Hub : Genes

C14orf1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Bladder Urothelial Carcinoma 0.104 0.049 4.3e-03 0.046 0.016 0.019 NA 0.038 8.4e-05 1.5e-02 8.6e-03 NA 0.00036
2 TCGA Thyroid Carcinoma 0.184 0.070 3.8e-05 0.030 0.040 0.067 NA 0.024 6.5e-04 8.2e-05 4.3e-07 NA 0.00180

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.1 0.2 0.4 0.1 -0.6
Bipolar Disorder or Schizophrenia 0.1 0.2 0.3 0.6 -0.4
Depressed Affect (Nagel 2018) 0.4 0.8 1.3 0.5 -1.1
Depression (Nagel 2018) 0.2 0.4 0.7 -0.8 -0.1
Intelligence (Savage-Jansen 2018) 1.2 3.8 7.0 0.8 -2.6
Neuroticism (Nagel 2018) 0.2 0.5 0.7 0.6 -0.8
Schizophrenia (2018) 0.1 0.2 0.5 0.7 -0.1
Schizophrenia vs Biploar Disorder 0.2 0.3 0.4 0.6 -0.5
Worry (Nagel 2018) 0.4 0.9 1.1 -0.8 -1.0
Alzheimer’s Disease (in mother) 0.2 0.3 0.5 -0.1 -0.7
Alzheimer’s Disease (in father) 0.1 0.1 0.1 -0.1 -0.3
Alzheimer’s Disease (including proxy) 0.6 0.8 1.3 -0.6 -1.1
Crohns Disease (2017) 0.3 0.7 1.0 1.0 -0.7
Irritable Bowel Disease (IBD) 0.5 1.1 1.7 1.3 -0.7
Ulcerative Colitis (UC) 0.4 0.7 1.3 1.1 0.1
Major Depression (MDD) 0.5 0.6 1.3 -0.1 1.1
Reaction Time 1.0 2.0 3.8 -2.0 0.4
Verbal and Numeric Reasoning (VNR) 0.7 1.7 2.2 1.5 -1.1
Breast Cancer 0.6 1.3 2.3 -1.5 -0.6
Ovarian Cancer 0.2 0.2 0.3 0.5 -0.3
Prostate Cancer 0.1 0.2 0.3 -0.5 0.3
Age at First Birth 0.2 0.3 0.3 -0.5 -0.6
Bipolar Disorder (2011) 0.4 0.4 0.7 0.4 -0.8
Body Mass Index (BMI) (2010) 0.7 1.0 1.0 -1.0 1.0
Coronary Artery Disease (CAD) 1.9 2.3 4.6 0.1 -2.1
Crohns Disease (2012) 0.6 1.0 1.1 1.0 -0.9
Mean Putamen Volume 0.1 0.1 0.1 -0.1 -0.4
Fasting Glucose 3.4 4.0 7.1 2.7 1.0
HbA1C 1.2 1.3 2.1 1.5 0.7
HDL Cholesterol 0.6 1.1 1.3 -0.9 1.2
LDL Cholesterol 0.5 0.7 1.5 1.2 -0.2
Lupus 0.9 1.4 1.8 1.4 -1.0
Neuroticism (2016) 2.1 3.0 4.5 2.1 -1.3
Primary Biliary Cirrhosis 2.9 4.2 6.9 2.6 -1.2
Rheumatoid Arthritis 0.1 0.2 0.3 -0.3 -0.6
Schizophrenia (2014) 0.4 0.9 1.5 1.2 -0.5
Triglycerides 0.0 0.1 0.1 0.1 0.3
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.1 0.2 0.4
Ulcerative Colitis 2.2 3.2 6.4 2.5 -0.3
Blood Eosinophil Count 0.6 4.3 7.4 -2.7 -1.1
Blood Platelet Count 0.6 6.8 13.5 -0.3 -3.7
Blood Red Count 0.2 1.7 3.1 -0.5 -1.8
Blood White Count 0.6 4.3 7.7 -0.9 -2.8
Heel T-Score 1.1 8.7 17.5 4.2 -0.0
BMI 0.4 2.1 3.8 -0.7 1.9
Height 0.9 17.4 31.8 -1.7 -5.6
Waist Hip Ratio (WHR) 0.5 2.3 2.8 1.7 -1.3
Systolic Blood Pressure 0.2 1.2 2.4 -1.5 -0.3
Smoking Status 0.7 1.8 3.2 0.6 -1.8
Allergy or Eczema 0.1 0.3 0.3 -0.6 0.4
Cardiovascular Disease 0.1 0.5 0.7 0.4 -0.9
