to job workplace: Public transport 0.9 1.1 3.0 -0.4 -0.3 -1.1 -0.9 -0.4 -1.7 -0.4 -1.7
Eye problems/disorders: Glaucoma 1.0 1.1 3.3 -1.5 1.0 0.7 -1.8 0.2 -0.6 -0.5 -1.1
Medication: Blood pressure 1.4 2.7 6.9 -1.7 2.6 2.5 -1.2 -0.1 -1.6 -0.6 0.8
Pain type(s) experienced in last month: Hip pain 1.3 1.6 5.0 1.8 -1.4 1.1 0.4 1.0 0.8 2.2 -0.2
Supplements: Fish oil (including cod liver oil) 0.6 0.8 2.9 1.0 0.3 1.1 0.3 -0.5 0.2 1.7 -1.1
High cholesterol (Self-reported) 0.3 0.6 1.6 -0.9 -0.2 1.3 -0.6 0.3 0.1 -1.2 0.4
Medication: Bendroflumethiazide 0.5 0.8 4.9 -0.2 2.2 0.5 0.0 0.2 -0.1 -0.9 0.6
Medication: Paracetamol 0.5 0.8 3.7 -0.3 -0.4 -0.3 -0.7 0.9 0.3 1.9 0.9
Medication: Lisinopril 2.6 3.4 22.8 -0.6 4.8 0.1 -0.5 0.7 -1.6 -0.5 0.8
Medication: Atorvastatin 1.6 2.0 6.3 -2.0 -0.1 0.5 -1.0 0.6 0.6 -2.5 1.9
Illnesses of father: High blood pressure 0.7 0.8 3.0 -1.7 0.6 -0.5 -1.2 -0.6 -1.0 -0.3 0.2
Alcohol drinker status: Never 1.6 1.9 4.8 -1.4 -2.2 -1.4 -1.0 -1.8 -1.3 -0.1 -0.9
Ever smoked 1.1 2.0 11.0 1.5 0.7 -0.6 0.4 3.3 0.9 0.5 0.6
Basal metabolic rate 0.8 4.3 12.0 1.9 3.5 0.7 1.6 2.2 0.3 -2.5 2.1
Leg fat percentage (left) 0.8 2.8 9.0 -1.2 0.9 1.3 -0.5 1.9 -1.0 -3.0 2.1
Arm fat-free mass (left) 1.0 5.2 11.8 1.7 3.4 1.1 1.5 2.8 0.3 -3.1 2.4
Number of operations (self-reported) 0.7 1.1 4.3 -0.9 -1.4 -0.6 -1.0 2.1 -0.1 -0.4 -0.0
Average weekly beer plus cider intake 0.5 0.8 1.6 -0.5 1.3 0.8 -1.0 0.1 -0.9 1.0 -0.9
Irritability 0.8 1.3 4.5 -0.9 2.1 -0.1 -1.6 -0.4 -1.5 -0.2 -0.2
Risk taking 0.4 0.5 2.7 -0.9 0.5 0.2 -0.4 -1.6 0.2 0.3 -0.3
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.4 1.6 0.6 0.1 0.7 0.8 0.5 -0.8 1.2
Fractured/broken bones in last 5 years 2.2 2.9 9.2 3.0 -0.0 1.0 1.8 1.8 1.9 1.5 0.5
Age started oral contraceptive pill 1.2 1.6 5.0 -0.1 1.1 -0.9 -1.6 0.3 -2.2 1.4 -1.0
Diastolic blood pressure, automated reading 0.5 1.5 4.3 0.4 1.2 1.4 -1.7 2.1 -0.6 -0.8 0.1
Ever depressed for a whole week 0.9 1.1 3.0 -1.7 -1.0 -0.3 -0.8 0.3 0.8 -1.4 1.2
Unable to work because of sickness or disability 0.4 0.5 2.6 -0.7 0.1 0.7 0.7 -0.0 1.6 0.1 0.3
Commuting to job workplace: Cycle 0.7 0.8 2.4 1.3 -1.3 0.2 1.6 0.3 -0.9 0.2 -0.3
Myopia 0.4 0.6 2.0 0.6 1.4 -0.5 -0.0 0.9 -1.0 -0.5 -0.7
Vascular/heart problems diagnosed by doctor 0.5 1.2 3.6 1.9 -1.1 -1.3 1.4 0.5 0.4 0.2 -1.0
Cholesterol lowering medication 0.7 1.0 4.1 -0.9 1.0 2.0 0.2 0.3 0.0 -0.9 1.1
Medication: Omeprazole (e.g. Zanprol) 1.1 1.4 4.0 -1.6 -0.3 0.2 -0.6 1.6 -1.2 -2.0 -0.2
Pain experienced in last month 0.5 0.8 2.7 -0.7 -0.4 -1.6 0.4 -0.8 -0.2 -0.5 -1.6
Supplements: Calcium 0.3 0.3 0.9 0.1 -0.9 0.5 -0.3 -0.3 -0.2 1.0 -0.4
Basal cell carcinoma (self-reported) 0.9 1.1 2.9 1.2 1.7 -1.0 0.3 0.5 -1.3 -0.3 -1.3
Heart attack/myocardial infarction (self-reported) 1.0 1.2 4.7 -0.6 -2.2 -0.2 0.4 -1.2 1.5 0.7 0.6
Deep venous thrombosis (DVT) (self-reported) 1.3 1.7 5.6 0.1 -0.6 -2.2 -0.1 0.2 2.4 1.6 0.1
Heart disease (siblings) 0.2 0.2 0.5 -0.7 0.3 0.1 -0.1 -0.1 -0.6 -0.4 -0.6
Alcohol drinker status: Previous 0.6 0.7 3.4 -0.3 0.8 1.8 0.1 -0.1 -0.7 0.8 0.6
Pack years of smoking 0.7 1.1 3.9 0.2 -2.0 -0.3 -0.1 -1.1 1.2 1.3 -0.3
Impedance of whole body 0.8 4.1 12.5 -2.4 -3.5 -0.2 -2.0 -1.3 -1.1 1.0 -2.5
Leg fat mass (left) 0.8 3.0 8.9 -0.3 1.8 1.2 0.2 2.3 -0.6 -3.0 2.2
Arm predicted mass (left) 1.0 5.1 10.7 2.0 3.3 1.2 1.8 2.8 0.4 -2.8 2.5