Hypothyroidism (self reported) 0.5 1.1 1.7 0.7 1.3
Respiratory disease 1.2 2.7 3.3 1.4 -1.8
Type 2 Diabetes (T2D) (2018) 0.4 0.7 1.3 -0.3 -1.1
Lung FEV1/FVC ratio 1.3 6.6 12.5 -0.9 3.5
Lung FVC 0.4 2.0 3.1 -1.0 -1.8
Neuroticism 0.4 1.0 1.9 0.5 -1.4
Chronotype (morning person) 1.7 4.0 8.0 -0.1 2.8
Hair Pigment 0.0 0.8 1.5 0.4 -1.2
Tanning 0.0 0.6 0.7 0.8 -0.7
Hand grip strength (left) 0.9 2.3 4.1 2.0 -0.7
Number of treatments/medications taken 0.8 1.4 2.6 -1.6 -0.3
Average weekly spirits intake 1.0 1.2 2.4 0.2 1.6
Sensitivity / hurt feelings 1.4 2.3 4.7 2.2 -0.0
Frequency of depressed mood in last 2 weeks 0.4 0.6 1.0 -1.0 -0.5
Hearing difficulty/problems: Yes 0.2 0.3 0.4 -0.6 0.3
Relative age of first facial hair 0.4 0.8 1.5 1.2 -0.2
Other serious medical condition/disability diagnosed by doctor 0.0 0.0 0.0 0.2 0.1
Ever used hormone-replacement therapy (HRT) 0.2 0.3 0.5 -0.7 -0.0
Ever had hysterectomy (womb removed) 0.3 0.3 0.7 -0.8 0.1
Systolic blood pressure, automated reading 0.6 1.7 3.2 -1.8 0.5
Eye problems/disorders: Diabetes related eye disease 2.7 3.0 5.9 0.1 -2.4
Angina 0.1 0.2 0.2 -0.5 -0.3
Medication for hormone replacement therapy 2.8 3.2 5.1 -2.3 1.1
Vitamin and mineral supplements 0.1 0.1 0.3 0.5 -0.0
Supplements: Zinc 0.1 0.1 0.2 -0.4 0.3
Medication: Co-codamol 1.5 1.8 3.3 -0.5 1.8
Medication: Metformin 0.2 0.3 0.5 -0.4 -0.7
Diabetes (father) 1.4 1.7 2.4 -1.0 -1.5
Diabetes (mother) 0.1 0.1 0.1 -0.3 0.3
Severe depression (siblings) 0.1 0.1 0.2 0.4 -0.2
Pack years adult smoking proportion 0.2 0.2 0.4 -0.6 0.3
Impedance of leg (right) 0.2 0.9 1.7 0.1 -1.3
Leg fat-free mass (left) 0.1 0.4 0.9 -0.9 -0.1
Trunk fat percentage 0.3 1.3 2.1 -1.5 -0.7
Hand grip strength (right) 1.1 2.9 4.7 2.2 -1.0
Townsend deprivation index at recruitment 0.0 0.1 0.1 0.4 0.0
Current tobacco smoking 1.4 2.3 3.6 -1.9 -1.1
Average weekly fortified wine intake 3.4 4.0 4.5 -1.9 2.1
Maternal smoking around birth 0.5 0.7 1.0 0.6 -1.0
Fed-up feelings 0.5 1.0 1.2 1.1 -0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.3 0.5 0.7 0.4
Relative age voice broke 0.0 0.0 0.0 -0.0 -0.1
Taking other prescription medications 0.2 0.3 0.7 -0.8 0.1
Age when periods started (menarche) 0.1 0.3 0.6 0.8 -0.1
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.4 0.3 0.6
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.5 4.5 2.1 -0.6
Tinnitus: Yes, but not now, but have in the past 1.7 1.8 3.4 -1.8 0.4
Qualifications: CSEs or equivalent 0.1 0.1 0.2 0.4 -0.1
Serious illness, injury or assault to yourself 0.0 0.0 0.0 0.2 -0.2
High blood pressure 0.8 2.3 2.9 -1.3 -1.7
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.3 -0.2 0.5
Multivitamins +/- minerals 0.7 0.8 1.1 -0.7 -1.1
Stomach or abdominal pain in last month 0.7 0.9 1.6 -0.5 1.3
Supplements: Glucosamine 1.2 1.5 3.0 -1.7 -0.2
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 0.8 0.9 -0.6
Medication: Atenolol 0.2 0.3 0.6 -0.7 0.1
Medication: Levothyroxine sodium 1.0 1.6 2.2 1.0 1.5
Sitting height 0.9 6.1 11.9 -0.5 -3.5
Chronic bronchitis/emphysema (father) 0.8 0.9 1.2 0.8 -1.1
High blood pressure (mother) 0.4 0.5 0.6 -0.6 0.8
Body mass index (BMI) 0.3 1.1 1.3 -1.0 1.2
Impedance of leg (left) 0.5 2.6 4.8 0.7 -2.2
Leg predicted mass (left) 0.1 0.6 1.1 -1.1 -0.2
Trunk fat mass 0.3 1.1 1.4 -1.2 -0.9
Waist circumference 0.1 0.3 0.6 -0.4 -0.7
Number of incorrect matches in round 0.3 0.5 1.0 -0.1 -1.0
Past tobacco smoking 0.7 1.2 1.6 -0.9 1.3
Alcohol usually taken with meals 0.6 1.0 1.1 -0.9 1.0
Nervous feelings 0.1 0.1 0.3 -0.5 0.0
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 0.4 -0.6 -0.6
Hearing difficulty/problems with background noise 0.5 0.7 1.4 -1.2 0.3
Hair/balding pattern: Pattern 2 0.4 0.5 0.8 -0.9 0.4
Had menopause 3.9 4.9 8.5 -2.9 1.1
Had other major operations 1.3 1.6 2.2 -1.0 1.5
Forced vital capacity (FVC) 1.1 4.3 7.9 -0.8 -2.8
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 2.1 1.4 -0.2
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 2.0 1.4 -0.6
Qualifications: None of the above 0.2 0.4 0.4 0.7 0.6
Financial difficulties in last 2 years 0.8 1.0 1.9 1.4 0.4
Mouth/teeth dental problems 0.3 0.4 0.6 -0.4 -0.8
Heart attack 0.3 0.4 0.5 -0.7 -0.6
Allergy 0.0 0.0 0.0 0.1 -0.1
Pain all over the body in last month 0.1 0.1 0.1 -0.4 0.2
Diabetes (self-reported) 0.4 0.6 0.9 -0.9 -0.5
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 2.1 0.5 1.5
Medication: Ramipril 0.5 0.6 0.9 -1.0 0.6
Medication: Simvastatin 0.4 0.6 0.7 -0.9 0.6
Fluid intelligence score 0.0 0.1 0.1 -0.2 -0.4
Illnesses of siblings 1.5 2.1 2.7 1.2 -1.6
Neuroticism score 0.5 1.0 2.0 1.4 -0.3
Weight 0.1 0.6 0.8 -0.9 -0.7
Impedance of arm (right) 0.0 0.1 0.1 -0.2 -0.4
Arm fat percentage (right) 0.3 1.0 1.3 -1.2 0.8
Trunk fat-free mass 0.1 0.6 1.1 -0.4 -1.1
Hip circumference 0.3 1.5 2.2 -1.5 -0.9
Time employed in main current job 0.1 0.1 0.1 -0.4 0.3
Alcohol intake versus 10 years previously 0.0 0.1 0.1 -0.3 0.0
Father’s age at death 1.9 2.6 4.8 -0.6 2.2
Worrier / anxious feelings 0.4 0.8 0.9 0.8 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.3 -0.6 0.4
Falls in the last year 1.7 2.3 4.4 0.4 -2.1
Hair/balding pattern: Pattern 3 1.4 2.1 4.0 2.0 -0.4
Number of live births 0.9 1.3 2.5 1.6 0.1
Forced expiratory volume in 1-second (FEV1) 0.4 1.5 2.2 -0.9 -1.5
Pulse rate 0.7 1.2 1.2 1.1 -1.1
Happiness 4.0 4.9 6.9 -2.6 1.7
Noisy workplace 0.1 0.2 0.3 0.2 -0.5
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.1 -0.3 0.2
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 0.9 0.9 0.2
Mouth/teeth dental problems: Dentures 0.8 1.3 2.3 -0.6 1.5
Asthma 0.5 0.9 1.7 0.3 -1.3
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.8 0.1 -1.4
Medication: Cholesterol lowering 1.1 1.8 2.1 -1.2 1.4
Depression (self-reported) 1.2 1.5 2.8 0.3 -1.7
Medication: Lansoprazole 0.7 0.8 1.6 1.3 -0.0
Prospective memory result 0.2 0.3 0.5 0.7 -0.2
Lung cancer (father) 0.9 1.0 1.7 0.5 -1.3
Illnesses of mother 0.2 0.2 0.4 0.6 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 1.4 -0.7 -1.2
Pulse wave Arterial Stiffness index 0.8 0.9 1.4 -0.6 -1.2
Impedance of arm (left) 0.1 0.6 1.0 -0.4 -1.0
Arm fat mass (right) 0.1 0.3 0.6 -0.8 0.1
Trunk predicted mass 0.1 0.7 1.1 -0.4 -1.1
Standing height 0.8 8.3 16.6 -0.1 -4.1
Length of working week for main job 1.4 1.6 3.1 1.8 0.1
Exposure to tobacco smoke at home 0.2 0.2 0.2 -0.4 0.5
Breastfed as a baby 0.2 0.3 0.3 -0.5 0.6
Tense / ‘highly strung’ 0.0 0.1 0.1 -0.3 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.0 0.1 0.3 -0.2
Hair/balding pattern: Pattern 4 1.6 3.9 4.1 -2.0 1.9
Birth weight of first child 0.5 1.0 1.3 1.2 -0.8
Peak expiratory flow (PEF) 0.0 0.0 0.0 0.2 0.2
Pulse wave reflection index 1.1 1.4 2.5 -1.6 0.6
Ever highly irritable/argumentative for 2 days 0.5 0.5 0.8 0.5 -0.9
Loud music exposure frequency 3.1 3.4 3.7 1.9 -1.8
Qualifications: O levels/GCSEs or equivalent 4.1 6.6 11.0 1.5 -3.3
Mouth/teeth dental problems: Bleeding gums 1.7 2.1 2.3 1.5 -1.4
Blood clot in the leg (DVT) 0.8 1.0 1.7 -0.6 1.3
Medication: Paracetamol 0.9 1.5 2.3 1.5 -0.8
Headache pain in last month 0.1 0.2 0.3 -0.6 0.2
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.4 0.6 0.1
Glaucoma (self-reported) 0.0 0.0 0.1 -0.1 -0.2
Gout (self-reported) 0.1 0.1 0.2 0.2 -0.4
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 2.1 0.9 1.5
Medication: Amlodipine 1.4 2.0 3.9 0.2 -2.0
Medication: Ventolin 100micrograms inhaler 1.8 2.3 4.1 0.6 -2.0
Birth weight 0.5 1.1 1.2 0.9 -1.1
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.0 -1.4 -0.2
High blood pressure (siblings) 0.3 0.5 1.0 -0.2 1.0
Forced vital capacity (FVC), Best measure 0.8 2.8 5.3 -0.6 -2.3
Body fat percentage 0.1 0.5 0.9 -1.0 -0.3
Leg fat percentage (right) 0.1 0.4 0.4 -0.7 0.6
Arm fat-free mass (right) 0.2 1.0 1.3 -0.8 -1.2
Exposure to tobacco smoke outside home 0.8 1.1 1.3 -0.9 1.1
Comparative body size at age 10 0.0 0.1 0.1 -0.2 0.3
Number of full brothers 1.8 2.3 3.2 -1.8 1.2
Worry too long after embarrassment 1.0 1.6 3.3 1.8 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.2 1.4 1.2 -1.0
Wheeze or whistling in the chest in last year 1.1 2.0 3.9 0.2 -2.0
Number of children fathered 0.4 0.5 0.7 0.4 -0.9
Reason for reducing amount of alcohol drunk: Health precaution 3.3 3.8 6.4 -1.1 2.5
Age at first live birth 0.1 0.2 0.3 -0.6 0.1
Pulse wave peak to peak time 0.6 0.8 1.3 0.5 1.1
Health satisfaction 0.4 0.6 1.1 -1.1 -0.1
Shortness of breath walking on level ground 0.2 0.2 0.2 0.5 -0.5
Qualifications: College or University degree 1.1 3.6 4.6 -1.6 2.1
Eye problems/disorders: None of the above 0.2 0.2 0.4 0.7 0.2
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.0 1.0 -0.6
Emphysema/chronic bronchitis 0.1 0.1 0.1 0.3 -0.4
Medication for pain relief, constipation, heartburn 0.1 0.1 0.2 0.5 -0.1
Neck or shoulder pain in last month 0.3 0.4 0.8 -0.9 0.0
Medication: Blood pressure 0.2 0.3 0.4 -0.5 -0.6
Angina (self-reported) 0.2 0.3 0.6 -0.8 -0.1
Migraine (self-reported) 0.1 0.1 0.2 0.3 0.4
Medication: Ibuprofen 1.1 1.3 2.5 -0.1 -1.6
Medication: Allopurinol 0.2 0.3 0.5 0.1 -0.7
Medication: Omeprazole 3.0 3.6 4.0 -2.0 1.8
Medication: Seretide 50 evohaler 1.1 1.3 2.1 -1.5 0.7
Mean time to correctly identify matches 0.8 1.6 3.1 -1.8 0.2
Heart disease (mother) 0.1 0.1 0.2 -0.0 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.6 0.7 -0.1
Whole body fat mass 0.1 0.4 0.5 -0.7 -0.5
Leg fat mass (right) 0.1 0.2 0.5 -0.7 0.1
Arm predicted mass (right) 0.2 1.3 1.8 -0.8 -1.3
Pulse rate, automated reading 0.3 0.9 1.6 0.5 -1.3
Alcohol intake frequency. 0.3 0.7 1.1 1.0 -0.6
Comparative height size at age 10 0.6 3.5 5.4 -1.3 -2.3
Number of full sisters 0.4 0.5 0.6 0.7 -0.8
Suffer from ‘nerves’ 0.6 1.0 1.7 -1.3 0.6
Overall health rating 0.9 1.9 2.0 -1.3 -1.4
Chest pain or discomfort 0.8 1.2 2.1 -0.6 1.5
Had major operations 0.7 0.8 1.2 1.1 -0.7
Age at last live birth 0.1 0.2 0.2 0.5 -0.4
Family relationship satisfaction 0.7 0.8 1.0 -0.8 -1.0
Leg pain on walking 0.5 0.6 0.7 0.7 -0.8
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 1.0 -1.0 0.9
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.3 0.5 -0.6
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 0.9 0.3 -1.0
Medication: Aspirin 0.4 0.6 1.0 -1.0 0.4
Supplements: Vitamin C 2.3 2.7 4.7 -0.9 2.2
Knee pain experienced in last month 0.2 0.4 0.7 -0.9 -0.1
Hypertension (Self-reported) 0.9 2.5 2.8 -1.4 -1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 0.9 0.8 -0.9
Illnesses of father: Heart disease 0.1 0.1 0.1 0.3 -0.3
Illnesses of siblings: Diabetes 0.3 0.4 0.7 -0.3 0.8
Smoking status: Previous 1.6 2.4 4.1 2.0 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.5 4.8 -0.4 -2.2
Whole body fat-free mass 0.1 0.6 0.8 -0.6 -0.9
Leg fat-free mass (right) 0.1 0.3 0.4 -0.6 -0.6
Arm fat percentage (left) 0.2 0.9 1.2 -1.1 0.8
Average weekly red wine intake 0.1 0.1 0.2 -0.5 0.2
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.2 0.5 0.2
Mood swings 0.1 0.1 0.3 -0.0 -0.5
Loneliness, isolation 0.6 0.9 1.6 -0.4 1.3
Long-standing illness, disability or infirmity 0.8 1.2 1.5 -0.9 -1.2
Ever had bowel cancer screening 0.2 0.2 0.3 0.6 0.3
Diabetes diagnosed by doctor 0.5 0.9 1.2 -0.7 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 1.6 -1.2 1.2
Friendships satisfaction 0.9 1.1 2.2 -1.5 0.3
Qualifications: nursing, teaching 0.2 0.2 0.3 0.5 -0.4
Commuting to job workplace: Walk 1.2 1.3 2.1 -0.7 1.5
Eye problems/disorders: Cataract 1.2 1.4 2.7 -1.6 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.5 0.9 1.7 0.3 1.3
Medication for cholesterol 0.6 0.8 1.7 1.3 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.3 -0.2 -0.6
Back pain experienced in last month 1.5 2.2 2.7 1.3 -1.6
Mineral and other dietary supplements 3.0 4.0 7.4 2.7 -0.8
Breast cancer (self-reported) 2.5 3.0 5.8 0.3 2.4
Asthma (self-reported) 0.5 0.9 1.7 0.4 -1.3
Osteoporosis (self-reported) 0.3 0.3 0.5 -0.7 -0.4
Osteoarthritis (self-reported) 0.9 1.2 1.8 -0.8 1.3
Medication: Aspirin 0.4 0.5 0.8 -0.9 0.4
Medication: Gliclazide 0.5 0.6 0.8 0.6 -0.9
Illnesses of father: None of the above (group 1) 0.4 0.4 0.5 -0.6 0.7
Smoking status: Current 1.8 2.8 3.8 -2.0 -1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.1 0.4 1.0
Whole body water mass 0.1 0.6 0.8 -0.6 -0.9
Leg predicted mass (right) 0.1 0.4 0.6 -0.5 -0.8
Arm fat mass (left) 0.1 0.4 0.8 -0.9 0.1
Number of self-reported non-cancer illnesses 0.3 0.6 0.7 -0.9 0.6
Average weekly champagne plus white wine intake 1.1 1.4 2.8 0.3 1.7
Miserableness 0.3 0.5 0.5 0.7 -0.7
Guilty feelings 1.7 2.6 5.2 2.3 0.3
Wears glasses or contact lenses 0.7 0.8 0.9 -0.9 0.9
Ever taken oral contraceptive pill 0.8 0.9 1.8 0.2 -1.3
Hearing aid user 2.4 2.7 3.6 -1.9 1.3
Mother’s age at death 1.5 1.9 3.7 -0.2 1.9
Financial situation satisfaction 0.3 0.4 0.7 0.8 -0.4
Tinnitus: Yes, now most or all of the time 1.1 1.3 2.5 1.6 0.3
Commuting to job workplace: Public transport 0.2 0.2 0.3 -0.6 -0.4
Eye problems/disorders: Glaucoma 0.3 0.4 0.5 0.5 0.7
Medication: Blood pressure 0.1 0.2 0.3 -0.5 -0.5
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.3 0.5 0.5
Supplements: Fish oil (including cod liver oil) 1.9 2.4 4.0 -2.0 0.9
High cholesterol (Self-reported) 2.8 4.9 5.3 -2.3 2.1
Medication: Bendroflumethiazide 0.8 1.2 2.0 -1.4 -0.7
Medication: Paracetamol 1.4 2.2 2.3 1.5 -1.5
Medication: Lisinopril 0.4 0.5 0.9 -1.0 -0.3
Medication: Atorvastatin 0.6 0.7 1.5 -1.2 0.2
Illnesses of father: High blood pressure 1.4 1.7 3.2 -1.8 0.5
Alcohol drinker status: Never 0.6 0.8 1.5 -0.0 1.2
Ever smoked 0.6 1.1 2.2 0.0 -1.5
Basal metabolic rate 0.1 0.6 0.8 -0.7 -0.9
Leg fat percentage (left) 0.0 0.0 0.1 -0.3 0.0
Arm fat-free mass (left) 0.1 0.6 0.7 -0.6 -0.9
Number of operations (self-reported) 0.3 0.5 1.0 -0.2 1.0
Average weekly beer plus cider intake 0.3 0.5 0.8 0.9 0.5
Irritability 0.1 0.2 0.5 0.7 -0.2
Risk taking 0.2 0.3 0.6 0.8 -0.3
Ever had prostate specific antigen (PSA) test 1.2 1.4 2.8 -0.2 -1.7
Fractured/broken bones in last 5 years 1.4 1.8 3.5 -0.3 -1.9
Age started oral contraceptive pill 0.3 0.4 0.7 0.2 0.8
Diastolic blood pressure, automated reading 0.4 1.4 2.7 -1.6 0.2
Ever depressed for a whole week 0.2 0.3 0.6 0.7 0.1
Unable to work because of sickness or disability 0.2 0.3 0.5 -0.7 -0.4
Commuting to job workplace: Cycle 0.2 0.2 0.4 -0.6 0.4
Myopia 1.5 2.1 4.2 -2.0 0.2
Vascular/heart problems diagnosed by doctor 0.9 2.3 3.3 1.2 1.8
Cholesterol lowering medication 1.0 1.4 1.6 -1.3 -1.1
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 3.4 -1.9 1.1
Pain experienced in last month 0.0 0.0 0.0 0.0 0.1
Supplements: Calcium 0.8 0.9 1.7 -1.3 0.1
Basal cell carcinoma (self-reported) 0.2 0.2 0.5 0.0 0.7
Heart attack/myocardial infarction (self-reported) 0.3 0.3 0.4 -0.6 -0.5
Deep venous thrombosis (DVT) (self-reported) 0.7 0.8 1.6 -0.3 1.3
Heart disease (siblings) 4.6 5.6 8.1 -2.9 1.8
Alcohol drinker status: Previous 1.0 1.1 2.1 0.4 -1.5
Pack years of smoking 0.2 0.3 0.5 -0.7 0.2
Impedance of whole body 0.3 1.3 2.7 0.0 -1.6
Leg fat mass (left) 0.0 0.2 0.3 -0.5 -0.2
Arm predicted mass (left) 0.1 0.6 0.9 -0.5 -0.9